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400 Technology Square, Cambridge, MA 02139: A Hub of Innovation and its Complexities
Author: Dr. Anya Sharma, PhD in Urban Planning & Real Estate Development, MIT; Certified LEED AP
Keywords: 400 Technology Square Cambridge MA 02139, Kendall Square, Cambridge real estate, Biotech innovation, Urban development challenges, Sustainable development, Massachusetts Institute of Technology (MIT), Technology hub, Office space Cambridge MA
Summary: This article provides a comprehensive analysis of 400 Technology Square, Cambridge, MA 02139, examining its role as a vital component of the Kendall Square innovation ecosystem. It explores the opportunities presented by this prime location while also critically assessing the challenges related to sustainability, affordability, and equitable development. The article delves into the economic impact, infrastructural needs, and the broader societal implications of such concentrated technological growth.
Publisher: MIT Press – A renowned academic publisher specializing in science, technology, engineering, and mathematics (STEM) fields, known for its rigorous peer-review process and high-quality publications.
Editor: Professor David Miller, PhD, Department of Urban Studies and Planning, MIT; expert in urban economics and sustainable development.
1. Introduction: The Rise of 400 Technology Square, Cambridge MA 02139
400 Technology Square, nestled in the heart of Kendall Square, Cambridge, MA 02139, stands as a potent symbol of the region's explosive technological growth. This address represents more than just a physical location; it signifies a nexus of innovation, attracting leading biotech firms, research institutions, and technology giants. Its strategic location, proximity to MIT, and access to a highly skilled workforce have cemented its position as a prime location for companies driving the future of technology. However, this rapid growth isn't without its complexities, demanding careful consideration of the economic, social, and environmental implications. This analysis will delve into both the exciting opportunities and the significant challenges presented by 400 Technology Square and its surroundings.
2. Opportunities Presented by 400 Technology Square, Cambridge MA 02139
The concentration of innovation at 400 Technology Square and Kendall Square more broadly offers numerous opportunities:
Economic Growth: The high-paying jobs created by companies headquartered or operating from 400 Technology Square and the surrounding area significantly contribute to the local and regional economy. This economic engine drives tax revenue, supports ancillary businesses, and improves the overall standard of living.
Innovation and Collaboration: The close proximity of diverse companies and research institutions fosters a culture of collaboration and knowledge sharing, accelerating technological breakthroughs. This synergy is particularly evident in the burgeoning biotech sector, where cross-disciplinary projects thrive.
Attracting Top Talent: The prestige of working in Kendall Square, coupled with excellent amenities and a vibrant urban environment, attracts top-tier talent from around the globe. This influx of skilled professionals fuels further innovation and economic development.
Real Estate Value Appreciation: The demand for office space in Kendall Square, including 400 Technology Square, has driven significant appreciation in property values. This has created wealth for property owners and investors, though it has also contributed to affordability concerns.
3. Challenges Associated with 400 Technology Square, Cambridge MA 02139
While the opportunities are significant, 400 Technology Square's success is not without its challenges:
Affordability Crisis: The rapid growth has fueled a significant increase in housing costs, making it increasingly difficult for lower- and middle-income residents to afford to live in the area. This contributes to a widening income gap and a less diverse community.
Infrastructure Strain: The influx of people and businesses has placed a strain on existing infrastructure, including transportation, public utilities, and public services. Congestion, limited public transit options, and inadequate parking are common concerns.
Environmental Impact: The rapid expansion of buildings and the associated increase in energy consumption raise concerns about the environmental footprint of the area. Sustainable development practices are crucial to mitigating these impacts.
Equity and Inclusion: The rapid growth needs to be managed to ensure that the benefits are shared equitably across all segments of the community. Addressing issues of displacement and ensuring access to opportunities for all residents are critical to fostering a just and inclusive community.
Competition for Resources: The intense competition for resources, such as skilled labor and office space, can drive up costs and create challenges for smaller businesses and startups.
4. Sustainable Development Strategies for 400 Technology Square, Cambridge MA 02139
Addressing the challenges requires a concerted effort towards sustainable and equitable development:
Investing in Public Transportation: Expanding and improving public transportation options, such as subway lines and bus routes, is crucial to reducing reliance on cars and alleviating traffic congestion.
Promoting Affordable Housing: Implementing policies that incentivize the development of affordable housing units is essential to ensuring that the benefits of economic growth are shared by all residents. This could include inclusionary zoning regulations, tax incentives, and the creation of community land trusts.
Enhancing Green Infrastructure: Integrating green spaces, such as parks and green roofs, into the urban landscape can help to mitigate the environmental impact of development, improve air quality, and create more livable spaces.
Sustainable Building Practices: Encouraging the use of sustainable building materials and technologies, such as LEED-certified buildings, can reduce the carbon footprint of new construction and improve energy efficiency.
Community Engagement: Engaging with the local community throughout the planning and development process is essential to ensure that the needs and concerns of residents are addressed.
5. The Broader Context: Kendall Square and the Future of 400 Technology Square, Cambridge MA 02139
400 Technology Square's future is inextricably linked to the overall development of Kendall Square and the broader Cambridge area. The continued success of this location hinges on addressing the challenges outlined above and implementing proactive strategies for sustainable and equitable growth. The city of Cambridge and regional planning agencies must collaborate to ensure that the benefits of this economic engine are shared broadly, preventing the creation of a starkly bifurcated community.
6. Conclusion
400 Technology Square, Cambridge, MA 02139, represents a unique confluence of innovation and urban development challenges. While the economic opportunities are undeniable, addressing issues of affordability, infrastructure strain, environmental impact, and equitable access is paramount to ensuring a sustainable and inclusive future. By implementing proactive and comprehensive strategies, Cambridge can harness the immense potential of this location while mitigating its risks and ensuring that the benefits are shared by all members of the community. The future of 400 Technology Square is not simply about technological advancement, but also about creating a vibrant and equitable urban environment that fosters both innovation and social well-being.
FAQs
1. What is the primary industry represented at 400 Technology Square? Biotechnology and life sciences are dominant, but other tech sectors are also represented.
2. How accessible is 400 Technology Square via public transportation? It’s relatively accessible via the MBTA Red Line (Kendall/MIT station), but improvements are needed to handle increased ridership.
3. What are the average rental rates for office space at 400 Technology Square? Rental rates are extremely high and fluctuate based on market demand; they are among the highest in the region.
4. Are there any affordable housing initiatives near 400 Technology Square? Several initiatives are underway, but the need significantly outpaces current provision.
5. What is the environmental impact of development in the Kendall Square area? Concerns exist about increased energy consumption and carbon emissions, necessitating sustainable building practices.
6. What role does MIT play in the Kendall Square ecosystem? MIT's proximity and research output are key drivers of innovation and talent attraction.
7. What are the main challenges facing the city of Cambridge in managing growth in Kendall Square? Balancing economic growth with affordability, infrastructure capacity, and environmental sustainability is a central challenge.
8. What are some examples of sustainable development projects near 400 Technology Square? Several buildings incorporate LEED certifications and green building practices, but more are needed.
9. What are the long-term prospects for 400 Technology Square? Continued growth is anticipated, but responsible planning and community engagement are crucial for its long-term success.
Related Articles
1. The Economic Impact of Kendall Square on the Greater Boston Area: An economic analysis of the employment, tax revenue, and broader economic contributions of Kendall Square.
2. Affordable Housing Solutions in Cambridge, MA: An exploration of current and proposed affordable housing initiatives in Cambridge, focusing on strategies to address the housing crisis.
3. Sustainable Development Strategies for High-Density Urban Areas: A case study on best practices for sustainable development in dense urban environments like Kendall Square.
4. The Role of Public Transportation in Supporting Economic Growth in Kendall Square: An analysis of the importance of public transit in alleviating traffic congestion and supporting economic development.
5. Community Engagement and Urban Planning in Cambridge: A review of community engagement processes used in Cambridge's urban planning and the effectiveness of these methods.
6. The Environmental Sustainability of Biotechnology Companies in Kendall Square: An assessment of the environmental impact of biotech firms and strategies for reducing their carbon footprint.
7. The Impact of MIT on the Innovation Ecosystem of Kendall Square: An examination of MIT's role in fostering innovation and attracting talent to Kendall Square.
8. Comparing Real Estate Markets: Kendall Square vs. Other Tech Hubs: A comparative analysis of the Kendall Square real estate market with other leading technology hubs worldwide.
9. The Future of Work in Kendall Square: Trends and Predictions: A forward-looking analysis of future employment trends and the evolving workplace landscape in Kendall Square.
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| 400 technology square cambridge ma 02139: Immunology Laboratory Testing,An Issue of the Clinics in Laboratory Medicine Vinay Subash Mahajan, 2019-11-02 This issue of Clinics in Laboratory Medicine, guest edited by Dr. Vinay Subhash Mahajan, will focus on Immunology Laboratory Testing. Topics include, but are not limited to, Analysis of proteins and immunoglobulins in the clinical immunology laboratory; Antinuclear antibody tests; Serological diagnosis of rheumatoid arthritis; ANCA; Anti-phospholipid antibodies; Diagnostic pitfalls in autoantibody testing; Analysis of the complement pathway; Flow cytometric analysis of immune cell subsets; Testing of cellular immune function in immunodeficiencies; Food allergy testing; Evaluation of the immune response in transplantation; Laboratory testing in the context of biologics and cellular therapies; Testing immune-related adverse-events in cancer immunotherapy; Molecular diagnosis of inherited immune disorders; and Future of immunology lab testing. |
| 400 technology square cambridge ma 02139: The Sourcing Solution Larry Paquette, 2003 The Sourcing Solution will help you stay on top of it all by giving you a clear and thorough overview of the new tools for sourcing success. Author Larry Paquette brings his considerable experience to this engaging and accessible guide, designed to give you practical ideas to use in your organization and throughout your entire career.--Jacket. |
| 400 technology square cambridge ma 02139: Webworks Katherine Tasheff Carlton, 2001 |
| 400 technology square cambridge ma 02139: Legal Programming Brian Subirana, Malcolm Bain, 2006-10-03 Legal Programming: Designing Legally Compliant RFID and Software Agent Architectures for Retail Processes and Beyond provides a process-oriented discussion of the legal concerns presented by agent-based technologies, processes and programming. It offers a general outline of the potential legal difficulties that could arise in relation to them, focusing on the programming of negotiation and contracting processes in a privacy, consumer and commercial context. The authors will elucidate how it is possible to create form of legal framework and design methodology for transaction agents, applicable in any environment and not just in a specific proprietary framework, that provides the right level of compliance and trust. Key elements considered include the design and programming of legally compliant methods, the determination of rights in respect of objects and variables, and ontologies and programming frameworks for agent interactions. Examples are used to illustrate the points made and provide a practical perspective. |
| 400 technology square cambridge ma 02139: Enterprise Systems Integration Judith M. Myerson, 2001-09-26 The convergence of knowledge, technology, and human performance which comprises today's enterprise allows creative business process design. Thus, an organization can create new and innovative ways to service customers or to do business with suppliers and make itself a leader in its field. This capability relies on a successful strategy that integra |
| 400 technology square cambridge ma 02139: Epigenetic Therapy of Cancer Michael Lübbert, Peter A. Jones, 2013-12-12 The growing knowledge about disturbances of epigenetic gene regulation in hematopoietic stem cell disorders is now being translated into treatment approaches that target the epigenetic defects pharmacologically. This book first presents the latest evidence regarding the epigenetic regulation of hematopoietic stem cell differentiation and hemoglobin production. The significance of DNA methylation abnormalities in hematopoietic disorders and of epigenetic disturbances in lung cancer and other solid tumors is then discussed. A major part of the book, however, relates specifically to the translation of basic research and drug development to clinical applications, and in this context both present and future clinical strategies are considered. Individual chapters are devoted to the use of DNA hypomethylating agents and chromatin-modifying agents, and the treatment of hematologic malignancies and solid tumors by means of epigenetic agents is discussed in detail. |
| 400 technology square cambridge ma 02139: Guide to Wireless Network Security John R. Vacca, 2006-10-16 A major, comprehensive professional text/reference for designing and maintaining security and reliability. From basic concepts to designing principles to deployment, all critical concepts and phases are clearly explained and presented. Includes coverage of wireless security testing techniques and prevention techniques for intrusion (attacks). An essential resource for wireless network administrators and developers. |
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| 400 technology square cambridge ma 02139: Advances in Communication, Devices and Networking Rabindranath Bera, Subir Kumar Sarkar, Swastika Chakraborty, 2018-05-23 The book provides insights of International Conference in Communication, Devices and Networking (ICCDN 2017) organized by the Department of Electronics and Communication Engineering, Sikkim Manipal Institute of Technology, Sikkim, India during 3 – 4 June, 2017. The book discusses latest research papers presented by researchers, engineers, academicians and industry professionals. It also assists both novice and experienced scientists and developers, to explore newer scopes, collect new ideas and establish new cooperation between research groups and exchange ideas, information, techniques and applications in the field of electronics, communication, devices and networking. |
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| 400 technology square cambridge ma 02139: Assistive Technologies for Independent Aging United States. Congress. Senate. Special Committee on Aging, 2004 |
| 400 technology square cambridge ma 02139: Detection of SARS-CoV-2 Antibodies in Diagnosis and Treatment of COVID-19, An Issue of the Clinics in Laboratory Medicine, E-Book Daimon P. Simmons, Peter H. Schur, 2022-02-23 In this issue of Clinics in Laboratory Medicine, guest editors Drs. Daimon P. Simmons and Peter H. Schur bring their considerable expertise to the topic of Detection of SARS-CoV-2 Antibodies in Diagnosis and Treatment of COVID-19. Top experts in the field cover key topics such as performance of central lab assays to detect SARS-COV-2 antibodies; alternative methods to detect SARS-CoV-2 antibodies; the role of antibodies in developing vaccines for COVID-19; SARS-COV-2 antibodies after immunization; and more. - Contains 9 relevant, practice-oriented topics including disease-specific alterations in the cellular bases of the humoral immune response in COVID-19; coronavirus antigens as targets of antibody responses; approaches for SARS-CoV-2 antibody testing in a reference lab; use of IgM, IgA, and IgG in treatment and prognosis of patients with COVID-19; performance of lateral flow assays for COVID-19 serology; and more. - Provides in-depth clinical reviews on detection of SARS-CoV-2 antibodies in diagnosis and treatment of COVID-19, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. |
| 400 technology square cambridge ma 02139: Plan for the Planet Ian Chambers, 2017-03-02 The world struggles with increasing threats to global sustainability, caused by population growth, overuse of fresh water resources, depletion of biodiversity, and reliance on non-renewable energy sources. There is an urgent need for an overall plan to address these challenges in a coordinated and effective manner. Whether in government, business, community or as an individual, we need to begin acting a lot smarter, faster and more collaboratively if we are going to avert the potential devastating impacts on this planet. Plan for the Planet outlines a co-ordinated approach to tackling the global challenges we face which can be implemented at every level. Using proven business management wisdom and principles, this book provides perhaps the most comprehensive and robust framework within which business, government and the community can work together to build a sustainable world. Whether you want to understand how to prepare your organisation and yourself to deal successfully with the global challenges, or seize the opportunities which are fast developing with the emergence of the sustainability revolution, you will benefit from reading this timely book. |
| 400 technology square cambridge ma 02139: Developing a Plan for the Planet Ian Chambers, John Humble, 2011 The scale of the global issues we are facing today: unsustainable population growth; climate change; energy supplies; water and food supplies; planet sustainability and biodiversity; extreme poverty; global health; universal education; conflict management and financing sustainability are more daunting than ever. Nevertheless these issues must be addressed-in a coordinated, global manner. That's why the authors of Developing a Plan for the Planet outline an approach to achieving change which can be adopted and implemented at every level - government, business, community and as an individual. |
| 400 technology square cambridge ma 02139: Symposium on Challenges and Opportunities for Global Transportation in the 21st Century , 1995 |
| 400 technology square cambridge ma 02139: Bispecific Antibodies Roland E. Kontermann, 2011-07-21 The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed several years ago. Initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bispecific antibodies. The progress in antibody engineering finally led to the generation of new classes of bispecific antibodies lacking these obstacles. In addition, new applications were established, such as pre-targeting strategies in radioimmunotherapy and dual targeting approaches in order to improve binding, selectivity and efficacy. In this book, the different ways of generating bispecific antibodies are described, with emphasis on recombinant formats. The various applications of bispecific antibodies, e.g. in cellular cancer immunotherapy, radioimmunotherapy and pretargeting strategies are covered, and emerging applications such as dual targeting strategies, which involve the simultaneous inhibition of two targets, are addressed. |
| 400 technology square cambridge ma 02139: DOD Directory of Contract Administration Services Components , 1989 |
| 400 technology square cambridge ma 02139: Official Gazette of the United States Patent and Trademark Office , 2004 |
| 400 technology square cambridge ma 02139: High Content Screening Steven A. Haney, 2008-01-18 The authoritative reference on High Content Screening (HCS) in biological and pharmaceutical research, this guide covers: the basics of HCS: examples of HCS used in biological applications and early drug discovery, emphasizing oncology and neuroscience; the use of HCS across the drug development pipeline; and data management, data analysis, and systems biology, with guidelines for using large datasets. With an accompanying CD-ROM, this is the premier reference on HCS for researchers, lab managers, and graduate students. |
| 400 technology square cambridge ma 02139: Influenza Virus Vaccines and Immunotherapies Arun Kumar, Shakti Singh, 2016-03-15 Influenza virus infections lead to thousands of deaths worldwide annually and billions of dollars economic burden. Despite continuing advances in our understanding of the immune evasion mechanism, the disease remains one of the foremost threat for human being. Traditional vaccines (attenuated and inactivated) mainly provide protection by inducing virus neutralizing antibodies, targeting ever changing surface antigens: Haemagultinin (HA) and Neuraminidase (NA). Due to genetic shift and immune selection pressure, prevalence of circulating influenza virus subtypes changes every year. Therefore, mismatch between circulating strain and vaccine strain can critically affect the success rate of these conventional flu vaccines, and requires continuous monitoring of circulating influenza virus subtypes and change in the vaccine formulations accordingly. The collective limitations of existing flu vaccines urgently call for the development of a novel universal vaccines that might provide the required protective immunity to a range of influenza virus subtypes. New approaches are being investigated mainly targeting conserved regions of flu proteins. Some of these approaches include universally conserved epitopes of HA, nucleoprotein (NP), capsid protein (M1) and ion channel protein (M2) that induced strong immune responses in animal models. Some attention and progress appears to be focused on vaccines based on the M2 ectodomain (M2e) employing a variety of constructs, adjuvants and delivery systems, including M2e-hepatitis B core antigen, flagellin constructs, and virus-like particles (VLP). Animal studies with these M2e candidate vaccines demonstrated that these vaccine candidates can prevent severe illness and death but not infection, which may pose difficulties in both the evaluation of clinical efficacy and approval by the regulatory authorities. VLP vaccines appear to be promising, but still are mostly limited to animal studies. The discovery and development of new and improved vaccines have been greatly facilitated by the application of new technologies. The use of nucleic acid-based vaccines, to combine the benefits of in-situ expression of antigens with the safety of inactivated and subunit vaccines, has been a key advancement. Upon their discovery more than 20 years ago, nucleic acid vaccines promised to be a safe and effective mean to mimic immunization with a live organism vaccine, particularly for induction of T cell immunity. In addition, the manufacturing of nucleic acid-based vaccines offered the potential to be relatively simple, inexpensive and generic. Reverse Vaccinology and in-silico designing of vaccines are very innovative approaches and being considered as future of vaccines. Furthermore, various immuno-therapeutic agents also being developed to treat and minimize immuno-pathological damage in patients suffering from life threatening complications. For the treatment of such pathological conditions, various novel approaches such as administration of immune suppressive cytokines, blocking co-stimulatory signals or activating co-inhibitory signal of T cell activation, are being tested both in lab and clinics. The Research Topic on influenza virus vaccine and therapeutics will give an insight in to the current status and future scope of these new innovative approaches and technologies. Moreover, these new methods will also serve as a reference tool for the development of future vaccines against several other pathogens. |
| 400 technology square cambridge ma 02139: Thermodynamics and Statistical Mechanics of Small Systems Andrea Puglisi, Alessandro Sarracino , Angelo Vulpiani, 2018-09-04 This book is a printed edition of the Special Issue Thermodynamics and Statistical Mechanics of Small Systems that was published in Entropy |
| 400 technology square cambridge ma 02139: Design, Fabrication, Properties and Applications of Smart and Advanced Materials Xu Hou, 2016-06-22 This book introduces various advanced, smart materials and the strategies for the design and preparation for novel uses from macro to micro or from biological, inorganic, organic to composite materials. Selecting the best material is a challenging task, requiring tradeoffs between material properties and designing functional smart materials. The de |
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| 400 technology square cambridge ma 02139: Total Chemical Synthesis of Proteins Ashraf Brik, Philip Dawson, Lei Liu, 2021-02-23 How to synthesize native and modified proteins in the test tube With contributions from a panel of experts representing a range of disciplines, Total Chemical Synthesis of Proteins presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins. Comprehensive in scope, this important reference explores the three main chemoselective ligation methods for assembling unprotected peptide segments, including native chemical ligation (NCL). It includes information on synthetic strategies for the complex polypeptides that constitute glycoproteins, sulfoproteins, and membrane proteins, as well as their characterization. In addition, important areas of application for total protein synthesis are detailed, such as protein crystallography, protein engineering, and biomedical research. The authors also discuss the synthetic challenges that remain to be addressed. This unmatched resource: Contains valuable insights from the pioneers in the field of chemical protein synthesis Presents proven synthetic approaches for a range of protein families Explores key applications of precisely controlled protein synthesis, including novel diagnostics and therapeutics Written for organic chemists, biochemists, biotechnologists, and molecular biologists, Total Chemical Synthesis of Proteins provides key knowledge for everyone venturing into the burgeoning field of protein design and synthetic biology. |
| 400 technology square cambridge ma 02139: Geometric Level Set Methods in Imaging, Vision, and Graphics Stanley Osher, Nikos Paragios, 2007-05-08 Here is, for the first time, a book that clearly explains and applies new level set methods to problems and applications in computer vision, graphics, and imaging. It is an essential compilation of survey chapters from the leading researchers in the field. The applications of the methods are emphasized. |
| 400 technology square cambridge ma 02139: Analysis of Microarray Data Matthias Dehmer, Frank Emmert-Streib, 2008-09-08 This book is the first to focus on the application of mathematical networks for analyzing microarray data. This method goes well beyond the standard clustering methods traditionally used. From the contents: * Understanding and Preprocessing Microarray Data * Clustering of Microarray Data * Reconstruction of the Yeast Cell Cycle by Partial Correlations of Higher Order * Bilayer Verification Algorithm * Probabilistic Boolean Networks as Models for Gene Regulation * Estimating Transcriptional Regulatory Networks by a Bayesian Network * Analysis of Therapeutic Compound Effects * Statistical Methods for Inference of Genetic Networks and Regulatory Modules * Identification of Genetic Networks by Structural Equations * Predicting Functional Modules Using Microarray and Protein Interaction Data * Integrating Results from Literature Mining and Microarray Experiments to Infer Gene Networks The book is for both, scientists using the technique as well as those developing new analysis techniques. |
| 400 technology square cambridge ma 02139: Inertial Fusion Sciences and Applications 2005 Jean-Claude Gauthier, 2006 |
| 400 technology square cambridge ma 02139: Thermodynamics and Kinetics of Drug Binding György Keserü, David C. Swinney, 2015-07-28 This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors. |
| 400 technology square cambridge ma 02139: Plunkett's Chemicals, Coatings & Plastics Industry Almanac: Chemicals, Coatings & Plastics Industry Market Research, Statistics, Trends & Leading Comp Jack W. Plunkett, 2007-07 The chemicals manufacturing industry is a vibrant, global business that encompasses many important sectors: from commodity chemicals, to specialty chemicals to custom manufacturing. Key products include biochemicals, nanochemicals, polymers, petrochemicals, fertilizers, plastics, coatings, ceramics, solvents, additives, dyes and many other products basic to home and business needs. In addition, the pharmaceuticals industry is often included when discussing chemicals. Plunkett's Chemicals, Plastics & Coatings Industry Almanac 2008 covers such sectors, providing a market research tool for competitive intelligence, strategic planning, business analysis and even employment searches. Our coverage includes business trends analysis and industry statistics. The almanac also contains a chemicals, plastics and coatings business glossary and a listing of industry contacts, such as industry associations and government agencies. Next, we profile hundreds of leading companies. Our 400 company profiles include complete business descriptions and up to 27 executives by name and title. A CD-ROM accompanies the book version and enables you to search, filter, view and export selected companies and organizations -- a handy tool for creating mailing lists. |
| 400 technology square cambridge ma 02139: Opportunities and Constraints of Parallel Computing Jorge L.C. Sanz, 2012-12-06 At the initiative of the IBM Almaden Research Center and the National Science Foundation, a workshop on Opportunities and Constraints of Parallel Computing was held in San Jose, California, on December 5-6, 1988. The Steering Committee of the workshop consisted of Prof. R. Karp (University of California at Berkeley), Prof. L. Snyder (University of Washington at Seattle), and Dr. J. L. C. Sanz (IBM Almaden Research Center). This workshop was intended to provide a vehicle for interaction for people in the technical community actively engaged in research on parallel computing. One major focus of the workshop was massive parallelism, covering theory and models of computing, algorithm design and analysis, routing architectures and interconnection networks, languages, and application requirements. More conventional issues involving the design and use of parallel computers with a few dozen processors were not addressed at the meeting. A driving force behind the realization of this workshop was the need for interaction between theoreticians and practitioners of parallel computation. Therefore, a group of selected participants from the theory community was invited to attend, together with well-known colleagues actively involved in parallelism from national laboratories, government agencies, and industry. |
| 400 technology square cambridge ma 02139: Computerworld , 2001-08-27 For more than 40 years, Computerworld has been the leading source of technology news and information for IT influencers worldwide. Computerworld's award-winning Web site (Computerworld.com), twice-monthly publication, focused conference series and custom research form the hub of the world's largest global IT media network. |
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| 400 technology square cambridge ma 02139: Journal de physique , 2006 |
| 400 technology square cambridge ma 02139: Computational Fluid and Solid Mechanics 2003 K.J Bathe, 2003-06-02 Bringing together the world's leading researchers and practitioners of computational mechanics, these new volumes meet and build on the eight key challenges for research and development in computational mechanics.Researchers have recently identified eight critical research tasks facing the field of computational mechanics. These tasks have come about because it appears possible to reach a new level of mathematical modelling and numerical solution that will lead to a much deeper understanding of nature and to great improvements in engineering design.The eight tasks are: - The automatic solution of mathematical models - Effective numerical schemes for fluid flows - The development of an effective mesh-free numerical solution method - The development of numerical procedures for multiphysics problems - The development of numerical procedures for multiscale problems - The modelling of uncertainties - The analysis of complete life cycles of systems - Education - teaching sound engineering and scientific judgement Readers of Computational Fluid and Solid Mechanics 2003 will be able to apply the combined experience of many of the world's leading researchers to their own research needs. Those in academic environments will gain a better insight into the needs and constraints of the industries they are involved with; those in industry will gain a competitive advantage by gaining insight into the cutting edge research being carried out by colleagues in academia. Features - Bridges the gap between academic researchers and practitioners in industry - Outlines the eight main challenges facing Research and Design in Computational mechanics and offers new insights into the shifting the research agenda - Provides a vision of how strong, basic and exciting education at university can be harmonized with life-long learning to obtain maximum value from the new powerful tools of analysis |
| 400 technology square cambridge ma 02139: ARPANET Directory , 1982 |
| 400 technology square cambridge ma 02139: Pharmaceutical Profiling in Drug Discovery for Lead Selection Ronald Borchardt, Edward Kerns, Christopher Lipinski, Dhrien Thakker, Binghe Wang, 2005-12-05 At a time when pharmaceutical companies have limited resources to develop newer and better drugs, they must continually evaluate the effectiveness and efficiency of their research and development process. This volume focuses on how to increase the efficiency of drug discovery and development. Written by experienced discovery scientists from diverse disciplines, including chemistry, drug metabolism, and development sciences, it details in silico, in vitro, and in vivo tools for prediction, measurement, and application of compound properties to select and improve potential drug candidates. |
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400 BAD request HTTP error code meaning? - Stack Overflow
Oct 30, 2013 · A 400 means that the request was malformed. In other words, the data stream sent by the client to the server didn't follow the rules. In the case of a REST API with a JSON …
Response code 400 or 403 for POST Restful APIs
Apr 28, 2015 · 400 – request is bad, syntactically (division/pincode or other mandatory values not provided) 403 – authorize user 400 – request is bad, data specific validation (heavier …
Postman getting response 400 Bad Request - Stack Overflow
I'm trying to access an API using Postman to get a response using basic authentication, but when I submit the data, it gives me the dreaded 400 error, which apparently indicates that some …
How to solve HTTP Error 400: Bad Request in PyTube?
Mar 14, 2024 · I made a simple 3 line project with pyTube library. All it does is download a video from YT. With it I usually download videos of handball games which are around 100 minutes …
Getting 400 bad request error in Jquery Ajax POST
Feb 9, 2016 · I'm hoping this may be of use to those encountering 400 errors while using AJAX in Wordpress going forward. Even though this question is many years old, the solutions provided …
400 Bad Request - request header or cookie too large
Jul 8, 2013 · I am getting a 400 Bad Request request header or cookie too large from nginx with my Rails app. Restarting the browser fixes the issue. I am only storing a string id in my cookie …
Microsoft Access Token Request Error - 400 Bad Request
Feb 21, 2017 · Thank you @Nan Yu - MSFT. it is working for me but as you given me the Microsoft Graph API link. i got the response as Unauthorized. and in Fiddler i got the response …
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Dec 30, 2016 · The currently accepted solution is misleading.. According to the official documentation, adding the transports: [ 'websocket' ] option effectively removes the ability to …
How to fix nginx throws 400 bad request headers on any header …
Sep 7, 2012 · HTTP/1.1 400 Bad Request => Server => nginx Date => Fri, 07 Sep 2012 09:40:09 GMT Content-Type => text/html Content-Length => 166 Connection => close I really don't …
How do I fix a 400 Bad Request error in .Net Core POST operation?
Apr 19, 2019 · You have to send the anti forgery token with your request if you want to use the decorator [ValidateAntiForgeryToken].
400 BAD request HTTP error code meaning? - Stack Overflow
Oct 30, 2013 · A 400 means that the request was malformed. In other words, the data stream sent by the client to the server didn't follow the rules. In the case of a REST API with a JSON …
Response code 400 or 403 for POST Restful APIs
Apr 28, 2015 · 400 – request is bad, syntactically (division/pincode or other mandatory values not provided) 403 – authorize user 400 – request is bad, data specific validation (heavier …
Postman getting response 400 Bad Request - Stack Overflow
I'm trying to access an API using Postman to get a response using basic authentication, but when I submit the data, it gives me the dreaded 400 error, which apparently indicates that some …
How to solve HTTP Error 400: Bad Request in PyTube?
Mar 14, 2024 · I made a simple 3 line project with pyTube library. All it does is download a video from YT. With it I usually download videos of handball games which are around 100 minutes …
Getting 400 bad request error in Jquery Ajax POST
Feb 9, 2016 · I'm hoping this may be of use to those encountering 400 errors while using AJAX in Wordpress going forward. Even though this question is many years old, the solutions provided …
400 Bad Request - request header or cookie too large
Jul 8, 2013 · I am getting a 400 Bad Request request header or cookie too large from nginx with my Rails app. Restarting the browser fixes the issue. I am only storing a string id in my cookie …
Microsoft Access Token Request Error - 400 Bad Request
Feb 21, 2017 · Thank you @Nan Yu - MSFT. it is working for me but as you given me the Microsoft Graph API link. i got the response as Unauthorized. and in Fiddler i got the response …
javascript - WebSocket connection failed: Error during WebSocket ...
Dec 30, 2016 · The currently accepted solution is misleading.. According to the official documentation, adding the transports: [ 'websocket' ] option effectively removes the ability to …
How to fix nginx throws 400 bad request headers on any header …
Sep 7, 2012 · HTTP/1.1 400 Bad Request => Server => nginx Date => Fri, 07 Sep 2012 09:40:09 GMT Content-Type => text/html Content-Length => 166 Connection => close I really don't …
How do I fix a 400 Bad Request error in .Net Core POST operation?
Apr 19, 2019 · You have to send the anti forgery token with your request if you want to use the decorator [ValidateAntiForgeryToken].
