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| antidepressant study casts doubt: Ordinarily Well Peter D. Kramer, 2016-06-07 Do antidepressants work, or are they glorified dummy pills? How can we tell? In Ordinarily Well, the celebrated psychiatrist and author Peter D. Kramer examines the growing controversy about the popular medications. A practicing doctor who trained as a psychotherapist and worked with pioneers in psychopharmacology, Kramer combines moving accounts of his patients’ dilemmas with an eye-opening history of drug research to cast antidepressants in a new light. Kramer homes in on the moment of clinical decision making: Prescribe or not? What evidence should doctors bring to bear? Using the wide range of reference that readers have come to expect in his books, he traces and critiques the growth of skepticism toward antidepressants. He examines industry-sponsored research, highlighting its shortcomings. He unpacks the “inside baseball” of psychiatry—statistics—and shows how findings can be skewed toward desired conclusions. Kramer never loses sight of patients. He writes with empathy about his clinical encounters over decades as he weighed treatments, analyzed trial results, and observed medications’ influence on his patients’ symptoms, behavior, careers, families, and quality of life. He updates his prior writing about the nature of depression as a destructive illness and the effect of antidepressants on traits like low self-worth. Crucially, he shows how antidepressants act in practice: less often as miracle cures than as useful, and welcome, tools for helping troubled people achieve an underrated goal—becoming ordinarily well. |
| antidepressant study casts doubt: Methods of Behavior Analysis in Neuroscience Jerry J. Buccafusco, 2000-08-29 Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic |
| antidepressant study casts doubt: The Emperor's New Drugs Irving Kirsch, 2010-01-26 Do antidepressants work? Of course -- everyone knows it. Like his colleagues, Irving Kirsch, a researcher and clinical psychologist, for years referred patients to psychiatrists to have their depression treated with drugs before deciding to investigate for himself just how effective the drugs actually were. Over the course of the past fifteen years, however, Kirsch's research -- a thorough analysis of decades of Food and Drug Administration data -- has demonstrated that what everyone knew about antidepressants was wrong. Instead of treating depression with drugs, we've been treating it with suggestion. The Emperor's New Drugs makes an overwhelming case that what had seemed a cornerstone of psychiatric treatment is little more than a faulty consensus. But Kirsch does more than just criticize: he offers a path society can follow so that we stop popping pills and start proper treatment for depression. |
| antidepressant study casts doubt: Pharmacology and Physiology for Anesthesia E-Book Hugh C. Hemmings, Talmage D. Egan, 2018-10-19 Pharmacology and physiology are the foundation of every anesthesia provider's training and clinical competency. Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application, 2nd Edition, delivers the information you need in pharmacology, physiology, and molecular-cellular biology, keeping you current with contemporary training and practice. This thoroughly updated edition is your one-stop, comprehensive overview of physiology, and rational anesthetic drug selection and administration, perfect for study, review, and successful practice. - Contains new chapters on Special Populations (anesthetic pharmacology in obesity, geriatrics, and pediatrics), Oral and Non-IV Opioids, Thermoregulation, Physiology and Pharmacology of Obstetric Anesthesia, Chemotherapeutic and Immunosuppresive Drugs, and Surgical Infection and Antimicrobial Drugs. - Incorporates entirely new sections on Physics, Anatomy, and Imaging. - Includes new information on consciousness and cognition, pharmacodynamics, the immune system, and anti-inflammatory drugs. - Features user-friendly tables, figures, and algorithms (including 100 new illustrations), all presented in full color and designed to help explain complex concepts. - Helps you understand the molecular mechanism of drug actions and identify key drug interactions that may complicate anesthesia with dedicated sections on these areas. |
| antidepressant study casts doubt: Deadly Medicines and Organised Crime Peter Gotzsche, 2019-08-21 PRESCRIPTION DRUGS ARE THE THIRD LEADING CAUSE OF DEATH AFTER HEART DISEASE AND CANCER. In his latest ground-breaking book, Peter C Gotzsche exposes the pharmaceutical industries and their charade of fraudulent behaviour, both in research and marketing where the morally repugnant disregard for human lives is the norm. He convincingly draws close co |
| antidepressant study casts doubt: The Antidepressant Fact Book Peter Breggin, 2009-04-20 Known as the Ralph Nader of psychiatry, Dr. Peter Breggin has been the medical expert in countless court cases involving the use or misuse of psychoactive medications. This unusual position has given him unprecedented access to private pharmaceutical research and correspondence files, information from which informs this straight-talking guide to the most prescribed and controversial category of American drugs: antidepressants. From how these drugs work in the brain to how they treat (or don't treat) depression and obsessive-compulsive, panic, and other disorders; from the documented side and withdrawal effects to what every parent needs to know about antidepressants and teenagers, The Anti-Depressant Fact Book is up-to-the minute and easy-to-access. Hard-hitting and enlightening, every current, former, and prospective antidepressant-user will want to read this book. |
| antidepressant study casts doubt: Lost Connections Johann Hari, 2020-11-12 THE INTERNATIONAL BESTSELLER: A radically new way of thinking about depression and anxiety 'A book that could actually make us happy' SIMON AMSTELL 'This amazing book will change your life' ELTON JOHN 'One of the most important texts of recent years' BRITISH JOURNAL OF GENERAL PRACTICE 'Brilliant, stimulating, radical' MATT HAIG 'The more people read this book, the better off the world will be' NAOMI KLEIN 'Wonderful' HILLARY CLINTON 'Eye-opening' GUARDIAN 'Brilliant for anyone wanting a better understanding of mental health' ZOE BALL 'A game-changer' DAVINA MCCALL 'Extraordinary' DR MAX PEMBERTON Depression and anxiety are now at epidemic levels. Why? Across the world, scientists have uncovered evidence for nine different causes. Some are in our biology, but most are in the way we are living today. Lost Connections offers a radical new way of thinking about this crisis. It shows that once we understand the real causes, we can begin to turn to pioneering new solutions – ones that offer real hope. |
| antidepressant study casts doubt: Essentials of Discursive Psychology Linda M. McMullen, 2021 This guide explains how to conduct a discursive psychology research project. Such research explores how our use of language results in specific beliefs, versions of reality, and social actions. |
| antidepressant study casts doubt: International Review of Neurobiology , 1986-12-17 International Review of Neurobiology |
| antidepressant study casts doubt: Manic-Depressive Illness Frederick K. Goodwin, Kay Redfield Jamison, 2007-03-22 This long-awaited second edition of Manic-Depressive Illness will exhaustively review the biological and genetic literature that has dominated the field in recent years, and incorporate cutting-edge research conducted since publication of the first edition. Drs. Frederick Goodwin and Kay Redfield Jamison have updated their surveys of psychological and epidemiological evidence, as well as that pertaining to diagnostic issues, course, and outcome, and they offer practical guidelines for differential diagnosis and clinical management. This book will be a valuable addition to the libraries of psychiatrists and other physicians, psychologists, clinical social workers, neuroscientists, pharmacologists, and the patients and families who live with manic-depressive illness. |
| antidepressant study casts doubt: Mood Disorders Eric J. L. Griez, 2005-04-08 Written by an outstanding team of internationally recognised experts, this practical textbook is based on the European Certificate in Anxiety and Mood Disorders. It provides a thorough overview of diagnosis and treatment of mood disorders and analyses the most recent developments and scientific evidence. Covers the most important clinical topics in the field, including symptomatology, natural course and diagnosis Treatment strategies are reviewed in the light of all available empirical evidence Outstanding list of international contributors |
| antidepressant study casts doubt: Practical Psychopharmacology Joseph F. Goldberg, Stephen M. Stahl, 2021-04-29 A practical guide translating clinical trials findings, across major psychiatric disorders, to devise tailored, evidence-based treatments. |
| antidepressant study casts doubt: Studies on the Effectiveness of Antidepressant Drugs Aaron Smith, Elizabeth Traganza, Grace Harrison, 1969 |
| antidepressant study casts doubt: Common Mental Health Disorders National Collaborating Centre for Mental Health (Great Britain), 2011 Bringing together treatment and referral advice from existing guidelines, this text aims to improve access to services and recognition of common mental health disorders in adults and provide advice on the principles that need to be adopted to develop appropriate referral and local care pathways. |
| antidepressant study casts doubt: Textbook of Clinical Neuropsychiatry and Behavioral Neuroscience, Third Edition David Moore, Basant Puri, 2012-06-29 Highly Commended, BMA Medical Book Awards 2013Previously published as Textbook of Clinical Neuropsychiatry, this book has been re-titled and thoroughly updated, redesigned, and enhanced to include the fundamentals of neuroscience. This highly acclaimed text provides a definitive, clinically oriented, yet comprehensive book covering neuropsychiatry |
| antidepressant study casts doubt: Speaking of Sadness David Allen Karp, 2017 Speaking of Sadness, based on fifty in-depth interviews, provides first-hand accounts of the depression experience while discovering clear regularities in the ways that personal identities are shaped over the course of an illness career. The new edition of the book is highlighted by a thoroughly new and extensive introduction-- |
| antidepressant study casts doubt: Clinical Pharmacology in Psychiatry Svein G. Dahl, Lars F. Gram, Steven M. Paul, William Z. Potter, 2012-12-06 The Fourth International Meeting on Clinical Pharmacology in Psychiatry was held in Bethesda, Maryland on 5-8 September 1985 and was dedicated to the memory of Dr. Earl Usdin. Earl was one of the organizers of the three previous meetings held in Chicago (1979), Troms0 (1980), and Odense (1982). During the organization of the fourth meeting Earl became ill and had to relinquish his role as one of the principal organizers. It is safe to conclude that there was no better, or more professional, or more efficient an organizer of scientific meetings in the field of neuropharmacology and psychiatry than Earl U sdin, and it was quite a task for the remaining organizers to fill the void left when he withdrew from this one. Those of us who have organized previous meetings with Earl were struck by how much more difficult our work became without him. This obviously speaks well for his subtle (and at times not so subtle) organizational skills. Nevertheless, in Earl's memory the organizers proceeded to invite a group of internationally renowned neuropsychopharmacologists to address the problem of selectivity in psychotropic drug action and to try to reconcile the amazing advances in basic preclinical neuropsychopharmacology with the problem of clinical specificity encountered by the psychiatrist. |
| antidepressant study casts doubt: Blaming the Brain Elliot Valenstein, 2002-02 In Blaming the Brain Elliott Valenstein exposes the many weaknesses inherent in the scientific arguments supporting the widely accepted theory that biochemical imbalances are the main cause of mental illness. He lays bare the commercial motives of drug companies and their huge stake in expanding their markets. This provocative book will force patients, practitioners, and prescribers alike to rethink the causes of mental illness and the methods by which we treat it. |
| antidepressant study casts doubt: Drug Concentrations in Neuropsychiatry Ruth Porter, John Rivers, Julie Whelan, 2009-09-16 The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. |
| antidepressant study casts doubt: Interpersonal Psychotherapy for Depressed Adolescents Laura Mufson, 2004-04-22 Grounded in extensive research and clinical experience, this manual provides a complete guide to interpersonal psychotherapy for depressed adolescents (IPT-A). IPT-A is an evidence-based brief intervention designed to meet the specific developmental needs of teenagers. Clinicians learn how to educate adolescents and their families about depression, work with associated relationship difficulties, and help clients manage their symptoms while developing more effective communication and interpersonal problem-solving skills. The book includes illustrative clinical vignettes, an extended case example, and information on the model's conceptual and empirical underpinnings. Helpful session checklists and sample assessment tools are featured in the appendices. |
| antidepressant study casts doubt: Handbook of Developmental Disabilities Samuel L. Odom, Robert H. Horner, Martha E. Snell, 2009-01-21 This authoritative handbook reviews the breadth of current knowledge about developmental disabilities: neuroscientific and genetic foundations; the impact on health, learning, and behavior; and effective educational and clinical practices. Leading authorities analyze what works in intervening with diverse children and families, from infancy through the school years and the transition to adulthood. Chapters present established and emerging approaches to promoting communication and language abilities, academic skills, positive social relationships, and vocational and independent living skills. Current practices in positive behavior support are discussed, as are strategies for supporting family adaptation and resilience. |
| antidepressant study casts doubt: Neuroscience for Psychologists Marc L. Zeise, 2020-11-30 This textbook is intended to give an introduction to neuroscience for students and researchers with no biomedical background. Primarily written for psychologists, this volume is a digest giving a rapid but solid overview for people who want to inform themselves about the core fields and core concepts in neuroscience but don’t need so many anatomical or biochemical details given in “classical” textbooks for future doctors or biologists. It does not require any previous knowledge in basic science, such as physics or chemistry. On the other hand, it contains chapters that do go beyond the issues dealt with in most neuroscience textbooks: One chapter about mathematical modelling in neuroscience and another about “tools of neuroscience” explaining important methods. The book is divided in two parts. The first part presents core concepts in neuroscience: Electrical Signals in the Nervous System Basics of Neuropharmacology Neurotransmitters The second part presents an overview of the neuroscience fields of special interest for psychology: Clinical Neuropharmacology Inputs, Outputs and Multisensory Processing Neural Plasticity in Humans Mathematical Modeling in Neuroscience Subjective Experience and its Neural Basis The last chapter, “Tools of Neuroscience” presents important methodogical approaches in neuroscience with a special focus on brain imaging. Neuroscience for Psychologists aims to fill a gap in the teaching literature by providing an introductory text for psychology students that can also be used in other social sciences courses, as well as a complement in courses of neurophysiology, neuropharmacology or similar in careers outside as well as inside biological or medical fields. Students of data sciences, chemistry and physics as well as engineering interested in neuroscience will also profit from the text. |
| antidepressant study casts doubt: Talking Back to Prozac Peter R. Breggin, Ginger Ross Breggin, 2014-04-01 A psychiatrist takes a critical look at this SSRI and newer medications that are among the most frequently prescribed drugs in America. Prozac. Millions of Americans are on it. And just about everyone else is wondering if they should be on it, too. The claims of the pro‐Prozac chorus are enticing: that it can cure everything from depression (the only disorder for which Prozac was originally approved) to fear of public speaking, PMS, obesity, shyness, migraine, and back pain—with few or no side effects. But is the reality quite different? At what price do we buy Prozac‐induced euphoria and a shiny new personality? Psychiatrist Peter Breggin, MD, and coauthor Ginger Ross Breggin answer these and other crucial questions in Talking Back to Prozac. They explain what Prozac is and how it works, and they take a hard look at the real story behind today’s most controversial drug: The fact that Prozac was tested in trials of four to six weeks in length before receiving FDA approval The difficulty Prozac’s manufacturer had in proving its effectiveness during these tests The information on side effects that the FDA failed to include in its final labeling requirements How Prozac acts as a stimulant not unlike the addictive drugs cocaine and amphetamine The dangers of possible Prozac addiction and abuse The seriousness and frequency of Prozac’s side effects, including agitation, insomnia, nausea, diarrhea, loss of libido, and difficulty reaching orgasm The growing evidence that Prozac can cause violence and suicide The social and workplace implications of using the drug not to cure depression but to change personality and enhance performance Using dramatic case histories as well as scientific research and carefully documented evidence, the Breggins expose the potentially damaging effects of Prozac. They also describe the resounding success that has been achieved with more humane alternatives for the treatment of depression. Talking Back to Prozac provides essential information for anyone who takes Prozac or is considering taking it, and for those who prescribe it. |
| antidepressant study casts doubt: Foundations of Qualitative Research Jerry W. Willis, 2007-01-26 Willis catches the student up on relevant aspects of philosophy, empiricism, history, and prevailing political influences. This building of chronology is so valuable for students in understanding the origins of specific schools of thought in relations to a paradigm. —Heather T. Zeng, NACADA Foundations of Qualitative Research introduces key theoretical and epistemological concepts replete with historical and current real-world examples. Author Jerry W. Willis provides an invaluable resource to guide the critical and qualitative inquiry process written in an accessible and non-intimidating style that brings these otherwise difficult concepts to life. Key Features: Covers the conceptual foundations of interpretive, critical, and post-positivist paradigms: A thorough background of theory and social inquiry is given by looking at the development of each paradigm throughout history. Provides real-world examples: Cases illustrate different approaches to the same research problem so that students can better understand the contrasting features of these paradigms. Introduces seven qualitative research frameworks: In-depth coverage is provided on Altheide and Johnson′s Analytic Realism; Denzin and Lincoln′s Interpretive Perspective; Eisner′s Connoisseurship Model of Inquiry; Semiotics; the Phenomenological Psychological Model; Poststructuralism and Postmodernism; and Symbolic Interactionism. Offers general guidelines for qualitative research: Conceptually covers the best practices, approaches to data analysis, and interpretation of qualitative research. Examines emergent methods in qualitative research: New research areas such as PAR, emancipatory research, and participatory design research are included, as well as exemplary journal articles to further illustrate how theory links to research practice. Intended Audience: This text is designed for advanced undergraduate and graduate students taking their first or second qualitative research methods course in the fields of Education, Psychology, and the Health and Social Sciences. It is also an excellent theory companion supplement to the more applied qualitative methods text. |
| antidepressant study casts doubt: Functional Medicine for Antidepressant Withdrawal James Greenblatt, Jennifer C. Dimino, 2022-06-27 Since the days of the “Psychopharm Revolution,” antidepressant medications such as SSRIs and SNRIs have been a foundation of modern psychiatric practice. Today, 40 million Americans take antidepressants, and global antidepressant prescribing is on the rise. Simultaneously, however, a gap has emerged between pharmacologic innovation and methodology. Amidst patient reports of antidepressant side effects, evidence is mounting that antidepressant discontinuation often leads to withdrawal - which can be severe. And although today’s clinicians are trained how to prescribe antidepressants, they are not trained how to safely stop them. There is currently zero field-wide consensus regarding antidepressant discontinuation best practices. In addition to a stunning ethical failure, this represents a serious void in the psychiatric model... a riddle that too many patients and clinicians are being forced to solve alone. Functional Medicine for Antidepressant Withdrawal presents a comprehensive, evidence-based paradigm for antidepressant discontinuation that prioritizes the repletion of underlying nutritional deficiencies. Bridging concept and application, it provides health professionals with clinically proven tools for mitigating antidepressant withdrawal and guiding patients successfully through taper. It also reveals a path to the standard of care that we all deserve, one illuminated by science and upheld by the mandates of ethical, conscientious, personalized medicine. |
| antidepressant study casts doubt: Practical Psychiatric Epidemiology Jayati Das-Munshi, Tamsin Ford, Matthew Hotopf, Martin Prince, Robert Stewart, 2020-04-30 Epidemiology has been defined as the study of the distribution and determinants of health states or events in defined populations and its application to the control of health problems. Psychiatric epidemiology has continued to develop and apply these core principles in relation to mental health and mental disorders. This long-awaited second edition of Practical Psychiatric Epidemiology covers all of the considerable new developments in psychiatric epidemiology that have occurred since the first edition was published. It includes new content on key topics such as life course epidemiology, gene/environment interactions, bioethics, patient and public involvement in research, mixed methods research, new statistical methods, case registers, policy, and implementation. Looking to the future of this rapidly evolving scientific discipline and how it will to respond to the emerging opportunities and challenges posed by 'big data', new technologies, open science and globalisation, this new edition will continue to serve as an invaluable reference for clinicians in practice and in training. It will also be of interest to researchers in mental health and people studying or teaching psychiatric epidemiology at undergraduate or postgraduate level. |
| antidepressant study casts doubt: Pharmacotherapy of Depression Domenic A. Ciraulo, Richard Irwin Shader, 2010-12-28 Comprehensive and state of the art, the second edition of Pharmacotherapy of Depression offers major revisions of every chapter and the addition of new chapters by expert contributors. The first chapter reviews the neurobiology of depression, which lays the groundwork for understanding the mechanisms of action of antidepressants. In the next chapter, a review of the general principles guiding the diagnosis and medication treatment of unipolar depression is provided. The clinical pharmacology of antidepressants is reviewed in some detail, supplemented by tables that provide information on dosing, indications, and metabolism. Augmentation strategies are reviewed, including the use of non-traditional agents. The chapters that follow next address the use of antidepressants in special populations, such as the elderly and depressed individuals with psychosis, bipolar disorder, substance abuse, and post traumatic stress disorder. The complex issues involving the diagnosis and treatment of depression during pregnancy is thoroughly reviewed in Chapter 8 and provides a synthesis of the scientific literature in the area, one that is noted for contradictory and controversial findings, as well as guidelines for prescribing. The next chapter then provides an overview of the treatment of depression in the pediatric population, highlighting clinical concerns such as suicide risk. The book concludes with two chapters at the interface of medicine and psychiatry in the treatment of mood disorders: managing depression in primary care settings and depression associated with medical illnesses. The outstanding clinician-scientists who have contributed to this volume are all leaders in their fields and represent a broad spectrum of renowned institutions. A timely contribution to the literature, The Pharmacotherapy of Depression, Second Edition, offers busy clinicians from many disciplines a strong scientific foundation that seamlessly transitions into practical recommendations for clinical practice. The result is another gold-standard guide to the safe and effective use of the latest antidepressant medications. |
| antidepressant study casts doubt: The Sedated Society James Davies, 2017-01-23 This edited volume provides an answer to a rising public health concern: what drives the over prescription of psychiatric medication epidemic? Over 15% of the UK public takes a psychiatric medication on any given day, and the numbers are only set to increase. Placing this figure alongside the emerging clinical and scientific data revealing their poor outcomes and the harms these medications often cause, their commercial success cannot be explained by their therapeutic efficacy.Chapters from an interdisciplinary team of global experts in critical psychopharmacology rigorously examine how pharmaceutical sponsorship and marketing, diagnostic inflation, the manipulation and burying of negative clinical trials, lax medication regulation, and neoliberal public health policies have all been implicated in ever-rising psycho-pharmaceutical consumption. This volume will ignite a long-overdue public debate. It will be of interest to professionals in the field of mental health and researchers ranging from sociology of health, to medical anthropology and the political economy of health. |
| antidepressant study casts doubt: Drug Selectivity Norbert Handler, 2018-02-27 The book Drug Selectivity - An Evolving Concept in Medicinal Chemistry provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist. |
| antidepressant study casts doubt: Seminars in Clinical Psychopharmacology Peter M. Haddad, David J. Nutt, 2020 The 2nd edition of this book was edited by David King and published in 2004. Since then there have been major advances in psychopharmacology in terms of new medications coming to the market, increased understanding of the mechanisms of drug action and new data on the efficacy, tolerability, safety and clinical effectiveness of a range of medications. Partly as a result, clinical guidelines for many psychiatric disorders have altered. As such, a new edition of this textbook was essential and we were delighted when the College approached us to edit the 3rd edition. This was a major endeavor that was only possible with the commitment and expertise of the authors-- |
| antidepressant study casts doubt: Psychiatry Under the Influence R. Whitaker, L. Cosgrove, 2015-04-23 Psychiatry Under the Influence investigates the actions and practices of the American Psychiatric Association and academic psychiatry in the United States, and presents it as a case study of institutional corruption. |
| antidepressant study casts doubt: This Close to Happy Daphne Merkin, 2017-02-07 “A cleareyed, insightful account of how she felt during her nosedives into despair . . . shot through with a self-awareness that helps readers cheer her on.”—The New York Times A New York Times Book Review Favorite Read of the Year “Despair is always described as dull,” writes Daphne Merkin, “when the truth is that despair has a light all its own, a lunar glow, the color of mottled silver.” This Close to Happy—Merkin’s rare, vividly personal account of what it feels like to suffer from clinical depression—captures this strange light. Merkin has been hospitalized three times: first, in grade school, for childhood depression; years later, after her daughter was born, for severe postpartum depression; and later still, after her mother died, for obsessive suicidal thinking. Recounting this series of hospitalizations, as well as her visits to myriad therapists and psychopharmacologists, Merkin portrays the lifelong arc of her affliction, beginning in a childhood largely bereft of love and stretching into the present, where she lives a high-functioning life and her depression is manageable, if not “cured.” The opposite of depression, she writes with characteristic insight, is not a state of unimaginable happiness, but a state of relative all-right-ness. In this dark yet vital memoir, Merkin describes not only the harrowing sorrow that she has known all her life, but also her early, redemptive love of reading and gradual emergence as a writer. Written with an acute understanding of the ways in which her condition has evolved as well as affected those around her, This Close to Happy is an utterly candid coming-to-terms with an illness that is still often stigmatized and shrouded in misunderstanding. “[A] mesmerizing memoir.” —Booklist (starred review) “Brings a stunningly perceptive voice to the forefront of the conversation about depression, one that is both reassuring and revelatory.” —Carol Gilligan, author of In a Different Voice |
| antidepressant study casts doubt: Behavioral Emergencies, An Issue of Psychiatric Clinics of North America Nidal Moukaddam, Veronica Theresa Tucci, 2017-08-19 This issue of Psychiatric Clinics of North America, edited by Drs. Nidal Moukaddam, Veronica Tucci, will cover a wide arrange of topics in Behavioral Emergencies. Topics discussed in the issue include, but are not limited to: Medical Clearance of the Emergency Psychiatric Patient; Altered Mental State, Legal and Ethical Challenges in Emergency Psychiatry; Countertransference in the Clinical Setting; The Use of Psychotherapeutic Measures; Drugs of Abuse; Toxicological Emergencies in Patients With Mental Illness; Management of Depression and Suicidality in the Emergency Department; Special Considerations in the Pediatric Psychiatric Populations; Dementia and Special Considerations in the Geriatric Psychiatric Patient; The Changing Health Policy Environment and Behavioral Health Services Delivery; International Emergency Psychiatry Challenges; and Violence in the Emergency Department, among others. |
| antidepressant study casts doubt: Handbook of Affective Sciences Richard J Davidson, Klaus R Sherer, H. Hill Goldsmith, 2009-05-21 One hundred stereotype maps glazed with the most exquisite human prejudice, especially collected for you by Yanko Tsvetkov, author of the viral Mapping Stereotypes project. Satire and cartography rarely come in a single package but in the Atlas of Prejudice they successfully blend in a work of art that is both funny and thought-provoking. The book is based on Mapping Stereotypes, Yanko Tsvetkov's critically acclaimed project that became a viral Internet sensation in 2009. A reliable weapon against bigots of all kinds, it serves as an inexhaustible source of much needed argumentation and-occasionally-as a nice slab of paper that can be used to smack them across the face whenever reasoning becomes utterly impossible. The Complete Collection version of the Atlas contains all maps from the previously published two volumes and adds twenty five new ones, wrapping the best-selling series in a single extended edition. |
| antidepressant study casts doubt: Governmentality, Biopower, and Everyday Life Majia Holmer Nadesan, 2010-06-10 Governmentality, Biopower, and Everyday Life synthesizes and extends the disparate strands of scholarship on Foucault's notions of governmentality and biopower and grounds them in familiar social contexts including the private realm, the market, and the state/military. Topics include public health, genomics, behavioral genetics, neoliberal market logics and technologies, philanthropy, and the war on terror. This book is designed for readers interested in a rigorous, comprehensive introduction to the wide array of interdisciplinary work focusing on Foucault, biopower and governmentality. However, Nadesan does not merely reproduce existing literatures but also responds to implicit critiques made by Cultural Studies and Marxist scholarship concerning identity politics, political economy, and sovereign force and disciplinary control. Using concrete examples and detailed illustrations throughout, this book extends the extant literature on governmentality and biopower and helps shape our understanding of everyday life under neoliberalism. |
| antidepressant study casts doubt: Bipolar Disorder Francis Mark Mondimore, 2008-02-01 Bipolar disorder can be devastating. It can disrupt relationships and careers, it can wreak havoc on family life, and, when not properly treated, it can be fatal. Since 1999 this compassionate and comprehensive guide has helped tens of thousands of people cope with this complex disease. This, the second edition of Bipolar Disorder, is thoroughly updated and discusses promising new options for diagnosis and treatment along with new information on the disease's genetic components. Bipolar disorder is difficult to diagnose. Dr. Mondimore explains how symptoms fluctuate in persons with seasonal affective disorder, how they can lead to a mistaken diagnosis of attention deficit–hyperactivity disorder in children, and how they may be made worse by alcohol or drug addiction. The disease can also be difficult to treat. Dr. Mondimore gives advice about how to pick a psychiatrist and cope with the stigma of psychiatric diagnosis. He provides extensive information on treatment options, including the advantages, disadvantages, and side effects of various drug therapies. He also describes what it is like to live with bipolar disorder and discusses how lifestyle changes can improve quality of life. Throughout, he focuses on the importance of building a support system, planning for emergencies, and giving yourself permission to seek help. |
| antidepressant study casts doubt: Clinical Handbook of Psychotropic Drugs for Children and Adolescents Dean Elbe, Tyler R. Black, Ian R. McGrane, Sabina Choi, 2023-04-24 Quick and comprehensive information on psychotropic drugs for children and adolescents. Accurate and up-to-date Specific to children and adolescents Charts and tables help decision-making Icons and full color More about this book The Clinical Handbook of Psychotropic Drugs for Children and Adolescents is a unique resource to help you make the right choices about psychotropic medications for younger patients. The fifth edition of this widely acclaimed reference has been fully updated and expanded. Updated information on psychiatric disorders in children and adolescents Unique comparison charts (dosages, side effects, pharmacokinetics, interactions...) that allow you to see at a glance which medication is the most suitable for each patient Instantly recognizable icons in full color throughout, allowing you to quickly find all the information you seek: – General information on medications, availability, and indications – Drug action, dosing, pharmacokinetics, and related areas – Warnings and precautions – Patient-related information, such as lab monitoring recommendations, nursing implications, and patient advice Clearly written patient and caregiver information sheets as printable pdf files This book is a must for all mental health professionals working with children and adolescents who need an up-to-date, easy-to use, comprehensive summary of all the most relevant information about psychotropic drugs. New in this edition: New chapters on Prescribing Safely and Ethically to Children and Adolescents, Pharmacogenetic Information for Common Psychotropic Drugs, and Aggression Management in Children and Adolescents Neuroscience-based nomenclature added to Product Availability tables Antipsychotic-Induced Extrapyramidal Side Effect (EPSE) chapter completely revised, plus new section on monitoring scales for EPSE Anxiolytics section on buspirone and benzodiazepine comparison table revised |
| antidepressant study casts doubt: Clinical Trial Design Challenges in Mood Disorders Mauricio Tohen, Charles Bowden, Andrew A. Nierenberg, John Geddes, 2015-01-24 Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders. Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results. Traditional trial designs are included as well as novel analytic techniques. The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice. With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients. - Summarizes common trial design problems and their solutions - Encompasses funding, subject selection, regulatory issues and more - Identifies best practices for definitive and generalizable results - Includes traditional trial designs and novel analytic techniques - Represents academia, industry, regulatory agencies, and advocacy groups |
| antidepressant study casts doubt: Against Depression Peter D. Kramer, 2006-07-25 Deeply felt... [Kramer's] book is a polemic against a society that accepts depression as a fact of life. —O, The Oprah Magazine A profound look at depression by the author of The New York Times Bestseller, Listening to Prozac In his landmark bestseller Listening to Prozac, Peter Kramer revolutionized the way we think about antidepressants and the culture in which they are so widely used. Now Kramer offers a frank and unflinching look at the condition those medications treat: depression. Definitively refuting our notions of heroic melancholy, he walks readers through groundbreaking new research—studies that confirm depression's status as a devastating disease and suggest pathways toward resilience. Thought-provoking and enlightening, Against Depression provides a bold revision of our understanding of mood disorder and promises hope to the millions who suffer from it. |
| antidepressant study casts doubt: Handbook of Approach and Avoidance Motivation Andrew J. Elliot, 2013-05-13 Of the many conceptual distinctions present in psychology today, the approach-avoidance distinction stands out as one of, if not the, most fundamental and basic. The distinction between approach and avoidance motivation has a venerable history, not only within but beyond scientific psychology, and the deep utility of this distinction is clearly evident across theoretical traditions, disciplines, and content areas. This volume is designed to illustrate and highlight the central importance of this distinction, to serve as a one-stop resource for scholars working in this area, and to facilitate integration among researchers and theorists with an explicit or implicit interest in approach and avoidance motivation. The main body of this volume is organized according to seven broad sections that represent core areas of interest in the study of approach and avoidance motivation, including neurophysiology and neurobiology, and evaluative processes. Each section contains a minimum of four chapters that cover a specific aspect of approach and avoidance motivation. The broad applicability of the approach-avoidance distinction makes this Handbook an essential resource for researchers, theorists, and students of social psychology and related disciplines. |
List of Antidepressants + Uses, Types, Side Effects - Drugs.com
Apr 17, 2023 · An antidepressant is the name given to a medicine that can help relieve the symptoms of depression, such as low mood, anxiety, and …
Antidepressants: What They Are, Uses, Side Effects & Types
Mar 1, 2023 · Antidepressants are common prescription medications that can help treat depression and other conditions like anxiety and obsessive …
Antidepressant - Wikipedia
Antidepressants are prescribed to treat major depressive disorder (MDD), anxiety disorders, chronic pain, and some addictions. Antidepressants …
Depression Medications: Antidepressants Drugs for
Jun 16, 2024 · Depression medications are prescribed to treat depression. A doctor may prescribe them to you, alone or with talk therapy, after you …
Antidepressants: Selecting one that's right for you - May…
Antidepressants are a popular treatment choice for depression. Although antidepressants may not cure depression, they can reduce …
SStock Prices, Exchange Rates and Portfolio Equity Flows: …
The study casts doubt on the maintained hypothesis of a trivariate transmission channel, as posited by the portfolio model. Policy makers of an economy may integrate capital market and …
Archīum Ateneo - Ateneo de Manila University
Hydrol – in this feeding study casts doubt on the validity of the conclusions of this work regarding the effects of coconut oil. It was already known in the 1920s that hydrogenation of vegetable …
An Evolutionary Perspective on Panic Disorder and …
T he advances in ethology that have transformed the study of animal behavior are just now being applied to problems of psychopath- ology. Although most psychiatrists acknowledge the utility …
Many U.S. teens at risk for suicide despite treatment
(HealthDay)—A new study casts doubt on the value of current ... For the study, researchers collected data on suicidal behaviors among almost 6,500 teenagers. Fear, anger, distress, …
Soft Skills of Students Demonstrated during Internship
The study may give academic managers insights on the hiring preferences of employers for entry-level jobs. The findings in the study may help academic managers design learning tasks that …
Alienated Suffering of Divide and Cross: A Study of Amitav
Alienated Suffering of Divide and Cross: A Study of Amitav Ghosh’s The Shadow Lines Dr. Mohd Farhan Saiel Assistant Professor, Department of Languages, Integral University, Lucknow, …
The creation of the concept of an antidepressant: An …
study of the emergence of the concept of the antidepressant and the social forces that influenced its adoption. Historical literature documents the increasing importance of the specificity of …
Epidemics: The end of containment measures? - Phys.org
However, an EPFL study casts doubt on that idea, showing that such measures make a society less resilient and less able to return tor pre-epidemic economic and social conditions. The …
Longitudinal Analysis Casts Doubt on the Presence of …
Longitudinal Analysis Casts Doubt on the Presence of Genetic Anticipation in Heritable Pulmonary Arterial Hypertension Emma K. Larkin1, John H. Newman 2, Eric D. Austin3, Anna R. Hemnes …
Adiposity in middle and old age and risk of death
This study casts doubt on previous suggestions that obesity protects against dementia . Abstract Aims and objectives To examine the hypothesis that obesity is protective for dementia, we …
CASE STUDY 1 - Anxiety and Depression Association of …
CASE STUDY 1. ADAA, Miami, FL 9 April 2015 W. Edward Craighead, Ph.D. J. Rex Fuqua Professor and Vice Chair Emory University Psychiatry/Psychology ... Method of assessing …
Probabilistic Selling in Quality-Differentiated Markets - JSTOR
This casts doubt basic segmentation scheme inherent in probabilistic on the optimality of probabilistic selling in quality selling. Such arbitrage is relatively difficult in the case …
to Keep Changing Their Passwords Companies Should Stop …
frequent password change policies, led the authors to conclude “our study casts doubt on the utility of forced password expiration.” They found that, when faced with the need to change …
The Shroud on the Inernet - July 2023
the online introduction: “On a “Reason to Doubt” podcast recently I demonstrated, as I have done before, that the alleged wrist wound was demonstrably through the ‘palm’ of the hand rather …
Usage Patterns, Effects, and Subjective Experiences of Illicit …
centrality of alcohol casts doubt on this hypothesis of routine use leading to non-reporting). The teal cluster is dominated by stimulants and antidepressants, indicating the two groups of drugs …
Rethinking Postgraduate Studies: A Critical Analysis of …
practice, rather than study. The study casts doubt on the importance of advanced education qualifications to acquire jobs or career advancement in South Africa. Keywords: Johannesburg …
Point & Commentary Depression; Common, But Not a Cold
series of elegant studies that all known antidepressant treat-ments, including medications and electroshock, increase hippocampal neurogenesis. This work suggests that by interact-ing with …
Research reveals ancient Maya lessons on surviving drought …
A new study casts doubt on drought as the driver of ancient Mayan civilization collapse. 1/4. There is no dispute that a series of droughts occurred in the Yucatan
Minocycline and celecoxib as adjunctive treatments for …
This large trial casts doubt on the potential therapeutic benefits of adjunctive anti-inflammatory ... approval for the study (reference number 016/16), and the study protocol is available online. ...
A Patient With Lifelong Self-Doubt and Self-Criticism - The …
study. Cross Talk demonstrates that clinical ... Pharmacotherapy and ketamine assisted psychotherapy for treatment-resistant depression: a patient with lifelong self-doubt and self …
DIAGNOSTIC CAST – A FORGOTTEN DIAGNOSTIC TOOL …
the purpose of study and treatment planning (GPT). Accurate diagnostic casts transferred to a semiadjust-able articulator are essential for treatment planning in Prosthodontics, Orthodontics …
Study on Overcoming Fear & Anxiety - Biblical Counseling …
Guilt leads to fear, because guilt carries with it punishment. Love casts out fear. 1Jn 4:18 “There is no fear in love; but perfect love casts out fear, because fear involves punishment, and the one …
Lied-to children more likely to cheat and lie - Medical Xpress
The current study casts doubt on that belief." The study has implications not only for parenting but also for teaching scenarios and for forensic situations, said Carver: "All sorts of grown-4/5.
Volcanic super eruptions are millions of years in the …
This study casts doubt on the interpretation of prolonged storage of old ... study or research, no part may be reproduced without the written permission. The content is
Duty to Disclose Exculpatory Evidence - International …
e. Information that casts doubt on the credibility or accuracy of a witness or evidence. f. An inconsistent statement made orally or in writing by any proposed witness. g. Statements made …
University of Miami Law Review
But see: Indicates a holding that casts doubt upon the proposition in text, or upon the preceding cases cited. But cf: Indicates a decision suggesting an opposite result, although on ma-terially …
Cosmic Pollen Press Instructions
Study casts doubt on mammoth-killing cosmic impact. C.O. University of Manitoba Press, Winnipeg, pp. Cosmic ray and gamma ray dosimetry for TL and Electron-Spin-Resonance. …
What Do Dental Students Know About E-Cigarettes?
showed a generally inadequate level of knowledge about e-cigarettes, this study casts doubt on the competency of Palestinian dental students to offer cessation counseling, highlighting the …
Hand, foot, and mouth disease in mainland China - The Lancet
cases were included in their study, but whether or not the probable cases were misdiagnosed as hand, foot, and mouth disease was not mentioned. The fact that misdiagnosed cases of the …
TheBMJ Covid …
Covid-19: South Africa pauses use of Oxford vaccine after study casts doubt on efficacy against variant Author: Unknown Created Date: 20210208134554Z ...
Did socially responsible stocks perform better during the …
“New study casts doubt on the view of socially responsible stocks as rainy day assets” Gianfranco Gianfrate¹, Tim Kievid² and Mathijs van Dijk² – ¹EDHEC Business School, ²EUR As a …
AGA KHAN UNIVERSITY EXAMINATION BOARD …
Adapted from Huge New Study Casts Doubt on Conventional Wisdom about Fat and Carbs published in PBS News Hour Disclaimer: The article reports the results of a research study; …
The Excessive Profits of Defense Contractors: Evidence and …
hypothesis, though a more recent 2002 study casts doubt on the validity of this explanation. Rogerson (1992), Thomas and Tung (1992). McGowan and Vendrzyk (2002) • The academic …
From Resilience to Revolution: How Foreign Interventions …
iance among the three monarchies in this study casts doubt on royal exceptionalism. Moreover, the example of Bahrain’s monarchy battling its own mobilized opposition since 2011 fits the …
Variability of study cast assessment among orthodontists
(using study casts). The information from the study casts alone has a substantial impact on the diagnosis and subsequent treatment planning.2-5 However, research has demonstrated that …
When Mommy Comes to the Rescue of Statistics: Infants …
However, a recent study casts doubt on the robustness of early statistical word-learning (Johnson & Tyler, 2010). These authors presented 5- and 8-month-old Dutch-learning infants with two …
The Effect of Gerrymandering, Cracking, and Packing on …
the state government than those who are aligned with their district. This study casts doubt on the theory that trust in government causes lower voter turnout in gerry-mandered areas or that …
Financial Inclusion and Retirement Planning: A Scenario …
sector or low-income professions. However, the analysis presented in this study casts doubt on the efficacy of APY in fulfilling its intended objectives. The study reveals that at higher interest …
Chad M. Stefaniak, Ph.D., C.P.A. - University of South Carolina
“The Work Environment in Large Public Accounting Firms,” with Dana Hermanson, Rich Houston, and Anne Wilkins. Current Issues in Auditing (2016). “Using ‘The Wave’ to Facilitate Students’ …
Origins of the Legal Doctrine of Reasonable Doubt - JSTOR
This paper is a preliminary study in the historical development of an idea, the concept of reasonable doubt. This concept is used in criminal cases as a rule by which the jury (or judge) …
Analysis of the Conflict between Individual desires and …
women of color being subjugated," the study casts doubt on oversimplified accounts of personal empowerment. Volume 36, January 2025 ISSN 2581-5504 www.penacclaims.com Page 5 XII. …
Rethinking Postgraduate Studies: A Critical Analysis of …
This study examines the extent to which postgraduate studies correlate with career advancement in South Africa. We use ... rather than study. The study casts doubt on the importance of …
An update on the pharmacotherapeutic strategies for the …
inappropriate antidepressant study. In a study that recruited 801 individuals with DD, only one-third of patients received appropriate drug treatment [17]. Several types of antidepressants, …
Weight Gain and Antidepressants - The Journal of Clinical …
ings, a 12-month study26 of citalopram in depression showed that 4.7% of 541 patients reported a weight gain greater than 5 kg. My colleagues and I27 have recently completed a double-blind …
Abstract - ajbr.org
tus for objective measures in this study casts doubt on the overall value of using them to infer neighborhood quality. Such an argument ought to consider other rea-sons for the relatively low …
When One Cause Casts Doubt on Another: A Normative …
Often one cause casts doubt on another: "You become less con-fident that cause A was present when you are informed that an alternative cause B was present. Kelley (I972b) called this
Chapter 17: I. EXPLAINING THE INDUSTRIAL …
11. Explain why the rapid spread of industrialization across the world casts doubt on Europe’s uniqueness. 12. What two factors explain why the Industrial Revolution began first in Europe? …
Study Casts: Trimming and Marking - Augusta University
Articulate the casts to confirm that the study models properly represent the patient's current occlusion. Make sure no bubbles on occlusal surfaces interfere with how the teeth are …
With God on Their Side: The Religious Populism of
combat against a variety of evil forces; however, this comparative study casts doubt on oversimplified assertions that exclude the power of actual religious belief in both cases under …
Aga Khan University Examination Board Notes from E …
The Hugereading passage was an article titled New Study Casts Doubt on Conventional Wisdom about Fat and Carbs. Question 1a: Describe the author‟s purpose in writing this article. …
