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| anti-vegf therapy for macular degeneration: Management of Diabetic Retinopathy F. Bandello, M.A. Zarbin, R. Lattanzio, I. Zucchiatti, 2017-04-20 Recently developed diagnostic and therapeutic technologies such as OCT-angiography and small gauge vitrectomy have influenced the modern treatment of diabetic retinopathy. This volume provides a summary of the state-of-the-art evidence-based approach to managing complications that may occur with diabetic retinopathy. It offers the latest information on pathogenesis and diagnosis, and highly experienced clinicians review the results of relevant randomized clinical trials that serve as the basis of current therapy. The book provides not only a summary of data from randomized trials but also an analysis and interpretation by internationally renowned experts. Ophthalmology residents, fellows, and practicing clinicians will find this book to be a useful reference when seeking evidence-based treatment strategies for various complications of diabetic retinopathy. It is also for researchers identifying new avenues of drug developments and for insurance professionals and health care policy administrators who are establishing evidence-based therapy guidelines for therapeutic intervention. |
| anti-vegf therapy for macular degeneration: Therapeutic Antibodies Yuti Chernajovsky, Ahuva Nissim, 2007-11-22 This essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes. |
| anti-vegf therapy for macular degeneration: Anti-VEGF Francesco Bandello, Maurizio Battaglia Parodi, A. J. Augustin, 2010-01-01 The development of therapy with anti-angiogenics or vascular endothelial growth factor inhibitors (anti-VEGF) has marked the beginning of a new era in neovascularization and macular edema treatment. Its main goals are the inhibition of growth and development of new vessels along with the reduction of vascular permeability. The advantages over conventional laser photocoagulation are evident as laser treatment always leaves scars and causes a retinal sensitivity deterioration. Starting with an outline of treatment principles, this volume covers all aspects of anti-VEGF therapy for ophthalmological disorders. In particular, specific chapters are dedicated to age-related macular degeneration, degenerative myopia, angioid streaks, inflammatory diseases, hereditary dystrophies, retinal vein occlusion, diabetic retinopathy, ocular tumors, as well as anterior segment neovascularization. The book gives an update on the application of anti-VEGF in ocular diseases to general ophthalmologists as well as retina specialists. |
| anti-vegf therapy for macular degeneration: Webvision Helga Kolb, Eduardo Fernandez, Ralph Nelson, 2007 |
| anti-vegf therapy for macular degeneration: Retinal and Choroidal Angiogenesis John Penn, 2008-01-19 This book provides a comprehensive, in-depth review of our current understanding of the growth of blood vessels within the eye. Novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye. The book emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance. |
| anti-vegf therapy for macular degeneration: Ocular Angiogenesis Joyce Tombran-Tink, Colin J. Barnstable, 2007-11-06 Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches. |
| anti-vegf therapy for macular degeneration: Vitreous Microsurgery Steve Charles, Jorge Calzada, Byron Wood, 2012-03-28 Written by a pioneering leader in the development of vitreoretinal surgical techniques and instruments, Vitreous Microsurgery is a comprehensive how-to guide to all vitreoretinal procedures. This thoroughly updated Fifth Edition describes many new techniques and refinements of established procedures. More than 170 three-dimensional full-color illustrations—many by the Charles Retina Institute's resident medical artist, Byron Wood—enable surgeons to clearly visualize the techniques. This edition has new chapters on the Constellation vitrectomy system, uveitis, retinal complications of permanent keratoprosthesis, and anti-VEGF therapy and completely rewritten chapters on anesthesia and on retinopathy of prematurity. All illustrations have been updated, the majority to a 25-gauge approach instead of 20-gauge, and many new illustrations have been added. Many techniques and parameters unique to 25-gauge sutureless vitrectomy are discussed in detail. A companion website offers the fully searchable text and an image bank. |
| anti-vegf therapy for macular degeneration: Optical Coherence Tomography of Ocular Diseases Joel S. Schuman, James G. Fujimoto, Jay S. Duker, Hiroshi Ishikawa (Professor of ophthalmology and biomedical engineering), Gadi Wollstein, 2022 Optical Coherence Tomography of Ocular Diseases, Fourth Edition covers a range of subjects, from principles and operation techniques to clinical interpretation and the latest innovations in OCT. This book is an essential text for imaging technology. OCT now occupies a dominant role as a diagnostic tool for retinal conditions and glaucoma. At the same time, the technology continues to show potential for emerging clinical and research applications across all the ophthalmological subspecialties. To reflect these rapid advances, this new edition of Optical Coherence Tomography of Ocular Diseases features a complete and thorough revision of the existing text as well as the addition of cutting-edge content to bring this classic resource completely up to date-- |
| anti-vegf therapy for macular degeneration: Intravitreal Steroids Albert J. Augustin, 2015-02-19 This book explains how to use intravitreal steroids optimally in the management of patients with intraocular inflammation (uveitis) and macular edema. The rationale for this treatment approach is first explained by examining the pathophysiology of these disease entities, with particular attention to the major role of inflammatory processes. Devices for the delivery of steroids to the eye are discussed, and guidance provided on the role of imaging studies before, during, and after steroid therapy. The value of different steroidal approaches is then considered in detail. Other topics addressed include the use of steroids as a surgical adjunct and within a combination strategy. Uveitis and macular edema are common sight-threatening diseases or complications of diabetes and retinal vein occlusion for which no adequate treatment was available until recently. Both trainees and practitioners will find Intravitreal Steroids to be an invaluable aid in combating these blinding diseases. |
| anti-vegf therapy for macular degeneration: Age-related macular degeneration (ARMD) Sics Editore, 2014-10-01 Age-related macular degeneration is the most important cause of visual impairment in the elderly. The non-exudative or dry form progresses slowly, the exudative or wet form rapidly (within weeks or months). Refer a patient with suspected exudative form of the disease without delay for investigations and treatment. Also consider the significance of the disease in the patients' daily life. |
| anti-vegf therapy for macular degeneration: Retinal Gene Therapy Camiel J.F. Boon, Jan Wijnholds, 2017-11-29 This detailed volume describes a spectrum of methods and protocols that can be used for the bench-to-bedside development and evaluation of retinal gene therapy. Methods for the successful delivery of these gene therapy vector systems to the retina are examined, as well as assays to test the efficacy in vitro in cell cultures, for gene augmentation and gene editing in vivo on rodents, pigs, and monkey retinas, and on human retinal explants as well as in human clinical studies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Retinal Gene Therapy: Methods and Protocols provides a wide range of readers from students to research experts with vital information on ocular gene therapy vector technology, in vitro and in vivo biological assays, and clinical protocols, to promote further studies for the benefit of children and adults with inherited retinal disease. |
| anti-vegf therapy for macular degeneration: Common Eye Diseases and Their Management N. R. Galloway, Winfried Mawutor Kwaku Amoaku, 1999 This book presents a problems-oriented approach to the diagnosis and treatment of common eye diseases. The text concentrates on common eye diseases which are likely to be seen by general practitioners and optometrists at the primary care level. |
| anti-vegf therapy for macular degeneration: Macular Disorders Ivana K. Kim, 2020-05-27 This atlas presents chapters on common and rare macular diseases including variants of age-related macular degeneration (dry, neovascular, polypoidal choroidal vasculopathy), cystoid macular edema, macular telangiectasia, central serous retinopathy and pachychoroid disease, photic retinopathy, presumed ocular histoplasmosis syndrome, myopic degeneration, angioid streaks, and a recently described entity: perifoveal exudative vascular anomalous complex. It provides a wealth of representative images, using various modalities to help the reader recognize the respective conditions. Importantly, it also includes images acquired using techniques more recently adopted in clinical practice such as autofluoresence, optical coherence tomography (OCT), and OCT angiography. The concise text reviews the basic concepts of etiology, diagnosis, and management in a highly accessible format. In contributions prepared by internationally respected experts, the atlas provides a cutting-edge analysis of each condition, as well as excellent summaries of recent work in the field. Macular Disorders is one of nine volumes in the series Retina Atlas. The series offers a global perspective on vitreoretinal diseases, covering imaging basics, retinal vascular disease, ocular inflammatory disease, retinal degeneration, surgical retina, macular disorders, ocular oncology, pediatric retina and trauma. In nine volumes and over 100 chapters, Retina Atlas offers comprehensive and validated information on retinal disorders. |
| anti-vegf therapy for macular degeneration: Optical Coherence Tomography in Age-Related Macular Degeneration Gabriel Coscas, 2009-07-25 Rapid or even dramatic progress has been made in the field of AMD over recent years, leading to a constant revision of basic concepts. A wide range of fundus imaging modalities are now available, and this book explains the respective value of each technique. The information provided by OCT is presented logically by comparison with plain films, autofluorescence, fluorescein angiography, or indocyanine green angiography. Meticulous biomicroscopic examination of macular changes and the essential value of fluorescein angiography for the detection of anatomical alterations of the macula and for precise evaluation of lesions and their course by indocyanine green angiography have naturally led the author Gabriel Coscas to analyze the new data provided by OCT. |
| anti-vegf therapy for macular degeneration: Pathologic Myopia Richard F. Spaide, Kyoko Ohno-Matsui, Lawrence A. Yannuzzi, 2021-07-28 Pathologic Myopia is a major cause of severe vision loss worldwide. The mechanisms for vision loss include cataract, glaucoma, retinal detachment, and above all, myopic maculopathy within the posterior staphyloma. The first edition of Pathologic Myopia is one of the only current books to specifically address this disease and discusses recent developments in imaging technologies and various approaches to treatments, such as laser photocoagulation, photodynamic therapy, pharmaco-therapeutic injections in the vitreous, and surgery. This new edition is a timely update to the standard reference in the field, with new chapters on advanced refractive error correction, genetics, developing a classification system, and special surgical approaches for pathologic myopia. Complete with even more high-quality color images and informative tables, this book is written and edited by leaders in the field and is geared towards ophthalmologists, including residents and fellows in training, glaucoma and cataract specialists, and vitreoretinal macula experts. |
| anti-vegf therapy for macular degeneration: Retinal Pharmacotherapeutics Q.D. Nguyen, E.B. Rodrigues, M.E. Farah, W.F. Mieler, D.V. Do, 2015-10-27 The use of pharmacotherapeutics in the management of retinal diseases is rapidly evolving, and a favorable therapy for the patient. Today anti-VEGF agents are used for a range of indications from inflammation-related choroidal neovascularization to macular edema secondary to retinal vein occlusion or diabetic retinopathy. Beyond VEGF, there is an array of target areas under investigation – not only for vascular pathologies such as age-related macular degeneration and diabetic eye disease, but also for degenerative, infectious and inflammatory retinal conditions. This publication discusses many aspects from basic research on the retina, to animal models for retinal drug delivery, retinal diseases that are amenable to pharmacotherapy and also drugs and mechanisms in retinal diseases. Anyone concerned with the management of retinal diseases - the general ophthalmologist and the retina specialist alike – will find this book indispensable reading. |
| anti-vegf therapy for macular degeneration: Clinical Retina David A. Quillen, Barbara A. Blodi, 2002 Each condition in this book is presented in a standard format including general information, symptoms, clinical features, ancillary tests, pathology, treatment, systematic evaluation and selected references. |
| anti-vegf therapy for macular degeneration: Ocular Vascular Occlusive Disorders Sohan Singh Hayreh, 2015-02-18 This book provides a comprehensive account of the pathogenesis, clinical features, and management of ocular vascular occlusive disorders, with the focus very much on the scientific evidence. This offers a sound basis for addressing the many controversies that surround these disorders, which collectively constitute the most common cause of visual impairment or blindness. The book is divided into two sections, the first of which addresses the basic science and encompasses vascular anatomy, blood supply and flow, and retinal tolerance time to acute ischemia. The second, clinical, section covers the presentation, clinical features, diagnosis, and treatment of the full range of vascular occlusive disorders of the retina, the choroid, the anterior segment of the eye, ophthalmic manifestations of carotid artery disease and the optic nerve. Ocular Vascular Occlusive Disorders, written by a distinguished world leader in the field, will be invaluable for general ophthalmologists, and particularly for retina specialists, neuro-ophthalmologists, and researchers. |
| anti-vegf therapy for macular degeneration: Ophthalmic Literature , 1917 |
| anti-vegf therapy for macular degeneration: Fundus Autofluorescence Noemi Lois, John V. Forrester, 2012-02-13 Featuring over 250 illustrations, this detailed full-color textbook provides up-to-date information on the use of fundus autofluorescence imaging in evaluation of retinal disease. Chapters describe the techniques available to image and quantify fundus autofluorescence and the autofluorescence patterns observed in the healthy eye and in various retinal diseases. Emphasis is on the value of fundus autofluorescence as a diagnostic and prognostic tool and its clinical utility in the context of other imaging techniques, such as fluorescein and indocyanine green angiography and optical coherence tomography. Each chapter also discusses the value of fundus autofluorescence in understanding the pathogenesis of the condition, and provides a comprehensive update on all aspects of the condition. A companion Website will offer the fully searchable text and an image bank. |
| anti-vegf therapy for macular degeneration: Macular Dystrophies Giuseppe Querques, Eric Souied, 2016-02-15 This book provides the ophthalmologist with the most recently available data on the macular dystrophies, a group of many different inherited or sporadic eye conditions linked by a problem with photoreceptors or other structures of the central retina. Internationally recognized experts in the field present the latest evidence and discuss their own personal experiences with regard to each of the principal dystrophies as well as some very rare entities. Topics covered include molecular biology, state-of-the-art diagnostic techniques, and the newest treatment options, including still experimental therapies. Attention is also devoted to a range of issues that continue to be debated. The editors have taken care to ensure that chapters are of a uniformly high standard while not sacrificing the originality of the individual authors. Macular Dystrophies will fully acquaint the reader with both the latest research findings and the current and emerging approaches to diagnosis and treatment. |
| anti-vegf therapy for macular degeneration: Oxford Handbook of Ophthalmology Alastair K. O. Denniston, Philip I. Murray, 2018-05-24 Fully revised and updated throughout, the fourth edition of the Oxford Handbook of Ophthalmology now includes free access to the ophthalmic online media bank, a selection of high-quality clinical images and videos for a wide breadth of key ophthalmic diseases. Clear, concise, and practical, this handbook provides immediate access to the detailed clinical information you need, in casualty, clinic, theatre, and on the wards. The core of the book comprises a systematic synopsis of ophthalmic disease directed towards diagnosis, interim assessment, and ongoing management. Assessment boxes for common clinical conditions and algorithms for important clinical presentations illustrate this practical approach. The information is easily accessible, presented in a clear format with areas of importance highlighted. Key sections for the trainee include: Clinical Skills, Aids to Diagnosis, Investigations and their Interpretation, Perioperative Care, Theatre Notes and Therapeutics. The wider practise of eye-care is supported by expanded chapters on Refractive Ophthalmology, Vision in Context, Evidence Based Ophthalmology and Resources for Ophthalmologists. Now including newer treatments across a range of specialities such as SMILE, gene-therapy and retinal prostheses, as well as greater emphasis on the evidence underlying current clinical practice and guidelines, this handbook has never been more essential for all those working in eye-care. Whether you want to learn about patient-reported outcomes, identify a surgical instrument, interpret a statistical test, or diagnose and treat ophthalmic emergencies, you will find it here. Whatever your role in caring for patients with eye disease: ophthalmologist, optometrist, orthoptist, ophthalmic nurse, or other health profession - discover for yourself why this handbook has become the 'go-to' resource for tens of thousands of eye-care professionals around the world. |
| anti-vegf therapy for macular degeneration: Indocyanine Green Angiography Lawrence A. Yannuzzi, Robert W. Flower, Jason S. Slakter, 1997 This is the only text available that is devoted exclusively to the ICG imaging technique, its methods and findings. It provides an invaluable guide to this new diagnostic/research tool. |
| anti-vegf therapy for macular degeneration: Choroidal Disorders Jay Chhablani, Jorge Ruiz-Medrano, 2017-05-31 Choroidal Disorders provides an overview on various chorioretinal disorders with a special emphasis on choroidal imaging. As our understanding of the choroid has significantly improved with the development of advanced optical coherence tomography (OCT) and its role in posterior segment diseases is gaining new significance, this book focuses on the related improvements, diagnostic capabilities, management and prognosis of various chorioretinal disorders. It covers conventional techniques, such as ultrasonography and indocyanine green angiography as well as the most advanced techniques, including enhanced depth imaging OCT, swept source OCT, and OCT angiography. - Concise overview of various chorioretinal disorders, with special emphasis on choroidal imaging - Written for practitioners and researchers in sensory systems (vision), ophthalmologists, and retina specialists - Covers the most advanced imaging techniques in choroidal disorders, such as enhanced depth imaging OCT, swept source OCT, and OCT angiography |
| anti-vegf therapy for macular degeneration: Intraocular Inflammation Manfred Zierhut, Carlos Pavesio, Shigeaki Ohno, Fernando Orefice, Narsing A. Rao, 2016-01-12 This well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease. |
| anti-vegf therapy for macular degeneration: Systematic Reviews University of York. Centre for Reviews and Dissemination, 2009 |
| anti-vegf therapy for macular degeneration: Sample Size Calculations in Clinical Research Shein-Chung Chow, Jun Shao, Hansheng Wang, Yuliya Lokhnygina, 2017-08-15 Praise for the Second Edition: ... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study. -Biometrics This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered ... – Journal of the Royal Statistical Society Sample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation. Features: Compares the relative merits and disadvantages of statistical methods for sample size calculations Explains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages Presents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women’s health Provides sample size calculations for dose response studies, microarray studies, and Bayesian approaches This new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation. |
| anti-vegf therapy for macular degeneration: The Massachusetts Eye and Ear Infirmary Review Manual for Ophthalmology Veeral S. Sheth, Marcus M. Marcet, Paulpoj Chiranand, Harit K. Bhatt, Jeffrey C. Lamkin, Rama D. Jager, 2012-01-05 The new Fourth Edition of the Massachusetts Eye and Ear Infirmary Review Manual for Ophthalmology provides a comprehensive self-assessment review and serves as a valuable study aid for any ophthalmologist or ophthalmologist-in-training. The text contains over 1,500 multiple-choice questions covering the entire field of ophthalmology, including all of its major subspecialties. Answers with explanations are provided for each question, and references are included at the end of each chapter. This edition includes more than 250 new full-color photographs and drawings depicting ocular pathology and ophthalmic conditions. All chapters have been updated with new questions to reflect the latest teaching in the field. A companion website features an interactive test bank with images. The test bank includes all 1,540 questions from the book plus over 300 unique questions for additional self-assessment practice. |
| anti-vegf therapy for macular degeneration: Mononuclear Phagocyte Biology Alvin Volkman, 1984 |
| anti-vegf therapy for macular degeneration: Clinical Applications of Optical Coherence Tomography Angiography Francesco Bandello, Leonardo Mastropasqua, Giuseppe Querques, 2020 The recent introduction of optical coherence tomography angiography (OCTA) has remarkably expanded our knowledge of different retinal, chorioretinal, and optic disc disorders. OCTA is nowadays often introduced as a routine exam in clinical practice, granting the opportunity to non-invasively investigate retinal and choroidal circulation. In this book, many major experts in posterior eye imaging share their experiences and their latest images and ideas about OCTA-- |
| anti-vegf therapy for macular degeneration: Research Methods for Clinical and Health Psychology David F Marks, Lucy Yardley, 2004 The research methods described and illustrated in this book are those particularly useful to the field of clinical and health psychology and cover both qualitative and quantitative approaches. |
| anti-vegf therapy for macular degeneration: Cost-Effectiveness Analysis in Health Peter Muennig, Mark Bounthavong, 2016-02-03 The field's bestselling reference, updated with the latest tools, data, techniques, and the latest recommendations from the Second Panel on Cost-Effectiveness in Health and Medicine Cost-Effectiveness Analysis in Health is a practical introduction to the tools, methods, and procedures used worldwide to perform cost-effective research. Covering every aspect of a complete cost-effectiveness analysis, this book shows you how to find which data you need, where to find it, how to analyze it, and how to prepare a high-quality report for publication. Designed for the classroom or the individual learner, the material is presented in simple and accessible language for those who lack a biostatistics or epidemiology background, and each chapter includes real-world examples and tips and tricks that highlight key information. Exercises throughout allow you to test your understanding with practical application, and the companion website features downloadable data sets for students, as well as lecture slides and a test bank for instructors. This new third edition contains new discussion on meta-analysis and advanced modeling techniques, a long worked example using visual modeling software TreeAge Pro, and updated recommendations from the U.S. Public Health Service's Panel on Cost-Effectiveness in Health and Medicine. This is the second printing of the 3rd Edition, which has been corrected and revised for 2018 to reflect the latest standards and methods. Cost-effectiveness analysis is used to evaluate medical interventions worldwide, in both developed and developing countries. This book provides process-specific instruction in a concise, structured format to give you a robust working knowledge of common methods and techniques. Develop a thoroughly fleshed-out research project Work accurately with costs, probabilities, and models Calculate life expectancy and quality-adjusted life years Prepare your study and your data for publication Comprehensive analysis skills are essential for students seeking careers in public health, medicine, biomedical research, health economics, health policy, and more. Cost-Effectiveness Analysis in Health walks you through the process from a real-world perspective to help you build a skillset that's immediately applicable in the field. |
| anti-vegf therapy for macular degeneration: High Resolution Imaging in Microscopy and Ophthalmology Josef F. Bille, 2019-08-13 This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend. |
| anti-vegf therapy for macular degeneration: Optical Coherence Tomography G. Coscas, A. Loewenstein, F. Bandello, 2014-02-27 Because of its many advantages optical coherence tomography (OCT) has revolutionized the way in which retinal diseases are screened and managed and how treatments are monitored. In this volume the latest developments and findings are presented by experts in their respective fields. After a short introduction covering the available equipment and the basic techniques, the imaging features of various pathological findings in retinal diseases are presented. The topics cover the outer layers including new modalities for choroid imaging, out-layer diseases such as the various types of macular degeneration, retinal diseases such as diabetic retinopathy and vascular occlusion, and retina and vitreous interface pathologies. The final chapters are dedicated to the practicality of using OCT for the pre- and postsurgical evaluation of the posterior segment and for the differential diagnosis of vitreoretinal diseases as well as in the management of patients with retinal and neuro-ophthalmological diseases. Making the essentials of the recently held ESASO course on OCT available in one volume, this publication is a must-read for experienced as well as trainee ophthalmologists who need to use OCT in their daily practice. |
| anti-vegf therapy for macular degeneration: Vitreoretinal Surgery Sandeep Saxena, Carsten H. Meyer, Masahito Ohji, 2012-03-29 The value of this book lies in the quality and expertise of the text chapters contributed by multiple international experts across the globe. Clearly written by the contributors providing a global perspective about the subject. Attempts to update the state-of-the-art vitreoretinal surgery in a lucid, authoritative and well-illustrated manner. Detailed reference lists following each chapter provide extensive background support for the text. Outstanding illustrations combined with excellent schematic drawings, beautiful clinical photographs, fluorescein angiograms, and OCT images. Illustrations. |
| anti-vegf therapy for macular degeneration: Vascular Development Derek J. Chadwick, Jamie A. Goode, 2007-08-20 The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome. |
| anti-vegf therapy for macular degeneration: The Contrast Sensitivity Function: From Laboratory to Clinic Fang Hou, Zhong-Lin Lu, Peter J. Bex, Alexandre Reynaud, 2021-12-30 |
| anti-vegf therapy for macular degeneration: Vaughan & Asbury's General Ophthalmology Paul Riordan-Eva, John P. Whitcher, 2007-11-08 The classic reference covering the diagnosis and treatment of all major ophthalmic diseases, as well as neurological and systemic diseases causing visual disturbance-extensively revised and updated Features State-of-the-art coverage of diagnostic techniques and therapeutic interventions for the full range of ophthalmic disorders Chapters dedicated to ophthalmic therapeutics, neuro-ophthalmology, ocular disorders associated with systemic diseases, immunologic diseases of the eye, pediatrics, genetics, preventive ophthalmology and lasers The latest clinical perspectives on such topics as: Treatments for age-related macular degeneration, including anti-VEGF therapies Intraocular steroid injections for retinal diseases Immunomodulatory drugs Treatment of corneal infections Medical and surgical treatments for glaucoma Detailed appendices on visual standards, practical factors in illumination, rehabilitation of the visually handicapped, and special services available to the blind Latest references |
| anti-vegf therapy for macular degeneration: Handbook of Nutrition, Diet, and the Eye Victor R Preedy, Ronald Ross Watson, 2019-06-11 Handbook of Nutrition, Diet, and the Eye, Second Edition, thoroughly addresses common features and etiological factors on how dietary and nutritional factors affect the eye. The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss are devastating. There are a range of ocular defects that have either their origin in nutritional deficiencies/excess or have been shown to respond favorably to nutritional components. Featuring a new section on animal model studies where both the ocular problem and dietary remedies can be varied, there are also new chapters on dietary supplements. - Serves as a foundational collection for neuroscience, neurology and nutrition researchers, illustrating the importance of nutrition and diet in eye health and function - Provides a common language for readers to discuss how nutritional factors and related diseases and syndromes affect the eye - Features new chapters on infectious diseases of the eye where nutrition is a factor - Discusses animal model studies, dietary supplements, natural dietary extracts from around the world, and age-related changes in ocular health |
| anti-vegf therapy for macular degeneration: The Endothelium Thomas F. Luscher, Paul M. Vanhoutte, 2020-04-15 First published in 1990: The Endothelium: Modulator of Cardiovascular Function takes a comprehensive look at the role of the endothelium in cardiovascular control in health and disease. Experts offer detailed reviews on specific topics that address these roles of the endothelium: diffusion barrier, blood-brain barrier, regulator of capillary permeability, metabolic function (uptake and enzymatic destruction), conversion of vasoactive products, production of prostanoids, production and release of endothelium-derived relaxing factors, production of endothelium-derived contracting factors, production of coagulation factors, production of fibrinolytic factors, reticulo-endothelial function, role in atherosclerosis, and changes in function with aging and disease. This overview provides the reader with an update on the role of one of the most fascinating cells in cardiovascular biology. It focuses on the multiple functions of those cells and offers the first attempt to draw a parallel between these functions. Anyone studying the fields of physiology and pharmacology will benefit from this must have reference resource. |
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Free Virus Scanner | Virus Scan & Removal Software - Avast
Windows Defender lacks many essential features that other free antivirus security solutions provide, such as offline protection and comprehensive anti-phishing defenses. Instead of …
Download Free Antivirus for Windows 10 PCs & Laptops | Avast
I had recommended Avast™ to a co-working friend because he said his computer was running slow. He said he ran the anti-virus …
Download Free Antivirus Software | Avast 2025 PC Protection
While it’ll keep your computer relatively safe against most types of malware, its anti-phishing protection is limited to Microsoft …
Download Free Antivirus Software for Windows 11 | Avast
Strengthen your Windows 11 PC security and protect your entire home Wi-Fi network, plus get advanced tools like anti-malware …
Avast | Download Free Antivirus & VPN | 100% Free & Easy
Join 435 million others and get award-winning free antivirus for PC, Mac & Android. Surf safely & privately with our VPN. …
Avast | Download Free Antivirus & VPN | 100% Free & Easy
Join hundreds of millions of others & get free antivirus for PC, Mac, & Android. Surf safely with our VPN. Download Avast!
