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| areds 2 study results: Making Eye Health a Population Health Imperative National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Population Health and Public Health Practice, Committee on Public Health Approaches to Reduce Vision Impairment and Promote Eye Health, 2017-01-15 The ability to see deeply affects how human beings perceive and interpret the world around them. For most people, eyesight is part of everyday communication, social activities, educational and professional pursuits, the care of others, and the maintenance of personal health, independence, and mobility. Functioning eyes and vision system can reduce an adult's risk of chronic health conditions, death, falls and injuries, social isolation, depression, and other psychological problems. In children, properly maintained eye and vision health contributes to a child's social development, academic achievement, and better health across the lifespan. The public generally recognizes its reliance on sight and fears its loss, but emphasis on eye and vision health, in general, has not been integrated into daily life to the same extent as other health promotion activities, such as teeth brushing; hand washing; physical and mental exercise; and various injury prevention behaviors. A larger population health approach is needed to engage a wide range of stakeholders in coordinated efforts that can sustain the scope of behavior change. The shaping of socioeconomic environments can eventually lead to new social norms that promote eye and vision health. Making Eye Health a Population Health Imperative: Vision for Tomorrow proposes a new population-centered framework to guide action and coordination among various, and sometimes competing, stakeholders in pursuit of improved eye and vision health and health equity in the United States. Building on the momentum of previous public health efforts, this report also introduces a model for action that highlights different levels of prevention activities across a range of stakeholders and provides specific examples of how population health strategies can be translated into cohesive areas for action at federal, state, and local levels. |
| areds 2 study results: What You Must Know About Age-Related Macular Degeneration Jeffrey Anshel, OD, Laura Stevens, MSci, 2018-06-28 Age-related macular degeneration—AMD—is the most commonly diagnosed eye disorder in people over fifty. Well over two million Americans have been told they have AMD, and that number is expected to grow substantially. While this is a frightening statistic, over the last several years, medical researchers have shown that a number of effective treatments can slow, stop, and even reverse the progress of AMD. Now, best-selling authors Dr. Jeffrey Anshel and Laura Stevens, who herself has been diagnosed with this condition, have joined forces to produce an up-to-date guide to what you need to know to combat and even prevent AMD. The book is divided into four parts. Part One explains how the eye works and how AMD develops, in both its wet and its dry forms. It then looks at the most common risk factors and explains how each of these factors negatively affects the structures of the eye. In Part Two, the authors look at the specific nutrients that affect the various cells of the eye. Included is a discussion of AREDS—the National Eye Institute’s study that showed which supplements help protect the eye from disease. Part Three offers an additional weapon against AMD. It explains why diet matters and offers advice on selecting foods that promote eye health while eliminating those that do the most damage. Part Four provides practical suggestions and easy-to-follow tips on how to incorporate this valuable information into your life. If AMD runs in your family or you have been diagnosed with this potentially life-altering condition, it is important to know that there is not only hope, but a real path to a better, healthier life. Knowledge is power, and the more you know, the more likely you are to avoid the consequences of AMD. Let What You Must Know About Age-Related Macular Degeneration help you safeguard one of your most precious gifts—eyesight. |
| areds 2 study results: Webvision Helga Kolb, Eduardo Fernandez, Ralph Nelson, 2007 |
| areds 2 study results: Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease Institute of Medicine, Food and Nutrition Board, Board on Health Sciences Policy, Board on Health Care Services, Committee on Qualification of Biomarkers and Surrogate Endpoints in Chronic Disease, 2010-06-25 Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process. |
| areds 2 study results: Optical Coherence Tomography of Ocular Diseases Joel S. Schuman, James G. Fujimoto, Jay S. Duker, Hiroshi Ishikawa (Professor of ophthalmology and biomedical engineering), Gadi Wollstein, 2022 Optical Coherence Tomography of Ocular Diseases, Fourth Edition covers a range of subjects, from principles and operation techniques to clinical interpretation and the latest innovations in OCT. This book is an essential text for imaging technology. OCT now occupies a dominant role as a diagnostic tool for retinal conditions and glaucoma. At the same time, the technology continues to show potential for emerging clinical and research applications across all the ophthalmological subspecialties. To reflect these rapid advances, this new edition of Optical Coherence Tomography of Ocular Diseases features a complete and thorough revision of the existing text as well as the addition of cutting-edge content to bring this classic resource completely up to date-- |
| areds 2 study results: Comparative Effectiveness Review Methods U. S. Department of Health and Human Services, Agency for Healthcare Research and Quality, 2013-05-17 The Agency for Healthcare Research and Quality (AHRQ) commissioned the RTI International–University of North Carolina at Chapel Hill (RTI-UNC) Evidence-based Practice Center (EPC) to explore how systematic review groups have dealt with clinical heterogeneity and to seek out best practices for addressing clinical heterogeneity in systematic reviews (SRs) and comparative effectiveness reviews (CERs). Such best practices, to the extent they exist, may enable AHRQ's EPCs to address critiques from patients, clinicians, policymakers, and other proponents of health care about the extent to which “average” estimates of the benefits and harms of health care interventions apply to individual patients or to small groups of patients sharing similar characteristics. Such users of reviews often assert that EPC reviews typically focus on broad populations and, as a result, often lack information relevant to patient subgroups that are of particular concern to them. More important, even when EPCs evaluate literature on homogeneous groups, there may be varying individual treatment for no apparent reason, indicating that average treatment effect does not point to the best treatment for any given individual. Thus, the health care community is looking for better ways to develop information that may foster better medical care at a “personal” or “individual” level. To address our charge for this methods project, the EPC set out to answer six key questions (KQ). Key questions for methods report on clinical heterogeneity include: 1. What is clinical heterogeneity? a. How has it been defined by various groups? b. How is it distinct from statistical heterogeneity? c. How does it fit with other issues that have been addressed by the AHRQ Methods Manual for CERs? 2. How have systematic reviews dealt with clinical heterogeneity in the key questions? a. What questions have been asked? b. How have they pre-identified population subgroups with common clinical characteristics that modify their intervention-outcome association? c. What are best practices in key questions and how these subgroups have been identified? 3. How have systematic reviews dealt with clinical heterogeneity in the review process? a. What do guidance documents of various systematic review groups recommend? b. How have EPCs handled clinical heterogeneity in their reviews? c. What are best practices in searching for and interpreting results for particular subgroups with common clinical characteristics that may modify their intervention-outcome association? 4. What are critiques in how systematic reviews handle clinical heterogeneity? a. What are critiques from specific reviews (peer and public) on how EPCs handled clinical heterogeneity? b. What general critiques (in the literature) have been made against how systematic reviews handle clinical heterogeneity? 5. What evidence is there to support how to best address clinical heterogeneity in a systematic review? 6. What questions should an EPC work group on clinical heterogeneity address? Heterogeneity (of any type) in EPC reviews is important because its appearance suggests that included studies differed on one or more dimensions such as patient demographics, study designs, coexisting conditions, or other factors. EPCs then need to clarify for clinical and other audiences, collectively referred to as stakeholders, what are the potential causes of the heterogeneity in their results. This will allow the stakeholders to understand whether and to what degree they can apply this information to their own patients or constituents. Of greatest importance for this project was clinical heterogeneity, which we define as the variation in study population characteristics, coexisting conditions, cointerventions, and outcomes evaluated across studies included in an SR or CER that may influence or modify the magnitude of the intervention measure of effect (e.g., odds ratio, risk ratio, risk difference). |
| areds 2 study results: Principles and Practice of Clinical Research John I. Gallin, Frederick P Ognibene, 2011-04-28 The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.*Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government |
| areds 2 study results: Ryan's Retina E-Book SriniVas R. Sadda, Andrew P. Schachat, Charles P. Wilkinson, David R. Hinton, Peter Wiedemann, K. Bailey Freund, David Sarraf, 2022-04-13 Through six outstanding and award-winning editions, Ryan's Retina has offered unsurpassed coverage of this complex subspecialty—everything from basic science through the latest research, therapeutics, technology, and surgical techniques. The fully revised 7th Edition, edited by Drs. SriniVas R. Sadda, Andrew P. Schachat, Charles P. Wilkinson, David R. Hinton, Peter Wiedemann, K. Bailey Freund, and David Sarraf, continues the tradition of excellence, balancing the latest scientific research and clinical correlations and covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. More than 300 global contributors share their knowledge and expertise to create the most comprehensive reference available on retina today. - Features sweeping content updates, including new insights into the fundamental pathogenic mechanisms of age-related macular degeneration, advances in imaging including OCT angiography and intraoperative OCT, new therapeutics for retinal vascular disease and AMD, novel immune-based therapies for uveitis, and the latest in instrumentation and techniques for vitreo-retinal surgery. - Includes five new chapters covering Artificial Intelligence and Advanced Imaging Analysis, Pachychoroid Disease and Its Association with Polypoidal Choroidal Vasculopathy, Retinal Manifestations of Neurodegeneration, Microbiome and Retinal Disease, and OCT-Angiography. - Includes more than 50 video clips (35 new to this edition) highlighting the latest surgical techniques, imaging guidance, and coverage of complications of vitreoretinal surgery. New videos cover Scleral Inlay for Recurrent Optic Nerve Pit Masculopathy, Trauma with Contact Lens, Recurrent Retinal Detachment due to PVR, Asteroid Hyalosis, and many more. - Contains more than 2,000 high-quality images (700 new to this edition) including anatomical illustrations, clinical and surgical photographs, diagnostic imaging, decision trees, and graphs. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. |
| areds 2 study results: Evidence-Based Ophthalmology Richard Wormald, Katherine Henshaw, Liam Smeeth, 2008-04-30 Evidence-Based Ophthalmology offers a unique approach to managing eye disease. From systematic reviewing of evidence, this book provides an overview of techniques for optimum management in key areas, including glaucoma, cataract and retinal disease – an invaluable reference source for practitioners worldwide representing an important contribution to the literature. Key Features International authorship by leading Cochrane participants An unbiased method for summarising and disseminating the evidence Identifies gaps in evidence, and therefore research opportunities Free-access update website giving the latest trial data and recommendations for implementation in practice Includes a free fully searchable CD-ROM |
| areds 2 study results: Age-Related Macular Degeneration Giuseppe Lo Giudice, 2013-06-12 Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in developed countries.There have been rapid developments of therapies that today can halt or even reverse aspects of vision loss resulting from AMD among those most severely affected, and there is promise of future therapies that may prevent vision loss. This book provides an overview about AMD; an update on the current understanding of AMD, pathophysiology, the use of diagnostic tests, the management of both non-neovascular and neovascular AMD as well as future directions in treatment and its limitations. It also looks into the future with potential treatment options that are now under investigation in clinical trials. |
| areds 2 study results: Age-related Macular Degeneration Diagnosis and Treatment Allen C. Ho, Carl D. Regillo, 2011-08-09 Age-Related Macular Degeneration: Diagnosis and Treatment is written by two leading experts from Wills Eye Hospital. Covering the latest therapies and treatments developed in the last few years, this is a concise yet highly illustrated and practical text that guides the clinician through diagnosis and treatment of the leading cause of blindness in older Americans. |
| areds 2 study results: Anti-Angiogenic Therapy in Ophthalmology Andreas Stahl, 2016-05-13 This book provides a concise overview over the pathology of retinal angiogenic diseases and explains why anti-angiogenic therapy is effective in so many patients. The reader is guided through the various clinical indications for anti-angiogenic therapy and made aware of its merits as well as current challenges and limitations. It is explained how, since its introduction for the treatment of exudative age-related macular degeneration in 2006, anti-angiogenic therapy has revolutionized the way in which we treat a range of ocular diseases. All of the authors are established experts in their respective fields who share their extensive knowledge and clinical experience with the reader. This book is both a valuable introduction to anti-angiogenic therapy in ophthalmology and a day-to-day companion for all ophthalmologists seeing patients with some of the most prevalent retinal diseases. |
| areds 2 study results: Intraocular Inflammation Manfred Zierhut, Carlos Pavesio, Shigeaki Ohno, Fernando Orefice, Narsing A. Rao, 2016-01-12 This well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease. |
| areds 2 study results: Carotenoids in Health and Disease Norman I. Krinsky, Susan T. Mayne, Helmut Sies, 2004-08-30 The first source to collect the latest evidence linking carotenoids to human health and disease, this stimulating reference studies the role of carotenoids in the prevention of chronic disease and reviews breakthrough studies from more than 40 field authorities on the latest research. The book reveals the most recent findings regarding the use of c |
| areds 2 study results: 50 Studies Every Ophthalmologist Should Know Alan Penman, Kimberley Crowder, Michael E. Hochman, William M. Watkins, 2020 50 Studies Every Ophthalmologist Should Know presents key studies that have shaped the practice of ophthalmology. Selected using a rigorous methodology, emphasis has been placed on landmark studies which have influenced current ophthalmology practice guidelines. This book is a must-read for ophthalmologists, especially those in training or preparing for board review, as well as anyone who wants to learn more about the data behind clinical practice. |
| areds 2 study results: The Contrast Sensitivity Function: From Laboratory to Clinic Fang Hou, Zhong-Lin Lu, Peter J. Bex, Alexandre Reynaud, 2021-12-30 |
| areds 2 study results: Manual of Retinal Diseases Carlos A. Medina, Justin H. Townsend, Arun D. Singh, 2016-04-26 This book is a comprehensive source of authoritative information on the clinical features,diagnosis, differential diagnosis, and management of medical and surgical retinal diseases. The Manual has 122 chapters, organized in 18 sections covering medical and surgical aspects of retinal diseases such as trauma, AMD, Uveitis, infections, endophthalmitis, pediatric diseases, dystrophies, and tumors. Easy-to-read chapters convey the fundamental concepts with the aid of clinical photographs, imaging studies (including fluorescein and indocyanine angiograms, ultrasonograms, CT scans, and MRI scans) and tables. The manual is of value to a wide range of practitioners and trainees, including students,residents, fellows and ophthalmologists who treat retinal diseases. |
| areds 2 study results: Exploring Ethical Problems in Todays Technological World Fudge, Tamara Phillips, 2022-06-30 The pervasiveness of technology today has brought with it a bevy of ethical questions, many of which are difficult to answer. Average consumers place themselves at risk financially, professionally, and personally by everyday activities executed on computers and smartphones, and therein lies the responsibility of technologists and decision-makers to devise logical and ethical solutions. Exploring Ethical Problems in Todays Technological World focuses on ethical dilemmas created by today's ever-changing technologies and how these issues have affected individuals, companies, and society. The book further explores key areas such as policies, abuses, consequences, and responsibilities of different technologies and their users. Covering topics such as hackers, smart homes, privacy, and social networking, this reference work is ideal for ethicists, computer scientists, policymakers, industry professionals, researchers, academicians, practitioners, and students studying ethics, law, security, human-computer interaction, and computer science. |
| areds 2 study results: Integrative Medicine, eBook David P. Rakel, Vincent Minichiello, 2022-08-12 Written by physicians who are experts in both traditional and complementary medicine, Integrative Medicine, 5th Edition, uses a clinical, disease-oriented approach to safely and effectively incorporate alternative therapies into primary care practice. Drawing on available scientific evidence and the authors' first-hand experiences, it covers therapies such as botanicals, supplements, mind-body, lifestyle choices, nutrition, exercise, spirituality, and other integrative medicine modalities. This highly regarded reference offers practical guidance for reducing costs and improving patient care while focusing on prevention and wellness for a better quality of life. - Explains how to make the best use of integrative medicine and the mechanisms by which these therapeutic modalities work, keeping you at the forefront of the trend toward integrative health care. - Templated chapters make it quick and easy to find key information such as dosing, pearls, the Prevention Prescription, and Therapeutic Reviews that incorporates the Evidence vs Harm Icon. - Uses the reliable SORT method (Strength of Recommendation Taxonomy) to provide evidence-based ratings, grading both the evidence and the relative potential harm. - Thoroughly updated, ensuring that you remain well informed regarding the latest evidence. - Contains 10 new chapters covering clinician resilience, supporting immunity, NASH/fatty liver, hair loss, rethinking the movement prescription, compassion practices, prescribing low-dose naltrexone, psychedelics, tapering off PPIs and opioids, as well as an expanded osteopathy chapter. - Covers timely topics aimed at reducing the epidemics of polypharmacy and opioid overuse, as well as supporting immunity in the face of infectious diseases. - Provides online access to multiple-choice questions for every chapter—perfect for board exam review. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. |
| areds 2 study results: Fundus Autofluorescence Noemi Lois, John V. Forrester, 2012-02-13 Featuring over 250 illustrations, this detailed full-color textbook provides up-to-date information on the use of fundus autofluorescence imaging in evaluation of retinal disease. Chapters describe the techniques available to image and quantify fundus autofluorescence and the autofluorescence patterns observed in the healthy eye and in various retinal diseases. Emphasis is on the value of fundus autofluorescence as a diagnostic and prognostic tool and its clinical utility in the context of other imaging techniques, such as fluorescein and indocyanine green angiography and optical coherence tomography. Each chapter also discusses the value of fundus autofluorescence in understanding the pathogenesis of the condition, and provides a comprehensive update on all aspects of the condition. A companion Website will offer the fully searchable text and an image bank. |
| areds 2 study results: Handbook of Nutrition, Diet, and the Eye Victor R Preedy, Ronald Ross Watson, 2019-06-11 Handbook of Nutrition, Diet, and the Eye, Second Edition, thoroughly addresses common features and etiological factors on how dietary and nutritional factors affect the eye. The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss are devastating. There are a range of ocular defects that have either their origin in nutritional deficiencies/excess or have been shown to respond favorably to nutritional components. Featuring a new section on animal model studies where both the ocular problem and dietary remedies can be varied, there are also new chapters on dietary supplements. - Serves as a foundational collection for neuroscience, neurology and nutrition researchers, illustrating the importance of nutrition and diet in eye health and function - Provides a common language for readers to discuss how nutritional factors and related diseases and syndromes affect the eye - Features new chapters on infectious diseases of the eye where nutrition is a factor - Discusses animal model studies, dietary supplements, natural dietary extracts from around the world, and age-related changes in ocular health |
| areds 2 study results: 50 Studies Every Ophthalmologist Should Know Alan Penman, Kimberley Crowder, William M. Watkins, 2020-04-21 50 Studies Every Ophthalmologist Should Know presents key studies that have shaped the practice of ophthalmology. Selected using a rigorous methodology, emphasis has been placed on landmark studies which have influenced current ophthalmology practice guidelines. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for ophthalmologists, especially those in training or preparing for board review, as well as anyone who wants to learn more about the data behind clinical practice. |
| areds 2 study results: Age-Related Macular Degeneration, Third Edition Jennifer I. Lim, 2012-11-15 The value of Age-Related Macular Degeneration has stood the test of time, but progress in both basic and clinical ophthalmology has been relentless, mandating the need for an updated book. This second edition focuses on the pathophysiology and the epidemiology of age-related macular degeneration (AMD), the clinical features and management of dry an |
| areds 2 study results: The Atlas of Retinal Diseases in Nigerians S. Tunji, 2020-09-21 The Atlas of Retinal Diseases in Nigerians is an attempt to document common retinal diseases seen by the author over the past 20 years. The book is intended to be a quick reference guide for ophthalmologist-in-training and to offer brief management modalities based on evidence in the literature. Some major landmark retinal studies are summarized to help in decision-making based on scientific evidence. A section on the use of mobile phones for taking retinal pictures is included to aid patient education and telemedicine. Finally, retinal studies by the author carried out on Nigerians is summarized at the end of the book. |
| areds 2 study results: Eat Right for Your Sight Jennifer Trainer Thompson, Johanna M. Seddon, 2015-02-24 Safeguard your vision with 85 simple, satisfying recipes rich in the nutrients that fight macular degeneration The Bad News: Age-related macular degeneration (AMD) is the leading cause of central vision loss in adults over the age of fifty. It can wreak havoc on the ability to see faces, read, drive, and move about safely. Millions of people are at risk, and we still don’t have a cure. The Good News: The latest research suggests that healthy lifestyle choices, including a diet rich in lutein, zeaxanthin, and other key nutrients, can delay the onset and progress of AMD. Eat Right for Your Sight provides a delicious way to add the best ingredients for eye health to every meal of the day. Feast your eyes on these appealing recipes: Sweet Pea Guacamole Chicken-Vegetable Noodle Bowls Garlic-Lime Pork Chops Carrot-Ginger Juice . . . and more! Every recipe includes comprehensive nutrition information and has been carefully crafted to act like medicine but not taste like it. Taking care of your eyes has never been easier! With Recipes from Lidia Bastianich, Ina Garten, Jacques Pépin , Alice Waters, Andrew Weil, MD, and other superstars of healthy cooking. |
| areds 2 study results: Retina Stephen J. Ryan, 2013 Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia the Americas.Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard.Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. |
| areds 2 study results: Advances in Food and Nutrition Research Fidel Toldra, 2020-07-23 Advances in Food and Nutrition Research, Volume 93, provides information on nutrients in foods and how to avoid their deficiency, especially for those essential nutrients that should be present in the diet. Specific topics covered in this new release include drying, a relevant unit operation in the manufacture of foods and nutritional products, polycyclic aromatic hydrocarbons in edible oils and fatty foods, including occurrence, formation, analysis, change, and control, food allergens and their characterization, molecular properties and clinical implications, the design, quality, safety and efficacy of extensively hydrolyzed formula for the management of cow's milk protein allergy, and much more. The series provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits, as well as up-to-date information on food science, including raw materials, production, processing, distribution and consumption. - Contains contributions that have been carefully selected based on their vast experience and expertise on the subject - Includes updated, in-depth and critical discussions of available information, giving the reader a unique opportunity to learn - Encompasses a broad view of the topics at hand |
| areds 2 study results: Artificial Intelligence in Ophthalmology Andrzej Grzybowski, 2021-10-13 This book provides a wide-ranging overview of artificial intelligence (AI), machine learning (ML) and deep learning (DL) algorithms in ophthalmology. Expertly written chapters examine AI in age-related macular degeneration, glaucoma, retinopathy of prematurity and diabetic retinopathy screening. AI perspectives, systems and limitations are all carefully assessed throughout the book as well as the technical aspects of DL systems for retinal diseases including the application of Google DeepMind, the Singapore algorithm, and the Johns Hopkins algorithm. Artificial Intelligence in Ophthalmology meets the need for a resource that reviews the benefits and pitfalls of AI, ML and DL in ophthalmology. Ophthalmologists, optometrists, eye-care workers, neurologists, cardiologists, internal medicine specialists, AI engineers and IT specialists with an interest in how AI can help with early diagnosis and monitoring treatment in ophthalmic patients will find this book to be an indispensable guide to an evolving area of healthcare technology. |
| areds 2 study results: Principles and Practice of Ophthalmology E-Book Daniel M. Albert, Joan W. Miller, Dimitri T. Azar, Barbara A. Blodi, 2008-02-27 Inside the 3rd edition of this esteemed masterwork, hundreds of the most distinguished authorities from around the world provide today's best answers to every question that arises in your practice. They deliver in-depth guidance on new diagnostic approaches, operative technique, and treatment option, as well as cogent explanations of every new scientific concept and its clinical importance. With its new streamlined, more user-friendly, full-color format, this 3rd edition makes reference much faster, easier, and more versatile. More than ever, it's the source you need to efficiently and confidently overcome any clinical challenge you may face. Comprehensive, authoritative, and richly illustrated coverage of every scientific and clinical principle in ophthalmology ensures that you will always be able to find the guidance you need to diagnose and manage your patients' ocular problems and meet today's standards of care. Updates include completely new sections on Refractive Surgery and Ethics and Professionalism... an updated and expanded Geneitcs section... an updated Retina section featuring OCT imaging and new drug therapies for macular degeneration... and many other important new developments that affect your patient care. A streamlined format and a new, more user-friendly full-color design - with many at-a-glance summary tables, algorithms, boxes, diagrams, and thousands of phenomenal color illustrations - allows you to locate the assistance you need more rapidly than ever. |
| areds 2 study results: Albert and Jakobiec's Principles and Practice of Ophthalmology Daniel M. Albert, Joan W. Miller, Dimitri T. Azar, Lucy H. Young, 2022-04-07 Keeping up to date with advances in comprehensive ophthalmology and in the ophthalmic sub-specialties is extremely difficult because of the accelerating rapidity with which new information and technology become available and the diminishing time and opportunity for practitioners and trainees to read and learn. The first edition of Albert and Jakobiec’s Principles and Practice (1994) was conceived with the idea of utilizing an electronic, updated version in which the chapters were revised by the chapter authors on an annual or semi-annual basis, but the technology was not sufficiently advanced to achieve this goal. Subsequent editions (2000 and 2008) were organized by Saunders and the last published by Elsevier (of which Springer has obtained the complete rights to move forward with the 4th edition, see attachment). For nearly three decades, this text has provided its readers with authoritative and comprehensive coverage of clinical ophthalmology, written and edited by a group of authors who represented a “Who’s Who” in ophthalmology. By using Springer’s Meteor platform, with its ability to allow authors and editors access to updating their chapters online annually/semi-annually, and with the recruitment of select chapter authors, this work’s usefulness as the standard text in ophthalmology will be maintained and expanded upon by Springer. The 4th edition of this comprehensive and authoritative text is written by hundreds of the most distinguished authorities from around the world and edited by four leaders in the field, providing today's best answers to every question that arises in ophthalmology practice. Richly illustrated with thousands of high quality, full color, clinically-relevant images, Albert and Jakobiec's Principles and Practice of Ophthalmology, 4th Edition covers every scientific and clinical principle in ophthalmology, ensuring that the reader will always be able to find the guidance needed to diagnose and manage patients' ocular problems and meet today's standards of care. Written for practicing ophthalmologists and trainees, this book delivers in-depth guidance on new diagnostic approaches, operative techniques, and treatment options, as well as coherent explanations of new scientific concept and its clinical importance. The 4th edition will prove to be the source every practicing clinician needs to efficiently and confidently overcome any clinical challenge they may face. Updates include new chapters on anterior and posterior segment diseases, as well as chapters more focused on treatment, plus thousands of new, high-quality, color images and illustrations, updated references, and information on the most cutting-edge technology used by clinicians in their practices today. Additionally, readers will enjoy the same, user-friendly, full-color design they remember from the previous edition, complete with many at-a-glance summary tables, algorithms, boxes, and diagrams that allow the reader to locate the assistance needed more rapidly than ever. |
| areds 2 study results: The Columbia Guide to Basic Elements of Eye Care Daniel S. Casper, George A. Cioffi, 2019-07-01 This unique resource is a practical, easy-to-use guide for the non-ophthalmologist healthcare provider as they encounter patients with eye complaints and other concerning ophthalmic conditions. The Columbia Guide to Basic Elements of Eye Care is specifically designed with the non-ophthalmologist in mind, and provides a foundation of basic eye anatomy and physiology, functional analysis, pathology, and concepts in eye care. Each chapter delivers an accessible summary of various ophthalmic diseases and conditions, all of which are frequently encountered in everyday practice. These chapters provide in-depth discussions on a wide range of topics, from testing and examination procedures to management protocols, referral guidelines and expected frequency of follow-up for each disorder. Complete with hundreds of high-quality, descriptive illustrations and clinical photographs, The Columbia Guide to Basic Elements of Eye Care presents clear, understandable explanations of basic eye anatomy, physiology, disease and treatment for non-ophthalmic practitioners and students. In doing so, this guide provides a framework for determining the normal versus the abnormal, helping the reader recognize which patients require referral, and identify which conditions are developing, require urgent treatment, or can be routinely followed. Non-ophthalmologist healthcare providers and students alike will find this book, written by leaders in the field, a practical resource to consult as they encounter patients with treatable but potentially sight-threatening conditions. |
| areds 2 study results: Fundamentals of Geriatric Pharmacotherapy Lisa C. Hutchison, Rebecca B. Sleeper, 2015-03-01 As the number of older patients surge, so too will the medication management challenges pharmacists and other healthcare providers face with this population. Providing care for these often complex cases means not only staying on top of new medications and therapies, but dealing with a wide range of other issues as well. Now in its second edition, Fundamentals of Geriatric Pharmacotherapy, by Lisa C. Hutchison and Rebecca B. Sleeper, offers the full support you need to provide the most effective medication management and therapeutic decisions. This text is unique, not only as a comprehensive overview of major issues in geriatric pharmacotherapy and a core textbook for students, but as a resource for all healthcare professionals who treat elderly patients. Covering all major topics and issues, the second edition provides the most current information and proven strategies in one comprehensive guide, including associated issues that impact therapy, such as the coordination of care across multiple venues and caregivers. Inside this edition, you will find: Summarized treatment guidelines Evidence-based reviews Recommendations for the frail elderly Case studies and clinical pearls Key points, terms, and definitions Self-assessment questions Extensively referenced New chapters on Palliative and Hospice Care and Infections and Antimicrobial Stewardship The demands of an aging population mean that a greater understanding of geriatric pharmacotherapy is now essential for all healthcare providers. Written by practicing geriatric specialists, Fundamentals of Geriatric Pharmacotherapy provides all the detailed information and practical guidance you need. |
| areds 2 study results: Current Clinical Evidence in Ophthalmology H.W. Roberts, J. Gale, K.R. Martin, 2017-04-26 Do you always have the latest evidence based medicine at your fingertips? The book is accompanied by the website www.evidence-ophthalmology.com which contains all the trials featured in the book and will be updated with data as it becomes available. The website also provides opportunities for active discussions through comment sections for each trial. Complimentary access to the website is provided when purchasing the book. 'Current Clinical Evidence in Ophthalmology' summarizes 77 important landmark trials in ophthalmology. Written in a concise and logical format, the book is designed to be both an aide-memoire for the busy clinician and a textbook for ophthalmology trainees sitting specialist examinations. Users will find this book with accompanying website to be a valuable resource in an easily accessible and portable format. Important studies have been featured on topics including: Age-related macular degeneration Amblyopia Angle closure glaucoma Cataract surgery Diabetic retinopathy and maculopathy Herpetic eye disease Idiopathic intracranial hypertension Keratoconus Ocular hypertension Optic neuritis Primary open angle glaucoma Retinopathy of prematurity Retinal vein occlusion Vitreomacular traction and others |
| areds 2 study results: ClinicalTrials Curtis L. Meinert, 2012-03-27 The classic, definitive guide to the design, conduct, and analysis of randomized clinical trials. |
| areds 2 study results: Ryan's Retina E-Book Charles P. Wilkinson, David R. Hinton, SriniVas R. Sadda, Peter Wiedemann, 2017-04-17 The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology. |
| areds 2 study results: Evidence-based Eye Care Peter J. Kertes, Thomas Mark Johnson, 2007 This volume offers every clinical ophthalmologist valuable guidance in implementing the results of the latest multicenter clinical trials in practice. Chapters on all major disease entities review all pertinent trials, bring these trials into a real-world setting, and show how the results should influence day-to-day patient management. Coverage includes diseases in all ophthalmologic subspecialties—cornea/external disease, glaucoma, retina, pediatric ophthalmology, ocular oncology, neuro-ophthalmology, and oculoplastics. More than 170 illustrations, 92 in full color, complement the text. General ophthalmologists will have at their fingertips, in an easily digestible format, the current standard of patient care across the spectrum of ophthalmology. |
| areds 2 study results: Lipids Claude Leray, 2014-11-05 The role of lipids in nutrition science has evolved considerably in the past decade with new concepts following new discoveries. Lipids: Nutrition and Health reviews the role of dietary lipids in maintaining health, bringing the latest knowledge from a myriad of sources into one convenient resource. Taking a combined approach that integrates lipid nutrition with normal physiology and clinical applications, the book presents a detailed account of the nutritional aspects of all types of lipids—fatty acids, triacylglycerols, phospholipids, sphingolipids, sterols, and fat-soluble vitamins (A, D, E, K). The book introduces the biochemistry and sources of lipid compounds, followed by coverage of lipid requirements for a healthy state. Organized by lipid category, the text describes the role played by each lipid in various chronic diseases. It examines specific macronutrients and micronutrients, emphasizing their absorption, metabolism, and deficiency symptoms with respect to their roles in cardiovascular disease, cancer, metabolic diseases, inflammatory diseases, and various pathologies of the nervous system. Offering a broad overview of all aspects of lipids, from the fatty acids to the other forms of fats, the book provides an extensive and up-to-date survey of the impact of dietary lipids on various aspects of pathological situations. It provides the information needed to efficiently translate new research findings and clinical experiences into practical and personalized recommendations for preventing diseases and treating pathologies induced by poor dietary conditions. |
| areds 2 study results: Age-Related Macular Degeneration Weiye Li, 2021-03-23 A consolidated view of a complex disorder, Age-Related Macular Degeneration, summarizes the latest evidence-based studies and translates these advancements into practical, actionable knowledge. This concise resource covers the fundamentals of age-related macular degeneration (AMD) diagnosis and treatment along with a modern definition of the disorder that acknowledges the range of presentations that ophthalmologists see in real practice. Offering practical, clinical guidance in addition to capturing new therapeutic approaches in the pipeline, this book is an essential reference for ophthalmologists, optometrists, and researchers. - Takes a concise, yet comprehensive, approach to AMD, covering both basic science and clinical guidance. - Features clinical guidelines on the diagnosis and treatment of AMD, including classification, signs/symptoms, imaging, and differential diagnosis in the pre-optical coherence tomography (OCT) and modern OCT eras. - Presents up-to-date information on AMD therapies currently in the development pipeline and offers insights for the future of translational research. - Explains molecular genetics and pathogenic events of AMD from both basic and clinical perspectives, which may help readers seek promising new therapeutic targets - Contains more than 250 images, with multimodal imaging techniques that clearly demonstrate AMD pathophysiology and clinical pathology. |
| areds 2 study results: Novel Therapeutic Approaches for the Treatment of Ocular Disease, Volume I Kyriaki Thermos, Stephanie C. Joachim, Deniz Hos, Giovanni Casini, 2022-07-27 |
| areds 2 study results: Preventive Nutrition Adrianne Bendich, Richard J. Deckelbaum, 2009-10-03 Evidence-based nutritional interventions are now a critical component of preventive medicine, employed in a wide variety of medical scenarios. Preventive Nutrition: A Comprehensive Guide for Health Professionals, Fourth Edition gives health professionals up-to-date, comprehensive reviews that evaluate the dietary practices and interventions that have been shown to reduce disease risk and improve health outcomes. This is the flagship volume for the book series, Nutrition and Health, which has become an essential tool for health professionals. As the state of global health and nutrition have changed much since the publication of the Third Edition, this major revised and expanded Fourth Edition includes newly authored chapters and features analysis of the results of the Women’s Health Initiative, the largest intervention study ever undertaken and completed in postmenopausal women. Other new material includes chapters reviewing the evidence concerning econutrition, micronutrients and major cancers, and cognitive function and other mental health areas. Also discussed are the importance of gastric acid secretions, the nutritional effects of current therapies, and the latest information on the biology of obesity and its relationship to Type 2 diabetes. One key new feature of this edition is a chapter on behavioral strategies to help assure compliance with dietary regimes, maximizing the health benefits of preventive nutrition. The authors have created the most comprehensive and up-to-date review of the nutritional strategies available for the prevention of disease and the promotion of health through nutrition. Patients are looking for credible information from their health care providers about a whole range of subjects covered here, including ß-carotene, lycopene, antioxidants, folate, and the myriad of bioactive phytochemicals found in garlic and other foods. With sections on cardiovascular disease, diabetes, and pregnancy among many others, this volume will be of great value to practicing health professionals, including physicians, nutritionists, dentists, pharmacists, dieticians, health educators, policy makers, health economists, regulatory agencies and research investigators. An entire section covers nutrition transitions around the world including Eastern Europe, Latin America and Asia as well as goals for preventive nutrition in developing countries. |
Age-Related Eye Disease Studies (AREDS/AREDS2)
Dec 27, 2024 · The Age-Related Eye Disease Study (AREDS) and AREDS2 are major clinical trials sponsored by the National Eye Institute. The AREDS studies were designed to learn …
AREDS2 10-Year Follow-up of AMD Progression - JAMA Network
Jun 2, 2022 · In 2001, the Age-Related Eye Diseases Study (AREDS) Research Group demonstrated the effectiveness of the AREDS supplement of antioxidant vitamins and zinc …
The Age-Related Eye Disease Study 2 (AREDS2): Study Design …
The primary purpose of Age-Related Eye Disease Study 2 (AREDS2) is to evaluate the efficacy and safety of lutein+zeaxanthin (L+Z) and/or omega-3 long-chain polyunsaturated fatty acid …
The AREDS2 10-year Follow-on Study: At 10 Years, the …
The newly published AREDS2 10-year follow-on study data assessed the long-term effects of replacing beta-carotene with L/Z in the original AREDS supplement and tracked the nutrients’ …
Long-Term Outcomes of Revised AREDS2 Supplement
Aug 1, 2022 · In this follow-up study, all participants received the AREDS2 supplements that had no beta carotene but did have lutein/zeaxanthin, vitamins C and E, and zinc plus copper. …
What is the AREDS 2 Study?
The AREDS 2 study results showed that omitting beta-carotene and adding lutein and zeaxanthin to the original AREDS formula reduced the risk of progression of AMD by 18% compared to …
The Age-related Eye Disease Study 2 (AREDS2) - Ophthalmology
Jul 29, 2011 · The primary purpose of the Age-Related Eye Disease Study 2 (AREDS2) is to evaluate the efficacy and safety of lutein plus zeaxanthin (L+Z) and/or ω-3 long-chain …
AREDS/AREDS2 Clinical Trials - National Eye Institute
Dec 3, 2024 · AREDS included 4,757 participants, ages 55-80 years, with cataract, AMD, or both. AMD results are based on 3,640 participants who had early or worse AMD. Cataract results …
The Results of the 10 Year Follow-on Study of the Age-Related …
Methods : The AREDS2 clinical trial randomly assigned participants with bilateral intermediate AMD or late AMD in one eye to lutein/zeaxanthin and/or omega-3 fatty acids or placebo. …
The Age-Related Eye Disease 2 Study: Micronutrients in the Treatment of ...
Initial results from the Age-Related Eye Disease Study (AREDS) indicated that supplementation with antioxidants (β-carotene and vitamins C and E) and zinc was associated with a reduced …
Age-Related Eye Disease Studies (AREDS/AREDS2)
Dec 27, 2024 · The Age-Related Eye Disease Study (AREDS) and AREDS2 are major clinical trials sponsored by the National Eye Institute. The AREDS studies were designed to learn …
AREDS2 10-Year Follow-up of AMD Progression - JAMA Network
Jun 2, 2022 · In 2001, the Age-Related Eye Diseases Study (AREDS) Research Group demonstrated the effectiveness of the AREDS supplement of antioxidant vitamins and zinc with …
The Age-Related Eye Disease Study 2 (AREDS2): Study Design …
The primary purpose of Age-Related Eye Disease Study 2 (AREDS2) is to evaluate the efficacy and safety of lutein+zeaxanthin (L+Z) and/or omega-3 long-chain polyunsaturated fatty acid …
The AREDS2 10-year Follow-on Study: At 10 Years, the …
The newly published AREDS2 10-year follow-on study data assessed the long-term effects of replacing beta-carotene with L/Z in the original AREDS supplement and tracked the nutrients’ …
Long-Term Outcomes of Revised AREDS2 Supplement
Aug 1, 2022 · In this follow-up study, all participants received the AREDS2 supplements that had no beta carotene but did have lutein/zeaxanthin, vitamins C and E, and zinc plus copper. …
What is the AREDS 2 Study?
The AREDS 2 study results showed that omitting beta-carotene and adding lutein and zeaxanthin to the original AREDS formula reduced the risk of progression of AMD by 18% compared to the …
The Age-related Eye Disease Study 2 (AREDS2) - Ophthalmology
Jul 29, 2011 · The primary purpose of the Age-Related Eye Disease Study 2 (AREDS2) is to evaluate the efficacy and safety of lutein plus zeaxanthin (L+Z) and/or ω-3 long-chain …
AREDS/AREDS2 Clinical Trials - National Eye Institute
Dec 3, 2024 · AREDS included 4,757 participants, ages 55-80 years, with cataract, AMD, or both. AMD results are based on 3,640 participants who had early or worse AMD. Cataract results …
The Results of the 10 Year Follow-on Study of the Age-Related …
Methods : The AREDS2 clinical trial randomly assigned participants with bilateral intermediate AMD or late AMD in one eye to lutein/zeaxanthin and/or omega-3 fatty acids or placebo. …
The Age-Related Eye Disease 2 Study: Micronutrients in the Treatment of ...
Initial results from the Age-Related Eye Disease Study (AREDS) indicated that supplementation with antioxidants (β-carotene and vitamins C and E) and zinc was associated with a reduced …
