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| beats electronics co-founder: Summary of Tripp Mickle’s After Steve Milkyway Media, 2023-01-03 Buy now to get the main key ideas from Tripp Mickle’s After Steve What happens when a company loses a driving force like Steve Jobs? In After Steve (2022), Tripp Mickle lays out the internal and external struggles Apple faced after its iconic founder’s death. It seemed that all was well: chief designer Jony Ive continued to create exquisite designs, and they were backed by new CEO Tim Cook's deft ability to maximize sales. Apple developed indispensable products and services like Apple Watch, Apple Music, Apple Pay, and more, becoming America's first trillion-dollar company. However, the constant demand for new revolutionary products, combined with Cook’s tendency to favor speed over substance, pushed Apple away from its innovative roots and drove its creative soul, Ive, out of the company. |
| beats electronics co-founder: Origins of a Song Jake Grogan, 2018-05-01 David Bowie, tired of the rock 'n roll Los Angeles lifestyle, picks up and moves to West Berlin. Sixteen-year-old Rod Stewart sneaks into a music festival and has a coming-of-age experience. Paul McCartney dreams of his deceased mother. The rest is music history. For lyricists and listeners alike, Origins of a Song is the inspiring collection of 202 true stories behind the world’s greatest lyrics. Delve into the compelling real-life stories behind the world’s greatest lyrics with Origins of a Song. Featuring profiles of 202 musical masterpieces that span genres and generations, this book explores the inspiration and creative process behind each song. Get glimpses into the inception of these timeless tunes, and learn about the individual creative process for these songwriters and musicians. Origins of a Song will not only leave you with a different perspective on your favorite songs, but it will also have you inspired to start crafting some yourself! Author Jake Grogan is originally from Ellenville, New York, and currently resides in Queens. He has a BA from Fordham University, where he studied journalism. The story behind his favorite song, Dancing Queen by ABBA, inspired him to pursue Origins of a Song. |
| beats electronics co-founder: American Popular Music and Its Business in the Digital Age Rick Sanjek, 2024-07-19 American Popular Music and Its Business in the Digital Age: 1985-2020 by Rick Sanjek is the sequel to his father Russell Sanjek's American Popular Music and Its Business: the First 400 Years. This book offers a detailed and objective history of the popular music industry from the introduction of the compact disc to the shift to streaming, with particular emphasis on the creators, the consumers, and the music business professionals who, in Sanjek's telling, form the three major axes of the industry. Each of the book's three sections--1985-1995, 1996-2006, and 2007-2019--has five chapters covering the same areas and issues. The first chapter in each section outlines the competition between the Big Six music conglomerates, their corporate structures, leadership, finances, and market share. The second chapter traces the synergy between the labels, the retail sector, radio, and the trade magazines whose charts are the pacemaker for the entire industry. Third comes music publishing, licensing, copyright, and legal issues including legislation, litigation, and infringement, followed by a focus on creators and how they earn their money. Each final chapter examines how, how much, and where consumers--who lead in adopting new technology--spend their money. Underlying it all is an insider's perspective on the role that the CD, Napster, Apple, Spotify, YouTube, SoundScan, electronic ticketing, and other innovations had in redefining the business structure and revenue flow of the entire industry. Digital technology also affected the regulations, contracts, and financial transactions that define the complex business of music, as live performance transitioned from clubs, concert halls, and theaters to arenas, amphitheaters, and stadiums. Concurrently, recorded music evolved from analog to digital sound carriers through MP3 downloads and then to on-demand streaming files, ultimately affecting consumers, creators, and the music business infrastructure that connects them. Finally, an epilogue includes the effects of COVID-19 in 2020 on all involved, closing with a glimpse into the digital future with the emergence of TikTok, livestreaming, immersive media, and artificial intelligence. |
| beats electronics co-founder: Lessons Learned from Popular Culture Tim Delaney, Tim Madigan, 2016-06-28 Informative and entertaining introduction to the study of popular culture. As the culture of the people, popular culture provides a sense of identity that binds individuals to the greater society and unites the masses on ideals of acceptable forms of behavior. Lessons Learned from Popular Culture offers an informative and entertaining look at the social relevance of popular culture. Focusing on a wide range of topics, including film, television, social media, music, radio, cartoons and comics, books, fashion, celebrities, sports, and virtual reality, Tim Delaney and Tim Madigan demonstrate how popular culture, in contrast to folk or high culture, gives individuals an opportunity to impact, modify, or even change prevailing sentiments and norms of behavior. For each topic, they include six engaging and accessible stories that conclude with short life lessons. Whether youre a fan of The Big Bang Theory or Seinfeld, the Beatles or Beyoncé, Charlie Brown or Superman, theres something for everyone. |
| beats electronics co-founder: Global Media Giants Benjamin Birkinbine, Rodrigo Gomez, Janet Wasko, 2016-07-01 Global Media Giants takes an in-depth look at how media corporate power works globally, regionally, and nationally, investigating the ways in which the largest and most powerful media corporations in the world wield power. Case studies examine not only some of the largest media corporations (News Corp., The Microsoft Corporation) in terms of revenues, but also media corporations that hold considerable power within national, regional, or geolinguistic contexts (Televisa, The Bertelsmann Group, Sony Corporation). Each chapter approaches a different corporation through the lens of economy, politics, and culture, giving students and scholars a thoughtful and data-driven guide with which to interrogate contemporary media industry power. |
| beats electronics co-founder: Billboard , 2009-10-24 In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends. |
| beats electronics co-founder: The Dna of African Diaspora Sebastian Joseph, 2022-07-19 What image comes to your mind when you think of Africa? A group of insecure and none developing emerging countries? Have you ever wondered if you can safely return from Africa if you go to Africa? The land of thieves and murderers? Haven't you heard so many? If this is how you feel in your mind, the advertisement of those who have been looting Africa for more than five hundred years has been successful. But how many of you know until today that over 60% of the natural resources and precious metals such as Diamond, Gold, Platinum, Silver, Zinc, Lead, Sulphur, Phosphate, Bauxite, Nickel, Copper, Iron, Tantalite, Tin, Uranium, Limestone, Oil & Gas, Coal and many more are exported officially or looted from Africa to Europe, United States, China, United Kingdom, Russia, Asia and more such leading countries? How many of you know Cocoa, the raw material for most of the chocolate we eat, is 80% produced in Africa? Some 67 million tourists visited Africa in 2018, representing a rise of 7% from a year earlier, making Africa the second-fastest-growing region for tourism after the Asia Pacific. To the best of your knowledge, have you ever heard of these tourists being harassed or killed by any Africans or even African wild animals? This is just one example of who is behind the scandal surrounding Africa. As you read this book, you will find more evidence that the African continent is feeding on the big countries mentioned above. |
| beats electronics co-founder: Mass Communication Ralph E. Hanson, 2015-01-22 Skills to Succeed in Today’s Media World Designed to give students the media literacy principles and critical thinking skills they need to become smart consumers of the media, Mass Communication: Living in the Media World provides comprehensive yet concise coverage of all aspects of mass media, along with insightful analysis and fun, conversational writing. In every chapter, students will explore the latest developments and current events that are changing the face of media today. The newly revised four-color Fifth Edition introduces a new “Media Transformations” box feature that highlights dynamic changes to how we produce and consume media. Each “Media Transformations” box includes a new infographic that helps illustrate key issues and promotes data and media literacy. Mass Communication is an interactive learning experience where you’ll explore the latest developments that are changing today’s media world. |
| beats electronics co-founder: The Spotify Play Sven Carlsson, Jonas Leijonhufvud, 2021-01-26 Two journalists chronicle the David versus many Goliaths story of the streaming music giant’s rise to success. The American edition of the revelatory Swedish book Spotify Untold, the basis of the new Netflix Original series The Playlist, out now! Steve Jobs tried to stop this moment from ever happening. Google and Microsoft made bids to preempt it. The music industry blocked it time and again. Yet, on a summer’s eve in 2011, the whiz kid CEO of a Swedish start-up celebrated his company’s US launch. In the midst of the Apple-Android tech war and a music label crusade against piracy and illegal downloading, Spotify redrew the battle lines, sent shockwaves through Silicon Valley, and got the hardline executives at Universal, Sony, and Warner to sign with its “free-mium” platform. In The Spotify Play, now adapted into an upcoming Netflix Original series, Swedish investigative tech journalists Sven Carlsson and Jonas Leijonhufvud, who covered the company from its inception, draw upon hundreds of interviews, previously untapped sources, and in-depth reporting on figures like Mark Zuckerberg, Sean Parker, Steve Jobs, Taylor Swift, Jay-Z, Pony Ma Huateng, and Jimmy Iovine. They have captured the riveting David vs. Goliath story of a disruptive innovator who played the industry giants in a quest to revolutionize the consumption of sound, building today’s largest online source of audio, with more than 50 million songs, one million-plus podcasts, and over 300 million users. Praise for The Spotify Play “Two excellent Swedish journalists recount the historic rise of the company that changed modern music not just as a riveting business tale, but as a lesson in tech geopolitics. Spotify’s Daniel Ek shows why Silicon Valley does not always win.” —David Kirkpatrick, New York Times–bestselling author of The Facebook Effect “An outsider-to-kingmaker narrative that should be read by every gun-shy entrepreneur too spooked by Silicon Valley’s giants to go head-to-head with them. . . . Carlsson and Leijonhufvud have tracked Mr. Ek’s career since the early days, and their expertise shows. The Spotify Play is . . . a revealing character study of an inventor who proved that the willingness to fight for an idea can indeed pay off—and that you don’t have to be a pirate to have fun doing it.” —Wall Street Journal |
| beats electronics co-founder: Become an Entrepreneur in The Music Business Tony Dofat, 2016-11-06 Learn the ropes to become an entrepreneur and the next mogul in the music industry. You will understand each department's job duties, earnings, and guide to pursue and master each component of this fast paced multi-billion dollar industry. Learn the characteristics and traits of an entrepreneur and how to think like one. Authored by veteran Music Producer and Entrepreneur Tony Dofat best known for his work with Sean Combs at Bad Boy Worldwide. |
| beats electronics co-founder: Selling Out Bethany Klein, 2020-07-09 The relationship between popular music and consumer brands has never been so cosy. Product placement abounds in music videos, popular music provides the soundtrack to countless commercials, social media platforms offer musicians tools for perpetual promotion, and corporate-sponsored competitions lure aspiring musicians to vie for exposure. Activities that once attracted charges of 'selling out' are now considered savvy, or even ordinary, strategies for artists to be heard and make a living. What forces have encouraged musicians to become willing partners of consumer brands? At what cost? And how do changes in popular music culture reflect broader trends of commercialization? Selling Out traces the evolution of 'selling out' debates in popular music culture and considers what might be lost when the boundary between culture and commerce is dismissed as a relic. |
| beats electronics co-founder: Music Production Michael Zager, 2021-08-12 In an age when the recording industry is undergoing its most radical change in over half a century, the guidance of a skilled music producer is quickly becoming indispensable for producing a great recording. Music Production: A Manual for Producers, Composers, Arrangers, and Students, Third Edition serves as a comprehensive road map for navigating the continuous transformations in the music industry and music production technologies. From dissecting compositions to understanding studio technologies, from coaching vocalists and instrumentalists to arranging and orchestration, from musicianship to marketing, advertising, and promotion, Michael Zager takes us on a tour of the world of music production and the recording industry, helping students and professionals keep pace with this rapidly changing profession. This third edition features: New interviews with eminent industry professionals Updated information on current trends in producing popular music and the impacts of the Music Modernization Act Additional material on video game music End-of-chapter assignments for course usage An instructor’s manual is available. Please email textbooks@rowman.com. |
| beats electronics co-founder: Focus On: 100 Most Popular American Male Guitarists Wikipedia contributors, |
| beats electronics co-founder: 3 Kings Zack O'Malley Greenburg, 2018-03-06 Tracing the careers of hip-hop's three most dynamic stars, this deeply reported history brilliantly examines the entrepreneurial genius of the first musician tycoons: Diddy, Dr. Dre, and Jay-Z. Being successful musicians was simply never enough for the three kings of hip-hop. Diddy, Dr. Dre, and Jay-Z lifted themselves from childhood adversity into tycoon territory, amassing levels of fame and wealth that not only outshone all other contemporary hip-hop artists, but with a combined net worth of well over $2 billion made them the three richest American musicians, period. Yet their fortunes have little to do with selling their own albums: between Diddy's Ciroc vodka, Dre's $3 billion sale of his Beats headphones to Apple, and Jay-Z's Tidal streaming service and other assets, these artists have transcended pop music fame to become lifestyle icons and moguls. Hip-hop is no longer just a musical genre; it's become a way of life that encompasses fashion, film, food, drink, sports, electronics and more -- one that has opened new paths to profit and to critical and commercial acclaim. Thanks in large part to the Three Kings -- who all started their own record labels and released classic albums before moving on to become multifaceted businessmen -- hip-hop has been transformed from a genre spawned in poverty into a truly global multibillion-dollar industry. These men are the modern embodiment of the American Dream, but their stories as great thinkers and entrepreneurs have yet to be told in full. Based on a decade of reporting, and interviews with more than 100 sources including hip-hop pioneers Russell Simmons and Fab 5 Freddy; new-breed executives like former Def Jam chief Kevin Liles and venture capitalist Troy Carter; and stars from Swizz Beatz to Shaquille O'Neal, 3 Kings tells the fascinating story of the rise and rise of the three most influential musicians in America. |
| beats electronics co-founder: Billboard , 2010-01-09 In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends. |
| beats electronics co-founder: Billboard , 2010-10-02 In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends. |
| beats electronics co-founder: Computerworld , 1990-07-30 For more than 40 years, Computerworld has been the leading source of technology news and information for IT influencers worldwide. Computerworld's award-winning Web site (Computerworld.com), twice-monthly publication, focused conference series and custom research form the hub of the world's largest global IT media network. |
| beats electronics co-founder: Edexcel Business A Level Year 2 Ian Marcouse, 2016-08-15 Exam Board: Edexcel Level: AS/A-level Subject: Business First Teaching: September 2015 First Exam: June 2017 Topics are broken down to short, clear chapters, that are all structured in the same way, so students can build their understanding with ease. - Covers each syllabus area in the detail you need, with exercises that have enough depth and variety to give full class and homework coverage - Brings the business world into the classroom with real examples used extensively throughout the text, in extra cases and in end-of-chapter exercises - Features to help reinforce student understanding - in every chapter there's Real Business, an Evaluation and Logic Chain, but also the brand new '5 Whys and a How' which will help students tackle exam questions |
| beats electronics co-founder: Two Beats Ahead Panos A. Panay, R. Michael Hendrix, 2021-04-08 'Groundbreaking' Amy Cuddy, bestselling author of Presence 'A roadmap for innovators, entrepreneurs and those seeking new avenues for exploring and reimagining the future' Deepak Chopra Musicians are masters of innovation, constantly finding new ways to adapt to accelerating change and staying ahead of the beat. ------------------------------------------------------------------- In Two Beats Ahead, Michael Hendrix and Panos Panay demystify the artistic process of some of the greatest creative minds of our time and reveal what they can teach us about creativity. Drawing from first person interviews, you'll learn the secrets of collaboration from Beyoncé and Pharrell Williams, grasp the value of experimentation with Radiohead and Imogen Heap, learn how to prototype with Jimmy Iovine, hear why Justin Timberlake thinks you should 'dare to suck', understand the power of reinvention from Gloria Estefan, and the art of producing from T Bone Burnett and Hank Shocklee, co-founder of Public Enemy. A musical mindset is a revolutionary framework for creating and innovating in a dynamic world. Two Beats Ahead shows you how ------------------------------------------------------------------- 'Inspiration for anyone looking to expand the reach of their creativity' Tim Brown, author of Change By Design 'Based on their course at Berklee, Michael and Panos show that a musician's perspective, much like a designers perspective, can unlock inspiration and innovation, no matter who you are' David Kelley, founder of IDEO and the Stanford d.school |
| beats electronics co-founder: Yayavar Siddharth Kumar, Shriya Seetha, Yayavar is an anthology beautifully written by young talented writers of India. |
| beats electronics co-founder: F&S Index United States Annual , 1999 |
| beats electronics co-founder: Do More Faster Brad Feld, David G. Cohen, 2010-10-01 Practical advice from some of today's top early stage investors and entrepreneurs TechStars is a mentorship-driven startup accelerator with operations in three U.S. cities. Once a year in each city, it funds about ten Internet startups with a small amount of capital and surrounds them with around fifty top Internet entrepreneurs and investors. Historically, about seventy-five percent of the companies that go through TechStars raise a meaningful amount of angel or venture capital. Do More Faster: TechStars Lessons to Accelerate Your Startup is a collection of advice that comes from individuals who have passed through, or are part of, this proven program. Each vignette is an exploration of information often heard during the TechStars program and provides practical insights into early stage entrepreneurship. Contains seven sections, each focusing on a major theme within the TechStars program, including idea and vision, fundraising, legal and structure, and work/life balance Created by two highly regarded experts in the world of early stage investing Essays in each section come from the experienced author team as well as TechStar mentors, entrepreneurs, and founders of companies While you'll ultimately have to make your own decisions about what's right for your business, Do More Faster: TechStars Lessons to Accelerate Your Startup can get your entrepreneurial endeavor headed in the right direction. |
| beats electronics co-founder: The Dynamic Manager's Guide to Marketing & Advertising Dave Donelson, 2010 Businesses that thrive-and the managers who run them-have one thing in common: they make their decisions based on meeting their customers' needs. They are good marketers. Dave Donelson distills the experiences of hundreds of such business owners-and his own as an entrepreneur and consultant-into this guide to attracting customers, persuading them to buy, and turning them into customers for life. Learn how to increase the return on your advertising investment by following a few basic rules of the game. Find out what makes your customers tick and why they buy from you-or your competition. Discover how to build your profits on a solid foundation of good marketing skills. In the first two sections, managers and entrepreneurs just like you tell how they handle the nitty-gritty details of creating ads, buying media, designing promotions, and all the many other tasks of good marketing. Insightful case studies of small companies across the country-retailers, manufacturers, service providers, and more-help you see how marketing drives successful business strategy. As a bonus, section three contains twenty-three promotions and ad campaigns you can use. Study them, run them, or adapt them to your specific needs-they've all been proven to work for businesses just like yours. The Dynamic Manager's Guide To Marketing & Advertising isn't about theory-it's about how to succeed in the real world of small business. |
| beats electronics co-founder: Billboard , 2010-10-02 In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends. |
| beats electronics co-founder: Billboard , 1996-05-04 In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends. |
| beats electronics co-founder: Billboard , 2005-03-26 In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends. |
| beats electronics co-founder: CMJ New Music Monthly , 2003-12 CMJ New Music Monthly, the first consumer magazine to include a bound-in CD sampler, is the leading publication for the emerging music enthusiast. NMM is a monthly magazine with interviews, reviews, and special features. Each magazine comes with a CD of 15-24 songs by well-established bands, unsigned bands and everything in between. It is published by CMJ Network, Inc. |
| beats electronics co-founder: The Wall Street Journal Guide to Understanding Your Taxes Scott R. Schmedel, Kenneth M. Morris, Alan M. Siegel, 1994 Easy-to-use and designed for use all year long, this uncomplicated, graphic approach to the often bewildering world of taxes is the perfect companion to annual preparation guides and an ideal planning primer. 200 four-color and black-and-white photos, diagrams, and charts. |
| beats electronics co-founder: The Gadget Show , 2014-03-20 Channel 5’s The Gadget Show finally has its own Shiny New Book. Here, the presenters of the show bring you their complete guide to gadgets, punishing and pushing every conceivable type of technology to the limit – scouring the globe for the latest and most breath-taking new tech. Read all about the firsts, the worsts and the downright most ridiculous inventions in gadget history. Discover the best ever gadgets in our top ten lists, reviews and head-to-head gadget face-offs; find out all you want to know about Jason, Rachel, Polly and Jon and even learn how to make your own mobile phone charging trousers or leaf blowing hoverboard. Get your geek on with Polly’s top Techy Thrills, Jon’s G Ratings and revealing interviews with visionary inventors and celebrity gadget testers, and uncover the secrets behind the tech they really don’t want you to know about. This is the book The Gadget Show fans have been waiting for, complete with puzzles, quizzes and a look behind the scenes – what goes on in the studio and on the road, and what happens to all the gadgets after the show? A must have techfest for gadget fans everywhere. |
| beats electronics co-founder: Billboard , 1996-02-24 In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends. |
| beats electronics co-founder: The Future of Physiology: 2020 and Beyond George E. Billman, Geoffrey A. Head, 2021-07-30 This Research Topic eBook includes articles from Volume I and II of The Future of Physiology: 2020 and Beyond series: Research Topic “The Future of Physiology: 2020 and Beyond, Volume I” Research Topic “The Future of Physiology: 2020 and Beyond, Volume II” The term Physiology was introduced in the 16th century by Jean Francois Fernel to describe the study of the normal function of the body as opposed to pathology, the study of disease. Over the ensuing centuries, the concept of physiology has evolved and a central tenet that unites all the various sub-disciplines of physiology has emerged: the quest to understand how the various components of an organism from the sub-cellular and cellular domain to tissue and organ levels work together to maintain a steady state in the face of constantly changing and often hostile environmental conditions. It is only by understanding normal bodily function that the disruptions that leads to disease can be identified and corrected to restore the healthy state. During the summer of 2009, I was invited by Dr. Henry Markram, one of the founders of the “Frontiers In” series of academic journals, to serve as the Field Chief Editor and to launch a new Open-access physiology journal that would provide a forum for the free exchange of ideas and would also meet the challenge of integrating function from molecules to the intact organism. In considering the position, I needed to answer two questions: 1) What exactly is Open-access publishing?; and 2) What could Frontiers in Physiology add to the already crowded group of physiology related journals? As a reminder, the traditional model of academic publishing “is a process by which academic scholars provide material, reviewing, and editing expertise for publication, free of charge, then pay to publish their work” and, to add insult to injury, they and their colleagues must pay the publisher a fee (either directly or via an institutional subscription) to read their published work [slightly modified from the “The Devil’s Dictionary of Publishing” Physiology News (the quarterly newsletter of the Physiological Society) Spring 2019: Issue 114, page 8]. In the traditional model, the publisher, not the authors, owns the copyright such that the author must seek permission and may even be required to pay a fee to re-use their own material (such as figures) in other scholarly articles (reviews, book chapters, etc.). In contrast, individuals are never charged a fee to read articles published in open-access journals. Thus, scholars and interested laymen can freely access research results (that their tax dollars paid for!) even if their home institution does not have the resources to pay the often exorbitant subscription fees. Frontiers takes the open-access model one step further by allowing authors (rather than the publisher) to retain ownership (i.e., the copyright) of their intellectual property. Having satisfied the first question, I then considered whether a new physiology journal was necessary. At that point in time there were no open-access physiology journals, and further, many aspects of physiology were not covered in the existing journals. Frontiers afforded the unique opportunity to provide a home for more specialized sections under the general field journal, Frontiers in Physiology, with each section having an independent editor and editorial board. I therefore agreed to assume the duties of Field Chief Editor in November 2009. Frontiers in Physiology was launched in early 2010 and the first articles were published in April 2010. Since these initial publications, we have published over 10,000 articles and have become the most cited physiology journal. Clearly we must be fulfilling a critical need. Now that it has been over a decade since Frontiers in Physiology was launched, it is time to reflect upon what has been accomplished in the last decade and what questions and issues remain to be addressed. Therefore, it is the goal of this book to evaluate the progress made during the past decade and to look forward to the next. In particular, the major issues and expected developments in many of the physiology sub-disciplines will be explored in order to inspire and to inform readers and researchers in the field of physiology for the year 2020 and beyond. A brief summary of each chapter follows: In chapter 1, Billman provides a historical overview of the evolution of the concept of homeostasis. Homeostasis has become the central unifying concept of physiology and is defined as a self-regulating process by which a living organism can maintain internal stability while adjusting to changing external conditions. He emphasizes that homeostasis is not static and unvarying but, rather, it is a dynamic process that can change internal conditions as required to survive external challenges and can be said to be the very basis of life. He further discusses how the concept of homeostasis has important implications with regards to how best to understand physiology in intact organisms: the need for more holistic approaches to integrate and to translate this deluge of information obtained in vitro into a coherent understanding of function in vivo. In chapter 2, Aldana and Robeva explore the emerging concept of the holobiont: the idea that every individual is a complex ecosystem consisting of the host organism and its microbiota. They stress the need for multidisciplinary approaches both to investigate the symbiotic interactions between microbes and multicellular organisms and to understand how disruptions in this relationship contributes to disease. This concept is amplified in chapter 3 in which Pandol addresses the future of gastrointestinal physiology ,emphasizing advances that have been made by understanding the role that the gut microbiome plays in both health and in disease. Professor Head, in chapter 4, describes areas in the field of integrative physiology that remain to be examined, as well as the potential for genetic techniques to reveal physiological processes. The significant challenges of developmental physiology are enumerated by Burggren in chapter 5. In particular, he analyzes the effects of climate change (environmentally induced epigenetic modification) on phenotype expression. In chapter 6, Ivell and Annad-Ivell highlight the major differences between the reproductive system and other organ systems. They conclude that the current focus on molecular detail is impeding our understanding of the processes responsible for the function of the reproductive organs, echoing and amplifying the concepts raised in chapter 1. In chapter 7, Costa describes the role of both circadian and non-circadian biological “clocks” in health and disease, thereby providing additional examples of integrated physiological regulation. Coronel, in chapter 8, provides a brief history of the development of cardiac electrophysiology and then describes areas that require further investigation and includes tables that list specific questions that remain to be answered. In a similar manner, Reiser and Janssen (chapter 9) summarize some of the advancements made in striated muscle physiology during the last decade and then discuss likely trends for future research; to name a few examples, the contribution of gender differences in striated muscle function, the mechanisms responsible of age-related declines in muscle mass, and role of exosome-released extracellular vesicles in pathophysiology. Meininger and Hill describe the recent advances in vascular physiology (chapter 10) and highlight approaches that should facilitate our understanding of the vascular processes that maintain health (our old friend homeostasis) and how disruptions in these regulatory mechanisms lead to disease. They also stress the need for investigators to exercise ethical vigilance when they select journals to publish in and meetings to attend. They note that the proliferation of profit driven journals of dubious quality threatens the integrity of not only physiology but science in general. The pathophysiological consequences of diabetes mellitus are discussed in chapters 11 and 12. In chapter 11, Ecelbarger addresses the problem of diabetic nephropathy and indicates several areas that require additional research. In chapter 12, Sharma evaluates the role of oxidative damage in diabetic retinopathy, and then proposes that the interleukin-6-transsignaling pathway is a promising therapeutic target for the prevention of blindness in diabetic pateints. Bernardi, in chapter 13, after briefly reviewing the considerable progress that has been achieved in understanding mitochondrial function, lists the many questions that remain to be answered. In particular, he notes several areas for future investigation including (but not limited to) a more complete understanding of inner membrane permeability changes, the physiology of various cation channels, and the role of mitochondrial DNA in disease. In chapter 14, using Douglas Adam’s “The Hitchhikers Guide to the Universe” as a model, Bogdanova and Kaestner address the question why a young person should study red blood cell physiology and provide advice for early career scientists as they establish independent laboratories. They the, describe a few areas that merit further attention, not only related to red blood cell function, but also to understanding the basis for blood related disease, and the ways to increase blood supplies that are not dependent on blood donors. Finally, the last two chapters specifically focus on non-mammalian physiology. In chapter 15, Scanes asks the question, are birds simply feathered mammals, and then reviews several of the significant differences between birds and mammals, placing particular emphasis on differences in gastrointestinal, immune, and female reproductive systems. In the final chapter (chapter 16) Anton and co-workers stress that since some 95% of living animals species are invertebrates, invertebrate physiology can provide insights into the basic principles of animal physiology as well as how bodily function adapts to environmental changes. The future of Physiology is bright; there are many important and interesting unanswered questions that will require further investigation. All that is lacking is sufficient funding and a cadre of young scientists trained to integrate function from molecules to the intact organism. George E. Billman, Ph.D, FAHA, FHRS, FTPS Department of Physiology and Cell Biology The Ohio State University Columbus OH, United States |
| beats electronics co-founder: The Little Book That Still Beats the Market Joel Greenblatt, 2010-09-07 In 2005, Joel Greenblatt published a book that is already considered one of the classics of finance literature. In The Little Book that Beats the Market—a New York Times bestseller with 300,000 copies in print—Greenblatt explained how investors can outperform the popular market averages by simply and systematically applying a formula that seeks out good businesses when they are available at bargain prices. Now, with a new Introduction and Afterword for 2010, The Little Book that Still Beats the Market updates and expands upon the research findings from the original book. Included are data and analysis covering the recent financial crisis and model performance through the end of 2009. In a straightforward and accessible style, the book explores the basic principles of successful stock market investing and then reveals the author’s time-tested formula that makes buying above average companies at below average prices automatic. Though the formula has been extensively tested and is a breakthrough in the academic and professional world, Greenblatt explains it using 6th grade math, plain language and humor. He shows how to use his method to beat both the market and professional managers by a wide margin. You’ll also learn why success eludes almost all individual and professional investors, and why the formula will continue to work even after everyone “knows” it. While the formula may be simple, understanding why the formula works is the true key to success for investors. The book will take readers on a step-by-step journey so that they can learn the principles of value investing in a way that will provide them with a long term strategy that they can understand and stick with through both good and bad periods for the stock market. As the Wall Street Journal stated about the original edition, “Mr. Greenblatt…says his goal was to provide advice that, while sophisticated, could be understood and followed by his five children, ages 6 to 15. They are in luck. His ‘Little Book’ is one of the best, clearest guides to value investing out there.” |
| beats electronics co-founder: Billboard , 1983-01-29 In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends. |
| beats electronics co-founder: Popular Mechanics , 1945-05 Popular Mechanics inspires, instructs and influences readers to help them master the modern world. Whether it’s practical DIY home-improvement tips, gadgets and digital technology, information on the newest cars or the latest breakthroughs in science -- PM is the ultimate guide to our high-tech lifestyle. |
| beats electronics co-founder: Dealerscope Consumer Electronics Marketplace , 1999 |
| beats electronics co-founder: Business Week , 1970 |
| beats electronics co-founder: Because You Are Mine Part I Beth Kery, 2012-07-31 THE NEW YORK TIMES BESTSELLING PHENOMENON From Beth Kery, the national bestselling author of Explosive, comes a red-hot romance like no other—where the rules of attraction are broken with that first electrifying touch. Meet Francesca and Ian. The fantasies of what’s to come begin… Because You Are Mine, Part I Because You Tempt Me It starts with that first look, when you know you have to have him… Francesca Arno has been commissioned to create a grand centerpiece painting for the lobby of Ian Noble’s new skyscraper. It’s at a cocktail party in her honor that she first meets him—and the attraction is immediate for Francesca. It’s also bewildering. She’s not used to such a wholesale sexual response to a stranger. Enigmatic, darkly intense, with a commanding presence, Ian completely unnerves her. And she likes it. For Ian, she’s the kind of woman he can’t resist—one that comes all too rarely: a true innocent. But he can sense in her a desire to open up, to experiment, to give herself to the fantasies of a man in control. The first kiss, the first caress, the first challenge for a woman who craves what she’s never had—a man who gets what he wants. More to come. Don't miss Because You Are Mine, Part II, available 8/7 |
| beats electronics co-founder: Computerworld , 1992-11-16 For more than 40 years, Computerworld has been the leading source of technology news and information for IT influencers worldwide. Computerworld's award-winning Web site (Computerworld.com), twice-monthly publication, focused conference series and custom research form the hub of the world's largest global IT media network. |
| beats electronics co-founder: Network World , 2000-02-07 For more than 20 years, Network World has been the premier provider of information, intelligence and insight for network and IT executives responsible for the digital nervous systems of large organizations. Readers are responsible for designing, implementing and managing the voice, data and video systems their companies use to support everything from business critical applications to employee collaboration and electronic commerce. |
| beats electronics co-founder: Billboard , 1995-06-17 In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends. |
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