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| beh c18 column chemistry: Chemical/Instrumental Approaches to the Evaluation of Wine Chemistry Rosa Perestrelo, José S. Câmara, 2020-05-27 Wine is a widely consumed beverage due to its unique and pleasant sensory properties. Wine is composed of more than one thousand chemical compounds (e.g., alcohols, esters, acids, terpenoids, phenolic compounds, flavonoids, anthocyanins, minerals, and vitamins, among others) resulting from several chemical and biochemical processes. Microextraction techniques in tandem with high-resolution analytical instruments have been applied by wine researchers to expand the knowledge of wine’s chemical composition with the purposes of improving wine quality, supporting winemaker decisions related to the winemaking process, and guaranteeing the authenticity of wine. As a result, we proposed “Chemical/Instrumental Approaches to the Evaluation of Wine Chemistry” as a topic for a Special Issue in Molecules. This Special Issue aims to provide an update on state-of-the-art extraction procedures (e.g., solid-phase microextraction (SPME)) and analytical tools (e.g., nuclear magnetic resonance (NMR), inductively coupled plasma mass spectrometry (ICP-MS), ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS)), emphasizing their use as suitable platforms for the establishment of the chemical composition of wine (volatomic profile, antioxidants, phenolic pattern, and elemental composition, among others). Information related to wine sensorial properties, contaminants, authenticity, and chemometric tools used for data treatment are described in this Issue. |
| beh c18 column chemistry: Ultra-High Performance Liquid Chromatography and Its Applications Q. Alan Xu, 2013-04-01 Explores both the benefits and limitations of new UHPLC technology High performance liquid chromatography (HPLC) has been widely used in analytical chemistry and biochemistry to separate, identify, and quantify compounds for decades. The science of liquid chromatography, however, was revolutionized a few years ago with the advent of ultra-high performance liquid chromatography (UHPLC), which made it possible for researchers to analyze sample compounds with greater speed, resolution, and sensitivity. Ultra-High Performance Liquid Chromatography and Its Applications enables readers to maximize the performance of UHPLC as well as develop UHPLC methods tailored to their particular research needs. Readers familiar with HPLC methods will learn how to transfer these methods to a UHPLC platform and vice versa. In addition, the book explores a variety of UHPLC applications designed to support research in such fields as pharmaceuticals, food safety, clinical medicine, and environmental science. The book begins with discussions of UHPLC method development and method transfer between HPLC and UHPLC platforms. It then examines practical aspects of UHPLC. Next, the book covers: Coupling UHPLC with mass spectrometry Potential of shell particles in fast liquid chromatography Determination of abused drugs in human biological matrices Analyses of isoflavones and flavonoids Therapeutic protein characterization Analysis of illicit drugs The final chapter of the book explores the use of UHPLC in drug metabolism and pharmacokinetics studies for traditional Chinese medicine. With its frank discussions of UHPLC's benefits and limitations, Ultra-High Performance Liquid Chromatography and Its Applications equips analytical scientists with the skills and knowledge needed to take full advantage of this new separation technology. |
| beh c18 column chemistry: A Handbook for DNA-Encoded Chemistry Robert A. Goodnow, Jr., 2014-04-10 This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available chemical space for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods |
| beh c18 column chemistry: Cannabis Chemistry and Biology Mahmoud A. ElSohly, 2023-05-22 This book serves as an introduction to graduate students and early career researchers on chemistry and botany of the cannabis plant. Cannabis botany, propagation, biotechnology, chemistry, cannabinoids and their biosynthesis, chemovars of cannabis and their identification as well as the other chemical classes of compounds known to exist in the plant. Analytical method are discussed to establish identity and Potency changes over the years in the United States. This book will build a base of knowledge on the complexity of cannabis chemistry. Features Introduction to the fundamental chemistry and botany of Cannabis. State of the art research on Cannabis sativa. The history, botany, major chemical classes of cannabis as well as methods of analysis and potency trends over several decades in the United States. Written by prominent scientists in the field of cannabis. The Cannabis Chemistry Subdivision of the American Chemical Society recently founded in 2022 the ElSohly Award sponsored by Heidolph North America in honour of Prof. Mahmoud A. ElSohly. This award provides researchers, students, and industry professionals with resources to present their work at the Spring National Meeting of the American Chemical Society at the ElSohly Award Symposium. More information: https://cann-acs.org/wp-content/uploads/2020/12/CANN-Postcard-Award.pdf |
| beh c18 column chemistry: UHPLC in Life Sciences Davy Guillarme, Jean-Luc Veuthey, 2015-11-09 Since its commercial introduction in 2004, UHPLC (Ultra-High Performance Liquid Chromatography) has begun to replace conventional HPLC in academia and industry and interest in this technique continues to grow. Both the increases in speed and resolution make this an attractive method; particularly to the life sciences and more than 1500 papers have been written on this strongly-evolving topic to date. This book provides a solid background on how to work with UHPLC and its application to the life sciences. The first part of the book covers the basics of this approach and the specifics of a UHPLC system, providing the reader with a solid background to working properly with such a system. The second part examines the application of UHPLC to the life sciences, with a focus on drug analysis strategies. UHPLC-MS, a key technique in pharmaceutical and toxicological analyses, is also examined in detail. The editors (Davy Guillarme and Jean-Luc Veuthey) were some of the earliest adopters of UHPLC and have published and lectured extensively on this topic. Between them they have brought together an excellent team of contributors from Europe and the United States, presenting a wealth of expertise and knowledge. This book is an essential handbook for anyone wishing to adopt an UHPLC system in either an academic or industrial setting and will benefit postgraduate students and experienced workers alike. |
| beh c18 column chemistry: Novel Developments in Pharmaceutical and Biomedical Analysis Atta-ur- Rahman, Sibel A. Ozkan, Rida Ahmed, 2018-04-24 Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents information about a selection of analytical techniques. Readers will find information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. Novel Developments in Pharmaceutical and Biomedical Analysis is the second volume of the series and covers the following topics: o Chromatographic assays of solid dosage forms and their drug dissolution studies o UHPLC method for the estimation of bioactive compounds o HILIC based LC/MS for metabolite analysis o In vitro methods for the evaluation of oxidative stress o Application of vibrational spectroscopy in studies of structural polymorphism of drugs o Electrochemical sensors based on conductive polymers and carbon nanotubes o Optical sensor arrays for pharmaceutical and biomedical analyses o Chemical applications of ionic liquids o New trends in enantioanalysis of pharmaceutical compounds |
| beh c18 column chemistry: HPLC Method Development for Pharmaceuticals Satinder Ahuja, Henrik Rasmussen, 2011-09-21 High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. - Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory - Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) - Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase |
| beh c18 column chemistry: Radiopharmaceutical Chemistry between Imaging and Endoradiotherapy Klaus Kopka, 2018-10-04 This book is a printed edition of the Special Issue Radiopharmaceutical Chemistry between Imaging and Radioendotherapy that was published in Pharmaceuticals |
| beh c18 column chemistry: Advances in Clinical Chemistry Gregory S. Makowski, 2022-03-23 Advances in Clinical Chemistry, Volume 107, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release focusing on Advances in Quantum Dots as Diagnostic Tools, Host polymorphisms and COVID-19 infection, Biomarkers in Muscle Invasive Bladder Cancer, and more. - Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science - Authored by world renowned clinical laboratory scientists, physicians and research scientists - Presents the international benchmark for novel analytical approaches in the clinical laboratory |
| beh c18 column chemistry: HPLC Columns Uwe D. Neue, 1997-07-28 An in-depth guide to HPLC column technology High-performance liquid chromatography and its derivative techniques have become the dominant analytical separation tools in the pharmaceutical, chemical, and food industries; environmental laboratories; and therapeutic drug monitoring. Although the column is the heart of the HPLC instrument and essential to its success, until now, no book has focused on the theory and practice of column technology. HPLC Columns provides thorough, state-of-the-art coverage of HPLC column technology for the practicing technician and academician alike. Along with a comprehensive discussion of the chemical and physical processes of the HPLC column, it includes fundamental principles, separation mechanisms and available technologies, column selection criteria, and special techniques. Special features include: * Comprehensive overview of state-of-the-art HPLC column technology * Explanation of the underlying principles of HPLC columns * Methods for selecting columns * Practical advice on using and applying columns, including examples * Section by M. Zoubair El Fallah on methods development * Special techniques, including preparative chromatography, continuous chromatography, and the simulated moving bed * Troubleshooting section HPLC Columns helps laboratory practitioners make better choices in column selection, methods development, and troubleshooting: it is also an excellent textbook for graduate-level courses and HPLC short courses. |
| beh c18 column chemistry: Issues in Chemical, Biological, and Medical Engineering: 2011 Edition , 2012-01-09 Issues in Chemical, Biological, and Medical Engineering: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chemical, Biological, and Medical Engineering. The editors have built Issues in Chemical, Biological, and Medical Engineering: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chemical, Biological, and Medical Engineering in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Chemical, Biological, and Medical Engineering: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| beh c18 column chemistry: Green Analytical Chemistry Mihkel Koel, Mihkel Kaljurand, 2015-11-09 Concerns about environmental pollution, global climate change and hazards to human health have increased dramatically. This has led to a call for change in chemical processes including those that are part of chemical analysis. The development of analytical chemistry continues and every new discovery in chemistry, physics, molecular biology, and materials science brings new opportunities and challenges. Yet, contemporary analytical chemistry does not consume resources optimally. Indeed, the usage of toxic chemical compounds is at the highest rate ever. All this makes the emerging field of green chemistry a “hot topic” in industrial, governmental laboratories as well as in academia. This book starts by introducing the twelve principles of green chemistry. It then goes on to discuss how the principles of green chemistry can be used to assess the ‘greenness’ of analytical methodologies. The ‘green profile’ proposed by the ACS Green Chemistry Institute is also presented. A chapter on “Greening” sample preparation describes approaches to minimizing toxic solvent use, using non-toxic alternatives, and saving energy. The chapter on instrumental methods describes existing analytical approaches that are inherently green and making non-green methods greener. The final chapter on signal acquisition describes how quantitative structure-property relationship (QSPR) ideas could reduce experimental work thus making analysis greener. The book concludes with a discussion of how green chemistry is both possible and necessary. Green Analytical Chemistry is aimed at managers of analytical laboratories but will also interest teachers of analytical chemistry and green public policy makers. |
| beh c18 column chemistry: Advances in Chromatography Nelu Grinberg, Peter W. Carr, 2024-08-20 For six decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. The clear presentation of topics and vivid illustrations for which this series has become known make the material accessible and engaging to analytical, biochemical, organic, polymer, and pharmaceutical chemists at all levels of technical skill. Presents an in-depth review of chaotropic chromatography. Reviews recent advances in HPLC and SFC columns packed with hybrid organic/inorganic particles. Explores new advances in nano-liquid chromatography for proteomics analysis. Outlines the heterogeneity of gangliosides and advances in the chromatographic techniques used in their separation. |
| beh c18 column chemistry: Recent Advances in Applied Science and Engineering Dr. Ankita Saini, Dr.Sunil Kumar Saini, 2024-02-14 Recent Advances in Applied Science and Engineering represents a thorough and state-of-the-art exploration of the most recent developments across various disciplines within the fields of applied science and engineering. Each chapter provides in-depth analyses of emerging technologies, methodologies, and discoveries, emphasizing the practical applications of these advancements to address real-world challenges. Furthermore, the book not only showcases recent achievements but also engages in discussions about potential future directions and challenges in applied science and engineering. This forward-looking approach offers readers a roadmap for upcoming research areas and opportunities for innovation. Serving as an indispensable resource, this book provides a comprehensive overview of the latest developments in these rapidly evolving fields. Whether a researcher or student, readers will find this book to be a valuable reference for staying informed about the most recent advancements shaping the future of applied science and engineering. |
| beh c18 column chemistry: Editors’ Showcase: Chemical Biology John D. Wade, 2022-09-23 |
| beh c18 column chemistry: Handbook of Methods and Instrumentation in Separation Science , 2009-11-11 Handbook of Methods and Instrumentation in Separation Science, Volume 1 provides concise overviews and summaries of the main methods used for separation. It is based on the Encyclopedia of Separation Science. The handbook focuses on the principles of methods and instrumentation. It provides general concepts concerning the subject matter; it does not present specific procedures. This volume discusses the separation processes including affinity methods, analytical ultracentrifugation, centrifugation, chromatography, and use of decanter centrifuge and dye. Each methodology is defined and compared with other separation processes. It also provides specific techniques, principles, and theories concerning each process. Furthermore, the handbook presents the applications, benefits, and validation of the processes described in this book. This handbook is an excellent reference for biomedical researchers, environmental and production chemists, flavor and fragrance technologists, food and beverage technologists, academic and industrial librarians, and nuclear researchers. Students and novices will also find this handbook useful for practice and learning. - One-stop source for information on separation methods - General overviews for quick orientation - Ease of use for finding results fast - Expert coverage of major separation methods - Coverage of techniques for all sizes of samples, pico-level to kilo-level |
| beh c18 column chemistry: Modern Size-Exclusion Liquid Chromatography Andre Striegel, Wallace W. Yau, Joseph J. Kirkland, Donald D. Bly, 2009-07-31 The Second Edition of Modern Size-Exclusion Chromatography offers a complete guide to the theories, methods, and applications of size-exclusion chromatography. It provides an unparalleled, integrated, up-to-date treatment of gel permeation and gel filtration chromatography. With its detailed descriptions of techniques, data handling, compilations of information on columns and column packings, and tables of important solvents and reference materials, the book offers readers everything they need to take full advantage of this popular macromolecular characterization technique. Since publication of the first edition in 1979, there have been many important advances in the field of size-exclusion chromatography. This Second Edition brings the book thoroughly up to date, with expert coverage of: New and emerging industrial and research applications Practical aspects of size-exclusion chromatography (SEC) and multidetector and multidimensional SEC technologies for polymer architecture and copolymer analysis Updated information on the latest equipment and techniques New best practices for the lab SEC in relation to polymer characterization techniques such as GPEC, LCCC, and rheology Throughout the text, detailed examples guide you step by step through all the latest techniques and applications. With its extensive revisions and updates written by leading experts and pioneers in the field, Modern Size-Exclusion Liquid Chromatography remains the definitive resource for the broad range of researchers and scientists who use HPLC and GPC methods. |
| beh c18 column chemistry: Chemistry for a Clean and Healthy Planet Ponnadurai Ramasami, Minu Gupta Bhowon, Sabina Jhaumeer Laulloo, Henri Li Kam Wah, 2019-09-03 These proceedings gather carefully selected, peer-reviewed contributions from the International Conference on Pure and Applied Chemistry (ICPAC 2018). The event, the latest installment in a biennial conference series, was held in July 2018 in Mauritius. The respective chapters in this unique collection reflect a wide range of fundamental and applied research in the chemical sciences and various interdisciplinary subjects. In addition to reviews, they highlight cutting-edge advances. |
| beh c18 column chemistry: The HPLC-MS Handbook for Practitioners Stavros Kromidas, 2017-06-22 Dieses prägnante, kompakte und übersichtliche Fachbuch befasst sich ausschließlich mit den praktischen Aspekten der HPLC-MS-Kopplung und vermittelt detailliert die Kenntnisse, um diese Methode effizient einsetzen zu können. Nach einem Überblick über den aktuellen Wissensstand rund um HPLC-MS und die eingesetzten Instrumente werden alle relevanten Aspekte der Methodenentwicklung erläutert. Ein Kapitel zeigt Tipps und Tricks und enthält Anwenderberichte zu den Vorteilen und Tücken bei der Anwendung der Methode in der Praxis. Abgerundet werden die Darstellungen durch einen Ausblick auf zukünftige Entwicklungen renommierter Hersteller. |
| beh c18 column chemistry: Recent Trends in Pharmaceutical Analytical Chemistry Constantinos K. Zacharis, 2021-09-01 This book covers the most recent research trends and applications of Pharmaceutical Analytical Chemistry. The included topics range from the adulteration of dietary supplements, to the determination of drugs in biological samples with the aim to investigate their pharmacokinetic properties. |
| beh c18 column chemistry: Issues in Analysis, Measurement, Monitoring, Imaging, and Remote Sensing Technology: 2012 Edition , 2013-01-10 Issues in Analysis, Measurement, Monitoring, Imaging, and Remote Sensing Technology: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chromatography. The editors have built Issues in Analysis, Measurement, Monitoring, Imaging, and Remote Sensing Technology: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chromatography in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Analysis, Measurement, Monitoring, Imaging, and Remote Sensing Technology: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| beh c18 column chemistry: Optimization in HPLC Stavros Kromidas, 2021-08-06 Learn to maximize the performance of your HPLC or UHPLC system with this resource from leading experts in the field Optimization in HPLC: Concepts and Strategies delivers tried-and-tested strategies for optimizing the performance of HPLC and UHPLC systems for a wide variety of analytical tasks. The book explains how to optimize the different HPLC operation modes for a range of analyses, including small molecules, chiral substances, and biomolecules. It also shows readers when and how computational tools may be used to optimize performance. The practice-oriented text describes common challenges faced by users and developers of HPLC and UHPLC systems, as well as how those challenges can be overcome. Written for first-time and experienced users of HPLC technology and keeping pace with recent developments in HPLC instrumentation and operation modes, this comprehensive guide leaves few questions unanswered. Readers will also benefit from the inclusion of: A thorough introduction to optimization strategies for different modes and uses of HPLC, including working under regulatory constraints An exploration of computer aided HPLC optimization, including ChromSwordAuto and Fusion QbD A treatment of current challenges for HPLC users in industry as well as large and small analytical service providers Discussions of current challenges for HPLC equipment suppliers Tailor-made for analytical chemists, chromatographers, pharmacologists, toxicologists, and lab technicians, Optimization in HPLC: Concepts and Strategies will also earn a place on the shelves of analytical laboratories in academia and industry who seek a one-stop reference for optimizing the performance of HPLC systems. |
| beh c18 column chemistry: Nutriomics Devarajan Thangadurai, Saher Islam, Leo M.L. Nollet, Juliana Adetunji, 2022-05-16 Implementation of robust omics technologies enables integrative and holistic interrogation related to nutrition by labeling biomarkers to empirically assess the dietary intake. Nutriomics: Well-being through Nutrition aims to enhance scientific evidence based on omics technologies and effectiveness of nutrition guidelines to promote well-being. It provides deep understanding towards nutrients and genotype effects on disease and health status. It also unveils the nutrient–health relation at the population and individual scale. This book helps to design the precise nutritional recommendations for prevention or treatment of nutrition-related syndromes. Nutriomics: Well-being through Nutrition focuses on: The impact of molecular approaches to revolutionize nutrition research for human well-being Various biomarkers for bioactive ingredient analysis in nutritional intervention research Potential of transcriptomic, genomic, proteomic, metabolomic, and epigenomic tools for nutrition care practices Recent updates on applications of omics technologies towards personalized nutrition Providing comprehensive reviews about omics technologies in nutritional science, Nutriomics: Well-being through Nutrition serves as an advanced source of reference for food developers, nutritionists, and dietary researchers to investigate and evaluate nutriomics tools for development of customized nutrition and food safety. It is also a useful source for clinicians and food industry officials who require intense knowledge about emerging dietary-related tools to revolutionize the nutrition industry. This is a volume in the Food Analysis and Properties series, a series designed to provide state-of-art coverage on topics to the understanding of physical, chemical, and functional properties of foods. |
| beh c18 column chemistry: Supramolecular Nucleic Acid Chemistry James Tucker, Janarthanan Jayawickramarajah, 2020-10-28 This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact. |
| beh c18 column chemistry: Carbamates—Advances in Research and Application: 2012 Edition , 2012-12-26 Carbamates—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Carbamates. The editors have built Carbamates—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Carbamates in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Carbamates—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| beh c18 column chemistry: Comprehensive Guide to HILIC Waters Corporation, 2014-04-21 The Comprehensive Guide to HILIC: Hydrophilic Interaction Chromatography, a 72-page book, illustrates how HILIC works and how separation scientists can improve their success in separating and quantifying polar compounds in a variety of sample matrices. Looking for something else? Learn a new technique or technology with the Waters Primers Series, view other titles available here: http://www.wiley.com/go/waters |
| beh c18 column chemistry: Nitriles—Advances in Research and Application: 2013 Edition , 2013-06-21 Nitriles—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Acrylonitrile. The editors have built Nitriles—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Acrylonitrile in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nitriles—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| beh c18 column chemistry: Chinmedomics Xijun Wang, Aihua Zhang, Hui Sun, 2015-07-15 Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future. - Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method - Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications - Edited by the leading experts of research related to Chinmedomics |
| beh c18 column chemistry: Advanced Dairy Chemistry, Volume 2 Paul L. H. McSweeney, Patrick F. Fox, James A. O'Mahony, 2020-12-08 The Advanced Dairy Chemistry series was first published in four volumes in the 1980s (under the title Developments in Dairy Chemistry) and revised in three volumes in the 1990s and 2000s. The series is the leading reference on dairy chemistry, providing in-depth coverage of milk proteins, lipids, lactose, water and minor constituents. Advanced Dairy Chemistry Volume 2: Lipids, Fourth Edition, is unique in the literature on milk lipids, a broad field that encompasses a diverse range of topics, including synthesis of fatty acids and acylglycerols, compounds associated with the milk fat fraction, analytical aspects, behavior of lipids during processing and their effect on product characteristics, product defects arising from lipolysis and oxidation of lipids, as well as nutritional significance of milk lipids. In the years since the publication of the third edition there have been significant developments in milk lipids and these are reflected in changes to this volume. Most topics included in the third edition are retained in the current edition, which has been updated; in some cases, new authors have given their perspective on certain topics. Chapters on nutritional significance of dairy lipids have been considerably revised. This authoritative work summarizes current knowledge on milk lipids and suggests areas for further work. It will be very valuable to dairy scientists, chemists and others working in dairy research or in the dairy industry. |
| beh c18 column chemistry: Peptide Therapeutics Ved Srivastava, 2019-08-28 Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization. CMC can often become a rate-limiting step due to lack of knowledge and lack of a formal policy or guidelines on CMC for peptide-based drugs. Regulators use a risk-based approach, reviewing applications on a case-by-case basis. Peptide Therapeutics: Strategy and Tactics for Chemistry, Manufacturing, and Controls covers efficient manufacturing of peptide drug substances, a review of the process for submitting applications to the regulatory authority for drug approval, a holistic approach for quality attributes and quality control from a regulatory perspective, emerging analytical tools for the characterisation of impurities, and the assessment of stability. This book is an essential reference work for students and researchers, in both academia and industry, with an interest in learning about CMC, and facilitating development and manufacture of peptide-based drugs. |
| beh c18 column chemistry: Selection of the HPLC Method in Chemical Analysis Serban C. Moldoveanu, Victor David, 2016-11-01 Selection of the HPLC Method in Chemical Analysis serves as a practical guide to users of high-performance liquid chromatography and provides criteria for method selection, development, and validation. High-performance liquid chromatography (HPLC) is the most common analytical technique currently practiced in chemistry. However, the process of finding the appropriate information for a particular analytical project requires significant effort and pre-existent knowledge in the field. Further, sorting through the wealth of published data and literature takes both time and effort away from the critical aspects of HPLC method selection. For the first time, a systematic approach for sorting through the available information and reviewing critically the up-to-date progress in HPLC for selecting a specific analysis is available in a single book. Selection of the HPLC Method in Chemical Analysis is an inclusive go-to reference for HPLC method selection, development, and validation. - Addresses the various aspects of practice and instrumentation needed to obtain reliable HPLC analysis results - Leads researchers to the best choice of an HPLC method from the overabundance of information existent in the field - Provides criteria for HPLC method selection, development, and validation - Authored by world-renowned HPLC experts who have more than 60 years of combined experience in the field |
| beh c18 column chemistry: Frontiers in Chemistry: Rising Stars 2022 Yunping Qiu, Rosalia Maria Cigala, Daniele Contini, Juqin Zeng, Zhongzheng Yu, Alberto Rota, Sen Wang, M. Nageeb Rashed, Marianna Pannico, Carlos D.S. Brites, Fidele Tugizimana, Uttam Pal, Guigen Li, Essa M. Saied, Tsuyoshi Minami, Xiao-Peng He, Ou Chen, Basem Moosa, Clemens Zwergel, 2024-02-01 We are delighted to present the 2022 Edition of our Frontiers in Chemistry “Rising Stars” article collection. This collection showcases the high-quality work of internationally recognized researchers in the early stages of their independent careers. All Rising Star researchers were individually nominated by our Guest Editors and Chief Editors in recognition of their potential to influence the future directions in their respective fields. This year, we have selected Guest Editors who were featured as our Rising Stars in our previous collection together with Editorial Board members. The work presented here highlights the diversity of research performed across the entire breadth of chemical science and presents advances in theory, experiment and methodology with applications to compelling problems. |
| beh c18 column chemistry: Carotenoids in Nature Claudia Stange, 2016-08-02 This comprehensive, edited book explores carotenoids and their important functional roles in yeast, bacteria and plants and a profound exposition on the structures of carotenoid molecules, focusing in the first of three parts on the biosynthesis of carotenoids. The regulation of carotenoid biosynthesis in photosynthesis as well as in plant, fruits, storage roots and algae is central to the second part, and discoveries about the function of carotenoids in human health feature in the third and final part. Many helpful illustrations, explanations, overviews and examples help to bring readers up to date on relevant themes including carotenogenic genes, carotenoids in fruits and metabolic engineering. The book explores where carotenoids are synthesized in nature, including in carrots and algae. Contributing expert authors examine enzyme functions and plant models, and analyze the structure of carotenoid molecules. The function of carotenoids in photosynthesis and in photosynthetic organs as well as during fruit ripening are then explored. A whole chapter is dedicated to the latest research on apocarotenoids and further chapters cover interesting and novel themes on plastid development and the epigenetic regulation that affects carotenoid synthesis in plants. The metabolic engineering of carotenoids that has been done in fruits, plants, and seeds is another area that readers can explore, along with evidences on the function of carotenoids in human nutrition, as antioxidants, as in the control of lipid metabolism and in the absorption of carotenoids. This is a highly informative and wide-ranging work which will update researchers in the field, as well as supporting students of plant physiology and biotechnology, as supplementary reading. |
| beh c18 column chemistry: Advanced Mass Spectrometry-based Analytical Separation Techniques for Probing the Polar Metabolome Rawi Ramautar, 2021-07-13 The efficient analysis of polar and charged metabolites in biological samples remains a huge challenge in the field of metabolomics. Over the past years, novel mass spectrometry-based analytical tools have been developed to enable the sensitive and efficient profiling of polar ionogenic metabolites in various biological samples. This book gives the reader a comprehensive overview of these recent technological developments. Topics covered include the use of chemical labelling strategies for allowing the analysis of polar metabolites using reversed-phase liquid chromatography–mass spectrometry (RPLC-MS) and the latest methodological developments in RPLC-MS, hydrophilic interaction liquid chromatography (HILIC)-MS and ion-pair LC-MS approaches. Attention is also paid to developments in nano-LC-MS and capillary electrophoresis–mass spectrometry methods specifically for profiling polar metabolites in small volume biological samples. The utility of ion-mobility MS and NMR spectroscopy will also be outlined. Sample preparation is the key part in the analytical workflow employed for metabolomics. Therefore, ample emphasis will be given on recent solid-phase extraction and solid-phase micro-extraction methods. Finally, analytical techniques for chiral metabolic profiling will also be considered. Discussing the state-of-the-art of the proposed topics in one single book for probing the polar metabolome, using relevant examples, is unique and needed in the metabolomics field. This book has relevance and appeal to an international audience of analytical and biomedical researchers in industry and academia. |
| beh c18 column chemistry: Imidazole Dipeptides Victor R Preedy, 2015-08-03 Carnosine and anserine are two common histidine-derived dipeptides, also known as imidazole dipeptides, found in muscle and brain tissues of animals. Their dietary and nutritional significance lies in their antioxidant properties and a number of investigators are looking at other health benefits of the compounds. This volume surveys the current state of play in these and other areas of interest, including chemistry and biochemistry, immunology and cellular homeostasis. Chapters look in depth at some of the functions and effects in the body particularly with regard to exercise and fatigue, wound healing, cancer treatment and age-related diseases. Providing an up to date, interdisciplinary approach, this book is of great interest to researchers and professionals in chemistry, food science, nutrition, biochemistry, health sciences and sports sciences. |
| beh c18 column chemistry: Antipsoriatics—Advances in Research and Application: 2013 Edition , 2013-06-21 Antipsoriatics—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Antipsoriatics—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antipsoriatics—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| beh c18 column chemistry: Issues in Chemical, Biological, and Medical Engineering: 2013 Edition , 2013-05-01 Issues in Chemical, Biological, and Medical Engineering: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Biosystems Engineering. The editors have built Issues in Chemical, Biological, and Medical Engineering: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biosystems Engineering in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Chemical, Biological, and Medical Engineering: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| beh c18 column chemistry: Ultra Performance Liquid Chromatography Mass Spectrometry Mu Naushad, Mohammad Rizwan Khan, 2014-03-18 This book presents a unique collection of up-to-date UPLC-MS/MS (ultra performance liquid chromatography-tandem mass spectrometric) methods for the separation and quantitative determination of pesticides, capsaicinoids, heterocyclic amines, aflatoxin, perfluorochemicals, acrylamide, procyanidins and alkaloids, lactose content, phenolic compounds, vitamins, and aroma and flavor compounds in a wide variety of foods and food products. With contributions by experts in interdisciplinary fields, this reference offers practical information for readers in research and development, production, and routing analysis of foods and food products. |
| beh c18 column chemistry: Small Molecules Bridging Terrestrial Microbial Interactions in Multitrophic Systems Elisa Korenblum, Paolina Garbeva, Monica T. Pupo, 2022-06-01 |
| beh c18 column chemistry: Proceedings of 4th World Congress on Chromatography 2017 ConferenceSeries, August 07-09, 2017 Rome, Italy Key Topics : Adsorption Chromatography, Partition Chromatography, Ion Exchange Chromatography, Molecular Exclusion Chromatography, Separation Techniques in Chemistry, Spectroscopy, Affinity Chromatography, Gas Chromatography, High Performance Liquid Chromatography, Special Techniques in Chromatography, Advancement in Chromatography, Applications of Chromatography, Novel Techniques in Chromatography, Market Growth of Chromatography, |
ACQUITY UPLC and ACQUITY Premier Oligonucleotide BEH …
18 Column designed specifically for use on ACQUITY UPLCTM and ACQUITY Premier Systems. The separation of detritylated oligonucleotides on Waters second generation of hybrid-silica …
ACQUITY UPLC Columns - LCMS
ACQUITY UPLC™ BEH C 18 and C 8 columns incorporate trifunctional ligand bonding chemistries which produce superior low pH stability and ultra-low column bleed. This low pH …
HyperCHROM BEH Column - analytical group
• Excellent resistance to acids and bases (pH 1.0 -12.5) and good column life even under extreme condi ons. • Double capping technology for maximum elimina on of silicone hydroxyl residues.
Characterization and evaluation of a novel C18 column based …
In this poster, we will evaluate the pH stability and chromatographic performance of Triart C18 comparing commercially available columns, and show some application data utilizing …
Expanding the Range of PFAS in a Single Injection to Include …
Use of the Atlantis Premier BEH C18 AX Column now broadens the scope of PFAS that can be routinely detected and quantified in a single injection to include the ultra-short chain PFAS …
Technical Note - YMC
The YMC-Triart Bio C18 column demonstrates a better resolution, higher recovery and reproducibility of poly(dT) oligonucleotides compared to XBridge Oligonucleotide BEH C18 and …
ACQUITY UPLC BEH Column - PDF4PRO
Each batch of ACQUITY UPLCTM BEH material is tested chromatographically with acidic, basic and neutral analytes and the results are held to narrow specification ranges to assure …
Atlantis Premier BEH C18 AX Columns - help.waters.com
BEH C 18 AX Column. The Atlantis Premier BEH C 18 AX Column packing material is manufactured in a cGMP, ISO 9001 certified plant using ultra-pure reagents. Each batch is …
Maximize Your Resources and Simplify Scale-up with …
This work evaluated the performance of the Agilent AdvanceBio Oligonucleotide 4 μm column chemistry versus the Waters XBridge BEH C18 OBD 5μm Prep Column.
Developments in Waters Column Chemistries : BEH Technology
Similar bonded phases (C 18, C 8, Embedded Polar, Phenyl) as silica column, with comparable selectivities. Similar particle sizes as Silica (2.5, 3.5, 5, 10 μm). Improved chemical stability …
DMB-Labeled Sialic Acid Analyses Using - Waters Corporation
This application note details the application of the same scaling principles to the LC-based analysis of DMB-labeled sialic acids on the same Waters BEH C18, 130Å column chemistry.
ACQUITY UPLC BEH Columns - prep-hplc.com
Thank you for choosing a Waters® ACQUITY UPLC® BEH Column. The ACQUITY UPLC BEH packing materials were designed specifically for use with the ACQUITY UPLC System and are …
eXtended performance - imchem.fr
2.7 μm Ascentis Express C18) to three eXtended Performance Columns (2.5 μm BEH C 18, HSS T3 and CSH C18). Both core-shell and fully-porous columns yield similar results. The …
ACQUITY UPLC and ACQUITY Premier BEH Columns
Thank you for choosing a WatersTM ACQUITYTM UPLCTM and/ or ACQUITY Premier BEH Column. The ACQUITY BEH packing materials were designed specifically for use with the …
Selectivity Differences Between Three C18 Columns and the …
To illustrate the differences between different C18 columns, the separations obtained from three unique chemistries were compared at both the analytical and preparative scales. XBridge BEH …
Improved Chromatographic Analysis of Oligonucleotides with …
This application note illustrates sources of oligonucleotide loss due to adsorption on metallic column hardware (frits). Solutions, columns, and best practices for improved oligonucleotide …
XBridge Peptide BEH C18, 130Å and 300Å Columns and …
Each batch of XBridge Peptide BEH C18 Column material has been qualified with a peptide separation, and the results are held to narrow specification ranges to assure excellent, …
ACQUITY UPLC and ACQUITY PREMIER Peptide BEH C18, …
ACQUITY PREMIER Peptide BEH C 18, 130 Å or 300 Å Column. BEH C 18 specifically for use with the ACQUITY UPLC and ACQUITY 18 material excellent, reproducible performance. …
6724_IG_Atlantis Premier BEH C18 AX Columns_7x14_rev2021
The BEH 95 Å particle and the novel mixed-mode chemistry provide increased retention over a wider pH range, orthogonal selectivity to C18 columns, and a reduction in MS bleed. The …
ACQUITY UPLC and ACQUITY Premier Peptide BEH C18, 130Å …
Each batch of ACQUITY UPLC and ACQUITY Premier BEH C. 18 material is tested chromatographically with acidic, basic, and neutral analytes and has been qualified for peptide …
ACQUITY UPLC and ACQUITY Premier Oligonucleotide …
18 Column designed specifically for use on ACQUITY UPLCTM and ACQUITY Premier Systems. The separation of detritylated oligonucleotides on Waters second generation of hybrid-silica …
ACQUITY UPLC Columns - LCMS
ACQUITY UPLC™ BEH C 18 and C 8 columns incorporate trifunctional ligand bonding chemistries which produce superior low pH stability and ultra-low column bleed. This low pH …
HyperCHROM BEH Column - analytical group
• Excellent resistance to acids and bases (pH 1.0 -12.5) and good column life even under extreme condi ons. • Double capping technology for maximum elimina on of silicone hydroxyl residues.
Characterization and evaluation of a novel C18 column …
In this poster, we will evaluate the pH stability and chromatographic performance of Triart C18 comparing commercially available columns, and show some application data utilizing …
Expanding the Range of PFAS in a Single Injection to …
Use of the Atlantis Premier BEH C18 AX Column now broadens the scope of PFAS that can be routinely detected and quantified in a single injection to include the ultra-short chain PFAS …
Technical Note - YMC
The YMC-Triart Bio C18 column demonstrates a better resolution, higher recovery and reproducibility of poly(dT) oligonucleotides compared to XBridge Oligonucleotide BEH C18 and …
ACQUITY UPLC BEH Column - PDF4PRO
Each batch of ACQUITY UPLCTM BEH material is tested chromatographically with acidic, basic and neutral analytes and the results are held to narrow specification ranges to assure …
Atlantis Premier BEH C18 AX Columns - help.waters.com
BEH C 18 AX Column. The Atlantis Premier BEH C 18 AX Column packing material is manufactured in a cGMP, ISO 9001 certified plant using ultra-pure reagents. Each batch is …
Maximize Your Resources and Simplify Scale-up with …
This work evaluated the performance of the Agilent AdvanceBio Oligonucleotide 4 μm column chemistry versus the Waters XBridge BEH C18 OBD 5μm Prep Column.
Developments in Waters Column Chemistries : BEH …
Similar bonded phases (C 18, C 8, Embedded Polar, Phenyl) as silica column, with comparable selectivities. Similar particle sizes as Silica (2.5, 3.5, 5, 10 μm). Improved chemical stability …
DMB-Labeled Sialic Acid Analyses Using - Waters Corporation
This application note details the application of the same scaling principles to the LC-based analysis of DMB-labeled sialic acids on the same Waters BEH C18, 130Å column chemistry.
ACQUITY UPLC BEH Columns - prep-hplc.com
Thank you for choosing a Waters® ACQUITY UPLC® BEH Column. The ACQUITY UPLC BEH packing materials were designed specifically for use with the ACQUITY UPLC System and are …
eXtended performance - imchem.fr
2.7 μm Ascentis Express C18) to three eXtended Performance Columns (2.5 μm BEH C 18, HSS T3 and CSH C18). Both core-shell and fully-porous columns yield similar results. The …
ACQUITY UPLC and ACQUITY Premier BEH Columns
Thank you for choosing a WatersTM ACQUITYTM UPLCTM and/ or ACQUITY Premier BEH Column. The ACQUITY BEH packing materials were designed specifically for use with the …
Selectivity Differences Between Three C18 Columns and the …
To illustrate the differences between different C18 columns, the separations obtained from three unique chemistries were compared at both the analytical and preparative scales. XBridge BEH …
Improved Chromatographic Analysis of Oligonucleotides with …
This application note illustrates sources of oligonucleotide loss due to adsorption on metallic column hardware (frits). Solutions, columns, and best practices for improved oligonucleotide …
XBridge Peptide BEH C18, 130Å and 300Å Columns and …
Each batch of XBridge Peptide BEH C18 Column material has been qualified with a peptide separation, and the results are held to narrow specification ranges to assure excellent, …
ACQUITY UPLC and ACQUITY PREMIER Peptide BEH …
ACQUITY PREMIER Peptide BEH C 18, 130 Å or 300 Å Column. BEH C 18 specifically for use with the ACQUITY UPLC and ACQUITY 18 material excellent, reproducible performance. …
6724_IG_Atlantis Premier BEH C18 AX Columns_7x14_rev2021
The BEH 95 Å particle and the novel mixed-mode chemistry provide increased retention over a wider pH range, orthogonal selectivity to C18 columns, and a reduction in MS bleed. The …
ACQUITY UPLC and ACQUITY Premier Peptide BEH C18, …
Each batch of ACQUITY UPLC and ACQUITY Premier BEH C. 18 material is tested chromatographically with acidic, basic, and neutral analytes and has been qualified for peptide …
