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| developing clinical practice guidelines: Clinical Practice Guidelines We Can Trust Institute of Medicine, Board on Health Care Services, Committee on Standards for Developing Trustworthy Clinical Practice Guidelines, 2011-06-16 Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers. |
| developing clinical practice guidelines: Guidelines for Clinical Practice Institute of Medicine, Committee on Clinical Practice Guidelines, 1992-02-01 Guidelines for the clinical practice of medicine have been proposed as the solution to the whole range of current health care problems. This new book presents the first balanced and highly practical view of guidelinesâ€their strengths, their limitations, and how they can be used most effectively to benefit health care. The volume offers: Recommendations and a proposed framework for strengthening development and use of guidelines. Numerous examples of guidelines. A ready-to-use instrument for assessing the soundness of guidelines. Six case studies exploring issues involved when practitioners use guidelines on a daily basis. With a real-world outlook, the volume reviews efforts by agencies and organizations to disseminate guidelines and examines how well guidelines are functioningâ€exploring issues such as patient information, liability, costs, computerization, and the adaptation of national guidelines to local needs. |
| developing clinical practice guidelines: Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies OECD, World Health Organization, 2019-10-17 This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies. |
| developing clinical practice guidelines: Framing Opioid Prescribing Guidelines for Acute Pain National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Health Care Services, Committee on Evidence-Based Clinical Practice Guidelines for Prescribing Opioids for Acute Pain, 2020-03-20 The opioid overdose epidemic combined with the need to reduce the burden of acute pain poses a public health challenge. To address how evidence-based clinical practice guidelines for prescribing opioids for acute pain might help meet this challenge, Framing Opioid Prescribing Guidelines for Acute Pain: Developing the Evidence develops a framework to evaluate existing clinical practice guidelines for prescribing opioids for acute pain indications, recommends indications for which new evidence-based guidelines should be developed, and recommends a future research agenda to inform and enable specialty organizations to develop and disseminate evidence-based clinical practice guidelines for prescribing opioids to treat acute pain indications. The recommendations of this study will assist professional societies, health care organizations, and local, state, and national agencies to develop clinical practice guidelines for opioid prescribing for acute pain. Such a framework could inform the development of opioid prescribing guidelines and ensure systematic and standardized methods for evaluating evidence, translating knowledge, and formulating recommendations for practice. |
| developing clinical practice guidelines: Clinical Practice Guidelines Institute of Medicine, Committee to Advise the Public Health Service on Clinical Practice Guidelines, 1990-02-01 The Alberta clinical practice guidelines program is supporting appropriate, effective and quality medical care in Alberta through promotion, development and implementation of evidence-based clinical practice guidelines. |
| developing clinical practice guidelines: Clinical Practice Guidelines in Mental Health Paula Whitty, Martin Eccles, 2018-12-14 This book describes the user-focused action evaluation approach for evaluating health programmes policies and changes. It shows that evidence for making decisions can be gathered using a broader range of methods than is usually recognised in healthcare. In asking 'evaluation for whom and for what?' the book defines validity of evidence in relation to usefulness as well as in terms of whether systematic methods were followed. Managers practitioners policy makers researchers and students will find this a practical and readable book. It gives the tools to make sense of an evaluation quickly as well as guidance for carrying one out and ensuring that evaluators gather evidence which can be used for better informed decisions. |
| developing clinical practice guidelines: Setting Priorities for Clinical Practice Guidelines Institute of Medicine, Committee on Methods for Setting Priorities for Guidelines Development, 1995-03-02 This book examines methods for selecting topics and setting priorities for clinical practice guideline development and implementation. Clinical practice guidelines are systematically defined statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances. In its assessment of processes for setting priorities, the committee considers the principles of consistency with the organization's mission, implementation feasibility, efficiency, utility of the results to the organization, and openness and defensibilityâ€a principle that is especially important to public agencies. The volume also examines the implications of health care restructuring for priority setting and topic selection, including the link between national and local approaches to guidelines development. |
| developing clinical practice guidelines: Knowing What Works in Health Care Institute of Medicine, Board on Health Care Services, Committee on Reviewing Evidence to Identify Highly Effective Clinical Services, 2008-05-29 There is currently heightened interest in optimizing health care through the generation of new knowledge on the effectiveness of health care services. The United States must substantially strengthen its capacity for assessing evidence on what is known and not known about what works in health care. Even the most sophisticated clinicians and consumers struggle to learn which care is appropriate and under what circumstances. Knowing What Works in Health Care looks at the three fundamental health care issues in the United States-setting priorities for evidence assessment, assessing evidence (systematic review), and developing evidence-based clinical practice guidelines-and how each of these contributes to the end goal of effective, practical health care systems. This book provides an overall vision and roadmap for improving how the nation uses scientific evidence to identify the most effective clinical services. Knowing What Works in Health Care gives private and public sector firms, consumers, health care professionals, benefit administrators, and others the authoritative, independent information required for making essential informed health care decisions. |
| developing clinical practice guidelines: Heart Failure Marvin A. Konstam, 1994 |
| developing clinical practice guidelines: Clinical Practice Guidelines We Can Trust Institute of Medicine, Board on Health Care Services, Committee on Standards for Developing Trustworthy Clinical Practice Guidelines, 2011-07-16 Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers. |
| developing clinical practice guidelines: Finding What Works in Health Care Institute of Medicine, Board on Health Care Services, Committee on Standards for Systematic Reviews of Comparative Effectiveness Research, 2011-07-20 Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research. |
| developing clinical practice guidelines: Users' Guides to the Medical Literature Gordon Guyatt, Drummond Rennie, Maureen O. Meade, Deborah J. Cook, 2008-03-01 The “essential” companion to the landmark Users' Guides to the Medical Literature - completely revised and updated! 5 STAR DOODY'S REVIEW! This second edition is even better than the original. Information is easier to find and the additional resources that will be available at www.JAMAevidence.com will provide readers with a one-stop source for evidence-based medicine.--Doody's Review Service Evidence-based medicine involves the careful interpretation of medical studies and its clinical application. And no resource helps you do it better-and faster-than Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice. This streamlined reference distills the most clinically-relevant coverage from the parent Users' Guide Manual into one highly-focused, portable resource. Praised for its clear explanations of detailed statistical and mathematical principles, The Essentials concisely covers all the basic concepts of evidence-based medicine--everything you need to deliver optimal patient care. It's a perfect at-a-glance source for busy clinicians and students, helping you distinguish between solid medical evidence and poor medical evidence, tailor evidence-based medicine for each patient, and much more. Now in its second edition, this carry-along quick reference is more clinically relevant--and more essential--than ever! FEATURES Completely revised and updated with all new coverage of the basic issues in evidence-based medicine in patient care Abundant real-world examples drawn from the medical literature are woven throughout, and include important related principles and pitfalls in using clinical research in patient care decisions Edited by over 60 internationally recognized editors and contributors from around the globe Also look for JAMAevidence.com, a new interactive database for the best practice of evidence based medicine. |
| developing clinical practice guidelines: WHO Handbook for Guideline Development World Health Organization, 2015-04-20 This handbook provides detailed instructions for guideline developers on the following topics: application of high quality methodology for guideline development using systematic search strategies, synthesis and quality assessment of the best available evidence to support the recommendations; appropriate collection and management of experts' declared conflict of interest; expert group composition including content experts, methodologists, target users, policy makers, with gender and geographical balance; instructions for the management of group process to achieve consensus among experts; standards for a transparent decision-making process, taking into consideration potential harms and benefits, end users values and preferences; developing plans for implementing and adapting guidelines; and minimum standards for reporting.--Publisher description. |
| developing clinical practice guidelines: Evidence-Based Clinical Practice in Nursing and Health Care Alan Pearson, John Field, Zoe Jordan, 2009-09-24 Evidence-Based Clinical Practice in Nursing and Healthcare examinesthe Joanna Briggs Institute model for evidence-based practice whichrecognises research, theory and practice as sources of evidence andtakes a practical approach to developing, implementing andevaluating practice, based on 'evidence' in its broadestsense. Evidence-based Clinical Practice in Nursing and Healthcareaddresses the nature of evidence in clinical practice, generatingand synthesising evidence, and transferring and utilising evidencein clinical practice. It describes the development of practiceinformation sheets and clinical guidelines and provides practicalguidance on the implementation of evidence-based practice and itsevaluation using clinical audit. |
| developing clinical practice guidelines: Conflict of Interest in Medical Research, Education, and Practice Institute of Medicine, Board on Health Sciences Policy, Committee on Conflict of Interest in Medical Research, Education, and Practice, 2009-09-16 Collaborations of physicians and researchers with industry can provide valuable benefits to society, particularly in the translation of basic scientific discoveries to new therapies and products. Recent reports and news stories have, however, documented disturbing examples of relationships and practices that put at risk the integrity of medical research, the objectivity of professional education, the quality of patient care, the soundness of clinical practice guidelines, and the public's trust in medicine. Conflict of Interest in Medical Research, Education, and Practice provides a comprehensive look at conflict of interest in medicine. It offers principles to inform the design of policies to identify, limit, and manage conflicts of interest without damaging constructive collaboration with industry. It calls for both short-term actions and long-term commitments by institutions and individuals, including leaders of academic medical centers, professional societies, patient advocacy groups, government agencies, and drug, device, and pharmaceutical companies. Failure of the medical community to take convincing action on conflicts of interest invites additional legislative or regulatory measures that may be overly broad or unduly burdensome. Conflict of Interest in Medical Research, Education, and Practice makes several recommendations for strengthening conflict of interest policies and curbing relationships that create risks with little benefit. The book will serve as an invaluable resource for individuals and organizations committed to high ethical standards in all realms of medicine. |
| developing clinical practice guidelines: JRCALC Clinical Guidelines 2019 Association of Ambulance Chief Executives, Joint Royal Colleges Ambulance Liaison Committee, 2019-08-05 The Joint Royal Colleges Ambulance Liaison Committee guidelines are the essential resource for paramedics. The 2019 edition of the book has been brought up to date with the latest evidence and developments in clinical practice. JRCALC combines expert advice with practical guidance to help paramedics in their challenging roles with the overall objective of improving patient care. Key updates are: •Resuscitation and cardiac arrest. The pathophysiology of cardiac arrest, checklist use and pulseless electrical activity is discussed extensively within the context of every day out of hospital practice. A new guideline on tracheostomy and laryngectomy is included, alongside clinical skills photographs. •Consent and patient confidentiality. The guideline is brought up to date with the Data Protection Act 2018 following the General Data Protection Regulations. •Mental health presentation: crisis, distress and disordered behaviour. A reviewed guideline supports the clinician with practical help on the assessment and management of different mental health illnesses. •Major, complex and high risk Incidents. A revision by the National Ambulance Resilience Unit covers poisons, rail incidents and police incapacitants. •New medicines are included: Activated charcoal, duodote and morphine sulfate for end of life care. •Other reviews and updates include: head injury, hyperventilation syndrome, stroke, respiratory illness in children and acute coronary syndrome. |
| developing clinical practice guidelines: Evidence Based Physical Therapy Linda Fetters, Julie Tilson, 2018-10-02 Improve outcomes through evidence-based therapy. This practical, easy-to-use guide uses a five-step process to show you how to find, appraise, and apply the research in the literature to meet your patient’s goals. You'll learn how to develop evidence-based questions specific to your clinical decisions and conduct efficient and effective searches of print and online sources to identify the most relevant and highest quality evidence. Then, you'll undertake a careful appraisal of the information; interpret the research; and synthesize the results to generate valid answers to your questions. And, finally, you'll use the Critically Appraised Topic (CAT) tool to communicate your findings. See what practitioners and students are saying about the previous edition… Great resource for applying evidence to practice. “The book is very clearly written with clinical examples, and in-depth questions. If you want a comprehensive book on statistics this is not the book for you, but it is an easily understandable introduction to physical therapy research which will help you to interpret the literature and apply it to your patients.” |
| developing clinical practice guidelines: Evidence-Based Surgery Achilles Thoma, Sheila Sprague, Sophocles H. Voineskos, Charles H. Goldsmith, 2019-03-25 The purpose of this book specifically is to teach surgeons (academic or community), surgical fellows and surgical residents regardless of the surgical specialty, the skills to appraise what they read in the surgical literature. Surgeons need to be able to understand what they read before applying the conclusions of a surgical article to their practice. As most surgeons do not have the extra training in health research methodology, understanding how the research was done, how to interpret the results and finally deciding to apply them to the patient level is indeed a difficult task. Chapters explain the methodological issues pertaining to the various study designs reported in the surgical literature. Most chapters begin with a clinical scenario with uncertain course of action with which most surgeons are struggling. Readers are taught how to search the literature for the best evidence that will answer the surgical problem under discussion. An identified article that seems relevant to the problem you are investigating can be appraised by addressing 3 key questions: 1). Is the study I am reading valid? 2). What are the results of this study? 3). Can I apply these results to my patients? While the primary goal of Evidence-Based Surgery is to teach surgeons how to appraise the surgical literature, an added benefit is that the concepts explained here may help research-minded surgeons produce higher quality research. |
| developing clinical practice guidelines: Evidence-Based Medicine Guidelines Duodecim Medical Publications, 2005-03-04 Evidence-Based Medicine Guidelines fills the demand for a handbook discussing the diagnosis and treatment of a wide range of diseases and conditions encountered by health care professionals. The title was first published in Finland by the Finnish Medical Society, where it is now considered to be the single most important support tool for the physicians' decision making in their daily work. What sets EBM Guidelines apart from competing books? Provides physicians with fast and easy access to practice guidelines based on the best available research evidence Covers practically all medical conditions encountered in general practice Developed by over 300 experienced general practitioners and specialists worldwide Includes both diagnostic and therapeutic guidelines, and recommendations on diagnostic tests and drug dosage Presented in a user-friendly format with self contained chapters based on clinical subjects Clear and concise explanations of all available evidence results in the guideline for treatment The strength of evidence is graded from A-D making this title a quick and easy reference whenever and wherever you need it! Assumes no prior knowledge of EBM or statistics - all the work of searching and appraisal has been done for you! Seeks to include guidelines where clinical evidence is incomplete or unavailable Contains full-colour photographs and tables throughout Easy-to-read and fast support at the point of care - EBM Guidelines: Summarises the best available evidence - Cochrane reviews - DARE abstracts - Clinical Evidence topics - original articles in medical journals - abstracts in the Health Technology Assessment Database - NHS Economic Evaluation Evaluates and grades the strength of all individual evidence from A (Strong research-based evidence) to D (No scientific evidence) Suggests guidelines based on clinical evidence. If clinical evidence is inadequate or missing, an expert panel evaluate all other available information and suggests the appropriate guideline With over 1000 problem-orientated or disease-specific guidelines including reference to evidence summaries for all guidelines, this title is the most extensive collection of guidelines for primary care today. Here are just a few examples of the raving reviews for Evidence-Based Medicine Guidelines: An excellent resource... quick to use, even during consultations...very helpful to check whether our preferred diagnostic and therapeutic methods are adequate...competent suggestions based on real evidence... —Heinz Bhend, PRIMARY CARE clinically useful answers...easy-to-read ...this resource is worth using... —Carl Heneghan, Centre for Evidence-Based Medicine, Oxford, UK, EVIDENCE-BASED MEDICINE Journal |
| developing clinical practice guidelines: Making Health Care Safer , 2001 This project aimed to collect and critically review the existing evidence on practices relevant to improving patient safety--P. v. |
| developing clinical practice guidelines: Preventive Health Services for Medicare Beneficiaries , 1990 |
| developing clinical practice guidelines: Code of Ethics for Nurses with Interpretive Statements American Nurses Association, 2001 Pamphlet is a succinct statement of the ethical obligations and duties of individuals who enter the nursing profession, the profession's nonnegotiable ethical standard, and an expression of nursing's own understanding of its commitment to society. Provides a framework for nurses to use in ethical analysis and decision-making. |
| developing clinical practice guidelines: Drug Information Patrick M. Malone, Karen L. Kier, John Stanovich, 2010-05-12 Extensive coverage of the Internet as a source of and distribution means for drug information, and detailed sections on evaluating medical literature from clinical trials Audience includes Pharmacists, Pharmacy students and Pharmacy schools Updated to include using PDAs for medication information Covers the ethical and legal aspects of drug information management Nothing else like it on the market |
| developing clinical practice guidelines: American Psychiatric Association Practice Guidelines American Psychiatric Association, 1996 The aim of the American Psychiatric Association Practice Guideline series is to improve patient care. Guidelines provide a comprehensive synthesis of all available information relevant to the clinical topic. Practice guidelines can be vehicles for educating psychiatrists, other medical and mental health professionals, and the general public about appropriate and inappropriate treatments. The series also will identify those areas in which critical information is lacking and in which research could be expected to improve clinical decisions. The Practice Guidelines are also designed to help those charged with overseeing the utilization and reimbursement of psychiatric services to develop more scientifically based and clinically sensitive criteria. |
| developing clinical practice guidelines: Developing Practice Guidelines for Social Work Intervention Aaron Rosen, Enola K. Proctor, 2003-11-26 This book bridges the gap between social work knowledge and empirically based practice. Although there is a significant need for the use of empirically tested and verified knowledge in social work practice, the empirical basis of support is nearly absent from practitioners'considerations as they make clinical decisions in routine practice. The authors advocate the development of readily available, accessible, and professionally sanctioned practice guidelines for use by practitioners, a necessity in the age of managed care and demands for greater accountability, effectiveness, and efficiency in practice. This book features a much-needed discussion of racial and ethnic differentials in relation to practice guidelines and on the relationship between practice guidelines and different aspects of service delivery. |
| developing clinical practice guidelines: Principles and Practice of Clinical Research John I. Gallin, Frederick P Ognibene, 2011-04-28 The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.*Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government |
| developing clinical practice guidelines: Meta-Analysis, Decision Analysis, and Cost-Effectiveness Analysis Diana B. Petitti, 2000 Public health and in health policy courses at the undergraduate and graduate level. |
| developing clinical practice guidelines: Powerful Medicines Jerry Avorn, M.D., 2008-12-10 If you believe that the latest blockbuster medication is worth a premium price over your generic brand, or that doctors have access to all the information they need about a drug’s safety and effectiveness each time they write a prescription, Dr. Jerry Avorn has some sobering news. Drawing on more than twenty-five years of patient care, teaching, and research at Harvard Medical School, he shares his firsthand experience of the wide gap in our knowledge of the effectiveness of one medication as compared to another. In Powerful Medicines, he reminds us that every pill we take represents a delicate compromise between the promise of healing, the risk of side effects, and an increasingly daunting price. The stakes on each front grow higher every year as new drugs with impressive power, worrisome side effects, and troubling costs are introduced. This is a comprehensive behind-the-scenes look at issues that affect everyone: our shortage of data comparing the worth of similar drugs for the same condition; alarming lapses in the detection of lethal side effects; the underuse of life-saving medications; lavish marketing campaigns that influence what doctors prescribe; and the resulting upward spiral of costs that places vital drugs beyond the reach of many Americans. In this engagingly written book, Dr. Avorn asks questions that will interest every consumer: How can a product judged safe by the Food and Drug Administration turn out to have unexpectedly lethal side effects? Why has the nation’s drug bill been growing at nearly 20 percent per year? How can physicians and patients pick the best medication in its class? How do doctors actually make their prescribing decisions, and why do those decisions sometimes go wrong? Why do so many Americans suffer preventable illnesses and deaths that proper drug use could have averted? How can the nation gain control over its escalating drug budget without resorting to rationing or draconian governmental controls? Using clinical case histories taken from his own work as a practitioner, researcher, and advocate, Dr. Avorn demonstrates the impressive power of the well-conceived prescription as well as the debacles that can result when medications are misused. He describes an innovative program that employs the pharmaceutical industry’s own marketing techniques to reduce use of some of the most overprescribed and overpriced products. Powerful Medicines offers timely and practical advice on how the nation can improve its drug-approval process, and how patients can work with doctors to make sure their prescriptions are safe, effective, and as affordable as possible. This is a passionate and provocative call for action as well as a compelling work of clear-headed science. |
| developing clinical practice guidelines: Clinical Guideline Development , 1990 |
| developing clinical practice guidelines: Painless Evidence-Based Medicine Antonio L. Dans, Leonila F. Dans, Maria Asuncion A. Silvestre, 2017-03-06 This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating an introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers. A simplified introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers Approaches learning from the vantage point of clinical questions on therapy, diagnosis, prognosis or harm rather than the framework of study designs Provides tables and boxed case studies throughout highlighting key topics, or difficult issues, in an easy to read manner Emphasizes applicability of EBM, encouraging readers to dissect the evidence and how results can be applied to individual patients with different circumstances, varying values and preferences New to the Second Edition are chapters on health screening, clinical practice guidelines, and major updates incorporating recommended trial criteria |
| developing clinical practice guidelines: Practice Guideline for the Treatment of Patients with Schizophrenia American Psychiatric Association, 1997 The American Psychiatric Association (APA) is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians. |
| developing clinical practice guidelines: Patient Safety in Emergency Medicine Pat Croskerry, Karen S. Cosby, 2009 With the increased emphasis on reducing medical errors in an emergency setting, this book will focus on patient safety within the emergency department, where preventable medical errors often occur. The book will provide both an overview of patient safety within health care—the 'culture of safety,' importance of teamwork, organizational change—and specific guidelines on issues such as medication safety, procedural complications, and clinician fatigue, to ensure quality care in the ED. Special sections discuss ED design, medication safety, and awareness of the 'culture of safety.' |
| developing clinical practice guidelines: WHO Global Report on Falls Prevention in Older Age World Health Organization, 2008 The WHO Falls Prevention for Active Ageing model provides an action plan for making progress in reducing the prevalence of falls in the older adult population. By building on the three pillars of falls prevention, the model proposes specific strategies for: 1. Building awareness of the importance of falls prevention and treatment; 2. Improving the assessment of individual, environmental, and societal factors that increase the likelihood of falls; and 3. For facilitating the design and implementation of culturally appropriate, evidence-based interventions that will significantly reduce the number of falls among older persons. The model provides strategies and solutions that will require the engagement of multiple sectors of society. It is dependent on and consistent with the vision articulated in the WHO Active Ageing Policy Framework. Although not all of the awareness, assessment, and intervention strategies identified in the model apply equally well in all regions of the world, there are significant evidence-based strategies that can be effectively implemented in all regions and cultures. The degree to which progress will be made depends on to the success in integrating falls prevention strategies into the overall health and social care agendas globally. In order to do this effectively, it is necessary to identify and implement culturally appropriate, evidence-based policies and procedures. This requires multi-sectoral, collaborations, strong commitment to public and professional education, interaction based on evidence drawn from a variety of traditional, complementary, and alternative sources. Although the understanding of the evidence-base is growing, there is much that is not yet understood. Thus, there is an urgent need for continued research in all areas of falls prevention and treatment in order to better understand the scope of the problem worldwide. In particular, more evidence of the cost-effectiveness of interconnections is needed to develop strategies that are most likely to be effective in specific setting and population sub-groups. |
| developing clinical practice guidelines: Models and Frameworks for Implementing Evidence-Based Practice Jo Rycroft-Malone, Tracey Bucknall, 2011-09-07 The Evidence-Based Nursing Series is co-published with Sigma Theta Tau International (STTI). The series focuses on implementing evidence-based practice in nursing and mirrors the remit of Worldviews on Evidence-Based Nursing, encompassing clinical practice, administration, research and public policy. Models and Frameworks for Implementing Evidence- Based Practice: Linking Evidence to Action looks at ways of implementing evidence gained through research and factors that influence successful implementation. It acknowledges the gap that exists between obtaining evidence and the practicalities of putting it into practice and provides direction to help to close this gap. This, the first book in the series, helps the reader to make decisions about the appropriateness of using various models and frameworks. A selection of models and frameworks are examined in detail including examples of their use in practice. The book concludes with an analysis and synthesis of the included models and frameworks. The models and frameworks that have been included are based on a number of criteria: that they are internationally recognised, have undergone widespread evaluation and testing, are transferable across different settings, and can be used by different disciplines. Models and frameworks include: Stetler Model Ottowa Model of Research Use IOWA model of evidence-based practice Advancing Research and Clinical Practice through Close Collaboration (ARCC) model Dobbins’ dissemination and use of research evidence for policy and practice framework Joanna Briggs Institute model Knowledge to Action framework Promoting Action on Research Implementation in Health Services (PARIHS) Key Points: Includes an overview of implementation issues and the use of theory and frameworks in implementing evidence into practice Chapters are written by the developers of the model or framework Each chapter provides background on an implementation model or framework, suitable applications, underlying theory and examples of use Each chapter examines strengths and weaknesses of each model alongside barriers and facilitators for its implementation |
| developing clinical practice guidelines: Clinical Epidemiology Patrick S. Parfrey, Brendan J. Barrett, 2016-10-08 Focusing on improving the diagnosis, prognosis, and management of human disease, this book takes on the issues of research design, measurement, and evaluation which are critical to clinical epidemiology. This second edition of Clinical Epidemiology: Practice and Methods opens with how best to frame a clinical research question, the ethics associated with doing a research project in humans, and the definition of various biases that occur in clinical research. From there, it continues by examining issues of design, measurement, and analysis associated with various research designs, including determination of risk in longitudinal studies, assessment of therapy in randomized controlled clinical trials, and evaluation of diagnostic tests, and then delves into the more specialized area of clinical genetic research, before concluding with basic methods used in evidence-based decision making including critical appraisal, aggregation of multiple studies using meta-analysis, health technology assessment, clinical practice guidelines, development of health policy, translational research, how to utilize administrative databases, and knowledge translation. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and practical advice to ensure real world success. Comprehensive and authoritative, Clinical Epidemiology: Practice and Methods, Second Edition is intended to educate researchers on how to undertake clinical research and should be helpful not only to medical practitioners but also to basic scientists who want to extend their work to humans, to allied health professionals interested in scientific evaluation, and to trainees in clinical epidemiology. |
| developing clinical practice guidelines: Diagnostic and Statistical Manual of Mental Disorders (DSM-5) American Psychiatric Association, 2021-09-24 |
| developing clinical practice guidelines: Prevention and Treatment of Pressure Ulcers National Pressure Ulcer Advisory Panel (U.S.), 2014-09-30 This Clinical Practice Guideline presents recommendations and summarizes the supporting evidence for pressure ulcer prevention and treatment. The first edition was developed as a four year collaboration between the National Pressure Ulcer Advisory Panel (NPUAP) and the European Pressure Ulcer Advisory Panel (EPUAP). In this second edition of the guideline, the Pan Pacific Pressure Injury Alliance (PPPIA) has joined the NPUAP and EPUAP. This edition of the guideline has been developed over a two year period to provide an updated review of the research literature, extend the scope of the guideline and produce recommendations that reflect the most recent evidence. It provides a detailed analysis and discussion of available research, critical evaluation of the assumptions and knowledge in the field, recommendations for clinical practice, a description of the methodology used to develop the guideline and acknowledgements of the 113 experts formally involved in the development process. |
| developing clinical practice guidelines: Clinical Guidelines in Primary Care Amelie Hollier, 2016 |
| developing clinical practice guidelines: Setting Priorities for Clinical Practice Guidelines Institute of Medicine, Committee on Methods for Setting Priorities for Guidelines Development, 1995-04-02 This book examines methods for selecting topics and setting priorities for clinical practice guideline development and implementation. Clinical practice guidelines are systematically defined statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances. In its assessment of processes for setting priorities, the committee considers the principles of consistency with the organization's mission, implementation feasibility, efficiency, utility of the results to the organization, and openness and defensibilityâ€a principle that is especially important to public agencies. The volume also examines the implications of health care restructuring for priority setting and topic selection, including the link between national and local approaches to guidelines development. |
| developing clinical practice guidelines: Prevention and Treatment of Pressure Ulcers/injuries , 2019 |
352 Synonyms & Antonyms for DEVELOPING - Thesaurus.com
Find 352 different ways to say DEVELOPING, along with antonyms, related words, and example sentences at Thesaurus.com.
DEVELOPING Synonyms: 163 Similar and Opposite Words - Merriam-Webster
Synonyms for DEVELOPING: evolving, unfolding, progressing, growing, elaborating, proceeding, emerging, maturing; Antonyms of DEVELOPING: losing, abandoning, forsaking, deserting, …
What is another word for developing - WordHippo
Find 2,929 synonyms for developing and other similar words that you can use instead based on 31 separate contexts from our thesaurus.
DEVELOPING Definition & Meaning | Dictionary.com
Developing definition: undergoing development; growing; evolving.. See examples of DEVELOPING used in a sentence.
DEVELOPING | English meaning - Cambridge Dictionary
DEVELOPING definition: 1. A developing country or area of the world is poorer and has less advanced industries, especially…. Learn more.
developing adjective - Definition, pictures, pronunciation and …
Definition of developing adjective from the Oxford Advanced Learner's Dictionary. (of a country, society, etc.) poor, and trying to make its industry and economic system more advanced. …
developing - WordReference.com Dictionary of English
to cause to grow or expand: to develop one's muscles. to elaborate or expand in detail: to develop a theory. evolve.
Developing - definition of developing by The Free Dictionary
Define developing. developing synonyms, developing pronunciation, developing translation, English dictionary definition of developing. adj. Having a relatively low level of industrial …
DEVELOPING definition and meaning | Collins English Dictionary
If you talk about developing countries or the developing world, you mean the countries or the parts of the world that are poor and have few industries.
developing - Wiktionary, the free dictionary
Jan 2, 2025 · developing. In the process of development. a developing foetus; Of a country: becoming economically more mature or advanced; becoming industrialized.
352 Synonyms & Antonyms for DEVELOPING - Thesaurus.com
Find 352 different ways to say DEVELOPING, along with antonyms, related words, and example sentences at Thesaurus.com.
DEVELOPING Synonyms: 163 Similar and Opposite Words - Merriam-Webster
Synonyms for DEVELOPING: evolving, unfolding, progressing, growing, elaborating, proceeding, emerging, maturing; Antonyms of DEVELOPING: losing, abandoning, forsaking, deserting, …
What is another word for developing - WordHippo
Find 2,929 synonyms for developing and other similar words that you can use instead based on 31 separate contexts from our thesaurus.
DEVELOPING Definition & Meaning | Dictionary.com
Developing definition: undergoing development; growing; evolving.. See examples of DEVELOPING used in a sentence.
DEVELOPING | English meaning - Cambridge Dictionary
DEVELOPING definition: 1. A developing country or area of the world is poorer and has less advanced industries, especially…. Learn more.
developing adjective - Definition, pictures, pronunciation and …
Definition of developing adjective from the Oxford Advanced Learner's Dictionary. (of a country, society, etc.) poor, and trying to make its industry and economic system more advanced. …
developing - WordReference.com Dictionary of English
to cause to grow or expand: to develop one's muscles. to elaborate or expand in detail: to develop a theory. evolve.
Developing - definition of developing by The Free Dictionary
Define developing. developing synonyms, developing pronunciation, developing translation, English dictionary definition of developing. adj. Having a relatively low level of industrial …
DEVELOPING definition and meaning | Collins English Dictionary
If you talk about developing countries or the developing world, you mean the countries or the parts of the world that are poor and have few industries.
developing - Wiktionary, the free dictionary
Jan 2, 2025 · developing. In the process of development. a developing foetus; Of a country: becoming economically more mature or advanced; becoming industrialized.
