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| diagram of a homeostasis pathway: Anatomy and Physiology J. Gordon Betts, Peter DeSaix, Jody E. Johnson, Oksana Korol, Dean H. Kruse, Brandon Poe, James A. Wise, Mark Womble, Kelly A. Young, 2013-04-25 |
| diagram of a homeostasis pathway: A Textbook of Science for the Health Professions Barry G. Hinwood, 1997 To keep abreast with current developments in medicine, members of the health care team require a firm grasp of science to cope with changes in technology and understanding of the mechanisms of body function. This is in addition to developing a range of interpersonal and communication skills. There are sections covering biology, chemistry, physics, nutrition, biochemistry, medical microbiology and physiology. Highly illustrated, it includes over a hundred applications and examples to assist the reader in relating science to health care. Throughout, the text is divided into units containing a common theme, and each chapter contains a list of objectives and a summary. |
| diagram of a homeostasis pathway: Thyroid Hormone Metabolism Georg Hennemann, 1986 |
| diagram of a homeostasis pathway: Regulation of Tissue Oxygenation, Second Edition Roland N. Pittman, 2016-08-18 This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved. |
| diagram of a homeostasis pathway: Anatomy & Physiology Lindsay Biga, Devon Quick, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Matern, Katie Morrison-Graham, Jon Runyeon, 2019-09-26 A version of the OpenStax text |
| diagram of a homeostasis pathway: Phosphate Metabolism Shaul Massry, 2013-11-21 We present to our readers the proceedings of the Second International Workshop on Phosphate. A short account of the history of the effort led to the Phosphate Workshops is appro priate and can be of interest to the reader. The idea for Phosphate Workshops was born in the early days of November, 1974. One of us (S. G. M. ) suggested the thought to a group of scientists gathered for a luncheon in one of the attrac tive small restaurants in Weisbaden, Germany. The purpose of the workshop was to bring together interested scientists to discuss the newer developments and the recent advances in the field of phosphate metabolism and the other related minerals. An Organizing Committee made of Shaul G. Massry (USA), Louis V. Avioli (USA), Philippe Bordier (France), Herbert Fleisch (Switzerland), and Eduardo Slatopolsky (USA) was formed. The First Workshop was held in Paris during June 5-6, 1975 and was hosted by Dr. Philippe Bordier. Its proceeding was already published. The Second Workshop took place in Heidelberg during June 28-30, 1976 and was hosted by Dr. Eberhard Ritz. Both of these workshops were extremely successful scientific endeavors, and the need for them was demonstrated by the great interest they generated among the scientific community. The Or ganizing Committee, therefore, decided to continue with the tradi tion to hold additional Workshops annually or every other year. |
| diagram of a homeostasis pathway: Introduction to Cellular Biophysics, Volume 2 Armin Kargol, 2019-12-13 All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What the cells consists of? Where are its organelles? What function each organelle fulfils? From a chemists’ point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, some of the fundamental questions are about the physical movement of all these molecules between organelles within the cell, their exchange with the extracellular medium, as well as electrical phenomena resulting from such transport. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and various electrical effects, and that in turn leads to biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfill its function as a part of a larger organ or organism. The first volume of this book is an inventory of physical transport processes occurring in cells while this second volume provides a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes. |
| diagram of a homeostasis pathway: Growth Hormone in Adults Anders Juul, Jens O. L. Jorgensen, 2000-04-27 This revised new edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the resulting disorders from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject; this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and aging and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. This volume is the most authoritative, comprehensive, and detailed account available and will be an essential source of reference for all endocrinologists. |
| diagram of a homeostasis pathway: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy. |
| diagram of a homeostasis pathway: Tissue-Specific Cell Signaling Joana Vieira Silva, Maria João Freitas, Margarida Fardilha, 2020-05-29 Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. |
| diagram of a homeostasis pathway: The Potential Effects and Mechanisms of Chinese Traditional Medicine on Bone Homeostasis and Remodeling Jun Liu, Bo Liu, Xiaoqin Wu, Qi Wang, 2023-09-20 Osteoporosis is a systemic skeletal disease, strongly affecting postmenopausal women and characterized by an increased risk of bone fragility and a decrease in bone mass. Bone homeostasis requires a balance between bone-forming osteoblasts and bone-resorbing osteoclasts. When this balance is impaired, normal bone remodelling cannot keep bone mass stable, leading to osteopenia and osteoporosis. About 30–50% of all women in the world suffer from fractures due to osteoporosis throughout their lives. The treatments include improving metabolic abnormalities through complementary and alternative therapies, drug application and surgical therapy for the management of overweight, obesity and hormone metabolism disorder. Chinese traditional medicine has been increasingly considered as an effective therapy for osteoporosis. A series of formulae, herbs and natural products have been indicated for their effects in the prevention and treatment of osteoporosis, such as Liu-Wei-Di-Huang Wan (formula), Morindae Officinalis Radix (herb), Longspur epimedium glycoside (natural product). However, the mechanisms of action remain largely unexplored. |
| diagram of a homeostasis pathway: The Core Concepts of Physiology Joel Michael, William Cliff, Jenny McFarland, Harold Modell, Ann Wright, 2017-02-20 This book offers physiology teachers a new approach to teaching their subject that will lead to increased student understanding and retention of the most important ideas. By integrating the core concepts of physiology into individual courses and across the entire curriculum, it provides students with tools that will help them learn more easily and fully understand the physiology content they are asked to learn. The authors present examples of how the core concepts can be used to teach individual topics, design learning resources, assess student understanding, and structure a physiology curriculum. |
| diagram of a homeostasis pathway: Minimally Invasive Glaucoma Surgery Chelvin C. A. Sng, Keith Barton, 2021 The book is provided open access under a CC BY 4.0 license. This book covers all aspects of minimally invasive glaucoma surgery (MIGS) and provides detailed information on each MIGS device, including its mechanism of action; patient selection; implantation techniques; post-operative management; and a review of the existing literature. Step-by-step descriptions are provided for the surgical technique used in implanting each MIGS device, accompanied by clear photographs of each surgical stage. Other areas covered include intra-operative gonioscopy (with tips on optimising the view of the anterior chamber angle) and the management of the intra-operative and post-operative complications. Essential information on the anatomy and physiology of the different aqueous outflow pathways is also included. A separate chapter addresses the introduction of MIGS globally, including the consideration of different reimbursement environments and the different types of glaucoma, e.g. angle closure glaucoma. This book will assist both glaucoma surgeons and general ophthalmologists in overcoming the learning curve involved in performed MIGS, by providing valuable and practical clinical pearls. |
| diagram of a homeostasis pathway: Neuroscience in the 21st Century Donald W. Pfaff, Nora D. Volkow, 2016-10-27 Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike. |
| diagram of a homeostasis pathway: MRCOG Part One Alison Fiander, Baskaran Thilaganathan, 2016-10-13 A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination. |
| diagram of a homeostasis pathway: Biochemical, Physiological, and Molecular Aspects of Human Nutrition - E-Book Martha H. Stipanuk, Marie A. Caudill, 2012-03-30 Covering advanced nutrition with a comprehensive, easy-to-understand approach, Biochemical, Physiological, and Molecular Aspects of Human Nutrition, 3rd Edition focuses on the biology of human nutrition at the molecular, cellular, tissue, and whole-body levels. It addresses nutrients by classification, and describes macronutrient function from digestion to metabolism. This edition includes the new MyPlate dietary guide and recommendations from the Dietary Guidelines for Americans 2010, plus coverage of the historical evolution of nutrition and information on a wide range of vitamins, minerals, and other food components. In Biochemical, Physiological, and Molecular Aspects of Human Nutrition, lead authors Martha H. Stipanuk and Marie A. Caudill are joined by a team of nutrition experts in providing clear, concise, coverage of advanced nutrition. - 55 expert contributors provide the latest information on all areas of the nutrition sciences. - Nutrition Insight boxes discuss hot topics and take a closer look at basic science and everyday nutrition. - Clinical Correlation boxes show the connection between nutrition-related problems and their effects on normal metabolism. - Food Sources boxes summarize and simplify data from the USDA National Nutrient Database on the amount and types of foods needed to reach the recommended daily allowances for vitamins and minerals. - DRIs Across the Life Cycle boxes highlight the latest data from the Institute of Medicine on dietary reference intakes for vitamins and minerals, including coverage of infants, children, adult males and females, and pregnant and lactating women. - Life Cycle Considerations boxes highlight nutritional processes or concepts applicable to individuals of various ages and in various stages of the life span. - Thinking Critically sections within boxes and at the end of chapters help in applying scientific knowledge to real-life situations. - Lists of common abbreviations provide an overview of each chapter's content at a glance. - Comprehensive cross-referencing by chapters and illustrations is used throughout. - Current references and recommended readings connect you to nutrition-related literature and provide additional tools for research. - Coverage of the USDA's MyPlate dietary guide reflects today's new approach to diet and nutrition. - Recommendations outlined in the Dietary Guidelines for Americans 2010 are incorporated throughout the book. - Updated format features more subheadings, tables, and bullets, making it easier to learn and recall key points. - Updates of key chapters and boxes reflect significant changes within the fields of nutrition, biology, molecular biology, and chemistry. - NEW illustrations simplify complex biochemical, physiological, and molecular processes and concepts. |
| diagram of a homeostasis pathway: Zookeeping Mark D. Irwin, John B. Stoner, Aaron M. Cobaugh, 2013-12-09 As species extinction, environmental protection, animal rights, and workplace safety issues come to the fore, zoos and aquariums need keepers who have the technical expertise and scientific knowledge to keep animals healthy, educate the public, and create regional, national, and global conservation and management communities. This textbook offers a comprehensive and practical overview of the profession geared toward new animal keepers and anyone who needs a foundational account of the topics most important to the day-to-day care of zoo and aquarium animals. The three editors, all experienced in zoo animal care and management, have put together a cohesive and broad-ranging book that tackles each of its subjects carefully and thoroughly. The contributions cover professional zookeeping, evolution of zoos, workplace safety, animal management, taxon-specific animal husbandry, animal behavior, veterinary care, public education and outreach, and conservation science. Using the newest techniques and research gathered from around the world, Zookeeping is a progressive textbook that seeks to promote consistency and the highest standards within global zoo and aquarium operations. |
| diagram of a homeostasis pathway: The Hypothalamus-Pituitary-Adrenal Axis , 2008-09-12 The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. - Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle - Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later |
| diagram of a homeostasis pathway: The Endocrine Pancreas Ellis Samols, 1991 |
| diagram of a homeostasis pathway: Transcription Regulation - Brain Development and Homeostasis - A Finely Tuned and Orchestrated Scenario in Physiology and Pathology Estela Maris Muñoz, Veronica Martinez Cerdeño, Flavio S. J. De Souza, Martin Fredensborg Rath, 2022-02-21 |
| diagram of a homeostasis pathway: Encyclopedia of Pain G.F. Gebhart, Robert F. Schmidt, 2013-11-18 The Encyclopedia of Pain includes more than 3,000 entries and provides clear, detailed and up-to-date coverage of the current state of research, and treatment of pain. In addition, detailed essays provide in-depth information on all aspects of nociception and pain, including substrates, causes, pathophysiology, symptoms and signs, diagnoses and treatment. A thousand color figures enhance understanding of this too-little-understood topic. The book is available in print, in online only form, or in a print-online bundle. |
| diagram of a homeostasis pathway: Oncogenic PI3KT/Akt/mTOR Pathway Alterations, ROS Homeostasis, Targeted Cancer therapy and drug resistance Rozangela Curi Pedrosa, Karina Felipe, Danilo Wilhelm Filho, 2024-02-23 The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway is an important signaling route that regulates several cell functions. PI3K/AKT/mTOR pathway is a crossroad of cell death and survival, playing a pivotal role in multiple interconnected cell signaling mechanisms implicated in cell metabolism, growth and proliferation, apoptosis, and angiogenesis. Disruptions in the Akt‑regulated pathways and alterations in PTEN expression are associated to Reactive oxygen species (ROS) homeostasis and different types of cancer. Genomic studies have shown that activating mutations in oncogenes as well as inactivating mutations in tumor suppressor genes are present across a variety of malignancies, including constitutive activation of the PI3K/AKT/mTOR pathway. The regulation of the Akt signaling pathway renders multiple challenges and valuable therapeutic targets. The discovery process of Akt, PDK1 and mTOR synthetic and natural products as inhibitors or immune checkpoint inhibitors using various strategies, could led to the identification of small molecule inhibitors with great selectivity, low side‑effects and also low toxicity regarding drug development. |
| diagram of a homeostasis pathway: Mathematical Modeling of the Immune System in Homeostasis, Infection and Disease Gennady Bocharov, Burkhard Ludewig, Andreas Meyerhans, Vitaly Volpert, 2020-02-24 The immune system provides the host organism with defense mechanisms against invading pathogens and tumor development and it plays an active role in tissue and organ regeneration. Deviations from the normal physiological functioning of the immune system can lead to the development of diseases with various pathologies including autoimmune diseases and cancer. Modern research in immunology is characterized by an unprecedented level of detail that has progressed towards viewing the immune system as numerous components that function together as a whole network. Currently, we are facing significant difficulties in analyzing the data being generated from high-throughput technologies for understanding immune system dynamics and functions, a problem known as the ‘curse of dimensionality’. As the mainstream research in mathematical immunology is based on low-resolution models, a fundamental question is how complex the mathematical models should be? To respond to this challenging issue, we advocate a hypothesis-driven approach to formulate and apply available mathematical modelling technologies for understanding the complexity of the immune system. Moreover, pure empirical analyses of immune system behavior and the system’s response to external perturbations can only produce a static description of the individual components of the immune system and the interactions between them. Shifting our view of the immune system from a static schematic perception to a dynamic multi-level system is a daunting task. It requires the development of appropriate mathematical methodologies for the holistic and quantitative analysis of multi-level molecular and cellular networks. Their coordinated behavior is dynamically controlled via distributed feedback and feedforward mechanisms which altogether orchestrate immune system functions. The molecular regulatory loops inherent to the immune system that mediate cellular behaviors, e.g. exhaustion, suppression, activation and tuning, can be analyzed using mathematical categories such as multi-stability, switches, ultra-sensitivity, distributed system, graph dynamics, or hierarchical control. GB is supported by the Russian Science Foundation (grant 18-11-00171). AM is also supported by grants from the Spanish Ministry of Economy, Industry and Competitiveness and FEDER grant no. SAF2016-75505-R, the “María de Maeztu” Programme for Units of Excellence in R&D (MDM-2014-0370) and the Russian Science Foundation (grant 18-11-00171). |
| diagram of a homeostasis pathway: Astrocytic-neuronal-astrocytic Pathway Selection for Formation and Degradation of Glutamate/GABA Leif Hertz, Tiago B. Rodrigues, 2014-04-30 Endocrinological research early recognized the importance of intercellular interactions and realized the importance of glutamatergic and GABAergic signaling. In turn this signalling depends on elaborate interactions between astrocytes and neurons, without which neurons would be unable to produce, reuse and metabolize transmitter glutamate and GABA. Details of these subjects are described in this Research Topic by key investigators in this field. It focuses on the intricate and extremely swift pathway producing these amino acid transmitters from glucose in brain but also discusses difficulties in determining expression of some of the necessary genes in astrocytes and related processes in pancreatic islets. However, it does not discuss how closely associated astrocytes and neurons are anatomically, enabling these interactions. This is elegantly shown in this cover image, kindly provided by Professor Andreas Reichenbach (University of Leipzig, Germany). |
| diagram of a homeostasis pathway: Metabolic Regulation in Mammals David Gibson, Robert A. Harris, 2003-09-02 Metabolic Regulation in Mammals presents the basic principles of metabolic control, based on investigations conducted during the past twenty years. It explains the impact of recent advances in cell biology, molecular biology and genetics on the field. Beginning with the basic concepts, this text covers all angles of metabolic regulation, including blood caloric homeostasis, cardiac and skeletal muscle, adipose tissue, and liver metabolism. Review questions, summary sections and worked examples help break down the complexity of the subject and allow the reader to review the principles and concepts presented. Details of metabolic pathways are provided for each body system, with accompanying charts to provide the reader with an overall perspective. This text is ideal for undergraduates across a range of biological and health science disciplines, particularly those taking one or two semester courses in metabolic regulation. |
| diagram of a homeostasis pathway: The Pineal Gland I. Nir, R. J. Reiter, R. J. Wurtman, 2015-01-07 |
| diagram of a homeostasis pathway: Endocrinology of the Gut Frank P. Brooks, William Y. Chey, 1974 |
| diagram of a homeostasis pathway: Mathematical modeling in energy homeostasis, appetite control and food intake with a special attention to ghrelin Jorge Guerra Pires, 2017-03-18 The elegant ‘interconnected mechanisms’ by which the gastrointestinal (GI) tract regulates food intake are a marvel of biology, but the redundancy (e.g., several hormones seem to have effects in food intake) of both GI (by means of hormones) and central nervous system (CNS, by means of satiety/satiation signals) pathways governing energy homeostasis poses formidable challenges for scientists trying to take a clear glimpse of this machinery, e.g. for designing anti-obesity and alike pharmaceuticals. In essence, notwithstanding the astonishing advancements made over the past few decades in unscrambling many of the molecular pathways involved in energy (homeostasis) regulation, a rather cloudy understanding of “how all the pieces fit together to function as an integrated system” is what can be found for the most part in the scientific community; we discuss that in part II of the work, in a single chapter divided in several sections for numerous imperative hormones, e.g. cholecystokinin. The current work is divided into three parts: part I is regarding fundamentals of physiology and mathematical modeling employed all over the work; part II is more generic and concerns several hormones (what we have called a “web of hormones”) and part III (divided into three chapters) is more specific, concerning a single hormone (i.e., ghrelin). The core of the work is part III, and to a certain extent part II, bearing mind we provide a literature review based on papers scattered/dispersed all over the medical science literature. The main objective of this work is proposing a mathematical model for ghrelin dynamics (Figure 70), a model centered on the gastrointestinal tract (stomach + small intestine, a two-compartment model), with daily-like dynamics, short-term dynamics; and, simultaneously, proposing a prototype for a systems biology like model (igure 40), a model based on numerous hormones, for understanding mathematically food intake/bodyweight control. Ghrelin is a quite powerful orexigenic hormone discovered in the late 1990s that controls appetite and energy homeostasis, alongside leptin and other hormones still to be investigated in depth by the medical sciences literature. Accordingly, we provide a (simple) mathematical model, consisting of a set of ordinary differential equations detailing ghrelin dynamics combined to gastrointestinal signals due to meals. Numerical simulations are able to replicate in silico available data from the literature; additionally, we were able to fit a reduced version of the basal model to experimental data. The model is developed as a module for a bigger potential multi-compartmental structure, detailing food and energy homeostasis within a sort of a web of hormones (see part II and the last chapter of part III). The present contribute is to recommend a primary mathematical model for ghrelin dynamics centered in the gastrointestinal tract, with potentiality to be applied also for postabsorptive states, left mainly as future works. We go on with the model by presenting mainly two variations, further unfolding is left as future endeavor: tastants and stochastic version. We test several optimization routines for the parameter estimation procedure, hybrid algorithms (global + local search), for parameter estimation, based on data published for humans (three meals a day). For all the routines, the best is a hybrid composed of simulating annealing as global search and pattern search as local search. In the objective function (sum of the squared errors, SSE), we apply artificial neural networks (a two-layer feedforward neural network) for generating new data from the data already published, a strategy adopted to increase the data set. In the last part of the chapter about ghrelin modeling (part III), we propose several prototypes for future works based on the basal models; the model used for parameter estimation is a “minimal/reduced” model; we also provide discussions and future works for the minimal model and parameter estimation. Key-words. Ghrelin; leptin; mathematical modelling; food intake; appetite; parameter estimation. |
| diagram of a homeostasis pathway: Cellular Stress and Inflammation: How the Immune System Drives Tissue Homeostasis Fabrizio Antonangeli, Francesca Velotti, Ola Grimsholm, Marianna Nicoletta Rossi, 2021-05-10 |
| diagram of a homeostasis pathway: Store-Operated Calcium Channels , 2013-07-24 Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject |
| diagram of a homeostasis pathway: The Pentose Phosphate Pathway Terry Wood, 2012-12-02 The Pentose Phosphate Pathway aims to explore the pentose phosphate cycle and the practical techniques applied in its investigation. The main focus of the book is the pentose phosphate cycle in animals as well as microorganisms, and does not discuss the one related to photosynthesis. The book covers the formulation of the pathway, its types, and its alternative formulations; the preparation, processes, and analysis of the pathway; and the enzymes involved. Also covered in the book are the intermediates in intact cells and tissues; distribution of enzymes among different tissues and species; the operation, regulation, and overall control of the pathway; and the clinical, nutritional, and metabolic aspects of the pathway. The text is recommended for biologists and biochemists who would like to understand further the pentose phosphate pathway and the processes related to it. |
| diagram of a homeostasis pathway: Abscisic Acid in Plants , 2019-11-21 Abscisic Acid in Plants, Volume 92, the latest release in the Advances in Botanical Research series, is a compilation of the current state-of-the-art on the topic. Chapters in this new release comprehensively describe latest knowledge on how ABA functions as a plant hormone. They cover topics related to molecular mechanisms as well as the biochemical and chemical aspects of ABA action: hormone biosynthesis, catabolism, transport, perception, signaling in plants, seeds and in response to biotic and abiotic stresses, hormone evolution and chemical biology, and much more. - Presents the latest release in the Advances in Botanical Research series - Provides an Ideal resource for post-graduates and researchers in the plant sciences, including plant physiology, plant genetics, plant biochemistry, plant pathology, and plant evolution - Contains contributions from internationally recognized authorities in their respective fields |
| diagram of a homeostasis pathway: Energetics, Kinetics, and Life George Tyler Miller, 1971 |
| diagram of a homeostasis pathway: The Physiology of Inflammation – The Final Common Pathway to Disease Alexandrina Ferreira Mendes, Maria Teresa Cruz, Oreste Gualillo, 2019-02-20 Chronic diseases are increasingly recognized as involving low grade inflammation, that is, a self-perpetuating tissue response to stress caused by exogenous or endogenous triggers, that progressively evokes danger-associated molecular pattern release, ultimately driving tissue damage and loss of function. This response is frequently unapparent clinically, thus the designation low grade. This eBook comprises nineteen reviews and original articles that provide the most updated knowledge on the causes and roles of this inflammatory response in a variety of diseases and conditions. The editorial that precedes these articles not only summarizes each one, but provides a broader interpretation of the role of inflammation in health and a variety of disease conditions, the underlying mechanisms and the targets more promising for therapy. Finally, it also highlights the most relevant and emerging research topics that are already shaping future directions for the development of more fine-tuned and innovative therapies. |
| diagram of a homeostasis pathway: The nutritional immunological effects and mechanisms of chemical constituents from the homology of medicine and food Peng Ji, Yi Wu, Guiyan Yang, 2023-07-20 |
| diagram of a homeostasis pathway: Hormonal Regulation of Growth Herwig Frisch, 1989 |
| diagram of a homeostasis pathway: The Roles of Immune Cell Homeostasis in Cancer Research and Therapeutic Response Zhijie Xu, Jianhua Zhou, Abhimanyu Thakur, Kui Zhang, Zhi-Yao He, 2023-07-03 |
| diagram of a homeostasis pathway: Jasmonic Acid Pathway in Plants Kenji Gomi, 2020-04-30 The plant hormone jasmonic acid (JA) and its derivative, an amino acid conjugate of JA (jasmonoyl isoleucine, JA-Ile), are signaling compounds involved in the regulation of defense and development in plants. The number of articles studying on JA has dramatically increased since the 1990s. JA is recognized as a stress hormone that regulates the plant response to biotic stresses such as herbivore and pathogen attacks, as well as abiotic stresses such as wounding and ultraviolet radiation. Recent studies have remarkably progressed the understanding of the importance of JA in the life cycle of plants. JA is directly involved in many physiological processes, including stamen growth, senescence, and root growth. JA regulates production of various metabolites such as phytoalexins and terpenoids. Many regulatory proteins involved in JA signaling have been identified by screening for Arabidopsis mutants. However, much more remains to be learned about JA signaling in other plant species. This Special Issue, “Jasmonic Acid Pathway in Plants”, contains 5 review and 15 research articles published by field experts. These articles will help with understanding the crucial roles of JA in its response to the several environmental stresses and development in plants. |
| diagram of a homeostasis pathway: Biology for AP ® Courses Julianne Zedalis, John Eggebrecht, 2017-10-16 Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences. |
| diagram of a homeostasis pathway: Neurobiological circuit function and computation of the serotonergic and related systems KongFatt Wong-Lin, Kae Nakamura, 2015-02-24 Serotonin is one of the oldest neurotransmitters in evolutionary terms, and the serotonergic system is complex and multifaceted. Serotonin-producing neurons in the raphe nuclei provide serotonin innervations throughout various parts of the brain, modulating cellular excitability and network properties of targeted brain areas, and regulating mood, cognition and behavior. Dysfunctions of the serotonergic system are implicated in neuropsychiatric disorders including depression, schizophrenia, and drug abuse. Although the system has been studied for many years, an integrative account of its functions and computational principles remains elusive. This is partly attributed to the high variability and heterogeneity in terms of neuronal properties and receptor types, and its extensive connections with other brain regions. This Frontiers Research Topic e-book is a collection of recent experimental and computational work and approaches at multiple scales that provide the latest information regarding the integrated functions of the serotonergic system. The contributed papers include a variety of experimental and computational work, and human clinical studies. |
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draw.io. Clearing Cached version 27.1.4... OK Update Start App Start App
Draw.io
Editing the diagram from page view may cause data loss. Please edit the Confluence page first and then edit the diagram. confConfigSpacePerm=Note: If you recently migrated from DC app, …
Flowchart Maker & Online Diagram Software
The Software will not transmit Data Diagram to any person other than the third party service provider to perform the tasks referred to in clause 3, and to you. The Diagram Data transmitted …
Flowchart Maker & Online Diagram Software
The diagram can only be edited from the page that owns it. linkToDiagram=Link to Diagram changedBy=Changed By lastModifiedOn=Last modified on searchResults=Search Results …
Flowchart Maker & Online Diagram Software
draw.io is free online diagram software. You can use it as a flowchart maker, network diagram software, to create UML online, as an ER diagram tool, …
Open Diagram - Draw.io
Missing parent window
draw.io
Pick OneDrive File. Create OneDrive File. Pick Google Drive File. Create Google Drive File. Pick Device File
Getting Started - Draw.io
Learn how to import diagram files, rename or remove tabs, and use the draw.io diagram editor. Add a diagram to a conversation in Microsoft …
Flowchart Maker & Online Diagram Software
Create flowcharts and diagrams online with this easy-to-use software.
