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| experimental biology and medicine: Proceedings of the Society for Experimental Biology and Medicine Society for Experimental Biology and Medicine (New York, N.Y.), 1921 List of members in each volume. |
| experimental biology and medicine: An Introduction to the Study of Experimental Medicine Claude Bernard, 1927 First English translation of the classical work on the principles of physiological investigation in life sciences. |
| experimental biology and medicine: Proceedings of the Society for Experimental Biology and Medicine Society for Experimental Biology and Medicine, Klaus Unna, Walter Marx, Ludwig Halberstaedter, David Nachmansohn, 1943 |
| experimental biology and medicine: The Rise of Experimental Biology Peter L. Lutz, 2002-04-19 Peter Lutz, PhD, brilliantly traverses the major milestones along the evolutionary path of biomedicine from earliest recorded times to the dawn of the 20th century. With an engaging narrative that will have you turning just one more page well into the night, this book revealingly demonstrates just how the modern scientific method has been shaped by the past. Along the way the reader is treated to some delightfully obscure anecdotes and a treasure trove of rich illustrations that chronicle the tortuous history of biomedical developments, ranging from the bizarre and amusing to the downright macabre. The reader will also be introduced to the major ideas shaping contemporary physiology and the social context of its development, and also gain an understanding of how advances in biological science have occasionally been improperly used to satisfy momentary social or political needs. |
| experimental biology and medicine: Experimental Design for Biologists David J. Glass, 2007 The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan. |
| experimental biology and medicine: Kisspeptin Signaling in Reproductive Biology Alexander S. Kauffman, Jeremy T. Smith, 2013-04-02 Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis. |
| experimental biology and medicine: Beyond the Molecular Frontier National Research Council, Division on Earth and Life Studies, Board on Chemical Sciences and Technology, Committee on Challenges for the Chemical Sciences in the 21st Century, 2003-03-19 Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future. |
| experimental biology and medicine: Taurine 5 John B. Lombardini, Stephen W. Schaffer, Junichi Azuma, 2012-12-06 The Taurine Symposium- Taurine: Beginning the 21'' Century- was held September 20-23, 2002, on the beautiful island of Kauai in Hawaii. The headquarters of the meeting was the Radisson Kauai Beach Resort. This international meeting was attending by approximately 80 individuals from 23 nations and 4 continents. Seventy-five papers were presented either as platform presentations or poster presentations. Taurine, first isolated from ox bile in 1827 by Tiedemann and Gmelin and named in 1838 by Demarcay, became of significant scientific interest in 1968 when the first extensive review article was published by Jacobsen and Smith. Interest in taurine grew exponentially after 1975 when the first taurine symposium was organized by Ryan Huxtable in Tucson, Arizona. Since that date, taurine symposia have been held approximately every two years held in various cities and resort areas around the world. Taurine investigators have had the privilege of attending these scientific meetings on three continents - Asia, Europe, and North America. Since the initial meeting in 1975, a central question addressed during many of the symposia has been: What is physiological, pharmacological, nutritional, and pathological role of taurine?. Although taurine has been established as an important osmolyte, it appears to affect many other biological processes. However, the exact mechanism(s) by which taurine acts has not yet been definitively answered. In Kauai, the patticipants discussed many topics and asked many questions regarding the role and actions of taurine. |
| experimental biology and medicine: Isotope labeling in Biomolecular NMR Hanudatta S. Atreya, 2012-10-18 NMR spectroscopy has undergone a revolution in recent years with the advent of several new methods overcoming the problems of sensitivity and resolution. Recent developments in biotechnology have made it easier and economical to introduce 13C, 15N and 2H into proteins and nucleic acids. At the same time, there has been an explosion in the number of NMR experiments that utilize such isotope labeled samples. Thus, a combination of isotopic labeling and multidimensional, multinuclear NMR has opened up new avenues for structural studies of proteins, nucleic acids and their complexes. This book will focus on recent developments in isotope labeling methods for structural studies of small molecules, peptides, proteins and nucleic acids. The aim of the book is to serve as a compendium of isotope labeling for the biomolecular NMR community providing comprehensive coverage of the existing methods and latest developments along with protocols and practical hints on the various experimental aspects. The book will cover a wide range of topics in isotope labeling under one title including emerging areas of metabolonomics and solid state NMR. |
| experimental biology and medicine: Proceedings of the Society for Experimental Biology and Medicine , 1975 |
| experimental biology and medicine: Statistical Methods in Agriculture and Experimental Biology Roger Mead, 2017-11-22 The third edition of this popular introductory text maintains the character that won worldwide respect for its predecessors but features a number of enhancements that broaden its scope, increase its utility, and bring the treatment thoroughly up to date. It provides complete coverage of the statistical ideas and methods essential to students in agriculture or experimental biology. In addition to covering fundamental methodology, this treatment also includes more advanced topics that the authors believe help develop an appreciation of the breadth of statistical methodology now available. The emphasis is not on mathematical detail, but on ensuring students understand why and when various methods should be used. New in the Third Edition: A chapter on the two simplest yet most important methods of multivariate analysis Increased emphasis on modern computer applications Discussions on a wider range of data types and the graphical display of data Analysis of mixed cropping experiments and on-farm experiments |
| experimental biology and medicine: Autophagy: Biology and Diseases Weidong Le, 2020-07-15 This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine |
| experimental biology and medicine: Proceedings of the Society for Experimental Biology and Medicine , 1996-05 List of members in each volume. |
| experimental biology and medicine: Biomechanics in Animal Behaviour R.W. Blake, P. Domenici, 2021-05-30 Biomechanics in Animal Behaviour offers a unique approach by integrating fully the fields of animal behaviour and biomechanics. It demonstrates how an understanding of biomechanical issues is an important part of evaluating and predicting animal behaviour. The book examines how behaviour is determined and/or constrained by biomechanical variables such as hydrodynamics, aerodynamics, kinematics, and the mechanical properties of biomaterials. |
| experimental biology and medicine: Mast Cell Biology Alasdair M. Gilfillan, Dean Metcalfe, 2011-06-28 The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease. |
| experimental biology and medicine: Medical Cell Biology Steven R. Goodman, 2007-11-26 Medical Cell Biology, Third Edition, focuses on the scientific aspects of cell biology important to medical students, dental students, veterinary students, and prehealth undergraduates. With its National Board-type questions, this book is specifically designed to prepare students for this exam. The book maintains a concise focus on eukaryotic cell biology as it relates to human and animal disease, all within a manageable 300-page format. This is accomplished by explaining general cell biology principles in the context of organ systems and disease. This updated version contains 60% new material and all new clinical cases. New topics include apoptosis and cell death from a neural perspective; signal transduction as it relates to normal and abnormal heart function; and cell cycle and cell division related to cancer biology. - 60% New Material! - New Topics include: - Apoptosis and cell dealth from a neural perspective - Signal transduction as it relates to normal and abnormal heart function - Cell cycle and cell division related to cancer biology - All new clinical cases - Serves as a prep guide to the National Medical Board Exam with sample board-style questions (using Exam Master(R) technology): www.exammaster.com - Focuses on eukaryotic cell biology as it related to human disease, thus making the subject more accessible to pre-med and pre-health students |
| experimental biology and medicine: Systems Biomedicine Edison T. Liu, Douglas A. Lauffenburger, 2009-09-17 Systems biology is a critical emerging field that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon. - Organized to reflect the important distinguishing characteristics of systems strategies in experimental biology and medicine - Provides precise and comprehensive measurement tools for constructing a model of the system and tools for defining complexity as an experimental dependent variable - Includes a thorough discussion of the applications of quantitative principles to biomedical problems |
| experimental biology and medicine: Experimental Techniques in Bacterial Genetics Stanley R. Maloy, 1990 |
| experimental biology and medicine: The Thalassaemia Syndromes David J. Weatherall, J. B. Clegg, 2008-04-30 In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in the laboratory or clinical setting, particularly in areas where thalassaemia is common either in the native population or in immigrant communities. The fourth edition has been both updated and re-organized. Three new chapters have been added on the link between alpha-thalassaemia and mental retardation, on avoidance and population control and on global epidemiology. Considerable emphasis is placed on molecular pathology reflecting the huge burst of information to have come out of this field in the last few years. |
| experimental biology and medicine: Muscle Biophysics Rassier Dilson J.E, 2010-09-08 Muscle contraction has been the focus of scientific investigation for more than two centuries, and major discoveries have changed the field over the years. Early in the twentieth century, Fenn (1924, 1923) showed that the total energy liberated during a contraction (heat + work) was increased when the muscle was allowed to shorten and perform work. The result implied that chemical reactions during contractions were load-dependent. The observation underlying the “Fenn effect” was taken to a greater extent when Hill (1938) published a pivotal study showing in details the relation between heat production and the amount of muscle shortening, providing investigators with the force-velocity relation for skeletal muscles. Subsequently, two papers paved the way for the current paradigm in the field of muscle contraction. Huxley and Niedergerke (1954), and Huxley and Hanson (1954) showed that the width of the A-bands did not change during muscle stretch or activation. Contraction, previously believed to be caused by shortening of muscle filaments, was associated with sliding of the thick and thin filaments. These studies were followed by the classic paper by Huxley (1957), in which he conceptualized for the first time the cross-bridge theory; filament sliding was driven by the cyclical interactions of myosin heads (cross-bridges) with actin. The original cross-bridge theory has been revised over the years but the basic features have remained mostly intact. It now influences studies performed with molecular motors responsible for tasks as diverse as muscle contraction, cell division and vesicle transport. |
| experimental biology and medicine: Research in Medical and Biological Sciences Petter Laake, Haakon Breien Benestad, Bjorn R. Olsen, 2015-06-05 Research in Medical and Biological Sciences covers the wide range of topics that a researcher must be familiar with in order to become a successful biomedical scientist. Perfect for aspiring as well as practicing professionals in the medical and biological sciences, this publication discusses a broad range of topics that are common yet not traditionally considered part of formal curricula, including philosophy of science, ethics, statistics, and grant applications. The information presented in this book also facilitates communication across conventional disciplinary boundaries, in line with the increasingly multidisciplinary nature of modern research projects. - Covers the breadth of topics that a researcher must understand in order to be a successful experimental scientist - Provides a broad scientific perspective that is perfect for students with various professional backgrounds - Contains easily accessible, concise material about diverse methods - Includes extensive online resources such as further reading suggestions, data files, statistical tables, and the StaTable application package - Emphasizes the ethics and statistics of medical and biological sciences |
| experimental biology and medicine: Evolutionary Systems Biology Orkun S. Soyer, 2012-07-23 The book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework. An evolutionary approach might allow understanding the significance of observed diversity, uncover “evolutionary design principles” and extend predictions made in model organisms to others. In addition, evolutionary systems biology can generate new insights into the adaptive landscape by combining molecular systems biology models and evolutionary simulations. This insight can enable the development of more detailed mechanistic evolutionary hypotheses. |
| experimental biology and medicine: Hypospadias and Genital Development Laurence S. Baskin, 2004 This book focuses on the current basic science research of hypospadias and genital development. Congenital anomalies of the genitalia are the second most common birth abnormality besides congenital heart defects. Genital anomalies come in many varieties with the most common abnormality being hypospadias. The etiology of hypospadias remains unknown and the incidence is doubling in western countries with no definable explanation. It therefore seems especially germane to study this common congenital anomaly with a baseline incidence of 1/125-250 newborn males. |
| experimental biology and medicine: The Emotional Cerebellum Michael Adamaszek, Mario Manto, Dennis J. L. G. Schutter, 2022-07-29 Emotions represent a critical aspect of daily life in humans. Our understanding of the mechanisms of regulation of emotions has increased exponentially these last two decades. This book evaluates the contribution of the cerebellum to emotion. It outlines the current clinical, imaging and neurophysiological findings on the role of the cerebellum in key aspects of emotional processing and its influence on motor and cognitive function and social behavior. In the first section, the reader is introduced to the contributions of the cerebellum to various emotion domains, from emotion perception and recognition to transmission and encoding. Subsequent chapters provide a comprehensive picture of the neurophysiology and topography of emotion in the cerebellum and illustrate the convergence of theoretical and empirical research. Additional chapters address the cerebellum's involvement in emotional learning, emotional pain, emotional aspects of body language and perception, and its relations to social cognition including morality, music, and art. Finally, neuropsychiatric aspects of the cerebellum's influence on mood disorders and the current state of therapeutic options, including noninvasive stimulation approaches, complete the overview. This is the first book summarizing the current state of knowledge on the contribution of the cerebellum to important aspects of emotion. It is an essential reference for students, trainees, neuroscientists, researchers, and clinicians in neuroscience, neurology, neurosurgery and psychology involved in the study of emotions. The authors are renowned scientists in the field of cerebellar research. |
| experimental biology and medicine: Pediatric Gender Assignment Stephen A. Zderic, Douglas A. Canning, Michael C. Carr, Howard McC. Snyder III, 2003-01-31 This book represents the proceedings from a conference that took place in Dallas in the spring of 1999 which was entitled Pediatric Gender Assignment - A Critical Reappraisal. Some participants rightfully argued that the conference really focused on the issue of pediatric gender assignment, and that reassignment was not applied in most cases. Their comments were reflected in the title of this monograph. This multidisciplinary meeting was sponsored by a conference grant from the National Institutes of Health, and a broad inquiry into this complex topic took place from many points of view. Basic scientists offered insight into mechanisms of sexual differentiation of the gonads, physical phenotype and imprinting of the central nervous system. Endocrinologists reviewed their experience in diagnosis and management, surgeons described traditional as well as innovative approaches, and there was strong representation from the ethical and behavioral sciences. In putting together such a panel, it was essential that we identify a cast of speakers who could address their viewpoints with strong convictions, and yet not let their passions render the meeting counter productive. We were not disappointed. While many differing points of view were firmly expressed by the panelists and audience, all viewpoints were accorded the respect they deserved. The concept behind the meeting and this book really originated in 1997 shortly after Diamond and Sigmundson published their long term follow up study of the John/Joan case. |
| experimental biology and medicine: Biomedical Optical Imaging James G. Fujimoto, Daniel Farkas, 2009-04-22 Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity. |
| experimental biology and medicine: Artificial Intelligence in Medicine David Riaño, Szymon Wilk, Annette ten Teije, 2019-06-19 This book constitutes the refereed proceedings of the 17th Conference on Artificial Intelligence in Medicine, AIME 2019, held in Poznan, Poland, in June 2019. The 22 revised full and 31 short papers presented were carefully reviewed and selected from 134 submissions. The papers are organized in the following topical sections: deep learning; simulation; knowledge representation; probabilistic models; behavior monitoring; clustering, natural language processing, and decision support; feature selection; image processing; general machine learning; and unsupervised learning. |
| experimental biology and medicine: Hepatic Encephalopathy Roger F. Butterworth, Gilles Pomier Layrargues, 2012-12-06 |
| experimental biology and medicine: Coronavirus Disease - COVID-19 Nima Rezaei, 2021-05-10 In December 2019, the world witnessed the occurrence of a new coronavirus to humanity. The disease spread quickly and became known as a pandemic globally, affecting both society and the health care system, both the elderly and young groups of people, and both the men’s and women’s groups. It was a universal challenge that immediately caused a surge in scientific research. Be a part of a world rising in fighting against the pandemic, the Coronavirus Disease - COVID-19 was depicted in the early days of the pandemic, but updated by more than 200 scientists and clinicians to include many facets of this new infectious pandemic, including i, characteristics, ecology, and evolution of coronaviruses; ii, epidemiology, genetics, and pathogenesis (immune responses and oxidative stress) of the disease; iii, diagnosis, prognosis, and clinical manifestations of the disease in pediatrics, geriatrics, pregnant women, and neonates; iv, challenges of co-occurring the disease with tropical infections, cardiovascular diseases, hypertension, and cancer and to the settings of dentistry, hematology, ophthalmology, and pharmacy; v, transmission, prevention, and potential treatments, ranging from supportive ventilator support and nutrition therapy to potential virus- and host-based therapies, immune-based therapies, photobiomodulation, antiviral photodynamic therapy, and vaccines; vi, the resulting consequences on social lives, mental health, education, tourism industry and economy; and vii, multimodal approaches to solve the problem by bioinformatic methods, innovation and ingenuity, globalization, social and scientific networking, interdisciplinary approaches, and art integration. We are approaching December 2020 and the still presence of COVID-19, asking us to call it COVID (without 19). |
| experimental biology and medicine: Neural Crest Induction and Differentiation Jean-Pierre Saint-Jeannet, 2006-08-28 Written by an international panel of recognized leaders in the field, Neural Crest Induction and Differentiation discusses all aspects of modern neural crest biology from its evolutionary significance to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Abundant color figures enhance the text providing clear and attractive illustrations of central issues and concepts. |
| experimental biology and medicine: Cell and Molecular Biology of Wood Formation Rodney A. Savidge, J. R. Barnett, Richard Napier, 2000 The application of modern molecular biology techniques is providing new insight into wood formation and the seasonal nature of secondary growth in perennial woody plant species. Extensively illustrated, this new book provides a comprehensive and critical overview of current understanding about the biology of wood formation, with a focus on the development, regulation and biochemistry of cambial growth supplemented by additional considerations of the fundamental factors determining forest productivity, wood quality and heartwood formation. |
| experimental biology and medicine: Lung Cancer and Personalized Medicine Aamir Ahmad, Shirish Gadgeel, 2015-12-14 This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer—statistics and epidemiology of lung cancer—along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer—immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies. |
| experimental biology and medicine: Experimental Design and Data Analysis for Biologists Gerald Peter Quinn, Michael J. Keough, 2002-03-21 Regression, analysis of variance, correlation, graphical. |
| experimental biology and medicine: The Australian Journal of Experimental Biology and Medical Science , 1924 |
| experimental biology and medicine: Proceedings of the Society for Experimental Biology and Medicine Society for Experimental Biology and Medicine (New York, N.Y.), 1997 List of members in each volume. |
| experimental biology and medicine: Use of Laboratory Animals in Biomedical and Behavioral Research National Research Council, Institute of Medicine, Institute for Laboratory Animal Research, Commission on Life Sciences, Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research, 1988-02-01 Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action. |
| experimental biology and medicine: Exploring the Biological Contributions to Human Health Institute of Medicine, Board on Health Sciences Policy, Committee on Understanding the Biology of Sex and Gender Differences, 2001-07-02 It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers. |
| experimental biology and medicine: Statistical Design and Analysis of Biological Experiments Hans-Michael Kaltenbach, 2021-04-15 This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research. It covers the most common aspects of experimental design such as handling multiple treatment factors and improving precision. In addition, it addresses experiments with large numbers of treatment factors and response surface methods for optimizing experimental conditions or biotechnological yields. The book emphasizes the estimation of effect sizes and the principled use of statistical arguments in the broader scientific context. It gradually transitions from classical analysis of variance to modern linear mixed models, and provides detailed information on power analysis and sample size determination, including ‘portable power’ formulas for making quick approximate calculations. In turn, detailed discussions of several real-life examples illustrate the complexities and aberrations that can arise in practice. Chiefly intended for students, teachers and researchers in the fields of experimental biology and biomedicine, the book is largely self-contained and starts with the necessary background on basic statistical concepts. The underlying ideas and necessary mathematics are gradually introduced in increasingly complex variants of a single example. Hasse diagrams serve as a powerful method for visualizing and comparing experimental designs and deriving appropriate models for their analysis. Manual calculations are provided for early examples, allowing the reader to follow the analyses in detail. More complex calculations rely on the statistical software R, but are easily transferable to other software. Though there are few prerequisites for effectively using the book, previous exposure to basic statistical ideas and the software R would be advisable. |
| experimental biology and medicine: Basic Science Methods for Clinical Researchers Morteza Jalali, Francesca Yvonne Louise Saldanha, Mehdi Jalali, 2017-03-31 Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science. - Serves as a helpful guide for clinical researchers who lack a conventional science background - Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms - Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data - Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP) |
| experimental biology and medicine: Piezo Channels , 2017-07-17 Piezo Channels, Volume 79, the latest volume in the Current Topics in Membranes series provides the necessary membrane research to assist readers in discovering the current state of a particular field and future directions. New chapters in the updated volume include A Tour de Force: The Discovery, Properties, and Function of Piezo Channels, Piezo1 Channels in Vascular Development and the Sensing of Shear Stress, the Origin of the Force: The Force-From-Lipids Principle Applied to Piezo Channels, Genetic Diseases of PIEZO1 and PIEZO2 Dysfunction, and The Structural Basis for Sensing by the Piezo1 Protein. Users of this series will find an up-to-date presentation of the current knowledge in the field of Piezo Channels. - Written by leading experts in the field - Contains original material, both textual and illustrative, that make it a very relevant reference - Presented in a very comprehensive manner - Ideal reference for both researchers in the field and general readers who will find this book to be relevant and up-to-date |
The section in Anatomy/Pathology of Experimental Biology …
What topics are we interested in publishing in Experimental Biology and Medicine? The Anatomy/Pathology section invites reports of original research that provide novel insights …
Experimental Biology 2015 - Nature
Experimental Biology is an annual meeting that brings together researchers from dozens of life-science disciplines, from laboratory to translational to clinical investigation.
The Importance of the Omega-6/Omega-3 Fatty Acid Ratio in ...
Society for Experimental Biology and Medicine April 11, 2008 Artemis P. Simopoulos, M.D. President, The Center for Genetics, Nutrition and Health, Washington DC This article contains …
Advances in Experimental Medicine and Biology
ehensively the major advances in these areas. Contributions from this meeting are presented in the book entitled “Biochemical Role of Cell surface Macromolecules” comprising 22 chapters …
Experimental Biology and Medicine
Using the tools of molecular biology and genetics, research is defining the mechanisms by which genes influence nutrient absorption, metabolism and ex-cretion, taste perception, and degree …
Experimental & Molecular Medicine - Nature
Experimental & Molecular Medicine is a medical research journal devoted to publishing the latest developments in translational research and the recent discoveries in the biomedical field.
Advances in Experimental Medicine and Biology - Springer
Advances in Experimental Medicine and Biology presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in meeting …
Advances in Experimental Medicine and Biology
Breathing is performed by the rhythmic contraction of respiratory muscles. It main-tains homeostasis of the organism by taking in the oxygen necessary to live and work and by …
Advances in Experimental Medicine and Biology - Springer
Advances in Experimental Medicine and Biology presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents …
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science …
Advances in Experimental Medicine and Biology
Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene …
Advances in Experimental Medicine and Biology
information in this important research field. Some of the novel topics to be addressed included: what is the relationship between normal and malignant phenotypes? what is the role of stem …
Advances in Experimental Medicine and Biology
A. El Idrissi and W.J. L Amoreaux (eds.), Taurine 8 , Advances in Experimental 3 Medicine and Biology 775, DOI 10.1007/978-1-4614-6130-2_1, © Springer Science+Business Media New …
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Volume 719 Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann …
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
Bruley’s studies on oxygen transport to tissue started in 1962 with a prominent medical doctor, Dr. Melvin H. Knisely (Medical School of South Carolina), who was interested in the influence of …
Advances in Experimental Medicine and Biology
Advances in Experimental Medicine and Biology presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents …
Advances in Experimental Medicine - Springer
Advances in Experimental Medicine and Biology presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents …
The section in Anatomy/Pathology of Experimental Biology …
What topics are we interested in publishing in Experimental Biology and Medicine? The Anatomy/Pathology section invites reports of original research that provide novel insights …
Experimental Biology 2015 - Nature
Experimental Biology is an annual meeting that brings together researchers from dozens of life-science disciplines, from laboratory to translational to clinical investigation.
The Importance of the Omega-6/Omega-3 Fatty Acid Ratio in ...
Society for Experimental Biology and Medicine April 11, 2008 Artemis P. Simopoulos, M.D. President, The Center for Genetics, Nutrition and Health, Washington DC This article contains …
Advances in Experimental Medicine and Biology
ehensively the major advances in these areas. Contributions from this meeting are presented in the book entitled “Biochemical Role of Cell surface Macromolecules” comprising 22 chapters …
Experimental Biology and Medicine
Using the tools of molecular biology and genetics, research is defining the mechanisms by which genes influence nutrient absorption, metabolism and ex-cretion, taste perception, and degree …
Experimental & Molecular Medicine - Nature
Experimental & Molecular Medicine is a medical research journal devoted to publishing the latest developments in translational research and the recent discoveries in the biomedical field.
Advances in Experimental Medicine and Biology - Springer
Advances in Experimental Medicine and Biology presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in meeting …
Advances in Experimental Medicine and Biology
Breathing is performed by the rhythmic contraction of respiratory muscles. It main-tains homeostasis of the organism by taking in the oxygen necessary to live and work and by …
Advances in Experimental Medicine and Biology - Springer
Advances in Experimental Medicine and Biology presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents …
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science …
Advances in Experimental Medicine and Biology
Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene …
Advances in Experimental Medicine and Biology
information in this important research field. Some of the novel topics to be addressed included: what is the relationship between normal and malignant phenotypes? what is the role of stem …
Advances in Experimental Medicine and Biology
A. El Idrissi and W.J. L Amoreaux (eds.), Taurine 8 , Advances in Experimental 3 Medicine and Biology 775, DOI 10.1007/978-1-4614-6130-2_1, © Springer Science+Business Media New …
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Volume 719 Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann …
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
Bruley’s studies on oxygen transport to tissue started in 1962 with a prominent medical doctor, Dr. Melvin H. Knisely (Medical School of South Carolina), who was interested in the influence of …
