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| frank starling law of the heart: Physics, Pharmacology and Physiology for Anaesthetists Matthew E. Cross, Emma V. E. Plunkett, 2014-03-06 A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams. |
| frank starling law of the heart: Basic Physiology for Anaesthetists David Chambers, Christopher Huang, Gareth Matthews, 2019-07-25 Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource. |
| frank starling law of the heart: Starling’s Law of The Heart Revisited Henk Keurs, M.I.M Noble, 2012-12-06 H. E. D. J. TER KEURS & M. I. M. NOBLE The Starling's Law of the Heart and The Frank-Starling Mechanism have long been the cornerstone of cardiac mechanical physiology. It is often forgotten that Frank and Starling carried out fundamentally different exper iments. Frankl measured the isovolumic pressure developed by frog heart at different volumes. He therefore discovered the pressure-volume-volume rela tionship which depends directly on the force-length relationship of the 2 sarcomeres. Starling ,3 studied cardiac shortening as manifest by cardiac output and its relationship to end-diastolic conditions as manifest by right atrial pressure. Thus he was studying the ability of cardiac muscle to shorten more at a given load from a greater initial length. Starling in the promulga 4 tions of his law implied a common mechanism for these two phenomena and spoke of the energy liberated being a function of initial muscle fiber length. However, there has been much confusion about the interrelationship between the two different aspects studied by Frank and Starling. The 1960s saw the era of isolated cardiac muscle mechanics, beginning with 5 the paper of Abbott and Mommaerts. Whole muscle length-tension relations were equated with sarcomere-length-tension relations by fixation of muscle at a particular point on the curve and determination of sarcomere length by electronmicroscopy. |
| frank starling law of the heart: Cardiovascular Physiology Concepts Richard E. Klabunde, 2020-12-01 Praised for its concise coverage, this highly accessible monograph lays a foundation for understanding the underlying concepts of normal cardiovascular function and offers a welcome alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Clear explanations, ample illustrations and engaging clinical cases and problems provide the perfect guidance for self-directed learning and prepare you to excel in clinical practice. |
| frank starling law of the heart: Oxford Dictionary of Sports Science and Medicine Michael Kent, 2006-12-01 The Oxford Dictionary of Sports Science and Medicine provides comprehensive and authoritative definitions of nearly 8000 sports science and sports medicine terms. All major areas are covered, including exercise psychology, sports nutrition, biomechanics, anatomy, sports sociology, training principles and techniques and sports injury and rehabilitation The dictionary will be an invaluable aid to students, coaches, athletes and anyone wanting instant access to the scientific principles, anatomical structures, and physiological, sociological and psychological processes that affect sporting performance. It will also be of interest to the general reader interested in sports science and medicine terminology. |
| frank starling law of the heart: A Life of Ernest Starling John Henderson, 2013-11-18 Ernest Starling (1866-1927) was pre-eminent in the golden age of British Physiology. His name is usually associated with his Law of the Heart,” but his discovery of secretin (the first hormone whose mode of action was explained) and his work on capillaries were more important contributions. He coined the word 'hormone' one hundred years ago. His analysis of capillary function demonstrated that equal and opposite forces move across the capillary wall--an outward (hydrostatic) force and an inward (osmotic) force derived from plasma proteins. |
| frank starling law of the heart: Anesthesiology Core Review Brian Freeman, Jeffrey Berger, 2014-07-06 A rigorous, high-yield review for the new ABA Part 1: BASIC Examination The year 2014 marks the beginning of a new phase in board certification for anesthesiology residents in the United States. The Part 1 exam is now split into two written examinations: Basic and Advanced. Anesthesiology. Residents who are unable to pass the Basic examination will not be allowed to finish their training. That's why this book is a true must read for every anesthesiology resident. It is the single best way to take the stress out of this make-or-break exam, focus your study on nearly 200 must-know topics found on the board exam outline, and identify your areas of strength and weakness. Written by program directors with many years of board examination advising experience, Anesthesiology Core Review Part One: BASIC Exam is designed to be the cornerstone of your study preparation. Each chapter of Anesthesiology Core Review succinctly summarizes key concepts in basic science and clinical anesthesia practice. Space is conveniently provided throughout the book to add notes from other study resources. Anesthesiology Core Review Part One: BASIC Exam is logical divided into four sections: Basic Science Clinical Sciences Organ-Based Sciences Special Issues in Anesthesiology (covering important topics such as professionalism and licensure, ethics, and patient safety) With its expert authorship and concise yet thorough coverage, Anesthesiology Core Review Part One: BASIC Exam is biggest step you can take to assure effective preparation for the new ABA BASIC Examination. |
| frank starling law of the heart: Cardiovascular Hemodynamics for the Clinician George A. Stouffer, 2017-03-06 Cardiovascular Hemodynamics for the Clinician, 2nd Edition, provides a useful, succinct and understandable guide to the practical application of hemodynamics in clinical medicine for all trainees and clinicians in the field. Concise handbook to help both practicing and prospective clinicians better understand and interpret the hemodynamic data used to make specific diagnoses and monitor ongoing therapy Numerous pressure tracings throughout the book reinforce the text by demonstrating what will be seen in daily practice Topics include coronary artery disease; cardiomyopathies; valvular heart disease; arrhythmias; hemodynamic support devices and pericardial disease New chapters on TAVR, ventricular assist devices, and pulmonic valve disease, expanded coverage of pulmonary hypertension, fractional flow reserve, heart failure with preserved ejection fraction and valvular heart disease Provides a basic overview of circulatory physiology and cardiac function followed by detailed discussion of pathophysiological changes in various disease states |
| frank starling law of the heart: Dilated Cardiomyopathy Gianfranco Sinagra, Marco Merlo, Bruno Pinamonti, 2019-05-17 This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease. |
| frank starling law of the heart: Essential Clinical Anesthesia Review Linda S. Aglio, Robert W. Lekowski, Richard D. Urman, 2015-01-08 This concise, evidence-based board review book, organized according to the ABA keyword list, covers all the fundamental concepts needed to pass written and re-certification board examinations. Each chapter begins with a case scenario or clinical problem from everyday practice, followed by concise discussion and clinical review questions and answers. Discussion progresses logically from preoperative assessment and intraoperative management to postoperative pain management, enhancing the reader's knowledge and honing diagnostic and clinical management skills. New guidelines and recently developed standards of care are also covered. Serving as a companion to the popular textbook Essential Clinical Anesthesia, this resourceful work reflects the clinical experiences of anesthesia experts at Harvard Medical School as well as individually known national experts in the field of anesthesiology. This practical review is an invaluable resource for anesthesiologists in training and practice, whether studying for board exams or as part of continuing education and ABA recertification. |
| frank starling law of the heart: Cardiovascular Physiology E-Book Achilles J. Pappano, Withrow Gil Wier, 2012-12-20 Cardiovascular Physiology gives you a solid understanding of how the cardiovascular system functions in both health and disease. Ideal for your systems-based curriculum, this title in the Mosby Physiology Monograph Series explains how the latest concepts apply to real-life clinical situations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Get clear, accurate, and up-to-the-minute coverage of the physiology of the cardiovascular system. Master the material easily with objectives at the start of each chapter; self-study questions, summaries, and key words and concepts. Grasp the latest concepts in vascular, molecular, and cellular biology as they apply to cardiovascular function, thanks to molecular commentaries in each chapter. Apply information to clinical situations with the aid of clinical commentaries and highlighted clinical vignettes throughout. |
| frank starling law of the heart: Control of Cardiac Output David Young, 2010-01-01 Although cardiac output is measured as the flow of blood from the left ventricle into the aorta, the system that controls cardiac output includes many other components besides the heart itself. The heart’s rate of output cannot exceed the rate of venous return to it, and therefore, the factors governing venous return are primarily responsible for control of output from the heart. Venous return is affected by its pressure gradient and resistance to flow throughout the vascular system. The pressure gradient for venous return is a function of several factors including the blood volume flowing through the system, the unstressed vascular volume of the circulatory system, its capacitance, mean systemic pressure, and right atrial pressure. Resistance to venous return is the sum of total vascular resistance from the aortic valve to the right atrium. The sympathetic nervous system and vasoactive circulating hormones affect short-term resistance, whereas local tissue blood flow autoregulatory mechanisms are the dominant determinants of long-term resistance to venous return. The strength of contraction of the heart responds to changes in atrial pressure driven by changes in venous return, with small changes in atrial pressure eliciting large changes in strength of contraction, as described by the Frank–Starling mechanism. In addition, the autonomic nervous system input to the heart alters myocardial pumping ability in response to cardiovascular challenges. The function of the cardiovascular system is strongly affected by the operation of the renal sodium excretion–body fluid volume–arterial pressure negative feedback system that maintains arterial blood pressure at a controlled value over long periods. The intent of this volume is to integrate the basic knowledge of these cardiovascular system components into an understanding of cardiac output regulation. Table of Contents: Introduction / Venous Return / Cardiac Function / Integrated Analysis of Cardiac Output Control / Analysis of Cardiac Output Regulation by Computer Simulation / Analysis of Cardiac Output Control in Response to Challenges / Conclusion / References / Author Biography |
| frank starling law of the heart: Anatomy and Physiology J. Gordon Betts, Peter DeSaix, Jody E. Johnson, Oksana Korol, Dean H. Kruse, Brandon Poe, James A. Wise, Mark Womble, Kelly A. Young, 2013-04-25 |
| frank starling law of the heart: Physiology at a Glance Jeremy P. T. Ward, Roger W. A. Linden, 2017-03-07 Extensively revised and updated, this fourth edition of Physiology at a Glance continues to provide a thorough introduction to human physiology, covering a wealth of topics in a comprehensive yet succinct manner. This concise guide breaks this often complex subject down into its core components, dealing with structures of the body from the cellular level to composite systems. New to this edition are three chapters on cell signalling, thermoregulation, and altitude and aerospace physiology, as well as a glossary of terms to aid medical, dental, health science and biomedical students at all levels of their training. Featuring clear, full-colour illustrations, memorable data tables, and easy-to-read text, Physiology at a Glance is ideal as both a revision guide and as a resource to assist basic understanding of key concepts. |
| frank starling law of the heart: Data Interpretation in Anesthesia Tilak D. Raj, 2017-09-09 Focusing on the interpretation of data commonly available to anesthesiologists, this book presents a data point, followed by discussion in a question and answer format. Covering EKG's, X-Rays, MRI's, graphs, paper recordings, blood gas results, laboratory results, patient case histories and more, Data Interpretation in Anesthesia provides an enhanced and stimulating learning format for residents in training and practitioners alike. |
| frank starling law of the heart: Perioperative Hemodynamic Monitoring and Goal Directed Therapy Maxime Cannesson, Rupert Pearse, 2014-09-04 This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside. Successful hemodynamic monitoring and goal directed therapy require a wide range of skills. This book will enable readers to: • Detail the rationale for using perioperative hemodynamic monitoring systems and for applying goal directed therapy protocols at the bedside • Understand the physiological concepts underlying perioperative goal directed therapy for hemodynamic management • Evaluate hemodynamic monitoring systems in clinical practice • Learn about new techniques for achieving goal directed therapy • Apply goal directed therapy protocols in the perioperative environment (including emergency departments, operating rooms and intensive care units) • Demonstrate clinical utility of GDT and hemodynamic optimization using case presentations. Illustrated with diagrams and case examples, this is an important resource for anesthesiologists, emergency physicians, intensivists and pneumonologists as well as nurses and administrative officers. |
| frank starling law of the heart: Oxford Textbook of Advanced Critical Care Echocardiography Anthony McLean, Stephen Huang, Andrew Hilton, 2020 Provides a physiological and evidence-based reference guide to the principles and techniques of advanced echocardiography. Both transoesophageal and transthoracic echocardiography are addressed making this an ideal adjunct to more advanced echo courses for intensivists. |
| frank starling law of the heart: The Linacre lecture on the law of the heart Ernest Henry Starling, 1918 |
| frank starling law of the heart: Hemodynamic Monitoring Michael R. Pinsky, Jean-Louis Teboul, Jean-Louis Vincent, 2019-02-21 This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care. |
| frank starling law of the heart: Essential Anesthesia T. Y. Euliano, J. S. Gravenstein, N. Gravenstein, D. Gravenstein, 2011-06-02 Essential Anesthesia is a concise, accessible introduction to anesthetic practice. Now in its second edition, it provides a thorough overview of the science and practice of anesthesia. Part I describes the evaluation of the patient, the different approaches to anesthesia, and the post-operative care of the patient in pain. Part II introduces the essentials of physiology and pharmacology and their role in understanding the principles of anesthesia. The final part presents a step-by-step description of 14 clinical cases. These clinical vignettes give a very real introduction to the practicalities of anesthesia and will give the non-anesthetist physician an idea of how to prepare a patient for a surgical procedure. All chapters have been expanded and updated and an entirely new chapter on safety in healthcare has been added. This is the perfect introductory text for medical students, junior doctors and all operating theatre and critical care staff. |
| frank starling law of the heart: The Law of the Heart Boris Starling, 2021-08 Their love is against the laws of a merciless state--but the heart has its own power. For rollercoaster designer Theo, living on the edge is just part of the job. He's used to wandering the world perfecting thrills, his heart immune to commitment. But then a commission in repressive North Korea exposes him to emotions he's never dared to feel. Tour guide Min has a soul that wants to soar, but she knows it's safer to build walls around her heart and mind. Skilled in showcasing the mesmerising beauty of capital city Pyongyang without revealing its darker secrets, she introduces Theo to a country he will never forget--and begins to question her policy of quiet compliance. But forgetting--or pretending to--is the key to survival for Min's formidable grandmother Cuckoo. After a devastating heartbreak years ago, she learned that passion and oppression just don't mix. As Min and Theo grow closer and long-held secrets come to light, all three are forced to confront emotions they've tried to suppress. In a country where following their hearts will put them in danger, how much are they willing to risk? |
| frank starling law of the heart: Handbook of Cardiac Anatomy, Physiology, and Devices Paul A. Iaizzo, 2015-11-13 This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices. |
| frank starling law of the heart: Regulation of Coronary Blood Flow Michitoshi Inoue, Masatsugu Hori, Shoichi Imai, Robert M. Berne, 2013-11-09 Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow. |
| frank starling law of the heart: Oxford Textbook of Heart Failure Roy S. Gardner, Andrew L. Clark, Henry Dargie, 2011-07-14 Written by internationally renowned leaders in their field and relevant to all practicing clinicians, this textbook comprehensively covers all aspects of heart failure, and suggests the optimal evidence-based management for heart failure patients. |
| frank starling law of the heart: Biomechanics of Living Organs Yohan Payan, Jacques Ohayon, 2017-06-09 Biomechanics of Living Organs: Hyperelastic Constitutive Laws for Finite Element Modeling is the first book to cover finite element biomechanical modeling of each organ in the human body. This collection of chapters from the leaders in the field focuses on the constitutive laws for each organ. Each author introduces the state-of-the-art concerning constitutive laws and then illustrates the implementation of such laws with Finite Element Modeling of these organs. The focus of each chapter is on instruction, careful derivation and presentation of formulae, and methods. When modeling tissues, this book will help users determine modeling parameters and the variability for particular populations. Chapters highlight important experimental techniques needed to inform, motivate, and validate the choice of strain energy function or the constitutive model. Remodeling, growth, and damage are all covered, as is the relationship of constitutive relationships of organs to tissue and molecular scale properties (as net organ behavior depends fundamentally on its sub components). This book is intended for professionals, academics, and students in tissue and continuum biomechanics. Covers hyper elastic frameworks for large tissue deformations Considers which strain energy functions are the most appropriate to model the passive and active states of living tissue Evaluates the physical meaning of proposed energy functions |
| frank starling law of the heart: Applied Cardiovascular Physiology Michael Pinsky, 2012-12-06 A concise yet complete overview of the treatment of cardiovascular instability in the critically ill patient. The authors consider all aspects, ranging from basic physiology and pathophysiology to diagnostic tools and established and novel forms of therapy. The whole is rounded off with an integration of these principles into a series of clinically relevant scenarios. |
| frank starling law of the heart: Essentials of Cardiac Anesthesia for Noncardiac Surgery E-Book Joel A. Kaplan, 2018-07-21 Patients with cardiac conditions routinely present for noncardiac surgeries, requiring special protocols for perioperative assessment and management by the anesthesiologist. Essentials of Cardiac Anesthesia for Noncardiac Surgery: A Companion to Kaplan's Cardiac Anesthesia provides current, easily accessible information in this complex area, ideal for general anesthesiologists and non-cardiac subspecialists. From preoperative assessment through postoperative care, this practical reference covers all perioperative approaches to today's patients with cardiac conditions. - Provides guidance on the anesthetic diagnosis and management of the full range of cardiac lesions, helping minimize adverse outcomes and reduce complications for patients with common, complex, or uncommon cardiac conditions. - Includes complete coverage of echocardiography and current monitoring techniques needed for thorough perioperative assessment – all from the anesthesiologist's perspective. - Discusses safe and effective perioperative anesthetic management of patients presenting with advanced levels of cardiac care such as drug-eluting stents, multiple antiplatelet drugs, ventricular assist devices, multiple drugs for end-stage heart failure, and implanted electrical devices that produce cardiac resynchronization therapy, as well as patients with complicated obstetric problems or other significant cardiovascular issues. - Features a concise, easy-to-navigate format and Key Points boxes in each chapter that help you find answers quickly. |
| frank starling law of the heart: The Pressure Pulses in the Cardiovascular System Carl John Wiggers, 1928 Wiggers was a physiology professor at the Western Reserve University in Cleveland. He contributed to the knowledge of circulation and devised several instruments to promote the study on this subject. |
| frank starling law of the heart: Medical Physiology, 2e Updated Edition E-Book Walter F. Boron, Emile L. Boulpaep, 2012-01-13 Medical Physiology, in its updated 2nd edition, firmly relates molecular and cellular biology to the study of human physiology and disease. Drs. Walter Boron and Emile Boulpaep and a team of leading physiologists present you with practical, accurate coverage, continually emphasizing the clinical implications of the material. Each chapter explains the principles and organization of each body system, while more than 1400 high-quality, full-color line drawings and prominently featured clinical examples clarify every concept. This exceptionally detailed and comprehensive guide to physiology is ideal for a rich, straightforward, state-of-the-art understanding of this essential subject. Quickly review important content using prominent boxes included throughout the text to provide clinical examples of disordered physiology. Master difficult concepts with the use of 800 color drawings that feature balloon captions explaining key processes. Find information easily with the intuitive organization by body system and consistent style. Get up-to-date coverage of physiology with updated text and figures. Access the fully searchable text online at www.StudentConsult.com, along with Webnotes, Image Bank, 150 Self-assessment questions, and 10 physiology animations. Stay current thanks to updated material, including a new chapter on Physiology of Aging and a new section on hemostasis. Gain a clear visual understanding with a revised and updated art program of high-quality, full color line drawings and prominently featured clinical examples. |
| frank starling law of the heart: Clinical Fluid Therapy in the Perioperative Setting Robert G. Hahn, 2016-05-26 The world's most renowned researchers in fluid management explain what you should know when providing infusion fluids to surgical patients. |
| frank starling law of the heart: 1,000 Practice MTF MCQs for the Primary and Final FRCA Hozefa Ebrahim, Michael Clarke, Hussein Khambalia, 2019-01-10 A single, comprehensive text covering all the MCQs required to prepare for both the Primary and Final FRCA exams. |
| frank starling law of the heart: Linacre Lecture on the Law of the Heart Ernest Henry Starling, 1918 |
| frank starling law of the heart: Aortic Stenosis Masanori Hirota, 2011-10-10 Currently, aortic stenosis (AS) is the most prevalent valvular disease in developed countries. Pathological and molecular mechanisms of AS have been investigated in many aspects. And new therapeutic devices such as transcatheter aortic valve implantation have been developed as a less invasive treatment for high-risk patients. Due to advanced prevalent age of AS, further discovery and technology are required to treat elderly patients for longer life expectancy. This book is an effort to present an up-to-date account of existing knowledge, involving recent development in this field. Various opinion leaders described details of established knowledge or newly recognized advances associated with diagnosis, treatment and mechanism. Thus, this book will enable close intercommunication to another field and collaboration technology for new devices. We hope that it will be an important source, not only for clinicians, but also for general practitioners, contributing to development of better therapeutic adjuncts in the future. |
| frank starling law of the heart: Lippincott® Illustrated Reviews: Physiology Robin R. Preston, Thad E. Wilson, 2018-12-26 Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Enhanced by a new chapter, new illustrations, and new Q&As, LIppincott® Illustrated Reviews: Physiology, Second Edition brings physiology clearly into focus, telling the story of who we are; how we live; and, ultimately, how we die. By first identifying organ function and then showing how cells and tissues are designed to fulfill that function, this resource decodes physiology like no other text or review book. Tailored for ease of use and fast content absorption, the book’s outline format, visionary artwork, clinical applications, and unit review questions help students master the most essential concepts in physiology, making it perfect for classroom learning and test and boards preparation. |
| frank starling law of the heart: The Veterinary ICU Book Wayne E. Wingfield, Mark R. Raffe, 2020-06-03 This book is dedicated to the fundamental clinical signs of astute observation, careful differential diagnosis and analytical therapeutic decision-making in emergency veterinary settings. It clearly defines the physiological and clinical principles fundamental to the management of the critically ill small animal patient. With clear guidelines for organizing an emergency/critical care unit, the book also discusses ethical and legal concerns. The 80 expert authors have created a clinically specific resource for the specialist, residents in training, veterinary practitioners, technicians and students.Published by Teton New Media in the USA and distributed by CRC Press outside of North America. |
| frank starling law of the heart: Machina Carnis Dorothy M. Needham, 1971-11-30 This book is an account of the centuries of experiment and speculation that have led to our understanding of how muscles work. |
| frank starling law of the heart: Mechanisms of Heart Failure Pawan K. Singal, Ian M.C. Dixon, Robert E. Beamish, Naranjan S. Dhalla, 2012-12-06 Mechanisms of Heart Failure is based on papers selected from poster presentations made at the International Conference on Heart Failure, Winnipeg, May 20-23, 1994. Although the entire book is one continuous discussion of subcellular mechanisms of heart failure and its treatment, the presentation has been divided into three sections: the opening section on the subcellular basis of heart failure includes discussions of cytokines, signal transduction, metabolism, extracellular matrix, organ level changes and newer approaches to understanding the pathogenesis of heart failure. The second section focuses on the pathophysiological aspects of cardiomyopathies and their treatment. In the final section, medical, surgical and pharmacological approaches to the treatment of heart failure are discussed in clinical and animal laboratory settings. |
| frank starling law of the heart: Quantitative Human Physiology Joseph J Feher, 2017-01-02 Quantitative Human Physiology: An Introduction, winner of a 2018 Textbook Excellence Award (Texty), is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time, but requires a more analytical/quantitative approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles with an emphasis on quantitative aspects. - Winner of a 2018 Textbook Excellence Award (College) (Texty) from the Textbook and Academic Authors Association - Features a quantitative approach that includes physical and chemical principles - Provides a more integrated approach from first principles, integrating anatomy, molecular biology, biochemistry and physiology - Includes clinical applications relevant to the biomedical engineering student (TENS, cochlear implants, blood substitutes, etc.) - Integrates labs and problem sets to provide opportunities for practice and assessment throughout the course NEW FOR THE SECOND EDITION - Expansion of many sections to include relevant information - Addition of many new figures and re-drawing of other figures to update understanding and clarify difficult areas - Substantial updating of the text to reflect newer research results - Addition of several new appendices including statistics, nomenclature of transport carriers, and structural biology of important items such as the neuromuscular junction and calcium release unit - Addition of new problems within the problem sets - Addition of commentary to power point presentations |
| frank starling law of the heart: PanVascular Medicine Peter Lanzer, 2015-03-30 Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care. |
| frank starling law of the heart: Human Physiology Arthur J. Vander, James H. Sherman, Dorothy S. Luciano, 2001 This edition has been extensively updated with new genetics information, including such areas as the Human Genome Project, transcription factors and gene cloning. An increased number of summary tables help students review key concepts. |
| frank-starling law of the heart: Physics, Pharmacology and Physiology for Anaesthetists Matthew E. Cross, Emma V. E. Plunkett, 2014-03-06 A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams. |
| frank-starling law of the heart: Basic Physiology for Anaesthetists David Chambers, Christopher Huang, Gareth Matthews, 2019-07-25 Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource. |
| frank-starling law of the heart: Starling’s Law of The Heart Revisited Henk Keurs, M.I.M Noble, 2012-12-06 H. E. D. J. TER KEURS & M. I. M. NOBLE The Starling's Law of the Heart and The Frank-Starling Mechanism have long been the cornerstone of cardiac mechanical physiology. It is often forgotten that Frank and Starling carried out fundamentally different exper iments. Frankl measured the isovolumic pressure developed by frog heart at different volumes. He therefore discovered the pressure-volume-volume rela tionship which depends directly on the force-length relationship of the 2 sarcomeres. Starling ,3 studied cardiac shortening as manifest by cardiac output and its relationship to end-diastolic conditions as manifest by right atrial pressure. Thus he was studying the ability of cardiac muscle to shorten more at a given load from a greater initial length. Starling in the promulga 4 tions of his law implied a common mechanism for these two phenomena and spoke of the energy liberated being a function of initial muscle fiber length. However, there has been much confusion about the interrelationship between the two different aspects studied by Frank and Starling. The 1960s saw the era of isolated cardiac muscle mechanics, beginning with 5 the paper of Abbott and Mommaerts. Whole muscle length-tension relations were equated with sarcomere-length-tension relations by fixation of muscle at a particular point on the curve and determination of sarcomere length by electronmicroscopy. |
| frank-starling law of the heart: Cardiovascular Physiology Concepts Richard E. Klabunde, 2020-12-01 Praised for its concise coverage, this highly accessible monograph lays a foundation for understanding the underlying concepts of normal cardiovascular function and offers a welcome alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Clear explanations, ample illustrations and engaging clinical cases and problems provide the perfect guidance for self-directed learning and prepare you to excel in clinical practice. |
| frank-starling law of the heart: Oxford Dictionary of Sports Science and Medicine Michael Kent, 2006-12-01 The Oxford Dictionary of Sports Science and Medicine provides comprehensive and authoritative definitions of nearly 8000 sports science and sports medicine terms. All major areas are covered, including exercise psychology, sports nutrition, biomechanics, anatomy, sports sociology, training principles and techniques and sports injury and rehabilitation The dictionary will be an invaluable aid to students, coaches, athletes and anyone wanting instant access to the scientific principles, anatomical structures, and physiological, sociological and psychological processes that affect sporting performance. It will also be of interest to the general reader interested in sports science and medicine terminology. |
| frank-starling law of the heart: A Life of Ernest Starling John Henderson, 2013-11-18 Ernest Starling (1866-1927) was pre-eminent in the golden age of British Physiology. His name is usually associated with his Law of the Heart,” but his discovery of secretin (the first hormone whose mode of action was explained) and his work on capillaries were more important contributions. He coined the word 'hormone' one hundred years ago. His analysis of capillary function demonstrated that equal and opposite forces move across the capillary wall--an outward (hydrostatic) force and an inward (osmotic) force derived from plasma proteins. |
| frank-starling law of the heart: Anesthesiology Core Review Brian Freeman, Jeffrey Berger, 2014-07-06 A rigorous, high-yield review for the new ABA Part 1: BASIC Examination The year 2014 marks the beginning of a new phase in board certification for anesthesiology residents in the United States. The Part 1 exam is now split into two written examinations: Basic and Advanced. Anesthesiology. Residents who are unable to pass the Basic examination will not be allowed to finish their training. That's why this book is a true must read for every anesthesiology resident. It is the single best way to take the stress out of this make-or-break exam, focus your study on nearly 200 must-know topics found on the board exam outline, and identify your areas of strength and weakness. Written by program directors with many years of board examination advising experience, Anesthesiology Core Review Part One: BASIC Exam is designed to be the cornerstone of your study preparation. Each chapter of Anesthesiology Core Review succinctly summarizes key concepts in basic science and clinical anesthesia practice. Space is conveniently provided throughout the book to add notes from other study resources. Anesthesiology Core Review Part One: BASIC Exam is logical divided into four sections: Basic Science Clinical Sciences Organ-Based Sciences Special Issues in Anesthesiology (covering important topics such as professionalism and licensure, ethics, and patient safety) With its expert authorship and concise yet thorough coverage, Anesthesiology Core Review Part One: BASIC Exam is biggest step you can take to assure effective preparation for the new ABA BASIC Examination. |
| frank-starling law of the heart: Cardiovascular Hemodynamics for the Clinician George A. Stouffer, 2017-03-06 Cardiovascular Hemodynamics for the Clinician, 2nd Edition, provides a useful, succinct and understandable guide to the practical application of hemodynamics in clinical medicine for all trainees and clinicians in the field. Concise handbook to help both practicing and prospective clinicians better understand and interpret the hemodynamic data used to make specific diagnoses and monitor ongoing therapy Numerous pressure tracings throughout the book reinforce the text by demonstrating what will be seen in daily practice Topics include coronary artery disease; cardiomyopathies; valvular heart disease; arrhythmias; hemodynamic support devices and pericardial disease New chapters on TAVR, ventricular assist devices, and pulmonic valve disease, expanded coverage of pulmonary hypertension, fractional flow reserve, heart failure with preserved ejection fraction and valvular heart disease Provides a basic overview of circulatory physiology and cardiac function followed by detailed discussion of pathophysiological changes in various disease states |
| frank-starling law of the heart: Dilated Cardiomyopathy Gianfranco Sinagra, Marco Merlo, Bruno Pinamonti, 2019-05-17 This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease. |
| frank-starling law of the heart: Essential Clinical Anesthesia Review Linda S. Aglio, Robert W. Lekowski, Richard D. Urman, 2015-01-08 This concise, evidence-based board review book, organized according to the ABA keyword list, covers all the fundamental concepts needed to pass written and re-certification board examinations. Each chapter begins with a case scenario or clinical problem from everyday practice, followed by concise discussion and clinical review questions and answers. Discussion progresses logically from preoperative assessment and intraoperative management to postoperative pain management, enhancing the reader's knowledge and honing diagnostic and clinical management skills. New guidelines and recently developed standards of care are also covered. Serving as a companion to the popular textbook Essential Clinical Anesthesia, this resourceful work reflects the clinical experiences of anesthesia experts at Harvard Medical School as well as individually known national experts in the field of anesthesiology. This practical review is an invaluable resource for anesthesiologists in training and practice, whether studying for board exams or as part of continuing education and ABA recertification. |
| frank-starling law of the heart: Cardiovascular Physiology E-Book Achilles J. Pappano, Withrow Gil Wier, 2012-12-20 Cardiovascular Physiology gives you a solid understanding of how the cardiovascular system functions in both health and disease. Ideal for your systems-based curriculum, this title in the Mosby Physiology Monograph Series explains how the latest concepts apply to real-life clinical situations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Get clear, accurate, and up-to-the-minute coverage of the physiology of the cardiovascular system. Master the material easily with objectives at the start of each chapter; self-study questions, summaries, and key words and concepts. Grasp the latest concepts in vascular, molecular, and cellular biology as they apply to cardiovascular function, thanks to molecular commentaries in each chapter. Apply information to clinical situations with the aid of clinical commentaries and highlighted clinical vignettes throughout. |
| frank-starling law of the heart: Control of Cardiac Output David Young, 2010-01-01 Although cardiac output is measured as the flow of blood from the left ventricle into the aorta, the system that controls cardiac output includes many other components besides the heart itself. The heart’s rate of output cannot exceed the rate of venous return to it, and therefore, the factors governing venous return are primarily responsible for control of output from the heart. Venous return is affected by its pressure gradient and resistance to flow throughout the vascular system. The pressure gradient for venous return is a function of several factors including the blood volume flowing through the system, the unstressed vascular volume of the circulatory system, its capacitance, mean systemic pressure, and right atrial pressure. Resistance to venous return is the sum of total vascular resistance from the aortic valve to the right atrium. The sympathetic nervous system and vasoactive circulating hormones affect short-term resistance, whereas local tissue blood flow autoregulatory mechanisms are the dominant determinants of long-term resistance to venous return. The strength of contraction of the heart responds to changes in atrial pressure driven by changes in venous return, with small changes in atrial pressure eliciting large changes in strength of contraction, as described by the Frank–Starling mechanism. In addition, the autonomic nervous system input to the heart alters myocardial pumping ability in response to cardiovascular challenges. The function of the cardiovascular system is strongly affected by the operation of the renal sodium excretion–body fluid volume–arterial pressure negative feedback system that maintains arterial blood pressure at a controlled value over long periods. The intent of this volume is to integrate the basic knowledge of these cardiovascular system components into an understanding of cardiac output regulation. Table of Contents: Introduction / Venous Return / Cardiac Function / Integrated Analysis of Cardiac Output Control / Analysis of Cardiac Output Regulation by Computer Simulation / Analysis of Cardiac Output Control in Response to Challenges / Conclusion / References / Author Biography |
| frank-starling law of the heart: Anatomy and Physiology J. Gordon Betts, Peter DeSaix, Jody E. Johnson, Oksana Korol, Dean H. Kruse, Brandon Poe, James A. Wise, Mark Womble, Kelly A. Young, 2013-04-25 |
| frank-starling law of the heart: Physiology at a Glance Jeremy P. T. Ward, Roger W. A. Linden, 2017-03-07 Extensively revised and updated, this fourth edition of Physiology at a Glance continues to provide a thorough introduction to human physiology, covering a wealth of topics in a comprehensive yet succinct manner. This concise guide breaks this often complex subject down into its core components, dealing with structures of the body from the cellular level to composite systems. New to this edition are three chapters on cell signalling, thermoregulation, and altitude and aerospace physiology, as well as a glossary of terms to aid medical, dental, health science and biomedical students at all levels of their training. Featuring clear, full-colour illustrations, memorable data tables, and easy-to-read text, Physiology at a Glance is ideal as both a revision guide and as a resource to assist basic understanding of key concepts. |
| frank-starling law of the heart: Data Interpretation in Anesthesia Tilak D. Raj, 2017-09-09 Focusing on the interpretation of data commonly available to anesthesiologists, this book presents a data point, followed by discussion in a question and answer format. Covering EKG's, X-Rays, MRI's, graphs, paper recordings, blood gas results, laboratory results, patient case histories and more, Data Interpretation in Anesthesia provides an enhanced and stimulating learning format for residents in training and practitioners alike. |
| frank-starling law of the heart: Perioperative Hemodynamic Monitoring and Goal Directed Therapy Maxime Cannesson, Rupert Pearse, 2014-09-04 This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside. Successful hemodynamic monitoring and goal directed therapy require a wide range of skills. This book will enable readers to: • Detail the rationale for using perioperative hemodynamic monitoring systems and for applying goal directed therapy protocols at the bedside • Understand the physiological concepts underlying perioperative goal directed therapy for hemodynamic management • Evaluate hemodynamic monitoring systems in clinical practice • Learn about new techniques for achieving goal directed therapy • Apply goal directed therapy protocols in the perioperative environment (including emergency departments, operating rooms and intensive care units) • Demonstrate clinical utility of GDT and hemodynamic optimization using case presentations. Illustrated with diagrams and case examples, this is an important resource for anesthesiologists, emergency physicians, intensivists and pneumonologists as well as nurses and administrative officers. |
| frank-starling law of the heart: Oxford Textbook of Advanced Critical Care Echocardiography Anthony McLean, Stephen Huang, Andrew Hilton, 2020 Provides a physiological and evidence-based reference guide to the principles and techniques of advanced echocardiography. Both transoesophageal and transthoracic echocardiography are addressed making this an ideal adjunct to more advanced echo courses for intensivists. |
| frank-starling law of the heart: Oxford Textbook of Heart Failure Roy S. Gardner, Andrew L. Clark, Henry Dargie, 2011-07-14 Written by internationally renowned leaders in their field and relevant to all practicing clinicians, this textbook comprehensively covers all aspects of heart failure, and suggests the optimal evidence-based management for heart failure patients. |
| frank-starling law of the heart: The Linacre lecture on the law of the heart Ernest Henry Starling, 1918 |
| frank-starling law of the heart: Hemodynamic Monitoring Michael R. Pinsky, Jean-Louis Teboul, Jean-Louis Vincent, 2019-02-21 This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care. |
| frank-starling law of the heart: Handbook of Cardiac Anatomy, Physiology, and Devices Paul A. Iaizzo, 2015-11-13 This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices. |
| frank-starling law of the heart: Essential Anesthesia T. Y. Euliano, J. S. Gravenstein, N. Gravenstein, D. Gravenstein, 2011-06-02 Essential Anesthesia is a concise, accessible introduction to anesthetic practice. Now in its second edition, it provides a thorough overview of the science and practice of anesthesia. Part I describes the evaluation of the patient, the different approaches to anesthesia, and the post-operative care of the patient in pain. Part II introduces the essentials of physiology and pharmacology and their role in understanding the principles of anesthesia. The final part presents a step-by-step description of 14 clinical cases. These clinical vignettes give a very real introduction to the practicalities of anesthesia and will give the non-anesthetist physician an idea of how to prepare a patient for a surgical procedure. All chapters have been expanded and updated and an entirely new chapter on safety in healthcare has been added. This is the perfect introductory text for medical students, junior doctors and all operating theatre and critical care staff. |
| frank-starling law of the heart: The Law of the Heart Boris Starling, 2021-08 Their love is against the laws of a merciless state--but the heart has its own power. For rollercoaster designer Theo, living on the edge is just part of the job. He's used to wandering the world perfecting thrills, his heart immune to commitment. But then a commission in repressive North Korea exposes him to emotions he's never dared to feel. Tour guide Min has a soul that wants to soar, but she knows it's safer to build walls around her heart and mind. Skilled in showcasing the mesmerising beauty of capital city Pyongyang without revealing its darker secrets, she introduces Theo to a country he will never forget--and begins to question her policy of quiet compliance. But forgetting--or pretending to--is the key to survival for Min's formidable grandmother Cuckoo. After a devastating heartbreak years ago, she learned that passion and oppression just don't mix. As Min and Theo grow closer and long-held secrets come to light, all three are forced to confront emotions they've tried to suppress. In a country where following their hearts will put them in danger, how much are they willing to risk? |
| frank-starling law of the heart: 1,000 Practice MTF MCQs for the Primary and Final FRCA Hozefa Ebrahim, Michael Clarke, Hussein Khambalia, 2019-01-10 A single, comprehensive text covering all the MCQs required to prepare for both the Primary and Final FRCA exams. |
| frank-starling law of the heart: Regulation of Coronary Blood Flow Michitoshi Inoue, Masatsugu Hori, Shoichi Imai, Robert M. Berne, 2013-11-09 Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow. |
| frank-starling law of the heart: Applied Cardiovascular Physiology Michael Pinsky, 2012-12-06 A concise yet complete overview of the treatment of cardiovascular instability in the critically ill patient. The authors consider all aspects, ranging from basic physiology and pathophysiology to diagnostic tools and established and novel forms of therapy. The whole is rounded off with an integration of these principles into a series of clinically relevant scenarios. |
| frank-starling law of the heart: Biomechanics of Living Organs Yohan Payan, Jacques Ohayon, 2017-06-09 Biomechanics of Living Organs: Hyperelastic Constitutive Laws for Finite Element Modeling is the first book to cover finite element biomechanical modeling of each organ in the human body. This collection of chapters from the leaders in the field focuses on the constitutive laws for each organ. Each author introduces the state-of-the-art concerning constitutive laws and then illustrates the implementation of such laws with Finite Element Modeling of these organs. The focus of each chapter is on instruction, careful derivation and presentation of formulae, and methods. When modeling tissues, this book will help users determine modeling parameters and the variability for particular populations. Chapters highlight important experimental techniques needed to inform, motivate, and validate the choice of strain energy function or the constitutive model. Remodeling, growth, and damage are all covered, as is the relationship of constitutive relationships of organs to tissue and molecular scale properties (as net organ behavior depends fundamentally on its sub components). This book is intended for professionals, academics, and students in tissue and continuum biomechanics. Covers hyper elastic frameworks for large tissue deformations Considers which strain energy functions are the most appropriate to model the passive and active states of living tissue Evaluates the physical meaning of proposed energy functions |
| frank-starling law of the heart: Essentials of Cardiac Anesthesia for Noncardiac Surgery E-Book Joel A. Kaplan, 2018-07-21 Patients with cardiac conditions routinely present for noncardiac surgeries, requiring special protocols for perioperative assessment and management by the anesthesiologist. Essentials of Cardiac Anesthesia for Noncardiac Surgery: A Companion to Kaplan's Cardiac Anesthesia provides current, easily accessible information in this complex area, ideal for general anesthesiologists and non-cardiac subspecialists. From preoperative assessment through postoperative care, this practical reference covers all perioperative approaches to today's patients with cardiac conditions. - Provides guidance on the anesthetic diagnosis and management of the full range of cardiac lesions, helping minimize adverse outcomes and reduce complications for patients with common, complex, or uncommon cardiac conditions. - Includes complete coverage of echocardiography and current monitoring techniques needed for thorough perioperative assessment – all from the anesthesiologist's perspective. - Discusses safe and effective perioperative anesthetic management of patients presenting with advanced levels of cardiac care such as drug-eluting stents, multiple antiplatelet drugs, ventricular assist devices, multiple drugs for end-stage heart failure, and implanted electrical devices that produce cardiac resynchronization therapy, as well as patients with complicated obstetric problems or other significant cardiovascular issues. - Features a concise, easy-to-navigate format and Key Points boxes in each chapter that help you find answers quickly. |
| frank-starling law of the heart: Cardiovascular Physiology: Questions for Self Assessment Rodney J Levick, 2009-12-25 An Introduction to Cardiovascular Physiology provides the student with the key concepts of cardiovascular physiology, from the fundamentals of how the cardiovascular system works in both health and disease, through to a consideration of more complex physiological mechanisms. This brand new companion work Cardiovascular Physiology: Questions for Sel |
| frank-starling law of the heart: Clinical Fluid Therapy in the Perioperative Setting Robert G. Hahn, 2016-05-26 The world's most renowned researchers in fluid management explain what you should know when providing infusion fluids to surgical patients. |
| frank-starling law of the heart: The Pressure Pulses in the Cardiovascular System Carl John Wiggers, 1928 Wiggers was a physiology professor at the Western Reserve University in Cleveland. He contributed to the knowledge of circulation and devised several instruments to promote the study on this subject. |
| frank-starling law of the heart: Medical Physiology, 2e Updated Edition E-Book Walter F. Boron, Emile L. Boulpaep, 2012-01-13 Medical Physiology, in its updated 2nd edition, firmly relates molecular and cellular biology to the study of human physiology and disease. Drs. Walter Boron and Emile Boulpaep and a team of leading physiologists present you with practical, accurate coverage, continually emphasizing the clinical implications of the material. Each chapter explains the principles and organization of each body system, while more than 1400 high-quality, full-color line drawings and prominently featured clinical examples clarify every concept. This exceptionally detailed and comprehensive guide to physiology is ideal for a rich, straightforward, state-of-the-art understanding of this essential subject. Quickly review important content using prominent boxes included throughout the text to provide clinical examples of disordered physiology. Master difficult concepts with the use of 800 color drawings that feature balloon captions explaining key processes. Find information easily with the intuitive organization by body system and consistent style. Get up-to-date coverage of physiology with updated text and figures. Access the fully searchable text online at www.StudentConsult.com, along with Webnotes, Image Bank, 150 Self-assessment questions, and 10 physiology animations. Stay current thanks to updated material, including a new chapter on Physiology of Aging and a new section on hemostasis. Gain a clear visual understanding with a revised and updated art program of high-quality, full color line drawings and prominently featured clinical examples. |
| frank-starling law of the heart: Linacre Lecture on the Law of the Heart Ernest Henry Starling, 1918 |
| frank-starling law of the heart: Lippincott® Illustrated Reviews: Physiology Robin R. Preston, Thad E. Wilson, 2018-12-26 Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Enhanced by a new chapter, new illustrations, and new Q&As, LIppincott® Illustrated Reviews: Physiology, Second Edition brings physiology clearly into focus, telling the story of who we are; how we live; and, ultimately, how we die. By first identifying organ function and then showing how cells and tissues are designed to fulfill that function, this resource decodes physiology like no other text or review book. Tailored for ease of use and fast content absorption, the book’s outline format, visionary artwork, clinical applications, and unit review questions help students master the most essential concepts in physiology, making it perfect for classroom learning and test and boards preparation. |
| frank-starling law of the heart: Aortic Stenosis Masanori Hirota, 2011-10-10 Currently, aortic stenosis (AS) is the most prevalent valvular disease in developed countries. Pathological and molecular mechanisms of AS have been investigated in many aspects. And new therapeutic devices such as transcatheter aortic valve implantation have been developed as a less invasive treatment for high-risk patients. Due to advanced prevalent age of AS, further discovery and technology are required to treat elderly patients for longer life expectancy. This book is an effort to present an up-to-date account of existing knowledge, involving recent development in this field. Various opinion leaders described details of established knowledge or newly recognized advances associated with diagnosis, treatment and mechanism. Thus, this book will enable close intercommunication to another field and collaboration technology for new devices. We hope that it will be an important source, not only for clinicians, but also for general practitioners, contributing to development of better therapeutic adjuncts in the future. |
| frank-starling law of the heart: The Veterinary ICU Book Wayne E. Wingfield, Mark R. Raffe, 2020-06-03 This book is dedicated to the fundamental clinical signs of astute observation, careful differential diagnosis and analytical therapeutic decision-making in emergency veterinary settings. It clearly defines the physiological and clinical principles fundamental to the management of the critically ill small animal patient. With clear guidelines for organizing an emergency/critical care unit, the book also discusses ethical and legal concerns. The 80 expert authors have created a clinically specific resource for the specialist, residents in training, veterinary practitioners, technicians and students.Published by Teton New Media in the USA and distributed by CRC Press outside of North America. |
| frank-starling law of the heart: Machina Carnis Dorothy M. Needham, 1971-11-30 This book is an account of the centuries of experiment and speculation that have led to our understanding of how muscles work. |
| frank-starling law of the heart: Mechanisms of Heart Failure Pawan K. Singal, Ian M.C. Dixon, Robert E. Beamish, Naranjan S. Dhalla, 2012-12-06 Mechanisms of Heart Failure is based on papers selected from poster presentations made at the International Conference on Heart Failure, Winnipeg, May 20-23, 1994. Although the entire book is one continuous discussion of subcellular mechanisms of heart failure and its treatment, the presentation has been divided into three sections: the opening section on the subcellular basis of heart failure includes discussions of cytokines, signal transduction, metabolism, extracellular matrix, organ level changes and newer approaches to understanding the pathogenesis of heart failure. The second section focuses on the pathophysiological aspects of cardiomyopathies and their treatment. In the final section, medical, surgical and pharmacological approaches to the treatment of heart failure are discussed in clinical and animal laboratory settings. |
| frank-starling law of the heart: PanVascular Medicine Peter Lanzer, 2015-03-30 Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care. |
| frank-starling law of the heart: Physics of Heart and Circulation, Jan Strackee, N. Westerhof, 1993-09 This book is aimed at those working on the physical aspects of heart and circulation. However, the book has a much wider scope: it also presents the physical and mathematical basis for the study of biological systems, not only as a way of thinking but also presenting basic information on all aspects of the cardiovascular system, such as fluid dynamics, elasticity, potential theory, mathematical modelling, etc. The book is of interest to graduate students and researchers in biomedical engineering, medical physics and the clinical sciences. |
Frank–Starling law - Wikipedia
The Frank–Starling law of the heart (also known as Starling's law and the Frank–Starling mechanism) represents the relationship between stroke volume and end diastolic volume. [1] …
Frank-Starling Mechanism - CV Physiology
In honor of these two early pioneers, the ability of the heart to change its force of contraction and therefore stroke volume in response to changes in venous return is called the Frank-Starling …
Physiology, Frank Starling Law - StatPearls - NCBI Bookshelf
Jan 30, 2023 · The Frank-Starling mechanism plays a role in the compensation of systolic heart failure, buffering the fall in cardiac output to help preserve sufficient blood pressure to perfuse …
Frank-Starling Law of the Heart Explained - Bodytomy
The Frank-Starling law is an important part of our understanding of the human heart's physiology. In this article, we will learn about the various facets of the law, and how the heart deals with …
Frank-Starling Relationship | Circulation Research
Jan 11, 2002 · The Frank-Starling relationship is an intrinsic property of myocardium by which increased length (or ventricular volume) results in enhanced performance during the …
Frank-Starling relationship: Video, Causes, & Meaning - Osmosis
More than a century ago, two physiologists, Otto Frank and Ernest Starling discovered that as the heart gets filled up with more blood during diastole, it contracts harder and pumps out more …
The Frank-Starling mechanism | Deranged Physiology
Jun 14, 2020 · The Frank-Starling mechanism is an intrinsic cardiac autoregulatory mechanism. It ensures that stroke volume changes in proportion to the change in end-diastolic volume. The …
Frank–Starling law - Wikipedia
The Frank–Starling law of the heart (also known as Starling's law and the Frank–Starling mechanism) represents the relationship between stroke volume and end diastolic volume. [1] The law states …
Frank-Starling Mechanism - CV Physiology
In honor of these two early pioneers, the ability of the heart to change its force of contraction and therefore stroke volume in response to changes in venous return is called the Frank-Starling …
Physiology, Frank Starling Law - StatPearls - NCBI Bookshelf
Jan 30, 2023 · The Frank-Starling mechanism plays a role in the compensation of systolic heart failure, buffering the fall in cardiac output to help preserve sufficient blood pressure to perfuse …
Frank-Starling Law of the Heart Explained - Bodytomy
The Frank-Starling law is an important part of our understanding of the human heart's physiology. In this article, we will learn about the various facets of the law, and how the heart deals with …
Frank-Starling Relationship | Circulation Research
Jan 11, 2002 · The Frank-Starling relationship is an intrinsic property of myocardium by which increased length (or ventricular volume) results in enhanced performance during the subsequent …
Frank-Starling relationship: Video, Causes, & Meaning - Osmosis
More than a century ago, two physiologists, Otto Frank and Ernest Starling discovered that as the heart gets filled up with more blood during diastole, it contracts harder and pumps out more …
The Frank-Starling mechanism | Deranged Physiology
Jun 14, 2020 · The Frank-Starling mechanism is an intrinsic cardiac autoregulatory mechanism. It ensures that stroke volume changes in proportion to the change in end-diastolic volume. The …
