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| endometrial cancer adjuvant therapy: Management of Endometrial Cancer Mansoor R. Mirza, 2019-08-26 This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence. |
| endometrial cancer adjuvant therapy: Recent Advances in Endometrial Cancer Sumita Mehta, Bindiya Gupta, 2020-07-23 This book discusses in detail the recent advances in the management of endometrial cancer, including the latest therapies and diagnostic methods. The book focuses on treatment-oriented topics such as the role of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in endometrial cancer, and also explores treatment options in advanced disease stages, including hormonal therapy and targeted therapy. Providing insights into the evidence-based management guidelines for endometrial cancer, this book is a valuable resource for students, trainees and practitioners in the field of gynecology and gyne-oncology. |
| endometrial cancer adjuvant therapy: Clinical Gynecology Eric J. Bieber, Joseph S. Sanfilippo, Ira R. Horowitz, Mahmood I. Shafi, 2015-04-23 Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings. |
| endometrial cancer adjuvant therapy: Surgical Management of Advanced Pelvic Cancer Desmond C. Winter, Michael E. Kelly, 2021-11-01 An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide. |
| endometrial cancer adjuvant therapy: Adjuvant Therapy for Breast Cancer Monica Castiglione, Martine J. Piccart, 2009-07-11 Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable. |
| endometrial cancer adjuvant therapy: Berek and Hacker's Gynecologic Oncology Jonathan S. Berek, Neville F. Hacker, 2010 The focus of Berek and Hacker's for four editions has been on the application of basic and clinical science to the clinical practice of gynecologic oncology. That approach has been successful and the book has been well received. The Fifth Edition follows the format of the previous editions, with the addition of color. We will also include a fully searchable companion Website that includes an image bank. |
| endometrial cancer adjuvant therapy: Gynaecological Oncology for the MRCOG Mahmood Shafi, Helen Bolton, Ketankumar Gajjar, 2018-04-19 Extensive and up-to-date resource on the full range of gynaecological cancers; practically-focused and essential for the MRCOG examination. |
| endometrial cancer adjuvant therapy: Cancer and Aging M. Extermann, 2013-01-18 Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners. |
| endometrial cancer adjuvant therapy: Community Clinical Oncology Program (COOP) Alice Collins Hamm, 1985 |
| endometrial cancer adjuvant therapy: Molecular Genetics of Endometrial Carcinoma Lora Hedrick Ellenson, 2016-12-01 This comprehensive text provides a much-needed review of a disease that is currently garnering the interest of molecular biologists, translational scientists, and clinicians. The volume includes emerging developments in the molecular genetics of endometrial carcinoma. In addition to covering the basic genetics of endometrial carcinoma, chapters also cover a wide range of signaling pathways implicated in endometrial carcinoma. A section of the book includes a number of genetically engineered mouse models, which contribute to understanding the role of various genetic alterations in the development and progression of endometrial carcinoma. These models also provide preclinical models for developing effective targeted therapeutic approaches. Endometrial carcinoma is the most common malignancy of the female genital tract in the United States and the number of cases continues to increase around the world. This book is a meant to serve as a resource for a wide range of scientists, from molecular geneticists to signal transduction biologists, as well as to both clinicians and scientists interested in developing targeted therapeutic approaches for women with endometrial carcinoma. |
| endometrial cancer adjuvant therapy: Gynaecological Oncology Mahmood I. Shafi, Helena M. Earl, Li Tee Tan, 2009-12-03 Providing a thorough and up-to-date overview of the full range of gynaecological cancers, Gynaecological Oncology is a concise introduction, particularly useful for trainees working towards postgraduate examinations. The first section includes introductory chapters on epidemiology, screening and prevention, imaging, pathology, surgery, radiation therapy, chemotherapy, and palliation. The second part of the book covers the gynaecological cancer types in turn; each chapter following a similar format looking at clinical issues, staging, and principles of management. Where appropriate, flow-charts and diagrams are used to help the reader assimilate complex information. A chapter is devoted to decision-making, addressing those issues clinicians and women face when deciding on optimal management in given clinical scenarios. The book is practically based and is enhanced by highlighting learning points, management algorithms and clinical images. This is an invaluable resource for all doctors and allied health professionals dealing with women with gynaecological cancers. |
| endometrial cancer adjuvant therapy: Clinical Gynecologic Oncology E-Book Philip J. DiSaia, William T. Creasman, Robert S Mannel, D. Scott McMeekin, David G Mutch, 2017-02-04 The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers – a must-have reference for improving outcomes and providing effective care. A who’s who list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference. Contains useful appendices covering staging, screening, nutritional therapy, toxicity criteria, blood component therapy, and radiation therapy. Covers hot topics such as multi-panel genetic testing, target therapies, sentinel node concept in endometrial cancer and vulvar cancer, and robotic surgery. Updates include new quick-reference features such as key point boxes with bulleted lists, highlighted key text, enhanced chapter outlines, and a brand-new design throughout. Includes up-to-date references and algorithms, making this text a comprehensive resource for clinical practice, personal study, and exam review. Helps you take advantage of the latest advances in early detection and improved treatment options for gynecologic cancers, especially uterine and cervical cancers. |
| endometrial cancer adjuvant therapy: Gynecologic Cancer Patricia J. Eifel, David M. Gershenson, John J. Kavanagh, Elvio G. Silva, 2005-12-21 Gynecologic cancer includes cancer of the female lower genital tract: vagina, vulva, cervix, endometrium, uterus, and ovaries. Gynecologic Cancer is the fourth volume in the M.D. Anderson Cancer Care Series, featuring the current standard approach to gynecologic cancer care from the experts at M.D. Anderson Cancer Center. Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include primary prevention and early detection, preinvasive diseases of female lower genital tract, pathology and imaging of gynecologica malignancies, treatment of vaginal, cervical, endometrial, uterine cancers. Discussions also address fertility-sparing options for treatment of women with gynecologica cancers as well as sexuality in women with gyn malignancies. Each of the 20 chapters ends with an up-to-date list of suggested readings, as well as key practice points highlighting the most principles and practices of each chapter for at-a-glance reference. More than 80 illustrations complement the text. This thorough, practical volume is the essential clinical guide for the oncologists, surgeons, and all physicians involved in the care of patients with gynecologic cancer. |
| endometrial cancer adjuvant therapy: Radiation Therapy Techniques for Gynecological Cancers Kevin Albuquerque, Sushil Beriwal, Akila N. Viswanathan, Beth Erickson, 2019-02-19 This book is a practical guide to the use of modern radiation therapy techniques in women with gynecological cancers. Step-by-step instruction is provided on simulation, contouring, and treatment planning and delivery for cancers of the cervix, endometrium, vagina, and vulva. Beyond external beam radiation delivery, full details are presented on three-dimensional brachytherapy at all sites for which it is applicable. Moreover, in-depth guidance is offered on the various advanced techniques of radiation delivery, including intensity-modulated radiation therapy, image guidance for external beam and brachytherapy, and stereotactic body radiotherapy. Radiation therapy is a critical component of the multidisciplinary management of gynecological tumors. With modern technology, both external beam radiation and brachytherapy can be delivered in a highly conformal way. This requires precise contouring and accurate planning techniques. In clearly describing the indications for and the delivery of quality radiation therapy for gynecological tumors, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and radiotherapy residents. |
| endometrial cancer adjuvant therapy: Design and Analysis of Quality of Life Studies in Clinical Trials Diane L. Fairclough, 2010-01-07 Design Principles and Analysis Techniques for HRQoL Clinical TrialsSAS, R, and SPSS examples realistically show how to implement methods Focusing on longitudinal studies, Design and Analysis of Quality of Life Studies in Clinical Trials, Second Edition addresses design and analysis aspects in enough detail so that readers can apply statistical meth |
| endometrial cancer adjuvant therapy: Rectal Cancer Treatment M.W. Büchler, R. J. Heald, B. Ulrich, J. Weitz, 2005-10-11 Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer. |
| endometrial cancer adjuvant therapy: Pulmonary Metastasis Leonard Weiss, Harvey A. Gilbert, 1978 |
| endometrial cancer adjuvant therapy: Practical Radiation Oncology Supriya Mallick, Goura K. Rath, Rony Benson, 2019-11-25 This book addresses the most relevant aspects of radiation oncology in terms of technical integrity, dose parameters, machine and software specifications, as well as regulatory requirements. Radiation oncology is a unique field that combines physics and biology. As a result, it has not only a clinical aspect, but also a physics aspect and biology aspect, all three of which are inter-related and critical to optimal radiation treatment planning. In addition, radiation oncology involves a host of machines/software. One needs to have a firm command of these machines and their specifications to deliver comprehensive treatment. However, this information is not readily available, which poses serious challenges for students learning the planning aspect of radiation therapy. In response, this book compiles these relevant aspects in a single source. Radiation oncology is a dynamic field, and is continuously evolving. However, tracking down the latest findings is both difficult and time-consuming. Consequently, the book also comprehensively covers the most important trials. Offering an essential ready reference work, it represents a value asset for all radiation oncology practitioners, trainees and students. |
| endometrial cancer adjuvant therapy: Principles and Practice of Gynecologic Oncology William J. Hoskins, Carlos A. Perez, Robert Crabill Young, 2000 he thoroughly updated Third Edition of this acclaimed reference incorporates the latest advances in the multidisciplinary therapy of gynecologic cancer. The book provides comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies. Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist. New chapters in this edition cover laparoscopic surgery and national strategies for gynecologic cancer. More than 30 percent of the chapters have been completely rewritten. This edition also includes new full-color illustrations |
| endometrial cancer adjuvant therapy: Carbon-Ion Radiotherapy Hirohiko Tsujii, Tadashi Kamada, Toshiyuki Shirai, Koji Noda, Hiroshi Tsuji, Kumiko Karasawa, 2013-12-25 This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy. |
| endometrial cancer adjuvant therapy: Principles and Practice of Gynecologic Oncology Richard R. Barakat, Maurie Markman, Marcus Randall, 2009 Providing comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies, this edition has 30 percent new contributing authors and new material. A companion Web site offers a fully searchable text. |
| endometrial cancer adjuvant therapy: Image-Guided Cancer Therapy Damian E. Dupuy, Yuman Fong, William N. McMullen, 2013-08-06 Image-Guided Cancer Therapy: A Multidisciplinary Approach provides clinicians with in-depth coverage of the growing, dynamic field of interventional oncology. Combining the knowledge of expert editors and authors into one powerhouse reference, this book looks at tumor ablation, HIFU, embolic therapies, emerging technologies, and radiation therapy throughout the body (liver, bone, breast, gynecologic and prostate cancers, to name just a few) , and includes discussion of different imaging modalities. In the words of Peter Mueller, MD, author of the book’s Foreword: “... The senior authors are all world renowned experts in interventional oncology, which is another example of the high quality authorship and experience that is brought to this book. The later chapters discuss therapies that are simply not covered in any other source. Everyone who is doing or wants to do ablation therapies and interventional oncology will face a time when they will be asked to use their expertise in less used and less investigated areas. There is nowhere else where the reader can get information on the prostate, breast, and gynecologic areas, and especially pediatrics....This book is an outstanding contribution to the literature and will become a ‘must read’ for all physicians who are interested in Interventional Oncology.” |
| endometrial cancer adjuvant therapy: Gynecologic Radiation Oncology: A Practical Guide Patricia Eifel, Ann H. Klopp, 2016-07-13 Offering practical approaches to common clinical problems, Gynecologic Radiation Oncology: A Practical Guide compiles the extensive clinical experience of Drs. Patricia J. Eifel and Ann H. Klopp from MD Anderson Cancer Center into one user-friendly volume. This reference addresses practical aspects of the field: how to evaluate the role of radiation therapy in various clinical settings, how to explain the rationale for treatment recommendations to referring physicians and patients, when and how to apply various external beam and brachytherapy techniques to address specific clinical problems, and how to monitor and manage patients during and after treatment. The book focuses on the following items, which can have immediate application to the treatment of patients with gynecologic cancers. |
| endometrial cancer adjuvant therapy: Accelerated Partial Breast Irradiation David E. Wazer, Douglas W. Arthur, Frank Vicini, 2009-08-11 Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text is a concise handbook designed to assist the clinician in the implementation of APBI. This includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications. |
| endometrial cancer adjuvant therapy: Mini Nutritional Assessment (MNA) Bruno J. Vellas, Philip J. Garry, Yves Guigoz, Nestlé Nutrition Services, 1999 This book is the first of a new series which will present the proceedings of the newly established Nestlé Nutrition Workshop Series: Clinical & Performance Programme aimed at adult nutrition. Undernutrition is a common phenomenon in elderly people, and malnutrition reaches significant levels in those being in hospital, nursing homes or home care programs. Consequences of malnutrition often go unrecognised owing to the lack of specific validated instruments to assess nutritional status in frail elderly persons. The Mini Nutritional Assessment (MNA) provides a single, rapid assessment of nutritional status in the elderly of different degrees of independence, allowing the prevalence of protein-energy malnutrition to be determined and to evaluate the efficacy of nutritional intervention and strategies. Easy, quick and economical to perform, it enables staff to check the nutritional status of elderly people when they enter hospitals or institutions and to monitor changes occurring during their stay. Moreover, the MNA is predictive of the cost of care and length of stay in hospital. This publication will be of immense assistance to heads of geriatric teaching units, teachers in nutrition, clinicians general practitioners and dieticians, enabling them to better detect, recognise and start treatment of malnutrition in the elderly. |
| endometrial cancer adjuvant therapy: Brachytherapy Paolo Montemaggi, Mark Trombetta, Luther W. Brady, 2016-04-21 This volume is the first truly international text to take the practitioner from the history, the physical basis, and the rationale of brachytherapy through to the techniques, the results, and the management of complications. It is also the first truly comprehensive and complete textbook of brachytherapy. The chapters on the physics of brachytherapy and the technical planning of internal and surface radiotherapy are designed to enhance the practitioner’s knowledge base and capabilities in this demanding specialty field. Disease site-specific chapters cover a wide range of applications, including ocular tumors, soft tissue sarcomas, cancers of the head and neck, skin, breast, lung, esophagus, and prostate, and gynecologic and anorectal malignancies. Each chapter incorporates the American and European guidelines and the text has been written from both perspectives by many of the most noted global experts in the field. A concluding chapter is devoted to brachytherapy quality assurance. |
| endometrial cancer adjuvant therapy: The Uterus Henry J. Norris, Arthur Tremain Hertig, Murray R. Abell, 1973 |
| endometrial cancer adjuvant therapy: Gynecologic Cancer David Marc Gershenson, 2004 This brand-new reference provides multidisciplinary guidance on the biology, diagnosis, treatment, and supportive care of patients with cancers of the female reproductive tract. An international group of experts present sections on management controversies, complications of cancer treatment, surgical techniques, symptom management, and more. |
| endometrial cancer adjuvant therapy: Female Genital Tumours: Who Classification of Tumours W. H. O. Classification WHO Classification of Tumours Editorial Board, Who Classification of Tumours Editorial, 2020-09-30 ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Female Genital Tumours is the fourth volume in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. What's new in this edition? The 5th edition, guided by the WHO Classification of Tumours Editorial Board, will establish a single coherent cancer classification presented across a collection of individual volumes organized on the basis of anatomical site (digestive system, breast, soft tissue and bone, etc.) and structured in a systematic manner, with each tumour type listed within a taxonomic classification: site, category, family (class), type, and subtype. In each volume, the entities are now listed from benign to malignant and are described under an updated set of headings, including histopathology, diagnostic molecular pathology, staging, and easy-to-read essential and desirable diagnostic criteria. Who should read this book? - Pathologists - Oncologists - Cancer researchers - Surgeons - Epidemiologists - Cancer registrars This volume - Prepared by 191 authors and editors - Contributors from around the world - More than 850 high-quality images - More than 3100 references |
| endometrial cancer adjuvant therapy: Long-term Tamoxifen Treatment for Breast Cancer Virgil Craig Jordan, 1994 During the past twenty years tamoxifen has become the most widely prescribed and most successful drug used in the treatment of breast cancer. In this volume, editor V. Craig Jordan provides articles that trace the development, pharmacology, and clinical research surrounding this drug which, by the year 2000, could be used to treat as many as one million women annually. Drawing from research conducted by specialists in the United States, the United Kingdom, and Italy, the series of articles describes the clinical testing of tamoxifen, highlighting the benefits. Studies show that tamoxifen lowers cholesterol and can potentially protect women against osteoporosis and fatal coronary heart disease. Equally important is a discussion of side effects and possible drug interactions and how these issues relate to patient concerns. An investigation of the development of a new class of drugs for use after tamoxifen fails provides valuable insight into future treatments, as the contributers consider possible resistance to tamoxifen. This volume provides invaluable information for physicians and surgeons who care for patients with breast cancer and for women interested in exploring this therapeutic dimension. |
| endometrial cancer adjuvant therapy: Breast Cancer Kelly K. Hunt, Geoffrey L. Robb, Eric A. Strom, Naoto T. Ueno, 2013-06-05 I am honored to write the Foreword for this first volume of the M. D. Anderson Cancer Care series, because I believe the book represents a milestone not only for M. D. Anderson but also for cancer specialists everywhere. All of us, whether we work in academic medical institu tions, medical school hospitals, community hospitals, oncology clinics, or solo practice, have seen remarkable changes in our practice over the recent decades. We know that breast cancer patients live longer, feel better, and look better than ever before, and they face this dreaded disease with more optimism than ever before. Each of us deserves to be proud of this progress. Though I am now primarily a laboratory scientist and admin istrator, I am proud of my own work on factors that control the growth of tumor cells, most prominently through regulation of EGF receptors and HER-2/neu, and the promise that work holds for women who have breast cancer. The authors represented in this volume have made important contri butions to breast cancer care. Likewise, every reader of this book has and will continue to make critical contributions to the health of women with breast cancer. I would like to express the hope here that each of us takes the opportunity to step outside our subspecialties-surgeon, internist, radiation oncologist, pathologist, radiologist, laboratory scientist-and learn how we can better integrate our work with that of other specialists. |
| endometrial cancer adjuvant therapy: Management of Early Stage Breast Cancer Beena Kunheri, D. K. Vijaykumar, 2020-10-01 Breast cancer, its causes, early detection and treatment have received considerable attention, since this widespread disease is one of the most important health concerns for women. This book provides a comprehensive overview of the diagnostic and therapeutic aspects of the management of early-stage breast cancer, including essential information on basic topics like pathology, and radiology, as well as the latest developments. Further, it discusses all aspects of surgical care, chemotherapy and radiation therapy, together with the controversies and current management guidelines. Helping readers acquire a deep, holistic understanding of the topic, the book is a valuable resource for practitioners and postgraduate students in the field of gynecologic oncology. Moreover, it is a useful aid to decision-making in day-to-day practice for oncologists, residents, fellows and experienced practitioners. |
| endometrial cancer adjuvant therapy: Adjuvant Therapy of Breast Cancer I. Craig Henderson, 2012-11-05 The results of randomized trials evaluating the use of early or adjuvant systemic treatment for patients with resectable breast cancer provide an eloquent rebuttal to those who would argue that we have made no progress in the treatment of cancer. Many of the tumors that we have been most successful in curing with chemotherapy and other newer forms of treatment are relatively uncommon. In contrast, breast cancer continues to be the single most common malignancy among women in the western world, is increasingly a cause of death throughout Asia and Third-World countries, and remains one of the most substantial causes of cancer mortality world wide. The use of mammography as a means of early detection has been shown to reduce breast cancer mortality by 25-35% among those popu lations in which it is utilized. The use of adjuvant systemic treatment in appropriate patients provides a similar (and additional) reduction in breast cancer mortality. Few subjects have been so systematically studied in the history of medicine, and it seems fair to conclude that the value to adjuvant systemic therapy in prolonging the lives of women with breast cancer is more firmly supported by empirical evidence than even the more conventional or primary treatments using various combinations ofsurgery and radiotherapy. |
| endometrial cancer adjuvant therapy: Cancer of the Female Reproductive Organs National Cancer Institute (U.S.), 1959 |
| endometrial cancer adjuvant therapy: Surgery for Ovarian Cancer Robert E. Bristow, Beth Y. Karlan, Dennis S. Chi, 2019-02-21 Updated and expanded, the third edition of Surgery for Ovarian Cancer focuses on essential techniques for the effective management of ovarian cancer. It reflects the most contemporary science and surgical applications for the management of patients with ovarian cancer and related peritoneal surface malignancies. This new edition takes a step-by-step approach and includes new intraoperative photographs and videos illustrating surgical procedures. It is principally devoted to the technical aspects of cytoreductive surgery, with chapters divided according to anatomic region. The chapters cover relevant anatomical considerations, surgical challenges specific to each region, and operative approaches and techniques favored by the authors. The list of contributing authors has been expanded from the previous edition and includes international and world-renowned experts from the fields of gynecologic oncology and surgical oncology. The topics of minimally invasive surgery, secondary cytoreduction, palliative surgery, and postoperative care are also covered in detail. New to the third edition are chapters on preoperative risk stratification, regional therapeutics and peritonectomy procedures, and quality assurance relating to ovarian cancer surgery. This comprehensive text is essential reading for all practitioners working with patients with ovarian cancers. |
| endometrial cancer adjuvant therapy: Artificial Immune Systems: A New Computational Intelligence Approach Leandro Nunes de Castro, Jonathan Timmis, 2002-09-23 Artificial Immune Systems (AIS) are adaptive systems inspired by the biological immune system and applied to problem solving. This book provides an accessible introduction that will be suitable for anyone who is beginning to study or work in this area. It gives a clear definition of an AIS, sets out the foundations of the topic (including basic algorithms), and analyses how the immune system relates to other biological systems and processes. No prior knowledge of immunology is needed - all the essential background information is covered in the introductory chapters. Key features of the book include: - A discussion of AIS in the context of Computational Intelligence; - Case studies in Autonomous Navigation, Computer Network Security, Job-Shop Scheduling and Data Analysis =B7 An extensive survey of applications; - A framework to help the reader design and understand AIS; - A web site with additional resources including pseudocodes for immune algorithms, and links to related sites. Written primarily for final year undergraduate and postgraduate students studying Artificial Intelligence, Evolutionary and Biologically Inspired Computing, this book will also be of interest to industrial and academic researchers working in related areas. |
| endometrial cancer adjuvant therapy: Diagnostic Gynecologic and Obstetric Pathology E-Book Christopher P. Crum, Kenneth R. Lee, Marisa R. Nucci, Scott R. Granter, Brooke E. Howitt, Mana M. Parast, Theonia Boyd, William A Peters III, 2017-10-13 Comprehensive and practice-oriented, the fully updated 3rd Edition of this easy-to-use text covers the full range of obstetric and gynecologic pathology, including information on treatment and patient management. Written largely by the pathology and clinical faculty at Harvard's Brigham and Women's Hospital, it covers the most up-to-date information available in the field, including molecular genetics and diagnostics. Drs. Christopher P. Crum and Marisa R. Nucci are joined by new editors Scott R. Granter, Brooke E. Howitt, Mana M. Parast, and Theonia K. Boyd, to provide complete, beautifully illustrated coverage of both neoplastic and non-neoplastic disorders of the female genital system, ideal for improving pathological diagnosis. - Provides distinct diagnostic/differential diagnostic criteria for any potential obstetric/gynecologic specimen encountered in practice. - Features more than 2,250 full-color images, key points at the end of each chapter, and an appendix with commonly used ICD-10 codes - Covers topics not often found in gynecologic pathology textbooks, such as vulvodynia, and diseases of the anus. - Approaches topics from a practice-oriented point of view, beginning with clinical presentation and progressing through histopathology, differential diagnosis, and treatment for each disorder. - Emphasizes new practice issues and their biologic basis including approaches to vulvar, cervical and endometrial precursors as well as the underpinnings of cervical, endometrial and ovarian cancer. - A comprehensive look at mesenchymal neoplasia, including not only lower genital tract and uterus but also the retroperitoneum. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. |
| endometrial cancer adjuvant therapy: Diagnosing and Treating Adult Cancers and Associated Impairments National Academies Of Sciences Engineeri, National Academies of Sciences Engineering and Medicine, Health And Medicine Division, Board On Health Care Services, Committee on Diagnosing and Treating Adult Cancers, 2021-11-10 Cancer is the second leading cause of death among adults in the United States after heart disease. However, improvements in cancer treatment and earlier detection are leading to growing numbers of cancer survivors. As the number of cancer survivors grows, there is increased interest in how cancer and its treatments may affect a person's ability to work, whether the person has maintained employment throughout the treatment or is returning to work at a previous, current, or new place of employment. Cancer-related impairments and resulting functional limitations may or may not lead to disability as defined by the U.S. Social Security Administration (SSA), however, adults surviving cancer who are unable to work because of cancer-related impairments and functional limitations may apply for disability benefits from SSA. At the request of SSA, Diagnosing and Treating Adult Cancers and Associated Impairments provides background information on breast cancer, lung cancer, and selected other cancers to assist SSA in its review of the listing of impairments for disability assessments. This report addresses several specific topics, including determining the latest standards of care as well as new technologies for understanding disease processes, treatment modalities, and the effect of cancer on a person's health and functioning, in order to inform SSA's evaluation of disability claims for adults with cancer. |
| endometrial cancer adjuvant therapy: Hyperthermia in Cancer Therapy F. Kristian Storm, 1983 |
| endometrial cancer adjuvant therapy: Current Concepts in Endometrial Cancer Ranu Patni, 2018-08-07 This book comprehensively covers endometrial carcinoma, a type of gynecological cancer that is often overlooked but of great interest. Although the incidence of the disease is rapidly increasing, both per se and as part of familial cancer syndromes, there is a great deal of controversy regarding its diagnosis, evaluation and management. This book underlines the significance of endometrial carcinoma, highlights key prevention measures, charts its evaluation, and addresses the stage-by-stage management of this malignancy, with particular attention to the role of minimally invasive surgery. Further, it includes a chapter on future perspectives including robotics, targeted therapies and other developments in the offing. divOverall, the book provides a comprehensive guide to endometrial cancer, which if approached properly, can have an excellent prognosis, thus saving many lives and/or achieving substantially improved quality of life.> |
Endometrial cancer - Symptoms and causes - Mayo Clinic
Jan 10, 2025 · Endometrial cancer is a type of cancer that begins as a growth of cells in the uterus. The uterus is the hollow, pear-shaped pelvic organ where fetal development happens. …
What Is Endometrial Cancer? | American Cancer Society
Endometrial cancer (also called endometrial carcinoma) starts in the cells of the inner lining of the uterus (the endometrium). This is the most common type of uterine cancer. Endometrial …
Endometrial Cancer - Johns Hopkins Medicine
Endometrial cancer is the most common cancer in the uterus. Recognizing the symptoms of endometrial cancer can lead to early detection and more treatment options.
Endometrial cancer - Wikipedia
Endometrial cancer is a cancer that arises from the endometrium (the lining of the uterus or womb). [1] It is the result of the abnormal growth of cells that can invade or spread to other parts of the …
Endometrial (Uterine) Cancer: Symptoms, Causes, and More
May 12, 2025 · Endometrial cancer is a type of uterine cancer that starts in the inner lining of the uterus. This lining is called the endometrium. According to the National Cancer Institute (NCI),...
Uterine (Endometrial) Cancer Symptoms, Staging, Treatment ...
Uterine (endometrial) cancer is the fourth most common cancer in women in the U.S. Abnormal vaginal bleeding is the most common sign of uterine cancer. Discover what causes uterine …
Uterine Cancer (Endometrial Cancer): Symptoms & Treatment
There are two types of uterine cancer: endometrial and uterine sarcoma. Treatment for uterine cancer may consist of a hysterectomy. Learn the symptoms and treatment options for uterine …
WebMD Uterine Cancer (Endometrial) Resource Center
Understanding Endometrial Cancer. Learn about the symptoms, risk factors, and treatment options for endometrial cancer. Early detection can improve outcomes.
What is Endometrial Cancer? Symptoms, Risk Factors ...
Endometrial cancer is the most common cancer of the female reproductive organs. It starts in the endometrium, a layer of tissue that lines the interior of the uterus, or womb. The uterus is where …
What you should know about endometrial cancer | Ohio State ...
Apr 17, 2024 · Endometrial cancer occurs when cells of the endometrium, or the inner lining of the uterus, change and start to grow out of control. It’s the most frequently diagnosed cancer in the …
Hormonal therapy or chemotherapy for early-stage, low …
Feb 25, 2022 · Endometrial cancer Malignant peritoneal cytology Early stage Low grade Adjuvant therapy Hormone therapy Chemotherapy 1. Introduction In the United States, endometrial …
Pembrolizumab plus Chemotherapy in Advanced …
Mar 27, 2023 · Previous adjuvant chemotherapy was permitted if the treatment-free interval was at least 12 months. The primary outcome was ... Cancer Therapy–Endometrial [FACT-En …
NRG Oncology/RTOG Consensus Guidelines for Delineation of …
Endometrial cancer and early stage cervical cancer are treated with surgery with or without adjuvant radiation therapy or chemotherapy.1-7 For endometrial cancer, adju-vant radiation …
Early Stage Endometrial Cancer - American Society for …
High-Intermediate Risk are stage I endometrial cancer patients who require adjuvant treatment Common risk factors include: • GOG99 HIR: age ≥70 with 1 risk factor, ≥50 with 2 risk factors, …
Histology-specific prognostic significance of isolated tumor …
Feb 17, 2025 · • Tumor metastatic size was more prognostic than anatomical location in node-metastasized endometrial cancer. • Isolated tumor cells were prognostic in low-grade …
LVSI positive and NX in early endometrial cancer: Surgical …
Invited review LVSI positive and NX in early endometrial cancer: Surgical restaging (and no further treatment if N0), or adjuvant ERT? Katherine L. Harris a, b, *, Kathryn A. Maurer a, b, …
Treatment of Endometrial Cancer - advances-oncology.com
Examination of recent randomized trials in high-risk endometrial cancer and impact on adjuvant radiotherapy and systemic therapy recommendations. Overview of recent trials evaluating role …
Synchronous primary cancers of the endometrium and ovary
1) or ovarian cancer (n ¼ 5) and stage I/II endometrial or ovarian cancer in the group of early stage (n ¼ 21). The mean survival in the group of early stage was 68 months, and 15 months …
Looking beyond carboplatin and paclitaxel for the treatment …
of advanced/recurrent endometrial cancer ... ation Therapy in EndometrialCarcinoma(PORTEC) 3 trial, in whichthe greatest benefit with the addition of adjuvant chemotherapy was seen in …
Dostarlimab for Primary Advanced or Recurrent Endometrial …
Mar 27, 2023 · [FIGO] stage III or IV) endometrial cancer that was not amenable to curative therapy. Patients ... adjuvant or adjuvant systemic therapy and had recurred or progressed at …
High-risk Endometrial Cancer: The Present and Future of …
Surgery remains the primary treatment modality for women with resectable endometrial cancer. However, the optimal adjuvant therapy following surgical resection and staging remains an …
Orta-yüksek Risk ve Yüksek Risk Endometrium Kanserinde …
Keywords: Endometrial cancer, adjuvant therapy, radiotherapy, high-intermediate risk, high risk Atıf: Erdoğan M, Güzelöz Z, Demir G, Ebruli C, Eyiler F, Keser M, Ünal OÜ, Emiroğlu M. …
Endometrial Cancer Pocket Guidelines - European Society …
indicated in the surgical management of endometrial cancer? 6. How radical should the surgery be in different stafes and pathological subtypes of endometrial cancer? 7. What is the current …
INDICATIONS FOR ADJUVANT RADIOTHERAPY IN …
with low-risk endometrial cancer and 10% in patients with high-risk endometrial cancer, had they been given adjuvant radiotherapy. If, of 100 patients, 70 are diagnosed with low-risk …
Adjuvant combined-modality therapy for stage IIIC …
Adjuvant therapy 1. Introduction Endometrial cancer is the most common gynecologic malignancy in high-resource countries, with over 63,000 new cases per year in the United …
Molecular subtype stratified outcomes according to adjuvant …
Molecular subtype stratified outcomes according to adjuvant therapy in endometrial cancer Amy Jamiesona, Jutta Huvilab, Samuel Leungc, ... ESMO high, advanced, metastatic risk groups …
The role of postoperative radiation therapy for endometrial …
stage endometrial cancer who do not receive adjuvant radiation therapy is the vaginal cuff.3 Vaginal cuff brachytherapy reduces the risk of recurrence in the vagina and causes …
Japanese Gynecologic Oncology Group Endometrial …
as adjuvant chemotherapy for endometrial cancer at a high risk of recurrence Lead principal investigator: Daisuke Aoki, Department of Obstetrics & ... including the establishment of …
HIGHLIGHTS OF PRESCRIBING INFORMATION for 4 cycles, …
or recurrent endometrial cancer that is mismatch repair deficient (dMMR) as determined by an FDA- approved test. (1.5, 2.1) • in combination with gemcitabine and cisplatin as neoadjuvant …
Chemo- and Radiotherapy in Adjuvant Management of …
stage endometrial cancer who underwent adjuvant therapy, 171 (48%) received RT alone, 102 (29%) underwent chemotherapy alone, and 83 (23%) un-derwent combined chemo-RT. …
Endometrial Cancer: Highlight Reel - Gynecologic Oncology …
Nov 2, 2021 · TPC in patients with previously treated, advanced endometrial cancer, including in patients with pMMR status and all-comers and regardless of – Histology, including difficult -to …
A Case Report of Endometrial Cancer Metastatic to the …
metastatic endometrial cancer to the bowel in a patient with a history of endometrial cancer. Patients rarely refuse any kind of cancer therapy allowing observation of the natural course of …
Adjuvant Chemotherapy plus Radiation for Locally Advanced …
n engl j med 380;24 nejm.orgJune 13, 2019 2319 Chemotherapy plus Radiation for Endometrial Cancer all survival, the incidence and severity of acute and late toxic effects, and …
CCTG EN10: A phase II study of tailored adjuvant therapy in …
CCTG EN10: A phase II study of tailored adjuvant therapy in POLE-mutated and p53-wildtype/NSMP early-stage endometrial cancer (EC)—RAINBO BLUE and TAPER. Jessica N. …
#411 The role of vaginal brachytherapy in the treatment of …
noma and those receiving adjuvant therapy to evaluate the efficacy of brachytherapy compared to standard external beam radiation therapy. Methodology A total of 116 patients who underwent …
Clinical Management Guideline for Endometrial Cancer West …
Endometrial Cancer: Post Surgical Risk Stratification & Adjuvant Therapy* Version 3.1 Final (20171020) Page 4 of 7 * Reference: ESMO-ESGO-ESTRO Consensus Conference on …
Endometrial Carcinoma: Survival Analysis at a Tertiary Care
Introduction Endometrial cancer is the fourth common gynecological cancer in India. It is predominantly a disease of postmenopausal women. The predicted rise of endometrial cancer …
ESMO-ESGO-ESTRO Consensus Conference on Endometrial …
adjuvant therapy? 8. What are the best evidence-based adjuvant treatment strategies for patients with low- and intermediate-risk endometrial cancer? 9. What are the best evidence-based …
Biomarker-driven therapy in endometrial cancer
selected adjuvant therapy trial in endometrial cancer, is evaluating the addition of pembrolizumab to radiation in newly diagnosed early-stage dMMR endometrioid endometrial cancer and has …
Lymph node micrometastases and outcome of endometrial …
• We investigated the survival impact of lymph node micrometastases in endometrial cancer. • Lymph node micrometastases are associated with adverse outcome in endometrial cancer. • …
American Brachytherapy Society recurrent carcinoma of the …
intraoperative radiation therapy, and/or chemotherapy (4). Role of external beam radiation, brachytherapy, and chemotherapy What is the role of external beam radiation therapy in …
Immunotherapy Treatment Landscape for Patients With …
Endometrial cancer is the most common gynecologic cancer in the United States. Although most patients with endometrial cancer ... py-free interval of at least 12 months after prior adjuvant …
Original Article Prognostic factors for patients with early-stage ...
https://ejgo.org 1/10 ABSTRACT Objective: Uterine serous carcinoma (USC) is an aggressive type 2 endometrial cancer. Data on prognostic factors for patients with early-stage USC …
Research Paper L1CAM is not a reliable predictor for lymph …
Key words: L1CAM, lymph node metastasis, endometrial cancer, adjuvant therapy, survival Introduction Endometrial cancer is the most common gynaecological cancer in the Western …
Gynaecology Pathway Board - Greater Manchester Cancer
3.7 Endometrial cancer adjuvant therapy 3.8 Endometrial cancer adjuvant chemotherapy 3.9 Adjuvant progestogen treatment 3.10 Primary Radiotherapy 3.11 Treatment algorithm for …
Correlation between pre-operative and final histological …
Ia endometrial cancer with EMG2 without lymphovascular space invasion. The patient did not receive adjuvant therapy, and had no evidence of disease at her last visit after 2 years and 11 …
The Role of Radiotherapy in Endometrial Cancer: Current
Keywords Endometrial cancer.Adjuvant therapy. Radiation therapy.Prognostic factors.Side effects. Quality of life Introduction Endometrial cancer (EC) is the most common gyneco …
Molecular classification in endometrial cancer: opportunities …
Jun 3, 2022 · Endometrial cancer (EC) is common, with 420,000 new cases diagnosed globally each year,1 and it is increasing in both incidence and mortality.1,2 One of the greatest …
BC Cancer Protocol Summary for the Neoadjuvant or …
Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy. J Clin Oncol. 2020 Oct 10;38(29):3388-3397. 3. BC Cancer. …
HIGHLIGHTS OF PRESCRIBING INFORMATION and then …
Non-Small Cell Lung Cancer 1.2 . Small Cell Lung Cancer 1.3. Biliary Tract Cancers 1.4. Hepatocellular Carcinoma 1.5 . Endometrial Cancer 2 DOSAGE AND ADMINISTRATION . 2.1 …
BAGP POLE - British Gynaecological Cancer Society
Apr 8, 2022 · Following the discovery of the four molecular subtypes of endometrial cancer (EC) by The Cancer Genome Atlas (TCGA) ... low-risk and omission of adjuvant therapy should be …
Effect of prior adjuvant radiotherapy on immunotherapy …
Conclusions: In patients with recurrent endometrial cancer who received immuno-therapy, the therapeutic efficacy may be compromised by prior post-operative adjuvant EBRT. WHAT IS …
RESEARCH ARTICLE Open Access Adjuvant chemo …
Recently proposed sequential chemo-radiotherapy as sandwich therapy for high risk endometrial cancer have yielded encouraging results. This article is to review the adjuvant chemo …
Identification of High Risk Subgroups in Endometrial Cancer …
ENDOMETRIAL CANCER (ENDOCA): CANDIDATES FOR TARGET-BASED ADJUVANT THERAPY A. Mariani, M.J. Webb, G.L. Keeney, K.C. Podratz ... hysterectomy and state-of-the …
The role of postoperative radiation therapy for endometrial …
Dec 2, 2013 · endometrial cancer. Methods and materials: Key clinical questions to be addressed in this evidence-based guideline on endometrial cancer were identified. A comprehensive …
Adjuvant chemotherapy and radiation therapy with the …
Conclusion. Our results suggest that adjuvant chemotherapy and radiation therapy with the “sandwich” regimen is associated with acceptable toxicity and satisfactory rates of completion …
The Addition of Adjuvant Chemotherapy to Radiation in Early …
Conclusions: The addition of adjuvant chemotherapy to radiation in HREC is associated with improved OS. Multiple demographic and clinical factors significantly influence the choice of …
NRG Oncology/RTOG Consensus Guidelines for Delineation of …
Endometrial cancer and early stage cervical cancer are treated with surgery with or without adjuvant radiation therapy or chemotherapy.1-7 For endometrial cancer, adju-vant radiation …
Management of histologically confirmed endometrial cancer
followed by adjuvant treatment or radical hysterectomy + B/L Pelvic lymphadenectomy +/- Para aortic lymphadenectomy without adjuvant therapy (if no additional risk factors in the post …
Adjuvant Chemotherapy for Endometrial Cancer
Key Words: Endometrial cancer, Adjuvant chemotherapy, Sequential chemotherapy after radiation Received September 24, 2010, and in revised form January 12, 2011. ... adjuvant therapy is …
