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| endocrine disruptor assessment list: Endocrine Disruption and Human Health Philippa D. Darbre, 2015-03-21 Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations |
| endocrine disruptor assessment list: Challenges in Endocrine Disruptor Toxicology and Risk Assessment Alberto Mantovani, Alexandra Fucic, 2020-12-08 Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology – including interactions with other hormone pathways – has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer’s disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health. |
| endocrine disruptor assessment list: Hormonally Active Agents in the Environment National Research Council, Commission on Life Sciences, Board on Environmental Studies and Toxicology, Committee on Hormonally Active Agents in the Environment, 2000-02-03 Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of estrogen mimics threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€in diet, in pharmaceuticals, from industrial releases into the environmentâ€and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents. |
| endocrine disruptor assessment list: Neuroendocrine Regulation of Animal Vocalization Cheryl S. Rosenfeld, Frauke Hoffmann, 2020-12-04 Neuroendocrine Regulation of Animal Vocalization: Mechanisms and Anthropogenic Factors in Animal Communication examines the underpinning neuroendocrine (NE) mechanisms that drive animal communication across taxa. Written by international subject experts, the book focuses on the importance of animal communication in survival and reproduction at an individual and species level, and the impact that increased production and accumulation of endocrine-disrupting chemicals (EDCs) can have on these regulatory processes. This book discusses sound production, perception, processing, and response across a range of animals. This includes insects, fish, bats, birds, nonhuman primates, infant humans, and many others. Some chapters analyze how neuroactive substances, endocrine control, and chemical pollution affect the physiology of the animal's perceptive and sound-producing organs, as well as their auditory and vocal receptors and pathways. Other chapters address the recent approaches governments have taken to protect against the endocrine disruption of animal (vocal) behaviors. The book is a valuable resource for researchers and advanced students seeking first-rate material on neuroendocrinological effects on animal behavior and communication. - Serves as the most comprehensive cross-taxa study of its kind, revolutionary in its focus on the impacts of EDCs on the processes guiding animal communication - Emphasizes the importance of production, perception and processing of acoustic vocalization for survival - Analyzes recent governmental policies and protections against the effects of EDCs on humans and wildlife |
| endocrine disruptor assessment list: TSCA Lynn L. Bergeson, 2000 |
| endocrine disruptor assessment list: Endocrine Disruptors, Brain, and Behavior Heather B. Patisaul, Scott M. Belcher, 2017-04-10 Our world and bodies are becoming increasingly polluted with chemicals capable of interfering with our hormones and thus, possibly, our present and future neural and mental health. As authors Heather Patisaul and Scott Belcher outline, there is a large lack of data and evidence in this causal relationship, which begs a need for further study to accelerate progress in the endocrinology and neuroendocrinology fields. Endocrine Disruptors, Brain, and Behavior focuses on if and how these chemicals, known as endocrine disrupting compounds (EDCs), affect the development and function of the brain and might be contributing to neural disorders rapidly rising in prevalence. The book provides an overall synthesis of the EDC field, including its historical roots, major hypotheses, key findings, and research gaps. The authors explain why even the concept of endocrine disruption is controversial in some circles, how differing definitions of endocrine disruption and what constitutes an adverse outcome on the brain shape public policy, and where the current capacity by different stakeholders (industry, academia, regulatory agencies) to evaluate chemicals for safety in a regulatory context begins and ends. The book concludes with suggestions for future research needs and a summary of emerging technology which might prove capable of more effectively evaluating existing and emerging chemicals for endocrine disrupting properties. As such, it provides the context for interdisciplinary and innovative input from a broad spectrum of fields, including those well-schooled in neuroscience, evolutionary biology, brain, behavior, sex differences, and neuroendocrinology. |
| endocrine disruptor assessment list: Endocrine-Disrupting Chemicals Andrea C. Gore, 2007-06-08 This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. |
| endocrine disruptor assessment list: Environmental Health Risk Marcelo Larramendy, Sonia Soloneski, 2016-06-16 This book, Environmental Health Risk - Hazardous Factors to Living Species, is intended to provide a set of practical discussions and relevant tools for making risky decisions that require actions to reduce environmental health risk against environmental factors that may adversely impact human health or ecological balances. We aimed to compile information from diverse sources into a single volume to give some real examples extending concepts of those hazardous factors to living species that may stimulate new research ideas and trends in the relevant fields. |
| endocrine disruptor assessment list: Contemporary Endocrinology Sidney H. Ingbar, 2013-03-09 Those who are familiar with the two volumes of The Year in Endocrinology may, at first glance, fail to recognize their relationship to the present volume, Contemporary Endocrinology. The name is different and the cover design different, but nonetheless the admonition against judging a book by its cover is very well taken in this instance. In fact, Contemporary Endocrinology is not only the direct linear descendant of The Year in Endocrinology, it is a purposeful clone thereof-the topics are unchanged, the talented group of authors is unchanged, and most importantly, both the objective of the work and the manner in which that objective is approached are unchanged. The objective is, of course, to assist the reader in maintaining currency with respect to important developments, both basic and clinical, in the major areas of endocrinology. We are all much too familiar, unfortunately, with the difficulty of maintaining currency these days. Our approach to dealing with the informational inflation that we are suffering is similar to that used by economists in dealing with monetary inflation, that is, to increase interest. This we have attempted to do by providing for the reader an easy-to-read group of essays in which advances in individual areas of endocrinology are re viewed broadly, synthesized, and placed into perspective by a group of authors who are authorities in their individual fields. They serve, not as guest artists, but as members of a stable Editorial Board that provides continuity by contributing to successive volumes. |
| endocrine disruptor assessment list: Emerging Chemicals and Human Health Yunhui Zhang, 2020-12-23 This book mainly focuses on advances made over the past 10 years regarding the exposure, metabolism, transformation, toxicity, molecular mechanism and biomarkers for emerging chemicals in humans. A hot topic in the field of environmental health, the term “emerging chemicals” refers to a class of compounds that are frequently encountered and potentially harmful to the natural environment and human health. They are also the preferred target substances for future environmental control measures. The list of emerging chemicals includes pharmaceutical and personal care products (PPCPs), endocrine disruptor chemicals (EDC), persistent organic pollutants (POPs), and nanomaterials. However, the environmental and health hazard characteristics of many emerging chemicals remain unclear. The aim of this book is to stimulate further research in new directions by providing novel and provocative insights into the exposure assessment of and potential mechanisms regarding emerging chemicals in humans. It also offers a state-of-the-art report on recent discoveries concerning emerging chemicals and where the field is headed. |
| endocrine disruptor assessment list: Encyclopedia of Aquatic Ecotoxicology Jean-Francois Férard, Christian Blaise, 2013-06-14 With its 104 chapters, this Encyclopedia of aquatic ecotoxicology reveals the diversity of issues, problems and challenges that have faced, and are facing today, receiving environments. It also indicates ways by which tools, strategies and future investigations can contribute to correct, minimize, solve and prevent water quality degradation. Structured homogeneously, the chapters convey salient information on historical background, features, characteristics, uses and/or applications of treated topics, often complemented by illustrations and case studies, as well as by conclusions and prospects. This work is most suitable for teaching purposes. Academics, for example, could literally deliver comprehensive lectures to students simply based on chapter outlines and contents. Meet the Authors of the Encyclopedia! Check out 'Meet the Authors' under ADDITIONAL INFORMATION (Right menu). |
| endocrine disruptor assessment list: Pediatric and Adolescent Andrology Carlo Foresta, Daniele Gianfrilli, 2021-10-20 This book addresses and summarizes the main andrological disorders (genital, reproductive or sexual diseases) that may originate in childhood or adolescence. Since many of the andrological diseases that occur in adulthood originate before the age of 18 and sometimes even during gestation, andrological evaluation is essential during childhood to highlight anomalies in the genital organs. During puberty, evaluation can help to monitor growth and secondary sex characteristics, and to assess e.g. the possible presence of an eunucoid habitus, gynecomastia, testicular hypotrophy or varicocele, a very common pathology in young people. During adolescence, the assessment of risk factors, such as those related to certain lifestyles, is of fundamental importance for primary prevention. Moreover, in late adolescence the focus shifts to preventing sexually transmitted infections, or to dealing with possible discomforts related to the sexual sphere. Finally, ensuring young people’s genital and sexual health also means protecting their fertility. Written by respected experts in the field, this book constitutes an innovative resource, combining updated, reliable and comprehensive information with agile consultation in order to provide a streamlined approach to the care of children and adolescents with such disorders. |
| endocrine disruptor assessment list: OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 456: H295R Steroidogenesis Assay OECD, 2011-07-28 This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma cell line, used for the assay, expresses genes that ... |
| endocrine disruptor assessment list: Pesticide Policy and Politics in the European Union Emanuela Bozzini, 2017-03-23 This book explores the regulation of pesticides in the European Union in order to reveal the complex, controversial, and contested nature of an assessment system proudly declared by the EU to be ‘the strictest in the world’. The current regulatory framework is based on Regulation 1107/2009, which substantially reformed the previous system. The analysis describes the new criteria and procedures for the authorization of active substances to be used in the production of pesticides, traces the lengthy policy formulation process, and identifies factors that made policy change possible. Further, the book illustrates the current controversies that characterise the implementation of Regulation 1107/2009: the ban of pesticides harmful to pollinators, the renewal of the authorization of glyphosate, and the definition of criteria for the assessment of endocrine disruption. The author provides information on policy outcomes and highlights persisting shortcomings in the enforcement of EU regulation. This book will appeal to students and scholars from a variety of disciplines, including political science, political sociology, and public policy. |
| endocrine disruptor assessment list: Toxicological Profile for Lead , 2007 |
| endocrine disruptor assessment list: Female Puberty Jennifer E. Dietrich, 2014-06-18 Female Puberty: A Comprehensive Guide for Clinicians is a practical reference, covering the full range of issues related to pubertal development. Developed to answer pointed clinical questions and to provide a thorough review of the literature, the book covers both the basics and the complexities of puberty, encompassing psychosocial development to pubertal nuances in highly specialized populations. Comprehensive in scope, this title offers concepts that are concisely conveyed and chapters that complement each other well. Complex subjects such as details of the hypothalamic-pituitary-ovarian axis are covered in a readily understandable manner and bullet points throughout the text serve as helpful reminders to the reader. An invaluable contribution to the literature, Female Puberty: A Comprehensive Guide for Clinicians will be of great interest to all health providers concerned with female reproductive health – including obstetrician gynecologists, reproductive endocrine specialists, pediatricians, pediatric specialists, family practitioners and allied health professionals. |
| endocrine disruptor assessment list: Sex Differences in Physiology Gretchen Neigh, Megan Mitzelfelt, 2016-05-10 Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases |
| endocrine disruptor assessment list: Hormone Signaling Vincent Goffin, Paul A. Kelly, 2002-03-31 Multicellular organisms require a means of intracellular communication to organize and develop the complex body plan that occurs during embryogenesis and then for cell and organ systems to access and respond to an ever changing environmental milieu. Mediators of this constant exchange of information are growth factors, neurotransmmitters, peptide and protein hormones which bind to cell surface receptors and transduce their signals from the extracellular space to the intracellular compartment. Via multiple signaling pathways, receptors of this general class affect growth, development and differentiation. Smaller hydrophobic signaling molecules, such as steroids and non-steroid hormones, vitamins and metabolic mediators interact with a large family of nuclear receptors. These receptors function as transcription factors affecting gene expression, to regulate the multiple aspects of animal and human physiology, including development, reproduction and homeostasis. The aim of this book is to cover various aspects of intracellular signaling involving hormone receptors. |
| endocrine disruptor assessment list: The Promise of Adolescence National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Division of Behavioral and Social Sciences and Education, Board on Children, Youth, and Families, Committee on the Neurobiological and Socio-behavioral Science of Adolescent Development and Its Applications, 2019-07-26 Adolescenceâ€beginning with the onset of puberty and ending in the mid-20sâ€is a critical period of development during which key areas of the brain mature and develop. These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to form relationships with peers and adults, and to explore one's developing identity. It is also a period of resilience that can ameliorate childhood setbacks and set the stage for a thriving trajectory over the life course. Because adolescents comprise nearly one-fourth of the entire U.S. population, the nation needs policies and practices that will better leverage these developmental opportunities to harness the promise of adolescenceâ€rather than focusing myopically on containing its risks. This report examines the neurobiological and socio-behavioral science of adolescent development and outlines how this knowledge can be applied, both to promote adolescent well-being, resilience, and development, and to rectify structural barriers and inequalities in opportunity, enabling all adolescents to flourish. |
| endocrine disruptor assessment list: Sicker, Fatter, Poorer Leonardo Trasande, 2019 A leading voice in public health policy and top environmental medicine scientist reveals the alarming truth about how hormone-disrupting chemicals are affecting our daily lives--and what we can do to protect ourselves and fight back. Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we've turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Dr. Trasande exposes the chemicals that disrupt our hormonal systems and damage our health in irreparable ways. He shows us where these chemicals hide--in our homes, our schools, at work, in our food, and countless other places we can't control--as well as the workings of policy that protects the continued use of these chemicals in our lives. Drawing on extensive research and expertise, he outlines dramatic studies and emerging evidence about the rapid increases in neurodevelopmental, metabolic, reproductive, and immunological diseases directly related to the hundreds of thousands of chemicals that we are exposed to every day. Unfortunately, nowhere is safe. But, thanks to Dr. Trasande's work on the topic, and his commitment to effecting change, this book can help. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he shows us what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve. |
| endocrine disruptor assessment list: Toxicological Profile for 1,3-butadiene , 1992 |
| endocrine disruptor assessment list: Endocrine Disrupting Chemicals-induced Metabolic Disorders and Treatment Strategies Muhammad Sajid Hamid Akash, Kanwal Rehman, Muhammad Zaffar Hashmi, 2021-08-06 This volume offers a detailed and comprehensive analysis of Endocrine Disrupting Chemicals (EDCs), covering their occurrence, exposure to humans and the mechanisms that lead to the parthogenesis of EDCs-induced metabolic disorders. The book is divided into three parts. Part I describes the physiology of the human endocrine system, with special emphasis on various types of metabolic disorders along with risk factors that are responsible for the development of these disorders. Part II addresses all aspects of EDCs, including their role in the induction of various risk factors that are responsible for the development of metabolic disorders. Part III covers up-to-date environmental regulatory considerations and treatment strategies that have been adopted to cure and prevent EDCs-induced metabolic disorders. This section will primarily appeal to clinicians investigating the causes and treatment of metabolic disorders. The text will also be of interest to students and researchers in the fields of Environmental Pharmacology and Toxicology, Environmental Pollution, Pharmaceutical Biochemistry, Biotechnology, and Drug Metabolism/Pharmacokinetics. |
| endocrine disruptor assessment list: Transformation Products of Emerging Contaminants in the Environment Dimitra A. Lambropoulou, Leo M. L. Nollet, 2014-03-17 Over the last 15 years, the focus of chemical pollution has shifted from conventional pollutants to so-called “emerging” or “new” unregulated contaminants. These include pharmaceuticals and personal care products, hormones, UV filters, perfluorinated compounds, poylybrominated flame retardants (BFRs), pesticides, plasticizers, artificial sweeteners, illicit drugs, and endocrine disruptor compounds (EDCs). Despite the increasing number of published studies covering emerging contaminants, we know almost nothing about the effects of their transformation products and/or metabolites. This two-volume set provides a unique collection of research on transformation products, their occurrence, fate and risks in the environment. It contains 32 chapters, organised into 7 parts, each with a distinct focus: • General Considerations • Transformation Processes and Treatment Strategies • Analytical Strategies • Occurrence, Fate and Effects in the Environment • Global Speciality and Environmental Status • Risk Assessment, Management and Regulatory Framework • Outlook Transformation Products of Emerging Contaminants in the Environment is a valuable resource for researchers and industry professionals in environmental chemistry, analytical chemistry, ecotoxicology, environmental sciences, and hydrology, as well as environmental consultants and regulatory bodies. |
| endocrine disruptor assessment list: OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 231: Amphibian Metamorphosis Assay OECD, 2009-09-08 This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ... |
| endocrine disruptor assessment list: The Honest Broker Roger A. Pielke, Jr, 2007-04-19 Scientists have a choice concerning what role they should play in political debates and policy formation, particularly in terms of how they present their research. This book is about understanding this choice, what considerations are important to think about when deciding, and the consequences of such choices for the individual scientist and the broader scientific enterprise. Rather than prescribing what course of action each scientist ought to take, the book aims to identify a range of options for individual scientists to consider in making their own judgments about how they would like to position themselves in relation to policy and politics. Using examples from a range of scientific controversies and thought-provoking analogies from other walks of life, The Honest Broker challenges us all - scientists, politicians and citizens - to think carefully about how best science can contribute to policy-making and a healthy democracy. |
| endocrine disruptor assessment list: Green Chemistry and Water Remediation: Research and Applications Sanjay K. Sharma, 2020-10-22 Green Chemistry and Water Remediation: Research and Applications explores how integrating the principles of green chemistry into remediation research and practice can have a great impact from multiple directions. This volume reviews both common sources of chemical pollution and how using green chemistry as the basis for new or improved remediation techniques can ensure that remediation itself is conducted in a sustainable way. By outlining the main types of chemical pollutants in water and sustainable ways to address them, the authors hope to help chemists identify key areas and encourage them to integrate green chemistry into the design of new processes and products. In addition, the books highlights and encourages the use of the growing range of green remediation approaches available to experts, helping researchers, planners and managers make informed decisions in their selection of remediation techniques. - Puts the naturally-aligned fields of green chemistry and environmental remediation in context, providing key background to both - Highlights the use of both established and cutting-edge techniques for sustainable water remediation, including nanotechnology, biofiltration and phytoremediation - Explores the potential impact sustainability goals in chemical waste production and water remediation |
| endocrine disruptor assessment list: Dioxins and Health A. Schecter, 1994-12-31 This book originated in a series of cross-disciplinary conversations in the years 1984-1990 between the editor, who is a physician-researcher involved in clinical and laboratory research, and a dioxin toxicologist. During the years in which the conversations took place, an extraordinary amount of new scientific literature was published related to dioxins, defined for purposes of this text as the chlorinated dibenzo-p-dioxins, dibenzofurans, polychlorinated biphe nyls (PCB's) and other compounds that are structurally and toxicologically similar to 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7 ,8-TCDD), the most extensively studied and most toxic of this group of chemicals. Dioxins also began to interest not only chemists and toxicologists, but also specialists from diverse disciplines such as wildlife and environmental science, immunology, neuroscience,public health, epidemiology, med icine, government, law, sociology, and journalism. Specialists from such varied disciplines, while familiar with their own literature, frequently did not have time to follow the dioxin literature outside their specialty area. In addition, each specialty had unique knowledge, methods, and perspectives. Cross disciplinary conversation was necessary, but all too frequently, specialists from the various disciplines did not speak the same language, resulting in misunderstanding. |
| endocrine disruptor assessment list: Hypospadias and Genital Development Laurence S. Baskin, 2004 This book focuses on the current basic science research of hypospadias and genital development. Congenital anomalies of the genitalia are the second most common birth abnormality besides congenital heart defects. Genital anomalies come in many varieties with the most common abnormality being hypospadias. The etiology of hypospadias remains unknown and the incidence is doubling in western countries with no definable explanation. It therefore seems especially germane to study this common congenital anomaly with a baseline incidence of 1/125-250 newborn males. |
| endocrine disruptor assessment list: Behavioral Toxicology Bernard Weiss, 2013-03-09 Behavioral toxicology is a young discipline in the United States; so young, in fact, that this is one of its first books. Behavioral questions are bound to play a major role in future scientific work and governmental decisions involving the health effects of environmental contaminants and other chemicals. This role springs from two key problems that face scientists and public agencies required to set acceptable exposure standards or to determine criteria for the toxicity of therapeutic chemicals: How do you evaluate effects that may show up only as subtle functional disturbances? And how do you de tect toxic effects early enough so that they may still be reversible, before they produce major damage? The contributions in this book come from a collection of scientists whose interests span a wide variety of problem areas. The focus is largely on me thodological issues because they represent the most immediate concern of the discipline. We expect that this collection of papers will represent a useful source book for behavioral toxicology for some time. For the past few years, the University of Rochester's Department of Radiation Biology and Biophysics has sponsored a series of international conferences on chemical toxicity, partly as a response to concern over the con sequences to health of the rich chemical soup in which we live. This book is based upon presentations made to the fifth of the series. Held in June, 1972, it was the first formal meeting devoted to behavioral toxicology in this country. |
| endocrine disruptor assessment list: Handbook of Toxicologic Pathology Wanda M. Haschek, Colin George Rousseaux, Matthew A. Wallig, 2002 In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the practice toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury.- |
| endocrine disruptor assessment list: Toxicological Profile for Chlorinated Dibenzo-p-dioxins , 1998 |
| endocrine disruptor assessment list: Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, International Agency for Research on Cancer, 2013 This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents. |
| endocrine disruptor assessment list: Endocrine Disruptors in the Irish Aquatic Environment (2000-MS-2-M1) Heloise Tarrant, 2006 |
| endocrine disruptor assessment list: Anatomy and Physiology J. Gordon Betts, Peter DeSaix, Jody E. Johnson, Oksana Korol, Dean H. Kruse, Brandon Poe, James A. Wise, Mark Womble, Kelly A. Young, 2013-04-25 |
| endocrine disruptor assessment list: Recent updates in molecular Endocrinology and Reproductive Physiology of Fish Jitendra Kumar Sundaray, Mohd Ashraf Rather, Sujit Kumar, Deepak Agarwal, 2022-01-28 This book is dedicated to present different aspects of reproductive physiology and molecular endocrinology of commercially important as well as potential aquaculture fish species. The existing aquaculture generation is looking for species diversification for efficient utilization of available diverse water resources. The knowledge of reproductive physiology of fish will help in development of breeding strategy for use in commercial aquaculture. Reproductive system is highly coordinated and governed by means of complex network of nervous, endocrine system and environmental factor as well. This book emphasize on different key aspects of reproductive endocrine system such as basic gonadal biology in the events of climate vulnerability, sex determination, sex reversal, stimulatory hormones, inhibitory hormones and receptors, environmental and chemical factor guiding reproduction, puberty, neuroendocrine regulation of reproduction etc. This book further describes how reproduction is not just indispensable for the existence or survival of an individual, but it is important for the survival of species. Chapters also address the concerns of anthropogenic activities on fish and the aquatic environment lead main trouble on physiological and reproductive processes of aquatic animals. This book offers an attractive compilation of highly relevant aspects of current and future of aquaculture, especially in view of the growing awareness of aquaculture, to food scientists working on commercial fish, animal biologists, fish geneticists etc. This book is very timely, and relevant to the sustainable development goals. The contents would be relevant to policy makers, working towards blue revolution and blue economy. |
| endocrine disruptor assessment list: Hayes' Principles and Methods of Toxicology A. Wallace Hayes, Tetyana Kobets, 2023-07-03 Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. Principles of Toxicology), major classes of established chemical hazards (Section II. Agents), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. Methods), as well as toxicology of specific target systems and organs (Section IV. Organ- and System-Specific Toxicology). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment. |
| endocrine disruptor assessment list: Magnetic Nanomaterials in Analytical Chemistry Mazaher Ahmadi, Abbas Afkhami, Tayyebeh Madrakian, 2021-04-30 Magnetic Nanomaterials in Analytical Chemistry provides the first comprehensive review of magnetic nanomaterials in a variety of analytical chemistry applications, including basic information necessary for students and those new to the topic to utilize them. In addition to analytical chemists, those in various other disciplines where these materials have great potential-e.g., organic chemistry, catalysis, sensors-will also find this a valuable resource. Magnetic nanomaterials that can be controlled using external magnetic fields have opened new doors for the development of new sample preparation methods and novel magnetic sorbents for forensic chemistry, environmental monitoring, magnetic digital microfluidics, bioanalysis, and food analysis. In addition, they are seeing wide application as sensing materials in the development of giant magnetoresistive sensors, biosensors, electrochemical sensors, surface-enhanced Raman spectroscopy sensors, resonance light scattering sensors, and colorimetric sensors. Includes fundamental information on magnetic nanomaterials, including their classification, synthesis, functionalization, and characterization methods, separation and isolation techniques, toxicity, fate, and safe disposal Each chapter describes a specific application Utilizes figures, schemes, and images for better understanding of the principles of the method Presents information on advanced methods, such as giant magnetoresistive and magnetic digital microfluidics |
| endocrine disruptor assessment list: Computational Toxicology Orazio Nicolotti, 2018-06-24 This volume explores techniques that are currently used to understand solid target-specific models in computational toxicology. The chapters are divided into four sections and discuss topics such as molecular descriptors, QSAR and read-across; molecular and data modeling techniques to comply with both scientific and regulatory sides; computational toxicology in drug discovery; and strategies on how to predict various human-health toxicology endpoints. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the methods and software tools used, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Computational Toxicology: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this expanding field. |
| endocrine disruptor assessment list: Carcinogenic Potency Database; Endocrine Disruptors L. S. Gold, 2000-03 Papers include: supp. to the carcinogenic potency database (CPD): results of animal bioassays published in 1993 to 1994; supplemental plot of the CPD; workshop on characterizing the effects of endocrine disruptors on human health at environmental exposure levels; an approach to the development of quantitative models to assess the effects of exposure to environmentally relevant levels of endocrine disruptors on homeostasis in adults; evaluating the effects of endocrine disruptors on endocrine function during development; and species, interindividual, and tissue specificity in endocrine signaling. Illustrated. |
| endocrine disruptor assessment list: Sample Handling and Trace Analysis of Pollutants Damia Barcelo, Yolanda Pico, 2024-10-25 Sample Handling and Trace Analysis of Pollutants: Innovations to Determine Organic Contaminants, Second Edition reviews the latest technologies and challenges in trace analysis of environmental pollutants, from selecting the right approach to tips for performing analytic procedures and measuring and reporting results. Written by internationally renowned experts in environmental analysis from 5 continents and edited by leaders in the field, this completely updated and revised volume presents the latest techniques developed over the past 10 years, such as high-resolution mass spectrometry, biosensors and imaging techniques. Important tools for problem-solving in the determination of environmental pollutants are also discussed.Chapters cover emerging pollutants in the environment, such as nanomaterials, microplastics, metabolites and/or transformation products and antimicrobial resistances. Specific sections describe field sampling techniques and sample preparation in environmental matrices: air, water, soil, sediment and biota, focus on passive samplers, cover the determination of these environmental contaminants based on analytical techniques, such as the use of gas chromatography and liquid chromatography coupled to mass spectrometry, immunoassays, and biosensors as well as advanced analytical methods such as imaging techniques. - Discusses techniques ranging from chromatography coupled to mass spectrometry, to emerging areas such as nanotechnology, immunoassays and biosensors - Covers the characteristics, advantages, limitations and potential of each technique and the current strategies in each method's development and validation - Outlines practical solutions to challenging problems in the analysis of pollutants in environmental matrices, including how to combine techniques for improved efficacy |
Endocrine System: What It Is, Function, Organs & Diseases
Nov 22, 2023 · Your endocrine system is in charge of creating and releasing hormones to maintain countless bodily functions. Endocrine tissues include your pituitary gland, thyroid, pancreas and …
Endocrine System: What Is It, Functions, Organs & Conditions
Dec 21, 2023 · The endocrine system helps regulate bodily functions through hormone secretion. Learn about the organs and hormones involved, as well as how they work.
Endocrine Disorders: Types, Causes, Symptoms, and Treatments - WebMD
Mar 7, 2024 · An endocrine system malfunction, caused by genetics, infection, or other factors, can result in various disorders such as diabetes, hyperthyroidism, and polycystic ovarian syndrome …
Endocrine system - Wikipedia
The endocrine system[1] is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target …
The Endocrine System and Glands of the Human Body - WebMD
Aug 28, 2023 · What Is the Endocrine System? The endocrine system is a network of glands in your body that make the hormones that help cells talk to each other. They’re responsible for almost …
Anatomy of the Endocrine System - Johns Hopkins Medicine
The endocrine system is a complex network of glands and organs. It uses hormones to control and coordinate your body's metabolism, energy level, reproduction, growth and development, and …
Endocrine system | Definition, Organs, Function, Structure, …
May 10, 2025 · Endocrine system, any of the systems found in animals for the production of hormones, substances that regulate the functioning of the organism. Such a system may range, …
Human endocrine system | Description, Function, Glands,
human endocrine system, group of ductless glands that regulate body processes by secreting chemical substances called hormones. Hormones act on nearby tissues or are carried in the …
Overview of the Endocrine System - The Merck Manuals
The endocrine system coordinates functioning between different organs through hormones, which are chemicals released into the bloodstream from specific types of cells within endocrine …
Understanding the Endocrine System: A Complete Guide
Intro The endocrine system is a vast and intricate network responsible for regulating numerous physiological functions within the human body. It operates primarily through hormones, which …
Endocrine System: What It Is, Function, Organs & Diseases
Nov 22, 2023 · Your endocrine system is in charge of creating and releasing hormones to maintain countless bodily functions. Endocrine tissues include your pituitary gland, thyroid, …
Endocrine System: What Is It, Functions, Organs & Conditions
Dec 21, 2023 · The endocrine system helps regulate bodily functions through hormone secretion. Learn about the organs and hormones involved, as well as how they work.
Endocrine Disorders: Types, Causes, Symptoms, and Treatments - WebMD
Mar 7, 2024 · An endocrine system malfunction, caused by genetics, infection, or other factors, can result in various disorders such as diabetes, hyperthyroidism, and polycystic ovarian …
Endocrine system - Wikipedia
The endocrine system[1] is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that …
The Endocrine System and Glands of the Human Body - WebMD
Aug 28, 2023 · What Is the Endocrine System? The endocrine system is a network of glands in your body that make the hormones that help cells talk to each other. They’re responsible for …
Anatomy of the Endocrine System - Johns Hopkins Medicine
The endocrine system is a complex network of glands and organs. It uses hormones to control and coordinate your body's metabolism, energy level, reproduction, growth and …
Endocrine system | Definition, Organs, Function, Structure, …
May 10, 2025 · Endocrine system, any of the systems found in animals for the production of hormones, substances that regulate the functioning of the organism. Such a system may …
Human endocrine system | Description, Function, Glands,
human endocrine system, group of ductless glands that regulate body processes by secreting chemical substances called hormones. Hormones act on nearby tissues or are carried in the …
Overview of the Endocrine System - The Merck Manuals
The endocrine system coordinates functioning between different organs through hormones, which are chemicals released into the bloodstream from specific types of cells within endocrine …
Understanding the Endocrine System: A Complete Guide
Intro The endocrine system is a vast and intricate network responsible for regulating numerous physiological functions within the human body. It operates primarily through hormones, which …
