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| endpoint definition in chemistry: Chemistry 2e Paul Flowers, Richard Langely, William R. Robinson, Klaus Hellmut Theopold, 2019-02-14 Chemistry 2e is designed to meet the scope and sequence requirements of the two-semester general chemistry course. The textbook provides an important opportunity for students to learn the core concepts of chemistry and understand how those concepts apply to their lives and the world around them. The book also includes a number of innovative features, including interactive exercises and real-world applications, designed to enhance student learning. The second edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Substantial improvements have been made in the figures, illustrations, and example exercises that support the text narrative. Changes made in Chemistry 2e are described in the preface to help instructors transition to the second edition. |
| endpoint definition in chemistry: Water Chemistry Patrick Brezonik, William Arnold, 2011-03-22 It emphasizes that both equilibrium and kinetic processes are important in aquatic systems. |
| endpoint definition in chemistry: Soil and Environmental Chemistry William F. Bleam, 2016-11-30 Soil and Environmental Chemistry, Second Edition, presents key aspects of soil chemistry in environmental science, including dose responses, risk characterization, and practical applications of calculations using spreadsheets. The book offers a holistic, practical approach to the application of environmental chemistry to soil science and is designed to equip the reader with the chemistry knowledge and problem-solving skills necessary to validate and interpret data. This updated edition features significantly revised chapters, averaging almost a 50% revision overall, including some reordering of chapters. All new problem sets and solutions are found at the end of each chapter, and linked to a companion site that reflects advances in the field, including expanded coverage of such topics as sample collection, soil moisture, soil carbon cycle models, water chemistry simulation, alkalinity, and redox reactions. There is also additional pedagogy, including key term and real-world scenarios. This book is a must-have reference for researchers and practitioners in environmental and soil sciences, as well as intermediate and advanced students in soil science and/or environmental chemistry. - Includes additional pedagogy, such as key terms and real-world scenarios - Supplemented by over 100 spreadsheets to migrate readers from calculator-based to spreadsheet-based problem-solving that are directly linked from the text - Includes example problems and solutions to enhance understanding - Significantly revised chapters link to a companion site that reflects advances in the field, including expanded coverage of such topics as sample collection, soil moisture, soil carbon cycle models, water chemistry simulation, alkalinity, and redox reactions |
| endpoint definition in chemistry: Aqueous Acid-base Equilibria and Titrations Robert De Levie, 1999 This book will give students a thorough grounding in pH and associated equilibria, material absolutely fundamental to the understanding of many aspects of chemistry. It is, in addition, a fresh and modern approach to a topic all too often taught in an out-moded way. This book uses new theoretical developments which have led to more generalized approaches to equilibrium problems; these approaches are often simpler than the approximations which they replace. Acid-base problems are readily addressed in terms of the proton condition, a convenient amalgam of the mass and charge constraints of the chemical system considered. The graphical approach of Bjerrum, Hagg, and Sillen is used to illustrate the orders of magnitude of the concentrations of the various species involved in chemical equilibria. Based on these concentrations, the proton condition can usually be simplified, often leading directly to the value of the pH. In the description of acid-base titrations a general master equation is developed. It provides a continuous and complete description of the entire titration curve, which can then be used for computer-based comparison with experimental data. Graphical estimates of the steepness of titration curves are also developed, from which the practicality of a given titration can be anticipated. Activity effects are described in detail, including their effect on titration curves. The discussion emphasizes the distinction between equilibrium constants and electrometric pH measurements, which are subject to activity corrections, and balance equations and spectroscopic pH measurements, which are not. Finally, an entire chapter is devoted to what the pH meter measures, and to the experimental and theoretical uncertainties involved. |
| endpoint definition in chemistry: Quantitative Chemical Analysis Daniel C. Harris, Chuck Lucy, 2015-05-29 The gold standard in analytical chemistry, Dan Harris’ Quantitative Chemical Analysis provides a sound physical understanding of the principles of analytical chemistry and their applications in the disciplines |
| endpoint definition in chemistry: Principles of Modern Chemistry David W. Oxtoby, 1998-07-01 PRINCIPLES OF MODERN CHEMISTRY has dominated the honors and high mainstream general chemistry courses and is considered the standard for the course. The fifth edition is a substantial revision that maintains the rigor of previous editions but reflects the exciting modern developments taking place in chemistry today. Authors David W. Oxtoby and H. P. Gillis provide a unique approach to learning chemical principles that emphasizes the total scientific process'from observation to application'placing general chemistry into a complete perspective for serious-minded science and engineering students. Chemical principles are illustrated by the use of modern materials, comparable to equipment found in the scientific industry. Students are therefore exposed to chemistry and its applications beyond the classroom. This text is perfect for those instructors who are looking for a more advanced general chemistry textbook. |
| endpoint definition in chemistry: Pharmaceutical Medicine Adrian Kilcoyne, Phil Ambery, Daniel O'Connor, 2013-05-23 The breadth of the pharmaceutical medicine can be daunting, but this book is designed to navigate a path through the speciality. Providing a broad overview of all topics relevant to the discipline of pharmaceutical medicine, it gives you the facts fast, in a user-friendly format, without having to dive through page upon page of dense text. With 136 chapters spread across 8 sections, the text offers a thorough grounding in issues ranging from medicines regulation to clinical trial design and data management. This makes it a useful revision aid for exams as well as giving you a taster of areas of pharmaceutical medicine adjacent to your current role. For healthcare professionals already working in the field, this book offers a guiding hand in difficult situations as well as supplying rapid access to the latest recommendations and guidelines. Written by authors with experience in the industry and drug regulation, this comprehensive and authoritative guide provides a shoulder to lean on throughout your pharmaceutical career. |
| endpoint definition in chemistry: Analytical Chemistry Douglas A. Skoog, F. James Holler, 2000-02 Prepare for exams and succeed in your analytical chemistry course with this comprehensive solutions manual! Featuring worked out-solutions to the problems in ANALYTICAL CHEMISTRY: AN INTRODUCTION, 7th Edition, this manual shows you how to approach and solve problems using the same step-by-step explanations found in your textbook examples. |
| endpoint definition in chemistry: Green Chemistry and Engineering Concepción Jiménez-González, David J. C. Constable, 2011-04-12 The past, present, and future of green chemistry and green engineering From college campuses to corporations, the past decade witnessed a rapidly growing interest in understanding sustainable chemistry and engineering. Green Chemistry and Engineering: A Practical Design Approach integrates the two disciplines into a single study tool for students and a practical guide for working chemists and engineers. In Green Chemistry and Engineering, the authors—each highly experienced in implementing green chemistry and engineering programs in industrial settings—provide the bottom-line thinking required to not only bring sustainable chemistry and engineering closer together, but to also move business towards more sustainable practices and products. Detailing an integrated, systems-oriented approach that bridges both chemical syntheses and manufacturing processes, this invaluable reference covers: Green chemistry and green engineering in the movement towards sustainability Designing greener, safer chemical synthesis Designing greener, safer chemical manufacturing processes Looking beyond current processes to a lifecycle thinking perspective Trends in chemical processing that may lead to more sustainable practices The authors also provide real-world examples and exercises to promote further thought and discussion. The EPA defines green chemistry as the design of chemical products and processes that reduce or eliminate the use or generation of hazardous substances. Green engineering is described as the design, commercialization, and use of products and processes that are feasible and economical while minimizing both the generation of pollution at the source and the risk to human health and the environment. While there is no shortage of books on either discipline, Green Chemistry and Engineering is the first to truly integrate the two. |
| endpoint definition in chemistry: Chemical Toxicity Prediction Mark T. D. Cronin, Judith Madden, Steven Enoch, David Roberts, 2013 The aim of this book is to provide the scientific background to using the formation of chemical categories, or groups, of molecules to allow for read-across i.e. the prediction of toxicity from chemical structure. It covers the scientific basis for this approach to toxicity prediction including the methods to group compounds (structural analogues and / or similarity, mechanism of action) and the tools to achieve this. The approaches to perform read-across within a chemical category are also described. The book will provide concise practical guidance for those wishing to apply these methods (in risk / hazard assessment) and will be illustrated with case studies. Chemical Toxicity Prediction is the first book that addresses the concept of category formation and read-across for toxicity prediction specifically. This topic has really taken off in the past few years due to concerns over dealing with the REACH legislation and also due to the availability of the OECD (Q)SAR Toolbox. Much (lengthy and complex) guidance is available on category formation e.g. from the OECD and, to a lesser extent, the European Chemicals Agency but there is no one single source of information that covers all techniques in a concise user-friendly format. There is a real need for this information as in silico toxicology has come to the fore in recent years, primarily as a result of the EU REACH legislation, but also due to many other drivers e.g. reduction of animal testing, Cosmetics regulation. Category formation is seen as the only practical approach to make rational and transparent predictions for complex (human) toxicological endpoints. The book covers all the areas required to create a robust category and perform read-across. |
| endpoint definition in chemistry: Economical, Political, and Social Issues in Water Resources Omid Bozorg-Haddad, 2021-07-14 Economical, Political, and Social Issues in Water Resources provides a fully comprehensive and interdisciplinary overview of all three factors in their relation to water resources. Economic issues consist of Water accounting, Water economy, Water pricing, Water market, Water bank and bourse. Political issues consist of Water power and hydrogemistry, Water diplomacy and hydropolitics, Water rights and water laws, Water governance and policy, Shared water resources management, Water management systems, and social issues consist of Water and culture, civilization and history, Water quality, hygiene, and health, Water and society. This book familiarizes researchers with all aspects of the field, which can lead to optimized and multidimensional water resources management. Some of abovementioned issues are new, so the other aim of this book is to identify them in order to researchers can easily find them and use them in their studies. - Includes diverse case studies from around the world - Presents contributions from global and diverse contributors with interdisciplinary backgrounds, including water engineers, scientists, planners the economic, political and social issues surrounding water - Contains in-depth definitions and concepts of each topic |
| endpoint definition in chemistry: Comprehensive Medicinal Chemistry III , 2017-06-03 Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs |
| endpoint definition in chemistry: Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics - E-Book Carl A. Burtis, David E. Bruns, 2014-02-26 A condensed, easier-to-understand student version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 7th Edition uses a laboratory perspective in providing the clinical chemistry fundamentals you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry experts Carl Burtis and David Bruns, this textbook shows how to select and perform diagnostic lab tests, and accurately evaluate results. Authoritative, respected author team consists of two well-known experts in the clinical chemistry world. Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing. Learning objectives begin each chapter, providing measurable outcomes to achieve after completing the material. Key words are listed and defined at the beginning of each chapter, and bolded in the text. A glossary at the end of the book makes it quick and easy to look up definitions of key terms. More than 500 illustrations plus easy-to-read tables help you understand and remember key concepts. New chapters on molecular diagnostics include the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field. New content on clinical evaluation of methods, kidney function tests, and diabetes is added to this edition. NEW multiple-choice review questions at the end of each chapter allow you to measure your comprehension of the material. NEW case studies on the Evolve companion website use real-life scenarios to reinforce concepts. |
| endpoint definition in chemistry: Dictionary of Chemistry , |
| endpoint definition in chemistry: Chemistry and Toxicology of Pollution Des W. Connell, Gregory J. Miller, 2023-01-12 Describes the transport of pollutants through the environment and their impact on natural and human systems, fully updated to cover key topics in modern pollution science Chemistry and Toxicology of Pollution examines the interactions and adverse effects of pollution on both natural ecosystems and human health, addressing chemical, toxicological, and ecological factors at both the regional and global scale. The book is written using a conceptual framework that follows the interaction of a pollutant with the environment from distribution in the various abiotic sectors of the environment to exposure and effects on individuals and ecosystems. The authors also highlight the critical role of various socio-economic, political, and cultural aspects in achieving sustainable goals, strategies, and science-based solutions to pollution and health. This comprehensive volume covers the chemical behavior and governing principles of pollutants, their interactions with humans and ecosystems, and the methods and processes of environmental risk assessment and pollution management. Extensively revised and expanded, the second edition equips readers with the knowledge required to help lead the way towards a healthy and sustainable future. New chapters address current pollution issues such as global warming and climate change, recent advances in environmental science, the monitoring and evaluation of new and emerging pollutants, risk assessment and remediation, and innovative pollution management approaches and techniques. With in-depth material on human toxicology integrated throughout the text, Chemistry and Toxicology of Pollution: Provides an effective framework for interpreting the information produced by international, national, and local agencies Presents unifying theories and principles supported by up-to-date scientific literature Offers broad coverage of pollution science with an emphasis on North America, the UK, Europe, China, India, and Australia Discusses the similarities and differences of the impact of pollutants on the natural environment and humans Chemistry and Toxicology of Pollution, Second Edition enables readers to view pollution in its correct perspective and develop appropriate control measures. It is essential reading for scientists, academic researchers, policymakers, professionals working in industry, and advanced students in need of a clear understanding of the nature and effects of environmental pollution. |
| endpoint definition in chemistry: MCAT General Chemistry Review Alexander Stone Macnow, 2016-07-05 The most efficient learning for the MCAT results you want. Kaplan's MCAT General Chemistry Review has all the information and strategies you need to score higher on the MCAT. This book features more practice than any other guide, plus targeted subject-review questions, opportunities for self-analysis, a complete online center, and thorough instruction on all of the general chemistry concepts necessary for MCAT success--from the creators of the #1 MCAT prep course,--page [4] of cover. |
| endpoint definition in chemistry: In Silico Toxicology Mark T. D. Cronin, Judith C. Madden, 2010 This book defines the use of computational approaches to predict the environmental toxicity and human health effects of organic chemicals. |
| endpoint definition in chemistry: Quantitative Chemical Analysis Na Li, John J Hefferren, Ke'an Li, 2013-04-26 This book covers both fundamental and practical aspects of chemical analysis: Data Process and Analysis; Chemical Equilibria and Volumetric titrations; Gravimetry; Spectrophotometry; Sample Preparation and Separation Methods in Quantitative Analysis. It was written with the rich tradition of teaching at Peking University College of Chemistry, and edited by an American professor who was personally sensitive to the needs of students learning science from traditional chemistry textbooks written in English. Many examples and illustrative problems in this text have been taken from previous textbooks by the Peking University Team Teaching Program. The book can be used as a starter in analytical chemistry which is fundamental and the base upon which chemistry is built. Traditional chapters of initial learning in analytical chemistry are included, such as volumetric, gravimetric and separation methods; the book also includes key chapters on problem solving relating to recent progress in analytical chemistry. |
| endpoint definition in chemistry: Life Cycle Impact Assessment Michael Z. Hauschild, Mark A.J. Huijbregts, 2015-03-24 This book offers a detailed presentation of the principles and practice of life cycle impact assessment. As a volume of the LCA compendium, the book is structured according to the LCIA framework developed by the International Organisation for Standardisation (ISO)passing through the phases of definition or selection of impact categories, category indicators and characterisation models (Classification): calculation of category indicator results (Characterisation); calculating the magnitude of category indicator results relative to reference information (Normalisation); and converting indicator results of different impact categories by using numerical factors based on value-choices (Weighting). Chapter one offers a historical overview of the development of life cycle impact assessment and presents the boundary conditions and the general principles and constraints of characterisation modelling in LCA. The second chapter outlines the considerations underlying the selection of impact categories and the classification or assignment of inventory flows into these categories. Chapters three through thirteen exploreall the impact categories that are commonly included in LCIA, discussing the characteristics of each followed by a review of midpoint and endpoint characterisation methods, metrics, uncertainties and new developments, and a discussion of research needs. Chapter-length treatment is accorded to Climate Change; Stratospheric Ozone Depletion; Human Toxicity; Particulate Matter Formation; Photochemical Ozone Formation; Ecotoxicity; Acidification; Eutrophication; Land Use; Water Use; and Abiotic Resource Use. The final two chapters map out the optional LCIA steps of Normalisation and Weighting. |
| endpoint definition in chemistry: State Estimation in Chemometrics Pierre C. Thijssen, 2008-02-28 This unique text blends together state estimation and chemometrics for the application of advanced data-processing techniques. It further applies system theory in order to develop a modular framework to be implemented on computer for the development of simple intelligent analyzers. Short reviews on the history of state estimation and chemometrics are given, together with examples of the applications described, including classical estimation, state estimation, non-linear estimation, the multi-component, calibration and titration systems and the Kalman filter. The contents are very systematic and build the ideas up logically to appeal to specialist post-graduates working in this area, together with professionals in other areas of chemistry and engineering. - Blends together state estimation and chemometrics for the application of advanced data-processing techniques - Provides short reviews on the history of state estimation and chemometrics, together with examples of the applications described |
| endpoint definition in chemistry: Practical Aspects of Computational Chemistry Jerzy Leszczynski, Manoj Shukla, 2009-10-03 Practical Aspects of Computational Chemistry presents contributions on a range of aspects of Computational Chemistry applied to a variety of research fields. The chapters focus on recent theoretical developments which have been used to investigate structures and properties of large systems with minimal computational resources. Studies include those in the gas phase, various solvents, various aspects of computational multiscale modeling, Monte Carlo simulations, chirality, the multiple minima problem for protein folding, the nature of binding in different species and dihydrogen bonds, carbon nanotubes and hydrogen storage, adsorption and decomposition of organophosphorus compounds, X-ray crystallography, proton transfer, structure-activity relationships, a description of the REACH programs of the European Union for chemical regulatory purposes, reactions of nucleic acid bases with endogenous and exogenous reactive oxygen species and different aspects of nucleic acid bases, base pairs and base tetrads. |
| endpoint definition in chemistry: Practical Data Analysis in Chemistry Marcel Maeder, Yorck-Michael Neuhold, 2007-08-10 The majority of modern instruments are computerised and provide incredible amounts of data. Methods that take advantage of the flood of data are now available; importantly they do not emulate 'graph paper analyses' on the computer. Modern computational methods are able to give us insights into data, but analysis or data fitting in chemistry requires the quantitative understanding of chemical processes. The results of this analysis allows the modelling and prediction of processes under new conditions, therefore saving on extensive experimentation. Practical Data Analysis in Chemistry exemplifies every aspect of theory applicable to data analysis using a short program in a Matlab or Excel spreadsheet, enabling the reader to study the programs, play with them and observe what happens. Suitable data are generated for each example in short routines, this ensuring a clear understanding of the data structure. Chapter 2 includes a brief introduction to matrix algebra and its implementation in Matlab and Excel while Chapter 3 covers the theory required for the modelling of chemical processes. This is followed by an introduction to linear and non-linear least-squares fitting, each demonstrated with typical applications. Finally Chapter 5 comprises a collection of several methods for model-free data analyses.* Includes a solid introduction to the simulation of equilibrium processes and the simulation of complex kinetic processes.* Provides examples of routines that are easily adapted to the processes investigated by the reader* 'Model-based' analysis (linear and non-linear regression) and 'model-free' analysis are covered |
| endpoint definition in chemistry: Chemical-Mechanical Planarization of Semiconductor Materials M.R. Oliver, 2013-03-14 This book contains a comprehensive review of CMP (Chemical-Mechanical Planarization) technology, one of the most exciting areas in the field of semiconductor technology. It contains detailed discussions of all aspects of the technology, for both dielectrics and metals. The state of polishing models and their relation to experimental results are covered. Polishing tools and consumables are also covered. The leading edge issues of damascene and new dielectrics as well as slurryless technology are discussed. |
| endpoint definition in chemistry: Holt McDougal Modern Chemistry Mickey Sarquis, 2012 |
| endpoint definition in chemistry: Green Toxicology Alexandra Maertens, 2022-02-01 Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists. |
| endpoint definition in chemistry: Chemistry Steven S. Zumdahl, 1993 |
| endpoint definition in chemistry: Management of Animal Care and Use Programs in Research, Education, and Testing Robert H. Weichbrod, Gail A. (Heidbrink) Thompson, John N. Norton, 2017-09-07 AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology). |
| endpoint definition in chemistry: OECD Series on Testing and Assessment Guidance Document on the Validation of (Quantitative) Structure-Activity Relationship [(Q)SAR] Models OECD, 2014-09-03 This document presents principles and helpful guides for validating (Q)SAR technology for a variety of applications. |
| endpoint definition in chemistry: Encyclopedia of Analytical Science Alan Townshend, Colin F. Poole, 2005-01-10 As with the first edition of the Encyclopedia of Analytical Science, Second Edition is designed to provide a detailed and comprehensive publication covering all facets of the science and practice of analysis. The new work has been extensively revised in terms of the titles and content of the first edition, and includes comprehensive coverage of techniques used for the determination of specific elements, compounds and groups of compounds, in physical or biological matrices. It addresses applications of chemical analysis in all areas, ranging from such topics as medicine to environmental science, and geology to food science. Important characterisation techniques, such as microscopy and surface analysis are also included. The complete work consists of around 610 articles, each consisting of about 4000 words, figures and summary tables. These articles are combined to form larger entries providing comprehensive coverage of important topics and assisting the reader in locating material of interest. The entries are arranged in an A to Z format providing a final publication of about two and a half million words in ten volumes. The articles are structured to allow easy access to information on specific analytes, instrumental techniques and sample matrices. There is extensive cross-referencing throughout the Encyclopedia and a detailed index. Also available online via ScienceDirect - featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. Comprehensive in coverage Meticulously organised Clearly written |
| endpoint definition in chemistry: Matter and Method in the Long Chemical Revolution Victor D. Boantza, 2016-05-06 The seventeenth-century scientific revolution and the eighteenth-century chemical revolution are rarely considered together, either in general histories of science or in more specific surveys of early modern science or chemistry. This tendency arises from the long-held view that the rise of modern physics and the emergence of modern chemistry comprise two distinct and unconnected episodes in the history of science. Although chemistry was deeply transformed during and between both revolutions, the scientific revolution is traditionally associated with the physical and mathematical sciences whereas modern chemistry is seen as the exclusive product of the chemical revolution. This historiographical tension, between similarity in ’form’ and disparity in historical ’content’ of the two events, has tainted the way we understand the rise of modern chemistry as an integral part of the advent of modern science. Against this background, Matter and Method in the Long Chemical Revolution examines the role of and effects on chemistry of both revolutions in parallel, using chemistry during the chemical revolution to illuminate chemistry during the scientific revolution, and vice versa. Focusing on the crises and conflicts of early modern chemistry (and their retrospectively labeled ’losing’ parties), the author traces patterns of continuity in matter theory and experimental method from Boyle to Lavoisier, and reevaluates the disciplinary relationships between chemists, mechanists, and Newtonians in France, England, and Scotland. Adopting a unique approach to the study of the scientific and chemical revolutions, and to early modern chemical thought and practice in particular, the author challenges the standard revolution-centered history of early modern science, and reinterprets the rise of chemistry as an independent discipline in the long eighteenth century. |
| endpoint definition in chemistry: A Framework for K-12 Science Education National Research Council, Division of Behavioral and Social Sciences and Education, Board on Science Education, Committee on a Conceptual Framework for New K-12 Science Education Standards, 2012-02-28 Science, engineering, and technology permeate nearly every facet of modern life and hold the key to solving many of humanity's most pressing current and future challenges. The United States' position in the global economy is declining, in part because U.S. workers lack fundamental knowledge in these fields. To address the critical issues of U.S. competitiveness and to better prepare the workforce, A Framework for K-12 Science Education proposes a new approach to K-12 science education that will capture students' interest and provide them with the necessary foundational knowledge in the field. A Framework for K-12 Science Education outlines a broad set of expectations for students in science and engineering in grades K-12. These expectations will inform the development of new standards for K-12 science education and, subsequently, revisions to curriculum, instruction, assessment, and professional development for educators. This book identifies three dimensions that convey the core ideas and practices around which science and engineering education in these grades should be built. These three dimensions are: crosscutting concepts that unify the study of science through their common application across science and engineering; scientific and engineering practices; and disciplinary core ideas in the physical sciences, life sciences, and earth and space sciences and for engineering, technology, and the applications of science. The overarching goal is for all high school graduates to have sufficient knowledge of science and engineering to engage in public discussions on science-related issues, be careful consumers of scientific and technical information, and enter the careers of their choice. A Framework for K-12 Science Education is the first step in a process that can inform state-level decisions and achieve a research-grounded basis for improving science instruction and learning across the country. The book will guide standards developers, teachers, curriculum designers, assessment developers, state and district science administrators, and educators who teach science in informal environments. |
| endpoint definition in chemistry: General Chemistry Ralph H. Petrucci, F. Geoffrey Herring, Jeffry D. Madura, Carey Bissonnette, 2010-05 |
| endpoint definition in chemistry: Drug-like Properties: Concepts, Structure Design and Methods Li Di, Edward H Kerns, 2010-07-26 Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint |
| endpoint definition in chemistry: Exploring General Chemistry in the Laboratory Colleen F. Craig, Kim N. Gunnerson, 2017-02-01 This laboratory manual is intended for a two-semester general chemistry course. The procedures are written with the goal of simplifying a complicated and often challenging subject for students by applying concepts to everyday life. This lab manual covers topics such as composition of compounds, reactivity, stoichiometry, limiting reactants, gas laws, calorimetry, periodic trends, molecular structure, spectroscopy, kinetics, equilibria, thermodynamics, electrochemistry, intermolecular forces, solutions, and coordination complexes. By the end of this course, you should have a solid understanding of the basic concepts of chemistry, which will give you confidence as you embark on your career in science. |
| endpoint definition in chemistry: Modern Analytical Chemistry David Harvey, 2000 This introductory text covers both traditional and contemporary topics relevant to analytical chemistry. Its flexible approach allows instructors to choose their favourite topics of discussion from additional coverage of subjects such as sampling, kinetic method, and quality assurance. |
| endpoint definition in chemistry: Chemistry for the Biosciences Jonathan Crowe, Tony Bradshaw, 2014 Leading students through the essential concepts that are central to understanding biological systems, this text uses everyday examples and analogies to build their confidence in an often daunting subject. By focusing on the key themes that unify the subject, it shows how integral chemistry is to the biosciences |
| endpoint definition in chemistry: Management Principles of Sustainable Industrial Chemistry Genserik L. L. Reniers, Kenneth Sörensen, Karl Vrancken, 2013-03-20 Approaching sustainability from the perspectives of engineering and multiple scientific disciplines, this book incorporates the concepts of intergenerational equity and ecological capabilities, while promoting scientific rigor for the analysis of sustainability and the use of appropriate metrics to determine the comparative merits of alternatives. The chapters are organized around the key non-technological themes of sustainable industrial chemistry and provide an overview of the managerial principles to enhance sustainability in the chemicals sector. The book strives to provide an intellectual forum and stimulus for defining the roles chemical engineers can play in achieving sustainable development. Suitable for industry and graduate education, this is the one-stop guide to greener, cleaner, economically viable and more efficient chemical industries. |
| endpoint definition in chemistry: Chemical Structure, Spatial Arrangement Peter J. Ramberg, 2017-05-15 Offering a comprehensive narrative of the early history of stereochemistry, Dr Ramberg explores the reasons for and the consequences of the fundamental change in the meaning of chemical formulas with the emergence of stereochemistry during the last quarter of the nineteenth century. As yet relatively unexplored by historians, the development of stereochemistry - the study of the three-dimensional properties of molecules - provides a superb case study for exploring the meaning and purpose of chemical formulas, as it entailed a significant change in the meaning of chemical formulas from the purely chemical conception of 'structure' to the physico-chemical conception of molecules provided by the tetrahedral carbon atom. This study is the first to treat the emergence of the unique visual language of organic chemistry between 1830 and 1874 to place in context the near simultaneous proposal of the tetrahedral carbon atom by J.H. van 't Hoff and J.A. Le Bel in 1874. Dr Ramberg then examines the research programs in stereochemistry by Johannes Wislicenus, Arthur Hantzsch, Victor Meyer, Carl Bischoff, Emil Fischer and Alfred Werner, showing how the emergence of stereochemistry was a logical continuation of established research traditions in chemistry. In so doing, he also illustrates the novel and controversial characteristics of stereochemical ideas, especially the unprecedented use of mechanistic and dynamic principles in chemical explanation. |
| endpoint definition in chemistry: Analytical Chemistry Victor Angelo Soffiantini, 2021-10-11 The textbook is based on the APPLIED use of laboratory instrumentation and apparatus in practice in the real working world with absolute minimum use of complex calculations and mathematics. Instrumental theory is kept to a minimum, with useful practical hints and unbiased instruction on lab instruments’ capabilities and operations. All text is in simple to understand language of the complexities of chemical analyses. |
| endpoint definition in chemistry: Applied Complexometry Rudolf Přibil, 2013-10-22 Applied Complexometry tackles complexometry from a practical perspective. The book discusses more applications, and theories are reduced to the most important ones. Comprised of 22 chapters, this book deals first with volumetric reagents in complexometry, and then tackles detection of the titration end-point. Chapter 3 covers masking (screening) reagents. Chapter 4 discusses separation methods, and Chapter 5 covers apparatus and solutions. Chapter 6 talks about the classification of EDTA complexes, while Chapter 7 discusses the complexometry anions. Chapter 8 discusses the analytical applications; Chapters 9 to 21 explain the analysis of several materials and solutions, such as alloys, silicates and rocks, cement, ores and concentrates, semiconductors, pigments, and electroplating solutions. The last chapter discusses further applications of complexometry. This book will be of great interest to researchers, especially for chemists whose work involves various chemical techniques such as complexometry. |
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however, any major modifications of the primary endpoint definition or its analysis will also be reflected in a protocol amendment. 2.1. Study Objectives 2.1.1. Primary Objectives: • To …
