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| engineering precision nanoparticles for drug delivery: Nanostructures for the Engineering of Cells, Tissues and Organs Alexandru Mihai Grumezescu, 2018-02-14 Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries. - Explains how nanomaterials regulate different cell behavior and function as a carrier for different biomolecules - Shows how nanobiomaterials and nanobiodevices are used in a range of treatment areas, such as skin tissue, wound healing and bone regeneration - Discusses nanomaterial preparation strategies for pharmaceutical application and regenerative medicine |
| engineering precision nanoparticles for drug delivery: The Road from Nanomedicine to Precision Medicine Shaker A. Mousa, Raj Bawa, Gerald F. Audette, 2020-01-17 The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book’s multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government. |
| engineering precision nanoparticles for drug delivery: Silk-based Drug Delivery Systems Elia Bari, Sara Perteghella, Maria Luisa Torre, 2020-10-05 Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin. |
| engineering precision nanoparticles for drug delivery: Engineered Nanoparticles as Drug Delivery Systems Nahid Rehman, Anjana Pandey, 2022-12-30 This book highlights application of nanomaterials for drug delivery, therapy, and engineering. It covers stimuli-sensitive drug delivery systems including an overview of the physical, chemical, biological, and multi-stimuli-responsive nanosystems. It also presents analysis of clinical status for different types of nanoplatforms and assesses novel applications of nanomaterials in the areas of smart delivery and drug targeting. It further discusses the advantages and disadvantages of each application of pertinent nanomaterials. Features: Provides academic introduction to the uses of nanotechnology in drug delivery. Discusses use of nanomaterials in targeting a drug to specific tissues and cells. Presents an analysis of clinical status for different types of nanoplatforms. Covers applications in drug delivery, therapy, and engineering. Focuses on how novel nanotechnology-orientated methods can help improve treatment. This book is aimed at researchers and graduate students in biomedical and biochemical engineering, pharmaceutical, chemical and bioprocess engineering, materials science, and drug delivery mechanisms. |
| engineering precision nanoparticles for drug delivery: Intelligent Nanomaterials for Drug Delivery Applications Nabeel Ahmad, Gopinath Packirisamy, 2020-03-29 Intelligent Nanomaterials for Drug Delivery Applications discusses intelligent nanomaterials with a particular focus on commercial and premarket tools. The book looks at the applications of intelligent nanomaterials within the field of medicine and discusses their future role. This includes the use of intelligent nanomaterials for drugs used in cardiovascular and cancer treatments and examines the promising market of nanoparticles for biomedical and biosensing applications. This resource will be of great interest to scientists and researchers involved in multiple disciplines, including micro- and nano-engineering, bionanotechnology, biomedical engineering, and nanomedicine, as well as pharmaceutical and biomedical industries. - Focuses on applications of intelligent nanomaterials within the field of medicine and discusses their role in the future - Discusses intelligent nanomaterials, with a particular focus on commercial and premarket tools - Examines the promising market of nanoparticles for biomedical and biosensing applications |
| engineering precision nanoparticles for drug delivery: NanoFormulation Gordon Tiddy, Gordon J. T. Tiddy, Reginald B. H. Tan, 2012 NanoFormulation covers advances in research, development and applications of innovative formulation technologies where nanomaterials play an essential role. |
| engineering precision nanoparticles for drug delivery: Engineered Biomaterials Rishabha Malviya, Sonali Sundram, 2023-12-28 This book highlights recent advances focusing on the synthesis methods of engineered biomaterials and their applications. The book discusses recent applications of various approaches and technology in improving the functional properties and biological activities of biopolymers. It includes two major sections: the first section introduces a range of methods which lead to materials with enhanced properties for a range of practical applications, along with the positives and limitations of the techniques. The second section covers recent trends and advances in application of engineered biomaterials that assist materials scientists and researchers in mapping out the future of these new improved materials through value addition in order to enhance their use. Contributions in the book are done by prominent researchers from industry, academia, and government/private research laboratories across the globe. The book summarizes in a fairly comprehensive manner many of the recent technical advancements in the area of biopolymers. The book is intended to serve as a reference resource in the area of polymers science. |
| engineering precision nanoparticles for drug delivery: Nanovaccinology Kaushik Pal, 2023-09-23 This book provides an overview of the cumulative work on a driving force for innovation in medicine and modern healthcare, boosting advances in therapeutics, biosensors, vaccines, and clinical systems. The work presented shows how nanoparticles have been investigated as vaccine adjuvants because they possess chemical and structural properties that improve immunogenicity as well as the use of nanotechnology in the construction of immunization systems that has developed into the field of viral nanovaccinology. The volume highlights potential areas of research, innovation, and development of finished products for future commercialization and significant research exploration through nanoparticles that prove capable of surmounting most of the barriers like toxicity issues, clearance from biological system, DNA instability, and differences in expression systems. The contributing authors review the primary literature on principles, limitations, and recent breakthroughs in nanoparticle-based antigen delivery vehicles, their use in different diseases, the major bottlenecks, and related issues. Highlighting advances in nanoparticle engineering and the understanding of nanoparticle characteristics as well as critical legacy work dome in the field of nanobiotechnology, the book is ideal for a range of researchers and students in the pure and applied sciences devoted to nanomaterials, vaccinology, and translational medicine. |
| engineering precision nanoparticles for drug delivery: Advanced and Modern Approaches for Drug Delivery Amit Kumar Nayak, Md Saquib Hasnain, Bibek Laha, Sabyasachi Maiti, 2023-07-29 Advanced and Modern Approaches for Drug Delivery explores novel approaches currently used for drug delivery, including the must up-to-date techniques and technology. The approaches discussed allow pharmaceutical scientists to design effective drug delivery systems or devices for the management and treatment of numerous diseases and conditions. Detailed information on a wide variety of subjects, including dendrimers, lipid nanostructures, solid lipid nanoparticles, stimuli-responsive smart systems, self-assembled protein-drug nanoparticles, nanoconjugate formulations, nanofibers, iontophoretic systems, microneedle systems, ultra-sound triggered systems, targeted carrier-based intracellular delivery systems, resealed erythrocyte-based systems, 3 D-printing tool, site-specific monoclonal antibodies, and bio-inspired systems are all comprehensively discussed. With contributions from those in academia and industry, this book is an excellent reference for all those needing to understand drug delivery systems. - Provides thorough insights into the most up-to-date approaches and technologies for drug delivery and therapeutics - Discusses possible future approaches - Includes perspectives from industry and academia |
| engineering precision nanoparticles for drug delivery: Drug Targeting and Stimuli Sensitive Drug Delivery Systems Alexandru Mihai Grumezescu, 2018-05-21 Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. - Shows how the use of nanomaterials can help target a drug to specific tissues and cells - Explores the development of stimuli-responsive drug delivery systems - Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy |
| engineering precision nanoparticles for drug delivery: 21st Century Surface Science Phuong Pham, Pratibha Goel, Samir Kumar, Kavita Yadav, 2020-11-26 Surface sciences elucidate the physical and chemical aspects of the surfaces and interfaces of materials. Of great interest in this field are nanomaterials, which have recently experienced breakthroughs in synthesis and application. As such, this book presents some recent representative achievements in the field of surface science, including synthesis techniques, surface modifications, nanoparticle-based smart coatings, wettability of different surfaces, physics/chemistry characterizations, and growth kinetics of thin films. In addition, the book illustrates some of the important applications related to silicon, CVD graphene, graphene oxide, transition metal dichalcogenides, carbon nanotubes, carbon nanoparticles, transparent conducting oxide, and metal oxides. |
| engineering precision nanoparticles for drug delivery: Nanotechnology for Drug Delivery and Pharmaceuticals Ravindra Pratap Singh, Kshitij RB Singh, Jay Singh, Charles Oluwaseun Adetunji, 2023-01-10 Nanotechnology for Drug Delivery and Pharmaceutical Sciences presents various drug-delivery techniques that utilize nanotechnology for the biomedical domain, highlighting both therapeutic and diagnostic applications. The book provides important facts and detailed studies on different promising nanocarriers like liposomes, exosomes and virus-based nanocarriers. Moreover, it explores these nanocarriers' utilization in the therapeutic applications of various diseases such as cancer, inflammation, neurodegenerative disorders like Huntington's disease, Alzheimer's disease, human immunodeficiency virus (HIV), and inflammatory bowel disease. In addition, the book describes how nanotechnology has efficiently overtaken conventional dosage forms and provided comfort and ease to patients. Relevant information regarding market trends, patents and social-economic factors are also provided, making this the perfect reference for doctors, researchers and scientists working in the fields of medicine, biochemistry, biotechnology, nanobiotechnology and the pharmaceutical sciences. - Gives a brief description of the utilization of nanotechnology in the drug-delivery domain - Highlights the properties of nanocarriers, their diagnostic and imaging applications, and their potential role in clinical diagnosis - Focuses on future developments and possibilities, allowing readers to enhance and explore the remaining gaps |
| engineering precision nanoparticles for drug delivery: Nanomaterials for Drug Delivery and Neurological Diseases Management Santosh Kumar Rath, |
| engineering precision nanoparticles for drug delivery: Single-Chain Polymer Nanoparticles José A. Pomposo, 2017-08-18 This first book on this important and emerging topic presents an overview of the very latest results obtained in single-chain polymer nanoparticles obtained by folding synthetic single polymer chains, painting a complete picture from synthesis via characterization to everyday applications. The initial chapters describe the synthetics methods as well as the molecular simulation of these nanoparticles, while subsequent chapters discuss the analytical techniques that are applied to characterize them, including size and structural characterization as well as scattering techniques. The final chapters are then devoted to the practical applications in nanomedicine, sensing, catalysis and several other uses, concluding with a look at the future for such nanoparticles. Essential reading for polymer and materials scientists, materials engineers, biochemists as well as environmental chemists. |
| engineering precision nanoparticles for drug delivery: Synthetic Polymers in Drug and Biotherapeutics Delivery Rangasamy Jayakumar, Mar Masson, Deepagan Veerasikku Gopal, 2024-10-01 Synthetic Polymers in Drug and Biotherapeutics Delivery covers new polymers that are fast replacing obsolete polymers in the field of drug delivery. Each chapter focuses on a specific polymer, detailing its design, synthesis, fabrication techniques, and applications in drug and biotherapeutics delivery. Synthetic polymers provide a unique set of opportunities in drug and biotherapeutics delivery due to their chemical versatility and tunable physicochemical properties. Such polymers can be formulated into nanoparticles, nanofibers, nanogels, microparticles, beads, hydrogels, and scaffolds to suit specific needs such as drug release rate, and biodegradation with low toxicity. This book covers new polymers that are fast replacing obsolete polymers in the field of drug delivery. Each chapter will focus on a specific polymer detailing its design, synthesis, fabrication techniques, and applications in drug and biotherapeutics delivery. This book provides a thorough review of the latest research in this rapidly changing field and would be of interest to materials scientists, pharmaceutical scientists, biomedical engineers, chemical engineers, and clinicians with an interest in materials development. - Details the immunological aspects of synthetic polymeric materials, helping the reader prepare for, and even avoid, unwanted side effects of use - Reviews each polymer sub-type, chapter-by-chapter, ensuring thorough coverage and detailed analysis of each - Explores a range of applications in drug and biotherapeutics delivery, including treatments for cardiovascular, neurological and gastrointestinal diseases |
| engineering precision nanoparticles for drug delivery: Nanotechnology and Human Health Mukesh Kumar Yadav, Punuri Jayasekhar Babu, Jae Jun Song, Arun S. Kharat, 2022-11-11 Nanotechnology in Human Health: Current Research and Future Trends details the various challenges faced in human healthcare settings and how nanotechnology can be used to target and improve outcomes. The book describes the application of nanoparticles in the diagnosis of human diseases, including metabolic diseases, cancer, bacterial infection, organ degeneration and the various targeted, nano-based treatments available. Several chapters look at how microbial biofilms - a key clinical concern - can be mitigated using nanomaterials and nanotechnology. In addition, the book covers how different nanoparticle types can be utilized as therapeutic agents. This book combines materials science concepts and techniques with clinical insights and understanding to provide an interdisciplinary reference for materials scientists, microbiologists, biomedical engineers and clinicians with an interest in nanotechnology. - Reviews the potential applications of nanotechnology in healthcare, with a focus on combating antibiotic-resistant microbial infections and biofilms - Explores the legal, social and ethical challenges of utilizing nanotechnology in clinical settings - Combines materials science concepts and techniques with clinical insights and understanding to provide an interdisciplinary approach |
| engineering precision nanoparticles for drug delivery: Nanocarrier Drug Delivery Systems Prashant L. Pingale, Sanjula Baboota, Javed Ali, 2024-08-19 Nanotechnology can treat diseases by site-specific and target-oriented delivery of precise medicines. Nanomaterials improve the efficacy of drugs and selective diagnosis. The book covers detection and treatment. It explains the use of nanocarriers for a variety of diseases such as cardiovascular and respiratory diseases, cancer, and ulcerative colitis. It includes topical, transdermal, and ocular drug delivery and combined medication delivery. |
| engineering precision nanoparticles for drug delivery: Nanotechnology Principles in Drug Targeting and Diagnosis Mahendra Rai, Shagufta Khan, Aarti Belgamwar, 2023-07-26 Nanotechnology Principles in Drug Targeting and Diagnosis focuses on the nanotechnology principles and mechanisms involved in drug targeting, nano carriers and target interactions associated with particular diseases. The book addresses how phytotherapeutics are effective against solid tumors and how they can be used in designing targeted delivery systems. Also addressed is the use of macrophages as the biomimetic carrier for targeting drugs to different organs. Sections cover the nanotechnology-based concepts in drug targeting, strategies for drug targeting, ways to identify drug carrier-target interaction, the concept of an artificial neural network in identifying drug-target interaction, and more.The book's final section concentrates on the role of nanotechnology in medical diagnosis, throwing light on nanoscale sensors for the diagnosis of viruses in the bloodstream and biomarkers indicating various cancers. This is an important reference source for materials scientists and pharmaceutical scientists who want to understand how nanotechnology plays an important role in creating more efficient drug targeting and delivery systems. - Provides extensive coverage of methods of drug-carrier-target identification and the capability of artificial intelligence to recognize patterns in patients using these patterns for nanocarrier design - Helps readers understand how nanocarriers must be functionalized for effective targeted delivery and how they can be useful tools for personalized and precise treatment of diseases - Assesses the role of nanoscale sensors in the early detection of cancer cells in the bloodstream |
| engineering precision nanoparticles for drug delivery: New Insights into Glioblastoma Carla Vitorino, Carmen Balana, Célia Cabral, 2023-05-17 New Insights into Glioblastoma: Diagnosis, Therapeutics and Theranostics provides a compendium of recent diagnostic and therapeutic advances in GBM, encompassing a pipeline of compounds and (bio) nanotechnology strategies that have stood out with potential increased antitumoral activity and capability to cross the blood-brain barrier. Issues and challenges related to their translation into the clinical practice and their contribution to the increase in survival rates and well-being of patients are addressed. This is a valuable resource for graduate students, oncologists, cancer researchers and members of the biomedical field who need to learn more on recent developments on the management of glioblastoma. The book is split in three parts: Diagnosis, focusing on biomarkers and techniques such PET/MRI, infrared thermography, and deep neural networks; Therapeutics, discussing new chemical entities, as natural products and repurposed drugs, and new formulation approaches, as nanotechnology-based and microRNA approaches; and Theranostics, explaining the role of omics, system-based approaches, and glioblastoma microenvironment. - Provides guidance towards recent advances of new chemical entities and delivery strategies targeted to glioblastoma - Includes overviews to help readers apply information in their research - Encompasses summarizing diagrams and real-world examples to facilitate comprehension and enhance the applicability of the content |
| engineering precision nanoparticles for drug delivery: ADME Processes in Pharmaceutical Sciences Alan Talevi, |
| engineering precision nanoparticles for drug delivery: Smart Nanomaterials for Bioencapsulation Guillermo R. Castro, Ashok Kumar Nadda, Swati Sharma, Ram K. Gupta, Tuan Anh Nguyen, 2022-09-30 Smart Nanomaterials for Bioencapsulation focuses on the fundamentals, synthesis methods and matrix design for the encapsulation of drugs, drug release, food and nutraceuticals, mechanisms of nano- encapsulated drugs on liposomes, micelles, silica composites, carbon nanotubes, dendrimers, and protein inorganic nanohybrids. Providing detailed information on the encapsulation of food and drug derivatives, the book helps create new and modern approaches for both pharmaceutical and nutritional science. The target delivery of pharmacological agents, as well as food additives under various conditions is covered, including sections on systemic release of drug molecules, minimum loss at non-target sites, the accumulation of diseased tissue or organs, and more. Smart nanomaterial-based nanocarriers protect the loaded molecules from premature degradation in the biological environment and enhance bioavailability for cellular uptake. The tuned properties of smart nanomaterials, such as porosity, pore-volume, surface area-to-volume ratio, coating with inert and labile materials, and more help determine the in vivo performance of the bioencapsulated food and drug derivatives. - Outlines the major design principles surrounding the encapsulation of drugs, drug release, food and nutraceuticals at the nanoscale - Discusses the pros and cons of different bioencapsulation methods for different application areas - Outlines the major challenges of applying nanobioencapsulation at an industrial scale |
| engineering precision nanoparticles for drug delivery: Nanostructured Materials for Tissue Engineering Arijit Mondal, Amit Kumar Nayak, Prithviraj Chakraborty, 2023-08-28 Nanostructured Materials for Tissue Engineering introduces the key properties and approaches involved in using nanostructured materials in tissue engineering, including functionalization, nanotechnology-based regenerative techniques, toxicological and biocompatible aspects. A broad range of nanomaterial types are covered, from polymer scaffolds and nanocomposites to gold nanoparticles and quantum dots. This book aids the reader in materials selection, as well as matching to the best applications, including bone, skin, pulmonary or neurological tissue engineering. Users will find this book to be an up-to-date review on this fast-changing field that is ideal for materials scientists, tissue engineers, biomedical engineers, and pharmaceutical scientists. - Covers the most recent advances in this fast-moving field, including all key aspects from properties and functionalization to materials selection and application in tissue engineering - Reviews a variety of nanomaterials and their benefits, including polymeric, gold and carbon nanoparticles - Explores a range of tissue engineering applications, such as cardiovascular therapies, skin repair and regeneration, and diabetes management |
| engineering precision nanoparticles for drug delivery: Nanotechnology in Societal Development Soney C. George, |
| engineering precision nanoparticles for drug delivery: Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery Prashant Kesharwani, 2023-03-02 Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therapy, are all explained in detail. The final chapters explore recent advances and regulatory aspects. This book is a valuable resource for researchers and advanced students across nanomedicine, polymer science, bio-based materials, chemistry, biomedicine, biotechnology, and materials engineering, as well as for industrial scientists and R&D professionals with an interest in nanoparticles for drug delivery, pharmaceutical formulations and regulations, and development of innovative biodegradable materials. - Presents the fundamentals of PLGA nanoparticles, including properties, preparation, characterization, and biofate and cellular interactions - Provides in-depth coverage of a broad range of specific applications of PLGA nanoparticles across disease treatment, regenerative medicine and therapeutic areas - Offers a methodical approach to PLGA nanoparticles in drug delivery that is supported by data tables, illustrative figures and flowcharts |
| engineering precision nanoparticles for drug delivery: Drug Delivery and Targeting Monika Schäfer-Korting, |
| engineering precision nanoparticles for drug delivery: Functional Materials from Lipids and Proteins Nandika Bandara, Aman Ullah, 2024-08-23 In recent years, the use of renewable raw materials and natural biopolymers has increased significantly to overcome the issues associated with environmental pollution and dwindling fossil fuel resources. Lipids and proteins are inexpensive, renewable raw materials, which are considered ideal feedstock for the development of a variety of functional materials. This book provides an international viewpoint on recent developments in the utilisation of lipids and proteins together, for the development of functional materials in food engineering, environmental and industry applications. This book presents the cutting-edge research in the utilization of lipids and proteins in food, cosmetics, therapeutics, food packaging, water remediation, biofuels, lubricants, biomaterials, and composite preparations. Researchers, scientists, engineers and students working on lipids and proteins derived materials will benefit from this book, which is highly application oriented. Focusing on the latest developments in the field, this will be the first book to describe lipids and proteins together, allowing it to act as a single reference for researchers working in this area. |
| engineering precision nanoparticles for drug delivery: Cutting-Edge Applications of Nanomaterials in Biomedical Sciences Prabhakar, Pranav Kumar, Prakash, Ajit, 2024-01-04 Cutting-Edge Applications of Nanomaterials in Biomedical Sciences is a comprehensive exploration of the revolutionary impact of nanotechnology on the field of medicine. This book delves into the remarkable potential of nanomaterials in advancing medical diagnostics and therapeutics, particularly in drug delivery. It serves as an indispensable guide, presenting the latest developments in nanomedicine, precision medicine, and nanoengineering while addressing the challenges and opportunities that arise. The book covers a wide range of topics, from nanomaterials for cancer therapy to their applications in imaging and diagnostics. It discusses the transformative role of nanomaterials in targeted delivery and controlled release, as well as their potential in regenerative medicine and infectious disease diagnosis and treatment. By presenting cutting-edge research and developments in the field, this book aims to bridge the gap between bench and bedside, providing a vital resource for researchers, clinicians, and students in the biomedical sciences. Moreover, it highlights the commercialization potential of nanomedicine, fostering collaboration between academia and industry. Policymakers and regulators will also find this book invaluable for understanding the ethical and safety implications of incorporating nanomaterials into medical practices. |
| engineering precision nanoparticles for drug delivery: Microfluidics in Pharmaceutical Sciences Dimitrios A. Lamprou, |
| engineering precision nanoparticles for drug delivery: Advanced Porous Biomaterials for Drug Delivery Applications Mahaveer Kurkuri, Dusan Losic, U.T. Uthappa, Ho-Young Jung, 2022-11-30 Advanced Porous Biomaterials for Drug Delivery Applications probes cutting-edge progress in the application of advanced porous biomaterials in drug delivery fields. These biomaterials offer promise in improving upon the design, cost, and creation of potent novel drug delivery systems. The book focuses on two categories: nature engineered and synthetic advanced porous biomaterials, with a wide range of low-cost porous biomaterial-based systems that have been used for the delivery of diverse drugs through in vitro/in vivo approaches. Details how advanced porous biomaterial-assisted systems improve essential properties in drug delivery applications Explains how advanced porous biomaterials systems are being used and explored to improve overall performances of drug delivery systems in mitigating a variety of diseases Emphasizes major applications in drug delivery such as controlled release, cancer therapy, and targeted delivery, and with focus on oral, topical, and transdermal applications Focuses on both naturally available and synthetic low-cost advanced porous biomaterials and their role in enhancing important parameters in drug delivery applications Accessible to readers with bio and non-bio backgrounds This book is an ideal reference for academics, researchers, and industry professionals in the interdisciplinary fields of biomedicine and biomedical engineering, pharmaceuticals, materials science, and chemistry. |
| engineering precision nanoparticles for drug delivery: Nanomaterials in Dental Medicine Sabu Thomas, R. M. Baiju, 2023-04-03 This book presents varied clinical applications of nanomaterials in dentistry ranging from diagnostics to therapeutics. it discusses role of nanomaterials in clinical applications and future needs. Contributors are international luminaries in their respective research area. The topics covered in this book are role of nanomaterials in oral and dental diagnosis, dental disease prevention, pain free dentistry, dental implantology. It also discusses the therapeutic applications of nanoparticles in oral cancer therapy. This book will be a valuable reference for researchers, clinicians, students and professionals working in the areas of nanotechnology and health sciences. It will also be of interest to the students and researchers primarily working in the field of materials science, applied chemistry, applied physics, and biotechnology. |
| engineering precision nanoparticles for drug delivery: Novel Platforms for Drug Delivery Applications Sangita Das, Sabu Thomas, Partha Pratim Das, 2022-11-08 Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ?-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology. - Provides an up-to-date single resource on novel drug delivery platforms, a rapidly evolving field of research - Covers a broad range of materials, systems and release mechanisms, including in vivo and in vitro studies - Describes the synthesis, properties, formulation and application of various novel drug delivery systems |
| engineering precision nanoparticles for drug delivery: Multifunctional Nanomaterials: Role and Perspectives in Combination Therapies Against Cancer Wang Zheng, Junjie Li, Jinbing Xie, 2022-06-30 |
| engineering precision nanoparticles for drug delivery: Novel Formulations and Future Trends Amit Kumar Nayak, Kalyan Kumar Sen, 2024-03-25 Novel Formulations and Future Trends, Volume Three in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics with an original approach focused on technology, novelties and future trends. It discusses the most important developments in drug delivery, including important and exciting areas such as mucosal, implantable, transdermal, gastroretentive, vaccine and targeted drug delivery systems. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students. New technologies are also explored including 3D printing and computational pharmaceutics. - Explores the most recent technologies in drug delivery in detail - Contains contributions from the leading experts from academia, research, industry and regulatory agencies - Includes high quality illustrations, flow charts and tables for easy understanding of concepts - Discusses practical examples and research case studies |
| engineering precision nanoparticles for drug delivery: Functionalized Nanomaterials for Cancer Research Hamed Barabadi, Ebrahim Mostafavi, Chaudhery Mustansar Hussain, 2024-03-22 Functionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices presents an in-depth and step by step description of knowledge on functionalized nanomaterials for cancer research, including treatment and future developments as well as their impact on patients' overall outcomes. The book discusses the functionalized nanoplatforms for cancer detection and imaging, interactions between nanomaterials and cancer cells, and drug resistant malignancies. The chapters are organized in a manner that can be readily adopted as sources for new and further studies by highlighting the main in vitro and in vivo nano-therapeutic achievements on cancer. Additionally, current trends on functionalized nanomaterials for cancer research and commercial scale opportunities are discussed. It is a valuable resource for researchers, oncologists, students, and members of the biomedical and medical fields who want to learn more about the potential of nanotechnology in cancer research and treatment. - Provides comprehensive coverage on functionalized nanomaterials for cancer therapeutics and future developments - Explores current trends on functionalized nanomaterials for cancer research and commercial scale opportunities - Discusses real-world case studies on functionalized nanomaterials for cancer therapy and research |
| engineering precision nanoparticles for drug delivery: Application of Nanocarriers in Brain Delivery of Therapeutics Amit Alexander, |
| engineering precision nanoparticles for drug delivery: Nanocarriers for Drug-Targeting Brain Tumors Lalit Kumar, Yashwant Pathak, 2022-06-21 Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. - Provides information on the design and development of nanocarriers for targeting brain tumors - Outlines the working principles of different nanocarriers for targeting brain tumors - Includes case studies of different nanocarriers for targeting brain tumors |
| engineering precision nanoparticles for drug delivery: Biomedical Applications and Toxicity of Nanomaterials P. V. Mohanan, Sudha Kappalli, 2023-05-08 This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs. |
| engineering precision nanoparticles for drug delivery: Nanomedicine Ning Gu, 2023-01-07 This handbook volume is part of the Reference Series: Micro/Nano Technologies. This individual volume provides a comprehensive, self-contained, and authoritative knowledge in nanomedicine. It covers the theoretical and practical aspects of functionalizations of nanoparticles as nanomedicine, including surface activation, characterization, and microemulsion systems. As a Springer Major Reference Work it is continuously updated online, allowing newcomers and other readers to keep in touch with the most up-to-date information. The book is particularly recommended to undergraduates, postgraduates, researchers, scientists, and field experts. It will inspire innovations in the highly interdisciplinary field of nanomedicine. |
| engineering precision nanoparticles for drug delivery: Smart Micro- and Nanomaterials for Drug Delivery Ajit Behera, Arpan Kumar Nayak, Ranjan Kumar Mohapatra, Ali Ahmed Rabaan, 2024-08-27 Smart drug delivery at both the micro- and nanoscale is an evolving field with numerous potential applications. It has the potential to revolutionize drug therapy by making treatments more effective, reducing side effects, and improving patient outcomes. This book presents a comprehensive review of the most recent studies on smart micro- and nanomaterials with a focus on their “smart” activity for formation of targeted and responsive drug-delivery carriers. This volume: Introduces readers to the fundamentals of these the micro- and nanoscale materials as well as approaches to smart drug delivery and drug delivery systems. Covers polymers, metals, and composite materials as well as quantum dots and carbon nanotubes. Describes of all possible stimulated systems for drug delivery such as enzyme-responsive, small molecules-responsive, thermo-responsive, pH-responsive, electric field-responsive, magnetic field-responsive, light-responsive, ultrasound-responsive, and reductive environment responsive. Offers a critical perspective on the future scope of smart drug delivery systems. This reference work is written to support researchers in the fields of materials engineering and biotechnology with the goal of improving the diagnosis and treatment of disease and patient quality of life. |
| engineering precision nanoparticles for drug delivery: Theranostic Applications of Nanotechnology in Neurological Disorders Akash Gautam, |
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A journal of IFAC, the International Federation of Automatic Control Artificial Intelligence (AI) is playing a major role in the fourth industrial revolution and we are seeing a lot of evolution in …
High-Entropy Approach vs. Traditional Doping Strategy for …
Jun 1, 2025 · The traditional doping strategy has emerged as an effective method for addressing challenges such as irreversible phase transitions and poor cycling s…
Food Hydrocolloids | Vol 168, December 2025 - ScienceDirect
Read the latest articles of Food Hydrocolloids at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
The effect of age on mapping auditory icons to visual icons for ...
Oct 1, 1996 · This research explored the abilities of subjects in grade 1 (6–7 years old) and grade 3 (8–9 years old) to identify …
Toward establishing a link between psychomotor task complexity and ...
Oct 1, 1996 · The objective of this research is to propose and validate a link between an existing information processing model for …
Engineering | Journal | ScienceDirect.com by Elsevier
The official journal of the Chinese Academy of Engineering and Higher Education Press. Engineering is an international open-access …
Pickering stabilization of double emulsions: Basic concepts, rationa…
Double emulsions (DEs) offer unique compartmentalized structures but are inherently unstable, prompting significant …
Engineering Structures | Journal | ScienceDirect.com by Elsevier
Engineering Structures provides a forum for a broad blend of scientific and technical papers to reflect the evolving needs of the …
