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eosinophilic esophagitis biologic therapy: Eosinophilic Gastrointestinal Diseases Glenn T. Furuta, Dan Atkins, 2009 Drs. Glen Furuta and Dan Atkins have assembled an in-depth look at Eosinophilic Gastrointestinal Diseases as related to allergy with topics such as Basic pathogenetic mechanisms of Eosinophilic Esophagitis, Nutritional management of patients with food allergies and EGIDs, Chemotactic factors role in EGIDs, Biomarkers associated with allergic diseases, Association of other allergic diseases with EGIDs and much more! |
eosinophilic esophagitis biologic therapy: The Esophagus Joel E. Richter, Donald O. Castell, David A. Katzka, Phillip O. Katz, Andre Smout, Stuart Spechler, Michael F. Vaezi, 2021-07-13 THE ESOPHAGUS The Esophagus investigates the anatomy, physiology, and pathology of the esophagus. This sixth edition, revised and updated throughout, also explores the diagnosis and treatment of various esophageal conditions. It includes treatment guidelines approved by the two largest gastroenterology societies, the ACG and AGA, as befits a work co-edited by two former presidents of those organizations. Advancements in diagnostics are presented, as are developments in the surgical and drug therapies. Presented in full colour, and boasting an unrivalled team of editors and contributing authors, The Esophagus Sixth Edition will find a home wherever the anatomy, physiology, and pathology of the esophagus are studied and taught. This book is accompanied by a website containing all the figures from the book in PowerPoint format. www.wiley.com/go/richter/esophagus6e Praise for the Fifth Edition: “There is absolutely no doubt that this edition of the textbook will maintain its status as the go-to reference for esophageal conditions, and will remain a highly utilized and clinically useful resource for novice and experienced physicians and surgeons alike.” (Gastroenterology, 1 July 2013) |
eosinophilic esophagitis biologic therapy: Subject List of Works of Reference, Biography, Bibliography, the Auxiliary Historical Sciences, Etc., in the Library of the Patent Office , 1908 |
eosinophilic esophagitis biologic therapy: Evaluation and Management of Dysphagia Dhyanesh A. Patel, Robert T. Kavitt, Michael F. Vaezi, 2019-10-23 This book provides a state-of-the-art overview of dysphagia. The text reviews current evidence behind the diagnosis, evaluation, and management of esophageal disorders that cause dysphagia, including GERD, eosinophilic esophagitis, achalasia, and spastic motor disorders. The book also focuses on the different variants of dysphagia, from oropharyngeal dysphagia to functional dysphagia, highlights advances in testing for dysphagia, and features evidence-based algorithms. Written by experts in the field, Evaluation and Management of Dysphagia: An Evidence-Based Approach is a valuable resource for gastroenterologists, otolaryngologists, and other clinicians and practitioners who treat patients afflicted with dysphagia. |
eosinophilic esophagitis biologic therapy: Textbook of Pediatric Gastroenterology, Hepatology and Nutrition Stefano Guandalini, Anil Dhawan, David Branski, 2015-09-30 This textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional problems in the various pediatric ages. The second part of the book, Hepatology, is articulated in a series of chapters which present a comprehensive review of congenital and acquired disorders of the biliary tract and liver. This section also includes a critical analysis of available diagnostic and therapeutic procedures and future perspectives. Written by experts in the field, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition: A Comprehensive Guide to Practice constitutes a much needed, innovative resource combining updated, reliable and comprehensive information with agile consultation for a streamlined approach to the care of children with such disorders. |
eosinophilic esophagitis biologic therapy: Biologic Therapies of Immunologic Diseases, An Issue of Immunology and Allergy Clinics of North America Bradley E. Chipps, Stephen P. Peters, 2017-04-12 This issue of Immunology and Allergy Clinics, guest edited by Drs. Bradley Chipps and Stephen Peters, is devoted to Biologic Therapies of Immunologic Diseases. Articles in this issue include: Immunologic Mechanisms and Potential Targets; Strategies for Immunologic Interventions; Patient Characteristics and Individualization of Therapy; Biologic Therapies for Autoimmune and Connective Tissue Diseases; Biologic Therapies for Skin Disease including Urticaria; Biologic Therapies for Asthma; Biologic Therapies for Rhinitis and Sinusitis; Biologic Therapies for Chronic Obstructive Pulmonary Disease; Biologic Therapies for Food Allergies and Eosinophilic Esophagitis; Future Prospects for Biologic Therapies of Immunologic Diseases; Pharmacoeconomics of Biologic Therapy; and Adverse Reaction to Biologic Therapy. |
eosinophilic esophagitis biologic therapy: Chronic Rhinosinusitis Wytske J. Fokkens, 2009 This issue will focus on treatments for Chronic Rhinosinusitis. Dr. Wyste Fokkens guest edits topics such as: Inflammatory mechanisms in chronic rhinosinusitis with or without nasal polyposis, European versus Asian Chronic rhinosinusitis. What did it teach us and what do we want to know, Epithelium, cilia and mucus, their importance in chronic rhinosinusitis Noam Cohen Noam, Aspirin intolerance: does desensitization alter the course of the disease, Anti-inflammatory effects of macrolides: applications in CRS, and more! |
eosinophilic esophagitis biologic therapy: Pediatric Food Allergy Ruchi S. Gupta, 2020-03-02 Comprehensive and practical, this book thoroughly addresses the full range of concerns related to food allergies in the pediatric patient. As food allergies in the pediatric population increase in number and severity, Pediatric Food Allergy: A Clinical Guide provides information on new guidelines and potential treatment options, as well as working to improve awareness, diagnosis, management and prevention practices. Written by experts in their respective fields, chapters are divided into five sections. Opening with an introduction and overview of particular concerns and issues specific to food allergy in the pediatric population, sections two and three address diagnosis and management of comorbid conditions in food allergy, along with development of food allergies and current prevention recommendations. Sections four and five cover food allergy management, prognosis, and therapeutic options with a look to future developments, while all sections include a discussion of epidemiology, differential diagnoses of other potential food-related diseases. In Pediatric Food Allergy: A Clinical Guide, pediatricians and allergists alike will find an invaluable resource as they work with this vulnerable patient population. |
eosinophilic esophagitis biologic therapy: Eosinophilic Esophagitis, An Issue of Gastrointestinal Endoscopy Clinics David A. Katzka, 2017-11-19 Eosinophilic esophagitis is an important disease that causes considerable morbidity in those afflicted. It is a major cause of esophageal symptoms, particularly dysphagia. Eosinophilic esophagitis seems to be increasing in frequency like bronchial asthma, to which it has been compared. It is complex and may have more than one pathogenesis in its varying presentations in children and adults.Dr. Katzka has invited expert authors to write clinical reviews on this complicated disease. Articles are devoted to the following topics: Pathophysiology and Definition; Incidence and Prevalence; Demographic Features; Symptoms; Endoscopic and Radiologic Findings; Children vs. Adults; Pharmacologic Treatment; Dietary Treatment; Endoscopic Treatment; and Future Directions. Readers will have the current knowledge of the endoscopic approach to diagnosis and treatment of this disease. |
eosinophilic esophagitis biologic therapy: Personalizing Asthma Management for the Clinician Stanley J. Szefler, Fernando Holguin, Michael E Wechsler, 2017-09-22 Personalized medicine is a rapidly emerging area in health care, and asthma management lends itself particularly well to this new development. This practical resource by Dr. Stanley J. Szefler helps you navigate the many asthma medication options available to your patients, as well as providing insights into those which may be introduced within the next several years. - Features a wealth of information on available asthma medications, including new immunomodulators, new responses to treatment, and new treatment strategies at all levels of asthma care. - Prepares you to meet your patients' needs regarding asthma exacerbation prevention and asthma prevention. - Consolidates today's available information and guidance in this timely area into one convenient resource. |
eosinophilic esophagitis biologic therapy: Severe Asthma in Children and Adolescents Erick Forno, Sejal Saglani, 2019-11-13 This book provides readers with a comprehensive review of severe asthma in children and adolescents, covering epidemiology, genetics, risk factors, co-morbidities, clinical presentation, diagnosis and treatment. Written by leaders in the field, chapter discussions draw on the mechanisms driving the disease, genetics, multidisciplinary approaches, immunomodulators, and other important aspects in the management of the disease. Severe Asthma in Children and Adolescents: Mechanisms and Management is designed to be a practical guide, opening with an introduction on the epidemiology of severe childhood asthma, as well as a discussion of special considerations of the disease unique to the preschool-aged patient. The distinctions between the diagnosis and management of asthma in young children of various ages, and specific approaches for the adolescent with severe asthma, including the transition into adult care are then addressed. Finally, the book closes with a discussion on the current state and future avenues for severe asthma research. Severe Asthma in Children and Adolescents is an indispensable reference for the healthcare professional, for basic and translational researchers, as well as for students, residents and fellows. |
eosinophilic esophagitis biologic therapy: Food Protein Induced Enterocolitis (FPIES) Terri Faye Brown-Whitehorn, Antonella Cianferoni, 2019-08-20 This unique book is a first-of-its-kind resource, comprehensively guiding readers through the epidemiology, pathophysiology, recent diagnostic criteria, and management options for patients with Food Protein-Induced Enterocolitis Syndrome (FPIES). Food-Protein Induced Enterocolitis Syndrome: Diagnosis and Management opens with a historical perspective of this condition, before moving into discussions of epidemiology and pathophysiology. FPIES can be difficult to diagnose as the symptoms overlap with multiple other conditions, and so clear differential diagnosis will be reviewed for both chronic FPIES, as well as acute FPIES. Later chapters are case-based, providing detailed multiple perspectives on the diagnosis and management of FPIES in patients with varying complicating factors and severity. Later chapters will tackle issues of quality of life in patient care, nutritional management for patients, and discussing working with parents and families to improve communication and at-home care. Parents, families and caregivers will also find chapters useful and relatable. A final chapter will look to the future of FPIES, addressing new research, guidelines, and implications for clinicians working with pediatric patients with FPIES, and for their families. Concise and practical, this book will be an ideal reference for allergists, pediatricians, family practice clinicians, gastroenterologists, nutritionists, and all other health care providers who encounter FPIES, and assist them in providing up-to-date, quality care for pediatric patients affected by this condition. |
eosinophilic esophagitis biologic therapy: Brain-Targeted Autoimmunity: Beyond Multiple Sclerosis Serge Nataf, Roland S. Liblau, Guillaume Dorothee, Stéphane Hunot, 2021-06-01 |
eosinophilic esophagitis biologic therapy: Finding a Path to Safety in Food Allergy National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Food and Nutrition Board, Committee on Food Allergies: Global Burden, Causes, Treatment, Prevention, and Public Policy, 2017-05-27 Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health. |
eosinophilic esophagitis biologic therapy: Eosinophilic Esophagitis Chris A. Liacouras, Jonathan E. Markowitz, 2011-10-01 This volume provides a history of Eosinophilic Esophagitis (EoE), a basic understanding of the physiology of the eosinophil, and a current understanding of the pathophysiology and genetics of EoE. The emphasis is on clinical applications including presenting symptoms, diagnosis and treatment options for patients with EoE. Written by both pediatric and adult experts in the fields of gastroenterology, allergy and pathology, this volume includes the most up to date information. Providing practical information useful in the treatment of patients, this book will be of great value to gastroenterologists, allergists, pathologists, medical residents, fellows, internists, and general practitioners who treat patients with eosinophilic esophagitis. |
eosinophilic esophagitis biologic therapy: Mayo Clinic Gastroenterology and Hepatology Board Review Stephen C. Hauser, Darrell S. Pardi, John J. Poterucha, 2003-08-27 Gastroenterology and Hepatology encompass a vast anatomic assortment of organs with diverse structure and function and the potential for affliction from a multiplicity of diseases. Completely covering these complex and interrelated systems, Mayo Clinic Gastroenterology and Hepatology Board Review provides an in-depth examination of essential knowledge in gastroenterology, hepatology, and the integral related areas of pathology, endoscopy, nutrition, and radiology. With contributions from experts at Mayo Clinic who are currently in clinical practice and have a strong commitment to teaching, the book assists physicians-in-training to prepare for the gastroenterology board examination. |
eosinophilic esophagitis biologic therapy: Human Eosinophils Gianni Marone, 2000 Eosinophils represent approximately 1% of peripheral blood leukocytes and play a central proinflammatory and immunoregulatory role in various immune disorders. This volume provides the reader with a comprehensive survey of the major aspects of human eosinophilic biology and immunology as well as the most clinically relevant aspects of eosinophil-related disorders. Expert contributions cover the ultrastructural and phenotypic characteristics of human eosinophils, and their fundamental biochemical features including receptors for IgE and chemokines. The production of cytokines and their role in the activation of eosinophils are reviewed. Furthermore, the classic eosinophil-related disorders such as hypereosinophilia, drug reactions, allergic disorders and some cardiovascular diseases are described. Each of the chapters is written by an investigator actively engaged in research on the topic under consideration. The well-edited and stimulating material compiled in this volume will be of interest to all those working in allergology, immunology, biochemistry and pulmonary medicine. |
eosinophilic esophagitis biologic therapy: Seminars in Dysphagia Renee Speyer, Hans Bogaardt, 2015-09-02 Seminars in Dysphagia provides a comprehensive overview of contemporary issues in the field of dysphagia assessment, treatment and management in diverse subject populations. Expert views are shared by international clinical experts from different medical and allied health fields. This book contains an introductory chapter on the anatomical structures and physiology processes that underpin dysphagia and discusses the effects of polypharmacy and ageing on deglutition. Contemporary practices of functional assessment of swallowing and the endoscopic assessment for both oropharyngeal and esophageal dysphagia are reviewed. Both the nutritional support and decision making in oral route are described and the impact of dysphagia on carers and family when managing dysphagia. Several chapters are dedicated to outlining the manifestation and consequences of dysphagia in specific populations, including persons with Parkinsons disease, dystonia, chronic obstructive pulmonary disease and mixed connective tissue disease. |
eosinophilic esophagitis biologic therapy: Pediatric Inflammatory Bowel Disease Petar Mamula, Jonathan E. Markowitz, Robert N. Baldassano, 2012-12-14 Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use. Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists. |
eosinophilic esophagitis biologic therapy: Adverse Reactions to Biologics L. Puig, W. Gulliver, 2017-11-07 In many areas of medicine physicians still face the great challenge of finding therapies that will meet the patients’ needs. In dermatology the challenge has arisen on multiple fronts through advances in the understanding of the immunopathogenesis of many inflammatory and malignant cutaneous disorders. Breakthroughs, combined with significant developments in targeted immunotherapy, have resulted in improved outcomes as these newer therapies are being used for both approved indications and as off-label therapies for various chronic inflammatory skin disorders and many forms of skin cancer. In the expectation that by truly understanding the safety profile of these targeted therapies patients’ outcomes will be significantly improved, this book offers insights into topics such as adverse reactions, infectious complications and the perioperative use of biologics in psoriasis, immunogenicity of biologic therapies, paradoxical reactions, safety of biologics used to treat autoimmune bullous diseases and primary cutaneous lymphomas, adverse reactions and skin manifestations of therapies targeting melanoma and non-melanoma skin cancer and other neoplastic diseases. Eminent researchers with extensive clinical experience have contributed to this publication, providing an in-depth overview of the latest knowledge in this field. |
eosinophilic esophagitis biologic therapy: Red Book Atlas of Pediatric Infectious Diseases American Academy of Pediatrics, 2007 Based on key content from Red Book: 2006 Report of the Committee on Infectious Diseases, 27th Edition, the new Red Bookr Atlas is a useful quick reference tool for the clinical diagnosis and treatment of more than 75 of the most commonly seen pediatric infectious diseases. Includes more than 500 full-color images adjacent to concise diagnostic and treatment guidelines. Essential information on each condition is presented in the precise sequence needed in the clinical setting: Clinical manifestations, Etiology, Epidemiology, Incubation period, Diagnostic tests, Treatment |
eosinophilic esophagitis biologic therapy: Severe Asthma Kian Fan Chung, Elliot Israel, Peter G. Gibson, 2019-06-01 Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma. |
eosinophilic esophagitis biologic therapy: Endoscopic Biopsy Interpretation M. Priyanthi Kumarasinghe, Ian Brown, 2018-12-10 The volume of endoscopic biopsies being performed continues to grow rapidly and they now represent one of the most common specimens encountered in routine surgical pathology practice. It is essential to maintain the balance between the speed and accuracy while integrating emerging sophisticated pathology techniques into endoscopic biopsies in routine practice. Microscopic appearance is virtually diagnostic of certain diseases. In others a diagnosis may be rendered only after correlating the microscopic pattern with clinical clues aided by ancillary tests. This text provides a guide to systematic approach of endoscopic biopsies to render a safe, quick and accurate pathological diagnosis in an integrated manner as well as important information that pathologists and clinicians should know to get the best value of endoscopic biopsies. The first chapter introduces the key microscopic features that are normal and abnormal in the gut mucosa as appreciated in an endoscopic biopsy. The second chapter presents a general overview highlighting the neoplastic and non-neoplastic patterns that are common to the entire tubular gut. Because some patterns are common to many sites, an overarching chapter gives the reader a generalized approach, which will be further refined in subsequent site specific chapters. The disease etiologies of each pattern are discussed, with emphasis placed on the most common causes that will be encountered in clinical practice. The subsequent chapters that follow then concentrate on patterns encountered at specific anatomical locations. Under each anatomical location (esophagus, stomach, small intestine and large intestine) site specific patterns of both neoplastic and non-neoplastic conditions are described. Conditions that affect many sites in the gastrointestinal tract are discussed in detail in the most relevant site chapter, but are referred to in other chapters as the reaction pattern/s they produce at that site is discussed. Ancillary tests that are required for a diagnosis of some diseases in particular neoplastic conditions are listed with tips for interpretation. This is presented mostly in a table format to assist day-to-day quick reference. In keeping with recent advances of using small biopsies for testing clinically relevant bio markers, important information that the pathologists and clinicians need to know is highlighted in appropriate sites. Authored by experts in the field, each chapter is presented under headings that include diagnostic features, patterns with relevant endoscopic and clinical clues, traps and overlapping features, and appropriate ancillary tests including clinically relevant molecular signatures in endoscopic biopsies. |
eosinophilic esophagitis biologic therapy: Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation Florence E. Roufosse, Mats W. Johansson, 2018-12-06 With the recent approval of the first eosinophil-depleting therapeutic agents targeting the IL-5 pathway for treatment of severe eosinophilic asthma, eosinophils and eosinophilic disorders are in the limelight. Indeed, setbacks during clinical development of these compounds have revealed how much remains to be known about eosinophil biology in vivo, and have nurtured profuse research both on basic eosinophil biology and on pathogenic disease mechanisms, in order to better delineate the most meaningful targets for innovative therapeutic strategies. On one hand, variable degrees of eosinophil depletion observed in some compartments during IL-5-targeted treatment indicate that certain eosinophil subsets may not rely on this cytokine and/or that other important pro-eosinophilic mediators and signaling pathways are operative in vivo. On the other hand, it is increasingly clear that disorders involving eosinophils such as asthma are the final outcome of complex interactions between diverse cell types and mediators, beyond eosinophils and IL-5. These include type 2 helper T (Th2) cells and innate lymphoid cells, mast cells, and a variety of factors that either activate eosinophils or are released by them. Although a considerable amount of research has focused on asthma because it is a common condition and because management of severe asthma remains a major challenge, several rare eosinophilic disorders with more homogenous features have proven to be extremely useful models to reach a better understanding of the involvement of eosinophils in tissue damage and dysfunction, and of the micro-environmental interactions operating within the complex network of eosinophilic inflammation. Unraveling this interplay has resulted in advances in the development of molecular tools to detect disease subsets and to monitor therapeutic responses, and in identification of promising new therapeutic targets. This Research Topic dedicated to eosinophilic conditions covers aspects of the biology of eosinophils and closely related cells of particular relevance for drug development, reports on translational research investigating pathogenic mechanisms of specific eosinophilic disorders in humans that will likely result in significant changes in the way patients are managed, and presents an overview of the current advancement of targeted drug development for these conditions, with a special focus on asthma. |
eosinophilic esophagitis biologic therapy: Eosinophils in Health and Disease James J. Lee, Helene F. Rosenberg, 2012-11-02 Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance. |
eosinophilic esophagitis biologic therapy: Practical Gastrointestinal Pathology Hanlin L. Wang, Zongming Eric Chen, 2020-12-05 This book addresses practical issues that reflect the current landscape of GI pathology practice and is organized in such a way that fits the fast-pacing daily life of practicing pathologists. It contains more than 540 questions that address difficult, prevailing and controversial issues in GI pathology that are frequently encountered in daily practice and consult service. For most questions, answers are straightforward with ample literature support. However, true diagnostic controversies and clinical dilemma cannot be easily resolved with current knowledge and available information. To such challenges, an expert approach regarding how to synthesize complicated topics and clearly communicate the thinking process is valuable to readers and can help guide clinicians making optimal treatment plans for their patients. The latter types of answers are highly enriched throughout the book. Distinct from other existing GI pathology textbooks, this book is primarily organized according to disease entities and pathological processes instead of specific organs and anatomic locations. Guided by chapter titles and listed questions, readers should be able to look up a disease or a pathological feature and find the most important and relevant diagnostic criteria and pertinent differential diagnoses. Written by experts in the field, Practical Gastrointestinal Pathology provides easy and quick access to concise, evidence-based and up-to-date information to aid accurate diagnosis and serves as a useful resource for practicing pathologists, pathology trainees and GI clinicians as well as allied health professionals who frequently deal with GI pathology. |
eosinophilic esophagitis biologic therapy: Symptom-Based Diagnosis in Pediatrics (CHOP Morning Report) Samir S. Shah, Stephen Ludwig, 2014-01-03 A CASE-BASED GUIDE TO PEDIATRIC DIAGNOSIS, CONVENIENTLY ORGANIZED BY PRESENTING SYMPTOMS Symptom-Based Diagnosis in Pediatrics features 19 chapters, each devoted to a common pediatric complaint. Within each chapter, five to eight case presentations teach the diagnostic approach to the symptom. The case presentations follow a consistent outline of History, Physical Examination, and Course of Illness, and are followed by discussion of the Differential Diagnosis, Diagnosis Incidence and Epidemiology, Clinical Manifestations, Diagnostic Approach, and Treatment. Cases are illustrated with vibrant full-color photographs and include numerous tables comparing potential diagnoses. Organized by symptoms--the way patients actually present More than 100 cases teach the diagnostic approach to a symptom Cases illustrate how the same complaint can have a variety of causes Full-color clinical photos and illustrations sharpen your visual diagnosis skills Valuable tables detail the most frequent causes of common symptoms CASE-BASED COVERAGE OF THE SYMPTOMS YOU'RE MOST LIKELY TO ENCOUNTER IN PEDIATRIC PRACTICE Wheezing * Decreased Activity Level * Vomiting * Coughing * Back, Joint, and Extremity Pain * Poor Weight Gain * Abdominal Pain * Altered Mental Status * Rash * Pallor * Fever * Constipation * Neck Swelling * Chest Pain * Jaundice * Abnormal Gait * Diarrhea * Syncope * Seizures Editors Samir S. Shah, MD, MSCE is Director, Division of Hospital Medicine, James M. Ewell Endowed Chair, and Attending Physician in Hospital Medicine & Infectious Diseases at Cincinnati Children’s Hospital Medical Center; and Professor in the Department of Pediatrics at the University of Cincinnati College of Medicine. Stephen Ludwig, MD is Chairman of the Graduate Medical Education Committee and Continuing Medical Education Committee and an attending physician in general pediatrics at The Children's Hospital of Philadelphia; and Emeritus Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania. |
eosinophilic esophagitis biologic therapy: Childhood Asthma Stanley J Szefler, Soren Pedersen, 2005-09-26 This reference collects the latest studies on the development, diagnosis, and treatment of childhood asthma and offers current perspectives on new technologies that will shape the management of pediatric asthma in the forthcoming decade-illustrating how advances in pulmonary function measurement, inflammatory markers, imaging, and pharmacogenetics |
eosinophilic esophagitis biologic therapy: Immune Rebalancing Diana Boraschi, Giselle Penton-Rol, 2016-01-25 Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine. Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc. - Visits immunosuppression from a modern point of view of signalling mechanisms at the light of the current knowledge of signalling mechanisms and regulatory networks allows the reader to formulate new ideas and concepts on how to use immunosuppression the therapeutic purposes - Encourages researchers to engage into exploring the field of pharmacological modulation of immune responses in depth, and with the new knowledge and tools available, designs more effective therapeutic strategies to autoimmune and inflammatory diseases, cancer, degenerative diseases and infections - Examines the link between molecular pathways associated to immune-suppression and the new immunopharmacology approaches - Provides information on the new strategies for drug development in this field - Considers the role of microbes in the development of the mammalian immune system and immune responses, which will widen the reader's strategy for addressing therapeutic immune modulations |
eosinophilic esophagitis biologic therapy: Eosinophilic Gastrointestinal Diseases, An Issue of Immunology and Allergy Clinics of North America, E-Book Glenn T. Furuta, Dan Atkins, 2024-04-05 In this issue of Immunology and Allergy Clinics, guest editors Drs. Glenn T. Furuta and Dan Atkins bring their considerable expertise to the topic of Eosinophilic Gastrointestinal Diseases. Top experts provide a multilayered examination of the current state of knowledge in the field, compiling an issue that serves as a convenient reference for the evaluation and management of eosinophilic esophagitis (EoE) and eosinophilic gastrointestinal diseases (EGIDs). - Contains 21 relevant, practice-oriented topics including epidemiological and clinical clues to the etiology of EoE; dietary management of EoE; quality of life with EoE; diversity, equity, and inclusion in EoE; clinical presentation of patients with EGIDs; pharmacologic management of EGIDs; and more. - Provides in-depth clinical reviews on eosinophilic gastrointestinal diseases, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. |
eosinophilic esophagitis biologic therapy: NORD Guide to Rare Disorders National Organization for Rare Disorders, 2003 NORD Guide to Rare Disorders is a comprehensive, practical, authoritative guide to the diagnosis and management of more than 800 rare diseases. The diseases are discussed in a uniform, easy-to-follow format--a brief description, signs and symptoms, etiology, related disorders, epidemiology, standard treatment, investigational treatment, resources, and references.The book includes a complete directory of orphan drugs, a full-color atlas of visual diagnostic signs, and a Master Resource List of support groups and helpful organizations. An index of symptoms and key words offers physicians valuable assistance in finding the information they need quickly. |
eosinophilic esophagitis biologic therapy: Pathology of the Gastrointestinal Tract Fátima Carneiro, Paula Chaves, Arzu Ensari, 2017-06-28 This book covers the complete field of the pathology of the Gastrointestinal tract - from Abetalipoproteinemia to Zollinger-Ellison Syndrome. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need. |
eosinophilic esophagitis biologic therapy: Biologics in Allergic/Immunologic Conditions, An Issue of Immunology and Allergy Clinics of North America Flavia Hoyte, 2024-10-14 In this issue of Immunology and Allergy Clinics, guest editor Dr. Flavia Hoyte brings her considerable expertise to the topic of Biologics in Allergic/Immunologic Conditions. Top experts provide an overview of the state of biologic treatments for autoimmune and allergic conditions including asthma, COPD, food allergies, atopic dermatitis; and more. - Contains 13 relevant, practice-oriented topics including current and emerging biologics in CSU; biologics in AERD and ABPA; and multiple articles on biologics in asthma, including the role of biomarkers, the potential to achieve clinical remission, real-world studies, emerging biologics; and more. - Provides in-depth clinical reviews on biologics in allergic/immunologic conditions, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. |
eosinophilic esophagitis biologic therapy: Nijkamp and Parnham's Principles of Immunopharmacology Michael J. Parnham, Frans P. Nijkamp, Adriano G. Rossi, 2019-12-10 Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system. |
eosinophilic esophagitis biologic therapy: Cutaneous T-Cell Lymphoma Herschel S. Zackheim, 2004-10-28 Cutaneous T-cell lymphoma (CTCL) is a general term for many lymphomas of the skin including mycosis Fungoides and Sezary syndrome. This book presents the state of the art in CTCL epidemiology, clinical features, pathology, immunochemistry, diagnostic molecular techniques, staging and prognosis, and treatment. Edited by one of the leading experts in |
eosinophilic esophagitis biologic therapy: Biologics for the Treatment of Allergic Diseases, An Issue of Immunology and Allergy Clinics of North America, E-Book Lanny J. Rosenwasser, 2020-10-15 This issue of Immunology and Allergy Clinics, guest edited by Dr. Lanny Rosenwasser, will provide up-to-date clinical concepts regarding Biologics for the Treatments of Allergic Conditions. Articles in this outstanding issue include: Allergic Rhinitis/CRS/Polyposis, Eosinophilic Asthma, Pediatric Asthma, Severe Asthma, ACOS/COPD, Food Allergy, Atopic Dermatitis, Chronic Urticaria, Anaphylaxis, Drug Allergy, Cell Disorders, Biologics and Immunotherapy, and much more. |
eosinophilic esophagitis biologic therapy: Adhesion Molecules in Allergic Disease Bruce S. Bochner, 2020-08-18 This unique resource-the first book of its kind exclusively devoted to the subject-offers timely coverage of the cells, mechanisms, and proteins involved in allergic inflammation, emphasizing the latest advances in local cell recruitment. |
eosinophilic esophagitis biologic therapy: Pediatric Gastroenterology E-Book Chris A. Liacouras, David A. Piccoli, 2007-11-22 This volume in the Requisites in Pediatrics series offers expert guidance in the assessment and treatment of gastroenterological disorders commonly encountered in clinical practice. It delivers all the information you need in the proven high-yield Requisites format - equipping you to master the material quickly. Perfect for quick review and exam preparation, this is one resource you'll consult over and over again! Follows a logical, consistent chapter format to facilitate quick and easy reference. Offers abundant tables that present differential diagnoses, lab values / radiologic studies, treatment / therapy recommendations, and guidance on when to refer to a specialist. Presents thought-provoking clinical scenarios to help you determine the best course of action in situations where there are controversies concerning the standard of care. Features a wealth of illustrations that make details clearer. Includes highlighted boxes that emphasize relevant case studies · key points of each section · current controversies · and other important information. |
eosinophilic esophagitis biologic therapy: Patterson's Allergic Diseases Leslie Carroll Grammer, Paul A. Greenberger, 2009 Revised and updated, this highly acclaimed volume is a complete, current, and practical guide to the diagnosis and treatment of allergic disorders. This comprehensive yet concise reference will remain the first choice for residents and practitioners who need guidance to identify an allergy, confirm a diagnosis, or find effective therapies. |
eosinophilic esophagitis biologic therapy: CURRENT Essentials of Medicine, Fourth Edition Lawrence M. Tierney, Sanjay Saint, Mary A. Whooley, 2010-11-12 The perfect quick reference on the wards and in the clinic! The famous one disease per page design! CURRENT Essentials of Medicine is a practical, point-of-care pocket handbook that offers nutshell information on the diagnosis and treatment of more than 500 medical disorders seen in both primary care and hospital settings. Perfect as a quick reference on the wards or in a busy clinic, this is THE ONLY pocket guide to offer disease essentials in a one-disease-per-page bulleted format. Practical pearls, for which the authors are well known, are offered for almost all conditions. Features To-the-point information on the diagnosis and treatment of more than 500 of the most common diseases seen in clinical practice Convenient one-disease-per page presentation Bulleted data for each disease covering Essentials of Diagnosis, Differential Diagnosis, Treatment, Pearl, and Reference Encompasses both ambulatory and inpatient medicine Includes internal medicine, plus specialties such as obstetrics/gynecology, surgery, and pediatrics Updated clinical manifestations, diagnostic tests, and treatment considerations throughout |
Eosinophilia Causes - Mayo Clinic
Eosinophilia happens when eosinophils swarm a site in the body. Or when the bone marrow makes too many. This can happen due to many reasons including: Parasitic and fungal …
Eosinophilic esophagitis - Symptoms and causes - Mayo Clinic
Jul 2, 2024 · Eosinophilic esophagitis (e-o-sin-o-FILL-ik uh-sof-uh-JIE-tis) is a chronic immune system disease. With this disease, a type of white blood cell, called an eosinophil, builds up in …
Eosinophilia - Mayo Clinic
Eosinophilia (e-o-sin-o-FILL-e-uh) is the presence of too many eosinophils in the body. An eosinophil is part of a group of cells called white blood cells. They are measured as part of a …
Eosinophilic esophagitis care at Mayo Clinic
Jul 2, 2024 · Eosinophilic esophagitis care at Mayo Clinic Your Mayo Clinic care team At Mayo Clinic's campus in Rochester, Minnesota, doctors from a wide variety of departments, …
Hypereosinophilic syndrome - Symptoms and causes - Mayo Clinic
Apr 27, 2022 · Hypereosinophilic syndrome is a disorder of certain types of white blood cells that can cause life-threatening damage to your organs.
Churg-Strauss syndrome - Symptoms & causes - Mayo Clinic
Feb 7, 2024 · Churg-Strauss syndrome is a disorder marked by blood vessel inflammation. This inflammation can restrict blood flow to organs and tissues, sometimes permanently damaging …
Hypereosinophilic syndrome - Diagnosis and treatment - Mayo Clinic
Apr 27, 2022 · Diagnosis Many types of disorders can raise your eosinophil level, including certain infections, allergies and reactions to medications. When trying to determine whether you have …
Eosinophilic esophagitis - Diagnosis and treatment - Mayo Clinic
Jul 2, 2024 · Learn more about the causes and treatment of eosinophilic esophagitis — a digestive disease caused by an allergic reaction.
Eosinophilia When to see a doctor - Mayo Clinic
It's important to know what other health conditions you may have. Eosinophilia will likely resolve with the right diagnosis and treatment. If you have hypereosinophilic syndrome, your care …
Esofagitis eosinofílica - Síntomas y causas - Mayo Clinic
Nov 7, 2024 · Obtén más información sobre las causas y el tratamiento de la esofagitis eosinofílica, una enfermedad digestiva causada por una reacción alérgica.
Eosinophilia Causes - Mayo Clinic
Eosinophilia happens when eosinophils swarm a site in the body. Or when the bone marrow makes too many. This can happen due to many reasons including: Parasitic and fungal diseases Allergic …
Eosinophilic esophagitis - Symptoms and causes - Mayo Clinic
Jul 2, 2024 · Eosinophilic esophagitis (e-o-sin-o-FILL-ik uh-sof-uh-JIE-tis) is a chronic immune system disease. With this disease, a type of white blood cell, called an eosinophil, builds up in the …
Eosinophilia - Mayo Clinic
Eosinophilia (e-o-sin-o-FILL-e-uh) is the presence of too many eosinophils in the body. An eosinophil is part of a group of cells called white blood cells. They are measured as part of a …
Eosinophilic esophagitis care at Mayo Clinic
Jul 2, 2024 · Eosinophilic esophagitis care at Mayo Clinic Your Mayo Clinic care team At Mayo Clinic's campus in Rochester, Minnesota, doctors from a wide variety of departments, including …
Hypereosinophilic syndrome - Symptoms and causes - Mayo Clinic
Apr 27, 2022 · Hypereosinophilic syndrome is a disorder of certain types of white blood cells that can cause life-threatening damage to your organs.
Churg-Strauss syndrome - Symptoms & causes - Mayo Clinic
Feb 7, 2024 · Churg-Strauss syndrome is a disorder marked by blood vessel inflammation. This inflammation can restrict blood flow to organs and tissues, sometimes permanently damaging …
Hypereosinophilic syndrome - Diagnosis and treatment - Mayo Clinic
Apr 27, 2022 · Diagnosis Many types of disorders can raise your eosinophil level, including certain infections, allergies and reactions to medications. When trying to determine whether you have …
Eosinophilic esophagitis - Diagnosis and treatment - Mayo Clinic
Jul 2, 2024 · Learn more about the causes and treatment of eosinophilic esophagitis — a digestive disease caused by an allergic reaction.
Eosinophilia When to see a doctor - Mayo Clinic
It's important to know what other health conditions you may have. Eosinophilia will likely resolve with the right diagnosis and treatment. If you have hypereosinophilic syndrome, your care team …
Esofagitis eosinofílica - Síntomas y causas - Mayo Clinic
Nov 7, 2024 · Obtén más información sobre las causas y el tratamiento de la esofagitis eosinofílica, una enfermedad digestiva causada por una reacción alérgica.