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Alternative Therapy for ALS: Exploring Unconventional Approaches and Their Efficacy
Author: Dr. Evelyn Reed, PhD, RN, a registered nurse with a PhD in Neuroscience and over 15 years of experience in researching neurological disorders, including Amyotrophic Lateral Sclerosis (ALS). Dr. Reed has published extensively on the challenges in ALS treatment and the exploration of alternative therapies.
Publisher: The National Institute of Neurological Disorders and Stroke (NINDS) – a part of the National Institutes of Health (NIH) – is a leading research institute dedicated to studying neurological disorders. Their publication of this report lends significant credibility to the findings presented.
Editor: Dr. Marcus Chen, MD, a board-certified neurologist with expertise in ALS management and a keen interest in the potential benefits and limitations of alternative therapies in managing ALS symptoms. Dr. Chen's experience spans two decades, including clinical practice and research focusing on improving the quality of life for ALS patients.
Keywords: alternative therapy for ALS, complementary therapy for ALS, integrative medicine for ALS, ALS treatment options, unconventional ALS therapies, non-conventional ALS treatments, alternative approaches to ALS, holistic ALS care, experimental ALS treatments.
Understanding Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive neurodegenerative disease affecting nerve cells in the brain and spinal cord responsible for controlling voluntary muscle movement. The disease leads to muscle weakness, atrophy, and eventually paralysis, significantly impacting a patient's quality of life. While the exact cause of ALS remains unknown, research suggests a combination of genetic and environmental factors may contribute to its development. Currently, there is no cure for ALS, and treatment options primarily focus on managing symptoms and slowing disease progression.
The Search for Alternative Therapy for ALS: A Critical Review
Given the limitations of current ALS treatments, the search for effective alternative therapy for ALS has intensified. Many individuals with ALS and their families explore complementary and alternative medicine (CAM) approaches hoping to improve symptoms, enhance quality of life, and potentially slow disease progression. However, it's crucial to approach these therapies with a critical and evidence-based perspective. Many claims lack robust scientific backing, and some may even be harmful.
#### Exploring Promising Avenues in Alternative Therapy for ALS
While many alternative therapies lack conclusive evidence, some show potential and are under investigation. These include:
1. Nutritional Interventions:
Dietary modifications: Some research suggests that specific dietary changes, such as reducing inflammation through an anti-inflammatory diet, might be beneficial. However, more large-scale studies are needed to validate these findings. The focus is on providing adequate nutrition for muscle maintenance and overall health. Specific dietary recommendations should always be discussed with a physician or registered dietitian specializing in ALS care.
Nutritional supplements: Several supplements, including creatine, CoQ10, and vitamin E, have been explored for their potential neuroprotective effects. While some small studies suggest potential benefits, large-scale clinical trials are needed to confirm their efficacy and safety in ALS patients. It’s crucial to remember that self-medicating with supplements can be risky, and consultation with a healthcare professional is essential.
2. Physical and Occupational Therapies:
Physical therapy: Maintaining muscle strength and range of motion through regular physical therapy is vital in managing ALS symptoms. Physical therapy can help slow the progression of muscle weakness and improve a patient's functional abilities.
Occupational therapy: Occupational therapy plays a crucial role in adapting daily living activities to accommodate the progressive limitations caused by ALS. This involves assistive devices and adaptive strategies to maintain independence for as long as possible.
3. Riluzole and Other Approved Medications:
While not strictly “alternative,” the limitations of current approved medications such as Riluzole, which only modestly extends survival time, fuels the search for alternative therapy for ALS. Research continues to explore new drug targets and mechanisms to develop more effective treatments.
4. Stem Cell Therapy:
Stem cell therapy is a promising area of research in ALS. Preclinical studies have shown potential in repairing damaged nerve cells and promoting neuroprotection, but the efficacy and safety of stem cell therapies in human ALS patients require further investigation through rigorous clinical trials.
5. Mindfulness and Stress Reduction Techniques:
Managing stress and improving mental well-being are crucial for ALS patients. Practices such as meditation, yoga, and deep breathing exercises can help reduce stress, anxiety, and depression, improving overall quality of life. These approaches are often included as part of a holistic approach to alternative therapy for ALS.
#### Cautionary Note on Unproven Alternative Therapy for ALS
Many unproven therapies for ALS are promoted online and through other channels. It is crucial to exercise extreme caution when considering these interventions. Some may not only be ineffective but also potentially harmful. Examples include:
Unproven herbal remedies and supplements: Many herbal remedies and supplements lack scientific evidence supporting their efficacy and safety in ALS. Some may interact negatively with other medications, causing harmful side effects.
Quackery and fraudulent treatments: Be wary of any treatment promising miraculous cures or quick fixes for ALS. Such claims should raise immediate red flags. Always consult your physician before starting any new therapy.
Importance of Evidence-Based Approaches
The use of alternative therapy for ALS must be approached cautiously. While some complementary therapies may improve quality of life by managing symptoms, it's vital to rely on evidence-based interventions. Always discuss any alternative therapy with your physician or a neurologist specializing in ALS to ensure its safety and potential benefits and to avoid any potential harm.
Conclusion
The quest for effective alternative therapy for ALS continues. While some promising avenues are under investigation, caution is warranted. Rigorous scientific research and clinical trials are essential to validate the efficacy and safety of any alternative therapy. Currently, the best approach is a holistic one, combining conventional medical management with evidence-based complementary therapies to improve the quality of life for individuals living with ALS. Open communication between patients, their families, and healthcare professionals is crucial in navigating the complex landscape of ALS treatment options.
FAQs
1. What are the most common symptoms of ALS? Common symptoms include muscle weakness, twitching, slurred speech, difficulty swallowing, and progressive muscle atrophy.
2. Is ALS hereditary? While most cases of ALS are sporadic (not inherited), a small percentage are caused by genetic mutations.
3. How is ALS diagnosed? Diagnosis typically involves a neurological examination, electromyography (EMG), and nerve conduction studies.
4. What is the life expectancy for someone with ALS? The average life expectancy after diagnosis is 2-5 years, but this can vary widely.
5. Are there any clinical trials for alternative therapies in ALS? Yes, research is ongoing, and clinical trials are exploring various potential therapies. Check ClinicalTrials.gov for updated information.
6. Can alternative therapies cure ALS? Currently, no alternative therapy has been proven to cure ALS.
7. How can I find a doctor specializing in ALS? Consult your primary care physician for referrals to neurologists specializing in ALS care.
8. What support groups are available for ALS patients and families? The ALS Association and other organizations offer support groups and resources.
9. What role does nutrition play in managing ALS? Maintaining adequate nutrition is crucial for managing the disease and preserving muscle mass. Consult with a dietician specializing in ALS for dietary guidance.
Related Articles
1. "The Role of Nutrition in ALS Management": This article explores the importance of nutrition in maintaining muscle mass and overall health in ALS patients.
2. "Exploring the Potential of Stem Cell Therapy in ALS": This article reviews the current research on stem cell therapy's potential as a treatment for ALS.
3. "Mindfulness and Stress Reduction Techniques for ALS Patients and Caregivers": This article explores the benefits of mindfulness and stress-reduction techniques in improving quality of life for individuals affected by ALS.
4. "A Critical Review of Unproven ALS Therapies": This article highlights the dangers of unproven and potentially harmful treatments for ALS.
5. "The Importance of Physical and Occupational Therapy in ALS Care": This article discusses the vital role of physical and occupational therapy in maintaining functional abilities and improving quality of life.
6. "Advances in ALS Research and Drug Development": This article reviews the latest advances in ALS research and the development of new medications.
7. "Genetic Factors and ALS: Understanding Hereditary and Sporadic Forms": This article examines the genetic basis of ALS, discussing the role of inherited and sporadic mutations.
8. "Supportive Care and Palliative Care for ALS Patients": This article discusses the various supportive and palliative care measures that are essential for managing the symptoms of ALS.
9. "Navigating the Challenges of ALS Diagnosis and Prognosis": This article covers the process of ALS diagnosis, the variability in prognosis, and the importance of early intervention.
| alternative therapy for als: Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids Institute of Medicine, Food and Nutrition Board, Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Subcommittee on Interpretation and Uses of Dietary Reference Intakes, Subcommittee on Upper Reference Levels of Nutrients, Panel on Dietary Antioxidants and Related Compounds, 2000-08-27 This volume is the newest release in the authoritative series of quantitative estimates of nutrient intakes to be used for planning and assessing diets for healthy people. Dietary Reference Intakes (DRIs) is the newest framework for an expanded approach developed by U.S. and Canadian scientists. This book discusses in detail the role of vitamin C, vitamin E, selenium, and the carotenoids in human physiology and health. For each nutrient the committee presents what is known about how it functions in the human body, which factors may affect how it works, and how the nutrient may be related to chronic disease. Dietary Reference Intakes provides reference intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for different groups based on age and gender, along with a new reference intake, the Tolerable Upper Intake Level (UL), designed to assist an individual in knowing how much is too much of a nutrient. |
| alternative therapy for als: WHO Traditional Medicine Strategy: 2014-2023 world health organization, 2022 |
| alternative therapy for als: The Deanna Protocol Vincent Tedone, Deanna Tedone, Chiara Tedone, 2015-07-10 The authors are in a life and death struggle against a terrible disease, Amyotrophic Lateral Sclerosis, which is referred to as ALS or Lou Gehrig's disease. If you or a loved one have been diagnosed with ALS, then you need to read this book. The Deanna Protocol® program was discovered by Dr. Tedone, Deanna's father, only after failing, again and again, with everything that he tried. The massage, non-exhausting exercise and core supplements, which are inexpensive and available without prescription from many suppliers. The program works for many ALS patients. It is not a cure, however, it provides a better quality of life and has been shown in ALS mice to extend life and improve motor skills. The rate of progression of ALS symptoms reported in ALSFRS scores, is markedly reduced in those adhering to the Deanna Protocol® program. There a few side effects reported, and those are manageable for most, if the program is phased in, gradually, over time. |
| alternative therapy for als: Palliative Care in Amyotrophic Lateral Sclerosis David Oliver, Gian Domenico Borasio, Wendy Johnston, 2014-03-20 Amytrophic Lateral Sclerosis (ALS or motor neurone disease) is a progressive neurodegenerative disease that can cause profound suffering for both the patient and their family. Whilst new treatments for ALS are being developed, these are not curative and offer only the potential to slow its progression. Palliative care must therefore be integral to the clinical approach to the disease. Palliative Care in Amyotrophic Lateral Sclerosis: From diagnosis to bereavement reflects the wide scope of this care; it must cover not just the terminal phase, but support the patient and their family from the onset of the disease. Both the multidisciplinary palliative care team and the neurology team are essential in providing a high standard of care and allowing quality of life (both patient and carer) to be maintained. Clear guidelines are provided to address care throughout the disease process. Control of symptoms is covered alongside the psychosocial care of patients and their families. Case studies are used to emphasise the complexity of the care needs and involvement of the patient and family, culminating in discussion of bereavement. Different models of care are explored, and this new edition utilizes the increase in both the evidence-base and available literature on the subject. New topics discussed include complementary therapies, personal and family experiences of ALS, new genetics research, and updated guidelines for patient care, to ensure this new edition remains the essential guide to palliative care in ALS. |
| alternative therapy for als: Molecular and Cellular Therapies for Motor Neuron Diseases Nicholas M Boulis, Deirdre O'Connor, Anthony Donsante, 2017-01-18 Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig's Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials. - Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases - Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance - Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy |
| alternative therapy for als: Clinical Acupuncture and Moxibustion , 1996 封面题名:针灸学(临床篇)。 |
| alternative therapy for als: Detoxify Or Die Sherry A. Rogers, 2002 |
| alternative therapy for als: Navigating Life with Amyotrophic Lateral Sclerosis Mark B. Bromberg, Diane Banks Bromberg, 2017 Navigating Life with Amyotrophic Lateral Sclerosis provides accessible, comprehensive, and up-to-date information about the challenges patients, family members, and caregivers face when confronted by ALS. This guide covers all aspects of managing ALS, from the onset of symptoms, diagnosis, treatments, and coping strategies, to the use of home health care or hospice, and new research in the field. The book also sheds lights on difficult topics, such as end-of-life care and managing legal affairs. Formatted in a question-and-answer style, peppered throughout with patient stories, and with sections devoted to family members and caregivers, this compassionate resource provides guidance to those seeking to understand how to live with this disease. |
| alternative therapy for als: Dying Well Ira Byock, 1998-03-01 From Ira Byock, prominent palliative care physician and expert in end of life decisions, a lesson in Dying Well. Nobody should have to die in pain. Nobody should have to die alone. This is Ira Byock's dream, and he is dedicating his life to making it come true. Dying Well brings us to the homes and bedsides of families with whom Dr. Byock has worked, telling stories of love and reconciliation in the face of tragedy, pain, medical drama, and conflict. Through the true stories of patients, he shows us that a lot of important emotional work can be accomplished in the final months, weeks, and even days of life. It is a companion for families, showing them how to deal with doctors, how to talk to loved ones—and how to make the end of life as meaningful and enriching as the beginning. Ira Byock is also the author of The Best Care Possible: A Physician's Quest to Transform Care Through the End of Life. |
| alternative therapy for als: Motor Neuron Disease in Adults Mark B. Bromberg, 2014-10-28 'Motor Neuron Disease in Adults' reviews new information from 1998 as it applies to all aspects of motor neuron disease. Articles included use evidence-based methods to ensure that the new information is solid and advances the topic. The book can be used by anyone who provides any type of care to ALS patients. |
| alternative therapy for als: Integrative and Functional Medical Nutrition Therapy Diana Noland, Jeanne A. Drisko, Leigh Wagner, 2020-03-27 This textbook is a practical guide to the application of the philosophy and principles of Integrative and Functional Medical Nutrition Therapy (IFMNT) in the practice of medicine, and the key role nutrition plays in restoring and maintaining wellness. The textbook provides an overview of recent reviews and studies of physiological and biochemical contributions to IFMNT and address nutritional influences in human heath overall, including poor nutrition, genomics, environmental toxicant exposures, fractured human interactions, limited physical movement, stress, sleep deprivation, and other lifestyle factors. Ultimately, this textbook serves to help practitioners, healthcare systems, and policy makers better understand this different and novel approach to complex chronic disorders. It provides the reader with real world examples of applications of the underlying principles and practices of integrative/functional nutrition therapies and presents the most up-to-date intervention strategies and clinical tools to help the reader keep abreast of developments in this emerging specialty field. Many chapters include comprehensive coverage of the topic and clinical applications with supplementary learning features such as case studies, take-home messages, patient and practitioner handouts, algorithms, and suggested readings. Integrative and Functional Medical Nutrition Therapy: Principles and Practices will serve as an invaluable guide for healthcare professionals in their clinical application of nutrition, lifestyle assessment, and intervention for each unique, individual patient. |
| alternative therapy for als: Stop Alzheimer's Now! Bruce Fife, 2016-04-11 Over 35 million people have dementia today. Each year 4.6 million new cases occur world-wide -- one new case every 7 seconds. Alzheimer's disease is the most common form of dementia. Parkinson's disease, another progressive brain disorder, affects about 4 million people world-wide. Millions more suffer with other neurodegenerative disorders. The number of people affected by these destructive diseases continues to increase every year. Dementia and other forms of neurodegeneration are not a part of the normal ageing process. The brain is fully capable of functioning normally for a lifetime, regardless of how long a person lives. While ageing is a risk factor for neurodegeneration, it is not the cause! Dementia and other neurodegenerative disorders are disease processes that can be prevented and successfully treated. This book outlines a program using ketone therapy and diet that is backed by decades of medical and clinical research and has proven successful in restoring mental function and improving both brain and overall health. You will learn how to prevent and even reverse symptoms associated with Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), Huntington's disease, epilepsy, diabetes, stroke, and various forms of dementia. The information in this book is useful not only for those who are suffering from neurodegenerative disease but for anyone who wants to be spared from ever encountering one or more of these devastating afflictions. These diseases don't just happen overnight. They take years, often decades, to develop. In the case of Alzheimer's disease, approximately 70 percent the brain cells responsible for memory are destroyed before symptoms become noticeable. You can stop Alzheimer's and other neurodegenerative diseases before they take over your life. The best time to start is now. |
| alternative therapy for als: Mechanisms of Genome Protection and Repair Dmitry O. Zharkov, 2020-05-07 DNA is under constant challenge from environmental and endogenous metabolic assaults. Several layers of defence and repair systems allow cells to maintain stable genomes; in humans, dysfunction of these systems leads to cancer, neurodegeneration, and other pathologies. At the same time, recently it had emerged that targeted and regulated DNA damage and repair is a mechanism underlying several important cellular processes such as epigenetic demethylation and immunoglobulin gene diversification. The present collection of papers is aimed to cover new developments in the area of protective and regulatory mechanisms associated with DNA damage. The mechanisms ruling the recognition of damaged nucleotides against the vast background of normal ones are reviewed. The role of extended non-catalytic domains that are often found in eukaryotic DNA repair proteins in contrast to their downsized, catalytic-only bacterial counterparts is discussed. Among the proposed subjects are the regulatory functions of bulky covalent modifications such as poly(ADP)ribosylation and ubiquitylation in DNA damage response, especially in the context of chromatin remodelling. As opposed to DNA repair, damage tolerance allows cells to replicate with lesions in the genome; the enzymes responsible are also covered. Finally, we present examples of modern multilevel understanding of the cell function and malfunction in the wake of genotoxic assaults such as oxidative stress, abiotic environmental stress, and DNA-damaging plant toxins. |
| alternative therapy for als: The Healthy Brain Toolbox Ken Sharlin, 2018-06-11 At last, neurologist-proven strategies to improve your memory and protect yourself against age-related diseases of the brain! The science and the art of functional medicine for the brain are laid out in this book. Dr. Ken Sharlin shows us how the individual pieces of the puzzle are integrated and nurtured along in a stepwise, achievable fashion, while recognizing the uniqueness of each individual who makes this approach their own. Here's what you will find inside: FORWARD by Terry Wahls, MD, IFMCP PART 1 - THE SCIENCE CHAPTER 1 Houston, We Have a Problem! How to Think Outside the Box to Solve a Global Health Crisis CHAPTER 2 I am a Product of My Generation: The Truth About How I Got Here CHAPTER 3 The Apple Can Land Far from the Tree, If You Give it a Push: How A Conventionally-Trained Doctor Turned into a Functional Medicine Fanatic CHAPTER 4 Inflammation and Oxidative Stress: Unearthing the Root Causes of Chronic Disease CHAPTER 5 The Seven Biological Systems: Imbalances in Functional Systems Affect One Another and Spark the Fire of Illness CHAPTER 6 The Clues are in the History: How Your Story Can Help You Learn What You Need to Do to Protect Your Brain CHAPTER 7 Getting Around the Parts of the Brain: How Structure Relates to Function, When it Comes to Preventing Memory Loss PART 2 - THE STRATEGIES CHAPTER 8 Brain Tune Up! In the Office: How a Functional Medicine Practice Can Work for You CHAPTER 9 Sleep Is More Than A Time Of Rest: Get Your Zzzs to Protect Your Brain! CHAPTER 10 Movement and Exercise: How Physical Activity Prevents Memory Loss and Protects Your Brain by Amy Gordin, PT CHAPTER 11 Nutrition to Tune Up Your Brain: How Food Provides the Building Blocks to Brain Health by Angela Jenkins, RD, LD CHAPTER 12 To Om and Beyond: An Emotional and Spiritual Stress Resilience Practice Can Improve Your Memory and Grow Your Brain by Chuck Renner, OTR, CHT CHAPTER 13 Eureka! How to Use Supplements, Herbal Brain Enhancers, and Technology to Prevent Memory Loss and Protect Your Aging Brain EPILOGUE: The Road Back |
| alternative therapy for als: The Management of Motor Neurone Disease George M. Cochrane, 1987 |
| alternative therapy for als: Mitochondrial Dysfunction Lawrence H. Lash, Dean P. Jones, 2013-10-22 Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable. |
| alternative therapy for als: Amyotrophic Lateral Sclerosis Hiroshi Mitsumoto, MD, 2009-03-16 ALS, also known as Lou Gehrig's disease, cannot be cured but it can be treated. A great deal can be done to treat the symptoms of ALS, to improve an individual's quality of life, and to help families, caregivers, and loved ones to cope with the disease. This extensively revised and rewritten new edition of the bestselling Amyotrophic Lateral Sclerosis: A Guide For Patients and Families addresses all of those needs, and brings up-to-date important information to those living with the reality of ALS. The book is completely revised throughout and contains NEW information on: Recently developed approaches to treating ALS symptoms Use of non-invasive ventilators Multidisciplinary team care New guidelines being developed by the American Academy of Neurology for patients with ALS The use of riluzole (Rilutek) to treat ALS Amyotrophic Lateral Sclerosis covers every aspect of the management of ALS, from clinical features of the disease, to diagnosis, to an overview of symptom management. Major sections deal with medical and rehabilitative management, living with ALS, managing advanced disease, end-of-life issues, and resources that can provide support and assistance in this time of need. |
| alternative therapy for als: Alternative Medicine for the Elderly P. Cherniack, 2003-04-23 This book on complementary alternative medicine (CAM) for the Elderly provides a critical and objective evaluation of alternative medical therapy for the elderly. The focus on practical aspects such as adverse effects and general risks of various therapeutic methods makes it a valuable reference book for the general practitioner, for geriatricians and professionals within the area of alternative medicine, but also for interested laypeople. In the three sections, Epidemiology, Types of CAM, and Common Medical Problems and CAM, a broad range of issues are covered. They range from drug compliance in elderly people to CAM in the treatment of specific conditions such as pulmonary diseases, arthritis or cancer. The above features and in particular the unbiased approach to discuss the pros and cons of CAM make this publication a must-have for everybody searching for detailed information on alternative medicine for the elderly. |
| alternative therapy for als: Snake Oil Science R. Barker Bausell PhD, 2009-07-31 Millions of people worldwide swear by such therapies as acupuncture, herbal cures, and homeopathic remedies. Indeed, complementary and alternative medicine is embraced by a broad spectrum of society, from ordinary people, to scientists and physicians, to celebrities such as Prince Charles and Oprah Winfrey. In the tradition of Michael Shermers Why People Believe Weird Things and Robert Parks's Voodoo Science, Barker Bausell provides an engaging look at the scientific evidence for complementary and alternative medicine (CAM) and at the logical, psychological, and physiological pitfalls that lead otherwise intelligent people--including researchers, physicians, and therapists--to endorse these cures. The books ultimate goal is to reveal not whether these therapies work--as Bausell explains, most do work, although weakly and temporarily--but whether they work for the reasons their proponents believe. Indeed, as Bausell reveals, it is the placebo effect that accounts for most of the positive results. He explores this remarkable phenomenon--the biological and chemical evidence for the placebo effect, how it works in the body, and why research on any therapy that does not factor in the placebo effect will inevitably produce false results. By contrast, as Bausell shows in an impressive survey of research from high-quality scientific journals and systematic reviews, studies employing credible placebo controls do not indicate positive effects for CAM therapies over and above those attributable to random chance. Here is not only an entertaining critique of the strangely zealous world of CAM belief and practice, but it also a first-rate introduction to how to correctly interpret scientific research of any sort. Readers will come away with a solid understanding of good vs. bad research practice and a healthy skepticism of claims about the latest miracle cure, be it St. John's Wort for depression or acupuncture for chronic pain. |
| alternative therapy for als: Ask a Manager Alison Green, 2018-05-01 From the creator of the popular website Ask a Manager and New York’s work-advice columnist comes a witty, practical guide to 200 difficult professional conversations—featuring all-new advice! There’s a reason Alison Green has been called “the Dear Abby of the work world.” Ten years as a workplace-advice columnist have taught her that people avoid awkward conversations in the office because they simply don’t know what to say. Thankfully, Green does—and in this incredibly helpful book, she tackles the tough discussions you may need to have during your career. You’ll learn what to say when • coworkers push their work on you—then take credit for it • you accidentally trash-talk someone in an email then hit “reply all” • you’re being micromanaged—or not being managed at all • you catch a colleague in a lie • your boss seems unhappy with your work • your cubemate’s loud speakerphone is making you homicidal • you got drunk at the holiday party Praise for Ask a Manager “A must-read for anyone who works . . . [Alison Green’s] advice boils down to the idea that you should be professional (even when others are not) and that communicating in a straightforward manner with candor and kindness will get you far, no matter where you work.”—Booklist (starred review) “The author’s friendly, warm, no-nonsense writing is a pleasure to read, and her advice can be widely applied to relationships in all areas of readers’ lives. Ideal for anyone new to the job market or new to management, or anyone hoping to improve their work experience.”—Library Journal (starred review) “I am a huge fan of Alison Green’s Ask a Manager column. This book is even better. It teaches us how to deal with many of the most vexing big and little problems in our workplaces—and to do so with grace, confidence, and a sense of humor.”—Robert Sutton, Stanford professor and author of The No Asshole Rule and The Asshole Survival Guide “Ask a Manager is the ultimate playbook for navigating the traditional workforce in a diplomatic but firm way.”—Erin Lowry, author of Broke Millennial: Stop Scraping By and Get Your Financial Life Together |
| alternative therapy for als: Amyotrophic Lateral Sclerosis Hiroshi Mitsumoto, David A. Chad, Erik P. Pioro, 1998 This volume provides comprehensive background for understanding amyotrophic lateral sclerosis (ALS) and a critical review of research. It points out the distinguishing characteristics of the disease and testing procedures for reliable diagnosis. |
| alternative therapy for als: Complementary & Alternative Therapies in Nursing Ruth Lindquist, Mariah Snyder, PhD, Mary Frances Tracy, 2014 Print+CourseSmart |
| alternative therapy for als: The Psychopath Test Jon Ronson, 2011-06-03 What if society wasn't fundamentally rational, but was motivated by insanity? This thought sets Jon Ronson on an utterly compelling adventure into the world of madness. Along the way, Jon meets psychopaths, those whose lives have been touched by madness and those whose job it is to diagnose it, including the influential psychologist who developed the Psychopath Test, from whom Jon learns the art of psychopath-spotting. A skill which seemingly reveals that madness could indeed be at the heart of everything . . . Combining Jon Ronson's trademark humour, charm and investigative incision, The Psychopath Test is both entertaining and honest, unearthing dangerous truths and asking serious questions about how we define normality in a world where we are increasingly judged by our maddest edges. 'The belly laughs come thick and fast – my God, he is funny . . . provocative and interesting' – Observer |
| alternative therapy for als: TDP-43 and Neurodegeneration Vijay Kumar, Manoj Kumar Jaiswal, 2021-10-27 Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43's structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders. Reviews TDP-43 structure, folding, function, and pathology Identifies TDP-43 role in ALS, FTP, and other neurodegenerative diseases Presents a systems and precision biology perspective of TDP-43 Discusses therapeutics of TDP-43 proteinopathies Translates bench research to application bedside |
| alternative therapy for als: Pathology, Prevention and Therapeutics of Neurodegenerative Disease Sarika Singh, Neeraj Joshi, 2018-09-24 This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative diseases |
| alternative therapy for als: The Health Effects of Cannabis and Cannabinoids National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Population Health and Public Health Practice, Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda, 2017-03-31 Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€that summarizes and prioritizes pressing research needs. |
| alternative therapy for als: Therapy in Sleep Medicine E-Book Teri J. Barkoukis, Jean K. Matheson, Richard Ferber, Karl Doghramji, 2011-10-31 Therapy in Sleep Medicine, by Drs. Teri J. Barkoukis, Jean K. Matheson, Richard Ferber, and Karl Doghrami, provides the clinically focused coverage you need for rapid diagnosis and effective treatment of sleep disorders. A multidisciplinary team of leading authorities presents the latest on sleep breathing disorders (including obstructive sleep apnea), neuropharmacology, parasomnias, neurologic disorders affecting sleep, sleep therapy for women, sleep therapy in geriatric patients, controversies, and future trends in therapy in a highly illustrated, easy-to-follow format. Diagnose and treat patients effectively with complete coverage of the full range of sleep disorders. Find diagnostic and treatment information quickly and easily thanks to a highly illustrated, easy-to-read format that highlights key details. Stay current on discussions of hot topics, including sleep breathing disorders (including obstructive sleep apnea), neuropharmacology, parasomnias, neurologic disorders affecting sleep, sleep therapy for women, sleep therapy in geriatric patients, controversies, and future trends in therapy. Tap into the expertise of a multidisciplinary team of leading authorities for well-rounded, trusted guidance. |
| alternative therapy for als: Navigating Life with Amyotrophic Lateral Sclerosis Mark B. Bromberg, Diane Banks Bromberg, 2017-04-03 Navigating Life with Amyotrophic Lateral Sclerosis provides accessible, comprehensive, and up-to-date information about the challenges patients, family members, and caregivers face when confronted by ALS, a disease that affects approximately 5,600 Americans every year, with as many as 30,000 people managing the disease at any given time. ALS is a difficult disease for the patient and is also challenging for the caregiver and family as there are many questions, issues relating to care, and problems to manage. This guide covers all aspects of managing ALS, from the onset of symptoms, diagnosis, treatments, and coping strategies, to the use of home health care or hospice, and new research in the field. The book also sheds lights on difficult topics, such as end-of-life care and managing legal affairs. Navigating Life with Amyotrophic Lateral Sclerosis is unique because it covers two perspectives: one author is a neurologist with 30 years of experience treating ALS patients, and the other author experienced first-hand the issues in providing care for a parent with ALS. Formatted in a question-and-answer style, peppered throughout with patient stories, and with sections devoted to family members and caregivers, this compassionate resource provides guidance to those seeking to understand how to live with this disease. |
| alternative therapy for als: Therapeutic Uses of Cannabis British Medical Association, 1997-11-18 At the last Annual Representative Meeting of the British Medical Association a motion was passed that `certain additional cannabinoids should be legalized for wider medicinal use.'' This report supports this landmark statement by reviewing the scientific evidence for the therapeutic use of cannabinoids and sets the agenda for change. It will be welcomed by those who believe that cannabinoids can be used in medical treatment. The report discusses in a clear and readable form the use and adverse effects of the drug for nausea, multiple sclerosis, pain, epilepsy, glaucoma, and asthma. |
| alternative therapy for als: Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies OECD, World Health Organization, 2019-10-17 This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies. |
| alternative therapy for als: Anesthesia and Uncommon Diseases E-Book Lee A. Fleisher, 2012-05-01 Your awareness of uncommon diseases and possible complications is vital to successful anesthetic patient management. Anesthesia and Uncommon Diseases, 6th Edition, brings you up to date with new information on less commonly seen diseases and conditions, including the latest evidence and management guidelines. This unique medical reference book is essential for a complete understanding of today's best options and potential difficulties in anesthesia. - Improve your ability to successfully manage every patient, including those with rare diseases or conditions. - Avoid complications with unique coverage of an important aspect of anesthetic management. - Access the complete contents and illustrations online at www.expertconsult.com - fully searchable! - Stay current with all-new chapters on adult congenital heart disease, rheumatic diseases, and the cancer patient, plus many more revisions throughout. - Get outstanding visual guidance with hundreds of illustrations, now in full color. |
| alternative therapy for als: Current Research in Acupuncture Ying Xia, Guanghong Ding, Gen-Cheng Wu, 2012-08-09 Written by over 60 scientists and clincicians from the United States, mainland China, Germany, Australia, Japan, Sweden, Portugal and Hong Kong, Current Research in Acupuncture discusses recent advances in acupuncture research in a modern scientific language. The first 5 chapters investigate the basic mechanisms of acupuncture. Later chapters explore topics including acupuncture treatment and potential mechanisms for epilepsy, Parkinson’s diseases, neurodegenerative disorders such as Alzheimer’s disease, vascular cognitive impairment, aging, anxiety, polycystic ovary syndrome, pain, nerve root cervical spondylosis, stroke, imflamation, myocardial ischemia and other cardiovascular diseases. Following the translational and clinical discussions, 4 chapters present new prospects for acupuncture theories and applications. The final chapter comments on the pitfalls and problems of the previous studies and suggests direction for future research towards in-depth understanding of acupuncture, along with better application of acupuncture in modern medicine. Each chapter is written by one or more experts in the field. This unique book provides a broad perspective on the principles of acupuncture for acupuncture researchers and neuroscientists. The laboratory and clinical investigations of various acupoints and optimal conditions provide unique clues to acupuncturists for improved clinical efficacy. For a medical student, this book is a modern course in ancient Traditional Chinese Medicine, especially acupuncture. Ying Xia, the chief editor, is Professor and Vice-Chairman of the Department of Neurosurgery at The University of Texas Medical School in Houston, Texas, USA. Guanghong Ding is Professor in the Department of Mechanics and Engineering Science at Fudan University and Director of Shanghai Research Center for Acupuncture and Meridians, Shanghai, China. Gen-Cheng Wu is Professor of Neurobiology; Chairman, Department of Integrative Medicine and Neurobiology; Director, Institute of Acupuncture Research; and Director, WHO Collaborating Center for Traditional Medicine, at Shanghai Medical College of Fudan University, Shanghai, China. |
| alternative therapy for als: Augie's Quest Augie Nieto, T.R. Pearson, 2011-01-15 What happens to orphan diseases that aren't big enough profit centers for the pharmaceutical industry or get caught in the web of government funding and academic research? Augie Nieto found out in the spring of 2005: At forty-seven years old he was diagnosed with ALS. Devastated, Augie struggled with depression and attempted suicide. When he awoke from a coma, with friends and family surrounding him, his sense of faith and mission were renewed. Fast-forward one year: Augie and his wife, Lynne, were profiled as Real Heroes on the Today show. Their determination to beat the disease had already led to major overhauls in the way ALS research was conducted. In partnership with the Muscular Dystrophy Association, Augie had set up a foundation and lab to coordinate and oversee ALS research and testing across the globe. By centralizing operations and championing an entrepreneurial approach to medical research, Augie and his team accomplished remarkable results in less than two years. Part inspiration, part business innovation, Augie's Quest illustrates how one person can make a meaningful difference. Praise for Augie Nieto: George H. W. Bush, former U.S. president: Your contributions to the fitness industry are well known, and your dedication an inspiration. Lance Armstrong, seven-time Le Tour de France champion: I think it says a lot about Augie, the fact that everybody came together regardless of whether or not it's for competing gyms or competing companies that make equipment. They all say, this is one of our own; this is a guy who's committed his life to our industry and has been dealt a serious blow. We're going to be there for him, we're going to say, we're here for you and we're part of the Quest. Arnold Schwarzenegger, governor of California: Your success has been incredible. But you are so much more than just a successful businessman. You are the greatest husband, a great father, and a terrific friend. So, |
| alternative therapy for als: ALS Saved My Life... Until It Didn't Dr. Jenni Kleinman Berebitsky, Joyce Kleinman, Elizabeth Flynn (Non-fiction writer), 2018-03-18 The author shares her insights and perspectives on living with ALS, or Lou Gehrig's disease, sharing both her thoughts on life and happiness as well as practical ideas for daily living with this progressive neuromuscular disease. |
| alternative therapy for als: Motivational Enhancement Therapy Manual , 1992 |
| alternative therapy for als: I Had a Black Dog Matthew Johnstone, 2012-03-01 'I Had a Black Dog says with wit, insight, economy and complete understanding what other books take 300 pages to say. Brilliant and indispensable.' - Stephen Fry 'Finally, a book about depression that isn't a prescriptive self-help manual. Johnston's deftly expresses how lonely and isolating depression can be for sufferers. Poignant and humorous in equal measure.' Sunday Times There are many different breeds of Black Dog affecting millions of people from all walks of life. The Black Dog is an equal opportunity mongrel. It was Winston Churchill who popularized the phrase Black Dog to describe the bouts of depression he experienced for much of his life. Matthew Johnstone, a sufferer himself, has written and illustrated this moving and uplifting insight into what it is like to have a Black Dog as a companion and how he learned to tame it and bring it to heel. |
| alternative therapy for als: Volume 16: How to Detect and Handle Outliers Boris Iglewicz, David C. Hoaglin, 1993-01-08 Outliers are the key focus of this book. The authors concentrate on the practical aspects of dealing with outliers in the forms of data that arise most often in applications: single and multiple samples, linear regression, and factorial experiments. Available only as an E-Book. |
| alternative therapy for als: Palliative Care in Amyotrophic Lateral Sclerosis David Oliver, Gian Domenico Borasio, Wendy Johnston, 2014-03-20 Amytrophic Lateral Sclerosis (ALS or motor neurone disease) is a progressive neurodegenerative disease that can cause profound suffering for both the patient and their family. Whilst new treatments for ALS are being developed, these are not curative and offer only the potential to slow its progression. Palliative care must therefore be integral to the clinical approach to the disease. Palliative Care in Amyotrophic Lateral Sclerosis: From diagnosis to bereavement reflects the wide scope of this care; it must cover not just the terminal phase, but support the patient and their family from the onset of the disease. Both the multidisciplinary palliative care team and the neurology team are essential in providing a high standard of care and allowing quality of life (both patient and carer) to be maintained. Clear guidelines are provided to address care throughout the disease process. Control of symptoms is covered alongside the psychosocial care of patients and their families. Case studies are used to emphasise the complexity of the care needs and involvement of the patient and family, culminating in discussion of bereavement. Different models of care are explored, and this new edition utilizes the increase in both the evidence-base and available literature on the subject. New topics discussed include complementary therapies, personal and family experiences of ALS, new genetics research, and updated guidelines for patient care, to ensure this new edition remains the essential guide to palliative care in ALS. |
| alternative therapy for als: Itch E. Carstens, Tasuku Akiyama, 2014-02-25 Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment. |
| alternative therapy for als: Exploring Complementary and Alternative Medicinal Products in Disease Therapy Eshiet, Etetor Roland, 2023-08-29 Recent breakthroughs in science and technology have led to a concomitant growth in exploratory studies into the definitive properties of traditional therapies employed in medicine and pharmacology. Complementary and alternative medicine (CAM) involves a diverse range of medicinal and health practices and products that are typically not part of conventional medicine. Presently, there are a multitude of research studies investigating the promise and potential of CAM products in disease therapy. A record of concentric investigations into the therapeutic properties of products may assure researchers and the public of safety, efficacy, and beneficent implications. While big pharma and the biotech industry race to produce vaccines and effective and efficient drugs, especially in the times of a pandemic, it is an excellent opportunity to discuss complementary and alternative medicinal products. Research investigations continue to exhibit the enormous possibilities of CAM and the financial benefits thereof. Exploring Complementary and Alternative Medicinal Products in Disease Therapy is an innovative reference book that presents a holistic overview and makes an intelligent argument for an aggressive, sustained research into the capabilities of CAM in disease therapy applications. The chapters are a compendium of recent results of CAM in areas such as topical pre-clinical and clinical trial studies undertaking this effort. They demonstrate one or more instances where a continuum of research findings on certain CAM products are indicative of the potential CAM has in the treatment of a plethora of diseases and comorbidities. This book is a valuable reference tool for pharmaceutical companies, healthcare providers, professionals and practitioners, epidemiologists, researchers, academicians, and students interested in the safety, efficiency, beneficence, and cost implications of employing CAM in patient care. |
ALTERNATIVE Definition & Meaning - Merriam-Webster
The meaning of ALTERNATIVE is offering or expressing a choice. How to use alternative in a sentence. Synonym Discussion of Alternative.
ALTERNATIVE | English meaning - Cambridge Dictionary
ALTERNATIVE definition: 1. An alternative plan or method is one that you can use if you do not want to use another one: 2…. Learn more.
ALTERNATIVE Definition & Meaning | Dictionary.com
Alternative definition: a choice limited to one of two or more possibilities, as of things, propositions, or courses of action, the selection of which precludes any other possibility.. See …
ALTERNATIVE definition and meaning | Collins English Dictionary
Alternative is used to describe something that is different from the usual things of its kind, or the usual ways of doing something, in modern Western society. For example, an alternative …
Alternative - Wikipedia
Alternative (Kamen Rider), a character in the Japanese TV series Kamen Rider RyukiAlternative comics, or independent comics are an alternative to mainstream superhero comics; Alternative …
Alternative - definition of alternative by The Free Dictionary
Define alternative. alternative synonyms, alternative pronunciation, alternative translation, English dictionary definition of alternative. n. 1. a. One of a number of possible choices or courses of …
alternative noun - Definition, pictures, pronunciation and usage …
alternative something that you can choose to have or do out of two or more possibilities: You can be paid in cash weekly or by cheque monthly: those are the two alternatives. option, choice or …
What does alternative mean? - Definitions.net
Alternative refers to one or more options or choices available as a substitute or replacement to the existing one. It generally denotes the possibility of choice between two or more things. In …
Alternative Definition & Meaning | Britannica Dictionary
ALTERNATIVE meaning: 1 : offering or expressing a choice; 2 : not usual or traditional often used to describe something that is more natural or that causes less pollution than the usual product, …
alternative - WordReference.com Dictionary of English
a choice among only two possibilities such that if one is chosen, the other cannot be chosen: Here are the alternatives: surrender or die. one of these choices: The alternative to riding is walking. …
ALTERNATIVE Definition & Meaning - Merriam-Webster
The meaning of ALTERNATIVE is offering or expressing a choice. How to use alternative in a sentence. Synonym Discussion of Alternative.
ALTERNATIVE | English meaning - Cambridge Dictionary
ALTERNATIVE definition: 1. An alternative plan or method is one that you can use if you do not want to use another one: 2…. Learn more.
ALTERNATIVE Definition & Meaning | Dictionary.com
Alternative definition: a choice limited to one of two or more possibilities, as of things, propositions, or courses of action, the selection of which precludes any other possibility.. See examples of …
ALTERNATIVE definition and meaning | Collins English Dictionary
Alternative is used to describe something that is different from the usual things of its kind, or the usual ways of doing something, in modern Western society. For example, an alternative …
Alternative - Wikipedia
Alternative (Kamen Rider), a character in the Japanese TV series Kamen Rider RyukiAlternative comics, or independent comics are an alternative to mainstream superhero comics; Alternative …
Alternative - definition of alternative by The Free Dictionary
Define alternative. alternative synonyms, alternative pronunciation, alternative translation, English dictionary definition of alternative. n. 1. a. One of a number of possible choices or courses of …
alternative noun - Definition, pictures, pronunciation and usage …
alternative something that you can choose to have or do out of two or more possibilities: You can be paid in cash weekly or by cheque monthly: those are the two alternatives. option, choice or …
What does alternative mean? - Definitions.net
Alternative refers to one or more options or choices available as a substitute or replacement to the existing one. It generally denotes the possibility of choice between two or more things. In …
Alternative Definition & Meaning | Britannica Dictionary
ALTERNATIVE meaning: 1 : offering or expressing a choice; 2 : not usual or traditional often used to describe something that is more natural or that causes less pollution than the usual product, …
alternative - WordReference.com Dictionary of English
a choice among only two possibilities such that if one is chosen, the other cannot be chosen: Here are the alternatives: surrender or die. one of these choices: The alternative to riding is walking. …
