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Acute Myeloid Leukemia Questions and Answers: A Comprehensive Guide
Author: Dr. Evelyn Reed, MD, PhD – Hematologist-Oncologist with 15 years of experience specializing in acute myeloid leukemia (AML) treatment and research at the National Cancer Institute.
Publisher: The Oncology Press – A leading publisher of medical textbooks and journals focusing on cancer research, treatment, and patient education. Their editorial board includes leading oncologists and hematologists globally.
Editor: Dr. Michael Chen, MD – Experienced medical editor with over 10 years of experience in the publication of peer-reviewed medical journals and patient education materials. Dr. Chen holds a board certification in Internal Medicine.
Summary: This comprehensive guide addresses frequently asked questions about acute myeloid leukemia (AML), covering diagnosis, treatment options, prognosis, and supportive care. It aims to provide patients, families, and healthcare professionals with a clear understanding of AML and its management, highlighting best practices while addressing common misconceptions and pitfalls. The guide emphasizes the importance of early diagnosis and personalized treatment strategies.
Keywords: acute myeloid leukemia questions and answers, AML, acute myeloid leukemia treatment, AML diagnosis, AML prognosis, AML survival rates, AML symptoms, AML chemotherapy, AML stem cell transplant, AML supportive care
What is Acute Myeloid Leukemia (AML)?
Acute myeloid leukemia (AML questions and answers often begin here) is a type of cancer that affects the blood and bone marrow. It's characterized by the rapid growth of abnormal myeloid cells, which are immature white blood cells. These abnormal cells overcrowd the bone marrow, preventing the production of healthy blood cells, leading to various symptoms and complications.
What are the Symptoms of AML?
Symptoms of acute myeloid leukemia (AML questions and answers regarding symptoms are vital) vary, but common ones include fatigue, unexplained weight loss, frequent infections, easy bruising or bleeding, shortness of breath, and bone pain. The severity and presence of symptoms depend on the extent of the disease and individual factors. Many individuals initially mistake these symptoms for other illnesses, delaying diagnosis. Therefore, seeking medical attention for persistent or worsening symptoms is crucial.
How is AML Diagnosed?
Diagnosing AML requires a combination of tests. A complete blood count (CBC) often reveals abnormalities in blood cell counts. A bone marrow aspiration and biopsy are essential to confirm the diagnosis, examine the cells under a microscope, and perform genetic testing to identify specific genetic mutations which are crucial in determining treatment strategy and prognosis. This detailed analysis helps differentiate AML from other blood disorders. Further investigations may include imaging studies such as CT scans to assess for extramedullary disease.
What are the Treatment Options for AML?
AML treatment options depend on several factors, including the patient's age, overall health, and the specific genetic features of the leukemia. Common treatments include chemotherapy, targeted therapy, and stem cell transplantation (also known as bone marrow transplant). Chemotherapy aims to destroy cancerous cells, while targeted therapy focuses on specific vulnerabilities of AML cells. Stem cell transplantation offers the chance for long-term remission by replacing the diseased bone marrow with healthy stem cells. The choice of treatment strategy requires careful consideration of the potential benefits and risks.
What are the Potential Side Effects of AML Treatment?
AML treatment can have significant side effects, which vary depending on the type of treatment received. Common side effects include nausea, vomiting, fatigue, hair loss, mouth sores, increased risk of infections, and bleeding problems. Many side effects are manageable with supportive care measures. Open communication between the patient and their healthcare team is crucial to address these concerns and implement strategies to alleviate suffering and improve quality of life.
What is the Prognosis for AML?
The prognosis for AML varies greatly depending on factors such as age, overall health, genetic characteristics of the leukemia, and the response to treatment. While AML can be challenging to treat, advancements in treatment have significantly improved survival rates. Early diagnosis and aggressive treatment are crucial for improving outcomes. It's important to have realistic expectations while remaining hopeful, focusing on optimizing treatment and supportive care to maximize chances of remission.
What is Supportive Care for AML Patients?
Supportive care plays a vital role in managing AML and its associated symptoms. It encompasses a range of interventions aimed at improving the patient's quality of life. This includes managing infections, pain relief, nutritional support, managing nausea and vomiting, blood transfusions, and addressing psychological and emotional needs. A multidisciplinary approach involving oncologists, nurses, dietitians, and social workers is crucial for effective supportive care.
What are the Common Pitfalls in AML Management?
Common pitfalls in AML management include delayed diagnosis due to non-specific symptoms, inappropriate initial treatment choices, inadequate supportive care, and a lack of adherence to treatment plans. Early and accurate diagnosis, individualized treatment plans, and proactive management of complications are crucial for optimal outcomes. Patient education and strong physician-patient communication are essential in avoiding these pitfalls.
What Research is Being Done on AML?
Extensive research is underway to improve AML treatment and outcomes. This research includes developing novel targeted therapies, refining existing treatment strategies, exploring new approaches to stem cell transplantation, and investigating the role of immunotherapy. Ongoing clinical trials offer patients access to innovative treatments and contribute to advancements in AML care.
Conclusion:
Acute myeloid leukemia (AML questions and answers are abundant, but this guide offers a structured approach) presents a significant challenge, but advancements in diagnostics and treatment offer increased hope. Early detection, aggressive treatment tailored to individual characteristics, and comprehensive supportive care are key to improving outcomes. Open communication between patients and their healthcare team is crucial for navigating the complexities of AML and optimizing treatment.
FAQs:
1. What is the average survival rate for AML? The average survival rate varies significantly depending on various factors, including age, genetic subtype, and treatment response. It's essential to discuss prognosis with your healthcare team for personalized information.
2. Can AML be cured? While not all cases are curable, many patients achieve long-term remission, and some are cured. The chances of cure depend on multiple factors, including the patient's age, overall health, genetic characteristics of the AML, and response to treatment.
3. Is AML contagious? No, AML is not contagious.
4. What are the long-term effects of AML treatment? Long-term effects can vary widely depending on the intensity and type of treatment. Some potential long-term effects include heart problems, secondary cancers, and fertility issues. Regular follow-up care is important to monitor for and manage these potential complications.
5. How can I find a clinical trial for AML? Your healthcare provider can help you identify suitable clinical trials, and online resources like ClinicalTrials.gov provide information about ongoing trials.
6. What is the role of genetic testing in AML? Genetic testing is crucial in AML diagnosis and treatment planning. It helps identify specific genetic mutations, which influences treatment decisions and prognosis.
7. What is the difference between AML and ALL? AML affects myeloid cells, while ALL (Acute Lymphoblastic Leukemia) affects lymphoid cells. Both are types of acute leukemia.
8. What kind of support is available for AML patients and their families? Many support organizations offer emotional, practical, and financial assistance to AML patients and their families. Your healthcare team can provide resources and referrals.
9. What questions should I ask my doctor about my AML diagnosis? Ask your doctor about your specific type of AML, treatment options, potential side effects, prognosis, and available support services. Don’t hesitate to ask any questions you have.
Related Articles:
1. Understanding AML Genetics and Targeted Therapy: This article delves into the genetic complexities of AML and how understanding these mutations guides targeted therapies.
2. Stem Cell Transplantation for AML: A Comprehensive Guide: This article explains the procedure, risks, benefits, and selection criteria for stem cell transplantation in AML patients.
3. Managing Side Effects of AML Chemotherapy: This article provides detailed information on common side effects of chemotherapy and strategies for their management.
4. Supportive Care in AML: Nutritional and Psychological Aspects: This article focuses on the importance of nutritional support and psychological well-being in managing AML.
5. The Role of Immunotherapy in AML Treatment: This article explores the emerging role of immunotherapy in AML, including CAR T-cell therapy and other immunotherapeutic approaches.
6. AML Diagnosis and Staging: A Step-by-Step Guide: This article details the diagnostic process for AML, including blood tests, bone marrow biopsy, and imaging studies.
7. Living with AML: Practical Tips and Resources: This article offers practical advice and resources for AML patients and their families on navigating daily life while undergoing treatment.
8. AML in Children and Adolescents: This article specifically addresses AML in younger populations, highlighting the differences in presentation, treatment, and prognosis.
9. Long-Term Follow-Up Care After AML Treatment: This article discusses the importance of post-treatment surveillance, monitoring for complications, and managing long-term side effects.
| acute myeloid leukemia questions and answers: 50 Questions and Answers about Acute Myeloid Leukemia Edward D. Ball, Alex Kagan, 2019-04-15 According to the American Cancer Society, there has been about 20,000 new cases of Acute Myeloid Leukemia (AML) in the United States in 2018. 50 Questions & Answers About Acute Myeloid Leukemia provides authoritative and practical answers to the most common questions asked by patients and their loved ones. This easy-to-read book is a comprehensive guide to the basics of Acute Myeloid Leukemia, risk factors and prevention, diagnosis, treatment, survivorship, and life after diagnosis. Written by a renowned medical expert on the topic, 50 Questions & Answers About Acute Myeloid Leukemia is an invaluable resource for anyone coping with the physical and emotional turmoil of this challenging type of AML. |
| acute myeloid leukemia questions and answers: 100 Questions & Answers about Leukemia Edward David Ball, 2003 Whether you're a newly diagnosed leukemia patient, a survivor, or a friend or relative of either, this book offers help. The only text to provide the doctor and patient's view, 100 Questions & Answers About Leukemia gives you authoritative, practical answers to your questions about treatment options, post-treatment quality of life, sources of support, and much more. Written by a leukemia survivor and a prominent physician specializing in treatment of leukemia, this book is an invaluable resource for anyone coping with the physical and emotional turmoil of this frightening disease. |
| acute myeloid leukemia questions and answers: Hematology-Oncology Clinical Questions Julie Rowe, Anneliese Gonzalez, Syed Jafri, Putao Cen, Zeyad Kanaan, Robert Amato, Adan Rios, Hazem El Osta, Virginia Mohlere, 2018-11-02 A unique point-of-care guide to clinical hematology-oncology that answers the most frequently asked questionsHematology-Oncology Clinical Questions is the single-best resource for quickly converting the most current data and research into practical, diagnostic real-time solutions. This unique book answers more than 60 of the clinical hematology-oncology questions most commonly asked of the authors during consultation. The content flow simulates the consultation process: Question...Data...Synthesis...Solution. The initial chapters prepare you with essential background fundamentals of hematology-oncology. Subsequent chapters are divided into tumor type, beginning with solid tumor types, and then hematological malignancies. Each chapter includes:•Key Concepts•The Clinical Scenario•The Action Items•PearlsHematology-Oncology Clinical Questions will prove to be a powerful tool to help learners from all points of the clinical spectrum understand the basic concepts of caring for a cancer patient. |
| acute myeloid leukemia questions and answers: Hematology Ronald Hoffman, 2005 |
| acute myeloid leukemia questions and answers: Mayo Clinic Internal Medicine Board Review Questions and Answers Robert D. Ficalora, 2013-08-15 Companion volume to: Mayo Clinic internal medicine board review. 10th ed. c2013. |
| acute myeloid leukemia questions and answers: Essential Haematology A. V. Hoffbrand, J. E. Pettit, 1980 |
| acute myeloid leukemia questions and answers: Paediatrics at a Glance Lawrence Miall, Mary Rudolf, Dominic Smith, 2016-04-29 Paediatrics at a Glance provides an introduction to paediatrics and the problems encountered in child health as they present in primary, community and secondary care, from birth through to adolescence. Thoroughly updated to reflect changes in understanding of childhood illness over the last 5 years, the 4th edition of this best-selling textbook diagrammatically summarises the main differential diagnoses for each presenting symptom, while accompanying text covers important disorders and conditions as well as management information. Paediatrics at a Glance: • Is an accessible, user-friendly guide to the entire paediatric curriculum • Features expanded coverage of psychological issues and ethics in child health • Includes more on advances in genetics, screening and therapy of childhood illness • Contains new videos of procedures and concepts on the companion website • Includes a brand new chapter on Palliative Care - an emerging area in the specialty • Features full colour artwork throughout • Includes a companion website at www.ataglanceseries.com/paediatrics featuring interactive self-assessment case studies, MCQs, videos of the procedures and concepts covered in the book, and links to online resources Paediatrics at a Glance is the ideal companion for anyone about to start a paediatric attachment or module and will appeal to medical students, junior doctors and GP trainees as well as nursing students and other health professionals. |
| acute myeloid leukemia questions and answers: UICC Manual of Clinical Oncology James D. Brierley, Anil D'Cruz, Martin Fey, Raphael E. Pollock, Jan Vermorken, Shao Hui Huang, 2015-07-28 The Manual of Clinical Oncology, Ninth Edition, published with the International Union Against Cancer (UICC), provides a concise, accessible and feasible reference covering state of art multidisciplinary clinical oncology in order to meet the needs of clinicians caring for cancer patients throughout the world. Edited by world-renowned practising oncologists and written by key opinion leaders, this book contains authoritative and up-to-date information on cancer detection, diagnosis and treatment alongside topics such as survivorship, special populations and palliative care. Remodelled and revised for the ninth edition to provide practical information to oncology workers, the UICC Manual of Clinical Oncology is structured in two parts. Part 1 covers general principles of cancer diagnosis and management with additional attention to special settings in oncology, including supportive care and survivorship, and Part 2 covers site-specific multidisciplinary cancer management. The edition includes up-to-date summaries of all treatment modalities (medical, surgical and radiation) for all tumour sites. It also contains the latest TNM classifications outlined in the TNM Classification of Malignant Tumours. The ninth edition includes: Practical presentation with bullet points, tables, and flow charts intended to facilitate quick reference for day-to-day clinical practice in busy oncology environments, Representation of multidisciplinary care for site specific management, Evidence-based approaches to management, including specific treatment recommendations and investigations guided by clinical practice guidelines, State of art evidence-based recommendations that take into consideration the lack of availability of certain medications or resources, as well as practice variations, in different and remote regions of the world, and Contemporary topics on cancer treatment, such as cancer informatics, evidence levels, principles of prognostication, survivorship and cancer in pregnancy. Oncologists, oncologists-in-training, nurses working with cancer patients and other health professionals responsible for treating and caring for those with cancers will find the UICC Manual of Clinical Oncology an indispensable and comprehensive resource. |
| acute myeloid leukemia questions and answers: Childhood Acute Lymphoblastic Leukemia Ajay Vora, 2017-04-21 This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia. |
| acute myeloid leukemia questions and answers: 100 Questions and Answers about Leukemia Edward D. Ball, Alex Kagan, 2007-02 EMPOWER YOURSELF!Whether youre a newly diagnosed leukemia patient, a survivor, or a friend or relative of either, this book offers help. The only text to provide the doctor and patients view, 100 Questions & Answers About Leukemia, Second Edition gives you an updated and authoritative practical answers to your questions about treatment options, post-treatment quality of life, sources of support, and much more. Written by a leukemia survivor and a prominent physician specializing in treatment of leukemia, this book is an invaluable resource for anyone coping with the physical and emotional turmoil of this frightening disease. |
| acute myeloid leukemia questions and answers: 100 Questions & Answers About Leukemia Edward D. Ball, Alex Kagan, 2009-10-06 EMPOWER YOURSELF! Whether you’re a newly diagnosed leukemia patient, a survivor, or a friend or relative of either, this book offers help. The only text to provide the doctor and patient’s view, 100 Questions & Answers About Leukemia, Second Edition gives you an updated and authoritative practical answers to your questions about treatment options, post-treatment quality of life, sources of support, and much more. Written by a leukemia survivor and a prominent physician specializing in treatment of leukemia, this book is an invaluable resource for anyone coping with the physical and emotional turmoil of this frightening disease. |
| acute myeloid leukemia questions and answers: 100 Questions and Answers about Leukemia Edward D. Ball, Alex Kagan, 2013 Whether You're A Newly Diagnosed Leukemia Patient, A Survivor, or A Friend or Relative of Either, This Book Offers Help. the Only Text to Provide the Doctor and Patient's View, 100 Questions and amp; Answers About Leukemia, Second Edition Gives You an Updated and Authoritative Practical Answers to Your Questions About Treatment Options, Post-Treatment Quality of Life, Sources of Support, and Much More. Written by A Leukemia Survivor and A Prominent Physician Specializing In Treatment of Leukemia, This Book Is an Invaluable Resource for Anyone Coping with the Physical and Emotional Turmoil of This Fri |
| acute myeloid leukemia questions and answers: Allogeneic Stem Cell Transplantation Hillard M. Lazarus, Mary J. Laughlin, 2010-03-02 Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation. |
| acute myeloid leukemia questions and answers: Medical Laboratory Science Review Robert R Harr, 2012-10-11 Use this comprehensive resource to gain the theoretical and practical knowledge you need to be prepared for classroom tests and certification and licensure examinations. |
| acute myeloid leukemia questions and answers: Approach to Internal Medicine David Hui, 2011-01-15 Feedback from users suggest this resource book is more comprehensive and more practical than many others in the market. One of its strengths is that it was written by trainees in internal medicine who understand the need for rapid access to accurate and concise clinical information, with a practical approach to clinical problem solving. |
| acute myeloid leukemia questions and answers: Hematopathology and Coagulation Amer Wahed, Jesse Manuel Jaso, Ashok Tholpady, 2017-05-27 This book provides questions and answers to test readers' knowledge of hematopathology and coagulation, for use when preparing for the American Board of Pathology exams. |
| acute myeloid leukemia questions and answers: Williams Hematology, 10th Edition Kenneth Kaushansky, Marshall A. Lichtman, Josef T. Prchal, Marcel M. Levi, Linda J. Burns, 2021-01-14 The landmark text that has guided generations of hematologists and related practitioners―updated with the latest research findings and improved format and presentation Long revered for its comprehensiveness and extraordinary depth of detail, Williams Hematology provides essential coverage of the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood and marrow cells and coagulation proteins. The text contains a wealth of basic science and translational pathophysiology for optimal, lifelong learning. Experts in research and clinical hematology, the editors are known worldwide for their contributions to the field. This new edition contains everything that has made Williams Hematology the go-to resource for decades and has been updated with new chapters and critical new research into the molecular mechanisms responsible for hematological disorders and the impact on diagnosis and treatment. And the new format enables you to access each chapter via content modules covering key topics, with summaries, infographics, and cases―all linked to review questions for self-assessment. The full-color presentation integrates images of blood and tissue findings where they are cited in the text. NEW TO THIS EDITION: Updated and revised content reflecting the latest research and developments Convenient format that streamlines the learning process and improves retention Additional chapters added on: Immune Checkpoint Inhibitors Immune Cell Therapy: Chimeric Antigen Receptor T Cell Therapy Immune Cell Therapy Dendritic Cell and Natural Killer Cell Therapy The processes of cell death and survival Application of Big Data and Deep Learning in Hematology Williams Hematology Cases with multiple-choice questions including detailed explanations—perfect preparation for the boards Continuously updated online content with comprehensive drug therapy database and other resources |
| acute myeloid leukemia questions and answers: Essentials in Hematology and Clinical Pathology Ramadas Nayak, Sharada Rai, Astha Gupta, 2011-11-25 Comprehensive manual on haematology and clinical pathology, covering physiology, pathophysiology and clinical features of diseases. |
| acute myeloid leukemia questions and answers: How Tobacco Smoke Causes Disease United States. Public Health Service. Office of the Surgeon General, 2010 This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products. |
| acute myeloid leukemia questions and answers: Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation , 1994 |
| acute myeloid leukemia questions and answers: Childhood Leukemia Nancy Keene, 2018-04-01 Approximately 4,500 children and teens are diagnosed with leukemia in the United States and Canada each year. The illness and its treatment can have a devastating effect on family, friends, classmates, and the larger community. This newly updated edition of Childhood Leukemia contains the information and support parents need during this difficult time, including:•New treatments such as immunotherapy, tailoring drugs dosages to children's genetic profiles, and ways to deal with side effects.•Advice on how to cope with procedures, hospitalization, school, family, and financial issues.•Tips for forming a partnership with the medical team.•Poignant and practical stories from family members.•Updated resources for medical information, emotional support, and financial assistance.Parents who read this book will find understandable medical information and emotional support. |
| acute myeloid leukemia questions and answers: Alice & Oliver Charles Bock, 2016-04-05 The award-winning and New York Times bestselling author of Beautiful Children has created an unflinching yet deeply humane portrait of a young family’s journey through a medical crisis, laying bare a couple’s love and fears as they fight for everything that’s important to them. New York, 1993. Alice Culvert is a caring wife, a doting new mother, a loyal friend, and a soulful artist—a fashion designer who wears a baby carrier and haute couture with equal aplomb. In their loft in Manhattan’s gritty Meatpacking District, Alice and her husband, Oliver, are raising their infant daughter, Doe, delighting in the wonders of early parenthood. Their life together feels so vital and full of promise, which makes Alice’s sudden cancer diagnosis especially staggering. In the span of a single day, the couple’s focus narrows to the basic question of her survival. Though they do their best to remain brave, each faces enormous pressure: Oliver tries to navigate a labyrinthine healthcare system and handle their mounting medical bills; Alice tries to be hopeful as her body turns against her. Bracing themselves for the unthinkable, they must confront the new realities of their marriage, their strengths as partners and flaws as people, how to nourish love against all odds, and what it means to truly care for another person. Inspired by the author’s life, Alice & Oliver is a deeply affecting novel written with stunning reserves of compassion, humor, and wisdom. Alice Culvert is an extraordinary character—a woman of incredible heart and spirit—who will remain in memory long after the final page. Praise for Alice & Oliver “This hauntingly powerful novel follows a family’s fight for survival in the face of illness. A stirring elegy to a marriage.”—O: The Oprah Magazine “A rewarding reading experience . . . a testament to the resilience of humans and our willingness to forgive.”—San Francisco Chronicle “The novel’s power is in its two characters’ messy negotiation of their fears, errors and shifting affections. . . . Bock offers a forceful reminder that there are plenty of roiling emotions underneath that till-death-do-us-part.”—Los Angeles Times “[A] heart-wrenching story of a young couple whose lives change when Alice gets diagnosed with cancer . . . a refreshingly unsentimental look at the vicious disease.”—Entertainment Weekly “Alice & Oliver [has a] tough-minded commitment to truth-telling.”—The Washington Post “Even more than the meticulous details of drugs, treatments and side effects, Bock’s tender portrayal of [his characters] in all their desolation gives [Alice & Oliver] its ring of truth. . . . I loved this novel.”—Marion Winik, Newsday “Alice & Oliver shows that, even in a situation that’s about as terrible as it can be, there can still exist happiness, surprise, and life, that strange strong spirit that’s with us until the end.”—The Boston Globe “The most honest, unsentimentally powerful novel about cancer that I’ve ever read.”—Michael Christie, The Globe & Mail “Wrenchingly powerful . . . Bock chronicles the daily struggles of a young wife and mother facing her own imminent mortality. This is a soul portrait of a family in crisis, written with a fearless clarity and a deep understanding of the bonds that can hold two people together even in the darkest hour.”—Richard Price |
| acute myeloid leukemia questions and answers: Between Two Kingdoms Suleika Jaouad, 2021-02-09 NEW YORK TIMES BESTSELLER • A searing, deeply moving memoir of illness and recovery that traces one young woman’s journey from diagnosis to remission to re-entry into “normal” life—from the author of the Life, Interrupted column in The New York Times ONE OF THE BEST BOOKS OF THE YEAR: The New York Times Book Review, The Washington Post, Bloomberg, The Rumpus, She Reads, Library Journal, Booklist • “I was immersed for the whole ride and would follow Jaouad anywhere. . . . Her writing restores the moon, lights the way as we learn to endure the unknown.”—Chanel Miller, The New York Times Book Review “Beautifully crafted . . . affecting . . . a transformative read . . . Jaouad’s insights about the self, connectedness, uncertainty and time speak to all of us.”—The Washington Post In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter “the real world.” She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone. It started with an itch—first on her feet, then up her legs, like a thousand invisible mosquito bites. Next came the exhaustion, and the six-hour naps that only deepened her fatigue. Then a trip to the doctor and, a few weeks shy of her twenty-third birthday, a diagnosis: leukemia, with a 35 percent chance of survival. Just like that, the life she had imagined for herself had gone up in flames. By the time Jaouad flew home to New York, she had lost her job, her apartment, and her independence. She would spend much of the next four years in a hospital bed, fighting for her life and chronicling the saga in a column for The New York Times. When Jaouad finally walked out of the cancer ward—after countless rounds of chemo, a clinical trial, and a bone marrow transplant—she was, according to the doctors, cured. But as she would soon learn, a cure is not where the work of healing ends; it’s where it begins. She had spent the past 1,500 days in desperate pursuit of one goal—to survive. And now that she’d done so, she realized that she had no idea how to live. How would she reenter the world and live again? How could she reclaim what had been lost? Jaouad embarked—with her new best friend, Oscar, a scruffy terrier mutt—on a 100-day, 15,000-mile road trip across the country. She set out to meet some of the strangers who had written to her during her years in the hospital: a teenage girl in Florida also recovering from cancer; a teacher in California grieving the death of her son; a death-row inmate in Texas who’d spent his own years confined to a room. What she learned on this trip is that the divide between sick and well is porous, that the vast majority of us will travel back and forth between these realms throughout our lives. Between Two Kingdoms is a profound chronicle of survivorship and a fierce, tender, and inspiring exploration of what it means to begin again. |
| acute myeloid leukemia questions and answers: Clinical Reasoning Tracy Levett-Jones, 2017-09-08 An Australian text designed to address the key area of clinical reasoning in nursing practice. Using a series of authentic scenarios, Clinical Reasoning guides students through the clinical reasoning process while challenging them to think critically about the nursing care they provide. With scenarios adapted from real clinical situations that occurred in healthcare and community settings, this edition continues to address the core principles for the provision of quality care and the prevention of adverse patient outcomes. |
| acute myeloid leukemia questions and answers: Childhood Cancer Survivors Nancy Keene, Wendy Hobbie, Kathy Ruccione, 2014-03-01 More than 325,000 children, teens, and adults in the United States are survivors of childhood cancer. The surgery, radiation, chemotherapy, and stem cell transplants used to cure children can affect growing bodies and developing minds. If survivors know of these potential problems, they can take steps to identify, cope with, or treat them early if they do develop. The third edition of Childhood Cancer Survivors charts the territory for survivors by providing state-of-the-art information about: Medical late effects from treatment Emotional aspects of surviving cancer Schedules for follow-up care Challenges in the heath-care system Lifestyle choices to maximize health Discrimination in employment or insurance Woven throughout the text are stories from more than 100 survivors and parents. Authors Keene, Hobbie, and Ruccione are experts in the field of childhood cancer. Keene is the mother of a survivor of childhood leukemia and the author of several books including Childhood Leukemia, Childhood Cancer, Educating the Child with Cancer, and Chemo, Craziness & Comfort. Hobbie is Associate Director of the Cancer Survivorship Program at Children's Hospital of Philadelphia. Ruccione is Co-Director of the HOPE (Hematology-Oncology Psychosocial and Education) Program in the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles. |
| acute myeloid leukemia questions and answers: Cancer and Aging M. Extermann, 2013-01-18 Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners. |
| acute myeloid leukemia questions and answers: Blood and Marrow Stem Cell Transplantation Marie Bakitas Whedon, Debra Wujcik, 1997 Nursing |
| acute myeloid leukemia questions and answers: Haematology Nursing Marvelle Brown, Tracey Cutler, 2012-03-06 Haematology Nursing is a comprehensive handbook, with a nursing focus, on the care and management of patients with haematological disorders. Divided into four sections, the first provides an introduction to haematology, looking at haemopoiesis, immunology and genetics. Section Two covers non-malignant haematology, including anaemia, haemoglobinopathies and haemochromatosis. Section Three explores the pathophysiology, care and management of myeloproliferative and lymphoproliferative disorders, including leukaemia, myeloma, and lymphoma. The final section provides information on various nursing care interventions, including blood transfusion, venous access devices, and palliative care. Aimed principally at nurses working in a variety of settings including haematology/oncology wards, medical/haematology wards, specialist bone marrow transplant centres, and community settings, Haematology Nursing is an essential and much-needed reference guide. |
| acute myeloid leukemia questions and answers: Life After Suicide Jennifer Ashton, 2019-05-07 From the chief medical correspondent of ABC News, an eloquent, heartbreaking, yet hopeful memoir of surviving the suicide of a loved one, examining this dangerous epidemic and offering first-hand knowledge and advice to help family and friends find peace. Jennifer Ashton, M.D., has witnessed firsthand the impact of a loved one’s suicide. When her ex-husband killed himself soon after their divorce, her world—and that of her children—was shattered. Though she held a very public position with one of the world’s largest media companies, she was hesitant to speak about the personal trauma that she and her family experienced following his death. A woman who addresses the public regularly on intimate health topics, she was uncertain of revealing her devastating loss—the most painful thing she’d ever experienced. But with the high-profile suicides of Kate Spade and Anthony Bourdain, Dr. Ashton recognized the importance of talking about her experience and the power of giving voice to her grief. She shared her story with her Good Morning America family on air—an honest, heartbreaking revelation that provided comfort and solace to others, like her and her family, who have been left behind. In Life After Suicide, she opens up completely for the first time, hoping that her experience and words can inspire those faced with the unthinkable to persevere. Part memoir and part comforting guide that incorporates the latest insights from researchers and health professionals, Life After Suicide is both a call to arms against this dangerous, devastating epidemic, and an affecting story of personal grief and loss. In addition, Dr. Ashton includes stories from others who have survived the death of a loved one by their own hand, showing how they survived the unthinkable and demonstrating the vital roles that conversation and community play in recovering from the suicide of a loved one. The end result is a raw and revealing exploration of a subject that’s been taboo for far too long, providing support, information, and comfort for those attempting to make sense of their loss and find a way to heal. |
| acute myeloid leukemia questions and answers: What You Need to Know about Leukemia , 1994 |
| acute myeloid leukemia questions and answers: Minimal Residual Disease in Acute Leukemia B. Löwenberg, A. Hagenbeek, 1984-01-31 The objective of the treatment of acute leukemia involves the eradication of all neoplastic cells, including the last one. Ideally, treatment should be controlled by monitoring cell kill. If the last cells could be discovered and their biological properties be determined, the qualitative and quantitative effects of treatment should be directly evaluable. This should ultimately permit a calculated tumor cell reduction thereby avoiding overtreatment and excessive toxicity and thus providing a basis for individualized antileukemic treatment. In recent years several new developments have contributed to the selective discovery of minimal numbers of leukemic cells which are hidden among the normal cells in the marrow cavities. These methods are the first steps to the realization of the therapeutic goals indicated above. They include the production and ap plication of monoclonal antibodies against differentiation antigens on the cell sur face, the use of pulse cytophotometry - and cell sorter techniques, the employment of cytogenetics, the development of culture techniques for selective growth of precursor cells and several others. These methodologies offer prospects for refined diagnosis and, as far as the elimination of leukemic cells is concerned, the further development of autologous bone marrow transplantation. Eliminating tumor cells from autologous grafts requires the detailed knowledge of the cellular inter relationships within the neoplasm so that the neoplastic cells responsible for tumor propagation are specifically removed. Recognition and characterization of the clonogenic cells of the neoplasm should then lead to determining their sensitivity to the therapeutic agents which are clinically applied. |
| acute myeloid leukemia questions and answers: Robbins and Cotran Review of Pathology Edward C. Klatt, MD, Vinay Kumar, 2014-09-26 Effectively master the most important principles and facts in pathology with this easy-to-use new edition of Robbins and Cotran Review of Pathology. More than 1,100 questions-reviewed and updated to reflect the new content in the parent text-reinforce the fundamentals of gross and microscopic pathology as well as the latest findings in molecular biology and genetics. This review book of multiple choice questions and answers, companion to Robbins and Cotran Pathologic Basis of Disease 9th Edition and Robbins Basic Pathology, 9th Edition, is the ideal study tool for coursework, self-assessment, and examinations, including the USMLE Step 1 examination in pathology. Access to this product, which may be at the discretion of your institution, is up to 3 years of online and perpetual offline access. Elsevier reserves the right to restrict or remove access due to changes in product portfolio or other market conditions. Develop a thorough, clinically relevant understanding of pathology through clinical vignette-style questions emphasizing problem solving over rote memorization. Single-best-answer and extended-matching formats reflect levels of difficulty that prepare you for examinations. Efficiently review a wide spectrum of topics with page references and a parallel organization to both Robbins and Cotran Pathologic Basis of Disease and Robbins Basic Pathology, making additional information easy to locate. Reinforce your understanding of key content with answers and detailed explanations for every question at the end of each chapter. Enhance your understanding of pathophysiology and integrate pathology with other medical disciplines by examining correlative laboratory, radiologic, and physical diagnostic data. Visualize key pathologic concepts and conditions and test your diagnostic skills with over 1,100 full-color images. Challenge your knowledge with a final comprehensive exam of 50 USMLE-style questions covering random topics. Features new questions that reflect today's hot topics in pathology, keeping you up to date. Includes many new illustrations to enhance visual guidance. Uses a new chapter arrangement to conform to the new Table of Contents in Robbins and Cotran Pathologic Basis of Disease, 8th Edition, for easier cross referencing. |
| acute myeloid leukemia questions and answers: The Ultimate OCN Exam Practice Questions and Exam Prep Toolkit Doris Henley Fort, The field of oncology nursing is one of the most challenging and rewarding specialties in healthcare. As an oncology nurse, you provide critical care, support, and education to patients and their families as they navigate the complex journey of cancer treatment. The Oncology Certified Nurse (OCN) certification is a testament to your expertise and commitment to excellence in this vital field. I created The Ultimate OCN Exam Practice Questions and Exam Prep Toolkit to support you on your path to becoming an OCN-certified professional. My goal is to provide you with a comprehensive, all-in-one resource that not only covers the breadth of exam topics but also equips you with practical tools and strategies to succeed. In this book, you will find: Detailed Study Guide: Each chapter delves into essential topics, from cancer biology and treatment modalities to symptom management and patient care. The content is designed to build a strong foundation of knowledge, ensuring you are well-prepared for every aspect of the exam. Extensive Practice Question Bank: With over 800 practice questions, this book offers ample opportunities to test your understanding and apply your knowledge. Detailed rationales for each question help reinforce learning and clarify complex concepts. Interactive Study Planner and Progress Tracker: These tools allow you to create a personalized study schedule, set achievable goals, and monitor your progress. Staying organized and on track is key to effective exam preparation. Expert Tips and Strategies: Insights from OCN-certified professionals provide valuable guidance on study techniques, exam-day strategies, and maintaining a healthy balance between studying and personal life. Their personal anecdotes and motivational advice will keep you inspired and focused. As you embark on your journey to becoming OCN-certified, remember that this is not just an academic pursuit but a step toward enhancing the care you provide to your patients. Your dedication to professional growth and excellence in oncology nursing makes a significant difference in the lives of those you serve. I hope this book serves as a valuable resource, helping you achieve your certification goals and furthering your impact as a skilled and compassionate oncology nurse. Good luck, and thank you for your commitment to advancing the field of oncology nursing. |
| acute myeloid leukemia questions and answers: Toxicological Profile for Pyrethrins and Pyrethroids , 2003 |
| acute myeloid leukemia questions and answers: Oxford Handbook of Oncology Jim Cassidy, Donald Bissett, Roy Archibald Joseph Spence, Gareth Morris-Stiff, Miranda Payne, 2015 This practical guide to clinical consultation in oncology has been extensively revised and updated. It reflects recent advances in oncology with particular emphasis on new therapies and the emergence of immunotherapy as a real modality. |
| acute myeloid leukemia questions and answers: Application Of Nursing Process and Nursing Diagnosis Marilynn E Doenges, Mary Frances Moorhouse, 2012-12-07 When you understand the whys of each step the nursing process, it’s easier easy to understand how to apply them in the real world in which you will practice. Take an interactive, step-by-step approach to developing the diagnostic reasoning and problem-solving skills you need to think like a nurse with the resources you’ll find in this unique workbook style text. |
| acute myeloid leukemia questions and answers: Histiocytic Disorders Oussama Abla, Gritta Janka, 2017-11-17 This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults. |
| acute myeloid leukemia questions and answers: Immunotherapies for Acute Myeloid Leukemia Jochen Greiner, 2020-12-02 The efficacy of immunotherapeutic approaches in the treatment of different cancer types is becoming increasingly obvious, and immunotherapies in cancer treatment have experienced a significant breakthrough in the last few years. Immunotherapy encompasses several diverse treatment approaches, each of which has a distinct mechanism of action, and all of which are designed to boost or restore immune function in some manner. Consequently, T cell activating immunotherapeutic approaches like immune checkpoint inhibition, chimeric antigen receptor T cells (CARs), or bi-specific T cell activating antibodies are becoming increasingly important treatment strategies in different solid tumor types as well as in hematological malignancies. T cell responses against malignant cells play a major role in maintaining remission and prolonging overall survival in patients after allogeneic stem cell transplantation and donor lymphocyte infusions (DLI) due to the graft-versus-leukemia effect. In acute myeloid leukemia (AML) after intensive chemotherapy, most patients achieve complete remission; however, the overall survival for all AML patients, especially in elderly patients, is still relatively low. Immunotherapeutic approaches for AML patients might be options to reduce the relapse rate and improve overall survival. This Special Issue will focus on immunotherapeutic approaches in AML in established therapies, like the allogeneic stem cell transplantation including new concepts improving the graft-versus-leukemia effect, but also on new efforts to improve immune responses like adoptive T cell transfer, immune checkpoint inhibition, bi-specific antibodies, and CAR-T-cell approaches. |
| acute myeloid leukemia questions and answers: When Blood Breaks Down Mikkael A. Sekeres, 2020-04-21 A leading cancer specialist tells the compelling stories of three adult leukemia patients, shedding new light on the disease itself and the drugs developed to treat it When you are told that you have leukemia, your world stops. Your brain can’t function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together. Sekeres, who writes regularly for the “Well” section of The New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family’s wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimate conversations between Sekeres and his patients, and we watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it—describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia. The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds. |
| acute myeloid leukemia questions and answers: The First Cell Azra Raza, 2019-10-15 With the fascinating scholarship of The Emperor of All Maladies and the deeply personal experience of When Breath Becomes Air, a world-class oncologist examines the current state of cancer and its devastating impact on the individuals it affects -- including herself. In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must. A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear. |
ACUTE Definition & Meaning - Merriam-Webster
The meaning of ACUTE is characterized by sharpness or severity of sudden onset. How to use acute in a sentence. Ways to Be Acute Synonym Discussion of Acute.
ACUTE | English meaning - Cambridge Dictionary
ACUTE definition: 1. If a bad situation is acute, it causes severe problems or damage: 2. An acute pain or illness…. Learn more.
Acute - Definition, Meaning & Synonyms - Vocabulary.com
Use the adjective acute for when you want to describe something as sharp or extremely serious. The word acute is one word; it's not two words, nor does it have anything to do with something …
Acute - definition of acute by The Free Dictionary
Reacting readily to stimuli or impressions; sensitive: His hearing was unusually acute. b. Keenly perceptive or discerning: an acute critic of music; a critic with acute judgment. See Synonyms at …
acute adjective - Definition, pictures, pronunciation and usage …
Definition of acute adjective from the Oxford Advanced Learner's Dictionary. very serious or severe. There is an acute shortage of water. Competition for jobs is acute. The scandal was an acute …
What is Acute, Subacute and Chronic? - Healthhype
Jan 14, 2010 · Acute is the medical term to describe the nature of a disease, sign, symptom or condition. It refers to an illness that is of a sudden onset or of a short duration. Acute can also be …
Meaning of acute – Learner’s Dictionary - Cambridge Dictionary
ACUTE definition: 1. An acute problem or negative feeling is extreme: 2. An acute angle is less than 90 degrees. 3…. Learn more.
ACUTE - Definition & Translations | Collins English Dictionary
You can use acute to indicate that an undesirable situation or feeling is very severe or intense. 2. An acute illness is one that becomes severe very quickly but does not last very long.
ACUTE Definition & Meaning | Dictionary.com
Acute definition: sharp or severe in effect; intense.. See examples of ACUTE used in a sentence.
ACUTE | definition in the Cambridge English Dictionary
ACUTE meaning: 1. If a bad situation is acute, it causes severe problems or damage: 2. An acute pain or illness…. Learn more.
ACUTE Definition & Meaning - Merriam-Webster
The meaning of ACUTE is characterized by sharpness or severity of sudden onset. How to use acute in a sentence. Ways to Be Acute Synonym Discussion of Acute.
ACUTE | English meaning - Cambridge Dictionary
ACUTE definition: 1. If a bad situation is acute, it causes severe problems or damage: 2. An acute pain or illness…. Learn more.
Acute - Definition, Meaning & Synonyms - Vocabulary.com
Use the adjective acute for when you want to describe something as sharp or extremely serious. The word acute is one word; it's …
Acute - definition of acute by The Free Dictionary
Reacting readily to stimuli or impressions; sensitive: His hearing was unusually acute. b. Keenly perceptive or discerning: an acute critic of music; a critic with acute …
acute adjective - Definition, pictures, pronunciation and usag…
Definition of acute adjective from the Oxford Advanced Learner's Dictionary. very serious or severe. There is an acute shortage of water. Competition for jobs is acute. The …
