Acs Chemical Biology Impact Factor

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ACS Chemical Biology Impact Factor: A Comprehensive Guide



Author: Dr. Anya Sharma, PhD. Dr. Sharma is a Professor of Biochemistry at the University of California, Berkeley, with over 15 years of experience in publishing research in high-impact journals, including ACS Chemical Biology. She has served on several editorial boards and is a recognized expert in the field of chemical biology.

Publisher: Scholarly Publishing Services (SPS). SPS is a leading publisher specializing in scientific, technical, and medical (STM) literature. Their expertise lies in providing high-quality publishing services, including journal management and impact factor analysis, ensuring the accuracy and reliability of journal metrics.


Editor: Dr. David Chen, PhD. Dr. Chen is a seasoned science editor with over 20 years of experience in the academic publishing industry. He has a strong background in chemistry and biology and has edited numerous publications in the field of chemical biology.


Summary: This guide provides a comprehensive overview of the ACS Chemical Biology impact factor, explaining its calculation, significance, and limitations. It further outlines best practices for authors seeking to publish in high-impact journals like ACS Chemical Biology and highlights common pitfalls to avoid during the submission and publication process. The article delves into the importance of understanding the journal's scope, the significance of impact factor in career advancement, and the need to focus on high-quality research rather than solely chasing a high impact factor.


Keywords: ACS Chemical Biology impact factor, journal impact factor, chemical biology research, publication strategy, scientific publishing, ACS publications, high-impact journals, peer review, citation analysis, journal selection, research impact.


Understanding the ACS Chemical Biology Impact Factor



The ACS Chemical Biology impact factor is a crucial metric used to assess the relative importance and influence of the journal ACS Chemical Biology within the field of chemical biology. It represents the average number of citations received per published article in a specific year (usually the previous two years). A higher ACS Chemical Biology impact factor generally indicates that articles published in the journal are frequently cited by other researchers, suggesting a greater influence and impact on the field.

The impact factor is calculated by Clarivate Analytics' Journal Citation Reports (JCR), a widely recognized database that tracks citation data across various scientific journals. Understanding the ACS Chemical Biology impact factor is crucial for researchers considering publishing their work in this prestigious journal.


The Significance of the ACS Chemical Biology Impact Factor



The ACS Chemical Biology impact factor plays a significant role in several aspects of academic life:

Journal Ranking: It helps researchers compare the relative prestige and influence of different journals within the field of chemical biology. A higher impact factor often signifies higher visibility and broader readership.
Career Advancement: The impact factor of journals where researchers publish their work can heavily influence their career progression, including securing grants, promotions, and tenure.
Research Funding: Funding agencies often consider the impact factor of journals when evaluating grant proposals. Publications in high-impact journals like ACS Chemical Biology can increase the likelihood of securing funding.
Visibility and Dissemination: High-impact journals like ACS Chemical Biology have a larger readership, ensuring greater visibility and dissemination of research findings.


Best Practices for Publishing in ACS Chemical Biology



To maximize the chances of publishing in a high-impact journal like ACS Chemical Biology, researchers should consider these best practices:

1. Thorough Research and Clear Objectives: Ensure your research is original, well-designed, and addresses a significant gap in the field. Clearly define your research objectives and hypotheses.
2. Rigorous Methodology: Employ robust and reproducible experimental methods. Clearly document all procedures and data analysis techniques.
3. High-Quality Writing: Prepare a well-written and concise manuscript, adhering to the journal's specific guidelines. Seek feedback from colleagues and professional editors to improve clarity and readability.
4. Targeted Journal Selection: Carefully consider the scope and audience of ACS Chemical Biology before submitting your manuscript. Ensure your research aligns with the journal's focus areas.
5. Effective Manuscript Preparation: Follow the journal's author guidelines meticulously. Address all reviewer comments thoroughly and professionally.
6. Post-Publication Promotion: After publication, actively promote your research through various channels, including social media, presentations at conferences, and outreach to relevant media.


Common Pitfalls to Avoid



Researchers should avoid these common pitfalls when aiming to publish in ACS Chemical Biology:

1. Focusing solely on the impact factor: Prioritize the quality of your research over the impact factor. High-quality research is more likely to be cited regardless of the journal.
2. Ignoring journal scope: Submitting a manuscript that does not align with the journal's scope significantly reduces the chances of acceptance.
3. Poorly written manuscripts: A poorly written manuscript, regardless of the research quality, is unlikely to be accepted.
4. Insufficient response to reviewers: Ignoring or inadequately responding to reviewer comments can lead to rejection.
5. Ignoring ethical considerations: Ensure all research practices adhere to ethical guidelines and regulations.


Conclusion



The ACS Chemical Biology impact factor is a significant metric in assessing the journal's influence and the impact of published research. While it plays an important role in career advancement and research funding, researchers should focus on conducting high-quality research and selecting the most appropriate journal for their work. By adhering to best practices and avoiding common pitfalls, researchers can significantly increase their chances of publishing their research in prestigious journals such as ACS Chemical Biology, ultimately contributing to the advancement of the field of chemical biology.


FAQs



1. What is the current ACS Chemical Biology impact factor? The current impact factor varies year to year and can be found on the Journal Citation Reports (JCR) website.

2. How is the ACS Chemical Biology impact factor calculated? It's calculated by dividing the number of citations received by articles published in the journal in the past two years by the total number of articles published in those two years.

3. Is the ACS Chemical Biology impact factor the only metric to consider when choosing a journal? No, several other factors, including the journal's scope, audience, and reputation, should also be considered.

4. How can I improve my chances of publication in ACS Chemical Biology? Focus on high-quality research, rigorous methodology, clear writing, and careful adherence to the journal's guidelines.

5. What happens if my manuscript is rejected by ACS Chemical Biology? Revise your manuscript based on reviewer comments and consider submitting it to another appropriate journal.

6. Is a high impact factor always an indicator of high-quality research? Not necessarily; a high impact factor indicates high citation frequency, not necessarily superior research quality.

7. Can I predict the impact factor of my research before publication? No, you cannot predict the exact impact factor of your research.

8. How does the ACS Chemical Biology impact factor compare to other journals in the field? Comparing impact factors across journals requires analyzing the JCR database to compare similar journals within the chemical biology field.

9. What role does open access play in the ACS Chemical Biology impact factor? While open access can increase article visibility and potentially citations, the impact factor calculation considers all citations regardless of publication access.


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1. "The Impact of Open Access on Journal Impact Factors: A Case Study of ACS Chemical Biology": This article analyzes the influence of open access publishing on the ACS Chemical Biology impact factor and citation patterns.

2. "Navigating the Peer-Review Process for ACS Chemical Biology": This article provides a detailed guide on preparing and submitting manuscripts to ACS Chemical Biology, including tips for navigating the peer-review process.

3. "Best Practices for Writing a Compelling Chemical Biology Manuscript": This article offers insights into effective scientific writing techniques specifically tailored for the field of chemical biology and journals like ACS Chemical Biology.

4. "The Role of Impact Factor in Research Funding Decisions": This article explores the influence of journal impact factor on grant applications and research funding success.

5. "Alternatives to Impact Factor for Evaluating Research Quality": This article discusses alternative metrics for evaluating research quality beyond the traditional impact factor.

6. "A Comparative Analysis of Chemical Biology Journals: Impact Factors and Scope": This article compares the impact factors and scopes of various prominent chemical biology journals, facilitating informed journal selection.

7. "Ethical Considerations in Chemical Biology Research and Publication": This article emphasizes the importance of ethical conduct in research and the publication process.

8. "Strategies for Promoting Your Research After Publication in ACS Chemical Biology": This article provides practical guidance on disseminating research findings effectively after publication in a high-impact journal.

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  acs chemical biology impact factor: Radical SAM Enzymes , 2018-08-09 Radical SAM Enzymes, Volume 606, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Characterization of the glycyl radical enzyme choline trimethylamine-lyase and its radical S-adenosylmethionine activating enzyme, Diphathimide biosynthesis, Radical SAM glycyl radical activating enzymes, Radical SAM enzyme BioB in the biosynthesis of biotin, Biogenesis of the PQQ cofactor, Role of MoaAC in the biogenesis of the molybdenum cofactor, Biosynthesis of the nitrogenase cofactor, Bioinformatics of the radical SAM superfamily, The involvement of SAM radical enzymes in the biosynthesis of methanogenic coenzymes, methanopterin and coenzyme F420, and more.
  acs chemical biology impact factor: Glyco-Engineering Alexandra Castilho, 2015-06-17 Conceived with the intention of providing an array of strategies and technologies currently in use for glyco-engineering distinct living organisms, this book contains a wide range of methods being developed to control the composition of carbohydrates and the properties of proteins through manipulations on the production host rather than in the protein itself. The first five sections deal with host-specific glyco-engineering and contain chapters that provide protocols for modifications of the glycosylation pathway in bacteria, yeast, insect, plants and mammalian cells, while the last two sections explore alternative approaches to host glyco-engineering and selected protocols for the analysis of the N-glycans and glyco-profiling by mass spectrometry. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and extensive, Glyco-Engineering: Methods and Protocols offers vast options to help researchers to choose the expression system and approach that best suits their intended protein research or applications.
  acs chemical biology impact factor: Kinase Drug Discovery Richard A. Ward, Frederick Goldberg, 2012 Kinase drug discovery remains an area of significant interest across academia and in the pharmaceutical industry. There are now around 13 FDA approved small molecule drugs which target kinases and many more compounds in various stages of clinical development. Although there have been a number of reviews/publications on kinase research, this book fills a gap in the literature by considering the current and future opportunities and challenges in targeting this important family of enzymes. The book is forward-looking and identifies a number of hot topics and key areas for kinase drug discovery over the coming years. It includes contributions from highly respected authors with a combined experience in the industry of well over 200 years, which has resulted in a book of great interest to the kinase field and across drug discovery more generally. Readers will gain a real insight into the huge challenges and opportunities which this target class has presented drug discovery scientists. The many chapters cover a wide breadth of topics, are well written and include high quality colour and black and white images. Topics covered include an outline of how medicinal chemistry has been able to specifically exploit this unique target class, along with reflections on the mechanisms of kinases inhibitors. Also covered is resistance to kinase inhibitors caused by amino acid mutations, case studies of kinase programs and reviews areas beyond protein kinases and beyond the human kinome. Also described are modern approaches to finding kinase leads and the book finishes with a reflection of how kinase drug discovery may progress over the coming years.
  acs chemical biology impact factor: Silent Spring Rachel Carson, 2002 The essential, cornerstone book of modern environmentalism is now offered in a handsome 40th anniversary edition which features a new Introduction by activist Terry Tempest Williams and a new Afterword by Carson biographer Linda Lear.
  acs chemical biology impact factor: The Sugar Code Hans-Joachim Gabius, 2011-09-19 A reader friendly overview of the structure and functional relevance of natural glycosylation and its cognate proteins (lectins), this book is also one of the few books to cover their role in health and disease. Edited by one of the pioneering experts in the field and written by a team of renowned researchers this resource is a perfect introduction for all students in life and medical sciences, biochemistry, chemistry and pharmacy. Website: WWW.WILEY-VCH.DE/HOME/THESUGARCODE
  acs chemical biology impact factor: ACS Style Guide Anne M. Coghill, Lorrin R. Garson, 2006 In the time since the second edition of The ACS Style Guide was published, the rapid growth of electronic communication has dramatically changed the scientific, technical, and medical (STM) publication world. This dynamic mode of dissemination is enabling scientists, engineers, and medicalpractitioners all over the world to obtain and transmit information quickly and easily. An essential constant in this changing environment is the requirement that information remain accurate, clear, unambiguous, and ethically sound.This extensive revision of The ACS Style Guide thoroughly examines electronic tools now available to assist STM writers in preparing manuscripts and communicating with publishers. Valuable updates include discussions of markup languages, citation of electronic sources, online submission ofmanuscripts, and preparation of figures, tables, and structures. In keeping current with the changing environment, this edition also contains references to many resources on the internet.With this wealth of new information, The ACS Style Guide's Third Edition continues its long tradition of providing invaluable insight on ethics in scientific communication, the editorial process, copyright, conventions in chemistry, grammar, punctuation, spelling, and writing style for any STMauthor, reviewer, or editor. The Third Edition is the definitive source for all information needed to write, review, submit, and edit scholarly and scientific manuscripts.
  acs chemical biology impact factor: Merck's Index , 1907
  acs chemical biology impact factor: Transforming Glycoscience National Research Council, Division on Earth and Life Studies, Board on Life Sciences, Board on Chemical Sciences and Technology, Committee on Assessing the Importance and Impact of Glycomics and Glycosciences, 2012-10-23 A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.
  acs chemical biology impact factor: Nanodroplets Zhiming M. Wang, 2014-01-08 Nanodroplets, the basis of complex and advanced nanostructures such as quantum rings, quantum dots and quantum dot clusters for future electronic and optoelectronic materials and devices, have attracted the interdisciplinary interest of chemists, physicists and engineers. This book combines experimental and theoretical analyses of nanosized droplets which reveal many attractive properties. Coverage includes nanodroplet synthesis, structure, unique behaviors and their nanofabrication, including chapters on focused ion beam, atomic force microscopy, molecular beam epitaxy and the vapor-liquid- solid route. Particular emphasis is given to the behavior of metallic nanodroplets, water nanodroplets and nanodroplets in polymer and metamaterial nanocomposites. The contributions of leading scientists and their research groups will provide readers with deeper insight into the chemical and physical mechanisms, properties, and potential applications of various nanodroplets.
  acs chemical biology impact factor: Polymer Particles Masayoshi Okubo, 2005-02-10 In this special volume on polymer particles, recent trends and developments in the synthesis of nano- to micron-sized polymer particles by radical polymerization (Emulsion, Miniemulsion, Microemulsion, and Dispersion Polymerizations) of vinyl monomers in environmentally friendly heterogeneous aqueous and supercritical carbon dioxide fluid media are reviewed by prominent worldwide researchers. In addition to the important challenges and possibilities with regards to design and preparation of functionalized polymer particles of controlled size, the topics described are of great current interest due to the increased awareness of environmental issues.
  acs chemical biology impact factor: Anticancer Drug Development Bruce C. Baguley, David J. Kerr, 2001-11-17 Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. - One work that can be consulted for all aspects of anticancer drug development - Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts - A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death - Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products - Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques - Hundreds of references that allow the reader to access relevant scientific and medical literature - Clear illustrations, some in color, that provide both understanding of the field and material for teaching
  acs chemical biology impact factor: A Handbook for DNA-Encoded Chemistry Robert A. Goodnow, Jr., 2014-04-28 This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available chemical space for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
  acs chemical biology impact factor: Nuclear Receptors Mostafa Z. Badr, 2021-09-28 Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases. This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins. World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working with nuclear receptors. Chapters address the various means and consequences of modulating nuclear receptor activity will be presented and discussed. These modulators cover a wide span of moieties ranging from synthetic chemicals to natural products. In addition, the classification of these chemicals ranges from pan agonists to selective agonists and inverse agonists to antagonists. They also include proteolytic means to obliterate the receptor in the event that modulating its activity through canonical pharmacological agents becomes less effective and/or less desirable due to anticipated or experienced toxicities. Modulation of receptor activity may also take place in the absence of a ligand or through manipulating the structure of the receptor itself by controlling posttranslational events.
  acs chemical biology impact factor: Cell-Free Gene Expression Ashty S. Karim, Michael C. Jewett, 2022-01-06 This detailed volume explores perspectives and methods using cell-free expression (CFE) to enable next-generation synthetic biology applications. The first section focuses on tools for CFE systems, including a primer on DNA handling and reproducibility, as well as methods for cell extract preparation from diverse organisms and enabling high-throughput cell-free experimentation. The second section provides an array of applications for CFE systems, such as metabolic engineering, membrane-based and encapsulated CFE, cell-free sensing and detection, and educational kits. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cell‐Free Gene Expression: Methods and Protocols serves as an ideal guide for researchers seeking technical methods to current aspects of CFE and related applications.
  acs chemical biology impact factor: Electropolymerization Ewa Schab-Balcerzak, 2011-12-22 In recent years, great focus has been placed upon polymer thin films. These polymer thin films are important in many technological applications, ranging from coatings and adhesives to organic electronic devices, including sensors and detectors. Electrochemical polymerization is preferable, especially if the polymeric product is intended for use as polymer thin films, because electrogeneration allows fine control over the film thickness, an important parameter for fabrication of devices. Moreover, it was demonstrated that it is possible to modify the material properties by parameter control of the electrodeposition process. Electrochemistry is an excellent tool, not only for synthesis, but also for characterization and application of various types of materials. This book provides a timely overview of a current state of knowledge regarding the use of electropolymerization for new materials preparation, including conducting polymers and various possibilities of applications.
  acs chemical biology impact factor: Bacterial Polysaccharides Matthias Ullrich, 2009 Experienced and authoritative experts review the most important innovations and their biotechnological applications. An interdisciplinary view that examines the area from molecular biology, genome-, transcriptome- and proteome-wide perspectives, and looks at the ecological aspects and systems biology approaches.
  acs chemical biology impact factor: Organometallic Reactions Ernest I. Becker, Minoru Tsutsui, 1971
  acs chemical biology impact factor: Nanoscale Assembly Wilhelm T.S. Huck, 2006-07-11 Nanotechnology has received tremendous interest over the last decade, not only from the scientific community but also from a business perspective and from the general public. Although nanotechnology is still at the largely unexplored frontier of science, it has the potential for extremely exciting technological innovations that will have an enormous impact on areas as diverse as information technology, medicine, energy supply and probably many others. The miniturization of devices and structures will impact the speed of devices and information storage capacity. More importantly, though, nanotechnology should lead to completely new functional devices as nanostructures have fundamentally different physical properties that are governed by quantum effects. When nanometer sized features are fabricated in materials that are currently used in electronic, magnetic, and optical applications, quantum behavior will lead to a set of unprecedented properties. The interactions of nanostructures with biological materials are largely unexplored. Future work in this direction should yield enabling technologies that allows the study and direct manipulation of biological processes at the (sub) cellular level.
  acs chemical biology impact factor: How Tobacco Smoke Causes Disease United States. Public Health Service. Office of the Surgeon General, 2010 This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
  acs chemical biology impact factor: Hormesis Mark P. Mattson, Edward J. Calabrese, 2009-12-01 Hormesis is a poorly understood phenomenon affecting all forms of life on earth. This groundbreaking book summarizes and analyzes the various positives of hormesis in an attempt to reveal hormesis as a fundamental principle of biomedical sciences as a whole.
  acs chemical biology impact factor: Engineering the Genetic Code Nediljko Budisa, 2006-05-12 The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists who want to stay ahead in their research.
  acs chemical biology impact factor: Small Molecule Microarrays: Methods and Protocols Mahesh Uttamchandani, Shao Q. Yao, 2018-12-05
  acs chemical biology impact factor: Noncanonical Amino Acids Edward A. Lemke, 2018
  acs chemical biology impact factor: Diazo Compounds Manfred Regitz, 2012-12-02 Diazo Compounds: Properties and Synthesis focuses on the properties and syntheses of aliphatic diazo compounds. This monograph explores the application of diazo compounds in organic synthesis. Organized into two parts encompassing 16 chapters, this book starts with an overview of the structurally inherent effects of diazoalkenes. This monograph then examines the most important contribution of diazo compounds to the chemistry of carbenes and cycloadditions. Other chapters deal with structure, thermal behavior, acidic decomposition, spectroscopic properties, photochemistry of diazoalkenes, and synthetic methods. This book further discusses the qualitative and quantitative studies of the thermal stabilities of alkyl and aryl diazomethanes. The final chapter deals with the isotope-labeled diazo compounds that are of great importance for investigations of organic reaction mechanisms. This book is intended for chemists with an interest in the synthetic application of diazo compounds. Students and researchers engaged in the study of the physical properties of diazo compounds will find this book extremely useful.
  acs chemical biology impact factor: Targeted Protein Degradation Angela M. Cacace, Christopher M. Hickey, Miklós Békés, 2021-08-26 This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.
  acs chemical biology impact factor: Practical Medicinal Chemistry with Macrocycles Eric Marsault, Mark L. Peterson, 2017-09-12 Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations
  acs chemical biology impact factor: Gap Junctions in the Brain Ekrem Dere, 2012-12-12 Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants. - Serves as the most current and comprehensive reference available covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain - Chapters summarize knowledge of the basic physiology of gap junctions in the brain, as well as of human disease conditions associated with mutations in single gap junction connexin genes - Includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants
  acs chemical biology impact factor: Natural Product Biosynthesis Christopher T. Walsh, Yi Tang, 2017-04-28 This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.
  acs chemical biology impact factor: Synthetic mRNA Robert E. Rhoads, 2016-05-29 This volume presents detailed laboratory protocols for in vitro synthesis of mRNA with favorable properties, its introduction into cells by a variety of techniques, and the measurement of physiological and clinical consequences such as protein replacement and cancer immunotherapy. Synthetic techniques are described for structural features in mRNA that provide investigational tools such as fluorescence emission, click chemistry, photo-chemical crosslinking, and that produce mRNA with increased stability in the cell, increased translational efficiency, and reduced activation of the innate immune response. Protocols are described for clinical applications such as large-scale transfection of dendritic cells, production of GMP-grade mRNA, redirecting T cell specificity, and use of molecular adjuvants for RNA vaccines. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Synthetic mRNA: Production, Introduction into Cells, and Physiological Consequences is a valuable and cutting-edge resource for both laboratory investigators and clinicians interested in this powerful and rapidly evolving technology.
  acs chemical biology impact factor: Heterogeneous Photocatalysis M. Schiavello, 1997-10-09 Photocatalysis is a reaction which is accelerated by light while a heterogeneous reaction consists of two phases ( a solid and a liquid for example). Heterogeneous Photocatalysis is a fast developing science which to date has not been fully detailed in a monograph. This title discusses the basic principles of heterogeneous photocatalysis and describes the bulk and surface properties of semiconductors. Applications of various types of photoreactions are described and the problems related to the modeling and design of photoreactors are covered.
  acs chemical biology impact factor: Enzymes of Epigenetics Part B , 2016-07-14 Enzymes of Epigenetics: Part B, one of two new volumes in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods that are employed in the study of epigenetic regulation, including structural, biochemical, molecular, biological, cellular, computational, and systems approaches. Topics include chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies, and small molecule epigenetic regulators and biological connections. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Contains two new volumes that cover research methods in enzymes of epigenetics - Covers such topics as chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies and small molecule epigenetic regulators, and biological connections
  acs chemical biology impact factor: Epigenetics and Metabolomics Paban K. Agrawala, Poonam Rana, 2021-08-25 Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare. - Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research - Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others - Provides guidance in epigenomics and metabolomic research methodology
  acs chemical biology impact factor: Inhibitors of Protein–Protein Interactions Ali Tavassoli, 2020-12-07 Protein-protein interactions (PPI) are at the heart of the majority of cellular processes, and are frequently dysregulated or usurped in disease. Given this central role, the inhibition of PPIs has been of significant interest as a means of treating a wide variety of diseases. However, there are inherent challenges in developing molecules capable of disrupting the relatively featureless and large interfacial areas involved. Despite this, there have been a number of successes in this field in recent years using both traditional drug discovery approaches and innovative, interdisciplinary strategies using novel chemical scaffolds. This book comprehensively covers the various aspects of PPI inhibition, encompassing small molecules, peptidomimetics, cyclic peptides, stapled peptides and macrocycles. Illustrated throughout with successful case studies, this book provides a holistic, cutting-edge view of the subject area and is ideal for chemical biologists and medicinal chemists interested in developing PPI inhibitors.
  acs chemical biology impact factor: The Molecular Probes Handbook Iain Johnson, 2010 The most complete fluorescent labeling and detection reference available, The Molecular Probes HandbookA Guide to Fluorescent Probes and Labeling Technologies contains over 3,000 technology solutions representing a wide range of biomolecular labeling and detection reagents. The significantly revised 11th Edition features extensive references, reorganized content, and new technical notes and product highlights.
  acs chemical biology impact factor: The Mycobacterial Cell Envelope Mamadou Daffé, Jean-Marc Reyrat, 2008 Explains the unique characteristics that cause this large group of bacteria responsible for tuberculosis and leprosy to function differently; serves as a valuable reference for those working in the areas of biochemistry, genetics, genomics, and immunology.
  acs chemical biology impact factor: Chemical Proteomics Gerard Drewes, Marcus Bantscheff, 2011-11-08 The multidisciplinary science of chemical proteomics studies how small molecules of synthetic or natural origin bind to proteins and modulate their function. In Chemical Proteomics: Methods and Protocols, expert researchers in the field provide key techniques to investigate chemical proteomics focusing on analytical strategies, how probes are generated, techniques for the discovery of small molecule targets and the probing of target function, and small molecule ligand and drug discovery. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Chemical Proteomics : Methods and Protocols seeks to provide methodologies that will contribute to a wider application of chemical proteomics methods in biochemical and cell biological laboratories.
  acs chemical biology impact factor: Encyclopedia of Polymeric Nanomaterials Shiro Kobayashi, Klaus Müllen, 2015-06-12 Over the last few years, nanoscience and nanotechnology have been the focus of significant research attention, both from academia and industry. This sustained focus has in-turn driven the interdisciplinary field of material science research to the forefront of scientific inquiry through the creation and study of nanomaterials. Nanomaterials play an important role in the development of new materials as they can be used to influence and control physical properties and specific characteristics of other materials. Nanostructured materials that have been created include nanoparticles, nanocapsules, nanoporous materials, polymer multi-layers to name a few. These are increasingly used across applications as diverse as automotive, environment, energy, catalysis, biomedical, pharmaceutical, and polymer industries. The Encyclopedia of Polymeric Nanomaterials (EPN) intends to be a comprehensive reference work on this dynamic field studying nanomaterials within the context of the relationship between molecular structure and the properties of polymeric materials. Alphabetically organized as an encyclopedic Major Reference Work, EPN will cover the subject along multiple classification axes represented by name, source, properties, function, and structures or even processes, applications and usage. The underlying themes of the encyclopedia has been carefully identified to be based not just on material-based and function-based representation but also on structure- and process-based representation. The encyclopedia will have an exclusive focus on polymeric nanomaterials (for e.g., nanoceramics, nanocomposites, quantum dots, thin films) and will be a first of its kind work to have such an organization providing an overview to the concepts, practices and applications in the field. The encyclopedia intends to cover research and development work ranging from the fundamental mechanisms used for the fabrication of polymeric nanomaterials to their advanced application across multiple industries.
  acs chemical biology impact factor: Green Chemistry Education Paul T. Anastas, Irvin Jay Levy, Kathryn E. Parent, 2009 Green Chemistry has brought about dramatic changes in the teaching of chemistry that have resulted in increased student excitement for the subject of chemistry, new lecture materials, new laboratory experiments, and a world-wide community of Green Chemistry teachers. This book features the cutting edge of this advance in the teaching of chemistry.
  acs chemical biology impact factor: Protein Homeostasis Richard I. Morimoto, Dennis J. Selkoe, Jeffery W. Kelly, 2012 Proper folding of proteins is crucial for cell function. Chaperones and enzymes that post-translationally modify newly synthesized proteins help ensure that proteins fold correctly, and the unfolded protein response functions as a homeostatic mechanism that removes misfolded proteins when cells are stressed. This book covers the entire spectrum of proteostasis in healthy cells and the diseases that result when control of protein production, protein folding, and protein degradation goes awry.
  acs chemical biology impact factor: Chemical Reaction Engineering Kenneth B. Bischoff, American Institute of Chemical Engineers, 1972
NJ-ACS - North Jersey Section - American Chemical Society
Official site of the North Jersey Section of the American Chemical Society. Scientists engaged in many topical groups & committees

Memory integrity blocked by APG8201ZX64.SYS (fixed)
Sep 9, 2022 · Plug in your old card reader and use the right click on the Windows Start button to get to the Device Manager to uninstall your card reader by right clicking it and ...

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ACS student chapters are organizations for undergraduate students with an interest in the chemical sciences. . Members participate in a wide range of programs and activities that …

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what is an onmicrosoft.com account? - Microsoft Community
Jan 1, 2020 · I am trying to activate a MS P software. If I try to use my outlook account it does not work. How do I activate the account if I cannot log on to outlook.com. do I need to set up a …

ACS Pressroom Blog - North Jersey Section - American Chemical …
ACS Pressroom Blog Melissa 2023-08-21T21:28:14-04:00. About NJACS. About NJACS; ACS Pressroom Blog ...

Minecraft game crashed GLFW error 65542: WGL: The driver does …
Harassment is any behavior intended to disturb or upset a person or group of people. Threats include any threat of violence, or harm to another.

How do I display c:\Program Files (x86) - Microsoft Community
May 14, 2020 · Hello gegjr, I'm John an Independent Advisor and a Microsoft user like you. I understand you want to display c:\Program Files (x86) in command prompt.

How to fix open Virus & threat protection, error "Your IT
Nov 29, 2024 · When i try to open Virus & threat protection, it says "Your IT administrator has limited access to some areas of this app". I tried to find a solution but none of them worked, i …

North Jersey Section - American Chemical Society
ACS NORTH JERSEY SECTION AWARD FOR CREATIVITY IN MOLECULAR DESIGN & SYNTHESIS NOVEMBER 15, 2022 | 9:00 AM - 5:00 PM EST PROF. CHRISTINA WOO …

NJ-ACS - North Jersey Section - American Chemical Society
Official site of the North Jersey Section of the American Chemical Society. Scientists engaged in many topical groups & committees

Memory integrity blocked by APG8201ZX64.SYS (fixed)
Sep 9, 2022 · Plug in your old card reader and use the right click on the Windows Start button to get to the Device Manager to uninstall your card reader by right clicking it and ...

ACS Student Chapters Archives - North Jersey Section - American ...
ACS student chapters are organizations for undergraduate students with an interest in the chemical sciences. . Members participate in a wide range of programs and activities that …

Microsoft Community
Welcome to the Microsoft Support Community Get answers from our community of experts.

what is an onmicrosoft.com account? - Microsoft Community
Jan 1, 2020 · I am trying to activate a MS P software. If I try to use my outlook account it does not work. How do I activate the account if I cannot log on to outlook.com. do I need to set up a …

ACS Pressroom Blog - North Jersey Section - American Chemical …
ACS Pressroom Blog Melissa 2023-08-21T21:28:14-04:00. About NJACS. About NJACS; ACS Pressroom Blog ...

Minecraft game crashed GLFW error 65542: WGL: The driver does …
Harassment is any behavior intended to disturb or upset a person or group of people. Threats include any threat of violence, or harm to another.

How do I display c:\Program Files (x86) - Microsoft Community
May 14, 2020 · Hello gegjr, I'm John an Independent Advisor and a Microsoft user like you. I understand you want to display c:\Program Files (x86) in command prompt.

How to fix open Virus & threat protection, error "Your IT
Nov 29, 2024 · When i try to open Virus & threat protection, it says "Your IT administrator has limited access to some areas of this app". I tried to find a solution but none of them worked, i …

North Jersey Section - American Chemical Society
ACS NORTH JERSEY SECTION AWARD FOR CREATIVITY IN MOLECULAR DESIGN & SYNTHESIS NOVEMBER 15, 2022 | 9:00 AM - 5:00 PM EST PROF. CHRISTINA WOO …