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| antidepressants study casts doubt: Ordinarily Well Peter D. Kramer, 2016-06-07 Do antidepressants work, or are they glorified dummy pills? How can we tell? In Ordinarily Well, the celebrated psychiatrist and author Peter D. Kramer examines the growing controversy about the popular medications. A practicing doctor who trained as a psychotherapist and worked with pioneers in psychopharmacology, Kramer combines moving accounts of his patients’ dilemmas with an eye-opening history of drug research to cast antidepressants in a new light. Kramer homes in on the moment of clinical decision making: Prescribe or not? What evidence should doctors bring to bear? Using the wide range of reference that readers have come to expect in his books, he traces and critiques the growth of skepticism toward antidepressants. He examines industry-sponsored research, highlighting its shortcomings. He unpacks the “inside baseball” of psychiatry—statistics—and shows how findings can be skewed toward desired conclusions. Kramer never loses sight of patients. He writes with empathy about his clinical encounters over decades as he weighed treatments, analyzed trial results, and observed medications’ influence on his patients’ symptoms, behavior, careers, families, and quality of life. He updates his prior writing about the nature of depression as a destructive illness and the effect of antidepressants on traits like low self-worth. Crucially, he shows how antidepressants act in practice: less often as miracle cures than as useful, and welcome, tools for helping troubled people achieve an underrated goal—becoming ordinarily well. |
| antidepressants study casts doubt: Methods of Behavior Analysis in Neuroscience Jerry J. Buccafusco, 2000-08-29 Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic |
| antidepressants study casts doubt: The Emperor's New Drugs Irving Kirsch, 2010-01-26 Do antidepressants work? Of course -- everyone knows it. Like his colleagues, Irving Kirsch, a researcher and clinical psychologist, for years referred patients to psychiatrists to have their depression treated with drugs before deciding to investigate for himself just how effective the drugs actually were. Over the course of the past fifteen years, however, Kirsch's research -- a thorough analysis of decades of Food and Drug Administration data -- has demonstrated that what everyone knew about antidepressants was wrong. Instead of treating depression with drugs, we've been treating it with suggestion. The Emperor's New Drugs makes an overwhelming case that what had seemed a cornerstone of psychiatric treatment is little more than a faulty consensus. But Kirsch does more than just criticize: he offers a path society can follow so that we stop popping pills and start proper treatment for depression. |
| antidepressants study casts doubt: Depression National Collaborating Centre for Mental Health (Great Britain), Nccmh, 2004 |
| antidepressants study casts doubt: Deadly Medicines and Organised Crime Peter Gotzsche, 2019-08-21 PRESCRIPTION DRUGS ARE THE THIRD LEADING CAUSE OF DEATH AFTER HEART DISEASE AND CANCER. In his latest ground-breaking book, Peter C Gotzsche exposes the pharmaceutical industries and their charade of fraudulent behaviour, both in research and marketing where the morally repugnant disregard for human lives is the norm. He convincingly draws close co |
| antidepressants study casts doubt: Clinical Handbook for the Management of Mood Disorders J. John Mann, Patrick J. McGrath, Steven P. Roose, 2013-05-09 Provides a one-stop evidence-based guide to the management of all types of mood disorders. |
| antidepressants study casts doubt: Essentials of Discursive Psychology Linda M. McMullen, 2021 This guide explains how to conduct a discursive psychology research project. Such research explores how our use of language results in specific beliefs, versions of reality, and social actions. |
| antidepressants study casts doubt: Listening to Prozac Peter D. Kramer, 1997-09-01 The New York Times bestselling examination of the revolutionary antidepressant, with a new introduction and afterword reflecting on Prozac’s legacy and the latest medical research “Peter Kramer is an analyst of exceptional sensitivity and insight. To read his prose on virtually any subject is to be provoked, enthralled, illuminated.” —Joyce Carol Oates When antidepressants like Prozac first became available, Peter D. Kramer prescribed them, only to hear patients say that on medication, they felt different—less ill at ease, more like the person they had always imagined themselves to be. Referencing disciplines from cellular biology to animal ethology, Dr. Kramer worked to explain these reports. The result was Listening to Prozac, a revolutionary book that offered new perspectives on antidepressants, mood disorders, and our understanding of the self—and that became an instant national and international bestseller. In this thirtieth anniversary edition, Dr. Kramer looks back at the influence of his groundbreaking book, traces progress in the relevant sciences, follows trends in the use and public understanding of antidepressants, and assesses potential breakthroughs in the treatment of depression. The new introduction and afterword reinforce and reinvigorate a book that the New York Times called “originally insightful” and “intelligent and informative,” a window on a medicine that is “telling us new things about the chemistry of human character.” |
| antidepressants study casts doubt: Lost Connections Johann Hari, 2020-11-12 THE INTERNATIONAL BESTSELLER: A radically new way of thinking about depression and anxiety 'A book that could actually make us happy' SIMON AMSTELL 'This amazing book will change your life' ELTON JOHN 'One of the most important texts of recent years' BRITISH JOURNAL OF GENERAL PRACTICE 'Brilliant, stimulating, radical' MATT HAIG 'The more people read this book, the better off the world will be' NAOMI KLEIN 'Wonderful' HILLARY CLINTON 'Eye-opening' GUARDIAN 'Brilliant for anyone wanting a better understanding of mental health' ZOE BALL 'A game-changer' DAVINA MCCALL 'Extraordinary' DR MAX PEMBERTON Depression and anxiety are now at epidemic levels. Why? Across the world, scientists have uncovered evidence for nine different causes. Some are in our biology, but most are in the way we are living today. Lost Connections offers a radical new way of thinking about this crisis. It shows that once we understand the real causes, we can begin to turn to pioneering new solutions – ones that offer real hope. |
| antidepressants study casts doubt: International Review of Neurobiology , 1986-12-17 International Review of Neurobiology |
| antidepressants study casts doubt: Neurobiology of Depression Joao Quevedo, Andre F. Carvalho, Carlos A. Zarate, 2019-03-15 Depression is one of the most common mental-health disorders, caused by a variety of genetic, biological, environmental, and psychological factors combined. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission; however, only approximately one third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness, and certain symptomatic clusters may be promising targets for novel therapeutics, such as drug and psychological treatments for the management of the cognitive impairments that can encompass several domains and contribute to psychosocial function, and that can persist for many patients even in periods of symptomatic remission. Neurobiology of Depression synthesizes the basic neurobiology of major depressive disorder with discussion of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing researchers' perspectives and may revolutionize research into depression. The basic foundational understanding of the neurobiology underlying the disorder, as well as the comprehensive summary of the most recent advances in research, combine to aid advanced students and researchers in their understanding of MDD and change the landscape of the management of depression with the development of novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to antidepressants to novel therapeutics Synthesizes discussion of cellular and molecular mechanisms underlying symptoms with clinical aspects of depression for a thorough understanding of the disorder |
| antidepressants study casts doubt: Quality of Life Research Mark Rapley, 2003-04-03 This is the first introductory text to offer a critical overview of the concept of quality of life and the ways in which it is researched. Using an inter-disciplinary approach, the book covers every aspect of the concept and its application. |
| antidepressants study casts doubt: Mood Disorders Eric J. L. Griez, 2005-04-08 Written by an outstanding team of internationally recognised experts, this practical textbook is based on the European Certificate in Anxiety and Mood Disorders. It provides a thorough overview of diagnosis and treatment of mood disorders and analyses the most recent developments and scientific evidence. Covers the most important clinical topics in the field, including symptomatology, natural course and diagnosis Treatment strategies are reviewed in the light of all available empirical evidence Outstanding list of international contributors |
| antidepressants study casts doubt: Studies on the Effectiveness of Antidepressant Drugs Aaron Smith, Elizabeth Traganza, Grace Harrison, 1969 |
| antidepressants study casts doubt: Electroconvulsive and Neuromodulation Therapies Conrad M. Swartz, 2009-03-02 Electroconvulsive therapy (ECT) is a psychiatric treatment involving the induction of a seizure through the transmission of electricity in the brain. Because of exploitation movies and greatly heightened drug company promotional activities ECT was used less frequently in the 1980s and 1990s. Eventually these movies were understood as unrealistic. Now these drugs are increasingly recognized as dangers to body health. Because of recent refinements and a far better scientific understanding of the clinical procedures and mechanisms underpinning ECT, this treatment modality has seen a resurgence in use and widespread appreciation of its safety. This book is the new definitive reference on electroconvulsive and neuromodulation therapies. It comprehensively covers the scientific basis and clinical practice of ECT as well as comparisons between ECT and medication therapies including the new generation of antipsychotic drugs. It also provides readers with administrative perspectives and specific details for the management of this modality in clinical practice. The new forms of nonconvulsive electrical and magnetic brain stimulation therapy are also covered in detail, in a separate section. The chapter authors are leading scholars and clinicians. |
| antidepressants study casts doubt: Manic-Depressive Illness Frederick K. Goodwin, Kay Redfield Jamison, 2007-03-22 The revolution in psychiatry that began in earnest in the 1960s led to dramatic advances in the understanding and treatment of manic-depressive illness. Hailed as the most outstanding book in the biomedical sciences when it was originally published in 1990, Manic-Depressive Illness was the first to survey this massive body of evidence comprehensively and to assess its meaning for both clinician and scientist. It also vividly portrayed the experience of manic-depressive illness from the perspective of patients, their doctors, and researchers. Encompassing an understanding about the illness as Kraeplin conceived of it- about its cyclical course and about the essential unity of its bipolar and recurrent unipolar forms- the book has become the definitive work on the topic, revered by both specialists and nonspecialists alike. Now, in this magnificent second edition, Drs. Frederick Goodwin and Kay Redfield Jamison bring their unique contribution to mental health science into the 21st century. In collaboration with a team of other leading scientists, a collaboration designed to preserve the unified voice of the two authors, they exhaustively review the biological and genetic literature that has dominated the field in recent years and incorporate cutting-edge research conducted since publication of the first edition. They also update their surveys of psychological and epidemiological evidence, as well as that pertaining to diagnostic issues, course, and outcome, and they offer practical guidelines for differential diagnosis and clinical management. The medical treatment of manic and depressive episodes is described, strategies for preventing future episodes are given in detail, and psychotherapeutic issues common in this illness are considered. Special emphasis is given to fostering compliance with medication regimens and treating patients who abuse drugs and alcohol or who pose a risk of suicide. This book, unique in the way that it retains the distinct perspective of its authors while assuring the maximum in-depth coverage of a vastly expanded base of scientific knowledge, will be a valuable and necessary addition to the libraries of psychiatrists and other physicians, psychologists, clinical social workers, neuroscientists, pharmacologists, and the patients and families who live with manic-depressive illness. |
| antidepressants study casts doubt: A Cure for Darkness Alex Riley, 2022-03 A portion of this book was previously published in a different form in 'How a wooden bench in Zimbabwe is starting a revolution in mental health' by Alex Riley in Mosaic in 2018--Copyright page. |
| antidepressants study casts doubt: Clinical Pharmacology in Psychiatry Svein G. Dahl, Lars F. Gram, Steven M. Paul, William Z. Potter, 2012-12-06 The Fourth International Meeting on Clinical Pharmacology in Psychiatry was held in Bethesda, Maryland on 5-8 September 1985 and was dedicated to the memory of Dr. Earl Usdin. Earl was one of the organizers of the three previous meetings held in Chicago (1979), Troms0 (1980), and Odense (1982). During the organization of the fourth meeting Earl became ill and had to relinquish his role as one of the principal organizers. It is safe to conclude that there was no better, or more professional, or more efficient an organizer of scientific meetings in the field of neuropharmacology and psychiatry than Earl U sdin, and it was quite a task for the remaining organizers to fill the void left when he withdrew from this one. Those of us who have organized previous meetings with Earl were struck by how much more difficult our work became without him. This obviously speaks well for his subtle (and at times not so subtle) organizational skills. Nevertheless, in Earl's memory the organizers proceeded to invite a group of internationally renowned neuropsychopharmacologists to address the problem of selectivity in psychotropic drug action and to try to reconcile the amazing advances in basic preclinical neuropsychopharmacology with the problem of clinical specificity encountered by the psychiatrist. |
| antidepressants study casts doubt: Practical Psychopharmacology Joseph F. Goldberg, Stephen M. Stahl, 2021-04-29 A practical guide translating clinical trials findings, across major psychiatric disorders, to devise tailored, evidence-based treatments. |
| antidepressants study casts doubt: Poets on Prozac Richard M. Berlin, 2008-04-30 In this collection of 16 essays, poets discuss psychiatric treatment and their work. Poets on Prozac shatters the notion that madness fuels creativity by giving voice to contemporary poets who have battled myriad psychiatric disorders, including depression, schizophrenia, post-traumatic stress disorder, and substance abuse. The sixteen essays collected here address many provocative questions: Does emotional distress inspire great work? Is artistry enhanced or diminished by mental illness? What effect does substance abuse have on esthetic vision? Do psychoactive medications impinge on ingenuity? Can treatment enhance inherent talents, or does relieving emotional pain shut off the creative process? Featuring examples of each contributor’s poetry before, during, and after treatment, this original and thoughtful collection finally puts to rest the idea that a tortured soul is one’s finest muse. Honorable Mention, 2008 PROSE Award for Best Book in Psychology. “A fascinating collection of 16 essays, as insightful as they are compulsively readable. Each is honest and sharply written, covering a range of issues (depression, anxiety, obsessive-compulsive disorder, psychosis, substance abuse or, in acutely deadpan Andrew Hudgins’s case, “tics, twitches, allergies, tooth-grinding, acid reflux, migraines . . . and shingles”) along with treatment methods, incorporating personal anecdotes and excerpts from poems and journals. . . . Anyone affected by mental illness or intrigued by the question of its role in the arts should find this volume absorbing.” —Publishers Weekly “Berlin has done a marvelous job of showing us how ordinary poets are; the selected poets have shown us that mental illness shares with other experiences a capacity to reveal our humanity.” —Metapsychology |
| antidepressants study casts doubt: My Revision Notes: AQA (A) A2 Psychology Jean-Marc Lawton, 2012-04-13 Get the best grades with My Revision Notes: AQA (A) A2 Psychology. Manage your own revision with step-by-step support from senior examiner Jean-Marc LawtonUse research summaries and evaluation notes to improve your knowledge of key theories and studiesGet the top marks by demonstrating your understanding of the research methods psychologists useImprove your exam skills with self-testing and exam-style questions and answers My Revision Notes will help you prepare for the big day: Plan and pace your revision with My Revision PlannerUse the concise notes to revise the essential informationUse the examiner's tips and summaries to clarify key pointsAvoid making typical mistakes with expert adviceTest yourself with end-of-topic questions and answers and tick off each topic as you complete itPractise your exam skills on exam questions then check your answers onlineGet exam-ready with last-minute quick quizzes at www.therevisionbutton.co.uk/myrevisionnotes |
| antidepressants study casts doubt: The Maudsley Prescribing Guidelines for Mental Health Conditions in Physical Illness Siobhan Gee, David M. Taylor, 2024-10-07 Meet the challenges of mental health prescribing in the physically unwell with this essential guide Treating mental health conditions in physically unwell patients presents unique challenges for clinicians and other practitioners. The efficacy and safety of psychotropic medications is established in physically healthy patients. In physically unwell people, psychotropics can have different outcomes and give rise to serious adverse effects that can complicate or worsen physical health conditions. Many clinicians face difficult decisions about prescribing for mental health conditions in such cases, and reliable information for them is scarce. The Maudsley® Prescribing Guidelines for Mental Health Conditions in Physical Illness meets this urgent need with a comprehensive guide to the safe and effective pharmacological management of mental illness in physically unwell patients. Covering a wide range of physical health conditions and comorbidities, the book makes evidence-based recommendations on pharmacological interventions. It’s an essential resource for any clinical practitioner looking to balance the physical and mental wellbeing of people with concurrent physical and mental health conditions. The Maudsley® Prescribing Guidelines for Mental Health Conditions in Physical Illness readers will also find: Prescribing recommendations for mental health conditions including depression, anxiety, psychosis and bipolar affective disorder Detailed discussion of the consequences for mental health prescribing in physical health conditions such as cardiac disease, diabetes, chronic obstructive pulmonary disease, and many more Treatment of complex and frequently encountered clinical scenarios such as restarting psychotropics after overdose and steroid-induced psychiatric conditions The Maudsley® Prescribing Guidelines for Mental Health Conditions in Physical Illness is an essential reference for all prescribers, clinical pharmacists and nurses who work with patients with comorbid mental and physical illnesses. |
| antidepressants study casts doubt: Manufacturing Depression Gary Greenberg, 2010-02-02 Am I depressed or just unhappy? In the last two decades, antidepressants have become staples of our medicine cabinets—doctors now write 120 million prescriptions annually, at a cost of more than 10 billion dollars. At the same time, depression rates have skyrocketed; twenty percent of Americans are now expected to suffer from it during their lives. Doctors, and drug companies, claim that this convergence is a public health triumph: the recognition and treatment of an under-diagnosed illness. Gary Greenberg, a practicing therapist and longtime depressive, raises a more disturbing possibility: that the disease has been manufactured to suit (and sell) the cure. Greenberg draws on sources ranging from the Bible to current medical journals to show how the idea that unhappiness is an illness has been packaged and sold by brilliant scientists and shrewd marketing experts—and why it has been so successful. Part memoir, part intellectual history, part exposé—including a vivid chronicle of his participation in a clinical antidepressant trial—Manufacturing Depression is an incisive look at an epidemic that has changed the way we have come to think of ourselves. |
| antidepressants study casts doubt: Essential Psychiatry Robin M. Murray, Kenneth S. Kendler, Peter McGuffin, Simon Wessely, David J. Castle, 2008-09-18 This is a major international textbook for psychiatrists and other professionals working in the field of mental healthcare. With contributions from opinion-leaders from around the globe, this book will appeal to those in training as well as to those further along the career path seeking a comprehensive and up-to-date overview of effective clinical practice backed by research evidence. The book is divided into cohesive sections moving from coverage of the tools and skills of the trade, through descriptions of the major psychiatric disorders and on to consider special topics and issues surrounding service organization. The final important section provides a comprehensive review of treatments covering all of the major modalities. Previously established as the Essentials of Postgraduate Psychiatry, this new and completely revised edition is the only book to provide this depth and breadth of coverage in an accessible, yet authoritative manner. |
| antidepressants study casts doubt: Blaming the Brain Elliot Valenstein, 2002-02 In Blaming the Brain Elliott Valenstein exposes the many weaknesses inherent in the scientific arguments supporting the widely accepted theory that biochemical imbalances are the main cause of mental illness. He lays bare the commercial motives of drug companies and their huge stake in expanding their markets. This provocative book will force patients, practitioners, and prescribers alike to rethink the causes of mental illness and the methods by which we treat it. |
| antidepressants study casts doubt: Talking Back to Prozac Peter R. Breggin, Ginger Ross Breggin, 2014-04-01 A psychiatrist takes a critical look at this SSRI and newer medications that are among the most frequently prescribed drugs in America. Prozac. Millions of Americans are on it. And just about everyone else is wondering if they should be on it, too. The claims of the pro‐Prozac chorus are enticing: that it can cure everything from depression (the only disorder for which Prozac was originally approved) to fear of public speaking, PMS, obesity, shyness, migraine, and back pain—with few or no side effects. But is the reality quite different? At what price do we buy Prozac‐induced euphoria and a shiny new personality? Psychiatrist Peter Breggin, MD, and coauthor Ginger Ross Breggin answer these and other crucial questions in Talking Back to Prozac. They explain what Prozac is and how it works, and they take a hard look at the real story behind today’s most controversial drug: The fact that Prozac was tested in trials of four to six weeks in length before receiving FDA approval The difficulty Prozac’s manufacturer had in proving its effectiveness during these tests The information on side effects that the FDA failed to include in its final labeling requirements How Prozac acts as a stimulant not unlike the addictive drugs cocaine and amphetamine The dangers of possible Prozac addiction and abuse The seriousness and frequency of Prozac’s side effects, including agitation, insomnia, nausea, diarrhea, loss of libido, and difficulty reaching orgasm The growing evidence that Prozac can cause violence and suicide The social and workplace implications of using the drug not to cure depression but to change personality and enhance performance Using dramatic case histories as well as scientific research and carefully documented evidence, the Breggins expose the potentially damaging effects of Prozac. They also describe the resounding success that has been achieved with more humane alternatives for the treatment of depression. Talking Back to Prozac provides essential information for anyone who takes Prozac or is considering taking it, and for those who prescribe it. |
| antidepressants study casts doubt: Handbook of Cognitive Behavioral Approaches in Primary Care Robert A. DiTomasso, 2010 Print+CourseSmart |
| antidepressants study casts doubt: Against Depression Peter D. Kramer, 2006-07-25 Deeply felt... [Kramer's] book is a polemic against a society that accepts depression as a fact of life. —O, The Oprah Magazine A profound look at depression by the author of The New York Times Bestseller, Listening to Prozac In his landmark bestseller Listening to Prozac, Peter Kramer revolutionized the way we think about antidepressants and the culture in which they are so widely used. Now Kramer offers a frank and unflinching look at the condition those medications treat: depression. Definitively refuting our notions of heroic melancholy, he walks readers through groundbreaking new research—studies that confirm depression's status as a devastating disease and suggest pathways toward resilience. Thought-provoking and enlightening, Against Depression provides a bold revision of our understanding of mood disorder and promises hope to the millions who suffer from it. |
| antidepressants study casts doubt: The Book of Woe Gary Greenberg, 2013-05-02 “Gary Greenberg has become the Dante of our psychiatric age, and the DSM-5 is his Inferno.” —Errol Morris Since its debut in 1952, the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders has set down the “official” view on what constitutes mental illness. Homosexuality, for instance, was a mental illness until 1973. Each revision has created controversy, but the DSM-5 has taken fire for encouraging doctors to diagnose more illnesses—and to prescribe sometimes unnecessary or harmful medications. Respected author and practicing psychotherapist Gary Greenberg embedded himself in the war that broke out over the fifth edition, and returned with an unsettling tale. Exposing the deeply flawed process behind the DSM-5’s compilation, The Book of Woe reveals how the manual turns suffering into a commodity—and made the APA its own biggest beneficiary. |
| antidepressants study casts doubt: Speaking of Sadness David Allen Karp, 2017 Speaking of Sadness, based on fifty in-depth interviews, provides first-hand accounts of the depression experience while discovering clear regularities in the ways that personal identities are shaped over the course of an illness career. The new edition of the book is highlighted by a thoroughly new and extensive introduction-- |
| antidepressants study casts doubt: Common Mental Health Disorders National Collaborating Centre for Mental Health (Great Britain), 2011 Bringing together treatment and referral advice from existing guidelines, this text aims to improve access to services and recognition of common mental health disorders in adults and provide advice on the principles that need to be adopted to develop appropriate referral and local care pathways. |
| antidepressants study casts doubt: Depression, An Issue of Psychiatric Clinics David Mintz, 2012-03-28 This issue discusses the diagnosis and treatment of major depressive disorder (MDD) and other depressive disorders, with an emphasis on the psychosocial aspects of depression: how it affects societies, how it is affected by culture, and what the true meaning of recovery is for those suffering from MDD. The issue is divided into three section: Etiology, Diagnosis and Treatment. Authors address the evidence where biology and subjectivity meet. They discuss what is adaptive and what is pathologic and discuss population-based solutions that take into account the specificity of the individual. Authors also take into account combination treatments of psychotherapy and pharmacotherapy and weigh the treatment choices against specific patient subtypes. |
| antidepressants study casts doubt: Pharmacology and Physiology for Anesthesia E-Book Hugh C. Hemmings, Talmage D. Egan, 2018-10-19 Pharmacology and physiology are the foundation of every anesthesia provider's training and clinical competency. Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application, 2nd Edition, delivers the information you need in pharmacology, physiology, and molecular-cellular biology, keeping you current with contemporary training and practice. This thoroughly updated edition is your one-stop, comprehensive overview of physiology, and rational anesthetic drug selection and administration, perfect for study, review, and successful practice. - Contains new chapters on Special Populations (anesthetic pharmacology in obesity, geriatrics, and pediatrics), Oral and Non-IV Opioids, Thermoregulation, Physiology and Pharmacology of Obstetric Anesthesia, Chemotherapeutic and Immunosuppresive Drugs, and Surgical Infection and Antimicrobial Drugs. - Incorporates entirely new sections on Physics, Anatomy, and Imaging. - Includes new information on consciousness and cognition, pharmacodynamics, the immune system, and anti-inflammatory drugs. - Features user-friendly tables, figures, and algorithms (including 100 new illustrations), all presented in full color and designed to help explain complex concepts. - Helps you understand the molecular mechanism of drug actions and identify key drug interactions that may complicate anesthesia with dedicated sections on these areas. |
| antidepressants study casts doubt: When Baby Brings the Blues Ariel Dalfen, 2010-03-08 A leading expert on postpartum depression offers new mothers an insightful, medically sound guide to recovery A full 20 percent of new moms will be affected by PPD--but the good news is that PPD is very responsive to treatment. This guide, written by psychiatrist and internationally acclaimed PPD specialist Ariel Dalfen, leads women out of the maze of depression, offering medical and psychotherapeutic options, practical lifestyle changes, and an impressive array of resources for further support. Complete with a PPD diagnosis questionnaire, a treatment plan checklist, and a table of medications and side effects, this upbeat guide also includes daily affirmations used by Dr. Dalfen's own patients when recovering from PPD. Dr. Ariel Dalfen (Toronto, ON) is a psychiatrist at Mount Sinai Hospital in Toronto and an acclaimed lecturer and medical researcher in the area of post-partum depression. |
| antidepressants study casts doubt: Behavioral Emergencies, An Issue of Psychiatric Clinics of North America Nidal Moukaddam, Veronica Theresa Tucci, 2017-08-19 This issue of Psychiatric Clinics of North America, edited by Drs. Nidal Moukaddam, Veronica Tucci, will cover a wide arrange of topics in Behavioral Emergencies. Topics discussed in the issue include, but are not limited to: Medical Clearance of the Emergency Psychiatric Patient; Altered Mental State, Legal and Ethical Challenges in Emergency Psychiatry; Countertransference in the Clinical Setting; The Use of Psychotherapeutic Measures; Drugs of Abuse; Toxicological Emergencies in Patients With Mental Illness; Management of Depression and Suicidality in the Emergency Department; Special Considerations in the Pediatric Psychiatric Populations; Dementia and Special Considerations in the Geriatric Psychiatric Patient; The Changing Health Policy Environment and Behavioral Health Services Delivery; International Emergency Psychiatry Challenges; and Violence in the Emergency Department, among others. |
| antidepressants study casts doubt: Critical Thinking in Clinical Assessment and Diagnosis Barbara Probst, 2015-04-30 This much-needed volume brings to the clinician or student some of the best critical-minded analysis by some of the most insightful thinkers about psychiatric diagnosis today. The thought-provoking questions these essays raise, and the multifaceted and provocative answers they provide, cultivate sensitivity to the nuances of diagnostic assessment that often makes the difference between clinical success and failure. - Jerome C. Wakefield, PhD, DSW, New York University Silver School of Social Work, New York This transformative resource challenges social workers and mental health professionals to rethink their approaches to assessment and diagnosis from the ground up. Among the book’s unique features are its use of diverse lenses to examine a common case and its illustration of how multiple perspectives can be integrated for a richly textured portrait of the individual in context. Equally crucial is the book’s commitment to professional development, from exercises to improve case conceptualization to strategies for teaching and learning. Topics include: The DSM-5 definition of mental disorder: critique and alternatives. Making assessment decisions: macro, mezzo, and micro perspectives. Neuroscience, resilience, and the embodiment of “mental” disorder. Narrative, psychodynamic, and cultural conceptualizations of disorder. Person-centered and contextualized diagnosis in mental health. Meeting the challenge of teaching integrated assessment. Critical Thinking in Clinical Assessment and Diagnosis has much to offer professionals, researchers, and educators in the fields of social work and mental health. . |
| antidepressants study casts doubt: Psychiatry Under the Influence R. Whitaker, L. Cosgrove, 2015-04-23 Psychiatry Under the Influence investigates the actions and practices of the American Psychiatric Association and academic psychiatry in the United States, and presents it as a case study of institutional corruption. |
| antidepressants study casts doubt: Functional Medicine for Antidepressant Withdrawal James Greenblatt, Jennifer C. Dimino, 2022-06-27 Since the days of the “Psychopharm Revolution,” antidepressant medications such as SSRIs and SNRIs have been a foundation of modern psychiatric practice. Today, 40 million Americans take antidepressants, and global antidepressant prescribing is on the rise. Simultaneously, however, a gap has emerged between pharmacologic innovation and methodology. Amidst patient reports of antidepressant side effects, evidence is mounting that antidepressant discontinuation often leads to withdrawal - which can be severe. And although today’s clinicians are trained how to prescribe antidepressants, they are not trained how to safely stop them. There is currently zero field-wide consensus regarding antidepressant discontinuation best practices. In addition to a stunning ethical failure, this represents a serious void in the psychiatric model... a riddle that too many patients and clinicians are being forced to solve alone. Functional Medicine for Antidepressant Withdrawal presents a comprehensive, evidence-based paradigm for antidepressant discontinuation that prioritizes the repletion of underlying nutritional deficiencies. Bridging concept and application, it provides health professionals with clinically proven tools for mitigating antidepressant withdrawal and guiding patients successfully through taper. It also reveals a path to the standard of care that we all deserve, one illuminated by science and upheld by the mandates of ethical, conscientious, personalized medicine. |
| antidepressants study casts doubt: Drug Selectivity Norbert Handler, 2018-02-27 The book Drug Selectivity - An Evolving Concept in Medicinal Chemistry provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist. |
| antidepressants study casts doubt: Foundations of Qualitative Research Jerry W. Willis, 2007-01-26 Willis catches the student up on relevant aspects of philosophy, empiricism, history, and prevailing political influences. This building of chronology is so valuable for students in understanding the origins of specific schools of thought in relations to a paradigm. —Heather T. Zeng, NACADA Foundations of Qualitative Research introduces key theoretical and epistemological concepts replete with historical and current real-world examples. Author Jerry W. Willis provides an invaluable resource to guide the critical and qualitative inquiry process written in an accessible and non-intimidating style that brings these otherwise difficult concepts to life. Key Features: Covers the conceptual foundations of interpretive, critical, and post-positivist paradigms: A thorough background of theory and social inquiry is given by looking at the development of each paradigm throughout history. Provides real-world examples: Cases illustrate different approaches to the same research problem so that students can better understand the contrasting features of these paradigms. Introduces seven qualitative research frameworks: In-depth coverage is provided on Altheide and Johnson′s Analytic Realism; Denzin and Lincoln′s Interpretive Perspective; Eisner′s Connoisseurship Model of Inquiry; Semiotics; the Phenomenological Psychological Model; Poststructuralism and Postmodernism; and Symbolic Interactionism. Offers general guidelines for qualitative research: Conceptually covers the best practices, approaches to data analysis, and interpretation of qualitative research. Examines emergent methods in qualitative research: New research areas such as PAR, emancipatory research, and participatory design research are included, as well as exemplary journal articles to further illustrate how theory links to research practice. Intended Audience: This text is designed for advanced undergraduate and graduate students taking their first or second qualitative research methods course in the fields of Education, Psychology, and the Health and Social Sciences. It is also an excellent theory companion supplement to the more applied qualitative methods text. |
List of Antidepressants + Uses, Types, Side Effects - Drugs.com
Apr 17, 2023 · Antidepressants help to relieve symptoms of depression such as low mood, irritability, feelings of worthlessness, restlessness, anxiety, and difficulty sleeping. …
Antidepressants: Selecting one that's right for you - Mayo Clinic
Antidepressants are a popular treatment choice for depression. Although antidepressants may not cure depression, they can reduce symptoms. The first antidepressant you try may work fine. …
28 Antidepressants Types, Side Effects, List & Alcohol Interactions
Oct 16, 2018 · Antidepressants (depression medications) most commonly are used to treat depression. Types of antidepressants are SSRIs, SNRIs, TCAs, and MAOIs. Common side …
Antidepressants: Types, side effects, uses, and effectiveness
Jan 26, 2024 · Antidepressants can help relieve symptoms of conditions such as depression and anxiety disorders. They work by increasing neurotransmitters in the brain. Examples of …
Antidepressants - StatPearls - NCBI Bookshelf
May 26, 2023 · Antidepressants are the drug of choice for depression, but they also have FDA approval as treatments for other medical disorders.
Types of Antidepressants: SSRIs, SNRIs, and More - WebMD
Jun 7, 2024 · WebMD explains the different types of antidepressants and how to talk to your doctor about finding one that can help your depression symptoms.
Depression Medications (Antidepressants) - WebMD
Jun 16, 2024 · Antidepressants work by reducing depression symptoms such as exhaustion, low mood, loss of interest, restlessness, anxiety, and problems sleeping. They also help prevent …
Overview - Antidepressants - NHS
Antidepressants are a type of medicine used to treat clinical depression. They can also be used to treat a number of other conditions, including: obsessive compulsive disorder (OCD)
What Are the Top 10 Antidepressant Drugs? - eMedicineHealth
Antidepressant drugs are used to treat depression, depression with anxiety, and depression associated with bipolar disorder or cyclothymic disorder. They may also be prescribed for pain …
Antidepressants - MedlinePlus
Mar 17, 2025 · Many people take antidepressants. Learn about antidepressant side effect, the different types of antidepressants, and more.
List of Antidepressants + Uses, Types, Side Effects - Drugs.com
Apr 17, 2023 · Antidepressants help to relieve symptoms of depression such as low mood, irritability, feelings of worthlessness, restlessness, anxiety, and difficulty sleeping. …
Antidepressants: Selecting one that's right for you - Mayo Clinic
Antidepressants are a popular treatment choice for depression. Although antidepressants may not cure depression, they can reduce symptoms. The first antidepressant you try may work fine. …
28 Antidepressants Types, Side Effects, List & Alcohol Interactions
Oct 16, 2018 · Antidepressants (depression medications) most commonly are used to treat depression. Types of antidepressants are SSRIs, SNRIs, TCAs, and MAOIs. Common side …
Antidepressants: Types, side effects, uses, and effectiveness
Jan 26, 2024 · Antidepressants can help relieve symptoms of conditions such as depression and anxiety disorders. They work by increasing neurotransmitters in the brain. Examples of …
Antidepressants - StatPearls - NCBI Bookshelf
May 26, 2023 · Antidepressants are the drug of choice for depression, but they also have FDA approval as treatments for other medical disorders.
Types of Antidepressants: SSRIs, SNRIs, and More - WebMD
Jun 7, 2024 · WebMD explains the different types of antidepressants and how to talk to your doctor about finding one that can help your depression symptoms.
Depression Medications (Antidepressants) - WebMD
Jun 16, 2024 · Antidepressants work by reducing depression symptoms such as exhaustion, low mood, loss of interest, restlessness, anxiety, and problems sleeping. They also help prevent …
Overview - Antidepressants - NHS
Antidepressants are a type of medicine used to treat clinical depression. They can also be used to treat a number of other conditions, including: obsessive compulsive disorder (OCD)
What Are the Top 10 Antidepressant Drugs? - eMedicineHealth
Antidepressant drugs are used to treat depression, depression with anxiety, and depression associated with bipolar disorder or cyclothymic disorder. They may also be prescribed for pain …
Antidepressants - MedlinePlus
Mar 17, 2025 · Many people take antidepressants. Learn about antidepressant side effect, the different types of antidepressants, and more.
