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| arteriosclerosis thrombosis and vascular biology: Arteriosclerosis, Thrombosis, and Vascular Biology Donald Heistad, 2003 The American Heart Association (AHA) presents information about the monthly journal Arteriosclerosis, Thrombosis, and Vascular Biology. The publication is aimed at academic cardiologists, vascular biologists, physiologists, pharmacologists, and hematologists. The AHA offers online access to subscribers. |
| arteriosclerosis thrombosis and vascular biology: Oxidative Stress and Vascular Disease John F. Keaney Jr., 1999-12-31 One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, there is still uncertainty as to the exact mechanisms by which elevated plasma cholesterol and LDL levels initiate and favor the progression of lesions. There is general consensus that one of the earliest responses to hypercholesterolemia is the adhesion of monocytes to aortic endothelial cells followed by their penetration into the subendothelial space, where they differentiate into macrophages. These cells, and also medial smooth muscle cells that have migrated into the subendothelial space, then become loaded with mUltiple, large droplets of cholesterol esters . . . the hallmark of the earliest visible atherosclerotic lesion, the so-called fatty streak. This lesion is the precursor of the more advanced lesions, both in animal models and in humans. Thus the centrality of hypercholesterolemia cannot be overstated. Still, the atherogenic process is complex and evolves over a long period of time. |
| arteriosclerosis thrombosis and vascular biology: Coronary Vasomotion Abnormalities Hiroaki Shimokawa, 2020-12-08 This book reviews the latest findings on epicardial coronary spasm and coronary microvascular dysfunction (CMD), important diseases for understanding coronary artery vasomotion abnormalities. The book chiefly consists of two major parts, each of which explores the epidemiology, pathophysiology, diagnosis and treatment of the diseases. The chapters present a range of experimental and clinical studies, including the editor’s life’s work on coronary spasm; how Rho-kinase activation plays an important role in connection with the disease; how chronic adventitial inflammation is a central pathophysiology of the spasm; the importance of Rho-kinase activation in the pathogenesis of CMD; how epicardial spasm and CMD frequently co-exist; and much more. Coronary Vasomotion Abnormalities will help practicing cardiologists, cardiac surgeons, vascular biologists and radiologists understand the latest issues concerning the clinical, interventional, and surgical management of these conditions, and offer these readers valuable insights into the effective treatment of microvascular angina. |
| arteriosclerosis thrombosis and vascular biology: Mechanisms of Vascular Disease Robert Fitridge, M. M. Thompson, 2011 New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes. |
| arteriosclerosis thrombosis and vascular biology: Atherosclerosis and Autoimmunity Yehuda Shoenfeld, D. Harats, G. Wick, 2001-02-27 Presenting further studies in the prevention and treatment of coronary artery disease, this book brings together the knowledge accrued in the past decade concerning the role of immunity in the initiation and perpetuation of atherosclerosis. A strong group of international contributors summarize the diverse aspects of the interrelationship between the immune system and atherosclerosis. |
| arteriosclerosis thrombosis and vascular biology: Atherosclerosis Luigi Gianturco, 2018-08-01 Atherosclerosis is a subject of enormous contention for cardiologists and in general for all medical doctors. With this publication we have given you a concise state-of-the-art look at the world of atheroma. Many other elements could be included and so it is only a brief analysis of today (the preventive medicine era) and tomorrow (transforming the cure medicine era into the care medicine era) but also remembering yesterday (the ex-cathedra medicine era). Let's hope our arteries are free from atherosclerotic events: have a good read! |
| arteriosclerosis thrombosis and vascular biology: Fundamentals of Vascular Biology Margarethe Geiger, 2019-05-08 This well-structured textbook offers essential knowledge on the vascular system. The reader will learn the properties, basic cellular mechanisms and development of the different parts of the vascular system (including the heart), gain knowledge on vascular and related diseases, and will be made familiar with common and most current methods and techniques applied to analyze the vascular system in patients, in animal models, and ex vivo. This book is based on a PhD Course for students from various bioscientific backgrounds given at the Medical University of Vienna, and it will be a valuable resource for Master ́s Students in vascular biology and biomedicine in general and a helpful tool for young researchers world-wide wishing to gain or refresh their knowledge in this field. |
| arteriosclerosis thrombosis and vascular biology: The ESC Textbook of Vascular Biology Rob Krams, Magnus Bäck, 2017 The ESC Textbook of Vascular Biology is a rich and clearly laid-out guide by leading European scientists providing comprehensive information on vascular physiology, disease, and research. |
| arteriosclerosis thrombosis and vascular biology: The Biology of Cholesterol and Related Steroids N. B. Myant, 2014-04-24 The Biology of Cholesterol and Related Steroids focuses on the study of sterols in relation to living organisms. The publication first takes a look at the analysis of sterols and related steroids and the distribution of sterols and related steroids in nature, as well as the processes of extraction and separation and presence of sterols in plants, fungi, vertebrates, and invertebrates. The text then ponders on biosynthesis of sterols and metabolism of cholesterol. Topics include formation of fatty acid esters of cholesterol, steroid hormones, biosynthetic pathway to sterols, reaction mechanisms, and comparative aspects of sterol synthesis. The manuscript examines the developmental aspects of cholesterol metabolism and sterols in biological membranes. The book also reviews cholesterol synthesis in animal tissues, sterol metabolism in isolated cells, and epidemiology of the plasma cholesterol. Discussions focus on selection of statistical populations, genetic influences, regulation of sterol synthesis, general aspects of sterol metabolism, and removal of cell cholesterol in vivo. The publication is a dependable source of data for biochemists and readers interested in the biology of cholesterol and steroids. |
| arteriosclerosis thrombosis and vascular biology: How Tobacco Smoke Causes Disease United States. Public Health Service. Office of the Surgeon General, 2010 This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products. |
| arteriosclerosis thrombosis and vascular biology: The Vascular Endothelium II Salvador Moncada, Annie Higgs, 2006-10-14 This wide ranging work provides a complete representation of the present state of knowledge of the vascular endothelium. The volume comprises 20 chapters by experts who have made significant contributions to research in the vascular endothelium. The text discusses the structure, development and function of the normal vascular endothelium, considers conditions that lead to the disruption of vascular physiology and provides a comprehensive description of pathologies and their treatment. |
| arteriosclerosis thrombosis and vascular biology: Endothelial Dysfunction Helena Lenasi, 2018-10-24 The endothelium enables communication between blood and tissues and is actively involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an early step in the development of cardiovascular diseases: respectively, endothelium represents a potential therapeutic niche with multiple targets. The purpose of the book is to point out some recent findings of endothelial physiology and pathophysiology emphasizing various aspects of endothelial dysfunction connected to the body's internal and external environment. While basic features of the endothelium are presented in an introductory chapter, the authors of the following 17 chapters have provided extensive insight into some selected topics of endothelial (dys)function. The book would hopefully be useful for anyone interested in recapitulating endothelial (patho)physiology and expanding knowledge of molecular mechanisms involved in endothelial dysfunction, relevant also for further clinical investigations. |
| arteriosclerosis thrombosis and vascular biology: Hemodynamics and Mechanobiology of Endothelium Tzung K. Hsiai, Brett Blackman, Hanjoong Jo, 2010 The book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress. The investigation of vascular biology and cardiovascular medicine is made possible by the use of tissue engineering, nanotechnology and stem cell research. This is the first textbook to target a wide readership from academia to industry and government agencies in the field of cardiovascular diseases. |
| arteriosclerosis thrombosis and vascular biology: Mechanisms of Vascular Disease Robert Fitridge, 2020-07-30 This extensively revised third edition provides a practically applicable guide to the pathophysiology, assessment and management of vascular disorders encountered in vascular surgical practice. It features detailed information on the latest developments in the pathophysiology of conditions including atherosclerosis, multi-organ failure, limb compartment syndromes and Raynaud’s phenomenon in a clear easy to digest format. Disorders such as reperfusion injuries, vasculitides, and aortic dissection are covered. Furthermore, key topics in vascular and endovascular practice such as radiation biology and radiation safety are also detailed. Each chapter contains a set of learning objectives and key references, enabling the reader to quickly identify key points. Mechanisms of Vascular Disease: A Textbook for Vascular Specialists comprehensively covers a variety of common and unusual pathophysiologies encountered in vascular surgery, and is an ideal resource for both the trainee, and practicing clinical vascular surgeon seeking an up-to-date resource on the topic. |
| arteriosclerosis thrombosis and vascular biology: Atherosclerosis, Arteriosclerosis and Arteriolosclerosis Luigi Gianturco, 2020-05-20 With high morbidity and mortality rates, atherosclerosis (ATS) is a major concern worldwide. This book provides comprehensive information on ATS, including chapters on cardiovascular disease and obstructive sleep apnea, rheumatology and cardiovascular risk, and the differences of ATS among men and women. Let’s hope for the best and thank you to all my team for collaborating in this book production. In particular, thanks • to Bruno (my expert colleague) and Aurel (my secretary) for analyzing and reading with me all the texts • to Vincenzo, Stefano and Andrea for English evaluation • and finally to Rebecca (my future wife) for sustaining me in all professional activities giving me power in daily life! |
| arteriosclerosis thrombosis and vascular biology: Interventional Cardiology George D. Dangas, Carlo Di Mario, Nicholas N. Kipshidze, Peter Barlis, Tayo Addo, 2016-11-28 Expert guidance from internationally recognized authorities, who provide clear and current updates on all aspects of interventional cardiology. This new edition; Contains a radically expanded chapter contents list presented in four clear sections; coronary interventions, interventional pharmacology, structural heart interventions, and endovascular therapy Includes 46 new chapters, including the latest advances in bioresorbable coronary stents, advanced transcatheter aortic valve replacement, MitraClip, new transcatheter mitral valve interventions, and more Chapters are templated for rapid referral, beginning with pathophysiological background and relevant pathology, moving to mechanisms of treatment, device description, procedural techniques, follow-up care, and ending with risks, contraindications and complications Multiple choice questions at the end of each chapter for self-assessment, a total of more than 400 MCQs in the book Features 19 procedural videos, hosted on a companion website |
| arteriosclerosis thrombosis and vascular biology: New Insight into Cerebrovascular Diseases Patricia Bozzetto Ambrosi, Rufai Ahmad, Auwal Abdullahi, Amit Agrawal, 2020-05-13 “Brain circulation is a true road map that consists of large extended navigation territories and a number of unimagined and undiscovered routes.” Dr. Patricia Bozzetto Ambrosi This book combines an update on the review of cerebrovascular diseases in the form of textbook chapters, which has been carefully reviewed by Dr. Patricia Bozzetto Ambrosi, Drs. Rufai Ahmad and Auwal Abdullahi and Dr. Amit Agrawal, high-performance academic editors with extensive experience in neurodisciplines, including neurology, neurosurgery, neuroscience, and neuroradiology, covering the best standards of neurological practice involving basic and clinical aspects of cerebrovascular diseases. Each topic was carefully revised and prepared using smooth, structured vocabulary, plus superb graphics and scientific illustrations. In emphasizing the most common aspects of cerebrovascular diseases: stroke burden, pathophysiology, hemodynamics, diagnosis, management, repair, and healing, the book is comprehensive but concise and should become the standard reference guide for this neurological approach. |
| arteriosclerosis thrombosis and vascular biology: The Vascular Smooth Muscle Cell , 1995-10-24 In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (SMC) in tissue undergoing both differentiation and repair. These developments have led to increased research on SMC. The latest volume in the Biology of the Extracellular Matrix Series takes a current and all-encompassing look at this growing area of research. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development. It also examines the proliferation and replication of SMC and its role in pharmacology and vascular disease. A must for cell, developmental, and molecular biologists, this book also will appeal to cardiologists, pathologists, and biomedical researchers interested in smooth muscle cells. - Presents a molecular, genetic, and developmental perspective of the vas smooth muscle cell - Overview sections highlight key points of chapters, including the clinical relevance of the research and expectations for future study - Appeals to both the basic biologist and to the biomedical researcher of vascular disease |
| arteriosclerosis thrombosis and vascular biology: Mechanobiology Simon C. F. Rawlinson, 2017-01-31 An emerging field at the interface of biology and engineering, mechanobiology explores the mechanisms by which cells sense and respond to mechanical signals—and holds great promise in one day unravelling the mysteries of cellular and extracellular matrix mechanics to cure a broad range of diseases. Mechanobiology: Exploitation for Medical Benefit presents a comprehensive overview of principles of mechanobiology, highlighting the extent to which biological tissues are exposed to the mechanical environment, demonstrating the importance of the mechanical environment in living systems, and critically reviewing the latest experimental procedures in this emerging field. Featuring contributions from several top experts in the field, chapters begin with an introduction to fundamental mechanobiological principles; and then proceed to explore the relationship of this extensive force in nature to tissues of musculoskeletal systems, heart and lung vasculature, the kidney glomerulus, and cutaneous tissues. Examples of some current experimental models are presented conveying relevant aspects of mechanobiology, highlighting emerging trends and promising avenues of research in the development of innovative therapies. Timely and important, Mechanobiology: Exploitation for Medical Benefit offers illuminating insights into an emerging field that has the potential to revolutionise our comprehension of appropriate cell biology and the future of biomedical research. |
| arteriosclerosis thrombosis and vascular biology: Platelets Alan D. Michelson, 2011-08-29 Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. - First edition won Best Book in Medical Science Award from the Association of American Publishers - Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias - A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references |
| arteriosclerosis thrombosis and vascular biology: Physiologic and Pathologic Angiogenesis Dan Simionescu, Agneta Simionescu, 2017-04-05 The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all. |
| arteriosclerosis thrombosis and vascular biology: Thrombosis Sol Sherry, National Research Council (U S ) Task, International Committee on Haemostasis, 2023-07-18 Thrombosis is a groundbreaking study of blood clotting disorders, which can cause serious health problems such as heart attacks and strokes. Drawing on the latest research in the field, this book offers a comprehensive overview of the causes, symptoms, and treatment options for thrombosis. Written by leading experts in hematology and cardiology, this book is an invaluable resource for healthcare professionals and patients alike. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. |
| arteriosclerosis thrombosis and vascular biology: Vascular Access Surgery Alexander Berezin, 2019-04-24 Decision-making regarding the route of access to minimize procedural complications, especially in patients with unusual or complicated vascular anatomy, is extremely important for successful vascular access surgery. Several techniques for vascular access are widely disputed in the context of achieving optimal clinical outcomes. This book discusses various clinical aspects of vascular access to enrich our knowledge and understanding of the contemporary methodology and management of vascular access for a broad range of purposes. In four sections, this book examines the following topics: 1. Vascular Access: Methodology and Contemporary Management; 2. Vascular Access and Reparative Surgery; 3. Vascular Access Failure; and 4. Risk Stratification in Vascular Access. |
| arteriosclerosis thrombosis and vascular biology: Atherosclerosis Hong Wang, Cam Patterson, 2015-05-11 Comprehensive and in-depth in its coverage, Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy reviews the recent progress in atherosclerosis research and offers cutting edge perspectives from experts in the field. Written by an international team of authors including leading physician-scientists, research experts and physicians, chapters are divided into four major sections, covering risk factors, cellular and molecular mechanisms, biochemical mechanisms and novel and future therapeutics. Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy analyses recent progress from both conceptual and technological perspectives, suggesting new directions for atherosclerosis research and treatment for a growing population of researchers and clinicians in cardiovascular and related fields. |
| arteriosclerosis thrombosis and vascular biology: Statin-Associated Muscle Symptoms Paul D. Thompson, Beth A. Taylor, 2020-01-25 This book provides an overview of statin-associated muscle symptoms (SAMS) from clinical presentation to treatment and possible metabolic causes. It examines the risk factors, presentations, diagnosis and differential diagnosis, clinical management, and financial costs of SAMS. The book also highlights patients’ perspectives on SAMS such as the psychosocial, emotional, and societal factors influencing their perceptions and experiences. Finally, the book presents the results of observational and clinical trials on the prevalence of SAMS, clinical trials for treatments, and potential future research approaches for improving the understanding and treatment of SAMS. A key addition to the Contemporary Cardiology series, Statin-Associated Muscle Symptoms is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in cardiology, endocrinology, pharmacotherapy, primary care, and health promotion and disease prevention. |
| arteriosclerosis thrombosis and vascular biology: Hypoxia and Anoxia Kusal Das, Mallanagouda Shivanagouda Biradar, 2018-12-12 The molecular deprivation of oxygen is manifested by hypoxia, a deficiency of oxygen and anoxia, or the absence of oxygen supply to the tissues. This book entitled Hypoxia and Anoxia will cover a broad range of understanding on hypoxia and anoxia from molecular mechanisms to pathophysiology. Hypoxia and anoxia stimulate multiple systems through specific cell signal transduction pathways and regulate several transcriptional factors like HIF-1, REST to encode genes for VEGF, Epo, etc. This book will also highlight different types of hypoxia and anoxia along with their impact on apoptosis, cardiovascular pathophysiology, and glucose regulatory mechanisms. This book will be a ready reckoner to give a deep understanding of the oxygen-sensing environment in vivo for researchers, academicians, and clinicians throughout the world. |
| arteriosclerosis thrombosis and vascular biology: Calcific Aortic Valve Disease Elena Aikawa, 2013-06-12 Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future. |
| arteriosclerosis thrombosis and vascular biology: Swine in Biomedical Research Mike E. Tumbleson, 1986 |
| arteriosclerosis thrombosis and vascular biology: The Recombinant DNA Controversy Donald S. Fredrickson, 2001 Relying on vast archives of hearings records, correspondence, and extensive personal records and diaries, Dr. Fredrickson recalls the numerous personalities from microbiology, molecular biology, and other scientific disciplines, as well as the leaders among Congress, the administration, and government agencies, environmentalists, and many others, who had a role during this challenging period.--BOOK JACKET. |
| arteriosclerosis thrombosis and vascular biology: The MIF Handbook Richard Bucala, 2012 The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science. |
| arteriosclerosis thrombosis and vascular biology: Biology of the Arterial Wall Bernard I. Levy, Alain Tedgui, 2007-11-23 Biology of the Arterial Wall is intended as a general reference text concerned with the biology of the vascular cells and the blood vessel wall under physiological and pathological conditions. One of the major functions of the arteries is to maintain a continuous blood flow to the organs whatever the pressure conditions, thanks to the vasomotor tone of the smooth muscle cells. Great advances have been made over the last decade in the understanding of the endothelial cells as integrators and transducers of signals originating from the blood stream. The pluripotent control functions of the endothelial cells in the vessel wall are now well recognized. A review of endothelial functions and dysfunctions is presented. Cell biology and molecular genetic studies have now identified an array of molecules elaborated by endothelial cells and vascular smooth muscle cells and by the blood-borne elements which interact with artery cells, defending the artery against injury and modulating evolving abnormal processes. Molecules which induce or inhibit endothelial and/or smooth muscle cells are currently under great scrutiny. Angiogenesis, which plays a major role in tumor growth, but may also be beneficial as a healing process in muscle ischemia, is discussed. Apoptosis, or programmed cell death, has only recently been recognized as an essential process in blood vessel modeling and remodeling. An overview of apoptosis in the vascular system is presented. It is increasingly evident that the adjustments of the blood vessel wall are made in the presence of deforming disease processes such as hypertension and atherosclerosis. The second part of the book is concerned with the blood vessel wall in disease conditions. Several chapters review the role of the vessel and vascular cells in inflammation, and vascular remodeling during arterial hypertension and aging. One chapter is devoted to atherogenesis, atheroma and plaque instability, followed by the pathophysiology of post-angioplasty restenosis, which is a crucial issue in modern interventional cardiology. |
| arteriosclerosis thrombosis and vascular biology: Cardiovascular Health and Disease in Women Pamela S. Douglas, 2002 This practical resource takes a close look at an emerging issue in woman's health*the gender difference in cardiovascular disease. Health care providers involved in the care of female patients can rely on this extraordinary reference for the latest coverage of cardiovascular health and disease. The new 2nd Edition features an expanded scope that offers more information on patient care approaches, risk factors, hormones and CAD, and more. New chapters cover hot topics such as estrogen, diet and nutrition, first- and second-degree prevention strategies, managing CAD, and acute coronary syndromes. A much broader scope presents more information on patient care, risk factors, hormones and CAD, and clinical manifestations of CAD. New authors bring an up-to-date perspective to material that focuses on their areas of expertise. New chapters provide the latest information on hot topics, including: Nutrition, Antioxidants and Inflammation, Primary Prevention in Women, Lessons from Human Trials, Management of Chronic Stable Angina, Acute Coronary Syndromes, Angiography and Angioplasty, Coronary Artery Surgery, Implementation Strategies for Secondary Prevention, Syndrome X and Coronary Vascular Resistance, and Normal Cardiovascular Physiology Updates and new information have been incorporated throughout, and substantial revisions have been made to chapters on: Diabetes Mellitus and Obesity, Smoking, Clotting and Thrombosis, Physical Activity, Lessons from Animal Models, Prescribing HRT, Diagnostic Testing Valvular Heart Disease, CHF and Myocardial Dysfunction, Stroke and PVD, Preexisting Heart Disease, and Diagnostic and Therapeutic Strategies Expanded discussions of estrogen address both the underlying science and clinical applications for practice Strategies for first- and second-degree prevention of disease offer a proactive approach to treatment and patient care |
| arteriosclerosis thrombosis and vascular biology: Vascular Biology Marcelo González, 2020-11-11 The two main causes of death in the world are directly related to cardiovascular system disorders, ischemic heart disease, and stroke. These pathological conditions are caused by complex molecular mechanisms related to endothelial dysfunction and, finally, structural and functional alterations of blood vessels. Clinical evidence demonstrates the relevance of knowledge about vascular biology, from molecular mechanisms to clinical applications, especially for students of medical sciences or basic sciences. This book is an international effort of collaboration, with the purpose to create an academic tool for students or people interested in learning about vascular biology. I invite the readers to check the chapters and explore the topics developed by experts in the field. |
| arteriosclerosis thrombosis and vascular biology: Glycans in Diseases and Therapeutics Mauro S.G. Pavão, 2011-04-19 Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions. This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents. |
| arteriosclerosis thrombosis and vascular biology: Extracellular Vesicles in Health and Disease Paul Harrison, Chris Gardiner, Ian L. Sargent, 2014-05-02 Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role in pathogenesis as well as their possible use as biomarkers. This book stems from the first international meeting on Microvesicles and Nanovesicles in Health and Disease held at Magdalen College, Oxford, in 2010. The purpose of the meeting was to bring together, for the first time, a range of experts from around the world to discuss the latest advances in this field. Key to the study of these vesicles is the availability of methodologies for their measurement in biological fluids. A major section of the meeting focused on a range of exciting new technologies which have been developed for this purpose. The presentations at this meeting form the basis of this book, which will appeal to basic scientists, clinicians, and those developing technology for the measurement of extracellular vesicles. |
| arteriosclerosis thrombosis and vascular biology: Cardiovascular Medicine James T. Willerson, Jay N. Cohn, Hein J.J. Wellens, David R. Holmes, 2007-12-06 This book offers the most up-to-date, user-friendly guidance on the evaluation, diagnosis and medical and surgical treatment of heart and vascular disease. The book and DVD package is designed to provide comprehensive coverage of every aspect of cardiovascular medicine. The book has consistent chapter organization relevant to modern cardiovascular practice, clear design and engaging text. The reader will have all the guidance to diagnose and manage the full range of cardiovascular conditions in one textbook resource, while also benefiting from access to additional video material from the integral DVD-ROM. This includes over 100 individual heart sounds. |
| arteriosclerosis thrombosis and vascular biology: Atherothrombosis and Coronary Artery Disease Valentin Fuster, Eric J. Topol, Elizabeth G. Nabel, 2005 Written by the world’s foremost authorities, this volume provides comprehensive coverage of current approaches to the prevention, diagnosis, and management of atherothrombosis and its coronary and noncoronary complications. This edition has been thoroughly updated, sharply focused on clinical information, and trimmed to one manageable volume. Coverage begins with a review of risk factors and prevention, emphasizing lipid abnormalities, hypertension, smoking, diabetes, and obesity. Subsequent sections examine the pathogenesis of atherosclerosis, markers and imaging, acute coronary syndromes, chronic stable angina, and noncoronary atherothrombosis. Clinical presentations, medical management, and the latest interventional strategies are included. |
| arteriosclerosis thrombosis and vascular biology: Management of Dyslipidemia Wilbert S. Aronow, 2021-07-21 Dyslipidemia is a major risk factor for cardiovascular events, cardiovascular mortality, and all-cause mortality. The earlier in life dyslipidemia is treated, the better the prognosis. The current book is an excellent one on dyslipidemia written by experts on this topic. This book includes 12 chapters including 5 on lipids, 4 on hypercholesterolemia in children, and 3 on the treatment of dyslipidemia. This book should be read by all health care professionals taking care of patients, including pediatricians since atherosclerotic cardiovascular disease begins in childhood. |
| arteriosclerosis thrombosis and vascular biology: Hypertension, Physiopathology and Treatment Jacques Genest, 1983 |
| arteriosclerosis thrombosis and vascular biology: Stroke Genetics Hugh S. Markus, 2003 Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. An increasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently sporadic stroke. Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemic stroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence is reviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing a practical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites. |
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology. Leading basic, translational, clinical, and population research related to arteriosclerosis, thrombosis, and vascular biology. Editor-in …
Arteriosclerosis, Thrombosis, and Vascular Biology - Wikipedia
Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) is a peer-reviewed medical journal published on behalf of the American Heart Association by Lippincott Williams & Wilkins, an …
Arteriosclerosis, Thrombosis, Vascular Biology Community
The ATVB Council focuses on arteriosclerosis, thrombosis and vascular biology. The council advances research, addresses prevention, improves diagnosis and treatment, and works …
Arteriosclerosis, Thrombosis, and Vascular Biology - LWW
Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) is an essential resource for cardiologists committed to staying at the forefront of cardiovascular, peripheral vascular, and …
Vol 45, No 6 | Arteriosclerosis, Thrombosis, and Vascular Biology
May 21, 2025 · Epigenetic Modulation of Vascular Smooth Muscle Cell Phenotype Switching in Early-Onset Acute Myocardial Infarction
American Heart Association Journals
National Center. 7272 Greenville Ave.Dallas, TX 75231. Customer Service. 1-800-AHA-USA-1. 1-800-242-8721. Hours. Monday - Friday: 7 a.m. – 7 p.m. CT. Saturday: 9 a ...
Hemodynamic Environments for the Progression of Carotid ...
4 days ago · BACKGROUND: Hemodynamic stress plays an important role in the development of atherosclerosis. It is difficult to sufficiently predict the progression of atherosclerosis and …
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology. Leading basic, translational, clinical, and population research related to arteriosclerosis, thrombosis, and vascular biology. Editor-in …
Arteriosclerosis, Thrombosis, and Vascular Biology - Wikipedia
Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) is a peer-reviewed medical journal published on behalf of the American Heart Association by Lippincott Williams & Wilkins, an …
Arteriosclerosis, Thrombosis, Vascular Biology Community
The ATVB Council focuses on arteriosclerosis, thrombosis and vascular biology. The council advances research, addresses prevention, improves diagnosis and treatment, and works …
Arteriosclerosis, Thrombosis, and Vascular Biology - LWW
Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) is an essential resource for cardiologists committed to staying at the forefront of cardiovascular, peripheral vascular, and …
Vol 45, No 6 | Arteriosclerosis, Thrombosis, and Vascular Biology
May 21, 2025 · Epigenetic Modulation of Vascular Smooth Muscle Cell Phenotype Switching in Early-Onset Acute Myocardial Infarction
American Heart Association Journals
National Center. 7272 Greenville Ave.Dallas, TX 75231. Customer Service. 1-800-AHA-USA-1. 1-800-242-8721. Hours. Monday - Friday: 7 a.m. – 7 p.m. CT. Saturday: 9 a ...
Hemodynamic Environments for the Progression of Carotid ...
4 days ago · BACKGROUND: Hemodynamic stress plays an important role in the development of atherosclerosis. It is difficult to sufficiently predict the progression of atherosclerosis and …
