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| clinimacs prodigy user manual pdf: The EBMT Handbook Nicolaus Kröger, Mohamad Mohty, Carlo Dufour, 2020-10-08 This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors. |
| clinimacs prodigy user manual pdf: The EBMT/EHA CAR-T Cell Handbook Nicolaus Kröger, John Gribben, Christian Chabannon, Ibrahim Yakoub-Agha, Hermann Einsele, 2022-02-07 This first open access European CAR-T Handbook, co-promoted by the European Society for Blood and Marrow Transplantation (EBMT) and the European Hematology Association (EHA), covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers’ knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers’ knowledge and practice skills. |
| clinimacs prodigy user manual pdf: Cell and Gene Therapies Miguel-Angel Perales, Syed A. Abutalib, Catherine Bollard, 2018-11-27 In this book, experts in the field express their well-reasoned opinions on a range of complex, clinically relevant issues across the full spectrum of cell and gene therapies with the aim of providing trainee and practicing hematologists, including hematopoietic transplant physicians, with information that is relevant to clinical practice and ongoing research. Each chapter focuses on a particular topic, and the concise text is supported by numerous working tables, algorithms, and figures. Whenever appropriate, guidance is provided regarding the availability of potentially high-impact clinical trials. The rapid evolution of cell and gene therapies is giving rise to numerous controversies that need to be carefully addressed. In meeting this challenge, this book will appeal to all residents, fellows, and faculty members responsible for the care of hematopoietic cell transplant patients. It will also offer a robust, engaging tool to aid vital activities in the daily work of every hematology and oncology trainee. |
| clinimacs prodigy user manual pdf: Contemporary Bone Marrow Transplantation Mammen Chandy, Vivek S. Radhakrishnan, Reghu K. Sukumaran, 2021-03-25 Bone Marrow transplantation or Hematopoietic stem cell transplantation is a life saving procedure in a number of diseases,hematological and non hematological, which fail alternative medical management or have no other treatment options. It has transformed the lives of thousands of patients and their families around the world battling with fatal or debilitating diseases.There are many unique aspects of bone marrow transplantation which makes it very different from solid organ transplants. There is an enormous amount of research going on in this field both at clinical and basic science levels.With the rapidly changing world and field of transplantation, there is a need for an authoritative and up to date resource for transplant professionals. This book titled Contemporary Bone Marrow Transplantation aims to be a reference text comprehensively covering various facets of hematopoietic stem cell transplants with latest insights about the technique and basic science behind it . The book is the product of collective effort of transplant professionals round the world, and will reflect their experience as well as the current standard of care practices in Stem cell transplantation.The book will be divided into different sections focusing on the basic science of bone marrow transplant, the technical aspects of the procedure itself and the supportive care of transplant patients.There will also be a section each on epidemiology, upcoming trends and also case studies , which will discuss real case scenarios from the experience of the authors, to illustrate the practical challenges in managing bone marrow transplant recipients. |
| clinimacs prodigy user manual pdf: Current Strategies in Cancer Gene Therapy Wolfgang Walther, 2017-01-17 This book describes important developments and emerging trends in experimental and clinical cancer gene therapy. It reflects the tremendous advances made over recent years with respect to immunogenes, suicide genes and gene correction therapies, as well as in gene suppression and miRNA therapies. Many of the described strategies focus on the generation of more efficient and specific means of attack at known and novel cellular targets associated with tumor development and progression. The book also details parallel improvements in vector design, vector delivery, and therapeutic efficacy. It offers readers a stimulating, broad overview of advances in the field, linking experimental strategies to their clinical applications. |
| clinimacs prodigy user manual pdf: Biopharmaceutical Processing Gunter Jagschies, Eva Lindskog, Karol Lacki, Parrish M. Galliher, 2018-01-18 Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry. The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related to downstream purification and upstream processing fields. Economic considerations are included throughout, with recommendations for lowering costs and improving efficiencies. Designed for quick reference and easy accessibility of facts, calculations and guidelines, this book is an essential tool for industrial scientists and managers in the biopharmaceutical industry. - Offers a comprehensive, go-to reference for daily work decisions - Covers both upstream and downstream processes - Includes case studies that emphasize financial outcomes - Presents summaries, decision grids, graphs and overviews for quick reference |
| clinimacs prodigy user manual pdf: Methods in cell therapy and regenerative medicine Anna Lange-Consiglio, Charlotte Riviere, V. Prasad Shastri, Amiq Gazdhar, 2023-03-27 |
| clinimacs prodigy user manual pdf: Bringing Advanced Therapy Medicinal Products (ATMPs) to the Clinic and Beyond: How to Ensure the Sustainable and Affordable Introduction of ATMPs Into Healthcare Hans-Dieter Volk, Annelise Bennaceur Griscelli, Manuela Battaglia, Nuno M. Neves, 2022-11-30 |
| clinimacs prodigy user manual pdf: Tumor Immunology and Immunotherapy - Cellular Methods Part A , 2020-01-17 Tumor Immunology and Immunotherapy - Cellular Methods Part A, Volume 631, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New chapters include Detection of intracellular cytokine production by T cells with flow cytometry, High-throughput identification of human antigen-specific CD8+ and CD4+ T cells using soluble pMHC multimers, In vitro assays for effector T cell functions and activity of immunostimulatory antibodies, Ex vivo energetic profiling of tumor cells and T cells from mouse models and human samples, A cytofluorimetric assay to evaluate T cell polyfunctionality, and much more. |
| clinimacs prodigy user manual pdf: Immunotherapy – A Novel Facet of Modern Therapeutics Sujata P. Sawarkar, Vandana S. Nikam, Shariq Syed, 2020-12-16 This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics. Focusing on the application of immunotherapy in oncology, neurodegenerative and autoimmune diseases, it discusses the drug delivery systems, and pre-clinical and clinical methodologies for immunotherapy-based drugs. It also comprehensively reviews various aspects of immunotherapy, such as regulatory affairs, quality control, safety, and pharmacovigilance. Further, the book discusses the in vitro validation of therapeutic strategies prior to patient application and management of immunotherapy-related side effects and presents case studies demonstrating the design and development (pre-clinical to clinical) of immunotherapy for various diseases. It also describes various design considerations and the scale-up synthesis of immunotherapeutics and screening methods. Lastly, it explores the important aspect of cost-effectiveness and rational immunotherapy strategies. |
| clinimacs prodigy user manual pdf: Chimeric Antigen Receptor T Cells Kamilla Swiech, Kelen Cristina Ribeiro Malmegrim, Virgínia Picanço-Castro, 2020-11-24 This volume provides comprehensive methods from expert scientists working in the Chimeric Antigen Receptor T Cell (CAR-T Cell) field. Chapters guide readers through the state-of-art of CAR-T cell technology, CAR design and vector production, CAR-T cell generation and manufacturing, CAR-T cell characterization, and quality control. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Chimeric Antigen Receptor T Cells: Development and Production aims to be useful in the production of CAR-T cells, especially for therapeutic purposes. |
| clinimacs prodigy user manual pdf: Current Applications of Pharmaceutical Biotechnology Ana Catarina Silva, João Nuno Moreira, José Manuel Sousa Lobo, Hugo Almeida, 2020-02-06 This book offers an authoritative review of biopharmaceuticals and their clinical relevance. Biopharmaceuticals have been showing high therapeutic potential by means of biological and biosimilar medicines, particularly for the treatment of cancer, chronic diseases (e.g. diabetes, Crohn's disease, psoriasis and rheumatoid arthritis), neurodegenerative disorders (e.g. multiple sclerosis), and they have also been contributing to the progress of innovative therapies such as assisted reproductive medicine. Since the eighties, several biopharmaceuticals have been approved and, due to patents expiration, many biosimilars are also marketed. In this book, readers will find the most relevant updated information about the main clinical applications of pharmaceutical biotechnology. The authors provide expert analysis about the industrial challenges of recombinant proteins and the different classes of biopharmaceuticals, including monoclonal antibodies, vaccines, growth factors and stem cells. Topics such as bioprinting technologies in tissue engineering, gene therapy and personalized medicine are also covered in this book. Professionals, students and researchers interested in this field will find this work an important account. |
| clinimacs prodigy user manual pdf: Advancing Healthcare Through Personalized Medicine Priya Hays, 2021-09-27 This book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it helps to mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to the underlying concepts at the heart of personalized medicine. An innovative second edition, this book functions as an update to the successful first edition to include new, state-of-the-art information and advancements in the fast-paced field of personalized medicine. Chapters examine pharmacogenomics, targeted therapies, individualized diagnosis and treatment, and cancer immunotherapies. The book also features an essential discussion on how the advent of genomic technologies gives clinicians the capability to predict and diagnose disease more efficiently and offers a detailed up-to-date compilation of clinical trials in cancer leading to breakthrough therapies. The book also addresses the impact of Big Data on personalized medicine and the newfound applications of digital health and artificial intelligence. A work that advocates for a patient-centered approach, Advancing Healthcare Through Personalized Medicine, Second Edition is an invaluable text for clinicians, healthcare providers, and patients. |
| clinimacs prodigy user manual pdf: Gene and Cellular Immunotherapy for Cancer Armin Ghobadi, John F. DiPersio, 2022-01-01 Clinical and preclinical exploration of gene and cellular immunotherapy have seen rapid growth and interest with the development and approval of five Chimeric Antigen Receptor T-cell (CAR-T) products for lymphoma and myeloma and one Bispecific T-Cell Engager (BiTE) for acute lymphoblastic leukemia (ALL). These advances have dramatically improved the management of patients with relapsed refractory lymphoma, myeloma and leukemia. Gene and Cellular Immunotherapy for Cancer offers readers a comprehensive review of current cellular and gene-based immunotherapies. Divided into eighteen cohesive chapters, this book provides an in-depth and detailed look into cellular-based immunotherapies including CAR-T, TCR-T, TIL, Viral CTLs, NK cells in addition to T/NK cell engagers, focusing on their historical perspectives, biology, development and manufacturing, toxicities and more. Edited by two leading experts on gene and cellular immunotherapy, the book will feature chapters written by a diverse collection of recognized and up-and-coming experts and researchers in the field, providing oncologists, immunologists, researchers and clinical and basic science trainees with a bench to bedside view of the latest developments in the field. |
| clinimacs prodigy user manual pdf: Engineering Technologies and Clinical Translation Mansoor M. Amiji, Lara Scheherazade Milane, 2021-08-25 Engineering Technologies and Clinical Translation: Volume 3: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies, focusing specifically on the development of solutions for drug delivery and its clinical outcomes. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. This volume of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy discusses biomaterial, microfluidic, and biodegradable devices, engineered microbes, personalized medicine, clinical approval process, and many other IO technologies. Engineering Technologies and Clinical Translation: Volume 3: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. - Explores engineering technologies and their clinical translation in a comprehensive way - Presents forecasting on the future of nanotechnology and drug delivery for IO - Engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side |
| clinimacs prodigy user manual pdf: The Palgrave Handbook of Servitization Marko Kohtamäki, Tim Baines, Rodrigo Rabetino, Ali Ziaee Bigdeli, Christian Kowalkowski, Rogelio Oliva, Vinit Parida, 2021-07-26 Manufacturers have shifted their focus from products to smart solutions in search of higher returns and additional growth opportunities. This shift, described as servitization, or lately as a digital servitization, is not a simple process. Academic study has revealed that its issues are complex, problematic, contingent, and even paradoxical, involving multiple organizational layers, such as operations, strategic, relational, and even ecosystemic layers. Recent literature studies have called for improved theories in servitization, and even alternative narratives. In this handbook, the chapters take different perspectives towards servitization, digital servitization or Product-Service-Software systems, presenting and debating over concepts such as organizational transformation, change management, strategic management, business models, innovation and product-service operations. The handbook provides an opportunity to develop improved theoretical grounds for servitization, and thus to elaborate and develop the field further. This volume will be of great interest for the servitization community, including scholars, Ph.D. and master students, but also company managers, developers and consultants facilitating company’s servitization efforts. |
| clinimacs prodigy user manual pdf: Stem Cells in Clinical Practice and Tissue Engineering Rakesh Sharma, 2018-05-02 Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status. |
| clinimacs prodigy user manual pdf: Pediatric Neuro-oncology Katrin Scheinemann, |
| clinimacs prodigy user manual pdf: Single-Use Technology in Biopharmaceutical Manufacture Regine Eibl, Dieter Eibl, 2019-07-18 Authoritative guide to the principles, characteristics, engineering aspects, economics, and applications of disposables in the manufacture of biopharmaceuticals The revised and updated second edition of Single-Use Technology in Biopharmaceutical Manufacture offers a comprehensive examination of the most-commonly used disposables in the manufacture of biopharmaceuticals. The authors—noted experts on the topic—provide the essential information on the principles, characteristics, engineering aspects, economics, and applications. This authoritative guide contains the basic knowledge and information about disposable equipment. The author also discusses biopharmaceuticals’ applications through the lens of case studies that clearly illustrate the role of manufacturing, quality assurance, and environmental influences. This updated second edition revises existing information with recent developments that have taken place since the first edition was published. The book also presents the latest advances in the field of single-use technology and explores topics including applying single-use devices for microorganisms, human mesenchymal stem cells, and T-cells. This important book: • Contains an updated and end-to-end view of the development and manufacturing of single-use biologics • Helps in the identification of appropriate disposables and relevant vendors • Offers illustrative case studies that examine manufacturing, quality assurance, and environmental influences • Includes updated coverage on cross-functional/transversal dependencies, significant improvements made by suppliers, and the successful application of the single-use technologies Written for biopharmaceutical manufacturers, process developers, and biological and chemical engineers, Single-Use Technology in Biopharmaceutical Manufacture, 2nd Edition provides the information needed for professionals to come to an easier decision for or against disposable alternatives and to choose the appropriate system. |
| clinimacs prodigy user manual pdf: Cell Therapy Adrian Gee, 2009-09-18 Cell Therapy: cGMP Facilities and Manufacturing is the source for a complete discussion of facility design and operation with practical approaches to a variety of day-to-day activities, such as staff training and competency, cleaning procedures, and environmental monitoring. This in-depth book also includes detailed reviews of quality, the framework of regulations, and professional standards. It meets a previously unmet need for a thorough facility-focused resource, Cell Therapy: cGMP Facilities and Manufacturing will be an important addition to the cell therapy professional’s library. Additional topics in Cell Therapy: cGMP Facilities and Manufacturing...Standard operating procedures - Supply management - Facility equipment - Product manufacturing, review, release and administration - Facility master file. |
| clinimacs prodigy user manual pdf: Bone Marrow Processing and Purging Adrian P. Gee, 2020-11-25 Bone Marrow Processing and Purging: A Practical Guide provides an up-to-date practical guide to the major ex vivo procedures associated with bone marrow transplantation. Previously, this information was communicated primarily by word of mouth; now experts in the field present detailed descriptions and evaluations of methods for marrow harvesting, evaluation (including tumor infiltration, flow cytometric analysis, and colony assays), comparative methods for automated nucleated cell separation and enumeration, tumor cell purging, T cell depletion, stem cell selection, gene transfer, and cytopreservation. Special sections address quality control and FDA regulations. The book provides a unique information source intended for clinicians, researchers, technical staff, transplant nurses, and medical students involved in this rapidly expanding area of medicine. |
| clinimacs prodigy user manual pdf: Adoptive Immunotherapy Burkhard Ludewig, Matthias W. Hoffmann, 2008-02-02 An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients. Taking advantage of the latest technologies, the authors present readily reproducible experimental protocols for the study of dendritic cells, T cells, monoclonal antibodies, and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on the progress of selected approaches in clinical trials. Additional chapters cover the molecular definition of target antigens, mathematical modeling approaches to immunotherapy, and the utilization of regulatory T cells. The protocols make it possible to study the adoptive transfer of tailored antigen-specific immune cells and to improve the clinical application of adoptive immunotherapy. |
| clinimacs prodigy user manual pdf: Chimeric Antigen Receptor T-Cell Therapies for Cancer E-Book Daniel W. Lee, Nirali N. Shah, 2019-11-30 From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali N. Shah, this clinical resource keeps you up to date on the latest developments in this rapidly evolving area. - Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging therapy, post-CAR monitoring, and multidisciplinary approaches to supportive care. - Includes key topics on associated toxicities such as predictive biomarkers, infections, and multidisciplinary approaches to supportive care. - Presents current knowledge on FDA approved CAR T-cell products as well as developments on the horizon. - Editors and authors represent leading investigators in academia and worldwide pioneers of CAR therapy. |
| clinimacs prodigy user manual pdf: The BMT Data Book Reinhold Munker, Hillard M. Lazarus, Kerry Atkinson, 2009-02-26 An essential guide to the data, outcome studies and complex decision-making processes involved in blood and marrow stem cell transplantation. |
| clinimacs prodigy user manual pdf: Translational Regenerative Medicine Anthony Atala, Julie Allickson, 2014-12-01 Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. - Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications - Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system - Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine |
| clinimacs prodigy user manual pdf: Human Cytomegalovirus Thomas E. Shenk, Mark F. Stinski, 2008-05-09 This volume has gathered some of the experts in the field to review aspects of our understanding of CMV and to offer perspectives of the current problems associated with CMV. The editors and authors hope that the chapters will lead to a better understanding of the virus that will assist in the development of new and unique antivirals, a protective vaccine, and a full understanding of CMV's involvement in human disease. |
| clinimacs prodigy user manual pdf: Second Generation Cell and Gene-Based Therapies Alain Vertes, Nathan J. Dowden, Devyn Smith, Nasib Qureshi, 2020-02-07 Second Generation Cell and Gene-Based Therapies: Biological Advances, Clinical Outcomes, and Strategies for Capitalisation serves as the only volume to the market to bridge basic science, clinical therapy, technology development, and business in the field of cellular therapy/cytotherapy. After more than two decades of painstaking fundamental research, the concept of therapeutic cells (stem cells, genes, etc.), beyond the concept of vaccines, is reaching clinical trial, with mounting confidence in the safety and efficacy of these products. Nonetheless, numerous incremental technical advances remain to be achieved. Thus, this volume highlights the possible R&D paths, which will ultimately facilitate clinical delivery of cutting edge curative products.The next waves of innovation are reviewed in depth for hematopoietic stem cells, mesenchymal stem cells, tissue engineering, CAR-T cells, and cells of the immune system, as well as for enabling technologies such as gene and genome editing. Additionally, deep dives in product fundamentals, history of science, pathobiology of diseases, scientific and technological bases, and financing and technology adoption constraints are taken to unravel what will shape the cytotherapy industry to the horizon 2025 and beyond. The outcome is not simply a scientific book, but a global perspective on the nascent field combining science, business, and strategic fundamentals. - Helps readers learn about the most current trends in cell-based therapy, their overall effectiveness from a clinical prospective, and how the industry is moving therapies forward for capitalization - Perspectives section at the end of each chapter summarizes key learnings, hypotheses, and objectives highlighted and combines scientific and business insights - Edited and authored by scientists representing both basic and clinical research and industry, presenting a complete story of the current state and future promise of cellular therapies |
| clinimacs prodigy user manual pdf: Stem Cell Manufacturing Joaquim M.S. Cabral, Claudia Lobato da Silva, Lucas G. Chase, M. Margardia Diogo, 2016-07-24 Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the patients. Fully defined cellular products can be used to restore the structure and function of damaged tissues and organs and to develop stem cell-based cellular therapies for the treatment of cancer and hematological disorders, autoimmune and other inflammatory diseases and genetic disorders. - Presents the first 'Flowchart' of stem cell manufacturing enabling easy understanding of the various processes in a sequential and coherent manner - Covers all bioprocess technologies required for the transfer of the bench findings to the clinic including the process components: cell signals, bioreactors, modeling, automation, safety, etc. - Presents comprehensive coverage of a true multidisciplinary topic by bringing together specialists in their particular area - Provides the basics of the processes and identifies the issues to be resolved for large scale cell culture by the bioengineer - Addresses the critical need in bioprocessing for the successful delivery of stem cell technology to the market place by involving professional engineers in sections of the book |
| clinimacs prodigy user manual pdf: Ex Vivo Cell Therapy Klaus Schindhelm, Robert Nordon, 1999 R.E. Nordon and K. Schindhelm, Introduction. -- L. Robb, A.G. Elefanty, and C.G. Begley, Transcriptional Control of Hematopoieses. -- R. Starr and N.A. Nicola, Cell Signaling by Hemopoietic Growth Factor Receptors. -- P.J. Simmons, D.N. Haylock, and J.-P. Lévesque, Influence of Cytokines and Adhesion Molecules on Hematopoietic Stem Cell Development. -- P.A. Rowlings, Allogeneic Hematopoietic Stem Cell Transplantation. -- U. Hahn and L.B. To, Autologous Stem Cell Transplantation. -- M.R. Vowels, Cord Blood Stem Cell Transplantation. -- S.R. Riddell, E.H. Warren, D. Lewinsohn, C. Yee, and P.D. Greenberg, Reconstitution of Immunity by Adoptive Immunotherapy with T Cells. -- L.Q. Sun, M. Miller, and G. Symonds, Exogenous Gene Transfer into Lymphoid and Hematopoietic Progenitor Cells. -- C. Dowding, T. Leemhuis, A. Jakubowski, and C. Reading, Process Development for Ex Vivo Cell Therapy. -- R.E. Nordon and K. Schindhelm, Cell Separation. -- P.W. Zandstra, C.J. Eaves, and J.M. Piret, Environ ... |
| clinimacs prodigy user manual pdf: Pharmaceutical Biotechnology Daan J. A. Crommelin, Robert D. Sindelar, 2002-11-14 The field of pharmaceutical biotechnology is evolving rapidly. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for cancer, viral infections, cardiovascular and hereditary disorders, and other diseases. In addition, scientists are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. This introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use. Pharmaceutical Biotechnology serves as a complete one-stop source for undergraduate pharmacists, and it is valuable for researchers and professionals in the pharmaceutical industry as well. |
| clinimacs prodigy user manual pdf: Molecular Microbiology David H. Persing, Fred C. Tenover, Randall T. Hayden, Margareta Ieven, Melissa B. Miller, Frederick S. Nolte, Yi-Wei Tang, Alex van Belkum, 2020-07-24 Presenting the latest molecular diagnostic techniques in one comprehensive volume The molecular diagnostics landscape has changed dramatically since the last edition of Molecular Microbiology: Diagnostic Principles and Practice in 2011. With the spread of molecular testing and the development of new technologies and their opportunities, laboratory professionals and physicians more than ever need a resource to help them navigate this rapidly evolving field. Editors David Persing and Fred Tenover have brought together a team of experienced researchers and diagnosticians to update this third edition comprehensively, to present the latest developments in molecular diagnostics in the support of clinical care and of basic and clinical research, including next-generation sequencing and whole-genome analysis. These updates are provided in an easy-to-read format and supported by a broad range of practical advice, such as determining the appropriate type and quantity of a specimen, releasing and concentrating the targets, and eliminating inhibitors. Molecular Microbiology: Diagnostic Principles and Practice Presents the latest basic scientific theory underlying molecular diagnostics Offers tested and proven applications of molecular diagnostics for the diagnosis of infectious diseases, including point-of-care testing Illustrates and summarizes key concepts and techniques with detailed figures and tables Discusses emerging technologies, including the use of molecular typing methods for real-time tracking of infectious outbreaks and antibiotic resistance Advises on the latest quality control and quality assurance measures Explores the increasing opportunities and capabilities of information technology Molecular Microbiology: Diagnostic Principles and Practice is a textbook for molecular diagnostics courses that can also be used by anyone involved with diagnostic test selection and interpretation. It is also a useful reference for laboratories and as a continuing education resource for physicians. If you are looking for online access to the latest clinical microbiology content, please visit www.wiley.com/learn/clinmicronow. |
| clinimacs prodigy user manual pdf: Magnetic Techniques for the Treatment of Materials Jan Svoboda, 2007-05-08 This book reflects changes that have occurred during the last two decades in theoretical understanding and practical implementation of magnetic techniques in materials treatment. Research and development needs, based on the current strategic thinking and on principles of sustainable development are outlined. Development of magnetic separators based on powerful permanent magnetic materials, construction of reliable superconducting separators, design of efficient eddy-current separators and industrial implementation of magnetic carriers and magnetic fluids are examples of innovative changes that have taken place during the last twenty years. The book reflects the current technological trends and re-positions the research, development and practice of magnetic methods of material treatment in such areas as minerals beneficiation, recycling, waste treatment and biomedical and clinical applications. |
| clinimacs prodigy user manual pdf: Microtechnology for Cell Manipulation and Sorting Wonhee Lee, Peter Tseng, Dino Di Carlo, 2016-10-05 This book delves into the recent developments in the microscale and microfluidic technologies that allow manipulation at the single and cell aggregate level. Expert authors review the dominant mechanisms that manipulate and sort biological structures, making this a state-of-the-art overview of conventional cell sorting techniques, the principles of microfluidics, and of microfluidic devices. All chapters highlight the benefits and drawbacks of each technique they discuss, which include magnetic, electrical, optical, acoustic, gravity/sedimentation, inertial, deformability, and aqueous two-phase systems as the dominant mechanisms utilized by microfluidic devices to handle biological samples. Each chapter explains the physics of the mechanism at work, and reviews common geometries and devices to help readers decide the type of style of device required for various applications. This book is appropriate for graduate-level biomedical engineering and analytical chemistry students, as well as engineers and scientists working in the biotechnology industry. |
| clinimacs prodigy user manual pdf: Immunotherapy in Translational Cancer Research Laurence J. N. Cooper, Elizabeth A. Mittendorf, Judy Moyes, Sabitha Prabhakaran, 2018-05-01 A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues. Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and: Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapy Explores the breath of treatments that reflect the complexity of the immune system itself Includes contributions from a panel international experts in the field of immunotherapy Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research. |
| clinimacs prodigy user manual pdf: Successes and Challenges of NK Immunotherapy Benjamin Bonavida, Anahid Jewett, 2021-06-23 Successes and Challenges of NK Immunotherapy: Increasing Anti-tumor Efficacy describes the unique therapeutic applications of NK cells to fight cancers and eliminate the bulk and subset of cancer stem cells responsible for metastasis, relapse and recurrences. The book provides information on the development, engineering, mechanisms of action, response to various preclinical models, and applications in various clinical trials. Sections cover the development of highly engineered cytotoxic NK cells, their mechanisms of action, preclinical and clinical applications, the development and application of CAR-NK cells, and new NK-drug conjugates, also emphasizing that activated NK cells can target and kill highly resistant cancer stem cells. Written by the leading experts on NK immunotherapy worldwide, this is a valuable resource for researchers, clinicians and members of the biomedical field who are interested in understanding novel and efficient therapies to fight cancers. - Discusses the unique developmental applications of NK immunotherapy against cancers, which differs greatly from other types of immunotherapies - Provides up-to-date and highly relevant information through chapters written by the leading researchers in the field - Presents a significant number of schematic diagrams for easy understanding and reproducibility |
| clinimacs prodigy user manual pdf: Haploidentical Transplantation Stefan O. Ciurea, Rupert Handgretinger, 2018-05-03 In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty. |
| clinimacs prodigy user manual pdf: T-Helper Cells Francesco Annunziato, Laura Maggi, Alessio Mazzoni, 2021-04-30 The aim of this volume is to provide a comprehensive description of methods and protocols useful for the further study of T-helper cells. Chapters guide readers through T-helper cell recovery, molecular study, signal transduction pathways, T-cell manipulation and, last but not least, “omic” approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, T- Helper Cells: Methods and Protocols aims to be a useful practical guide to researches to help further their study in this field. |
| clinimacs prodigy user manual pdf: Oncoimmunology Laurence Zitvogel, Guido Kroemer, 2017-12-13 In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field. |
| clinimacs prodigy user manual pdf: Decision Making in Systems Engineering and Management Gregory S. Parnell, Patrick J. Driscoll, Dale L. Henderson, 2011-03-16 Decision Making in Systems Engineering and Management is a comprehensive textbook that provides a logical process and analytical techniques for fact-based decision making for the most challenging systems problems. Grounded in systems thinking and based on sound systems engineering principles, the systems decisions process (SDP) leverages multiple objective decision analysis, multiple attribute value theory, and value-focused thinking to define the problem, measure stakeholder value, design creative solutions, explore the decision trade off space in the presence of uncertainty, and structure successful solution implementation. In addition to classical systems engineering problems, this approach has been successfully applied to a wide range of challenges including personnel recruiting, retention, and management; strategic policy analysis; facilities design and management; resource allocation; information assurance; security systems design; and other settings whose structure can be conceptualized as a system. |
| clinimacs prodigy user manual pdf: NK Cells in Cancer Immunotherapy: Successes and Challenges Anahid Jewett, Yuman Fong, 2022-12-06 NK Cells in Cancer Immunotherapy: Successes and Challenges explains the latest immunotherapeutic strategies, focusing on NK cells to allow the best and precise combination treatments to cancer patients. The book provides existing background knowledge in the field of immunotherapy and discusses future areas of research required to carry out cutting-edge, validated therapies. Chapters cover advances in immunotherapeutic strategies, in particular, the use of NK cells with and without T-cell therapy in the treatment of cancer. The book is a valuable resource for cancer researchers, oncologists, graduate students and those interested in learning more about novel strategies to treat cancer patients. Immunotherapy is fast becoming the method of choice for cancer therapy. Although remarkable advances have been made in the field of immunotherapy, there are significant challenges and difficulties ahead since many of the current immunotherapeutic strategies do not provide long-lasting treatment strategies, and therefore are not very effective. - Covers CAR/T and CAR/NK and adoptive NK cell therapy with and without T cell therapies - Discusses basic biology of NK cells and mouse models of human cancers and the role of NK cells in metastatic cancer and in cancer stem cells - Encompasses information on combination therapies using check point inhibition, adoptive transfer of cytotoxic effector cells, chemotherapeutic drugs and activating and inhibitory antibodies |
CliniMACS® Plus Instrument | Miltenyi Biotec | USA
The CliniMACS CD34 Reagent System is a medical device that enables in vitro enrichment of CD34-positive hematopoietic stem cells for graft-versus-host disease (GVHD) prophylaxis in …
CliniMACS® Plus System - Miltenyi Biotec
The CliniMACS Plus System is an integral part of the clinical workflow due to its uniqueness in offering cell separation in a closed and sterile environment using an automated, magnetic …
GMP cell therapy manufacturing | CliniMACS Prodigy®
The CliniMACS Prodigy sets a new standard in automated cell manufacturing with advanced integrated solutions to streamline cell processing workflows – from cell separation through cell …
CliniMACS Prodigy® Instrument - Miltenyi Biotec
The CliniMACS Prodigy® represents the next generation in automated cell processing. This device offers advanced integrated solutions to streamline cell processing workflows – from cell …
CliniMACS CD34 Reagent System - FDA
The CliniMACS CD34 Reagent System is indicated for processing hematopoietic progenitor cells collected by apheresis (HPC, Apheresis) from an allogeneic, HLA-identical, sibling donor to …
Cell Based Therapy Laboratory - Children's Hospital of Philadelphia
Manufacturing of CAR-T cells and virus-specific T cells with the CliniMACS Prodigy We also collaborate with investigators across CHOP to develop cGMP-compliant manufacturing …
Cost-Effective Manufacture and Promising Initial Efficacy of …
Nov 5, 2024 · Use of the CliniMACS Prodigy platform allows for GMP, rapid, semi-automated, clinical-scale processing of humanized (hu)CART19 cell products in a point-of-care system …
CliniMACS Prodigy® Platform - Miltenyi Biotec
CliniMACS PBS/EDTA Buffer, is FDA approved as a Humanitarian Use Device (HUD), authorized by U.S. Federal law for use in the treatment of patients with acute myeloid leukemia (AML) in …
Cell & gene manufacturing | CliniMACS Cell Factory®
The CliniMACS Cell Factory brings clinical-scale cell manufacturing to the next level. Our scalable, automated, and closed-system cell processing platform reduces cleanroom …
Cell enrichment | Cell depletion | Clinical-scale | CliniMACS® Plus ...
Automated and robust cell separation is key for successful cell and gene therapy (CGT). With a track record of over 25 years, The CliniMACS® Plus System represents a cornerstone in …
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User-friendly software We designed the Cocoon ® Platform interface and software to make work easier. Our state-of-the-art software is user-friendly and editable for simple on-site …
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CliniMACS Prodigy TS 620 1 piece CliniMACS PBS/EDTA Buffer (3 L) 1 piece TexMACS™ GMP Medium 5×2 L bags MACS GMP Recombinant Human IL-7 and IL-15 ... responsibility of the …
Clinical NK cell - Miltenyi Biotec
system, with minimal hands-on time from the user. The standardized procedure enables robust and consistent results. CliniMACS Prodigy® CD3/CD56 System The CliniMACS Prodigy …
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CliniMACS® Specification Sheet - Miltenyi Biotec
In the US, the CliniMACS CD34 Reagent System, including the CliniMACS Plus Instrument, CliniMACS CD34 Reagent, CliniMACS Tubing Sets TS and LS, and the CliniMACS PBS/EDTA …
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The CliniMACS Prodigy® Platform - Miltenyi Biotec
The CliniMACS Prodigy Platform Figure 1: With the modular CliniMACS® Electroporator and CliniMACS Formulation Unit, the CliniMACS Prodigy Platform automates the entire cell …
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corresponding CliniMACS Prodigy User Manual. The performance of the system relies on usage of components free of RNAse and DNAse. This product is tested to be free of RNAse and …
PRODIGY.MP Manual - DirectOut
Prodigy.MP Manual - Version 2.5 page 7 of 142 About This Manual About This Manual How to Use This Manual This manual guides you through the installation and operation of the device. …
Poster ID: P0425
transduction experiments on the CliniMACS Prodigy were per-formed in parallel. The transduction with CD19 CAR vector at MOI 30 resulted in comparable cell recovery and viability be-tween …
CliniMACS® Plus System - Miltenyi Biotec
CliniMACS® Plus System Automated clinical-scale cell isolation Tried and tested for more than 25 years, the CliniMACS Plus System is continuously facilitating high quality cell separation. …
CliniMACS Prodigy® Supplementary Bag - Miltenyi Biotec
CliniMACS Prodigy® Supplementary Bag Miltenyi Biotec B.V. & Co. KG Friedrich-Ebert-Straße 68 51429 Bergisch Gladbach | Germany +49 2204 8306-3803 CliniMACS Prodigy Supplementary …
MACS GM Cell TrnsAct™ re Scle CRGMP - Miltenyi Biotec
CliniMACS® Prodigy TS 620 (CR) 170-076-620 MACS GMP® T Cell TransAct™ – Large Scale CR/GMP 200-076-204 ... Cell Transduction - Large Scale User manual for more information. …
User manual for CliniMACS Prodigy (CE), Czech
4.1.1 CliniMACS Prodigy v systému pro separaci buněk CliniMACS Prodigy 40 4.1.2 CliniMACS Prodigy v rámci Systému CliniMACS Prodigy Cell & Gene Therapy Manufacturing System 41 …
User manual for CliniMACS Plus Applications (CE), software …
Applications CliniMACS® Plus Manuel d'utilisation Logiciel version 2.4x Édition: 2023-02 210-003-234/01 Miltenyi Biotec B.V. & Co. KG Friedrich-Ebert-Straße 68
Owner’s Manual - Prodigy Diabetes Care
Nov 18, 2013 · PRODIGY Voice® Blood Glucose Meter Owner’s Manual 2 Dear Prodigy® Meter Owner: Thank you for choosing the Prodigy Voice® meter as your blood glucose monitoring …
CliniMACS Prodigy® Adherent Cell Culture System GMP …
The CliniMACS Prodigy® Adherent Cell Culture System allows GMP-compliant and clinical scale human ... (3.8×10⁸) compared to manual handling (4.5×10⁸). ... any clinical application of the …
T Cell TransAct - Miltenyi Biotec
on the CliniMACS Prodigy after polyclonal stimulation with MACS GMP T Cell TransAct, standard or Large Scale. Either the standard-scale chamber (black, n=4) or the large-scale chamber …
User manual for CliniMACS Prodigy (CE), Greek
CliniMACS Prodigy® Εγχειρίδιο χρήσης Eκδοθείς: 2022-08 210-003-283/01 Miltenyi Biotec B.V. & Co. KG Friedrich-Ebert-Straße 68
CliniMACS® Cryo Supplement, 3× - Miltenyi Biotec
Instructions for use Refer to the corresponding CliniMACS Prodigy User Manual for the validated combinations of CliniMACS Reagents, application processes, tubing sets, and buffers/media. …
CliniMACS® Formulation Unit - Miltenyi Biotec
CliniMACS Formulation Unit Two possible connection sites Figure 3: CliniMACS Formulation Solution and Cryo Supplement come in one liter bags and can be sterile-connected to your …
Final formulation and filling of engineered cells - Miltenyi Biotec
The CliniMACS Prodigy® in combination with the CliniMACS® Formulation Unit allows the final formulation and filling of engineered T cells. This application sheet provides an overview of the …
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corresponding CliniMACS User Manual. Handling instructions The use of the product is described in the corresponding user manual of the chosen application. Refer to the CliniMACS User …
User manual for CliniMACS Prodigy (CE), Finnish
CliniMACS Prodigy® Käyttäjän Opas Myönnetty: 2022-06 210-003-280/01 Miltenyi Biotec B.V. & Co. KG Friedrich-Ebert-Straße 68 51429 Bergisch Gladbach
Title page Automated manufacturing of CAR-T cells for …
CliniMACS Prodigy Running Title (max 50 characters): ... Programming flexibility incorporates an “activity matrix” that is user-defined and determines the chronological order of different …
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User manual for CliniMACS Prodigy (CE), Russian
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MACS GM Cell TrnsAct™ are cle, CR - Miltenyi Biotec
enrichment by the CliniMACS Prodigy T Cell Transduction - Large Scale process. Refer to CliniMACS Prodigy T Cell Transduction - Large Scale User manual for more information. 4.3.2 …
Regulatory T cell research - Miltenyi Biotec
blood and blood components") - must be followed. Thus, any clinical application of the target cells is exclusively within the responsibility of the user of a CliniMACS System. In the US, the …
Carola Barth, Daniela Gudert, Alexander Bohn, Sophia Lollies, …
the CliniMACS Prodigy® TCT application and allows the cultivation and expansion of higher cell numbers by using a larger cell preparation and cultivation unit. Taken together, the automated …
Sepax C-Pro Cell Processing Instrument - Cytiva
Compact design and user-friendly interface to minimize your space and resource requirements • Maintain flexibility. Sepax C-Pro is a multipurpose solution ... Data management with PDF …
gene-engineered HSCs manufactured by the CliniMACS …
specification, and the CliniMACS Prodigy HSC Engineering process are provided in the application sheet “Generation of gene-engineered hematopoietic stem cells” (# 130-126-605) …
MACS TubeSealer User Manual (CE), German - Miltenyi Biotec
des CliniMACS Prodigy, zu speziellen Anwendungen auf dem CliniMACS Prodigy oder weitere Informationen, Warnhinweise sowie Vorsichtsmaßnahmen bezüglich des Betriebs des …
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( 12 ) United States Patent
Now FDA approved — The CliniMACS CD34 Reagent System , Miltenyi Biotec , Retrieved from Internet : www . miltenyibiotec . com en / clinicalapplications / ip _ clinimacs _ system _ fda _ …
User manual for CliniMACS Prodigy (CE), Slovak - Miltenyi …
4.1.1 Prístroj CliniMACS Prodigy v rámci systému CliniMACS Prodigy na separáciu buniek 40 4.1.2 Prístroj CliniMACS Prodigy v rámci systému CliniMACS Prodigy na výrobu bunkových a …
Clinimacs Prodigy User Manual Pdf
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MACS TubeSealer User Manual (CE), English - Miltenyi Biotec
CliniMACS Prodigy, specific applications run on the CliniMACS Prodigy, or further information, warnings, and precautions regarding the operation of the CliniMACS Prodigy System, refer to …
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Miltenyi iotec mbH Friedrich-Ebert-Strae 68 142 Berisch Gladach, Germany Phone +4 20 306-0, ax +4 20 5197 macs@miltenyiiotec.de www.miltenyibiotec.com Miltenyi Biotec Inc. 2303 …
User manual for CliniMACS Prodigy (CE), Norwegian
4 CliniMACS Prodigy 39 4.1 Juridisk informasjon 39 4.1.1 CliniMACS Prodigy i CliniMACS Prodigy-celledelingssystem 40 4.1.2 CliniMACS Prodigy i CliniMACS Prodigy …
Generation of gene-engineered T cells T cell transduction …
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Development of an automated manufacturing process for …
process using the CliniMACS Prodigy for autologous T cell therapy products that can deliver a high number of cells suit-able for treating solid tumor indications and compatible with …
Protocol - The New England Journal of Medicine
Protocol Protocol for: Müller F, Taubmann J, Bucci L, et al. CD19 CAR T-cell therapy in autoimmune disease — a case series with follow-up. N Engl J Med 2024;390:687-700.
User manual for CliniMACS Prodigy (CE), Turkish - Miltenyi …
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The CliniMACS Prodigy® - ampk.kr
The CliniMACS Prodigy® automates cell processing from starting material to final cellular product in a single benchtop instrument. All major cell manufacturing steps are ... responsibility of the …
