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| excitation-contraction coupling diagram: Excitation-Contraction Coupling and Cardiac Contractile Force Donald Bers, 2001-08-31 How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation-Contraction Coupling and Cardiac Contractile Force – Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields. |
| excitation-contraction coupling diagram: Anatomy & Physiology Lindsay Biga, Devon Quick, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Matern, Katie Morrison-Graham, Jon Runyeon, 2019-09-26 A version of the OpenStax text |
| excitation-contraction coupling diagram: Nerve and Muscle R. D. Keynes, D. J. Aidley, 2001-03-15 Essential textbook for all undergraduate students of neurobiology, physiology, cell biology and preclinical medicine. |
| excitation-contraction coupling diagram: Keynes & Aidley's Nerve and Muscle Christopher L.-H. Huang, 2020-11-19 A complete, yet accessible and up-to-date, introduction to the cellular physiology of nerve, and skeletal, cardiac and smooth muscle. |
| excitation-contraction coupling diagram: Anatomy and Physiology J. Gordon Betts, Peter DeSaix, Jody E. Johnson, Oksana Korol, Dean H. Kruse, Brandon Poe, James A. Wise, Mark Womble, Kelly A. Young, 2013-04-25 |
| excitation-contraction coupling diagram: Functional Movement Development Across the Life Span Donna Joy Cech, Suzanne Tink Martin, 2011-09-06 Providing a solid foundation in the normal development of functional movement, Functional Movement Development Across the Life Span, 3rd Edition helps you recognize and understand movement disorders and effectively manage patients with abnormal motor function. It begins with coverage of basic theory, motor development and motor control, and evaluation of function, then discusses the body systems contributing to functional movement, and defines functional movement outcomes in terms of age, vital functions, posture and balance, locomotion, prehension, and health and illness. This edition includes more clinical examples and applications, and updates data relating to typical performance on standardized tests of balance. Written by physical therapy experts Donna J. Cech and Suzanne Tink Martin, this book provides evidence-based information and tools you need to understand functional movement and manage patients' functional skills throughout the life span. - Over 200 illustrations, tables, and special features clarify developmental concepts, address clinical implications, and summarize key points relating to clinical practice. - A focus on evidence-based information covers development changes across the life span and how they impact function. - A logical, easy-to-read format includes 15 chapters organized into three units covering basics, body systems, and age-related functional outcomes respectively. - Expanded integration of ICF (International Classification of Function) aligns learning and critical thinking with current health care models. - Additional clinical examples help you apply developmental information to clinical practice. - Expanded content on assessment of function now includes discussion of participation level standardized assessments and assessments of quality-of-life scales. - More concise information on the normal anatomy and physiology of each body system allows a sharper focus on development changes across the lifespan and how they impact function. |
| excitation-contraction coupling diagram: Sports-Specific Rehabilitation Robert A. Donatelli, PhD, PT, OCS, 2006-10-11 A comprehensive resource for focusing on returning injured athletes to their optimal performance! This book discusses exercise principles; muscle fatigue, muscle damage, and overtraining concepts; pathophysiology of overuse injuries; core evaluation in sports-specific testing; physiological basis of exercise specific to sport; and special considerations for the athlete. Secial features such as evidence-based clinical application boxes provide the reader with a solid body of research upon which to base their practice. Aligned to the Guide to Physical Therapy Practice to help learn how to work with athletes' injuries and help them make a physical comeback while following best practices. Incorporation of muscle physiology demonstrates it as the basis for athlete's exercise prescription. Coverage of pathophysiology of overuse injuries illustrates the damage to the musculoskeletal system. Inclusion of treatment and training approaches for athletic rehabilitation shows how to restore the musculoskeletal system back to full flexibility, strength, power, and endurance. Evidence-based clinical application boxes found throughout the book cite key studies and provide real-world application to a clinical setting. Extensive photographs show hands-on demonstrations of important rehabilitation techniques, helping the cinician to accurately apply them during treatment. |
| excitation-contraction coupling diagram: Colonic Motility Sushil K. Sarna, 2010-11-01 Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood. |
| excitation-contraction coupling diagram: Cardiovascular Physiology Concepts Richard E. Klabunde, 2020-12-01 Praised for its concise coverage, this highly accessible monograph lays a foundation for understanding the underlying concepts of normal cardiovascular function and offers a welcome alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Clear explanations, ample illustrations and engaging clinical cases and problems provide the perfect guidance for self-directed learning and prepare you to excel in clinical practice. |
| excitation-contraction coupling diagram: Encyclopedia of Exercise Medicine in Health and Disease Frank C. Mooren, 2012-04-19 The Encyclopedia of Exercise Medicine is intelligently structured, easy accessible and user-friendly: A-Z format, clear, concise language and uniform essay structure as well as extensive cross references between keywords and related articles enables efficient searches in a user-friendly manner both for experts and newcomers. It is intended to be a comprehensive up-to-date data base on the adaptation of the human body to exercise and on the therapeutic use of exercise with up to 2,000 keywords. It covers all aspects within the full range of modern exercise medicine of each particular scientific discipline (cancer, parasitology, aging, etc.). This includes information on methodological approaches to measuring the principle components of motor fitness, and practical aspects of their enhancement by trainings regimes as well as by nutrition and the application of drugs. Such a wide range of entries, all written by leading experts in their respective fields, will therefore address both the basic/clinical scientist as well as the practitioner. Moreover, the Encyclopedia of Exercise Medicine is aimed at people in related fields, health care professionals, physiotherapists, trainers, students, informed athletes and interested laypersons. It is available both in print and as a fully searchable and hyperlinked electronic online edition. |
| excitation-contraction coupling diagram: Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle George B. Frank, C. Paul Bianchi, Henk Keurs, 2012-12-06 The Third International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, organized by George Frank, C. Paul Bianchi, and Henk E. DJ. ter Keurs, was held in Banff Centre, Banff, Alberta, Canada during June 26 to June 30, 1991. The theme of these symposia has been to recognize the similarities and dissimilarities of excitation-contraction coupling in skeletal, cardiac, and smooth muscle. Cross fertilization of concepts of excitation-contraction coupling in these three types of muscle has occurred since the early studies in the late fifties and early sixties on skeletal muscle. Investigators in each field meet only at specialized symposia which exclude investigators in the other fields. The purpose of the symposia has been to bring together international investigators studying excitation-contraction coupling in skeletal, cardiac, and smooth muscle so that we may learn from each other and hence provide a more global concept of excitation-contraction. The Third International Symposia has accomplished its objective as we recognize that calcium channels of the sarcolemma and the sarcoplasmic reticulum play key essential roles in excitation-contraction coupling in all three types of muscles. In skeletal muscle the recognition that E-C coupling consists of two parallel mechanisms, one dependent upon a dihydropyridine voltage-sensitive sensors coupled to calcium release from the terminal cisternae via the ryanodine sensitive channel in the foot structure of the triad. |
| excitation-contraction coupling diagram: Core Topics in Cardiac Anesthesia Jonathan H. Mackay, Joseph E. Arrowsmith, 2012-03-15 Since the publication of the first edition of Core Topics in Cardiac Anaesthesia, the clinical landscape has undergone significant change. Recent developments include the increased use of electrophysiology, the resurgence of primary percutaneous intervention in acute coronary syndromes, the use of percutaneous devices in patients previously considered inoperable, and the withdrawal of aprotinin. Against this landscape, this invaluable resource has been fully updated. New chapters are dedicated to right heart valves, pulmonary vascular disease, cardiac tumours and cardiac trauma. All other chapters have been updated according to the latest international guidelines. Written and edited by an international author team with a wealth of expertise in all aspects of the perioperative care of cardiac patients, topics are presented in an easy to digest and a readily accessible manner. Core Topics in Cardiac Anaesthesia, Second Edition is essential reading for residents and fellows in anaesthesia and cardiac surgery and clinical perfusionists. |
| excitation-contraction coupling diagram: Disorders of Voluntary Muscle George Karpati, David Hilton-Jones, Robert C. Griggs, 2001-07-12 Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle. |
| excitation-contraction coupling diagram: Fundamentals of Anaesthesia Colin Pinnock, Ted Lin, Robert Jones, Tim Smith, 2002-12 The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout. |
| excitation-contraction coupling diagram: Smooth Muscle Spontaneous Activity Hikaru Hashitani, Richard J. Lang, 2019-06-10 This book presents the commonality and heterogeneity of the mechanisms underlying smooth muscle spontaneous activity in various smooth muscle organs and in addition discusses their malfunctions in disease and their potential as novel therapeutic targets. To facilitate understanding, the volume is divided into five parts and covers 16 organs: airways, gastrointestinal tract (phasic muscle, tonic muscle), renal pelvis, ureter, urinary bladder, urethra, corporal tissue, prostate, uterus, oviducts, seminal vesicle, artery, vein, microvasculature, and lymphatic vessels. This structure will help readers to comprehend the most up-to-date information on the similarities and differences in the contractile mechanisms driving various smooth muscles as well as their potential manipulations in particular visceral organ pathologies. The vast advancements in gene, electrical recording, and imaging technologies in this field are also discussed, with review of past achievements and consideration of likely future developments. This book will be of worldwide interest to clinicians, students, and researchers alike. |
| excitation-contraction coupling diagram: Calcium Signaling Md. Shahidul Islam, 2019-10-23 This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. |
| excitation-contraction coupling diagram: Microscopy of the Heart Lars Kaestner, Peter Lipp, 2018-12-07 This book provides in depths information on different microscopy approaches and supplies the reader with methods how to untangle highly complex processes involved in physiological and pathophysiological cardiac signaling. Microscopy approaches have established themselves as the quasi gold standard that enables us to appreciate the underlying mechanisms of physiological and pathophysiological cardiac signaling. This book presents the most important microscopy techniques from the level of individual molecule e.g. Förster-Resonance Energy Transfer (FRET), up to cellular and tissue imaging, e.g. electron microscopy (TEM) or light sheet microscopy. The book is intended for graduate students and postdocs in cardiovascular research, imaging and cell biology, pre-clinical and clinical researchers in cardiovascular sciences as well as decision makers of the pharmaceutical industry. |
| excitation-contraction coupling diagram: Basic Physiology for Anaesthetists David Chambers, Christopher Huang, Gareth Matthews, 2019-07-25 Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource. |
| excitation-contraction coupling diagram: Electrodiagnosis in Diseases of Nerve and Muscle Jun Kimura, 2013-10 Intended for clinicians who perform electrodiagnostic procedures as an extension of their clinical examination, and for neurologists and physiatrists who are interested in neuromuscular disorders and noninvasive electrodiagnostic methods, particularly those practicing electromyography (EMG) this book provides a comprehensive review of most peripheral nerve and muscle diseases, including specific techniques and locations for performing each test. |
| excitation-contraction coupling diagram: Heart of the Matter Cesare Terracciano, Samuel Guymer, 2019-11-01 This textbook introduces readers to the scientific basics of cardiovascular medicine and biology. It covers not only developmental but also cellular and molecular aspects of normally functioning vasculature and the heart; importantly, it also addresses the mechanisms leading to and involved in specific cardiovascular diseases. Though the main emphasis is on novel therapies and potential therapeutic targets, specific controversial topics like cardiac remodeling and regenerative capacities are also addressed. All chapters were written by lecturers from the Imperial College London, in collaboration with their students from the College’s BSc Programme in Medical Sciences with Cardiovascular Science. Bridging the gap between clinics and basic biology, the book offers a valuable guide for medical students, and for Master and PhD students in Cardiovascular Biomedicine. |
| excitation-contraction coupling diagram: Excitation-Contraction Coupling and Cardiac Contractile Force D. M. Bers, 2001-08-31 Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). |
| excitation-contraction coupling diagram: Physics, Pharmacology and Physiology for Anaesthetists Matthew E. Cross, Emma V. E. Plunkett, 2014-03-06 A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams. |
| excitation-contraction coupling diagram: Molecular Biology of the Cell , 2002 |
| excitation-contraction coupling diagram: Neuromuscular Performance during Lifespan: Assessment Methods and Exercise Interventions Oliver Faude, Lars Donath, 2020-03-12 |
| excitation-contraction coupling diagram: Smooth Muscle Excitation T. B. Bolton, T. Tomita, 1996 This book is a compendium of the latest electrophysiological research on smooth muscles from an international collection of authors. It includes recent discoveries in calcium stores and their relationship to contraction and to electrical changes in the membrane. A major section of the book concentrates on calcium release mechanisms in the cell, their control, and the consequences of calcium release in the cell for membrane events. Smooth Muscle Excitation also covers the effects of chemicals released from adjacent cells. Key Features * State-of-the-art volume that represents a synopsis of all work currently being undertaken in this area throughout the world * Content covers both basic and clinical research * Provides a range of drug development studies * Presents contributions from many internationally recognized smooth muscle physiologists |
| excitation-contraction coupling diagram: Biology for AP ® Courses Julianne Zedalis, John Eggebrecht, 2017-10-16 Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences. |
| excitation-contraction coupling diagram: Musculoskeletal Disorders and the Workplace Institute of Medicine, National Research Council, Commission on Behavioral and Social Sciences and Education, Panel on Musculoskeletal Disorders and the Workplace, 2001-05-24 Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials. |
| excitation-contraction coupling diagram: Calcium Entry Channels in Non-Excitable Cells Juliusz Ashot Kozak, James W. Putney, Jr., 2017-07-14 Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche. |
| excitation-contraction coupling diagram: Structure and Function of Calcium Release Channels Irina Serysheva, 2010-09-22 This volume of Current Topics in Membranes focuses on Membrane Protein Crystallization, beginning with a review of past successes and general trends, then further discussing challenges of mebranes protein crystallization, cell free production of membrane proteins and novel lipids for membrane protein crystallization. This publication also includes tools to enchance membrane protein crystallization, technique advancements, and crystallization strategies used for photosystem I and its complexes, establishing Membrane Protein Crystallization as a needed, practical reference for researchers. |
| excitation-contraction coupling diagram: Discovering the Brain National Academy of Sciences, Institute of Medicine, Sandra Ackerman, 1992-01-01 The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the Decade of the Brain by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a field guide to the brainâ€an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€and how a gut feeling actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the Decade of the Brain, with a look at medical imaging techniquesâ€what various technologies can and cannot tell usâ€and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€and many scientists as wellâ€with a helpful guide to understanding the many discoveries that are sure to be announced throughout the Decade of the Brain. |
| excitation-contraction coupling diagram: Muscle Atrophy Junjie Xiao, 2018-11-02 The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology. |
| excitation-contraction coupling diagram: Muscles and Their Neural Control Graham Hoyle, 1983 Neurologie, Muskel, Muskelphysiologie. |
| excitation-contraction coupling diagram: Cell Physiology Source Book Nicholas Sperelakis, 2012-12-02 This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death. - Completely revised and updated - includes 8 new chapters on such topics as membrane structure, intracellular chloride regulation, transport, sensory receptors, pressure, and olfactory/taste receptors - Includes broad coverage of both animal and plant cells - Appendixes review basics of the propagation of action potentials, electricity, and cable properties - Authored by leading experts in the field - Clear, concise, comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics |
| excitation-contraction coupling diagram: Ion Channels in Health and Sickness Fatima Shad Kaneez, 2018-10-10 Ion channels are proteins that make pores in the membranes of excitable cells present both in the brain and the body. These cells are not only responsible for converting chemical and mechanical stimuli into the electrical signals but are also liable for monitoring vital functions. All our activities, from the blinking of our eyes to the beating of our heart and all our senses from smell to sight, touch, taste and hearing are regulated by the ion channels. This book will take us on an expedition describing the role of ion channels in congenital and acquired diseases and the challenges and limitations scientist are facing in the development of drugs targeting these membrane proteins. |
| excitation-contraction coupling diagram: Pediatric Critical Care Study Guide Steven E. Lucking, Frank A. Maffei, Robert F. Tamburro, Neal J. Thomas, 2012-04-10 This is the first comprehensive study guide covering all aspects of pediatric critical care medicine. It fills a void that exists in learning resources currently available to pediatric critical care practitioners. The major textbooks are excellent references, but do not allow concise reading on specific topics and are not intended to act as both text and study guide. There are also several handbooks available, but these are usually written for general pediatric residents and lack the advanced physiology and pathophysiology required for the higher level pediatric critical care practitioner |
| excitation-contraction coupling diagram: Botulinum Neurotoxins Andreas Rummel, Thomas Binz, 2015-01-29 The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application. |
| excitation-contraction coupling diagram: Foundations of Anesthesia Hugh C. Hemmings, Philip M. Hopkins, 2006-01-01 Accompanying CD-ROM ... allows you to download figures into PowerPoint for electronic presentations. -- p. [4] of cover. |
| excitation-contraction coupling diagram: Mechanisms of Vascular Disease Robert Fitridge, M. M. Thompson, 2011 New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes. |
| excitation-contraction coupling diagram: Applied Engineering Principles Manual - Training Manual (NAVSEA) Naval Sea Systems Command, 2019-07-15 Chapter 1 ELECTRICAL REVIEW 1.1 Fundamentals Of Electricity 1.2 Alternating Current Theory 1.3 Three-Phase Systems And Transformers 1.4 Generators 1.5 Motors 1.6 Motor Controllers 1.7 Electrical Safety 1.8 Storage Batteries 1.9 Electrical Measuring Instruments Chapter 2 ELECTRONICS REVIEW 2.1 Solid State Devices 2.2 Magnetic Amplifiers 2.3 Thermocouples 2.4 Resistance Thermometry 2.5 Nuclear Radiation Detectors 2.6 Nuclear Instrumentation Circuits 2.7 Differential Transformers 2.8 D-C Power Supplies 2.9 Digital Integrated Circuit Devices 2.10 Microprocessor-Based Computer Systems Chapter 3 REACTOR THEORY REVIEW 3.1 Basics 3.2 Stability Of The Nucleus 3.3 Reactions 3.4 Fission 3.5 Nuclear Reaction Cross Sections 3.6 Neutron Slowing Down 3.7 Thermal Equilibrium 3.8 Neutron Density, Flux, Reaction Rates, And Power 3.9 Slowing Down, Diffusion, And Migration Lengths 3.10 Neutron Life Cycle And The Six-Factor Formula 3.11 Buckling, Leakage, And Flux Shapes 3.12 Multiplication Factor 3.13 Temperature Coefficient... |
| excitation-contraction coupling diagram: Organellar Ion Channels and Transporters Barbara E. Ehrlich, David E. Clapham, 1996 |
Excitation | electron transitions, energy levels & spectroscopy ...
Excitation, in physics, the addition of a discrete amount of energy (called excitation energy) to a system—such as an atomic nucleus, an atom, or a molecule—that results in its alteration, …
Exciton - Wikipedia
An exciton is a bound state of an electron and an electron hole which are attracted to each other by the electrostatic Coulomb force resulting from their opposite charges.
EXCITATION | definition in the Cambridge English Dictionary
EXCITATION meaning: 1. the process of making something, for example a particle or a cell, more active: 2. the process…. Learn more.
EXCITATION definition and meaning | Collins English Dictionary
Excitation is the act of making something vibrate. If the ship's vibration is caused by the propeller, the excitation may be reduced by changing the propeller. The simplest form of excitation is to …
What is an excitation in physics? - Physics Network
Dec 17, 2024 · excitation, in physics, the addition of a discrete amount of energy (called excitation energy) to a system—such as an atomic nucleus, an atom, or a molecule—that results in its …
Excitation - (College Physics I – Introduction) - Fiveable
Excitation is the process of raising an atom or nucleus from a lower energy state to a higher energy state, typically through the absorption of energy in the form of light, heat, or other forms of …
What does Excitation mean? - Definitions.net
Excitation generally refers to the state of being energized, stimulated, activated or aroused. This term is often used in various fields like physics, chemistry, physiology, psychology, and …
EXCITATION Definition & Meaning - Merriam-Webster
The meaning of EXCITATION is excitement; especially : the disturbed or altered condition resulting from stimulation of an individual, organ, tissue, or cell.
EXCITATION Definition & Meaning - Dictionary.com
Excitation definition: the act of exciting.. See examples of EXCITATION used in a sentence.
Excitation and Ionisation - PhysicsA-Level Revision - Revision …
Excitation is the result of energy being given to an electron moving it to a higher energy level. It will still orbit the nucleus, unless the electron energy level is greater than the ionisation energy level …
Excitation | electron transitions, energy levels & spectroscopy ...
Excitation, in physics, the addition of a discrete amount of energy (called excitation energy) to a system—such as an atomic nucleus, an atom, or a molecule—that results in its alteration, …
Exciton - Wikipedia
An exciton is a bound state of an electron and an electron hole which are attracted to each other by the electrostatic Coulomb force resulting from their opposite charges.
EXCITATION | definition in the Cambridge English Dictionary
EXCITATION meaning: 1. the process of making something, for example a particle or a cell, more active: 2. the process…. Learn more.
EXCITATION definition and meaning | Collins English Dictionary
Excitation is the act of making something vibrate. If the ship's vibration is caused by the propeller, the excitation may be reduced by changing the propeller. The simplest form of excitation is to …
What is an excitation in physics? - Physics Network
Dec 17, 2024 · excitation, in physics, the addition of a discrete amount of energy (called excitation energy) to a system—such as an atomic nucleus, an atom, or a molecule—that results in its …
Excitation - (College Physics I – Introduction) - Fiveable
Excitation is the process of raising an atom or nucleus from a lower energy state to a higher energy state, typically through the absorption of energy in the form of light, heat, or other forms of …
What does Excitation mean? - Definitions.net
Excitation generally refers to the state of being energized, stimulated, activated or aroused. This term is often used in various fields like physics, chemistry, physiology, psychology, and …
EXCITATION Definition & Meaning - Merriam-Webster
The meaning of EXCITATION is excitement; especially : the disturbed or altered condition resulting from stimulation of an individual, organ, tissue, or cell.
EXCITATION Definition & Meaning - Dictionary.com
Excitation definition: the act of exciting.. See examples of EXCITATION used in a sentence.
Excitation and Ionisation - PhysicsA-Level Revision - Revision …
Excitation is the result of energy being given to an electron moving it to a higher energy level. It will still orbit the nucleus, unless the electron energy level is greater than the ionisation energy level …
