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| exosome therapy for neuropathy: Stem Cell-Derived Exosome Therapy of Microbial Diseases: From Bench to Bed Amin Tamadon, Reza Shirazi, Nader Tanideh, 2022-03-16 |
| exosome therapy for neuropathy: Diabetes and the Nervous System Douglas W. Zochodne, Rayaz A. Malik, 2014-12-26 This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson's disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system. |
| exosome therapy for neuropathy: Differentiation and Regulation of Bone Marrow Mesenchymal Stromal Cells Xiao Chen, Chao Xie, Ce Dou, Zhenhong Ni, 2022-08-11 |
| exosome therapy for neuropathy: Thrive Beyond Diabetes in 2024 Azhar ul Haque Sario, 2024-10-02 Tired of diabetes dictating your life? Ready to break free and truly thrive? Imagine waking up each day with boundless energy, feeling in control of your health, not held back by the limits of diabetes. That's exactly what Thrive Beyond Diabetes is all about. This isn't your average diabetes book. It's your personal roadmap to a life where diabetes doesn't just take a backseat, it practically disappears in your rearview mirror. We're talking about living longer, feeling healthier, and rediscovering the joy in everyday moments. Whether you're newly diagnosed or a seasoned veteran, Thrive Beyond Diabetes in 2024 is your key to unlocking a life you never thought possible. It's packed with real-world advice, inspiring stories, and the latest science to guide you on your journey. This isn't about just managing diabetes – it's about thriving beyond it. Get ready to rewrite your story, one delicious meal, one invigorating workout, and one well-rested night at a time. Your adventure to a life filled with health, vitality, and endless possibilities starts now. |
| exosome therapy for neuropathy: The Application of AI and Other Advanced Technology in Studying Eye Diseases and Visual Development Haotian Lin, Yihai Cao, Wenbin Wei, Wei Chi, 2023-01-31 |
| exosome therapy for neuropathy: Applications of Stem Cells and Derived Exosomes in Neurodegenerative Disorders Sadaf Jahan, |
| exosome therapy for neuropathy: Exosomes as Therapeutic Systems Robert Steven Conlan, Deyarina Gonzalez, Bruna Corradetti, Ines Mendes Pinto, 2021-10-01 |
| exosome therapy for neuropathy: Inflammatory immune disease: Molecular mechanisms, translational approaches and therapeutics volume II Tao Xu, Qingzhong Xiao, Jian Gao, Cheng Chen, 2023-03-17 |
| exosome therapy for neuropathy: Focus on Chronic Pain: Neuropathological Mechanism, Clinical Diagnosis and Treatment Boris Krylov, Tao Song, Ma Ke, Yan Lu, Dong Huang, 2024-01-15 Pain is an unpleasant sensory and emotional experience and the most frequent causes for patients to seek medical care. Persistent chronic pain affects millions of people worldwide, causing low quality of health and emotional status, as well as posing a significant social and economic burden. Chronic pain is the long-standing pain that are classified as different types, including chronic primary pain and secondary pain types caused by various diseases. The complexity of cause and symptom in chronic pain is associated with changes in different levels of nervous system, from molecular interaction, synaptic connection, cellular response, and neural circuits. The development of new treatments to manage chronic pain shall base on the better standing of the neuropathological mechanism underlying the symptom, the exploration on the methods of a better diagnosis, and the communication of clinical application standards and results. |
| exosome therapy for neuropathy: Translational Nanomedicine Robert A. Meyers, 2020-03-16 The largest high-level encyclopedia on molecular medicine is now publishing a topical volume on Nanomedicine. The long awaited volume gives a comprehensive overview on nanomaterials in drug delivery, imaging and as therapeutics. |
| exosome therapy for neuropathy: Stem Cell Therapy for Diabetes Shimon Efrat, 2009-12-01 Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes. |
| exosome therapy for neuropathy: Spinal Cord Injury (SCI) Repair Strategies Giuseppe Perale, Filippo Rossi, 2019-10-30 Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair. - Covers current and future repair strategies for spinal cord injury repair - Focuses on key research trends, clinics, biology and engineering - Provides fundamentals on regenerative engineering and tissue engineering |
| exosome therapy for neuropathy: Chemotherapy-Induced Neuropathic Pain Robert B. Raffa, Richard Langford, Jr. Pergolizzi, Frank Porreca, Ronald J. Tallarida, 2012-07-24 There have been tremendous recent advances in the pharmacotherapy, dose regimens, and combinations used to treat cancer and for the treatment or prevention of the spread of disease. As a direct result of these advances, there are an increasing number of cancer survivors, although research dealing with chemotherapy-induced pain is still in its early |
| exosome therapy for neuropathy: Cognition and Cancer Christina A. Meyers, James R. Perry, 2012-12-13 This book is a unique resource on the influence cancer and cancer treatments have on cognition. The majority of cancer patients on active treatment experience cognitive impairments often referred to as 'chemobrain' or 'chemofog'. In addition, patients with primary or metastatic tumors of the brain often experience direct neurologic symptoms. This book helps health care professionals working with cancer patients who experience cognitive changes and provides practical information to help improve care by reviewing and describing brain-behavior relationships; research-based evidence on cognitive changes that occur with various cancers and cancer treatments; assessment techniques, including neurocognitive assessment and neuroimaging techniques; and intervention strategies for affected patients. In short, it will explain how to identify, assess and treat these conditions. |
| exosome therapy for neuropathy: Index Medicus , 2004 Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings. |
| exosome therapy for neuropathy: Orthobiologics Giuseppe Filardo, Bert R. Mandelbaum, George F. Muschler, Scott A. Rodeo, Norimasa Nakamura, 2021-12-02 This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts. |
| exosome therapy for neuropathy: Exosomal RNA Debalina Bhattacharya, Mainak Mukhopadhyay, Kursad Turksen, 2024-03-29 Exosomal RNA: Role in Human Diseases and Therapy provides an in-depth study of exosomes and their RNA in the context of a variety of diseases. The book explores the diagnostic and therapeutic potential of exosomal RNA as biomarkers across a range of different conditions, including cancer, type 2 diabetes, cardiovascular and renal disease, as well as bacterial infections and tissue repair. The link between exosomal RNA expression and neurodegenerative disease is also explored. The book goes on to share the significance of exosomal RNA in preserving cellular function, with special attention given to their role in the autophagy process. This book gives an overview of the isolation, characterization, and potential applications of exosomal RNA, providing researchers with an understanding of how they can be manipulated and utilized for the treatment of various diseases and conditions. This is an ideal reference for researchers in the field of molecular biology, cell biology, and related fields, as well as those involved in the development of therapeutics and personalized medicine. - Provides an introduction into exosomal RNA and their potential as predictive and diagnostic biomarkers for various conditions - Considers exosomal RNA in a variety of human disorders, including metabolic diseases, inflammatory diseases, and cancer - Discusses the role of exosomal RNA in preserving the cellular environment and its role in the autophagy process |
| exosome therapy for neuropathy: New Insights Into Schizophrenia-Related Neural and Behavioral Phenotypes Yuh-Man Sun, Ji Chen, 2023-06-01 |
| exosome therapy for neuropathy: Improving Outcomes in Diabetic Foot Care - A Worldwide Perspective Richard Paisey, José Luis Lázaro Martínez, Joanne Paton, Frances Game , Honda Hsu, 2024-11-11 Enhanced population longevity, decrease in physical activity and the obesity pandemic have resulted in an increase in incidence of type 2 diabetes in all WHO health care areas. The prevalence of the condition has been further increased by an increase in life expectancy of those living with both type 1 and type 2 diabetes as a result of lifestyle and therapeutic interventions. Microvascular complications of type 1 and type 2 diabetes mellitus are related to duration of the condition and include neuropathy in 20% of cases in all cultures. Diabetic peripheral neuropathy in combination with propensity to distal peripheral vascular disease, poor healing, infection and foot deformities often result in foot ulceration and a uniquely high minor and major amputation risk. The risk for foot ulceration is modified by ethnicity (foot flexibility) and life style (footwear and culture of walking bare-foot). Once a deep diabetic foot ulcer has developed the epidermis, dermis, tendon insertions and bone architecture will never return to normal . The lack of resilience in the scar tissue formed and foot deformity after a deep ulcer will confer a high risk of re-ulceration-in fact previous foot ulceration is by far the highest risk factor for occurrence of a foot wound in persons living with diabetes. |
| exosome therapy for neuropathy: Mesenchymal Stem Cell Therapy Lucas G. Chase, Mohan C Vemuri, 2012-12-12 Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field. |
| exosome therapy for neuropathy: Research Advances in Gestational Diabetes Mellitus, Neonatal Diabetes Mellitus, and Metabolic Disorders Ihtisham Bukhari, Furhan Iqbal, Rick Francis Thorne, 2022-09-05 |
| exosome therapy for neuropathy: Blood-Derived Products for Tissue Repair/Regeneration Isabel Andia, Nicola Maffulli, 2019-12-18 This Special Issue on “Blood-Derived Products for Tissue Repair and Regeneration” reveals the evolution and diversity of platelet rich plasma (PRP) technologies, which includes experimental research on novel formulations, the creation of combination therapies, and the exploration of potential modifiers of PRPs, as well as efficacy of PRP therapies in clinical veterinary and human applications. Scientist and clinicians are now starting to develop different treatments based on their reinterpretation of the traditional roles of platelets and plasma, and the current Issue has provided a forum for sharing research and ways of understanding the associated medicinal benefits from different points of view. The research interest in this area has covered different medical disciplines, such as ophthalmology, dentistry, orthopedics, and sports medicine. |
| exosome therapy for neuropathy: Neurodegeneration Anthony Schapira, Zbigniew K. Wszolek, Ted M. Dawson, Nicholas Wood, 2017-04-24 This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson’s Disease, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors |
| exosome therapy for neuropathy: Biomaterials for Cell-Based Therapy Liyuan Zhang, Huanan Wang, Xuetao Shi, 2022-02-08 |
| exosome therapy for neuropathy: Mitochondrial Dysfunction Lawrence H. Lash, Dean P. Jones, 2013-10-22 Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable. |
| exosome therapy for neuropathy: Nucleic Acid Drugs Akira Murakami, 2012-07-04 New Antisense Strategies: Chemical Synthesis of RNA Oligomers, by Junichi Yano und Gerald E. Smyth Development and Modification of Decoy Oligodeoxynucleotides for Clinical Application, by Mariana Kiomy Osako, Hironori Nakagami und Ryuichi Morishita Modulation of Endosomal Toll-Like Receptor-Mediated Immune Responses by Synthetic Oligonucleotides, by Ekambar R. Kandimalla und Sudhir Agrawal Delivery of Nucleic Acid Drugs, by Yan Lee und Kazunori Kataoka Aptamer: Biology to Applications, by Yoshikazu Nakamura Development and Clinical Applications of Nucleic Acid Therapeutics, by Veenu Aishwarya, Anna Kalota und Alan M. Gewirtz |
| exosome therapy for neuropathy: Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives Neil H. Riordan, 2017-06-20 Stem cells are the repair cells of your body. When there aren't enough of them, or they aren't working properly, chronic diseases can manifest and persist. From industry leaders, sport stars, and Hollywood icons to thousands of everyday, ordinary people, stem cell therapy has helped when standard medicine failed. Many of them had lost hope. These are their stories. Neil H Riordan, author of MSC: Clinical Evidence Leading Medicine's Next Frontier, the definitive textbook on clinical stem cell therapy, brings you an easy-to-read book about how and why stem cells work, and why they're the wave of the future. |
| exosome therapy for neuropathy: Immune Surveillance Richard T. Smith, 2012-12-02 Immune Surveillance deals with the issues regarding tumor immunology and surveillance, in which the central theme is all about the life span of the mammalian host that is depleted by the environment with mutagenic agents and solutions. The book is divided into six chapters. It includes discussions on the organization and modulation of cell membrane receptors, as well as the origin and expression of membrane antigens. It also covers the topics on the triggering mechanisms for and effector mechanisms activated by the cellular recognition. These topics analyze and evaluate alternatives for the recognition and destruction mechanisms in the knowledge of cell cooperation and requirements for immune recognition. A chapter provides discourse on a solution for the paradox of thriving tumors based on the demonstrable in vitro host immunity. Another discusses the generation of antibody diversity and the theory of self-tolerance. The last chapter explains the evaluation of the evidence for immune surveillance. This reference will be invaluable to those who specialize in immunology. |
| exosome therapy for neuropathy: Pain Models Hermann O. Handwerker, Lars Arendt-Nielson, 2015-06-01 The neurobiology and mechanisms discovered in animals often do not translate to patients with a chronic pain condition. To help researchers and clinicians develop and use models that can help translate data from animals into humans, this book presents experimental animal models, with a focus on how they may translate into humans human experimental pain models, including details about pain induction and assessment human surrogate pain models clinical applications of pain models models that may link mechanisms of pain and pruritus Pain Models contains 29 chapters by internationally recognized experts. It is a comprehensive survey of pain models at different levels, and commentaries by clinicians directly address clinical perspectives. This unique book is unprecedented in its content. It's a quick reminder of the hard work needed to investigate the complex issue of pain perception. With the advent of increasingly sensitive noninvasive investigational tools, the authors want readers to know that basic research is still needed to help develop new drugs. This book will enrich anyone who wishes to know all that goes into conducting pain research with a lab-based pain model. |
| exosome therapy for neuropathy: Peroxisomal Disorders and Regulation of Genes Frank Roels, Myriam Baes, R. Delanghe, 2003-12-31 In most peroxisomal disorders the nervous system is severely affected which explains the clinical and community burden they represent. This is the first book to focus not only on the mutations causing these inherited illnesses, but also on mechanisms that regulate, suppress or enhance expression of genes and their products (enzymes). Indeed since the success and completion of the Human Genome Project all genes (coding DNA sequences) are known. However, of many, their function, and the role of the gene product has not been determined. An example is X-linked adrenoleukodystrophy, the most frequent peroxisomal disorder. Children are born healthy, but in more than 1 out of 3, demyelination of the brain starts unpredictably and they die in a vegetative state. The gene mutated in most families has been known for 10 years; but the true role of the encoded protein, ALDp, is still speculative; and within the same family, very severe and asymptomatic clinical histories co-exist, unexplained by the mutation. |
| exosome therapy for neuropathy: Metabolic Factors in Erectile Dysfunction Xianghu Meng, Ke Rao, Jun Chen, 2024-01-03 |
| exosome therapy for neuropathy: Fabry Disease Deborah Elstein, Gheona Altarescu, Michael Beck, 2010-08-02 Fabry disease is an X-linked inborn error of metabolism wherein deficiency of a lysosomal enzyme results in systemic deposition of glycosphingolipids. Storage deposition, and hence pathological disease, occurs preferentially in renal glomerular and tubular epithelial cells, myocardial cells, heart valve fibrocytes, neurons of dorsal root ganglia, and in endothelial smooth muscle cells of blood vessels. Thus, Fabry disease is a multi-system disorder, albeit with considerable phenotypic heterogeneity in onset and in severity; however, it is progressive, exhibits extensive morbidity, and is life-threatening. Within the past two decades, there has been a radical change in the natural course Fabry disease by virtue of the availability of specific enzyme replacement therapy. Moreover, there has been a concerted effort to better understand the underlying pathology and equally to identify patients prior to the onset of irreversible end-organ damage. It is to be hoped that the future for patients with Fabry disease can be viewed with greater, albeit guarded, optimism. This state-of-the-art textbook attempts to bridge the span of pre-clinical studies, clinical finding, and management options in a readable but comprehensive manner for the medical practitioner as well as the interested non-medical reader. |
| exosome therapy for neuropathy: Proteomic Profiling Anton Posch, 2021-02-04 This detailed new edition presents the latest developments of the main pillars of protein analysis, namely sample preparation, separation, and characterization. Core areas in this volume are protocols for the analysis of post-translational modifications and protein interaction partners, followed by sophisticated procedures to enrich for extracellular vesicles and organelles, along with several types of protein immuno-assays complemented by various methods for the characterization of antibodies and host-cell protein analysis. Last but not least, a few standard sample preparation protocols and recent advances concerning immuno-chemical detection of proteins are included as well. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Proteomic Profiling: Methods and Protocols, Second Edition serves as an ideal reference for students of biochemistry, biomedicine, biology, and genomics and will be an invaluable source for the experienced, practicing scientist as well. |
| exosome therapy for neuropathy: Extracellular Vesicles Qian Wang, |
| exosome therapy for neuropathy: Macromolecular Protein Complexes III: Structure and Function J. Robin Harris, Jon Marles-Wright, 2020-11-30 This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein–protein interactions in the human adenovirus capsid, to mention but a few. The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. |
| exosome therapy for neuropathy: Dental Stem Cells: Regenerative Potential Barbara Zavan, Eriberto Bressan, 2016-07-25 This book focuses on the basic aspects of dental stem cells (DSCs) as well as their clinical applications in tissue engineering and regenerative medicine. It opens with a discussion of classification, protocols, and properties of DSCs and proceeds to explore DSCs within the contexts of cryopreservation; epigenetics; pulp, periodontal, tooth, bone, and corneal stroma regeneration; neuronal properties, mesenchymal stem cells and biomaterials; and as sources of hepatocytes for liver disease treatment. The fifteen expertly authored chapters comprehensively examine possible applications of DSCs and provide invaluable insights into mechanisms of growth and differentiation. Dental Stem Cells: Regenerative Potential draws from a wealth of international perspectives and is an essential addition to the developing literature on dental stem cells. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is indispensable for biomedical researchers interested in bioengineering, dentistry, tissue engineering, regenerative medicine, cell biology and oncology. |
| exosome therapy for neuropathy: Role of stem cell derivatives in inflammatory diseases Cuiping Zhang, Haihong Li, Zhe Li, Jiang Huai Wang, Yong Ming Yao, 2023-10-03 |
| exosome therapy for neuropathy: Stem Cell Drugs - A New Generation of Biopharmaceuticals Phuc Van Pham, 2018-10-25 This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications. Each chapter is contributed by a pre-eminent scientist in the field. An introductory section presents current stem cell drugs and stem cell-based products and a discussion of production, quality control, mechanisms, and efficacy. Following sections include discussions on stem cell-derived microvesicles based products, and derived exosomes based products. Stem Cell Drugs - A New Generation of Biopharmaceuticals and the other books in the Stem Cells in Clinical Applications series are invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering. This groundbreaking volume is also essential reading for those researching or studying drug development or pharmaceutical science. |
| exosome therapy for neuropathy: Novel Therapies for Combating Bone Diseases through Advances in Bone Remodeling Chao Liang, Jiake Xu, Changjun Li, 2022-01-17 |
| exosome therapy for neuropathy: Biomarkers in Toxicology Ramesh C Gupta, 2019-02-13 Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. - Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers - Includes completely revised chapters, along with additional chapters on the newest developments in the field - Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure - Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more |
Exosome (vesicle) - Wikipedia
Exosomes, ranging in size from 30 to 150 nanometers, [1] are membrane-bound extracellular vesicles (EVs) that are produced in the endosomal compartment of most eukaryotic cells. …
Q&A: What are exosomes, exactly? | BMC Biology | Full Text
Jun 13, 2016 · Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and explored as …
The biology, function, and biomedical applications of exosomes
Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They are mediators of near and long-distance intercellular …
Exosomes: a review of biologic function, diagnostic and targeted ...
Jul 11, 2024 · In this review, we briefly discuss the composition of exocomes and exosome isolation. We also review the clinical applications of exosomes in cancer biology as well as …
Exosomes - PubMed
Jun 20, 2019 · Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected proteins, lipids, …
Exosome | Definition, Size, & Function | Britannica
Exosome, nano-sized vesicle secreted from cells that contains any of various biomolecules, such as proteins or nucleic acids. Intercellular communication by exosomes plays a critical role in …
Exosomes: Biogenesis, Composition, and Roles in Health and …
Apr 29, 2025 · Understanding exosome biogenesis, composition, and functions could unlock new therapeutic avenues. This article delves into the intricate processes behind exosome …
Exosomes: Biological function, Clinical Potential & Utility (2025)
Apr 9, 2025 · Exosomes are small, membrane-bound vesicles produced by cells, typically between 30 and 100 nanometers in diameter. They originate from the endosomal …
Exosomes: composition, biogenesis and function - Nature
Aug 1, 2002 · Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Interest in exosomes has intensified after their recent description in …
An Introduction of Exosomes
Jun 9, 2025 · The process of exosome generation takes several hours to days and is closely dependent on the cell types, the physiological state of the cells, and the influences of external …
Exosome (vesicle) - Wikipedia
Exosomes, ranging in size from 30 to 150 nanometers, [1] are membrane-bound extracellular vesicles (EVs) that are produced in the endosomal compartment of most eukaryotic …
Q&A: What are exosomes, exactly? | BMC Biology | Full …
Jun 13, 2016 · Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and …
The biology, function, and biomedical applications of ex…
Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They are mediators of near and long-distance intercellular …
Exosomes: a review of biologic function, diagnostic and targe…
Jul 11, 2024 · In this review, we briefly discuss the composition of exocomes and exosome isolation. We also review the clinical applications of exosomes in cancer biology as well as strategies …
Exosomes - PubMed
Jun 20, 2019 · Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected proteins, …
