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exosome therapy for anti aging: Mesenchymal Stem Cell Derived Exosomes Yaoliang Tang, Buddhadeb Dawn, 2015-09-02 Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. - Introduces the MSC-exosome mediated cell-cell communication - Covers the major functional benefits in current MSC-derived exosome studies - Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies |
exosome therapy for anti aging: Cosmetic Dermatology Zoe Diana Draelos, 2015-10-14 Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again. |
exosome therapy for anti aging: Timeless Beauty: Anti-Aging for a Healthy Life Shu Chen Hou, Unlock the Secret to Ageless Beauty! Are you ready to turn back the hands of time and unveil a more youthful, vibrant you? Discover the keys to Timeless Beauty: Anti-Aging for a Healthy Life, your definitive guide to a healthier, more youthful existence! 🌟 Reclaim Your Youth: Delve into the science behind aging and uncover the secrets to slowing down the clock. From nutrition and fitness to stress management and advanced skincare, this book is your roadmap to lasting vitality. 💪 Empower Your Health: Learn how to create a holistic, anti-aging lifestyle that suits you. Harness the power of cutting-edge treatments, natural remedies, and the wisdom of centenarians from around the world. 🌿 Beauty That Lasts: Explore the latest skincare innovations and beauty routines that will leave your skin glowing and your confidence soaring. Discover the confidence that comes with a radiant, age-defying appearance. 🚀 Future-Proof Your Life: Stay ahead of the curve with insights into emerging anti-aging technologies and trends. Be at the forefront of a revolution in longevity and well-being. Your journey to timeless beauty starts now. With Timeless Beauty: Anti-Aging for a Healthy Life, you'll not only look your best but also feel your best. Join countless others who have unlocked the secrets to a healthier, more youthful life. Get your copy today and embrace the ageless beauty within you! |
exosome therapy for anti aging: Tissue Barriers in Disease, Injury and Regeneration Nikolai V. Gorbunov, 2021-06-19 Tissue Barriers in Disease, Injury and Regeneration focuses on the molecular and cellular fundamentals of homeostatic and defense responses of tissue barriers, covering the damaging impacts and exposure to pathogens and engineered nanomaterials. Sections emphasize the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells, along with reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and metabolic status. Other sections cover the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, vasculature of blood-tissue barriers, and more. - Includes special emphasis on the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells in the development of reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and in metabolic status - Examines the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, the vasculature of blood-tissue barriers, and mucosa and external epithelium |
exosome therapy for anti aging: Exosomes in Cardiovascular Diseases Junjie Xiao, Sanda Cretoiu, 2017-09-19 The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist. |
exosome therapy for anti aging: Anti-Aging Made Easy Eliza Hayton, 2024-01-23 In a world where the pursuit of longevity and youthful vitality is an ever-present desire, this comprehensive guide emerges as a beacon of knowledge and empowerment. This comprehensive guide is a roadmap to not only understanding the aging process but also mastering the art of slowing it down. Embark on a transformative journey through the pages of this book, where science meets practical wisdom to unveil the secrets of anti-aging. From lifestyle choices to cutting-edge research, this guide explores a myriad of strategies that can help you maintain your youthfulness and enhance your overall well-being. This is not just a manual; it's a companion for those who aspire to not only add years to their lives but life to their years. With actionable tips, evidence-based advice, and a holistic approach, this book empowers you to take control of your aging process. It's time to redefine aging, embrace vitality, and discover the keys to a longer, healthier, and more fulfilling life. Your journey to staying young longer begins here. |
exosome therapy for anti aging: Genomic and Precision Medicine Geoffrey S. Ginsburg, Huntington F Willard, John Strickler, Matthew Stuart McKinney, 2022-04-09 Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. - Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers - Includes succinct commentary and key learning points that will assist providers with their local needs for implementation of genomic and personalized medicine into practice - Presents an up-to-date overview on major opportunities for genomic and personalized medicine in practice - Covers case studies that highlight the practical use of genomics in the management of patients |
exosome therapy for anti aging: Regulation of Cancer Immune Checkpoints , 2020 This book systematically reviews the most important findings on cancer immune checkpoints, sharing essential insights into this rapidly evolving yet largely unexplored research topic. The past decade has seen major advances in cancer immune checkpoint therapy, which has demonstrated impressive clinical benefits. The family of checkpoints for mediating cancer immune evasion now includes CTLA-4, PD-1/PD-L1, CD27/CD70, FGL-1/LAG-3, Siglec-15, VISTA (PD-1L)/VSIG3, CD47/SIRPA, APOE/LILRB4, TIGIT, and many others. Despite these strides, most patients do not show lasting remission, and some cancers have been completely resistant to the therapy. The potentially lethal adverse effects of checkpoint blockade represent another major challenge, the mechanisms of which remain poorly understood. Compared to the cancer signaling pathways, such as p53 and Ras, mechanistic studies on immune checkpoint pathways are still in their infancy. To improve the responses to checkpoint blockade therapy and limit the adverse effects, it is essential to understand the molecular regulation of checkpoint molecules in both malignant and healthy cells/tissues. This book begins with an introduction to immune checkpoint therapy and its challenges, and subsequently describes the regulation of checkpoints at different levels. In closing, it discusses recent therapeutic developments based on mechanistic findings, and outlines goals for future translational studies. The book offers a valuable resource for researchers in the cancer immunotherapy field, helping to form a roadmap for checkpoint regulation and develop safer and more effective immunotherapies. |
exosome therapy for anti aging: Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications Wing-Fu Lai, 2020-10-19 This book presents a multidisciplinary assessment of the state of science in the use of systemic delivery technologies to deliver anti-aging therapeutics now under development. There is a gap between basic aging research and the development of intervention technologies. This major obstacle must be overcome before biogerontological interventions can be put into clinical practice. As biogerontology comes to understand aging as a systemic degenerative process, it is clear that there is a pressing need for technologies that enable cells and tissues in a fully developed adult body to be manipulated systemically to combat aging. The authors review advances in the chemistry and engineering of systemic delivery methods and analyze the strengths and limitations of each. The book is organized into six sections. The first offers an overview of the need for systemic delivery technologies alongside the development of anti-aging therapies and describes approaches that will be required for studying the properties and efficiency of carriers for systemic delivery. Sections II, III and IV describe recent advances in a range of strategies that may enable systemic delivery to help combat aging conditions ranging from cell senescence to decline in immune function and hormonal secretion. Section V discusses practical strategies to engineer and optimize the performance of delivery technologies for applications in systemic delivery, along with their working principles. The final section discusses technical and biological barriers that must be overcome as systemic delivery technologies move from research laboratory to clinical applications aimed at tackling aging and age-associated diseases. Benefiting scholars, students and a broader audience of interested readers, the book includes helpful glossary sections in each chapter, as well as sidebars that highlight important notes, and questions for future research. |
exosome therapy for anti aging: Non-Surgical Skin Tightening and Lifting Murad Alam, Jeffrey S. Dover, 2008-01-01 This new title presents up-to-the-minute guidance on the hottest non-surgical skin tightening and lifting techniques shaping today's practice. It focuses on procedural how-tos and offers step-by-step advice on proper techniques, pitfalls, and tricks of the trade. |
exosome therapy for anti aging: Tendon Regeneration Manuela E. Gomes, Rui L. Reis, Márcia T. Rodrigues, 2015-08-08 Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field. - Provides an overview of tendon biology, disease, and tissue engineering approaches - Presents modern, alternative approaches to developing functional tissue solutions discussed - Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine - Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices - Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field |
exosome therapy for anti aging: Cutaneous Wound Healing Vincent Falanga, 2001-08-23 Gene therapy, bioengineered skin, and other methods in advanced biology are revolutionizing the treatment of wounds. Written by experts in research and clinical practice, Cutaneous Wound Healing examines the current knowledge and emerging treatment methods. This volume explains the normal molecular and cellular functions that occur when a wound heals, as well as dysfunctional events, such as a chronic wound or an ulcer. Such dysfunctions signal an imbalance in the body, explained here along with possible treatments. The book's mini-atlas is an indispensable reference tool. Dermatologists, plastic surgeons, and general practitioners can benefit from this text. |
exosome therapy for anti aging: A Comprehensive Guide to Male Aesthetic and Reconstructive Plastic Surgery Seth R. Thaller, |
exosome therapy for anti aging: Frailty and Sarcopenia Yannis Dionyssiotis, 2017-08-30 Frailty is considered a multisystem impairment that makes an individual vulnerable to external or internal stressors. Sarcopenia, the age-dependent loss of muscle mass and function, is proposed as the biological substrate and the pathway whereby the consequences of physical frailty develop. These syndromes are associated with a negative impact in quality of life and can lead to the occurrence of disability, institutionalization, and even mortality. The book focuses upon all the related aspects of frailty and sarcopenia and the new advancements in the related treatments including complex issues and research. It includes high-quality chapters in all related aspects for the syndromes of sarcopenia and frailty, which adversely affect the function and overall effectiveness of the musculoskeletal system and interventions to promote rehabilitation. |
exosome therapy for anti aging: Translational Nanomedicine Robert A. Meyers, 2020-03-16 The largest high-level encyclopedia on molecular medicine is now publishing a topical volume on Nanomedicine. The long awaited volume gives a comprehensive overview on nanomaterials in drug delivery, imaging and as therapeutics. |
exosome therapy for anti aging: A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics Xiao-Dong Chen, 2018-08-31 A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. - Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy - Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials - Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward - Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies |
exosome therapy for anti aging: The Structure and Function of Skin William Montagna, 1972 |
exosome therapy for anti aging: Healthy Aging Eliza Hayton, 2024-01-23 This book contains 3 titles, which are the following: Anti-Aging Made Easy - Embark on a transformative journey through the pages of this book, where science meets practical wisdom to unveil the secrets of anti-aging. From lifestyle choices to cutting-edge research, this guide explores a myriad of strategies that can help you maintain your youthfulness and enhance your overall well-being. Elder Care - As our society ages, understanding the unique needs of seniors becomes crucial. Elder Care unfolds the layers of geriatric care management, offering insights into the physical, emotional, and social aspects of aging. From healthcare considerations to emotional support, financial planning to fostering a nurturing environment, this book equips its readers with the knowledge and tools necessary to navigate the challenges and celebrate the joys of elder care. Vitamins - In the fascinating world of health and well-being, embark on a journey with our book. As the title suggests, this comprehensive guide is a treasure trove of information on how vitamins play a pivotal role in slowing down the aging process, enhancing your skin's radiance, combating hair loss, and ultimately rejuvenating your entire being. Join us on a quest to unlock the secrets of these essential micronutrients, discover the science behind their remarkable effects, and empower yourself to embrace a vibrant and youthful life. Get ready to delve into the transformative power of vitamins, as we unravel the keys to not just looking, but feeling younger from the inside out. |
exosome therapy for anti aging: Mesenchymal Stem Cell Therapy Lucas G. Chase, Mohan C Vemuri, 2012-12-12 Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field. |
exosome therapy for anti aging: Aging Michael Fossel, 2024-02-29 Aging: How Aging Works, How We Reverse Aging, and Prospects for Curing Aging Diseases explains the process of aging beyond mere entropy, exposing it as a complicated and dynamic process that undercuts maintenance and permits age-related disease. With a deeper understanding of the aging process, intervention becomes both easy to understand and clinically feasible. With a solid academic approach, this proposed book builds upon the substantial work published over the past 20 years, citing the newest data, up-to-date models based upon that data, and the implications for improved clinical intervention, including recent developments in gene and cell therapy. Coverage of age-related diseases includes neurodegenerative, cardiovascular, bone and joint, immune system, renal, pulmonary, and skin aging. Future directions of the field focus on interventions, including a summary of previous attempts to intervene in aging and age-related disease, the status of current research, and proposed biotech interventions, as well as their potential obstacles, risks, and benefits. This is the perfect reference for scientists, clinicians, and researchers interested in the translational research opportunities such as drug discovery, pharmacogenetics, and experimental therapeutics, not only summarizing where the field stands, but giving a clear and cogent view of where clinical medicine is going in the next decade. - Provides a sophisticated, accurate, and clear explanation of aging - Gives a clear explanation of the fundamental role of cell aging in age-related disease - Offers a unified model for the role of epigenetic and telomere changes in cell aging - Outlines effective approaches to intervention in the fundamental aging process - Introduces upcoming interventions intended to both cure and prevent age-related diseases |
exosome therapy for anti aging: Intercellular Communication in Cancer Mustapha Kandouz, 2015-11-20 Cells are by nature compelled to live in groups. They develop dependence over signaling cues received from their microenvironment, in particular from other cells, whether of their own “kind” or of a different type. Therefore, communicating with these cells is a critical aspect of their behavior and fate, as they live and die normally or as they undergo disease-related pathological changes, with dramatic repercussions. In this book, we have asked expert researchers in the field of Intercellular Communication in Cancer to provide chapters on different aspects of interaction between neighboring cells, in the context of cancer diseases. We have specifically focused our efforts on membrane-to-membrane contact-based rather than growth factors-mediated modes of intercellular communications. The contributing authors provide an extensive overview of their respective area of specialization, with an in-depth discussion of the molecular mechanisms of cell-cell interactions, the impact on tumor progression and response to therapies, as well as the cancer diagnostic value of this scientific information. This book aims to introduce essential aspects of the normal and pathological cellular fate and homeostasis to both scientists and clinicians, and also to provide established researchers with an update on the novelties and future directions this expanding field is witnessing. |
exosome therapy for anti aging: Osteogenesis and Bone Regeneration Haisheng Yang, 2019 Osteogenesis is a core component of the skeletal system and depends on the well-coordinated proliferation and differentiation of osteogenic cells. Multiple signaling pathways and transcriptional factors tightly regulate the process of osteogenesis. Any abnormities in bone formation could cause severe disorders such as osteogenesis imperfecta and osteoporosis. Bone regeneration, a complex and well-orchestrated physiological process of osteogenesis, remains a medical challenge in the field of orthopedics and maxillofacial surgery. This book provides an overview of the current developments in osteogenesis and bone regeneration, including molecular and cellular mechanisms, physical therapies (low-level laser, distraction osteogenesis), biological therapies (mesenchymal stem cells, stem cell derived exosomes, inflammatory factor, Chinese medicine), as well as tissue engineering approaches promoting bone regeneration by targeting osteogenesis. |
exosome therapy for anti aging: Stem Cells Mariusz Z. Ratajczak, 2020-01-02 Since different types of stem cells for therapeutic applications have recently been proposed, this timely volume explores various sources of stem cells for tissue and organ regeneration and discusses their advantages and limitations. Also discussed are pros and cons for using embryonic stem cells, induced pluripotent stem cells, and adult stem cells isolated from postnatal tissues. Different types of adult stem cells for therapeutic applications are also reviewed, including hematopoietic stem cells, epidermal stem cells, endothelial progenitors, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells. This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented. This is an ideal book for students and researchers working in the stem cell research field. |
exosome therapy for anti aging: Human Mesenchymal Stem Cells Mitchell Khan, 2021 In Chapter 1, the COVID-19 pandemic and the damage mechanisms on the cellular level which can be ameliorated with the cellular therapies is thoroughly evaluated. Previous and ongoing stem cell clinical trial data from diseases with similar symptoms is gathered. All this accumulated data and current clinical trial results indicate that the cellular therapies could be the most effective treatment option for COVID-19 patients to ameliorate the damaged tissues and save lives. In Chapter 2, the authors examine activated mesenchymal stem cells for stroke repair. Stem Cell treatment has shown recovery in animal models of stroke, indicating an improved regenerative and repair potential. Though stem cells are still being used in clinical trials, there is no evidence that they enhance recovery in ischemic stroke patients. Nevertheless, the multipotent mesenchymal stem has widely been explored for stroke recovery. An'Activated MSC' as a therapeutic alternative to tackling ischemic stroke is proposed, thereby the activation of MSCs by cytokines, growth factors, hypoxia, pharmacological drugs, etc., could be a novel approach to improving stroke patients' responses to receiving MSCs. In Chapter 3, the potential benefits of in vitro culture of therapeutic stem cells in the presence of HB along with the ketogenic diet, whereby higher physiological concentrations of ketone bodies can be achieved in vivo, as an adjuvant to stem cell transplantation is assessed-- |
exosome therapy for anti aging: Stem Cell Banking Dusko Ilic, 2014-05-05 This book exemplifies experience across the globe in banking of cord blood, mesenchymal, embryonic and induced pluripotent stem cells for clinical use from the United States, Canada, the European Union, Switzerland and Japan to Iran, India and Serbia. The concerns are similar regardless of stem cell type or origin. Implementing core values and common standards depend often on specific circumstances of political and economic setting, which makes flexibility as important as systematic planning. Banking of stem cells is not just building a repository and storing samples. The planning, design, construction and maintenance involve multiple skilled professionals. Stem cell banks are points where technology and medicine converge with ethics, laws and regulations. If properly designed and organized, their utilization will have a broad impact not only on the scientific community and medical professionals but also on the general public. |
exosome therapy for anti aging: Skin Photoaging Rui Yin, Qiquan Chen, Michael R. Hamblin, 2014-04-01 This book focuses on skin photoaging, the premature aging of skin due to environmental effects such as exposure to UV (UVA, UVB) radiation from the sun. Slowing the aging process and rejuvenation have been one of the major goals of medicine and are in high |
exosome therapy for anti aging: Smart Materials for Tissue Engineering Qun Wang, 2016-12-13 In recent years there has been tremendous progress in the area of tissue engineering research. This book focusses on the fundamental principles underpinning these recent advances in the materials science developed for tissue engineering purposes. Smart materials for tissue engineering are produced by modifying the physicochemical and biological properties of the scaffolds with response to external stimuli to enhance the tissue regeneration. The functions of living cells can be regulated by smart materials which respond to changes in the surrounding microenvironment. This book comprehensively documents the recent advancements in smart materials for tissue engineering and will provide an essential text for those working in materials science and materials engineering, in academia and industry. |
exosome therapy for anti aging: Comorbidity in Rheumatic Diseases Yasser El Miedany, 2017-08-24 This book explores comorbidity in patients with rheumatic diseases and details both care and treatment options in standard clinical practice. Patients with rheumatic diseases are clinically complex, and the interplay of their disease activity with associated conditions may lead to increased morbidity and mortality. Recently there have been major advances in the management of rheumatic diseases, however, without addressing the potential comorbid conditions, including cardiovascular disease; pulmonary disease; and depression; outcomes remain poor. With its 19 chapters, covering the management of major rheumatic diseases (e.g. rheumatoid arthritis, systemic lupus erythematosus , and osteoarthritis), potential comorbidities and treatment recommendations, as well as possible interactions between conditions; this book addresses the gap between textbook medicine and day to day patients' care. Authors also discuss the new hot issue of the comorbidity index, comparing the standard tools to the recently developed indices and how they can assist the rheumatologists in determining disease burden, prognosis, and comorbidity probability. This book is an ideal clinical guide and reference that enables rheumatologists, internal medicine physicians, and residents to address the full clinical expression of these rheumatic diseases with views towards prevention or early management of comorbid conditions. |
exosome therapy for anti aging: Handbook of Stem Cell Therapy Khawaja Husnain Haider, 2022-11-07 The handbook comprehensively reviews the therapeutic potential of stem cells and stem cell secretome-based cell-free strategies in regenerative medicine. The chapters in section I and section II respectively discuss the diverse applications of mesenchymal stem cells and non- mesenchymal stem cells, including skeletal myoblasts, endothelial progenitor cells, adipose tissue-derived stem cells, induced pluripotent stem cells, and neuronal stem cells in myocardial repair, inflammatory bowel disease, cognitive deficits, wound healing, retinal disorders, and COVID-19. The subsequent chapters in section IIIprimarily focused on the fast-emerging cell-free therapy approach in regenerative medicine for tissue repair and regeneration. These chapters review the impact of stem cell-derived secretome on various biological processes such as angiogenesis, neurogenesis, tissue repair, immunomodulation, musculoskeletal pathologies, wound healing, anti-fibrotic, and anti-tumorigenesis for tissue maintenance and regeneration.Lastly, section IV summarizes miscellaneous aspects of cell-based therapy, includingthe treatment advantages, opportunities, and shortcomings in stem cell-based therapy, potentially helping to refine future studies and translate them from experimental to clinical studies. Moreover, this section also has chapters on cancer stem cells as novel targets in cancer therapeutics. This Major Reference Book (MRW) is a valuable resource for researchers involved in stem cell research to understand the multifaceted therapeutic applications of stem cells and their derivative secretome in regenerative medicine. |
exosome therapy for anti aging: Advanced Healthcare Materials Ashutosh Tiwari, 2014-05-19 Advanced materials are attracting strong interest in the fundamental as well as applied sciences and are being extensively explored for their potential usage in a range of healthcare technological and biological applications. Advanced Healthcare Nanomaterials summarises the current status of knowledge in the fields of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, up and coming bio-engineering devices. The book highlights the key features which enable engineers to design stimuli-responsive smart nanoparticles, novel biomaterials, nano/micro-devices for diagnosis, therapy (theranostics).The leading contributor researchers cover the following topics: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers The book is written for readers from diverse backgrounds across chemistry, physics, materials science and engineering, medical science, pharmacy, biotechnology, and biomedical engineering. It offers a comprehensive view of cutting-edge research on advanced materials for healthcare technology and applications. |
exosome therapy for anti aging: YŪGEN Magazine Skincare Anarchy, 2023-08-03 Skincare Anarchy, the beauty podcast that has taken the cosmetic industry by storm, with a collection of hundreds of full-length interviews spotlighting the brains behind the beauty, and is taking their features to the next level. This volume includes our 2023 Science of Skin winners, guides to the best skincare of the summer, & more! YŪGEN, a hybrid publication of beauty editorial, interview features, and a peer-reviewed medical journal, is a fully interactive, magazine-like e-pub with direct links to Spotify podcasts for all podcast episodes featured. Best of all, volume 2 is fully open access just like volume 1! “This is our testament to the brains behind the beauty” (Dr. Ekta). Sign up for first access via the Skincare Anarchy Email 📧 List (https://linktr.ee/Skincareanarchy (https://linktr.ee/Skincareanarchy))! Accepting PR pitches for future volumes, and to inquire about coming on our podcast Skincare Anarchy! Email: PR@skincareanarchypodcast.com |
exosome therapy for anti aging: From Taboo to Wellness: The Facts behind Menopause Peter Hollands, 2023-03-24 |
exosome therapy for anti aging: Regenerative Plastic Surgery Pietro Gentile (Plastic surgeon), 2020-11-24 Regenerating damaged organs and tissues, an act that once was considered magic, is currently entrusted to the surgeons who have allowed us to move from replacement and reconstructive plastic surgery to regenerative plastic surgery, through autologous and allogeneic cell-based therapies and growth factors. The enthusiasm for regenerative plastic surgery and for the treatment of some pathologies addressed by it, such as breast reconstruction, hemifacial atrophy, burns, scars, and aesthetic improvements such as breast and buttock augmentation, face rejuvenation and hair regrowth, has led the author, Professor Pietro Gentile, to rigorously investigate the possible new minimally invasive strategies based on adipose-derived stem cells, human follicle stem cells and growth factors contained in platelet-rich plasma. This book reports on the latest knowledge regarding the treatment of soft and bone tissue defects. Therefore, the goal of this text is to introduce and definitively establish this new and interesting field of plastic surgery, called regenerative plastic surgery-- |
exosome therapy for anti aging: MicroRNA Protocols Shao-Yao Ying, 2008-02-04 MicroRNA Protocols provides diverse, novel, and useful descriptions of miRNAs in several species, including plants, worms, flies, fish, chicks, mice, and humans. These include some useful adaptations and applications that could be relevant to the wider research community who are already familiar with the identification of miRNAs. This volume will stimulate the reader to explore diverse ways to understanding the mechanism in which miRNAs facilitate the molecular aspects of the biomedical research. |
exosome therapy for anti aging: Tumor Microenvironment Alexander Birbrair, 2020-02-10 Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on non-hematopoietic cells within the tumor microenvironment.Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include fibroblasts, adipocytes, mesenchymal stem cells, stellate cells, and more. Taken alongside its companion volumes, Tumor Microenvironment: Non-Hematopoietic Cells updates us on what we know about the different aspects of the tumor microenvironment as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists focused in the tumor microenvironment and how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment. All of the chapter authors are renowned international experts in the cancer biology field in specific subfields that will be the focus of their chapters. |
exosome therapy for anti aging: Microenvironmental stimuli-responsive nanomedicine for biomedical application Yong Hu, Jingwei Xie, Donglin Xia, 2023-05-31 |
exosome therapy for anti aging: Molecular Basis and Emerging Strategies for Anti-aging Interventions Syed Ibrahim Rizvi, Ufuk Çakatay, 2018-11-02 This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences. |
exosome therapy for anti aging: Extracellular vesicles in cardiovascular diseases Junjie Yang, Zhen-Ao Zhao, Zhongjian Cheng, Phuong-Uyen Dinh, Ke Huang, Zhenhua Li, 2023-05-26 |
exosome therapy for anti aging: The Variant Gene Julian Di Donato, 2024-01-25 We are at the tipping point of the ability to re-engineer humans, genetically editing out of our DNA the things we don't want and editing in the things we do. That world is a very different one from the one we living in right now. The way we can get there and what could happen when we do is explored in The Variant Gene. Starting with one man and one groundbreaking company, we are taken on a fast-paced journey of what his future may hold. The choices he makes and the risks he takes can save his life and thousands of others, while those same choices can make or lose billions for the biotech company that can not only cure him but extend his life for decades. |
exosome therapy for anti aging: Aulton's Pharmaceutics Michael E. Aulton, Kevin Taylor, 2013 Pharmaceutics is the art of pharmaceutical preparations. It encompasses design of drugs, their manufacture and the elimination of micro-organisms from the products. This book encompasses all of these areas.--Provided by publisher. |
Exosome (vesicle) - Wikipedia
Exosomes, ranging in size from 30 to 150 nanometers, [1] are membrane-bound extracellular vesicles (EVs) that are produced in the endosomal compartment of most eukaryotic cells. …
Q&A: What are exosomes, exactly? | BMC Biology | Full Text
Jun 13, 2016 · Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and explored as …
The biology, function, and biomedical applications of exosomes
Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They are mediators of near and long-distance intercellular …
Exosomes: a review of biologic function, diagnostic and targeted ...
Jul 11, 2024 · In this review, we briefly discuss the composition of exocomes and exosome isolation. We also review the clinical applications of exosomes in cancer biology as well as …
Exosomes - PubMed
Jun 20, 2019 · Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected proteins, lipids, …
Exosome | Definition, Size, & Function | Britannica
Exosome, nano-sized vesicle secreted from cells that contains any of various biomolecules, such as proteins or nucleic acids. Intercellular communication by exosomes plays a critical role in …
Exosomes: Biogenesis, Composition, and Roles in Health and Disease
Apr 29, 2025 · Understanding exosome biogenesis, composition, and functions could unlock new therapeutic avenues. This article delves into the intricate processes behind exosome …
Exosomes: Biological function, Clinical Potential & Utility (2025)
Apr 9, 2025 · Exosomes are small, membrane-bound vesicles produced by cells, typically between 30 and 100 nanometers in diameter. They originate from the endosomal …
Exosomes: composition, biogenesis and function - Nature
Aug 1, 2002 · Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Interest in exosomes has intensified after their recent description in …
An Introduction of Exosomes
Jun 9, 2025 · The process of exosome generation takes several hours to days and is closely dependent on the cell types, the physiological state of the cells, and the influences of external …
Exosome (vesicle) - Wikipedia
Exosomes, ranging in size from 30 to 150 nanometers, [1] are membrane-bound extracellular vesicles (EVs) that are produced in the endosomal compartment of most eukaryotic cells. …
Q&A: What are exosomes, exactly? | BMC Biology | Full Text
Jun 13, 2016 · Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and explored as …
The biology, function, and biomedical applications of exosomes
Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They are mediators of near and long-distance intercellular …
Exosomes: a review of biologic function, diagnostic and targeted ...
Jul 11, 2024 · In this review, we briefly discuss the composition of exocomes and exosome isolation. We also review the clinical applications of exosomes in cancer biology as well as …
Exosomes - PubMed
Jun 20, 2019 · Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected proteins, lipids, …
Exosome | Definition, Size, & Function | Britannica
Exosome, nano-sized vesicle secreted from cells that contains any of various biomolecules, such as proteins or nucleic acids. Intercellular communication by exosomes plays a critical role in …
Exosomes: Biogenesis, Composition, and Roles in Health and …
Apr 29, 2025 · Understanding exosome biogenesis, composition, and functions could unlock new therapeutic avenues. This article delves into the intricate processes behind exosome …
Exosomes: Biological function, Clinical Potential & Utility (2025)
Apr 9, 2025 · Exosomes are small, membrane-bound vesicles produced by cells, typically between 30 and 100 nanometers in diameter. They originate from the endosomal …
Exosomes: composition, biogenesis and function - Nature
Aug 1, 2002 · Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Interest in exosomes has intensified after their recent description in …
An Introduction of Exosomes
Jun 9, 2025 · The process of exosome generation takes several hours to days and is closely dependent on the cell types, the physiological state of the cells, and the influences of external …