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| family history of endometrial cancer: Recent Advances in Endometrial Cancer Sumita Mehta, Bindiya Gupta, 2020-07-23 This book discusses in detail the recent advances in the management of endometrial cancer, including the latest therapies and diagnostic methods. The book focuses on treatment-oriented topics such as the role of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in endometrial cancer, and also explores treatment options in advanced disease stages, including hormonal therapy and targeted therapy. Providing insights into the evidence-based management guidelines for endometrial cancer, this book is a valuable resource for students, trainees and practitioners in the field of gynecology and gyne-oncology. |
| family history of endometrial cancer: Rubin's Pathology David S. Strayer, Jeffrey E. Saffitz, Emanuel Rubin, 2019-09-09 With a simple approach to essential information, Rubin’s Pathology: Mechanisms of Human Disease establishes the foundation for medical training and practice and delivers the perfect balance of basic pathology and bedside perspective to confidently and efficiently equip students for clinical success. More accessible than ever, this eighth edition emphasizes the coverage students need most—disease mechanisms, integration of mechanisms into organ system pathology, and application of pathobiology to diagnostic medicine—in an approachable format with systems-based instruction techniques in mind. Comprehensively revised and updated content reflects the latest approaches to pathology from global leaders in the field and ensures a clinically relevant understanding of key pathology competencies. |
| family history of endometrial cancer: Practical Guide to Oral Exams in Obstetrics and Gynecology Görker Sel, 2019-11-13 This book, based on non-interactive question-and-answer format, offers an essential guide for medical students who need to prepare for oral exams or clinical visits. Starting from specific clinical situations the volume provides clear questions on the theory related to the cases. Each question is followed by correct answers that summarize the main information. Suggested reading are included to deepen the topics and enhance the readers knowledge. Accordingly, this practical guide will help students get ready for their oral exams, and help prepare young residents for their first clinical cases. |
| family history of endometrial cancer: Clinical Gynecology Eric J. Bieber, Joseph S. Sanfilippo, Ira R. Horowitz, Mahmood I. Shafi, 2015-04-23 Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings. |
| family history of endometrial cancer: Management of Endometrial Cancer Mansoor R. Mirza, 2019-08-26 This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence. |
| family history of endometrial cancer: Gynaecological Oncology for the MRCOG Mahmood Shafi, Helen Bolton, Ketankumar Gajjar, 2018-04-19 Extensive and up-to-date resource on the full range of gynaecological cancers; practically-focused and essential for the MRCOG examination. |
| family history of endometrial cancer: A Guide to Genetic Counseling Wendy R. Uhlmann, Jane L. Schuette, Beverly M. Yashar, 2011-09-20 The first book devoted exclusively to the principles and practice of genetic counseling—now in a new edition First published in 1998, A Guide to Genetic Counseling quickly became a bestselling and widely recognized text, used nationally and internationally in genetic counseling training programs. Now in its eagerly anticipated Second Edition, it provides a thoroughly revised and comprehensive overview of genetic counseling, focusing on the components, theoretical framework, and unique approach to patient care that are the basis of this profession. The book defines the core competencies and covers the genetic counseling process from case initiation to completion—in addition to addressing global professional issues—with an emphasis on describing fundamental principles and practices. Chapters are written by leaders in the field of genetic counseling and are organized to facilitate academic instruction and skill attainment. They provide the most up-to-date coverage of: The history and practice of genetic counseling Family history Interviewing Case preparation and management Psychosocial counseling Patient education Risk communication and decision-making Medical genetics evaluation Understanding genetic testing Medical documentation Multicultural counseling Ethical and legal issues Student supervision Genetic counseling research Professional development Genetics education and outreach Evolving roles and expanding opportunities Case examples A Guide to Genetic Counseling, Second Edition belongs on the syllabi of all medical and human genetics and genetic counseling training programs. It is an indispensable reference for both students and healthcare professionals working with patients who have or are at risk for genetic conditions. |
| family history of endometrial cancer: Genetics of Colorectal Cancer John D. Potter, Noralane M. Lindor, 2008-12-08 Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology. |
| family history of endometrial cancer: Daughter of Family G Ami McKay, 2019-09-24 Weaving together family history, genetic discovery, and scenes from her life, Ami McKay tells the compelling, true-science story of her own family's unsettling legacy of hereditary cancer while exploring the challenges that come from carrying the mutation that not only killed many people you loved, but might also kill you. The story of Ami McKay's connection to a genetic disorder called Lynch syndrome begins over seventy years before she was born and long before scientists discovered DNA. In 1895 her great-great aunt, Pauline Gross, a seamstress in Ann Arbor, Michigan, confided to a pathology professor at the local university that she expected to die young, like so many others in her family. Rather than dismiss her fears, the pathologist chose to enlist Pauline in the careful tracking of those in her family tree who had died of cancer. Pauline's premonition proved true--she died at 46--but because of her efforts, her family (who the pathologist dubbed 'Family G') would become the longest and most detailed cancer genealogy ever studied in the world. A century after Pauline's confession, researchers would identify the genetic mutation responsible for the family's woes. Now known as Lynch syndrome, the genetic condition predisposes its carriers to several types of cancer, including colorectal, endometrial, ovarian and pancreatic. In 2001, as a young mother with two sons and a keen interest in survival, Ami McKay was among the first to be tested for Lynch syndrome. She had a feeling she'd test positive: her mother's side of the family was riddled with early deaths and her own mother was being treated for the disease. When the test proved her fears true, she began living in an unsettling state between wellness and cancer, and she's been there ever since. Intimate, candid, and probing, her genetic memoir tells a fascinating story, teasing out the many ways to live with the hand you are dealt. |
| family history of endometrial cancer: Molecular Genetics of Endometrial Carcinoma Lora Hedrick Ellenson, 2016-12-01 This comprehensive text provides a much-needed review of a disease that is currently garnering the interest of molecular biologists, translational scientists, and clinicians. The volume includes emerging developments in the molecular genetics of endometrial carcinoma. In addition to covering the basic genetics of endometrial carcinoma, chapters also cover a wide range of signaling pathways implicated in endometrial carcinoma. A section of the book includes a number of genetically engineered mouse models, which contribute to understanding the role of various genetic alterations in the development and progression of endometrial carcinoma. These models also provide preclinical models for developing effective targeted therapeutic approaches. Endometrial carcinoma is the most common malignancy of the female genital tract in the United States and the number of cases continues to increase around the world. This book is a meant to serve as a resource for a wide range of scientists, from molecular geneticists to signal transduction biologists, as well as to both clinicians and scientists interested in developing targeted therapeutic approaches for women with endometrial carcinoma. |
| family history of endometrial cancer: Take Control of Your Cancer Risk John Whyte, MD, MPH, 2021-10-05 Something everyone has the power to do is reduce your cancer risk, and this book will show you just how easy it is to do it. Each year, over a million people in the United States alone hear the words no one ever wants to hear: You have cancer. But what if there was a way for fewer people to hear these words? One of the biggest myths regarding cancer is that it’s mostly genetic - meaning that you have no control over whether you get it. While genetics do have an impact, the truth is that your lifestyle and environment play the major role. Physician and Chief Medical Offer of WebMD John Whyte, MD, MPH, shares straightforward information and equips you with strategies to help you on a journey to better health. In Take Control of Your Cancer Risk, Dr. Whyte provides helpful tips including: assessing your cancer risk knowing which screenings you need, and when learning the role food, exercise, and sleep play understanding the relationship between stress and cancer Take Control of Your Cancer Risk is filled with practical advice that empowers you to really take control of our health. |
| family history of endometrial cancer: Ovarian and Fallopian Tube Cancer John Kavanagh, 1998-11-25 This book derived from the section of the same name from Cancer in Women, represents a concise overview of the current approaches to the diagnosis and management of ovarian cancer. Therapeutic chapters cover surgery and reconstruction, radiotherpay and adjuvant therapy. |
| family history of endometrial cancer: Concise Handbook of Familial Cancer Susceptibility Syndromes , 2008 |
| family history of endometrial cancer: Clinical Gynecologic Oncology E-Book Philip J. DiSaia, William T. Creasman, Robert S Mannel, D. Scott McMeekin, David G Mutch, 2017-02-04 The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers – a must-have reference for improving outcomes and providing effective care. A who’s who list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference. Contains useful appendices covering staging, screening, nutritional therapy, toxicity criteria, blood component therapy, and radiation therapy. Covers hot topics such as multi-panel genetic testing, target therapies, sentinel node concept in endometrial cancer and vulvar cancer, and robotic surgery. Updates include new quick-reference features such as key point boxes with bulleted lists, highlighted key text, enhanced chapter outlines, and a brand-new design throughout. Includes up-to-date references and algorithms, making this text a comprehensive resource for clinical practice, personal study, and exam review. Helps you take advantage of the latest advances in early detection and improved treatment options for gynecologic cancers, especially uterine and cervical cancers. |
| family history of endometrial cancer: AJCC Cancer Staging Manual Frederick L, Greene, David L. Page, Irvin D. Fleming, April G. Fritz, Charles M. Balch, Daniel G. Haller, Monica Morrow, 2013-11-21 The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms. |
| family history of endometrial cancer: A Cancer in the Family Theodora Ross, MD, PhD, Siddhartha Mukherjee, 2016-02-02 A Kirkus Best Book of 2016 Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States, and it’s estimated that about 1.3 million of these cases are hereditary. Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work. Using her own family’s story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers readers to face their genetic heritage without fear and to make decisions that will keep them and their families healthy. |
| family history of endometrial cancer: Cancer and Aging M. Extermann, 2013-01-18 Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners. |
| family history of endometrial cancer: Diagnosis and Management of Ovarian Disorders Albert Altchek, Liane Deligdisch, Nathan Kase, 2003-09-04 This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine |
| family history of endometrial cancer: Principles and Practice of Gynecologic Oncology William J. Hoskins, Carlos A. Perez, Robert Crabill Young, 2000 he thoroughly updated Third Edition of this acclaimed reference incorporates the latest advances in the multidisciplinary therapy of gynecologic cancer. The book provides comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies. Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist. New chapters in this edition cover laparoscopic surgery and national strategies for gynecologic cancer. More than 30 percent of the chapters have been completely rewritten. This edition also includes new full-color illustrations |
| family history of endometrial cancer: Gynaecological Oncology Mahmood I. Shafi, Helena M. Earl, Li Tee Tan, 2009-12-03 Providing a thorough and up-to-date overview of the full range of gynaecological cancers, Gynaecological Oncology is a concise introduction, particularly useful for trainees working towards postgraduate examinations. The first section includes introductory chapters on epidemiology, screening and prevention, imaging, pathology, surgery, radiation therapy, chemotherapy, and palliation. The second part of the book covers the gynaecological cancer types in turn; each chapter following a similar format looking at clinical issues, staging, and principles of management. Where appropriate, flow-charts and diagrams are used to help the reader assimilate complex information. A chapter is devoted to decision-making, addressing those issues clinicians and women face when deciding on optimal management in given clinical scenarios. The book is practically based and is enhanced by highlighting learning points, management algorithms and clinical images. This is an invaluable resource for all doctors and allied health professionals dealing with women with gynaecological cancers. |
| family history of endometrial cancer: The Uterus Henry J. Norris, Arthur Tremain Hertig, Murray R. Abell, 1973 |
| family history of endometrial cancer: Gynecologic Cancer Patricia J. Eifel, David M. Gershenson, John J. Kavanagh, Elvio G. Silva, 2005-12-21 Gynecologic cancer includes cancer of the female lower genital tract: vagina, vulva, cervix, endometrium, uterus, and ovaries. Gynecologic Cancer is the fourth volume in the M.D. Anderson Cancer Care Series, featuring the current standard approach to gynecologic cancer care from the experts at M.D. Anderson Cancer Center. Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include primary prevention and early detection, preinvasive diseases of female lower genital tract, pathology and imaging of gynecologica malignancies, treatment of vaginal, cervical, endometrial, uterine cancers. Discussions also address fertility-sparing options for treatment of women with gynecologica cancers as well as sexuality in women with gyn malignancies. Each of the 20 chapters ends with an up-to-date list of suggested readings, as well as key practice points highlighting the most principles and practices of each chapter for at-a-glance reference. More than 80 illustrations complement the text. This thorough, practical volume is the essential clinical guide for the oncologists, surgeons, and all physicians involved in the care of patients with gynecologic cancer. |
| family history of endometrial cancer: Oncofertility Teresa Woodruff, Laurie Zoloth, Lisa Campo-Engelstein, Sarah Rodriguez, 2012-11-06 Oncofertility has emerged as a way to address potential lost or impaired fertility in cancer patients and survivors, with active biomedical research that is developing new ways to help these individuals preserve their ability to have biological children. In order to move beyond oncofertility as a science and medical technology and begin to address the ethical, legal, and social ramifications of this emerging field, we must give voice to scholars from the humanities and social sciences to engage in a multidisciplinary discussion. This book brings together a pool of experts from a variety of fields, including communication, economics, ethics, history, law, religion, and sociology, to examine the complex issues raised by recent developments in oncofertility and to offer advice from national and international perspectives as we create new technology. Given the inherent interdisciplinary nature of oncofertility, this book is not only valuable, but also necessary to cultivate a deep understanding of new issues with the eventual aim of offering proposals for addressing them. Indeed, this book will be useful for people not only within the humanities and social sciences disciplines but also for those who are confronted with cancer and the possibility of impaired fertility and the medical practitioners within oncology and reproductive medicine who are at the front lines of this emerging field. |
| family history of endometrial cancer: Hereditary Colorectal Cancer Miguel A. Rodriguez-Bigas, Raul Cutait, Patrick M. Lynch, Ian Tomlinson, Hans F.A. Vasen, 2010-09-10 Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease. |
| family history of endometrial cancer: Breast Cancer Kelly K. Hunt, Geoffrey L. Robb, Eric A. Strom, Naoto T. Ueno, 2013-06-05 I am honored to write the Foreword for this first volume of the M. D. Anderson Cancer Care series, because I believe the book represents a milestone not only for M. D. Anderson but also for cancer specialists everywhere. All of us, whether we work in academic medical institu tions, medical school hospitals, community hospitals, oncology clinics, or solo practice, have seen remarkable changes in our practice over the recent decades. We know that breast cancer patients live longer, feel better, and look better than ever before, and they face this dreaded disease with more optimism than ever before. Each of us deserves to be proud of this progress. Though I am now primarily a laboratory scientist and admin istrator, I am proud of my own work on factors that control the growth of tumor cells, most prominently through regulation of EGF receptors and HER-2/neu, and the promise that work holds for women who have breast cancer. The authors represented in this volume have made important contri butions to breast cancer care. Likewise, every reader of this book has and will continue to make critical contributions to the health of women with breast cancer. I would like to express the hope here that each of us takes the opportunity to step outside our subspecialties-surgeon, internist, radiation oncologist, pathologist, radiologist, laboratory scientist-and learn how we can better integrate our work with that of other specialists. |
| family history of endometrial cancer: Ovarian Cancers National Academies of Sciences, Engineering, and Medicine, Institute of Medicine, Board on Health Care Services, Committee on the State of the Science in Ovarian Cancer Research, 2016-04-25 In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease-several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades is likely due to several factors, including the lack of research being performed by specific disease subtype, lack of definitive knowledge of the cell of origin and disease progression, and incomplete understanding of genetic and non-genetic risk factors. Ovarian Cancers examines the state of the science in ovarian cancer research, identifies key gaps in the evidence base and the challenges to addressing those gaps, considers opportunities for advancing ovarian cancer research, and examines avenues for translation and dissemination of new findings and communication of new information to patients and others. This study makes recommendations for public- and private-sector efforts that could facilitate progress in reducing the incidence of morbidity and mortality from ovarian cancers. |
| family history of endometrial cancer: Female Genital Tumours: Who Classification of Tumours W. H. O. Classification WHO Classification of Tumours Editorial Board, Who Classification of Tumours Editorial, 2020-09-30 ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Female Genital Tumours is the fourth volume in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. What's new in this edition? The 5th edition, guided by the WHO Classification of Tumours Editorial Board, will establish a single coherent cancer classification presented across a collection of individual volumes organized on the basis of anatomical site (digestive system, breast, soft tissue and bone, etc.) and structured in a systematic manner, with each tumour type listed within a taxonomic classification: site, category, family (class), type, and subtype. In each volume, the entities are now listed from benign to malignant and are described under an updated set of headings, including histopathology, diagnostic molecular pathology, staging, and easy-to-read essential and desirable diagnostic criteria. Who should read this book? - Pathologists - Oncologists - Cancer researchers - Surgeons - Epidemiologists - Cancer registrars This volume - Prepared by 191 authors and editors - Contributors from around the world - More than 850 high-quality images - More than 3100 references |
| family history of endometrial cancer: Diagnostic Gynecologic and Obstetric Pathology E-Book Christopher P. Crum, Kenneth R. Lee, Marisa R. Nucci, Scott R. Granter, Brooke E. Howitt, Mana M. Parast, Theonia Boyd, William A Peters III, 2017-10-13 Comprehensive and practice-oriented, the fully updated 3rd Edition of this easy-to-use text covers the full range of obstetric and gynecologic pathology, including information on treatment and patient management. Written largely by the pathology and clinical faculty at Harvard's Brigham and Women's Hospital, it covers the most up-to-date information available in the field, including molecular genetics and diagnostics. Drs. Christopher P. Crum and Marisa R. Nucci are joined by new editors Scott R. Granter, Brooke E. Howitt, Mana M. Parast, and Theonia K. Boyd, to provide complete, beautifully illustrated coverage of both neoplastic and non-neoplastic disorders of the female genital system, ideal for improving pathological diagnosis. - Provides distinct diagnostic/differential diagnostic criteria for any potential obstetric/gynecologic specimen encountered in practice. - Features more than 2,250 full-color images, key points at the end of each chapter, and an appendix with commonly used ICD-10 codes - Covers topics not often found in gynecologic pathology textbooks, such as vulvodynia, and diseases of the anus. - Approaches topics from a practice-oriented point of view, beginning with clinical presentation and progressing through histopathology, differential diagnosis, and treatment for each disorder. - Emphasizes new practice issues and their biologic basis including approaches to vulvar, cervical and endometrial precursors as well as the underpinnings of cervical, endometrial and ovarian cancer. - A comprehensive look at mesenchymal neoplasia, including not only lower genital tract and uterus but also the retroperitoneum. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. |
| family history of endometrial cancer: Pulmonary Metastasis Leonard Weiss, Harvey A. Gilbert, 1978 |
| family history of endometrial cancer: Surgery for Ovarian Cancer Robert E. Bristow, Beth Y. Karlan, Dennis S. Chi, 2019-02-21 Updated and expanded, the third edition of Surgery for Ovarian Cancer focuses on essential techniques for the effective management of ovarian cancer. It reflects the most contemporary science and surgical applications for the management of patients with ovarian cancer and related peritoneal surface malignancies. This new edition takes a step-by-step approach and includes new intraoperative photographs and videos illustrating surgical procedures. It is principally devoted to the technical aspects of cytoreductive surgery, with chapters divided according to anatomic region. The chapters cover relevant anatomical considerations, surgical challenges specific to each region, and operative approaches and techniques favored by the authors. The list of contributing authors has been expanded from the previous edition and includes international and world-renowned experts from the fields of gynecologic oncology and surgical oncology. The topics of minimally invasive surgery, secondary cytoreduction, palliative surgery, and postoperative care are also covered in detail. New to the third edition are chapters on preoperative risk stratification, regional therapeutics and peritonectomy procedures, and quality assurance relating to ovarian cancer surgery. This comprehensive text is essential reading for all practitioners working with patients with ovarian cancers. |
| family history of endometrial cancer: Current Concepts in Endometrial Cancer Ranu Patni, 2017-03-15 This book comprehensively covers endometrial carcinoma, a type of gynecological cancer that is often overlooked but of great interest. Although the incidence of the disease is rapidly increasing, both per se and as part of familial cancer syndromes, there is a great deal of controversy regarding its diagnosis, evaluation and management. This book underlines the significance of endometrial carcinoma, highlights key prevention measures, charts its evaluation, and addresses the stage-by-stage management of this malignancy, with particular attention to the role of minimally invasive surgery. Further, it includes a chapter on future perspectives including robotics, targeted therapies and other developments in the offing. divOverall, the book provides a comprehensive guide to endometrial cancer, which if approached properly, can have an excellent prognosis, thus saving many lives and/or achieving substantially improved quality of life.> |
| family history of endometrial cancer: The Human Endometrium Carlo Bulletti, Erlio Gurpide, Carlo Flamigni, 1994 The structural, biochemical and clinical events related to menstruation, implantation, parturition, endometriosis, abnormal uterine bleeding and endometrial cancer are discussed in this comprehensive volume on the biological functions of the endometrium. New topics, such as the biochemical and molecular mechanisms regulating maternal embryonic interaction, are explored, and gynecologic endoscopy and therapeutic tools are discussed. The proceedings of the first conference is also available from the Academy, as volume 622 of The Annals of The New York Academy of Science. |
| family history of endometrial cancer: Principles of Gender-Specific Medicine Marianne Legato J, 2009-10-29 The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men as well conditions that predominantly occur in women. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases. The Second Edition of Principles of Gender-Specific Medicine focuses on the essentials of gender-specific medicine and the current study of sex and gender differences in human physiology and pathophysiology. New section editors, new chapter authors, and new chapters have been added to reflect the most up-to-date clinical research and practice. - Offers insight into how the gender-specific risks of one organ system's disease affects the health of other organ systems - Outlines the sex-specific differences of normal anatomy and physiology - Illustrates the gender-specific features and quantifies gender and sex as risk factors across all major diseases - Qualifies and analyzes the results of new drug therapies designed with gender-specific differences in mind: ex, hormone therapy in men and women for the prevention and treatment of cardiovascular disease - All chapters progress translationally from the basic science to the clinical applications of gender-specific therapies, drugs, or treatments - Sections on drug metabolism, aging, and meta-analysis of data incorporated into all disease-specific chapters |
| family history of endometrial cancer: Cancer Evolution Charles Swanton, 2017 Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer. |
| family history of endometrial cancer: DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology Vincent T. DeVita Jr., Theodore S. Lawrence, Steven A. Rosenberg, 2015-01-07 DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues |
| family history of endometrial cancer: The Walnut Creek Contraceptive Drug Study Savitri Ramcharan, 1974 |
| family history of endometrial cancer: Inherited Gastrointestinal Cancers: Identification, Management and the Role of Genetic Evaluation and Testing, An Issue of Gastrointestinal Endoscopy Clinics, E-Book Fay Kastrinos, 2021-11-26 This issue of Gastrointestinal Endoscopy Clinics provides a multidisciplinary approach to the evaluation and care of individuals with inherited gastrointestinal cancer conditions. With the many recent advances made in genomic medicine and the potential impact on medical management, the articles in this issue disseminate new knowledge on the identification and management of individuals and families with a genetic susceptibility to the development of gastrointestinal cancers, including the genetic basis and cancer risks associated with inherited cancer syndromes and integrated familial cancer risk assessment; genetic testing approaches; and incorporating genetic risk counseling into routine medical care. The goal is to improve detection of GI cancer syndromes, understand related cancer risks, and optimize strategies for the prevention and early detection of cancers to minimize morbidity and mortality. Integrating genetic assessment into gastrointestinal cancer care is highly relevant across the cancer care spectrum and gastroenterologists will come away with the most current evidence to enhance and improve their clinical practice. - Provides in-depth, clinical reviews on Inherited GI Cancers: Identification, Management and the Role of Genetic Evaluation and Testing, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 11 relevant, practice-oriented topics including Defining High-Risk Individuals for Pancreatic Cancer and the Role of Genetic Testing; Endoscopic Management and Surgical Consideration for FAP-Related Polyposis; Genetic Syndromes Associated with Gastric Cancer; Screening and Surgical Considerations in Hereditary Diffuse Gastric Cancer; and more. |
| family history of endometrial cancer: DeVita, Hellman, and Rosenberg's Cancer Ramaswamy Govindan, Vincent T. DeVita, 2009 Based on DeVita, Lawrence, and Rosenberg's Cancer: Principles & Practice of Oncology, Eighth Edition, this comprehensive question-and-answer review book covers the entire specialty of oncology and provides thorough preparation for oncology boards. The book contains hundreds of multiple-choice and case-based questions covering the principles of surgical oncology, radiation oncology, medical oncology, and hematology/oncology and the biology, diagnosis, staging, and multimodality treatment of cancers at every anatomic site. Included are state-of-the-art chapters on molecular techniques, targeted therapies, and current approaches to cancer prevention. Questions are followed by answers and detailed explanations. A companion Website will offer an interactive question bank for individual self-testing. |
| family history of endometrial cancer: Prevention and Early Detection of Colorectal Cancer Graeme P. Young, Paul Rozen, Bernard Levin, 1996 This is an overview of the issues involved in prevention and early detection of colorectal cancer providing up-to-date, practical advice for clinicians. Possible management strategies for those at risk are provided, taking into account the biological principles of colorectal cancer development, epidemiological data and emerging genetic information, as well as social and environmental factors. |
| family history of endometrial cancer: Endometrial Cancer: From Biological to Clinical Approaches Massimo Nabissi, Frederic Amant, Paola Gehrig, 2019-09-26 In developed countries, cancer of the endometrium (EC) is the most common cancer of the female reproductive organs, affecting mainly postmenopausal women. The highest incidence of EC is in Northern America and Europe, but its incidence is growing around the world. Several factors influence the risk of developing EC, including: impaired hormone levels, obesity, physical activity, family history, and having been diagnosed with breast or ovarian cancer in the past. For EC, a standard screening test does not exist. It is often diagnosed at stage I/II due to frequent vaginal bleeding, while invasive EC (stage III/IV) is mainly diagnosed in its advanced stage. Despite the different clinical improvements when EC is progressed to the advanced/metastatic stage, the patients still have poor prognoses and unsatisfactory outcomes with conventional chemotherapy. The need for precision drugs is underscored by the limited number of options these patients have. So, the introduction of new techniques and the discovery of new biological characteristics, such as identification of transcriptome, proteome and metabolomics profiles, and new potential diagnostic/prognostic biomarkers are fundamental to improve our knowledges on EC. The scope of this Research Topic is to welcome articles and reviews from clinicians and scientists around the world in order to give an updated vision of the recent clinical insights, technical advances, and cellular and molecular targets related to endometrial cancer. Dedicated to Mr. Dario Conti, which supported endometrial cancer research. |
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