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| focal therapy prostate cancer nhs: Salvage Therapy for Prostate Cancer Sanchia S. Goonewardene, Raj Persad, Karen Ventii, David Albala, Declan Cahill, 2020-11-23 This book comprehensively covers application of salvage therapy in reccurrent prostate cancer. Chapters focus on specific issues associated with a range of surgical and oncological management techniques and strategies including hormone therapy, lymphnode dissection, robotic prostatectomy and salvage reirradiation after locoregional failure. Learning objectives, and definitions of keywords are provided to aid the reader develop a thorough understanding of the topic and reinforce the key points covered in each chapter. Salvage Therapy for Prostate Cancer provides a detailed practically applicable guide on how salvage therapy can be utilised in the treatment of prostate cancer. It represents a valuable resource for trainee and practicing urologists, oncologists, and specialist nurses. |
| focal therapy prostate cancer nhs: Clinical Naturopathic Medicine Leah Hechtman, 2012 Clinical Naturopathic Medicine is a foundation clinical text integrating the holistic traditional principles of naturopathic philosophy with the scientific rigour of evidence-based medicine (EBM) to support contemporary practices and principles. The text addresses all systems of the body and their related common conditions, with clear, accessible directions outlining how a practitioner can understand health from a naturopathic perspective and apply naturopathic medicines to treat patients individually. These treatments include herbal medicine, nutritional medicine and lifestyle recommendations. All chapters are structured by system and then by condition, so readers are easily able to navigate the content by chapter and heading structure. The content is designed for naturopathic practitioners and students (both undergraduate and postgraduate levels) and for medical and allied health professionals with an interest in integrative naturopathic medicine. detailed coverage of naturopathic treatments provides readers with a solid understanding of the major therapeutic modalities used within naturopathic medicine each system is reviewed from both naturopathic and mainstream medical perspectives to correlate the variations and synergies of treatment only clinically efficacious and evidence-based treatments have been included information is rigorously researched (over 7500 references) from both traditional texts and recent research papers the content skilfully bridges traditional practice and EBM to support confident practitioners within the current health care system |
| focal therapy prostate cancer nhs: Blandy's Urology Omar M. Aboumarzouk, 2019-05-06 Die 3. Auflage von Blandy?s Urology ist auf dem besten Weg, ein Klassiker zu werden. Die neueste Auflage eines der populärsten Fachbücher der Urologie vereint erfolgreich alles Wissenswerte zur allgemeinen Urologie und Chirurgie in der Urologie für die Zielgruppe der Urologen und Chirurgen. Hauptmerkmal ist die einzigartige Art und Weise von Blandy, urologische Erkrankungen und deren Management zu beschreiben: - Klare, direkte und unkomplizierte Beschreibungen von Krankheiten und Störungen mit Hunderten klinischer Fotos. - Eine Fülle exzellenter Schaubilder zu chirurgischen Eingriffen, die die besten Operationstechniken verdeutlichen. - Legt den Nachdruck auf die häufigsten Erkrankungen in der klinischen Praxis. - Jedes Thema ist einem anatomischen Bereich zugeordnet. Ein Fachbuch, das wegen seines direkten Zugangs zu dem Fachgebiet vor allem von Urologen und angehenden Chirurgen geschätzt wird. Eignet sich auch für die Prüfungsvorbereitung und als Auffrischung |
| focal therapy prostate cancer nhs: Stereotactic Body Radiation Therapy Simon S. Lo, Bin S. Teh, Jiade J. Lu, Tracey E. Schefter, 2012-08-28 Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists. |
| focal therapy prostate cancer nhs: Focal Therapy in Prostate Cancer Hashim Uddin Ahmed, Manit Arya, Peter R. Carroll, Mark Emberton, 2011-12-27 This book comprehensively reviews the potential of focal therapy and discusses why the changing face of prostate cancer warrants a change in the way we treat men with the disease. It deals with the mechanisms by which disease can be localized within the gland and then the different technologies used for focal ablation. Bringing together eminent contributors in one accessible reference, this book introduces focal therapy to all urologists, oncologists, and radiologists who are involved in the treatment of men with prostate cancer. |
| focal therapy prostate cancer nhs: Active Surveillance for Localized Prostate Cancer Laurence Klotz, 2018-08-26 This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the role of biomarkers and MRI in patient selection and management and details the world wide results of active surveillance. Specific chapters address communication and ethical issues, QOL outcomes, economic aspects, and psycho-social aspects of surveillance. The role of focal therapy for low risk disease is summarized, and the data supporting preventive interventions during surveillance reviewed. This text will serve as a very useful resource for physicians and researchers dealing with, and interested in this common malignancy, as it provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. |
| focal therapy prostate cancer nhs: Imaging and Focal Therapy of Early Prostate Cancer Thomas J. Polascik, 2012-12-02 Imaging and Focal Therapy of Early Prostate Cancer evaluates the scientific evidence for the evolving trend to treat low to intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, are discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on tumor stage shift towards early stage disease with an increase in unilateral versus bilateral cancers validated by final pathology assessment of large prostatectomy series. Current and new approaches to image cancer foci within the prostate (3-Dimensional contrast-enhanced transrectal ultrasonography, multiparametric magnetic resonance image with spectroscopy, ETC) are presented along with biopsy techniques to map prostate cancer. Patient selection, treatment strategy, outcomes and safety concerns that may provide acceptable cancer control and improved quality of life for patients are all covered in detail. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer is a resourceful volume beneficial to practitioners specializing in the treatment and management of prostate cancer. |
| focal therapy prostate cancer nhs: Adaptive Radiation Therapy X. Allen Li, 2011-01-27 Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an |
| focal therapy prostate cancer nhs: Focal Therapy of Prostate Cancer Stefan Thüroff, Christian G. Chaussy, 2015-03-20 This book provides a 2015 state of the art update on the hot topic of focal prostate cancer therapy, which offers a means of preserving the prostate and avoiding major side-effects associated with conventional treatment strategies. In so doing, focal therapy meets the desire of many patients, especially those with low-risk disease, to avoid or postpone radical therapies in order to preserve quality of life. A wide range of aspects are covered, including the role of imaging-guided targeted biopsies, the pros and cons of surveillance in comparison with focal therapy, focal hemiablation and focal salvage therapy, multifocal therapies, focal cryotherapy. The potential role of various new diagnostic technologies as well as specific therapeutic devices as Focal.One robotic high-intensity focused ultrasound are explained. The authors are all international experts who are long-term proponents of non-invasive treatment of prostate cancer. Focal Therapy of Prostate Cancer will be an invaluable source of information for urologists, oncologists, radiation oncologists, and general practitioners, and also for patients wishing to learn more about this new treatment option. |
| focal therapy prostate cancer nhs: Interventional Urology Ardeshir R. Rastinehad, David N. Siegel, Bradford J. Wood, Timothy McClure, 2021-11-17 This updated text provides a concise yet comprehensive and state-of-the-art review of evolving techniques in the new and exciting subspecialty of interventional urology. Significant advances in imaging technologies, diagnostic tools, fusion navigation, and minimally invasive image-guided therapies such as focal ablative therapies have expanded the interventional urologists’ clinical toolkit over the past decade. Organized by organ system with subtopics covering imaging technologies, interventional techniques, recipes for successful practice, pitfalls to shorten the learning curves for new technologies, and clinical outcomes for the vast variety of interventional urologic procedures, this second edition includes many more medical images as well as helpful graphics and reference illustrations. The second edition of Interventional Urology serves as a valuable resource for clinicians, interventional urologists, interventional radiologists, interventional oncologists, urologic oncologists, as well as scientists, researchers, students, and residents with an interest in interventional urology. |
| focal therapy prostate cancer nhs: Oxford Handbook of Urology John Reynard, Simon Brewster, Suzanne Biers, 2013-02-28 Fully revised for the third edition, the Oxford Handbook of Urology provides an excellent, informative and comprehensive overview of the entire spectrum of urology. |
| focal therapy prostate cancer nhs: Improving Diagnosis in Health Care National Academies of Sciences, Engineering, and Medicine, Institute of Medicine, Board on Health Care Services, Committee on Diagnostic Error in Health Care, 2015-12-29 Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety. |
| focal therapy prostate cancer nhs: Surgical Procedures for Core Urology Trainees Sanchia Goonewardene, Raj Persad, 2017-10-24 This book aims to give junior urologists in training an idea of how to assemble equipment required for core urology procedures on a global level. This includes what to do pre-operatively, surgical indications and techniques, what to do post operatively, and complications that may occur. It can be daunting taking up a post as a surgical trainee despite supervision of seniors. This book will help in instilling competence and confidence in the trainee with step by step descriptions of key specialty procedures and their variations. Important practical clinical anatomy will be illustrated as well as an emphasis on safety. |
| focal therapy prostate cancer nhs: Urological Pathology Mahul B. Amin, John Eble, David Grignon, John Srigley, 2013-11-14 Knowledge in the field of urologic pathology is growing at an explosive pace. Today’s pathologists, specialists, and residents require a comprehensive and authoritative text that examines the full range of urological diseases and their diagnosis. Written by recognized leaders and educators in the field, the text provides readers with a detailed understanding of all diagnostic aspects of urological disease. Inside this unique resource, readers will explore a broad spectrum of practical information—including etiology, diagnostic criteria, molecular markers, differential diagnosis, ancillary tests, and clinical management. This is sure to be the new definitive text for urological pathology! |
| focal therapy prostate cancer nhs: Technical Aspects of Focal Therapy in Localized Prostate Cancer Eric Barret, Matthieu Durand, 2015-01-29 Focal therapy is a promising option for selected patients who have localized low or intermediate-risk prostate cancer, providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible. Numerous cohort studies have already investigated multiple focal techniques, such as cryotherapy, high-intensity focused ultrasound, brachytherapy, photodynamic therapy, laser therapy, irreversible electroporation and cyberknife methods, all of which have demonstrated positive oncological outcomes with 70 to 90 % negative follow-up biopsy. These various ablative techniques have produced only minor side-effects concerning urinary function, a low rate of erectile dysfunction, and have demonstrated a limited rectal toxicity. As a result, the primary end-point has now shifted and a new strategy needs to be established for patient follow-up and for defining treatment failure. Written by international experts in the field, this book is mainly focused on new techniques, all of which are amply illustrated. Technical Aspects of Focal Therapy in Localized Prostate Cancer will be of great practical value to all urologists and oncologists. |
| focal therapy prostate cancer nhs: Prostate Cancer Prevention Jack Cuzick, Mangesh A. Thorat, 2014-02-15 Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers. |
| focal therapy prostate cancer nhs: Prostate Cancer Survivorship Sanchia S. Goonewardene, Raj Persad, 2018-12-21 This book provides information on a range of issues related to prostate cancer survivorship, including; psychosexual care, health related quality of life, treatment, follow-up care, new psychosexual pathways, and acute and chronic co-morbidities. The book also covers the needs and challenges in survivorship care, the requirements of care, the future of survivorship care, and role of patient conferences. This book aims to give oncologists, urologists, and specialist nurses help in how to manage patients in the prostate cancer survivorship phase. This guidance is based on real life experiences handling prostate cancer survivorship, and is developed further through utilising the views of both health care professionals and patients. |
| focal therapy prostate cancer nhs: Prostate Cancer: A Comprehensive Perspective Ashutosh Tewari, 2013-04-05 Prostate cancer is the commonest male cancer with over 5 million survivors in US alone. Worldwide, the problem is staggering and has attracted significant attention by media, scientists and cancer experts. Significant research, discoveries, innovations and advances in treatment of this cancer have produced voluminous literature which is difficult to synthesize and assimilate by the medical community. Prostate Cancer: A Comprehensive Perspective is a comprehensive and definitive source which neatly resolves this problem. It covers relevant literature by leading experts in basic science, molecular biology, epidemiology, cancer prevention, cellular imaging, staging, treatment, targeted therapeutics and innovative technologies. Prostate Cancer: A Comprehensive Perspective, is a valuable and timely resource for urologists and oncologists. |
| focal therapy prostate cancer nhs: An Insider's Perspective of Prostate Cancer Robert Alexander ('Frank') Gardiner, 2022-09-03 An Insider's Perspective of Prostate Cancer: Understanding Effects, Management Options and Consequences provides scientifically based information on the management and treatment of prostate cancer. The text is designed to be neither prescriptive nor proscriptive, providing succinct, yet comprehensive details in 'bite size chunks' for ready assimilation and application. Sections cover recent approaches the prostate cancer landscape has made by providing background statistical and anatomical information that is followed by relevant genetic, immunological and background data. The book then proceeds to explain the mechanisms involved with cancer development and the spread and metastases that can occur in a minority of those diagnosed. In addition to acknowledging the importance of psychological effects of diagnosis and management interventions, the undervalued benefits of exercise are also emphasized, including information on holistic management. This comprehensive approach makes this a perfect reference for up-to-date information on all aspects of prostate cancer and its management. - Provides succinct, yet comprehensive coverage on the management and treatment of prostate cancer and subsequent consequences for patients - Reviews how prostate cancers change and how treatments can adapt - Delivers guidance on how to assess information with ranking in terms of levels of evidence, thus enabling the evaluation of critical reports and claims made in relation to prostate cancer and other conditions |
| focal therapy prostate cancer nhs: Evolving Trends in Kidney Cancer Sashi S. Kommu, Inderbir Gill, 2020-07-22 Kidney cancer imposes a significant cancer burden and its incidence continues to rise globally. Mortality in advanced kidney cancer remains high despite oncological, surgical and multimodal optimisation. Genetic associations, heterogeneity and limitations in early diagnosis through lack of optimal biomarkers add to the challenges. Over the last two decades there has been an exponential increase in diagnostic and therapeutic advances in the management of kidney cancer. The coupling of scientific advances in engineering and technology with oncological therapeutics has recently ushered a renewed optimism. The role of minimally invasive approaches through focal therapy and surgical extirpation using the robotic platform has been unprecedented and paramount. Virtual augmentation and mixed reality platforms have proved useful supplementary tools in surgical planning. The role of surgical simulation and training in development of surgeons with the optimal skill set is essential to provide optimal care. This book is the first in a series that explores the evolving trends in kidney cancer. The focus of the book is broad and includes topics ranging from immunotherapy to surgical simulation. Some chapters explore leading edge concepts while others capture the evolving trends and future concepts. The Editors aim to stimulate the readers to explore the key concepts and to encourage research and innovation along the main themes presented. |
| focal therapy prostate cancer nhs: Urological Tests in Clinical Practice Nagaraja P. Rao, Shalom J. Srirangam, Glenn M. Preminger, 2007-03-11 This is a concise pocket guide to urological investigative procedures. It reviews the indications and pitfalls of tests before they are requested and suggests which investigations should be performed in individual urological conditions. Cross-sectional and other radiological images help illustrate the main diagnostic features, and diagrams and graphs illustrate the main points of the test. Bulleted items at the end of chapters are highlighted in a ‘box’ – useful during a busy ward round, out-patient clinic, or for last-minute consultation prior a viva examination. |
| focal therapy prostate cancer nhs: Urologic Principles and Practice , 2020 This volume focuses on aspects of urology which are often forgotten in contemporary practice, but are nevertheless the subject of incremental advances and form the basis of much of the non-oncological practice. It covers numerous topics including laparoscopy. |
| focal therapy prostate cancer nhs: Urological Cancer Management Said Abdallah Al-Mamari, Salim Said Al-Busaidy, 2015-05-14 The authors aim to provide essential information on various clinical cases on urological cancers. The main messages are well referenced and the texts phrasing is written in a simple and user-friendly style. The book also contains summarizing tables and high quality original pictures. Several expert panels (American Urologists Association, European Association of Urologists, Association Française des Urologues, etc) are proposing guidelines aiming at providing detailed recommendations to the Urologists facing difficult urological scenarios and no significant discordance exist between them since they are all based on the existing published studies dealing with different aspects of the urological cancers. |
| focal therapy prostate cancer nhs: Campbell Walsh Wein Urology Alan W. Partin, Craig A. Peters, Louis R. Kavoussi, Alan J. Wein, Roger R. Dmochowski, 2020-03-02 From the basic science underpinnings to the most recent developments in medical and surgical care, Campbell-Walsh-Wein Urology offers a depth and breadth of coverage you won't find in any other urology reference. Now in three manageable volumes, the revised 12th Edition is a must-have text for students, residents, and seasoned practitioners, with authoritative, up-to-date content in an intuitively organized, easy-to-read format featuring key points, quick-reference tables, and handy algorithms throughout. Features shorter, more practical chapters that help you find key information quickly. Includes new chapters on Urinary Tract Imaging: Basic Principles of Nuclear Medicine · Ethics and Informed Consent · Incisions and Access · Complications of Urologic Surgery · Urologic Considerations in Pregnancy · Intraoperative Consultation · Special Urologic Considerations in Transgender Individuals · and more. Covers hot topics such as minimally invasive and robotic surgery; advancements in urologic oncology, including innovative therapeutics for personalized medicine; new approaches to male infertility; technological advances for the treatment of stones; and advances in imaging modalities. Incorporates current AUA/EAU guidelines in each chapter as appropriate Updates all chapters with new content, new advances, and current references and best practices. Extensively updated chapters include Urological Immunotherapy, Minimally Invasive Urinary Diversion, and Updated Focal Therapy for Prostate Cancer. Features more than 175 video clips, including all-new videos on perineal ultrasound, abdominoplasty in prune belly syndrome, partial penectomy, low dose rate brachytherapy, and many more. Written and edited by key opinion leaders, reflecting essential changes and controversies in the field. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. |
| focal therapy prostate cancer nhs: Basic Clinical Radiobiology Michael C. Joiner, Albert J. van der Kogel, 2018-08-28 Basic Clinical Radiobiology is a concise but comprehensive textbook setting out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics, and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists. |
| focal therapy prostate cancer nhs: Accuracy Requirements and Uncertainties in Radiotherapy International Atomic Energy Agency, 2017-04-12 Accuracy requirements in radiation oncology have been defined in multiple publications; however, these have been based on differing radiation technologies. In the meantime, the uncertainties in radiation dosimetry reference standards have been reduced and more detailed patient outcome data are available. No comprehensive literature on accuracy and uncertainties in radiotherapy has been published so far. The IAEA has therefore developed a new international consensus document on accuracy requirements and uncertainties in radiation therapy, to promote safer and more effective patient treatments. This publication addresses accuracy and uncertainty issues related to the vast majority of radiotherapy departments including both external beam radiotherapy and brachytherapy. It covers clinical, radiobiological, dosimetric, technical and physical aspects. |
| focal therapy prostate cancer nhs: Physical Activity and Cancer Kerry S. Courneya, Christine M. Friedenreich, 2010-11-26 This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care. |
| focal therapy prostate cancer nhs: Post-Prostatectomy Incontinence Ajay Singla, Craig Comiter, 2017-06-28 This text provides a comprehensive, state – of – the art review of this new and emerging field, as the number of men who suffer from post-prostatectomy incontinence increases by greater than 10,000 per year. How to evaluate and manage this devastating disorder has become a necessary part of nearly every urologic practice. This book serves a valuable resource for physicians with an interest in managing patients with post-prostatectomy incontinence. In addition, treatment includes algorithms and suggested office evaluation that will help guide conservative management that is appropriate for most patients. The text provides insight into the history of male incontinence surgery, as well as the current surgical techniques for the operative management of post-prostatectomy incontinence in those who fail conservative management. This text reviews current data regarding surgical outcomes for the most common and newly developed incontinence procedures, as well as step-by-step descriptions of the key surgical steps necessary for success. All chapters are written by world renowned experts in this field and include the most up to date clinical information. |
| focal therapy prostate cancer nhs: Urological Oncology Vinod H. Nargund, Derek Raghavan, Howard M. Sandler, 2015-01-17 As a professional resource for all doctors, oncologists and urologists involved in the care of uro-oncology patients, this book puts emphasis on developing advanced practice with in-depth discussions to support evidence based, patient focused care. Urological Oncology, Second Edition offers an updated multi-disciplinary and multi professional approach to the assessment, diagnosis, treatment and follow-up care of patients being investigated and treated for urological malignancies. Mainly aimed at oncologists and urologists, it is also useful for general physicians as well as trainee nurses and nurse practitioners in urology / urological oncology. |
| focal therapy prostate cancer nhs: Physical Properties of Tissues Francis Duck, 2013-10-22 This unique reference book describes quantitatively the measured and predicted values of all the physical properties of mammalian tissue. Reported measurements are thoroughly documented and are complemented by a range of empirical mathematical models which describe the observed physical behavior of tissue.**Intended as a broad-ranging reference, this volume gives the bioengineer, physicist, radiologist, or physiologist access to a literature which may not be known in detail. It will also be of value for those concerned with the study of a range of environmental radiation hazards.Most extensive compilation of values of physical properties of tissue**Presents data for thermal, optical, ultrasonic, mechanical, x-ray, electrical, and magnetic resonance properties**Comprehensive bibliography |
| focal therapy prostate cancer nhs: Spinal Neurosurgery James Harrop, Christopher Maulucci, 2018-12-18 Neurosurgery by Example: Key Cases and Fundamental Principles provides case-based, high yield content for the spine surgeon and neurosurgeons preparing for the American Board of Neurological Surgeons oral examination. It covers a wide array of spinal pathologies with their presentation, diagnosis, and treatment plans. Postoperative and complication management strategies are offered as well in order to prepare surgeons who can then provide comprehensive patient care for complex spine conditions.--Provided by publisher. |
| focal therapy prostate cancer nhs: ABC of Prostate Cancer Prokar Dasgupta, Roger S. Kirby, 2011-10-19 Prostate cancer is the most common cancer in men in the UK and US and the second most common worldwide. The ABC of Prostate Cancer provides fully illustrated guidance on the treatment and management of prostate cancer. It covers the biology, anatomy, and pathology of prostate cancer, screening, and active surveillance and monitoring. It presents an assessment of treatment options including prostatectomy, bracytherapy, chemotherapy and immunotherapy, along with modern diagnostic tests and an overview of new approaches to prostate cancer. With an international author team, the ABC of Prostate Cancer is ideal for general practitioners, family physicians, specialist nurses, junior doctors, medical students and others working with prostate cancer patients and their families. |
| focal therapy prostate cancer nhs: Prostate Cancer Ashutosh K. Tewari, Peter Whelan, John D. Graham, 2013-12-23 Do you manage patients with prostate cancer? Could you use an expert guide examining all possible management options? Prostate Cancer: diagnosis and clinical management providesurologists and oncologists of all levels with up-to-date, evidence-based guidance to the diagnosis, treatment and clinical management of a disease which accounts for a quarter of all cancers affecting men. Designed to be as practical and accessible as possible, leading experts discuss key issues in prostate cancer management and examine how to deliver best practice in the clinical care of their patients. Topics covered include: What must be considered when counseling newly-diagnosed cancer patients Radical surgery options for prostate cancer Novel therapies for localized prostate cancer How should metastatic prostate cancer be diagnostic and managed What are the best methods of administering end of life care for the patient Brought to you by a highly experienced editor team, and containing key points, management algorithms, practice tips and the latest AUA and EAU clinical guidelines, this is the ideal consultation tool for doctors both on the wards and in the office. |
| focal therapy prostate cancer nhs: Autoimmune Neurology , 2016-03-11 Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. - Includes comprehensive coverage of autoimmune neurology - Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders - Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities |
| focal therapy prostate cancer nhs: Radioguided Surgery Giuliano Mariani, Armando E. Giuliano, H. William Strauss, 2010-05-10 This multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients. Comprehensive coverage is provided on all aspects of radioguided surgery. Practical information is readily accessible and throughout there is an emphasis on improved decision making. Tables present the indications, performance, and interpretation of procedures at a glance. A wealth of illustrations, including a full-color insert, enhances the application of new concepts. |
| focal therapy prostate cancer nhs: Imaging of Complications and Toxicity following Tumor Therapy Hans-Ulrich Kauczor, Tobias Bäuerle, 2015-11-09 Depending on their mechanism of action, the cytotoxic and targeted drugs and radiotherapy employed in oncologic treatment may cause complications and toxicities in many organ systems, with variable radiologic presentations. This comprehensive and excellently illustrated book covers the basics of therapy-induced complications and toxicities in oncologic patients, identifies their consequences for all the major organs, and describes the imaging of these impacts by means of the various radiologic modalities. By familiarizing radiologists with the most frequent and prominent toxicities that are recognizable on radiologic imaging following tumor therapy, it will facilitate identification of their early manifestations and permit differential diagnosis based on relevant findings. |
| focal therapy prostate cancer nhs: Oncologic Critical Care Joseph L. Nates, Kristen J. Price, 2019-10-30 This major reference work is the most comprehensive resource on oncologic critical care. The text reviews all significant aspects of oncologic ICU practices, with a particular focus on challenges encountered in the diagnosis and management of the critically ill cancer patient population. Comprised of over 140 chapters, the text explores such topics as the organization and management of an oncologic ICU, diseases and complications encountered in the oncologic ICU, multidisciplinary care, surgical care, transfusion medicine, special patient populations, critical care procedures, ethics, pain management, and palliative care. Written by worldwide experts in the field, Oncologic Critical Care is a valuable resource for intensivists, advance practice providers, nurses, and other healthcare providers, that will help close significant knowledge and educational gaps within the realm of medical care for critically ill cancer patients. |
| focal therapy prostate cancer nhs: Comparative Oncology Alecsandru Ioan Baba, Cornel Cătoi, 2007 |
| focal therapy prostate cancer nhs: Imaging and Focal Therapy of Early Prostate Cancer Thomas J. Polascik, 2018-08-07 This text encompass an up-to-date, comprehensive review of the state-of-the-art for gland preserving therapies. Fully updated and revised, this text evaluates the scientific evidence for the evolving trend to treat intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, is discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on patient selection and outcomes utilizing both advanced imaging techniques and pathologic evaluation. Current and new approaches to image cancer foci within the prostate (multiparametric ultrasonography, multiparametric magnetic resonance image, etc) are presented along with various biopsy techniques, including robotics to map prostate cancer. Patient selection based on imaging and genomic classification, adjuvants to enhance therapy, treatment strategy, outcomes and patient centered concerns is discussed, providing an acceptable balance between cancer control and improved quality of life for patients. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer, Second Edition is designed as a comprehensive resource for urologists, radiation oncologists, medical oncologists, radiologists, uropathologists, molecular biologists, biomedical engineers, other clinicians –- residents, fellows, nurses and allied professionals -- and researchers with an interest in the diagnosis and novel treatment of prostate cancer. It will provide insight into the latest research and clinical applications of image-guided diagnosis and minimally invasive focal, gland-preserving treatment for prostate cancer. |
| focal therapy prostate cancer nhs: Image Guided Prostate Cancer Treatments Robert L. Bard, Jurgen J. Fütterer, Dan Sperling, 2013-11-18 Image-Guided Prostate Cancer Treatments is a comprehensive reference and practical guide on the technology and application of ultrasound and MRI in the male pelvis, with special attention to the prostate. The book is organized into three main sections, the first of which is devoted to general aspects of imaging and image-guided treatments. The second section provides a systematic overview of the application of ultrasound and MRI to the diagnosis and treatment of diseases of the lower urinary tract. Performance of the ultrasound and MRI studies is explained, and the normal and abnormal pathological anatomy is reviewed. Correlation with the ultrasound in the same plane is provided to assist in understanding the MRI sequences. Biopsy and interventional procedures, ultrasound-MRI fusion techniques, and image-guided therapies, including focused ultrasound, photodynamic therapy, microwave and laser ablation, are all fully covered. The third section focuses on securing treatment effectiveness and the use of follow-up imaging to ensure therapeutic success and detect tumor recurrence at an early stage, which is vital given that prompt focal treatment of recurrence is very successful. Here, particular attention is paid to the role of Doppler ultrasound and DCE-MRI technologies. This book, containing a wealth of high-quality illustrations based on high-end equipment, will acquaint beginners with the basics of prostate ultrasound and MRI, while more advanced practitioners will learn new skills, means of avoiding pitfalls, and ways of effectively relating the imaging and image-guided treatments to the clinical situation. The information provided will permit a tailored approach in dealing with specific pathologic issues. |
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Focal Ablation Targeted to the Index Lesion in Multifocal …
University College London Hospitals NHS Foundation Trust, London, UK EUROPEAN UROLOGY 68 (2015) 927–936 ... Article history: Accepted January 27, 2015 Keywords: Focal therapy …
Comparative effectiveness analyses of salvage prostatectomy …
Ablative therapy, such as focal therapy, cryotherapy or electroporation, aims to treat clinically significant prostate cancer with reduced treatment-related toxicity. Up to a third of patients may …
Prostate Radiofrequency Focal Ablation (ProRAFT) Trial: A …
Conclusions: Focal therapy of significant localized prostate cancer associated with a magnetic resonance imaging lesion using bipolar radiofrequency showed early efficacy to ablate cancer …
Primary Whole-gland Ablation for the Treatment of Clinically …
Ablation therapy Best practice statement Cryotherapy High-intensity focused ultrasound Functional outcomes Focal Therapy Society Oncological outcomes Prostate cancer Whole …
CHRONOS: Comparative health research outcomes of novel …
Nov 13, 2019 · Arm 2 (Intervention): Focal therapy alone (high intensity focused ultrasound [HIFU] or cryotherapy as per physician and centre choice). A second focal therapy session in-field, or …
1545 Review Article on Prostate Imaging and Focal Therapy …
Email: christopher.khoo@nhs.net. Abstract: Although radiotherapy to the prostate for cancer is effective, recurrence occurs in 10–15% within 5 years. Traditional salvage treatments for men …
Detailing Sexual Outcomes After Focal Therapy for Localised …
Sexual Outcomes After Focal Therapy for Localised Prostate Cancer: A Systematic Review and Meta-analysis Gaelle Fiarda,b,c,d,*, Aminah Chowdhurye,f, Aneirin R. Pottere,f, Celina J ...
Clinical Guidance for BRCA Gene Testing for ... - NHS Wales …
Prostate cancer is the commonest cancer in men in the UK, with approximately 50,000 men diagnosed annually (The Royal College of Surgeons on England, 2021). 13% of men present …
ROBOTIC ASSISTED RADICAL PROSTATECTOMY AFTER …
Urology Centre, Guy's and St Thomas NHS Foundation Trust, London, UK b. Department of Urology, Kings College Hospital, London, UK ... Robotic surgery after focal therapy for prostate …
Edward J Bass [1,2], Hashim U. Ahmed [1,2] - University …
focal therapy - we deem the seven sins - that require further interrogation. Key words Prostate cancer; Focal therapy; Arguments for; Arguments against Introduction Radical treatments such …
Multi-disciplinary Team (MDT) Guidance for Managing …
4 Integrated care and clinical governance • The effective functioning of the MDT and tailored care pathways for patients will support the (now routine) clinical governance procedures …
Prostate Cancer Training and Update Day 2024
Prostate Cancer Training and Update Day 2024 An essential update from national and international experts on Prostate Cancer Diagnosis and Management. ... Chair: Prof Alan …
Prostate high dose rate brachytherapy - patient information
treat prostate cancer with the intention of curing it. A computer controlled machine called a microselectron pushes a single radioactive iridium pellet into small tubes placed into the …
Focal Therapy in Primary Localised Prostate Cancer: The …
Position Paper Focal Therapy in Primary Localised Prostate Cancer: The European Association of Urology Position in 2018 Henk G. van der Poela,*, Roderick C.N. van den Bergha, Erik Briersb, …
The Role of Focal Therapy in the Management of Localised …
Review – Prostate Cancer The Role of Focal Therapy in the Management of Localised Prostate Cancer: A Systematic Review Massimo Valerioa,b,c,y,*, Hashim U. Ahmeda,b,y, Mark …
NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE
Services Division, NHS National Services Scotland and PHS Scotland April 2020 and April 2021). There can be many impacts on men of living with prostate cancer. There can be ... cancer - …
Evaluation of functional outcomes after a second focal …
functional outcomes, high-intensity focal ultrasonography, localized prostate cancer, #ProstateCancer, #PCSM Introduction Primary focal therapy to treat localized prostate cancer …
Health technology assessment in evolution – focal therapy …
in evolution – focal therapy in localised prostate cancer Expert Rev. Anticancer Ther. 14(11), 1359–1367 (2014) Massimo Valerio*1–3, Mark Emberton1,2, Eric Barret4, Daniel Eberli5, ...
OPCS-4.6 codes agreed with the NHS Classifications - NICE
Focal therapy using high-intensity focused ultrasound for localised prostate cancer M71.1 High intensity focused ultrasound of prostate Plus Y53.2 Approach to organ under ultrasonic control …
Focal Ablation of Early-Stage Prostate Cancer
Stage Prostate Cancer Candidate Selection, Treatment Guidance, and Assessment of Outcome Eric Edison, MA(Cantab), MBBS, ... WC1E 6AU, UK; c Department of Urology, Whittington …
Focal Therapy for Prostate Cancer: Recent Advances and …
rationale for focal therapy in localized prostate cancer, examines the major therapy modalities, and addresses future directions. Introduction Prostate cancer, which is estimated to have …
EAU and NICE guidelines for the diagnosis and management …
Prostate cancer (PCa) is the most common cancer in men both in the United Kingdom (UK) and Europe, accounting ... philip.cornford@rlbuht.nhs.uk 720353 URO …
Imaging and Focal Therapy of Early Prostate Cancer
Imaging and Focal Therapy of Early Prostate Cancer Current Clinical Urology Series Editor: Eric A. Klein Urology 9 781627 031813 ISBN 978-1-62703-181-3 Polascik Ed. Imaging and Focal ...
External validation of a risk model predicting failure of salvage …
ablation, cryotherapy, failure, focal therapy, high-intensity focussed ultrasound, prediction model, prostate cancer, radiotherapy, recurrence, salvage Introduction Radiotherapy (RT) is a …
A randomised controlled trial of Partial prostate Ablation …
intermediate-risk, unilateral clinically localised prostate cancer Participant Information Sheet Version 4.0, 15 May 2024 ... Focal therapy (partial ablation) for prostate cancer can be used by …
Job Description - Trac
complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local ... The role is fully attached to the …
Terapia focal en el cáncer de próstata: Situación Actual.
los estudios clínicos y revisiones bibliográficas que evaluaron la terapia focal primaria para el cáncer de próstata confirmado por biopsia. Se excluyeron los estudios de terapia focal de …
Treating prostate cancer
UK diagnosed with prostate cancer. One way . of dealing with the disease is through gaining knowledge and information. A diagnosis of ... Focal therapy – what is involved and what are …
Detailing sexual outcomes after focal therapy for localised …
Erectile dysfunction; prostate cancer; focal therapy Abstract Context: Focal therapy has emerged as a promising option to treat well-selected men with localised prostate cancer while …
Is there a role of PSMA-PET in focal therapy planning and
option for localized Prostate Cancer (PCa) [1, 2] aiming to reduce treatment-related morbidity and functional impairment associated with conventional whole-gland treat-
A Systematic Review of Focal Ablative Therapy for Clinically …
This is a repository copy of A Systematic Review of Focal Ablative Therapy for Clinically Localised Prostate Cancer in Comparison with Standard Management Options: Limitations of the …
Cancer control outcomes following focal therapy using HIFU …
3 60 Abstract 61 62 Background 63 Focal therapy aims to treat areas of cancer to confer oncological control whilst reducing 64 treatment-related functional detriment. 65 Objective 66 …
Focal radiotherapy boost to MR-visible tumor for prostate …
Keywords Focal boost · Localized prostate cancer · Magnetic resonance imaging · Intraprostatic lesion · External beam radiation therapy Introduction Standard radiation therapy (RT) for …
Histological characteristics of the index lesion in whole-mount …
focal therapy. Prostate Cancer and Prostatic Diseases, 2010, 10.1038/pcan.2010.16. hal-00539720 ... d Imperial College Healthcare NHS Trust, Charing Cross Hospital, Department …
Histological outcomes after focal high-intensity focused
The emergence of focal therapy as a potential and major shift in the way we manage localised prostate cancer is a highly debated area of research in uro-oncology. Whilst the concept of the …
Mental well‐being in prostate cancer: A multi‐institutional …
prostate cancer remains largely cross-sectional, providing a weaker evi-dence base for prognostic factor research. Therefore, the primary aim of this study was to explore the associa-tion …
Histological characteristics of the index lesion in whole-mount …
focal therapy. Prostate Cancer and Prostatic Diseases, 2010, 10.1038/pcan.2010.16. hal-00539720 ... d Imperial College Healthcare NHS Trust, Charing Cross Hospital, Department …
The Role of Focal Therapy in the Management of Localised …
Review – Prostate Cancer The Role of Focal Therapy in the Management of Localised Prostate Cancer: A Systematic Review Massimo Valerioa,b,c,y,*, Hashim U. Ahmeda,b,y, Mark …
Edward J Bass [1,2], Hashim U. Ahmed [1,2]
focal therapy - we deem the seven sins - that require further interrogation. Key words Prostate cancer; Focal therapy; Arguments for; Arguments against Introduction Radical treatments such …
PSA testing and the prostate cancer pathway
Focal therapy Incontinence 10-20% 10-20% 1-2% Impotence 30-60% 50-60% 5-10% Rectal toxicity 1% 5% 0.1% Salvage therapy at 5-10 years 15-20% 15-20% 15-20%. Conclusions The …
Prostate Cancer Tumour Features on Template Prostate …
tioners have argued that focal therapy is an alternative in men suitable for active surveillance [3,5,12], while others have argued that focal therapy should be investigated as a potential …
Nanoknife Electroporation Ablation Trial (NEAT): a prospective ...
VariousA number of sources of energy have been used to ablate prostate cancer in a focal manner. Across all series, pad-free continence, potency preservation, and absence of residual …
Anatomically versus biologically Ther Adv Urol unifocal …
proportion of patients with multifocal disease apparently suitable for focal prostate therapy. Keywords: focal therapy, index lesion ablation, prostate cancer Correspondence to: Markos …
Contemporary Clinical Trials
of an investigator-led UK multi-centre, single arm trial using HIFU to deliver focal therapy for men with localised prostate cancer. Methods: One-hundred and forty men with histologically proven …
Contemporary Clinical Trials
preservation and short-term cancer control. Large multi-centre trials are required to evaluate medium-term cancer control and reproduce functional recovery. We describe the study design …
Hormone therapy injections for prostate cancer - rwt.nhs.uk
• Hormone therapy is an effective treatment for prostate cancer • Hormone therapy can treat prostate cancer wherever the cancer cells are within the body. • Hormone therapy can be used …
Archive.org
v Foreword aradigm P Shift A critical change in how localized prostate cancer is managed is likely to take place due to the emerging combination of both new imaging ...
限局性前立腺癌に対する高密度焦点式超音波療法を用い …
Feb 18, 2024 · 績を明らかにすることにより，HIFUによるFocal Therapy のモダリティーとして，限局性前立腺癌の治療戦略の一つ となることが期待される． Focal therapy with high …
Focal therapy using cryoablation for localised prostate …
Treating localised prostate cancer using freezing (cryotherapy) ... funding are taken by local NHS bodies (primary care trusts and hospital trusts) after considering how well the procedure works …
Guidelines for the Management of Prostate Cancer - NHS …
1.2 Prostate cancer should also be considered in men with: erectile dysfunction haematuria lower back pain weight loss, especially in the elderly ... c. brachytherapy +/- hormone therapy d. …
