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| era endometrial receptivity analysis: Endometrial Gene Expression Joanne Kwak-Kim, 2020-11-21 The endometrium goes through cyclical changes under the influence of hormones, and immune effectors in the endometrium change their populations cyclically as well. Dynamic changes in immune effectors determine endometrial cytokine and chemokine milieus and, consequently, the endometrial immune response. Endometrial immune responses have been shown to be important for trophoblast invasion and early pregnancy. Indeed, dysregulated endometrial inflammatory immune responses are associated with reproductive failures, such as recurrent pregnancy losses, repeated implantation failure, and gynecological diseases with oncogenic potential. Hence, the investigation of endometrial gene expression may predict infertility, gynecological and oncological conditions. This book presents the state of the art in endometrial gene expression as well as recent developmental findings relating to reproduction and reproductive disorders. It begins with a review of the genetic regulation of urogenital tract formation and molecular mechanism underlying the physiology of menstrual cycle before moving on to the current and emerging technological advances in molecular biology. Endometrial gene expressions of immune inflammatory conditions, viral infection, metabolic and nutritional conditions, and reproductive disorders are then presented in following chapters. Examples of the use and interpretation of gene expression in clinical scenarios including recurrent pregnancy losses, infertility and multiple implantation failures are presented with currently available endometrial gene analysis. Utilizing the latest evidence and clinical guidelines, Endometrial Gene Expression will be a cutting-edge resource for gynecologist, reproductive immunologist, reproductive endocrinologists, obstetrician, maternal fetal medicine specialist and other health care providers in the field of reproductive medicine. |
| era endometrial receptivity analysis: Recurrent Implantation Failure Efstratios M. Kolibianakis, Christos A. Venetis, 2019-07-30 Implantation is a complex phenomenon, still not thoroughly understood, involving the embryo and the endometrium. Successful implantation is considered to stem from an efficient combination of various embryo and/or maternal factors. Repeated failure of any of these factors or of their combination might decrease the chance of implantation and eventually lead to recurrent implantation failure. Despite technological advances, only about a quarter of In Vitro Fertilization procedures will result in live birth, leading many couples to experience multiple failures. This text from international experts explores the various factors at play and offers a helpful summary of the state of knowledge to help guide clinicians in their management of this complex and important problem. Contents: What is Recurrent Implantation Failure? * The psychosocial aspects of recurrent implantation failure * The role of life-style factors in RIF * Endocrine causes of recurrent implantation failure * Congenital uterine anomalies and recurrent implantation failure * Immunological causes of recurrent implantation failure * Acquired uterine conditions, reproductive surgery, and RIF? * Thrombophilia: diagnosis and management in women with recurrent implantation failure * Andrological causes of RIF * Diagnostic evaluation of RIF? (Modalities and algorithm) * Optimizing embryo culture for RIF? * Optimizing endometrial receptivity for patients with recurrent implantation failure: The role of progesterone on the day of triggering final oocyte maturation * Is there a role of follicular phase LH and E2 on the day of triggering final oocyte maturation for embryo implantation? * Manipulating the endometrium: Can RIF be managed by inducing endometrial inflammation or by the use of novel research therapies * The embryo in RIF: Genetic selection and strategies for improving its implantation potential * Is oocyte donation efficient in patients with RIF? * Sperm donation and RIF? * Optimizing embryo transfer technique for RIF management * Proposed management of patients with recurrent implantation failure and directions for future research * When should patients abandon treatment? |
| era endometrial receptivity analysis: The Human Endometrium Carlo Bulletti, Erlio Gurpide, Carlo Flamigni, 1994 The structural, biochemical and clinical events related to menstruation, implantation, parturition, endometriosis, abnormal uterine bleeding and endometrial cancer are discussed in this comprehensive volume on the biological functions of the endometrium. New topics, such as the biochemical and molecular mechanisms regulating maternal embryonic interaction, are explored, and gynecologic endoscopy and therapeutic tools are discussed. The proceedings of the first conference is also available from the Academy, as volume 622 of The Annals of The New York Academy of Science. |
| era endometrial receptivity analysis: Modern Medical Genetics and Genomics Israel Gomy, 2019-12-18 The field of medical genetics and genomics has been constantly revolutionized by new breakthroughs, which bring more knowledge into the etiology and help improve the health care of individuals with either rare or common diseases. Nevertheless, as technologies evolve, novel challenges emerge, both technically and ethically, so they must be prudentially addressed. Among the myriad applications of genomics in medicine, this book depicts a glimpse of the advances achieved that have been leading us to the personalized/precision medicine era. |
| era endometrial receptivity analysis: How to Prepare the Egg and Embryo to Maximize IVF Success Gabor Kovacs, Anthony Rutherford, David K. Gardner, 2019-01-09 This comprehensive review of the factors that affect the harvesting and preparation of oocytes and the management of embryos will allow practitioners to make evidence-based decisions for successful IVF. The book reviews and re-considers the value of strategies and outcomes in the management of fertility and conception rates, centred on the production of oocytes, and successful development of the embryo. Authored by leading experts in the field, chapters engage with treatments and strategies that affect the production of oocytes and embryos, optimizing outcomes in the management of female fertility, conception rates, and live births. This vital guide covers controlled ovarian hyperstimulation, the role of AMH in determining ovarian reserve, and primary stimulation agents and the use of adjuncts. Integral for all clinicians and embryologists working in reproductive medicine units, readers are provided with evidence-based, comprehensive advice and review of all factors affecting the management of oocytes and the embryo that are vital for successful IVF cycles. |
| era endometrial receptivity analysis: Textbook of Assisted Reproduction Gautam Nand Allahbadia, Baris Ata, Steven R. Lindheim, Bryan J. Woodward, Bala Bhagavath, 2020-08-05 Groundbreaking, comprehensive, and developed by a panel of leading international experts in the field, Textbook of Assisted Reproduction provides a multidisciplinary overview of the diagnosis and management of infertility, which affects 15% of all couples around the world. The book aims to cover all aspects of assisted reproduction. Particular attention is given to topics such as the assessment of infertile couples; assisted reproductive techniques (ARTs) including ovulation induction, intra uterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (clinical and laboratory aspects); reproductive genetics; and obstetric and perinatal outcomes. |
| era endometrial receptivity analysis: Ultrasound Imaging in Reproductive Medicine Laurel A. Stadtmauer, Ilan Tur-Kaspa, 2019-07-19 Now in an updated edition, this is the most comprehensive book on modern ultrasound imaging in assisted reproductive technology (ART) and reproductive medicine. Fully revised and expanded, it covers emerging technologies possible with the improvement in ultrasound equipment. 3-D monitoring of ovarian follicles, bidirectional vibrant color and Doppler, and improved 3-D and 4-D imaging of reproductive structures are discussed. MRI-guided ultrasound procedures are covered, and comparisons of 3-D imaging with MRI imaging for uterine anomalies is reviewed with an emphasis on the advantages of 3-D performed in the gynecologist’s office, and as a less expensive modality. The overall approach of the original edition is maintained, starting with ultrasound safety and technique and diagnosis of the ovary, uterus and fallopian tubes (both normal and pathologic), followed by both male and female infertility and ART treatments and procedures. Ultrasound monitoring of follicular development, the endometrium, and as an aid in embryo transfer to maximize IVF success rates are reviewed. Topics new to this edition include updated information on the diagnosis of benign and malignant adnexal masses, 3-D follicle monitoring, and the diagnosis of adenomyosis and endometriosis, including deep inseminated endometriosis. Additionally, the evaluation of endometrial receptivity, the use of contrasts for fallopian tube patency, controversies regarding septate uterus versus arcurate uterus with the use of 3-D ultrasound, and 3-D ultrasound with saline infusion sonogram and early pregnancy ultrasound are all discussed. An excellent resource for reproductive medicine and ART specialists, gynecologists and ultrasonographers alike, Ultrasound Imaging in Reproductive Medicine, Second Edition covers all that clinicians need to know about the role of ultrasound, from the first time a woman comes into the clinic for treatment, including ART, to early pregnancy monitoring. See better, do ART better. |
| era endometrial receptivity analysis: A Textbook of Clinical Embryology Eliezer Girsh, 2021-05-06 Personnel working in assisted reproductive technology often lack the opportunities for dedicated training in the specialized techniques and technologies required for the procedures. As such, success in the form of live birth rates can range from over 50% to less than 10% per treatment cycle. This comprehensive introductory textbook is an essential resource for trainee embryologists, medical students and nurses. The recent revolutions in biotechnology and molecular biology involved in delivering assisted reproductive services are thoroughly discussed. Basic knowledge such as the development and physiology of both male and female reproductive systems is covered, with practical aspects of IVF including gamete and embryo manipulation, cryopreservation and genetic testing explained in detail. A full description of the optimal structure and management of the IVF laboratory is given, helping ensure procedures are safe and effective. Extensive and highly detailed colour illustrations bring the content to life and aids readers in their understanding. |
| era endometrial receptivity analysis: Recurrent Implantation Failure Jason M. Franasiak, Richard T. Scott Jr., 2018-04-03 This unique text discusses the wide range of causes and pathophysiologic conditions contributing to recurrent implantation failure (RIF) and the current treatment approaches to best approach this challenging patient population. Beginning with a presentation of the mechanism of normal implantation, the physiologic synchrony between embryo and endometrium, and the roles of both gametes and embryos in RIF, the book then examines the various genetic, immune and environmental factors involved. Abnormalities of the hematologic and endocrine system, as well as those of the anatomy and microbiome, are described in detail. Last but no less important, the psychological stress and treatment of patients experiencing RIF is discussed. Assisted reproductive technology (ART) success has increased substantially over the past three decades. However, despite these advances, recurrent implantation failure is still a common issue confronting patients and clinicians, and RIF represents one of the greatest challenges in ART and remains a source of frustration and disappointment for patients, clinicians, and researchers involved in the process. Providing an in-depth investigation into the pathophysiology and biological mechanisms of RIF and its clinical management, this will be an excellent resource for reproductive endocrinologists and infertility specialists. |
| era endometrial receptivity analysis: Silent Sorority Pamela Mahoney Tsigdinos, 2009 In an era of fertility for all and dominated by Mom's Clubs and helicopter parents, Silent Sorority reveals the difficult business of rebuilding a life when infertility treatments prove fruitless. |
| era endometrial receptivity analysis: The Endometrium Stanley R. Glasser, John D. Aplin, Linda C. Giudice, Siamak Tabibzadeh, 2002-05-16 The Endometrium is devoted to a comprehensive multi-disciplinary account of the uterine endometrium. This book is the first to define the regulatory biological interrelationships between epithelial and stromal cell phenotypes, endothelial cells, extracellular matrix and immunobiological elements. It highlights their relevance to clinical conditions |
| era endometrial receptivity analysis: The Endometrial Factor Carlos Simbfon, Linda Giudice, 2017 |
| era endometrial receptivity analysis: Reproductomics José A. Horcajadas, Jaime Gosálvez, 2018-07-13 Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine. - Thoroughly discusses how genomics and other omics approaches aid clinicians in various areas of reproductive medicine - Identifies specific genomic and molecular factors of translational value in treating infertility and analyzing patient data - Features chapter contributions by leading international experts |
| era endometrial receptivity analysis: Culture Media, Solutions, and Systems in Human ART Patrick Quinn, 2014-03-27 This volume describes culture media and solutions used in human ART; how they have been developed for in vitro human pre-implantation embryo development, the function and importance of the various components in media and solutions and how they interact, and how the systems in which these are used can influence outcomes. Chapters discuss inorganic solutes, energy substrates, amino acids, macromolecules, cytokines, growth factors, buffers, pH, osmolality, and the interaction of these parameters. The role of incubators and other physical factors are reviewed, along with the relevance and prospects of emerging technologies: morphokinetic analysis using time-lapse imaging and dynamic fluid incubation systems. Results of prospective randomized trials are emphasized to ascertain the added value of these techniques for selecting viable embryos. This comprehensive guide will be invaluable for embryologists, physicians and all personnel involved in the fluid products used in human ART seeking to optimize their successful use of these components. |
| era endometrial receptivity analysis: Ultrasonography in Reproductive Medicine and Infertility Botros R. M. B. Rizk, 2010-03-25 Nowhere has the impact of ultrasonography been more dramatic than in reproductive medicine, particularly in the diagnosis of female and male infertility, the management of assisted reproductive procedures and the monitoring of early pregnancy. This authoritative textbook encompasses the complete role of ultrasonography in the evaluation of infertility and assisted reproduction. Covering every indication for ultrasonography in assisted reproductive technology, this will prove an invaluable resource in the evaluation of the infertile patient and optimization of the outcome of treatment. The interpretation of images to improve fertility and reproductive success is emphasized throughout. Ultrasonography in Reproductive Medicine and Infertility is essential reading for clinicians working both in IVF clinics and in office practice. It will be particularly useful to gynecologists, infertility specialists, ultrasonographers and radiologists working in reproductive endocrinology and infertility, assisted reproductive technology, ultrasonography and radiology. |
| era endometrial receptivity analysis: In Vitro Fertilization and Embryo Transfer Don P. Wolf, 2012-12-06 The use of human in vitro fertilization in the management of infertility is the outgrowth of years of laboratory observations on in vitro sperm-egg interaction. The editors of this work have themselves contributed significantly to basic knowledge of the mammalian fertilization process. The observations of Don Wolf on sperm penetration, the block to polyspermy and, most recently, sperm hyperactivation in the monkey and human, Gregory Kopf's elucidation of the mechanisms of sperm activation during penetration and the reciprocal dialogue between sperm and egg, and Barry Bavister's definition of culture conditions and requirements necessary for in vitro oocyte maturation, fertilization and development in model mammalian systems including nonhuman primates have contributed greatly to our understanding of the mammalian fertilization process. Wolf, Kopf and Gerrity have enjoyed substantial interaction with clinicians in Departments of Obstetrics and Gynecology and have been directly involved with successful IVF programs. Both Wolf and Kopf have served as research scientists in the Division of Reproductive Biology at the University of Pennsylvania, which, for more than 22 years, has fostered co-mingling of clinically oriented and basic science faculty. It is through such interaction, which clearly exists at many institutions including the University of Wisconsin, that the process of technology transfer is best served. Without an exquisitely coordinated laboratory, there can be no consistent success in human in vitro fertilization. Quality control is pivotal, but close collaboration between the laboratory and the clinic is also essential as information is shared and correlated. |
| era endometrial receptivity analysis: Human Preimplantation Embryo Selection Jacques Cohen, Kay Elder, 2007-09-26 The most profound dilemma in assisted reproduction to date is the inability to recognize potentially viable embryos before their replacement into the reproductive tract. Application of increasingly advanced new technology has allowed the field of embryo evaluation to evolve rapidly and dramatically over the past five years.Human Preimplantation Emb |
| era endometrial receptivity analysis: Towards Reproductive Certainty: Fertility and Genetics Beyond 1999: The Plenary Proceedings of the 11th World Congress R. Jansen, D. Mortimer, 1999-04-15 This is a forward-looking clinical reference of definitive authority on today's headline controversies surrounding in vitro fertilization (IVF) and reproductive genetics. Written by leading experts from medicine, education, psychology, ethics, counseling, and other disciplines studying fertility and genetics, the book contains nearly 70 chapters in seven sections. The introductory section deals with biology, business, morality and society in IVF and reproductive genetics; other sections focus on IVF outcomes, personal ethics and business, biology of the egg, sperm and embryo, implantation, IVF and society, and such 21st century topics as space travel and human reproduction, the disappearing male,and the future of motherhood. Includes bibliographic references and index. |
| era endometrial receptivity analysis: Clinical Case Studies for the Family Nurse Practitioner Leslie Neal-Boylan, 2011-11-28 Clinical Case Studies for the Family Nurse Practitioner is a key resource for advanced practice nurses and graduate students seeking to test their skills in assessing, diagnosing, and managing cases in family and primary care. Composed of more than 70 cases ranging from common to unique, the book compiles years of experience from experts in the field. It is organized chronologically, presenting cases from neonatal to geriatric care in a standard approach built on the SOAP format. This includes differential diagnosis and a series of critical thinking questions ideal for self-assessment or classroom use. |
| era endometrial receptivity analysis: Clinical In Vitro Fertilization C. Wood, A. Trounson, 2012-12-06 Man is entering a new era as a result of advances in human reproduction. Techniques have been developed to assist in the creation of man-artificial insemination and, now, in vitro fertilization (IVF). Soon, other new methods, based upon current advances of the IVF procedure, will develop to improve the quality of human reproduction. The book describes the conceptual framework and details of technique concerned with in vitro fertilization and embryo transfer (ET). Edwards and Steptoe first described the technique of IVF and ET and the subsequent births of two normal babies. Since then, the success rate of the system has been improved by the use of fertility drugs to provide more oocytes and preincubation to mature the oocyte before fertilization. As a result of the continued research from Melbourne and Cambridge, more than 100 babies have been born. A free interchange of information between the Cambridge and Melbourne groups has led to a predictable success rate of 15%-20% per laparoscopy, and infertility centres all over the world are now copying the techniques. It is an appropriate time to inform doctors and scientists to help them understand the various procedures involved in IVF and ET. While many advances will occur in the future, the establishment of high success rates in several of the critical steps in the procedure-oocyte pick-up rate (90%), fertilization (>90%) and early embryo development (70%-90% )-signifies that some of the new techniques are stabilized sufficiently to warrant transmission of information by text, rather than scientific journal. |
| era endometrial receptivity analysis: Blastocyst Implantation Koji Yoshinaga, 1989 |
| era endometrial receptivity analysis: Keto for Fertility Cookbook Robert Kiltz, Maria Emmerich, 2022 |
| era endometrial receptivity analysis: Human Assisted Reproductive Technology David K. Gardner, Botros R. M. B. Rizk, Tommaso Falcone, 2011-03-31 Human Assisted Reproductive Technology: Future Trends in Laboratory and Clinical Practice offers a collection of concise, practical review articles on cutting-edge topics within reproductive medicine. Each article presents a balanced view of clinically relevant information and looks ahead to how practice will change over the next five years. The clinical section discusses advances in reproductive surgery and current use of robotic surgery for tubal reversal and removal of fibroids. It looks into the refinement of surgical procedures for fertility preservation purposes. Chapters also discuss non-invasive diagnosis of endometriosis with proteomics technology, new concepts in ovarian stimulation and in the management of polycystic ovary syndrome, and evidence-based ART. The embryology section discusses issues ranging from three-dimensional in-vitro ovarian follicle culture, and morphometric and proteomics analysis of embryos, to oocyte and embryo cyropreservation. This forward-looking volume of review articles is key reading for reproductive medicine physicians, gynecologists, reproductive endocrinologists, urologists and andrologists. |
| era endometrial receptivity analysis: Hysteroscopy Andrea Tinelli, Luis Alonso Pacheco, Sergio Haimovich, 2018-02-12 This book offers a cutting-edge guide to hysteroscopy and provides readers with the latest and most essential information on procedure techniques, clinical advances and international developments in practice and treatment of endometrial pathology. Providing comprehensive coverage, it explains in detail every aspect of hysteroscopy, from diagnostics to hysteroscopic surgery. As such, it addresses the bases of hysteroscopy; pre-, intra- and post-hysteroscopy medications; intracavitary pathologies; fertility issues; and surgical implications and complications. At the same time, it also explores challenging and controversial topics, such as hysteroscopy and ART, submucous myomas, and uterine malformations. All topics are discussed by prominent experts in the field, and clearly organized and illustrated to help readers gain the most from each chapter. Accordingly, the book offers a valuable resource for all gynecologists working at hysteroscopy units, reproductive units, gynecological and oncological units, as well as a quick reference guide for all other physicians interested in the topic. |
| era endometrial receptivity analysis: Clinical Gynecology Eric J. Bieber, Joseph S. Sanfilippo, Ira R. Horowitz, Mahmood I. Shafi, 2015-04-23 Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings. |
| era endometrial receptivity analysis: Ultrasonography in Gynecology Botros R. M. B. Rizk, Elizabeth E. Puscheck, 2014-10-16 Ultrasonography is a cornerstone in the evaluation of gynecologic disease. This authoritative new book looks at the techniques of ultrasonography in both office and hospital settings, offering guidance on the optimal use of equipment and covering the full range of benign and malignant gynecologic disease as well as infertility. Ultrasonography in Gynecology offers extensive coverage of the diagnostic potential of ultrasound in gynecologic disease, from the moment the patient walks into the physician's office. All the different approaches in the ultrasonographic evaluation of disease – including 3D ultrasonography, 3D sonohysterography, Doppler imaging and pelvic floor imaging – are extensively covered, with color images throughout. Written and edited by leaders in the field of ultrasonography who have actively participated in national and international teaching courses, Ultrasonography in Gynecology is a must for all gynecologists dealing with infertility, endometriosis, uterine fibroids, gynecologic cancers, and many more gynecologic conditions. |
| era endometrial receptivity analysis: How Tobacco Smoke Causes Disease United States. Public Health Service. Office of the Surgeon General, 2010 This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products. |
| era endometrial receptivity analysis: Sexuality and Its Disorders Mike Abrams, 2016-10-07 Sexuality and Its Disorders explores sexuality from an evolutionary perspective using powerful, real-life case studies to help readers provide effective guidance around issues relating to sexuality. Drawing on his 30 years of clinical experience and research, author Mike Abrams provides a comprehensive, evidence-based, and clinically-oriented text with cutting-edge coverage throughout. Discussions include the physical and psychological development of sexual identity; the social aspects of sexual behavior; the many expressions of sexuality; cognitive behavior treatment of sexual problems; and more. The many perspectives of sexuality are examined with interviews and commentaries from major figures in the field—including David M. Buss, Helen Fisher, C. Sue Carter of Kinsey, Todd K. Shackelford, Ken Zucker, and Gordon Gallup—who discuss such topics as the origins of sexuality, the nature of love, the role of attachment, and the treatment of sexual problems. |
| era endometrial receptivity analysis: Individualized In-Vitro Fertilization Human M. Fatemi, Barbara Lawrenz, 2021-03-04 This book provides updates on the most recent developments in individualized infertility treatment resulting in improved outcomes. |
| era endometrial receptivity analysis: Ovum Implantation Moses Chiam Shelesnyak, 1969 |
| era endometrial receptivity analysis: Office Gynecology David Chelmow, Nicole W. Karjane, Hope A. Ricciotti, Amy E. Young, 2019-01-31 Around 100 common clinical problems feature in quick-read cases, alongside evidence-based recommendations and current guidelines. |
| era endometrial receptivity analysis: Donor Insemination C. L. R. Barratt, Ian Douglas Cooke, 1993-05-13 Provides clear guidelines on the advantages, disadvantages and limitations of the use of donor insemination to treat infertility. |
| era endometrial receptivity analysis: Infertility and Assisted Reproduction Botros Rizk, Juan A. Garcia-Velasco, Hassan N. Sallam, Antonis Makrigiannakis, 2008-09-15 Assisted reproductive technology (ART) is available to two-thirds of the world's population, and world-class experts, representing research from 18 different countries, have contributed to this groundbreaking textbook, detailing the techniques and philosophies behind medical procedures of infertility and assisted reproduction. This is one of the most rapidly changing and hotly debated fields in medicine. Different countries have different restrictions on the research techniques that can be applied to this field, and, therefore, experts from around the world bring varied and unique authorities to different subjects in reproductive technology. Encompassing the latest research into the physiology of reproduction, infertility evaluation and treatment, and assisted reproduction, it concludes with perspectives on the ethical dilemmas faced by clinicians and professionals. This book will be the definitive resource for those working in the areas of reproductive medicine world wide. |
| era endometrial receptivity analysis: Human Reproductive Genetics Juan A. Garcia-Velasco, Emre Seli, 2020-04-19 Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction. - Provides an essential reference for clinicians involved in reproductive medicine - Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients - Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more |
| era endometrial receptivity analysis: The One in Eight Monica Brodovsky, 2021-04-04 One in eight couples in the U.S. struggle with infertility. This book brings to light those struggles, in its many faces and forms, through the voices of individuals and couples. They have all fearlessly put their stories out into the world to help educate, advocate, and reflect upon this very important topic that is too often misunderstood and stigmatized. It's time to normalize the conversation around infertility. If you too are struggling, please remember that you are not alone. |
| era endometrial receptivity analysis: Assisted Reproductive Technology Success Rates , 2003 |
| era endometrial receptivity analysis: Human Reproductive and Prenatal Genetics Peter C.K. Leung, Jie Qiao, 2023-03-22 **Selected for Doody's Core Titles® 2024 in Clinical Genetics** Human Reproductive and Prenatal Genetics, Second Edition provides application-driven coverage of key topics in human reproductive and prenatal genetics, including genetic control underlying the development of the reproductive tracts and gametogenesis, the genetics of fertilization and implantation, the genetic basis of female and male infertility, as well as genetic and epigenetic aspects of assisted reproduction. Also examined are the genetics and epigenetics of the placenta in normal and abnormal pregnancy, preimplantation genetic diagnosis and screening, and cutting-edge advances in noninvasive prenatal screening, prenatal genetic counseling, and bioethical and medicolegal aspects of relevance in the lab and clinic. This new edition has been fully revised to address new and evolving technologies in human reproductive genetics, with new chapters added on chromatin landscapes and sex determination, genetic alterations of placental development and preeclampsia, metabolism and inflammation in PCOS, pre-implantational genetic testing, maternal genetic disorders, bioethics, and future applications. - Features chapter contributions from leading international scientists and clinicians - Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization, placental development, embryo implantation, in vitro culture of the human embryo for the study of post-implantation development, and more - Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics-based approaches - Includes all new chapters on evolving technologies and recent genetic discoveries of relevance to reproductive medicine |
| era endometrial receptivity analysis: How to Prepare the Endometrium to Maximize Implantation Rates and IVF Success Gabor Kovacs, Lois Salamonsen, 2019-01-17 The last step in the IVF treatment cycle, embryo transfer, is also the process with the highest failure rate. No matter how good the laboratory technique is, a successful pregnancy will not be achieved without meticulous preparation of the uterus to accept the embryo. This book reviews the scientific evidence on endometrial receptivity, including histological, hormonal, biochemical, and immunological factors. Practical and concise, it supports gynecologists and embryologists to make evidence-based decisions that can influence the success rates of implantation and live births. Part of a series of books offering treatments and strategies for fertility and conception to optimize IVF outcomes, this volume is for all clinicians and embryologists working in reproductive medicine. |
| era endometrial receptivity analysis: Advances in Genetics Jeffrey C. Hall, 2005-11-07 The field of genetics is rapidly evolving and new medical breakthroughs are occurring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. |
| era endometrial receptivity analysis: Hormonal Contraception and Post-menopausal Hormonal Therapy IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 1999 Evaluates evidence for an increased risk of cancer in women using combined oral contraceptives, progestogen-only hormonal contraceptives, post-menopausal estrogen therapy, and post-menopausal estrogen-progestogen therapy. Although the carcinogenicity of these preparations has been extensively investigated, the book stresses the many complex methodological issues that must be considered when interpreting findings and weighing results. Evidence of an association between use of these preparations and positive effects on health, including a reduced risk of some cancers, is also critically assessed. The first and most extensive monograph evaluates evidence of an association between the use of combined oral contraceptives and cancer at nine sites. Concerning breast cancer, the evaluation concludes that, even if the association is causal, the excess risk for breast cancer associated with patterns of use that are typical today is very small. Studies of predominantly high-dose preparations found an increased risk of hepatocellular carcinoma in the absence of hepatitis viruses. Citing these findings, the evaluation concludes that there is sufficient evidence in humans for the carcinogenicity of combined oral contraceptives. The evaluation also found sufficient evidence for the carcinogenicity of some, but not all, combined preparations in animals. Combined oral contraceptives were classified as carcinogenic to humans. The evaluation also cites conclusive evidence that these agents have a protective effect against cancers of the ovary and endometrium. Progestogen-only contraceptives are evaluated in the second monograph, which considers the association with cancer at six sites. The evaluation found no evidence of an increased risk for breast cancer. Although the evaluation found sufficient evidence in animals for the carcinogenicity of medroxyprogesterone acetate, evidence for the carcinogenicity of progestogen-only contraceptives in humans was judged inadequate. Progestogen-only contraceptives were classified as possibly carcinogenic to humans. The third monograph, on post-menopausal estrogen therapy, considers evidence of an association with cancer at eight sites. Findings from a large number of epidemiological studies indicate a small increase in the risk of breast cancer in women who have used these preparations for five years or more. Studies consistently show an association between use of post-menopausal estrogen therapy and an increased risk for endometrial cancer. Data on the association with other cancers were either inconclusive or suggested no effect on risk. The evaluation concludes that post-menopausal estrogen therapy is carcinogenic to humans. The final monograph evaluates the association between the use of post-menopausal estrogen-progestogen therapy and cancer at four sites. The evaluation of limited data on breast cancer found an increased relative risk observed with long-term use. Data were judged insufficient to assess the effects of past use and of different progestogen compounds, doses, and treatment schedules. For endometrial cancer, the evaluation found an increase in risk relative to non-users when the progestogen was added to the cycle for 10 days or fewer. Post-menopausal estrogen-progestogen therapy was classified as possibly carcinogenic to humans. Concerning post-menopausal therapy in general, the book notes that evidence of carcinogenic risks must be placed in perspective of potential benefits. The prevention of osteoporotic fractures is cited as the best-established benefit. Evidence also suggests that estrogen prevents heart disease and may prevent memory loss and dementia. |
Endometrial Receptivity Analysis (ERA) (+ EMMA & ALICE) …
What is Endometrial Receptivity Analysis (ERA)? ERA is the first diagnostic test that determines each woman’s unique personalized embryo transfer timing, therefore synchronizing the …
Endometrial Receptivity Assay (ERA) - onefertility.com
Endometrial Receptivity Array (ERA) is a test to determine the ideal cycle day for you to have a frozen embryo transfer. It involves taking medications to prepare the lining of the uterus for an …
The study on the clinical efficacy of endometrial receptivity …
Endometrial receptivity status can be predicted through computer analysis. Specific steps and criteria for ERA testing are described in the supplemental materials.
Endometrial Receptivity Array (ERA) - Editions ESKA
To learn about endometrial receptivity array (ERA), for the diagnosis of the endometrial factor and its surrogate therapeutic option: personalized ET (pET).
Ficha ERA Study B - igenomix.eu
Improve ART outcomes with personalized embryo transfer (pET) according to endometrial receptivity analysis (ERA) in advanced-age RIF patients, by utilizing donor oocytes and …
Endometrial Receptivity Analysis (ERA): data versus opinions
Extending this application of endometrial transcriptomics, the endometrial receptivity analysis (ERA) test couples next-generation sequenc-ing (NGS) to a computational predictor to identify...
Endometrial receptivity array before frozen embryo transfer …
Nov 19, 2022 · Objective: To investigate the impact of endometrial receptivity array (ERA) before frozen embryo transfer in patients undergoing in vitro fertilization (IVF). There is a lack of …
Performing Personalized Embryo Transfer (Pet) Using the …
We performed the endometrial receptivity analysis in the next cycle to determine the personalized window of implantation. ERA was performed in an HRT cycle in which estradiol valerate was …
Endometrial Receptivity Analysis ERA - IGENOMIX
Why choose Igenomix's ERA test? June 2019 ERA is backed by 33 publications 29 from Igenomix and 4 external publications. Randomized study in progress to assess its applicability in …
Endometrial Receptivity TRIO
Analysis of Infectious Chronic Endometritis (ALICE) detects the most frequent bacteria that can cause chronic endometritis. Endometrial Receptivity Array (ERA) is a test to determine the …
Endometrial receptivity, to test or not to test: the evidence on ...
Evaluation of the receptive window/timing (e.g., Endometrial Receptivity Assay [ERA]), endometrial. Received July 14, 2022; revised October 18, 2022; accepted November 2, 2022. …
Endometrial Receptivity Analysis (ERA) (+ EMMA & ALICE)
What is Endometrial Receptivity Analysis (ERA)? ERA is the first diagnostic test that determines each woman’s unique personalized embryo transfer timing, therefore synchronizing the …
Endometrial receptivity (ERA), Endometrial Microbiome …
The “endometrial health pack” by Igenomix (Spain) was recently presented at a medical conference as a way of testing RIF. This test consists of an endometrial biopsy that is sent for …
5 reasons to recommend the original endometrial receptivity …
ERA is the endometrial receptivity test with the highest published clinical rates for patients with RIF. (Jia et al., 2022 vs Ohara et al., 2022) RIF patients who undergo a pET guided by ERA …
Endometrial Receptivity (ERA), Endometrial Microbiome …
The EMMA test looks at the endometrial microbiome and determines the healthy bacteria levels that may play a role in the implantation of an embryo. Probiotic treatment may be suggested to …
Backed by science, trusted by experts — a proven solution for …
Backed by the analysis of endometrial bi-opsies from more than 200,000 women worldwide, ERA is the most advanced en-dometrial receptivity test available. Sup- ... In fact, ERA is the only …
5 reasons to recommend the original endometrial receptivity …
ERA is the endometrial receptivity test with the highest published clinical rates for patients with RIF. RIF patients who undergo a pET guided by ERA found to have similar outcomes to those …
Endometrial Receptivity Analysis - IGENOMIX
ERA® allows a personalized embryo transfer by synchronizing the embryo with the patient window of implanta-tion analyzing 248 genes, much more than any other tests in the market.
Endometrial Receptivity Analysis (ERA) (+ EMMA & ALICE) …
What is Endometrial Receptivity Analysis (ERA)? ERA is the first diagnostic test that determines each woman’s unique personalized embryo transfer timing, therefore synchronizing the …
Endometrial Receptivity Assay (ERA) - onefertility.com
Endometrial Receptivity Array (ERA) is a test to determine the ideal cycle day for you to have a frozen embryo transfer. It involves taking medications to prepare the lining of the uterus for an …
The study on the clinical efficacy of endometrial receptivity …
Endometrial receptivity status can be predicted through computer analysis. Specific steps and criteria for ERA testing are described in the supplemental materials.
Endometrial Receptivity Array (ERA) - Editions ESKA
To learn about endometrial receptivity array (ERA), for the diagnosis of the endometrial factor and its surrogate therapeutic option: personalized ET (pET).
Ficha ERA Study B - igenomix.eu
Improve ART outcomes with personalized embryo transfer (pET) according to endometrial receptivity analysis (ERA) in advanced-age RIF patients, by utilizing donor oocytes and …
Endometrial Receptivity Analysis (ERA): data versus …
Extending this application of endometrial transcriptomics, the endometrial receptivity analysis (ERA) test couples next-generation sequenc-ing (NGS) to a computational predictor to identify...
Endometrial receptivity array before frozen embryo transfer …
Nov 19, 2022 · Objective: To investigate the impact of endometrial receptivity array (ERA) before frozen embryo transfer in patients undergoing in vitro fertilization (IVF). There is a lack of …
A complete view of endometrial health - IGENOMIX
ERA (Endometrial Receptivity Analysis), determines the optimal time in the endometrial cycle to perform embryo transfer. Thus, ERA can increase the chances of pregnancy by synchronizing …
Performing Personalized Embryo Transfer (Pet) Using the …
We performed the endometrial receptivity analysis in the next cycle to determine the personalized window of implantation. ERA was performed in an HRT cycle in which estradiol valerate was …
Endometrial Receptivity Analysis ERA - IGENOMIX
Why choose Igenomix's ERA test? June 2019 ERA is backed by 33 publications 29 from Igenomix and 4 external publications. Randomized study in progress to assess its applicability in …
Endometrial Receptivity TRIO
Analysis of Infectious Chronic Endometritis (ALICE) detects the most frequent bacteria that can cause chronic endometritis. Endometrial Receptivity Array (ERA) is a test to determine the …
Endometrial receptivity, to test or not to test: the evidence on ...
Evaluation of the receptive window/timing (e.g., Endometrial Receptivity Assay [ERA]), endometrial. Received July 14, 2022; revised October 18, 2022; accepted November 2, 2022. …
Endometrial Receptivity Analysis (ERA) (+ EMMA & ALICE)
What is Endometrial Receptivity Analysis (ERA)? ERA is the first diagnostic test that determines each woman’s unique personalized embryo transfer timing, therefore synchronizing the …
Endometrial receptivity (ERA), Endometrial Microbiome …
The “endometrial health pack” by Igenomix (Spain) was recently presented at a medical conference as a way of testing RIF. This test consists of an endometrial biopsy that is sent for …
5 reasons to recommend the original endometrial receptivity …
ERA is the endometrial receptivity test with the highest published clinical rates for patients with RIF. (Jia et al., 2022 vs Ohara et al., 2022) RIF patients who undergo a pET guided by ERA …
EndomeTRIO Manual - igenomix.com
ERA (Endometrial Receptivity Analysis), determines the optimal time in the endometrial cycle to perform embryo transfer. Thus, ERA can increase the chances of pregnancy by synchronizing …
Endometrial Receptivity (ERA), Endometrial Microbiome …
The EMMA test looks at the endometrial microbiome and determines the healthy bacteria levels that may play a role in the implantation of an embryo. Probiotic treatment may be suggested to …
Backed by science, trusted by experts — a proven solution …
Backed by the analysis of endometrial bi-opsies from more than 200,000 women worldwide, ERA is the most advanced en-dometrial receptivity test available. Sup- ... In fact, ERA is the only …
5 reasons to recommend the original endometrial receptivity …
ERA is the endometrial receptivity test with the highest published clinical rates for patients with RIF. RIF patients who undergo a pET guided by ERA found to have similar outcomes to those …
